carnitine has been researched along with Chronic Kidney Diseases in 31 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-carnitine is an amino acid derivative that is thought to be helpful for treating renal anemia in hemodialysis patients." | 9.12 | Effect of L-carnitine supplementation on renal anemia in patients on hemodialysis: a meta-analysis. ( Deng, J; Ou, J; Xie, Z; Xue, C; Zhu, Y, 2021) |
| "In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion." | 7.88 | Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018) |
| "Given the significant reductions in IL-6 and FBS levels, L-carnitine supplementation appeared to have some positive effects on the inflammation, blood glucose control, and prevention of cardiovascular events in these patients, as well as the improvement of quality of life." | 5.51 | Effect of L-Carnitine Supplementation on Inflammatory Markers and Serum Glucose in Hemodialysis Children: A Randomized, Placebo-Controlled Clinical Trial. ( Hamedi-Kalajahi, F; Imani, H; Mojtahedi, S; Shabbidar, S, 2022) |
| "L-carnitine is an amino acid derivative that is thought to be helpful for treating renal anemia in hemodialysis patients." | 5.12 | Effect of L-carnitine supplementation on renal anemia in patients on hemodialysis: a meta-analysis. ( Deng, J; Ou, J; Xie, Z; Xue, C; Zhu, Y, 2021) |
| "In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion." | 3.88 | Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018) |
| "As carnitine plays a key role in lipid metabolism and because plasma levels are reduced in hemodialysis patients, the aim of this study was to determine the effects of L-carnitine supplementation on serum lipid profiles, apolipoproteins, and free carnitine (FC) levels." | 3.01 | Effect of L-carnitine supplementation on lipid profile and apolipoproteins in children on hemodialysis: a randomized placebo-controlled clinical trial. ( Fahimi, D; Hamedi-Kalajahi, F; Imani, H; Mojtahedi, SY; Shabbidar, S; Zarezadeh, M, 2021) |
| "No L-carnitine effect was detected on parathyroid hormone (PTH) or FGF23 during the study period where PTH slightly decreased over time, whereas FGF23 increased." | 2.87 | Effects of L-Carnitine on Mineral Metabolism in the Multicentre, Randomized, Double Blind, Placebo-Controlled CARNIDIAL Trial. ( Allouache, M; Assogba, U; Bassilios, N; Chonchol, MB; Debure, A; Depreneuf, H; Mercadal, L; Prié, D; Servais, A; Tezenas du Montcel, S, 2018) |
| "Carnitine plays a pivotal role in energy synthesis through β-oxidation in mitochondria." | 1.62 | Kinetics of Serum Carnitine Fractions in Patients with Chronic Kidney Disease Not on Dialysis. ( Fukami, K; Ito, S; Kaida, Y; Kinoshita, Y; Kodama, G; Nakayama, Y; Tashiro, K; Yano, J; Yokota, Y, 2021) |
| "l-carnitine (LC) is a co-factor in fatty acid metabolism; its role with respect to aortic stiffness (AS) associated with chronic kidney disease (CKD) was unclear." | 1.56 | Association of Low Serum l-Carnitine Levels with Aortic Stiffness in Patients with Non-Dialysis Chronic Kidney Disease. ( Hsieh, YJ; Hsu, BG; Kuo, CH; Lai, YH; Lin, YL; Tsai, JP; Wang, CH, 2020) |
| "Carnitine measurements were not significantly different between the hemodialysis and peritoneal dialysis groups." | 1.43 | Absolute and Relative Carnitine Deficiency in Patients on Hemodialysis and Peritoneal Dialysis. ( Esmaeeli, M; Ghaneh Sherbaf, F; Horri, M; Jahanshahi, S; Moeenolroayaa, G; Mottaghi Moghadam Shahri, H; Naseri, M; Pour Hasan, M; Rasoli, Z; Salemian, F, 2016) |
| "l-Carnitine treatment of CKD rats significantly reduced serum creatinine and BUN, attenuated renal hypertrophy and decreased renal tissue damage." | 1.43 | l-Carnitine improves cognitive and renal functions in a rat model of chronic kidney disease. ( Abu Ahmad, N; Aga-Mizrachi, S; Armaly, Z; Avital, A; Berman, S; Jabour, A; Mosenego-Ornan, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 19 (61.29) | 24.3611 |
| 2020's | 10 (32.26) | 2.80 |
| Authors | Studies |
|---|---|
| Hamedi-Kalajahi, F | 2 |
| Imani, H | 2 |
| Mojtahedi, S | 1 |
| Shabbidar, S | 2 |
| Xu, P | 1 |
| Chen, C | 1 |
| Zhang, Y | 2 |
| Dzieciatkowska, M | 1 |
| Brown, BC | 1 |
| Zhang, W | 1 |
| Xie, T | 1 |
| Abdulmalik, O | 1 |
| Song, A | 1 |
| Tong, C | 1 |
| Qi, H | 1 |
| Roach, R | 1 |
| Kellems, RE | 1 |
| D'Alessandro, A | 1 |
| Xia, Y | 1 |
| Nishioka, N | 2 |
| Luo, Y | 2 |
| Taniguchi, T | 2 |
| Ohnishi, T | 2 |
| Kimachi, M | 2 |
| Ng, RC | 2 |
| Watanabe, N | 2 |
| Shimizu, S | 1 |
| Takashima, H | 1 |
| Tei, R | 1 |
| Furukawa, T | 1 |
| Okamura, M | 1 |
| Kitai, M | 1 |
| Nagura, C | 1 |
| Maruyama, T | 1 |
| Higuchi, T | 1 |
| Abe, M | 1 |
| Armaly, Z | 3 |
| Artol, S | 1 |
| Jabbour, AR | 1 |
| Saffouri, A | 1 |
| Habashi, N | 1 |
| Abd Elkadir, A | 1 |
| Ghattas, N | 1 |
| Farah, R | 1 |
| Kinaneh, S | 1 |
| Nseir, W | 1 |
| Yano, J | 1 |
| Ito, S | 1 |
| Kodama, G | 1 |
| Nakayama, Y | 1 |
| Kaida, Y | 1 |
| Yokota, Y | 1 |
| Kinoshita, Y | 1 |
| Tashiro, K | 1 |
| Fukami, K | 1 |
| Guo, F | 1 |
| Dai, Q | 1 |
| Zeng, X | 1 |
| Liu, Y | 1 |
| Tan, Z | 1 |
| Zhang, H | 1 |
| Ouyang, D | 1 |
| Hsieh, YJ | 1 |
| Hsu, BG | 1 |
| Lai, YH | 1 |
| Wang, CH | 1 |
| Lin, YL | 1 |
| Kuo, CH | 1 |
| Tsai, JP | 1 |
| Chen, YC | 1 |
| Cheng, CY | 1 |
| Liu, CT | 1 |
| Sue, YM | 1 |
| Chen, TH | 1 |
| Hsu, YH | 1 |
| Huang, NJ | 1 |
| Chen, CH | 1 |
| Daimon, S | 1 |
| Yasuda, M | 1 |
| Nishitani, M | 1 |
| Zhu, Y | 1 |
| Xue, C | 1 |
| Ou, J | 1 |
| Xie, Z | 1 |
| Deng, J | 1 |
| Zarezadeh, M | 1 |
| Mojtahedi, SY | 1 |
| Fahimi, D | 1 |
| Xu, KY | 1 |
| Xia, GH | 1 |
| Lu, JQ | 1 |
| Chen, MX | 1 |
| Zhen, X | 1 |
| Wang, S | 1 |
| You, C | 1 |
| Nie, J | 1 |
| Zhou, HW | 1 |
| Yin, J | 1 |
| Fernandez-Prado, R | 1 |
| Esteras, R | 1 |
| Perez-Gomez, MV | 1 |
| Gracia-Iguacel, C | 1 |
| Gonzalez-Parra, E | 1 |
| Sanz, AB | 1 |
| Ortiz, A | 1 |
| Sanchez-Niño, MD | 1 |
| Elmariah, S | 1 |
| Farrell, LA | 1 |
| Furman, D | 1 |
| Lindman, BR | 1 |
| Shi, X | 1 |
| Morningstar, JE | 1 |
| Rhee, EP | 1 |
| Gerszten, RE | 1 |
| Mercadal, L | 1 |
| Tezenas du Montcel, S | 1 |
| Chonchol, MB | 1 |
| Debure, A | 1 |
| Depreneuf, H | 1 |
| Servais, A | 1 |
| Bassilios, N | 1 |
| Assogba, U | 1 |
| Allouache, M | 1 |
| Prié, D | 1 |
| Hall, JA | 1 |
| Fritsch, DA | 1 |
| Jewell, DE | 1 |
| Burris, PA | 1 |
| Gross, KL | 1 |
| Nemati, A | 1 |
| Moghadam, RA | 1 |
| Mazani, M | 1 |
| Darvishi, A | 1 |
| Chen, DQ | 1 |
| Cao, G | 1 |
| Chen, H | 1 |
| Argyopoulos, CP | 1 |
| Yu, H | 1 |
| Su, W | 1 |
| Chen, L | 1 |
| Samuels, DC | 1 |
| Zhuang, S | 1 |
| Bayliss, GP | 1 |
| Zhao, S | 1 |
| Yu, XY | 1 |
| Vaziri, ND | 1 |
| Wang, M | 1 |
| Liu, D | 1 |
| Mao, JR | 1 |
| Ma, SX | 1 |
| Zhao, J | 1 |
| Shang, YQ | 1 |
| Kang, H | 1 |
| Ye, F | 1 |
| Cheng, XH | 1 |
| Li, XR | 1 |
| Zhang, L | 1 |
| Meng, MX | 1 |
| Guo, Y | 1 |
| Zhao, YY | 1 |
| Kordalewska, M | 1 |
| Macioszek, S | 1 |
| Wawrzyniak, R | 1 |
| Sikorska-Wiśniewska, M | 1 |
| Śledziński, T | 1 |
| Chmielewski, M | 1 |
| Mika, A | 1 |
| Markuszewski, MJ | 1 |
| Gessner, A | 1 |
| Mieth, M | 1 |
| Auge, D | 1 |
| Chafai, A | 1 |
| Müller, F | 1 |
| Fromm, MF | 1 |
| Maas, R | 1 |
| Moraes, C | 1 |
| Fouque, D | 1 |
| Amaral, AC | 1 |
| Mafra, D | 1 |
| Abd El Qader, A | 1 |
| Jabbour, A | 1 |
| Hassan, K | 1 |
| Ramadan, R | 1 |
| Bowirrat, A | 1 |
| Bisharat, B | 1 |
| Naseri, M | 1 |
| Mottaghi Moghadam Shahri, H | 1 |
| Horri, M | 1 |
| Esmaeeli, M | 1 |
| Ghaneh Sherbaf, F | 1 |
| Jahanshahi, S | 1 |
| Moeenolroayaa, G | 1 |
| Rasoli, Z | 1 |
| Salemian, F | 1 |
| Pour Hasan, M | 1 |
| Abu Ahmad, N | 1 |
| Berman, S | 1 |
| Jabour, A | 1 |
| Aga-Mizrachi, S | 1 |
| Mosenego-Ornan, E | 1 |
| Avital, A | 1 |
| Davies, M | 1 |
| Hocher, B | 1 |
| Adamski, J | 2 |
| Goek, ON | 1 |
| Döring, A | 1 |
| Gieger, C | 1 |
| Heier, M | 1 |
| Koenig, W | 1 |
| Prehn, C | 1 |
| Römisch-Margl, W | 1 |
| Wang-Sattler, R | 1 |
| Illig, T | 1 |
| Suhre, K | 1 |
| Sekula, P | 1 |
| Zhai, G | 1 |
| Köttgen, A | 1 |
| Meisinger, C | 1 |
| Reuter, SE | 1 |
| Evans, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Hemodialysis on Plasma Carnitine Levels in Patients With End Stage Renal Disease[NCT05817799] | Phase 2/Phase 3 | 83 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | ||
| Washed Microbiota Transplantation (WMT) for Chronic Kidney Disease (CKD): a Open Label, Multicenter Trial[NCT05838118] | 100 participants (Anticipated) | Interventional | 2023-04-20 | Recruiting | |||
| Early Administration of L-carnitine in Hemodialysis Patients: Double Blind Randomized Trial Versus Placebo[NCT00322322] | Phase 3 | 110 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease[NCT05719714] | Phase 1/Phase 2 | 60 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting | ||
| Effects of Carnitine on Oxidative Stress and Inflammatory Responses to Intravenous Iron Administration to Patients With CKD: Impact of Haptoglobin Genotype[NCT02312414] | 25 participants (Anticipated) | Interventional | 2014-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for carnitine and Chronic Kidney Diseases
| Article | Year |
|---|---|
Carnitine supplements for people with chronic kidney disease requiring dialysis.
Topics: Carnitine; Humans; Renal Insufficiency, Chronic | 2022 |
Carnitine supplements for people with chronic kidney disease requiring dialysis.
Topics: Carnitine; Humans; Renal Insufficiency, Chronic | 2022 |
Carnitine supplements for people with chronic kidney disease requiring dialysis.
Topics: Carnitine; Humans; Renal Insufficiency, Chronic | 2022 |
Carnitine supplements for people with chronic kidney disease requiring dialysis.
Topics: Carnitine; Humans; Renal Insufficiency, Chronic | 2022 |
Effect of L-carnitine supplementation on renal anemia in patients on hemodialysis: a meta-analysis.
Topics: Anemia; Carnitine; Dietary Supplements; Humans; Renal Dialysis; Renal Insufficiency, Chronic | 2021 |
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines | 2017 |
Trimethylamine N-Oxide From Gut Microbiota in Chronic Kidney Disease Patients: Focus on Diet.
Topics: Animals; Cardiovascular Diseases; Carnitine; Choline; Diet, Protein-Restricted; Disease Models, Anim | 2015 |
Veterinary clinical nutrition: success stories: an overview.
Topics: Animal Nutritional Physiological Phenomena; Animals; Calculi; Cardiomyopathies; Cardiomyopathy, Dila | 2016 |
Metabolomics for clinical use and research in chronic kidney disease.
Topics: Arginine; Biomarkers; Biomedical Research; Carnitine; Diabetes Mellitus; Humans; Lipid Metabolism; M | 2017 |
6 trials available for carnitine and Chronic Kidney Diseases
| Article | Year |
|---|---|
Effect of L-Carnitine Supplementation on Inflammatory Markers and Serum Glucose in Hemodialysis Children: A Randomized, Placebo-Controlled Clinical Trial.
Topics: Adolescent; Albumins; Biomarkers; Blood Glucose; C-Reactive Protein; Carnitine; Child; Dietary Suppl | 2022 |
Impact of pretreatment with carnitine and tadalafil on contrast-induced nephropathy in CKD patients.
Topics: Aged; Carnitine; Cross-Over Studies; Female; Haptoglobins; Humans; Kidney Diseases; Male; Phosphodie | 2019 |
Effect of L-carnitine supplementation on lipid profile and apolipoproteins in children on hemodialysis: a randomized placebo-controlled clinical trial.
Topics: Adolescent; Apolipoproteins; Carnitine; Child; Dietary Supplements; Humans; Iran; Lipids; Renal Dial | 2021 |
Effects of L-Carnitine on Mineral Metabolism in the Multicentre, Randomized, Double Blind, Placebo-Controlled CARNIDIAL Trial.
Topics: Aged; Calcification, Physiologic; Calcium; Carnitine; Chronic Kidney Disease-Mineral and Bone Disord | 2018 |
Effect of L-carnitine and conjugated linoleic acid supplements on haemoglobin levels and haptoglobin genotype in chronic kidney disease.
Topics: Adult; Anemia; C-Reactive Protein; Carnitine; Dietary Supplements; Ferritins; Genotype; Haptoglobins | 2019 |
Effects of carnitine on oxidative stress response to intravenous iron administration to patients with CKD: impact of haptoglobin phenotype.
Topics: Acute-Phase Proteins; Advanced Oxidation Protein Products; Aged; Anemia, Iron-Deficiency; C-Reactive | 2015 |
19 other studies available for carnitine and Chronic Kidney Diseases
| Article | Year |
|---|---|
Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis.
Topics: Animals; Carnitine; Erythrocytes; Homeostasis; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Su | 2022 |
Prevalence of Carnitine Deficiency and Decreased Carnitine Levels in Patients on Peritoneal Dialysis.
Topics: Aged; Carnitine; Female; Humans; Male; Middle Aged; Peritoneal Dialysis; Renal Insufficiency, Chroni | 2019 |
Kinetics of Serum Carnitine Fractions in Patients with Chronic Kidney Disease Not on Dialysis.
Topics: Adult; Aged; Amino Acids; Carnitine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Fail | 2021 |
Renal function is associated with plasma trimethylamine-N-oxide, choline, L-carnitine and betaine: a pilot study.
Topics: Betaine; Biomarkers; Carnitine; Choline; Female; Glomerular Filtration Rate; Humans; Kidney; Male; M | 2021 |
Association of Low Serum l-Carnitine Levels with Aortic Stiffness in Patients with Non-Dialysis Chronic Kidney Disease.
Topics: Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Body Height; Body Mass | 2020 |
Combined protective effects of oligo-fucoidan, fucoxanthin, and L-carnitine on the kidneys of chronic kidney disease mice.
Topics: Animals; Apoptosis; Biomarkers; Carnitine; Cell Line; Disease Models, Animal; Drug Therapy, Combinat | 2021 |
Serum carnitine concentration and the acyl to free carnitine ratio in nondialysis chronic kidney disease and hemodialysis patients.
Topics: Aged; Carnitine; Female; Humans; Male; Middle Aged; Renal Dialysis; Renal Insufficiency, Chronic | 2022 |
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis; | 2017 |
Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Topics: Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Carnitine; Choline; Diabetes Complications; Fe | 2018 |
Cats with IRIS stage 1 and 2 chronic kidney disease maintain body weight and lean muscle mass when fed food having increased caloric density, and enhanced concentrations of carnitine and essential amino acids.
Topics: Amino Acids, Essential; Animals; Body Weight; Carnitine; Cat Diseases; Cats; Diet; Energy Intake; Fe | 2019 |
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disea | 2019 |
Multiplatform metabolomics provides insight into the molecular basis of chronic kidney disease.
Topics: Adult; Aged; Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid; Clus | 2019 |
Establishment of reference values for the lysine acetylation marker N
Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; | 2019 |
Absolute and Relative Carnitine Deficiency in Patients on Hemodialysis and Peritoneal Dialysis.
Topics: Adolescent; Blood Urea Nitrogen; Carnitine; Child; Female; Humans; Male; Peritoneal Dialysis, Contin | 2016 |
l-Carnitine improves cognitive and renal functions in a rat model of chronic kidney disease.
Topics: Animals; Avoidance Learning; Blood Urea Nitrogen; Carnitine; Cognition; Creatinine; Disease Models, | 2016 |
Serum metabolite concentrations and decreased GFR in the general population.
Topics: Carnitine; Creatinine; Cross-Sectional Studies; Cystatin C; Female; Glomerular Filtration Rate; Huma | 2012 |
What is the value of L-carnitine level determination for carnitine supplementation in hemodialysis patients?
Topics: Carnitine; Humans; Renal Dialysis; Renal Insufficiency, Chronic | 2013 |
II. Clinical practice guidelines and clinical practice recommendations for anemia in chronic kidney disease in adults.
Topics: Adult; Androgens; Anemia; Ascorbic Acid; Blood Cell Count; Blood Transfusion; Carnitine; Contraindic | 2006 |
III. Clinical practice recommendations for anemia in chronic kidney disease in children.
Topics: Adolescent; Androgens; Anemia; Ascorbic Acid; Blood Cell Count; Blood Transfusion; Carnitine; Child; | 2006 |