Page last updated: 2024-10-16

carnitine and Chronic Hepatitis B

carnitine has been researched along with Chronic Hepatitis B in 8 studies

Research Excerpts

ExcerptRelevanceReference
"Treatment-naïve chronic hepatitis B patients receiving besifovir 90 mg (n=31), 150 mg (n=28) and entecavir 0."9.20Two-year treatment outcome of chronic hepatitis B infection treated with besifovir vs. entecavir: results from a multicentre study. ( Ahn, SH; Cho, M; Han, KH; Kim, JA; Kweon, YO; Lai, CL; Lee, J; Lee, JW; Lee, KS; Park, NH; Sohn, JH; Um, SH; Yoon, SK; Yuen, MF, 2015)
" The purpose of this study is to identify the efficacy and safety of carnitine from entecavir combination therapy in Alanine aminotransferase (ALT) elevated Chronic Hepatitis B (CHB) patients."9.17Efficacy and safety of entecavir plus carnitine complex (GODEX®) compared to entecavir monotherapy in patient with ALT elevated chronic hepatitis B: randomized, multicenter open-label trials. The GOAL study. ( Bae, SH; Baek, YH; Cheong, JY; Cho, SW; Cho, YK; Choi, JY; Han, SY; Heo, J; Hwang, SG; Jun, DW; Jung, YJ; Kim, BI; Kim, HJ; Kim, HY; Kim, JK; Kim, SH; Kim, TY; Kim, W; Kwon, YO; Lee, BS; Lee, KS; Lee, YS; Lim, YS; Paik, YH; Park, SY; Rim, KS; Sohn, JH; Woo, HY, 2013)
"The outcome of hepatitis B virus (HBV) infection is significantly affected by host immune response; herein, we aim to dissect the effect of L-carnitine (L-Cn) on germinal center (GC)-related immune cells and the influence on the prognosis of HBV infection."8.12Hepatocyte-Derived L-Carnitine Restricts Hepatitis B Surface Antigen Loss Through an Immunosuppressive Effect on Germinal Center-Related Immune Cells. ( Chen, C; Fu, X; Gu, S; Guo, L; Hou, J; Li, X; Li, Y; Sun, J; Tang, L; Wang, W; Wen, C; Ye, G; Zhong, S; Zhou, Y, 2022)
"Carnitine status of children with chronic hepatitis B is not yet clear."7.72Plasma and liver carnitine levels of children with chronic hepatitis B. ( Selimoğlu, MA; Yağci, RV, 2004)
"Persistent antigen exposure during chronic hepatitis B infection leads to exhausted immune responses, thus impeding viral control."5.62High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection. ( Chen, C; Chen, H; Fu, X; Gu, S; Hou, J; Jiang, D; Li, X; Li, Y; Tang, L; Ye, G; Zhong, S, 2021)
"Treatment-naïve chronic hepatitis B patients receiving besifovir 90 mg (n=31), 150 mg (n=28) and entecavir 0."5.20Two-year treatment outcome of chronic hepatitis B infection treated with besifovir vs. entecavir: results from a multicentre study. ( Ahn, SH; Cho, M; Han, KH; Kim, JA; Kweon, YO; Lai, CL; Lee, J; Lee, JW; Lee, KS; Park, NH; Sohn, JH; Um, SH; Yoon, SK; Yuen, MF, 2015)
" The purpose of this study is to identify the efficacy and safety of carnitine from entecavir combination therapy in Alanine aminotransferase (ALT) elevated Chronic Hepatitis B (CHB) patients."5.17Efficacy and safety of entecavir plus carnitine complex (GODEX®) compared to entecavir monotherapy in patient with ALT elevated chronic hepatitis B: randomized, multicenter open-label trials. The GOAL study. ( Bae, SH; Baek, YH; Cheong, JY; Cho, SW; Cho, YK; Choi, JY; Han, SY; Heo, J; Hwang, SG; Jun, DW; Jung, YJ; Kim, BI; Kim, HJ; Kim, HY; Kim, JK; Kim, SH; Kim, TY; Kim, W; Kwon, YO; Lee, BS; Lee, KS; Lee, YS; Lim, YS; Paik, YH; Park, SY; Rim, KS; Sohn, JH; Woo, HY, 2013)
"The outcome of hepatitis B virus (HBV) infection is significantly affected by host immune response; herein, we aim to dissect the effect of L-carnitine (L-Cn) on germinal center (GC)-related immune cells and the influence on the prognosis of HBV infection."4.12Hepatocyte-Derived L-Carnitine Restricts Hepatitis B Surface Antigen Loss Through an Immunosuppressive Effect on Germinal Center-Related Immune Cells. ( Chen, C; Fu, X; Gu, S; Guo, L; Hou, J; Li, X; Li, Y; Sun, J; Tang, L; Wang, W; Wen, C; Ye, G; Zhong, S; Zhou, Y, 2022)
"In chronic hepatitis B patients treated with peginterferon and adefovir, we identified strong associations of SLC16A9 gene variation and carnitine levels with HBsAg loss."3.80HBsAg loss in patients treated with peginterferon alfa-2a and adefovir is associated with SLC16A9 gene variation and lower plasma carnitine levels. ( Chin, DJ; de Niet, A; Jansen, L; Kootstra, NA; Lopatin, U; Plat-Sinnige, MJ; Reesink, HW; Stelma, F; Takkenberg, RB; van Dort, KA; van Iperen, EP; Zwinderman, AH, 2014)
"Carnitine status of children with chronic hepatitis B is not yet clear."3.72Plasma and liver carnitine levels of children with chronic hepatitis B. ( Selimoğlu, MA; Yağci, RV, 2004)
"Persistent antigen exposure during chronic hepatitis B infection leads to exhausted immune responses, thus impeding viral control."1.62High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection. ( Chen, C; Chen, H; Fu, X; Gu, S; Hou, J; Jiang, D; Li, X; Li, Y; Tang, L; Ye, G; Zhong, S, 2021)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Gu, S2
Wang, W1
Ye, G2
Chen, C2
Zhou, Y1
Guo, L1
Zhong, S2
Li, X2
Fu, X2
Wen, C1
Tang, L2
Sun, J1
Hou, J2
Li, Y2
Chen, H1
Jiang, D1
Jun, DW1
Kim, BI1
Cho, YK1
Kim, HJ1
Kwon, YO1
Park, SY1
Han, SY1
Baek, YH1
Jung, YJ1
Kim, HY1
Kim, W1
Heo, J1
Woo, HY1
Hwang, SG1
Rim, KS1
Choi, JY1
Bae, SH1
Lee, YS1
Lim, YS1
Cheong, JY1
Cho, SW1
Lee, BS1
Kim, SH1
Sohn, JH3
Kim, TY1
Paik, YH1
Kim, JK1
Lee, KS3
Lai, CL2
Ahn, SH2
Um, SH2
Cho, M2
Yoon, SK2
Lee, JW2
Park, NH2
Kweon, YO2
Lee, J2
Kim, JA2
Han, KH2
Yuen, MF2
Jansen, L1
de Niet, A1
Stelma, F1
van Iperen, EP1
van Dort, KA1
Plat-Sinnige, MJ1
Takkenberg, RB1
Chin, DJ1
Zwinderman, AH1
Lopatin, U1
Kootstra, NA1
Reesink, HW1
Selimoğlu, MA1
Yağci, RV1
Eskandari, GH1
Polat, G1
Tamer, L1
Ersöz, G1
Atik, U1

Trials

3 trials available for carnitine and Chronic Hepatitis B

ArticleYear
Efficacy and safety of entecavir plus carnitine complex (GODEX®) compared to entecavir monotherapy in patient with ALT elevated chronic hepatitis B: randomized, multicenter open-label trials. The GOAL study.
    Clinical and molecular hepatology, 2013, Volume: 19, Issue:2

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Carnitine; DNA, Viral; Drug Therapy, Combination; Enz

2013
Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B.
    Gut, 2014, Volume: 63, Issue:6

    Topics: Adult; Alanine Transaminase; Antibodies, Viral; Antiviral Agents; Asian People; Carnitine; DNA, Vira

2014
Two-year treatment outcome of chronic hepatitis B infection treated with besifovir vs. entecavir: results from a multicentre study.
    Journal of hepatology, 2015, Volume: 62, Issue:3

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Carnitine; DNA, Viral; Female; Guanine; Hepatitis B e

2015

Other Studies

5 other studies available for carnitine and Chronic Hepatitis B

ArticleYear
Hepatocyte-Derived L-Carnitine Restricts Hepatitis B Surface Antigen Loss Through an Immunosuppressive Effect on Germinal Center-Related Immune Cells.
    The Journal of infectious diseases, 2022, 06-01, Volume: 225, Issue:11

    Topics: Animals; Carnitine; Germinal Center; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; H

2022
High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase; CD4

2021
HBsAg loss in patients treated with peginterferon alfa-2a and adefovir is associated with SLC16A9 gene variation and lower plasma carnitine levels.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Adenine; Adult; Antiviral Agents; Carnitine; CD8-Positive T-Lymphocytes; Drug Therapy, Combination;

2014
Plasma and liver carnitine levels of children with chronic hepatitis B.
    Journal of clinical gastroenterology, 2004, Volume: 38, Issue:2

    Topics: Adolescent; Antiviral Agents; Carnitine; Child; Child, Preschool; Drug Therapy, Combination; Female;

2004
Serum L-carnitine levels and lipoprotein compositions in chronic viral hepatitis patients.
    Clinical biochemistry, 2001, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Choles

2001