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carnitine and Complications, Pregnancy

carnitine has been researched along with Complications, Pregnancy in 34 studies

Research Excerpts

ExcerptRelevanceReference
"The crucial role of L-carnitine in pregnancy metabolism suggests that nutritional supplementation of this amino acid can be offered to women who are either overweight or obese at the beginning of the pregnancy."7.79Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tipi-Akbas, P; Yilmazer, M, 2013)
"Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency is a mitochondrial fatty acid beta-oxidation defect characterized by accumulation of long-chain hydroxyacylcarnitine intermediates and female carriers of this disorder are in risk for pregnancy complications."7.76Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication? ( Eskelin, PM; Laitinen, KA; Tyni, TA, 2010)
"Close observation of plasma amino acid, carnitine, and acylcarnitine profiles was performed in a patient with IVA that completed uneventful pregnancy."7.76Maternal isovaleric acidemia: observation of distinctive changes in plasma amino acids and carnitine profiles during pregnancy. ( Castelnovi, C; Moseley, K; Yano, S, 2010)
"We report management through pregnancy and delivery of a patient with carnitine deficiency who had reduced carnitine transport in fibroblasts, but no mutations in the OCTN2 gene."7.74Carnitine deficiency in pregnancy. ( Abdenur, JE; Donnelly, CT; Hameed, AB; Wing, DA, 2007)
"We report on a favourable pregnancy in a woman affected by mut- methylmalonic acidaemia."7.71Successful pregnancy in a woman with mut- methylmalonic acidaemia. ( Baiocco, F; Boenzi, S; Deodato, F; Dionisi-Vici, C; Rizzo, C; Sabetta, G, 2002)
"In this study the correlations between the concentration of carnitine and an increasing glucose intolerance in women with untreated, non insulin dependent gestational diabetes (GDM) were examined."7.71[The concentration of carnitine in the last trimester of pregnancy subject to glucose tolerance]. ( Günter, HH; Oehler, K; Peulecke, W; Scharf, A; Schumann, G; Sohn, C, 2002)
"We report on 2 women with organic acidemias, one with classical maple syrup urine disease and another with mild propionic acidemia in which protein restricted diets and carnitine supplementation were successfully employed to manage pregnancies."7.68Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. ( Barness, LA; Davidson, SR; Harding, CO; Van Calcar, SC; Wolff, JA, 1992)
"Although frank symptomatic biotin deficiency is rare, some evidence suggests that marginal biotin deficiency occurs spontaneously in a substantial proportion of women during normal human pregnancy and might confer an increased risk of birth defects."4.95Biotin: From Nutrition to Therapeutics. ( Mock, DM, 2017)
"21]) were associated with higher odds of antepartum depression and 4 metabolites (betaine [OR = =0."3.96Metabolomic markers of antepartum depression and suicidal ideation. ( Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA, 2020)
"Targeted metabolomic assays of clinical metabolites, amino acids, and acylcarnitines were performed on fasting and 1-h postglucose serum samples from European ancestry, Afro-Caribbean, Thai, and Mexican American mothers (400 from each ancestry group) who participated in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study and underwent an oral glucose tolerance test at ∼28 weeks gestation."3.85Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups. ( Bain, JR; Ilkayeva, OR; Jacob, S; Lowe, LP; Lowe, WL; Metzger, BE; Muehlbauer, MJ; Newgard, CB; Nodzenski, M; Reisetter, AC; Scholtens, DM; Stevens, RD, 2017)
"The crucial role of L-carnitine in pregnancy metabolism suggests that nutritional supplementation of this amino acid can be offered to women who are either overweight or obese at the beginning of the pregnancy."3.79Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tipi-Akbas, P; Yilmazer, M, 2013)
"Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency is a mitochondrial fatty acid beta-oxidation defect characterized by accumulation of long-chain hydroxyacylcarnitine intermediates and female carriers of this disorder are in risk for pregnancy complications."3.76Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication? ( Eskelin, PM; Laitinen, KA; Tyni, TA, 2010)
"Close observation of plasma amino acid, carnitine, and acylcarnitine profiles was performed in a patient with IVA that completed uneventful pregnancy."3.76Maternal isovaleric acidemia: observation of distinctive changes in plasma amino acids and carnitine profiles during pregnancy. ( Castelnovi, C; Moseley, K; Yano, S, 2010)
"We report management through pregnancy and delivery of a patient with carnitine deficiency who had reduced carnitine transport in fibroblasts, but no mutations in the OCTN2 gene."3.74Carnitine deficiency in pregnancy. ( Abdenur, JE; Donnelly, CT; Hameed, AB; Wing, DA, 2007)
"We report on a favourable pregnancy in a woman affected by mut- methylmalonic acidaemia."3.71Successful pregnancy in a woman with mut- methylmalonic acidaemia. ( Baiocco, F; Boenzi, S; Deodato, F; Dionisi-Vici, C; Rizzo, C; Sabetta, G, 2002)
"In this study the correlations between the concentration of carnitine and an increasing glucose intolerance in women with untreated, non insulin dependent gestational diabetes (GDM) were examined."3.71[The concentration of carnitine in the last trimester of pregnancy subject to glucose tolerance]. ( Günter, HH; Oehler, K; Peulecke, W; Scharf, A; Schumann, G; Sohn, C, 2002)
"We report on 2 women with organic acidemias, one with classical maple syrup urine disease and another with mild propionic acidemia in which protein restricted diets and carnitine supplementation were successfully employed to manage pregnancies."3.68Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. ( Barness, LA; Davidson, SR; Harding, CO; Van Calcar, SC; Wolff, JA, 1992)
"Obesity is an important worldwide public health problem and considered a disease of chronic low-grade inflammation."2.80Effect of L-carnitine supplementation in comparison with moderate aerobic training on serum inflammatory parameters in healthy obese women. ( Jafari, A; Karimi, M; Rafraf, M, 2015)
"Birth weight was higher in the G allele homozygotes of the CHDH rs2289205 than in the minor allele carriers: GG: 3398 ± 64 g; GA+AA: 3193 ± 76 g."1.48PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women. ( Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A, 2018)
"Her pregnancy was uncomplicated."1.40Methylmalonic acidaemia in pregnancy. ( Den Hartog, M; Eyskens, F; Jacquemyn, Y, 2014)
"Although vitamin B12 deficiency is not a primary target of newborn screening (NBS) programs, measurements of propionylcarnitine (C3) and its ratios with acetylcarnitine (C3/C2) and palmitoylcarnitine (C3/C16) may incidentally identify vitamin B12-deficient newborns."1.40Serum vitamin B12 levels during the first trimester of pregnancy correlate with newborn screening markers of vitamin B12 deficiency. ( Dayaldasani, A; Pérez-Valero, V; Rodríguez-Espinosa, M; Rueda, I; Ruiz-Escalera, J; Yahyaoui, R, 2014)
"The pregnancy was uneventful and the delivery at term."1.36Treatment of cobalamin C (cblC) deficiency during pregnancy. ( Brunel-Guitton, C; Costa, T; Lambert, M; Mitchell, GA, 2010)
"She had no phenotypic feature of holocarboxylase synthetase deficiency, most importantly no episodes ever of acute metabolic acidosis."1.35Positive newborn screen in the biochemically normal infant of a mother with treated holocarboxylase synthetase deficiency. ( Barshop, BA; Gangoiti, J; Nyhan, WL; Willis, M, 2009)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's3 (8.82)18.2507
2000's9 (26.47)29.6817
2010's16 (47.06)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Mitro, SD1
Larrabure-Torrealva, GT1
Sanchez, SE1
Molsberry, SA1
Williams, MA1
Clish, C1
Gelaye, B1
Jacob, S1
Nodzenski, M1
Reisetter, AC1
Bain, JR1
Muehlbauer, MJ1
Stevens, RD1
Ilkayeva, OR1
Lowe, LP1
Metzger, BE1
Newgard, CB1
Scholtens, DM1
Lowe, WL1
Mock, DM1
Chmurzynska, A1
Seremak-Mrozikiewicz, A1
Malinowska, AM1
Różycka, A1
Radziejewska, A1
Szwengiel, A1
Kurzawińska, G1
Barlik, M1
Jagodziński, PP1
Drews, K1
Rossi, C1
Cicalini, I1
Zucchelli, M1
di Ioia, M1
Onofrj, M1
Federici, L1
Del Boccio, P1
Pieragostino, D1
Tipi-Akbas, P1
Arioz, DT1
Kanat-Pektas, M1
Koken, T1
Koken, G1
Yilmazer, M1
Jacquemyn, Y1
Den Hartog, M1
Eyskens, F1
Scolamiero, E1
Villani, GR1
Ingenito, L1
Pecce, R1
Albano, L1
Caterino, M1
di Girolamo, MG1
Di Stefano, C1
Franzese, I1
Gallo, G1
Ruoppolo, M1
Romigi, A1
Liguori, C1
Izzi, F1
Albanese, M1
Marchi, A1
Mancini, C1
Tarquini, E1
Mercuri, NB1
Placidi, F1
Rafraf, M1
Karimi, M1
Jafari, A1
Dayaldasani, A1
Ruiz-Escalera, J1
Rodríguez-Espinosa, M1
Rueda, I1
Pérez-Valero, V1
Yahyaoui, R1
Nyhan, WL1
Willis, M1
Barshop, BA1
Gangoiti, J1
Eskelin, PM1
Laitinen, KA1
Tyni, TA1
Mendez-Figueroa, H1
Shchelochkov, OA1
Shaibani, A1
Aagaard-Tillery, K1
Shinawi, MS1
Castelnovi, C1
Moseley, K1
Yano, S1
Brunel-Guitton, C1
Costa, T1
Mitchell, GA1
Lambert, M1
Sarafoglou, K1
Rodgers, J1
Hietala, A1
Matern, D1
Bentler, K1
Ituk, US1
Allen, TK1
Habib, AS1
Deodato, F1
Rizzo, C1
Boenzi, S1
Baiocco, F1
Sabetta, G1
Dionisi-Vici, C1
Günter, HH1
Peulecke, W1
Oehler, K1
Scharf, A1
Schumann, G1
Sohn, C1
Bok, LA1
Vreken, P1
Wijburg, FA1
Wanders, RJ1
Gregersen, N1
Corydon, MJ1
Waterham, HR1
Duran, M1
Wu, SP1
Shyu, MK1
Liou, HH1
Gau, CS1
Lin, CJ1
Campbell, CD1
Ganesh, J1
Ficicioglu, C1
Donnelly, CT1
Hameed, AB1
Abdenur, JE1
Wing, DA1
Kong, XF1
Zhang, XX1
Yu, YY1
Shi, Q1
La, DD1
Zhu-Ge, CD1
Deng, L1
Gong, QM1
Shen, BY1
Peng, CH1
Li, HW1
Bargen-Lockner, C1
Hahn, P1
Wittmann, B1
Treem, WR2
Rinaldo, P1
Hale, DE1
Stanley, CA1
Millington, DS1
Hyams, JS1
Jackson, S1
Turnbull, DM1
Borum, PR1
Broquist, HP1
Salonen, V1
Nikoskelainen, J1
Heinonen, OJ1
Kalimo, H1
Aula, P1
Van Calcar, SC1
Harding, CO1
Davidson, SR1
Barness, LA1
Wolff, JA1
Nagao, M1
Tsuchiyama, A1
Aoyama, T1
Mori, T1
Oyanagi, K1
Acosta, PB1
Stepnick-Gropper, S1
Salzer, H1
Lohninger, A1
Sevelda, P1
Legenstein, E1

Reviews

2 reviews available for carnitine and Complications, Pregnancy

ArticleYear
Biotin: From Nutrition to Therapeutics.
    The Journal of nutrition, 2017, Volume: 147, Issue:8

    Topics: Animals; Biotin; Biotinylation; Carnitine; Female; Gene Expression; Hormones; Humans; Multiple Scler

2017
New developments in the pathophysiology, clinical spectrum, and diagnosis of disorders of fatty acid oxidation.
    Current opinion in pediatrics, 2000, Volume: 12, Issue:5

    Topics: Acetyl Coenzyme A; Carnitine; Fatty Acids; Female; Fetal Diseases; Humans; Infant; Lipid Metabolism,

2000

Trials

1 trial available for carnitine and Complications, Pregnancy

ArticleYear
Effect of L-carnitine supplementation in comparison with moderate aerobic training on serum inflammatory parameters in healthy obese women.
    The Journal of sports medicine and physical fitness, 2015, Volume: 55, Issue:11

    Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Carnitine; Dietary Supplements; Double-Blind

2015

Other Studies

31 other studies available for carnitine and Complications, Pregnancy

ArticleYear
Metabolomic markers of antepartum depression and suicidal ideation.
    Journal of affective disorders, 2020, 02-01, Volume: 262

    Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Dep

2020
Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups.
    Diabetes care, 2017, Volume: 40, Issue:7

    Topics: Amino Acids; Blood Glucose; Body Mass Index; Carnitine; Cohort Studies; Female; Gestational Age; Glu

2017
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
    Nutrition research (New York, N.Y.), 2018, Volume: 56

    Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltr

2018
Metabolomic Signature in Sera of Multiple Sclerosis Patients during Pregnancy.
    International journal of molecular sciences, 2018, Nov-14, Volume: 19, Issue:11

    Topics: Adult; Amino Acids; Biomarkers; Carnitine; Case-Control Studies; Female; Gonadal Steroid Hormones; H

2018
Lowered serum total L-carnitine levels are associated with obesity at term pregnancy.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:15

    Topics: Adult; Body Height; Body Mass Index; Carnitine; Dietary Supplements; Female; Fetal Weight; Gestation

2013
Methylmalonic acidaemia in pregnancy.
    BMJ case reports, 2014, Mar-31, Volume: 2014

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Calcium Carbonate; Carnitine; Diet, Protein-Restricted;

2014
Maternal vitamin B12 deficiency detected in expanded newborn screening.
    Clinical biochemistry, 2014, Volume: 47, Issue:18

    Topics: Carnitine; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal S

2014
Oral L-carnitine as treatment for narcolepsy without cataplexy during pregnancy: a case report.
    Journal of the neurological sciences, 2015, Jan-15, Volume: 348, Issue:1-2

    Topics: Adult; Carnitine; Female; Humans; Narcolepsy; Pregnancy; Pregnancy Complications

2015
Serum vitamin B12 levels during the first trimester of pregnancy correlate with newborn screening markers of vitamin B12 deficiency.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2014, Volume: 84, Issue:1-2

    Topics: Acetylcarnitine; Adolescent; Adult; Biomarkers; Carnitine; Diet; Female; Gestational Age; Humans; In

2014
Positive newborn screen in the biochemically normal infant of a mother with treated holocarboxylase synthetase deficiency.
    Journal of inherited metabolic disease, 2009, Volume: 32 Suppl 1

    Topics: Adult; Biotin; Carnitine; False Positive Reactions; Female; Holocarboxylase Synthetase Deficiency; H

2009
Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication?
    Molecular genetics and metabolism, 2010, Volume: 100, Issue:2

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acute Disease; Adult; Carnitine; Fatty Liver; Female; Humans; Lipi

2010
Clinical and biochemical improvement of very long-chain acyl-CoA dehydrogenase deficiency in pregnancy.
    Journal of perinatology : official journal of the California Perinatal Association, 2010, Volume: 30, Issue:8

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Carnitine; Female; Humans; Infant, Newborn; Lipid Metabolism, In

2010
Maternal isovaleric acidemia: observation of distinctive changes in plasma amino acids and carnitine profiles during pregnancy.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Dec-14, Volume: 411, Issue:23-24

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Carnitine; Female; Humans; Infant, Newborn; Isova

2010
Treatment of cobalamin C (cblC) deficiency during pregnancy.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Amino Acid Metabolism, Inborn Errors; Aspirin; Carnitine; Carrier Proteins; Cells, Cultured; Combine

2010
Expanded newborn screening for detection of vitamin B12 deficiency.
    JAMA, 2011, Mar-23, Volume: 305, Issue:12

    Topics: Carnitine; Female; Humans; Infant, Newborn; Minnesota; Neonatal Screening; Pregnancy; Pregnancy Comp

2011
The peripartum management of a patient with glutaric aciduria type 1.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Anesthesia, Obstetrical; Anesthesia, Spinal; Brain Diseases, M

2013
Successful pregnancy in a woman with mut- methylmalonic acidaemia.
    Journal of inherited metabolic disease, 2002, Volume: 25, Issue:2

    Topics: Adult; Carnitine; Female; Humans; Metabolism, Inborn Errors; Methylmalonic Acid; Pregnancy; Pregnanc

2002
[The concentration of carnitine in the last trimester of pregnancy subject to glucose tolerance].
    Zentralblatt fur Gynakologie, 2002, Volume: 124, Issue:11

    Topics: Adult; Biomarkers; Blood Glucose; Carnitine; Diabetes, Gestational; Female; Glucose Intolerance; Glu

2002
Short-chain Acyl-CoA dehydrogenase deficiency: studies in a large family adding to the complexity of the disorder.
    Pediatrics, 2003, Volume: 112, Issue:5

    Topics: Amino Acid Substitution; Anemia, Hemolytic; Butyryl-CoA Dehydrogenase; Carnitine; Consanguinity; DNA

2003
Interaction between anticonvulsants and human placental carnitine transporter.
    Epilepsia, 2004, Volume: 45, Issue:3

    Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techn

2004
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
    Haematologica, 2005, Volume: 90, Issue:12 Suppl

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine;

2005
Carnitine deficiency in pregnancy.
    Obstetrics and gynecology, 2007, Volume: 110, Issue:2 Pt 2

    Topics: Adult; Carnitine; Cesarean Section; Female; Fibroblasts; Humans; Pregnancy; Pregnancy Complications;

2007
No mutation was found in the alpha-subunit of the mitochondrial tri-functional protein in one patient with severe acute fatty liver of pregnancy and her relatives.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:12

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adult; Carnitine; Cytosine; Family; Fatty Liver; Female; Guanine;

2007
Plasma carnitine in pregnancy.
    American journal of obstetrics and gynecology, 1981, Jun-15, Volume: 140, Issue:4

    Topics: Adolescent; Adult; Carnitine; Female; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy C

1981
Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:2

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acute Disease; Adult; Carnitine; Cells, Cultured; Child; Child, Pr

1994
Lysine deficiency and carnitine in male and female rats.
    The Journal of nutrition, 1977, Volume: 107, Issue:7

    Topics: Animals; Body Weight; Carnitine; Dietary Proteins; Epididymis; Female; Glutens; Liver; Lysine; Male;

1977
[Carnitine deficiency and severe nausea-induced thiamine deficiency causing a metabolic crisis].
    Duodecim; laaketieteellinen aikakauskirja, 1992, Volume: 108, Issue:11

    Topics: Adult; Carnitine; Female; Humans; Hyperemesis Gravidarum; Lipid Metabolism; Metabolic Diseases; Naus

1992
Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia.
    American journal of medical genetics, 1992, Nov-15, Volume: 44, Issue:5

    Topics: Adult; Amino Acids; Carbon-Carbon Ligases; Carnitine; Citrates; Citric Acid; Female; Fetal Growth Re

1992
Secondary carnitine deficiency in the newborn period in twins of a mother with partial ornithine transcarbamylase deficiency.
    The Journal of pediatrics, 1989, Volume: 115, Issue:4

    Topics: Carnitine; Diseases in Twins; Female; Humans; Infant, Newborn; Ornithine Carbamoyltransferase Defici

1989
Problems related to diet management of maternal phenylketonuria.
    Journal of inherited metabolic disease, 1986, Volume: 9 Suppl 2

    Topics: alpha-Linolenic Acid; Carnitine; Cations, Divalent; Cell Membrane Permeability; Cholesterol; Dietary

1986
[Carnitine for the stimulation of fetal lung maturation. Clinical case report].
    Gynakologische Rundschau, 1985, Volume: 25, Issue:2

    Topics: Adult; Betamethasone; Carnitine; Female; Fetal Organ Maturity; Humans; Infant, Newborn; Lung; Male;

1985