carnitine has been researched along with Chronic Fatigue and Immune Dysfunction Syndrome in 22 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The serum concentrations of total, free and acylcarnitine were compared in 25 patients with multiple sclerosis (MS) and among age- and sex-matched normal controls by the new enzymatic cycling method in order to clarify whether the fatigue in MS might be due to possible carnitine-related fatty acid metabolic abnormalities in the mitochondria of skeletal muscles." | 7.69 | Serum carnitine and disabling fatigue in multiple sclerosis. ( Fukazawa, T; Hamada, T; Kikuchi, S; Sasaki, H; Tashiro, K, 1996) |
| "Patients with chronic fatigue syndrome (CFS) complain of muscle pain and impaired exercise tolerance." | 5.31 | Normal carnitine levels in patients with chronic fatigue syndrome. ( Bleijenberg, G; Elving, LD; Janssen, AJ; Soetekouw, PM; van der Meer, JW; van der Veen, Y; Vreken, P; Wevers, RA, 2000) |
| "The serum concentrations of total, free and acylcarnitine were compared in 25 patients with multiple sclerosis (MS) and among age- and sex-matched normal controls by the new enzymatic cycling method in order to clarify whether the fatigue in MS might be due to possible carnitine-related fatty acid metabolic abnormalities in the mitochondria of skeletal muscles." | 3.69 | Serum carnitine and disabling fatigue in multiple sclerosis. ( Fukazawa, T; Hamada, T; Kikuchi, S; Sasaki, H; Tashiro, K, 1996) |
| "L-Carnitine is a safe and very well tolerated medicine which improves the clinical status of CFS patients." | 2.68 | Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. ( Plioplys, AV; Plioplys, S, 1997) |
| "Many patients with chronic fatigue syndrome(CFS) fulfill the criteria of FMS and represent one end of a spectrum of presentation." | 2.40 | [Fibromyalgia syndrome]. ( Matsumoto, Y, 1999) |
| "Myalgic encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI) share many symptoms of fatigue, pain, and cognitive dysfunction that are not relieved by rest." | 1.62 | Exercise modifies glutamate and other metabolic biomarkers in cerebrospinal fluid from Gulf War Illness and Myalgic encephalomyelitis / Chronic Fatigue Syndrome. ( Baraniuk, JN; Cheema, A; Kern, G; Narayan, V, 2021) |
| "The underlying aetiology of chronic fatigue syndrome is currently unknown; however, in the light of carnitine's critical role in mitochondrial energy production, it has been suggested that chronic fatigue syndrome may be associated with altered carnitine homeostasis." | 1.37 | Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity. ( Evans, AM; Reuter, SE, 2011) |
| "Patients with chronic fatigue syndrome (CFS) complain of muscle pain and impaired exercise tolerance." | 1.31 | Normal carnitine levels in patients with chronic fatigue syndrome. ( Bleijenberg, G; Elving, LD; Janssen, AJ; Soetekouw, PM; van der Meer, JW; van der Veen, Y; Vreken, P; Wevers, RA, 2000) |
| "As carnitine has an important role in energy production and modulation of the intramitochondrial coenzyme A (CoA)/acyl-CoA ratio in the skeletal muscle, this deficiency might induce an energy deficit and/or abnormality of the intramitochondrial condition in the skeletal muscle, thus resulting in general fatigue, myalgia, muscle weakness, and postexertional malaise in patients with CFS." | 1.29 | Acylcarnitine deficiency in chronic fatigue syndrome. ( Kitani, T; Kuratsune, H; Misaki, H; Tagawa, S; Takahashi, M; Yamaguti, K, 1994) |
| "Patients with chronic fatigue syndrome (CFS) suffer from disabling physical and mental fatigue." | 1.29 | Electron-microscopic investigation of muscle mitochondria in chronic fatigue syndrome. ( Plioplys, AV; Plioplys, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (45.45) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Baraniuk, JN | 1 |
| Kern, G | 1 |
| Narayan, V | 1 |
| Cheema, A | 1 |
| Nicolson, GL | 1 |
| Horiuchi, M | 1 |
| Nakakuma, M | 1 |
| Arimura, E | 1 |
| Ushikai, M | 1 |
| Yoshida, G | 1 |
| Reuter, SE | 1 |
| Evans, AM | 1 |
| Laffon-Pioger, M | 1 |
| Rocher, F | 1 |
| Caruba, C | 1 |
| Cohen, M | 1 |
| Thomas, P | 1 |
| Lebrun, C | 1 |
| Jones, MG | 1 |
| Goodwin, CS | 1 |
| Amjad, S | 1 |
| Chalmers, RA | 1 |
| Malaguarnera, M | 1 |
| Di Mauro, A | 1 |
| Gargante, PM | 1 |
| Rampello, L | 1 |
| Miwa, S | 1 |
| Takikawa, O | 1 |
| Famularo, G | 1 |
| De Simone, C | 1 |
| Kuratsune, H | 3 |
| Yamaguti, K | 2 |
| Takahashi, M | 2 |
| Misaki, H | 1 |
| Tagawa, S | 1 |
| Kitani, T | 3 |
| Plioplys, AV | 3 |
| Plioplys, S | 3 |
| Grant, JE | 1 |
| Veldee, MS | 1 |
| Buchwald, D | 1 |
| Fukazawa, T | 1 |
| Sasaki, H | 1 |
| Kikuchi, S | 1 |
| Hamada, T | 1 |
| Tashiro, K | 1 |
| Lindh, G | 1 |
| Evengard, B | 1 |
| Machii, T | 1 |
| Matsumura, K | 1 |
| Takaishi, J | 1 |
| Kawata, S | 1 |
| Långström, B | 1 |
| Kanakura, Y | 1 |
| Watanabe, Y | 1 |
| Matsumoto, Y | 1 |
| Soetekouw, PM | 1 |
| Wevers, RA | 1 |
| Vreken, P | 1 |
| Elving, LD | 1 |
| Janssen, AJ | 1 |
| van der Veen, Y | 1 |
| Bleijenberg, G | 1 |
| van der Meer, JW | 1 |
| Masuda, A | 1 |
| Nakayama, T | 1 |
| Yamanaka, T | 1 |
| Hatsutanmaru, K | 1 |
| Tei, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised, Double Blinded Cross-over Study Comparing the Efficacy of L-carnitine Versus Placebo in the Treatment of Fatigue in Multiple Sclerosis[NCT01149525] | Phase 3 | 59 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for carnitine and Chronic Fatigue and Immune Dysfunction Syndrome
| Article | Year |
|---|---|
[Experimental Approach to Analysis of the Relationship between Food Environments and Lifestyle-Related Diseases, Including Cardiac Hypertrophy, Fatty Liver, and Fatigue Symptoms].
Topics: Animals; Beriberi; Cardiomegaly; Carnitine; Disease Models, Animal; Fatigue Syndrome, Chronic; Fatty | 2015 |
[Chronic fatigue syndrome and neurotransmitters].
Topics: Animals; Carnitine; Fatigue Syndrome, Chronic; Glutamates; Humans; Membrane Proteins; Neurotransmitt | 2007 |
[Fibromyalgia syndrome].
Topics: Biomarkers; Carnitine; Diagnosis, Differential; Fatigue; Fatigue Syndrome, Chronic; Fibromyalgia; Hu | 1999 |
[Chronic fatigue syndrome].
Topics: Carnitine; Diagnosis, Differential; Endocrine System Diseases; Fatigue Syndrome, Chronic; Humans; Im | 2000 |
2 trials available for carnitine and Chronic Fatigue and Immune Dysfunction Syndrome
| Article | Year |
|---|---|
Carnitine serum levels and levocarnitine administration in multiple sclerosis patients treated with natalizumab.
Topics: Antibodies, Monoclonal, Humanized; Carnitine; Cohort Studies; Fatigue Syndrome, Chronic; Female; Hum | 2011 |
Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome.
Topics: Amantadine; Antiviral Agents; Carnitine; Cross-Over Studies; Fatigue Syndrome, Chronic; Humans; Neur | 1997 |
Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome.
Topics: Amantadine; Antiviral Agents; Carnitine; Cross-Over Studies; Fatigue Syndrome, Chronic; Humans; Neur | 1997 |
Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome.
Topics: Amantadine; Antiviral Agents; Carnitine; Cross-Over Studies; Fatigue Syndrome, Chronic; Humans; Neur | 1997 |
Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome.
Topics: Amantadine; Antiviral Agents; Carnitine; Cross-Over Studies; Fatigue Syndrome, Chronic; Humans; Neur | 1997 |
16 other studies available for carnitine and Chronic Fatigue and Immune Dysfunction Syndrome
| Article | Year |
|---|---|
Exercise modifies glutamate and other metabolic biomarkers in cerebrospinal fluid from Gulf War Illness and Myalgic encephalomyelitis / Chronic Fatigue Syndrome.
Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Exercise Test; Fatigue Syndrome, Chronic; Female | 2021 |
Mitochondrial dysfunction and chronic disease: treatment with natural supplements.
Topics: Carnitine; Dietary Supplements; Fatigue Syndrome, Chronic; Humans; Mitochondrial Diseases; NAD; Thio | 2014 |
Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity.
Topics: Adult; Aged; Carnitine; Carnitine O-Palmitoyltransferase; Epidemiologic Methods; Fatigue Syndrome, C | 2011 |
L-carnitine.
Topics: Carnitine; Controlled Clinical Trials as Topic; Deficiency Diseases; Dietary Supplements; Double-Bli | 2004 |
Plasma and urinary carnitine and acylcarnitines in chronic fatigue syndrome.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Carnitine; Case-Control Studies; Depression; | 2005 |
L-carnitine reduces severity of physical and mental fatigue and improves daily activities in the elderly.
Topics: Activities of Daily Living; Aged, 80 and over; Carnitine; Fatigue Syndrome, Chronic; Follow-Up Studi | 2006 |
A new era for carnitine?
Topics: Acquired Immunodeficiency Syndrome; Carnitine; Fatigue Syndrome, Chronic; Humans; Shock, Septic | 1995 |
Acylcarnitine deficiency in chronic fatigue syndrome.
Topics: Acyl Coenzyme A; Carnitine; Coenzyme A; Energy Metabolism; Fatigue Syndrome, Chronic; Female; Humans | 1994 |
[Chronic fatigue syndrome].
Topics: Ascorbic Acid; Carnitine; Endocrine System Diseases; Fatigue Syndrome, Chronic; Humans; Killer Cells | 1993 |
Serum levels of carnitine in chronic fatigue syndrome: clinical correlates.
Topics: Adolescent; Adult; Aged; Carnitine; Fatigue Syndrome, Chronic; Female; Humans; Male; Middle Aged; Mi | 1995 |
Electron-microscopic investigation of muscle mitochondria in chronic fatigue syndrome.
Topics: Adolescent; Adult; Carnitine; Fatigue Syndrome, Chronic; Female; Humans; Lipid Metabolism; Male; Mat | 1995 |
Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome.
Topics: Acylation; Ascorbic Acid; Carnitine; Diet; Erythrocytes; Fatigue Syndrome, Chronic; Female; Food, Fo | 1996 |
Serum carnitine and disabling fatigue in multiple sclerosis.
Topics: Adult; Carnitine; Fatigue; Fatigue Syndrome, Chronic; Female; Humans; Male; Mitochondria, Muscle; Mu | 1996 |
Low levels of serum acylcarnitine in chronic fatigue syndrome and chronic hepatitis type C, but not seen in other diseases.
Topics: Acute Disease; Animals; Carnitine; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Fatigu | 1998 |
Normal carnitine levels in patients with chronic fatigue syndrome.
Topics: Adult; Carnitine; Case-Control Studies; Fatigue; Fatigue Syndrome, Chronic; Female; Humans; Middle A | 2000 |
Cognitive behavioral therapy and fasting therapy for a patient with chronic fatigue syndrome.
Topics: Adult; Carnitine; Cognitive Behavioral Therapy; Fasting; Fatigue Syndrome, Chronic; Humans; Killer C | 2001 |