carnitine has been researched along with Choline Deficiency in 21 studies
Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the study was to investigate the role of MMPs and their inhibitors (TIMPs), in the pathogenesis of choline deficiency-induced cardiomyopathy, and the way they are affected by carnitine supplementation." | 3.83 | Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine. ( Giannopoulou, I; Karkalousos, P; Kriebardis, A; Lazaris, A; Liapi, C; Panayiotides, I; Papavdi, A; Perelas, A; Strilakou, A, 2016) |
| "Choline is an essential nutrient, and choline deficiency has been associated with cardiovascular morbidity." | 3.80 | Carnitine modulates crucial myocardial adenosine triphosphatases and acetylcholinesterase enzyme activities in choline-deprived rats. ( Kalafatakis, KG; Karkalousos, PL; Koulouris, AV; Liapi, CA; Mourouzis, IS; Strilakou, AA; Stylianaki, AT; Tsakiris, ST, 2014) |
| "Previous reports in animals indicate that choline deficiency alters carnitine metabolism." | 3.69 | Restricting food intake does not exacerbate the effects of a choline-deficient diet on tissue carnitine concentrations in rats. ( Krasin, B; Sheard, NF, 1994) |
| "Choline is a conditionally essential nutrient in this population." | 2.67 | Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. ( Ament, ME; Buchman, AL; Dubin, M; Eckhert, CD; Gornbein, J; Jenden, D; Moukarzel, A; Rice, K; Roch, MH, 1992) |
| "Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disorder." | 1.56 | L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. ( Codella, R; Luzi, L; Mollica, G; Montesano, A; Senesi, P; Terruzzi, I; Vacante, F, 2020) |
| "The study investigates the effects of choline deficiency on myocardial performance in adult rats and the possible modifications after carnitine administration." | 1.39 | Heart dysfunction induced by choline-deficiency in adult rats: the protective role of L-carnitine. ( Douzis, ICh; Karkalousos, PL; Lazaris, AC; Liapi, CA; Mourouzis, IS; Pantos, CI; Perelas, AI; Strilakou, AA; Stylianaki, AT, 2013) |
| "Carnitine treatment increased the mRNA expression of carnitine palmitoyltransferase 1A and peroxisome proliferator-activated receptor-γ, and carnitine-lipoic acid further augmented the mRNA expression." | 1.37 | Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. ( Cho, WK; Choi, HS; Hahm, JS; Jang, KS; Jeon, HJ; Jun, DW; Jun, JH; Kim, HJ; Kwon, HJ; Lee, HL; Lee, KN; Lee, MH; Lee, OY; Yoon, BC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Mollica, G | 1 |
| Senesi, P | 1 |
| Codella, R | 1 |
| Vacante, F | 1 |
| Montesano, A | 1 |
| Luzi, L | 1 |
| Terruzzi, I | 1 |
| Strilakou, AA | 2 |
| Lazaris, AC | 1 |
| Perelas, AI | 1 |
| Mourouzis, IS | 2 |
| Douzis, ICh | 1 |
| Karkalousos, PL | 2 |
| Stylianaki, AT | 2 |
| Pantos, CI | 1 |
| Liapi, CA | 2 |
| Tsakiris, ST | 1 |
| Kalafatakis, KG | 1 |
| Koulouris, AV | 1 |
| Strilakou, A | 1 |
| Perelas, A | 1 |
| Lazaris, A | 1 |
| Papavdi, A | 1 |
| Karkalousos, P | 1 |
| Giannopoulou, I | 1 |
| Kriebardis, A | 1 |
| Panayiotides, I | 1 |
| Liapi, C | 1 |
| Jun, DW | 1 |
| Cho, WK | 1 |
| Jun, JH | 1 |
| Kwon, HJ | 1 |
| Jang, KS | 1 |
| Kim, HJ | 1 |
| Jeon, HJ | 1 |
| Lee, KN | 1 |
| Lee, HL | 1 |
| Lee, OY | 1 |
| Yoon, BC | 1 |
| Choi, HS | 1 |
| Hahm, JS | 1 |
| Lee, MH | 1 |
| FRITZ, IB | 2 |
| DUPONT, P | 1 |
| Corredor, C | 1 |
| Mansbach, C | 1 |
| Bressler, R | 1 |
| Jacob, RA | 1 |
| Pianalto, FS | 1 |
| Henning, SM | 1 |
| Zhang, JZ | 1 |
| Swendseid, ME | 1 |
| Sheard, NF | 1 |
| Krasin, B | 1 |
| Buchman, AL | 2 |
| Carter, AL | 1 |
| Frenkel, R | 1 |
| Tsai, AC | 2 |
| Romsos, DR | 2 |
| Leveille, GA | 2 |
| Dubin, M | 1 |
| Jenden, D | 1 |
| Moukarzel, A | 1 |
| Roch, MH | 1 |
| Rice, K | 1 |
| Gornbein, J | 1 |
| Ament, ME | 1 |
| Eckhert, CD | 1 |
| Rudman, D | 2 |
| Feller, A | 1 |
| Williams, PJ | 1 |
| Ketola, HG | 1 |
| Young, RJ | 1 |
| Seifter, E | 1 |
| Rettura, G | 1 |
| Jose, JM | 1 |
| Levenson, SM | 1 |
| Mehlman, MA | 1 |
| Therriault, DG | 1 |
| Tobin, RB | 1 |
2 reviews available for carnitine and Choline Deficiency
| Article | Year |
|---|---|
Nutrient deficiencies during total parenteral nutrition.
Topics: Adolescent; Adult; Aged; Animals; Biotin; Carnitine; Child; Choline Deficiency; Chromium; Copper; Cy | 1985 |
Choline deficiency and carnitine depletion.
Topics: Animals; Carnitine; Choline Deficiency; Fatty Acids; Oxidation-Reduction; Rats | 1968 |
2 trials available for carnitine and Choline Deficiency
| Article | Year |
|---|---|
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction.
Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; | 1995 |
Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients.
Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Choline; Choline Deficiency; Fat | 1992 |
17 other studies available for carnitine and Choline Deficiency
| Article | Year |
|---|---|
L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet.
Topics: Animals; Carnitine; Choline Deficiency; Diet; Dietary Supplements; Disease Models, Animal; Disease P | 2020 |
Heart dysfunction induced by choline-deficiency in adult rats: the protective role of L-carnitine.
Topics: Animals; Cardiotonic Agents; Carnitine; Choline Deficiency; Dietary Supplements; Edema, Cardiac; Fib | 2013 |
Carnitine modulates crucial myocardial adenosine triphosphatases and acetylcholinesterase enzyme activities in choline-deprived rats.
Topics: Acetylcholinesterase; Animals; Ca(2+) Mg(2+)-ATPase; Cardiotonic Agents; Carnitine; Choline; Choline | 2014 |
Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine.
Topics: Administration, Oral; Animals; Cardiomyopathies; Carnitine; Choline Deficiency; Disease Models, Anim | 2016 |
Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Carnitine; Carnitine O-Palmitoyltransferase; Choline Def | 2011 |
Effects of choline deficiency and carnitine on palmitic acid oxidation by rat liver homogenates.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Fatty Acids; Folic Acid; Lipid Metabolism; Liver; O | 1957 |
Ineffectiveness of carnitine as a choline substitute in the prevention of fatty livers of rats maintained on a choline-deficient diet.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Diet; Fatty Liver; Folic Acid; Rats; Vitamin B Comp | 1957 |
Carnitine depletion in the choline-deficient state.
Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Isotopes; Carnitine; Choline; Choline De | 1967 |
Restricting food intake does not exacerbate the effects of a choline-deficient diet on tissue carnitine concentrations in rats.
Topics: Animals; Body Weight; Carnitine; Choline; Choline Deficiency; Creatinine; Diet; Food Deprivation; Li | 1994 |
Relation between choline and carnitine homeostasis.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Homeostasis; Humans; Rats | 1997 |
The relationship of choline and carnitine in the choline deficient rat.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Ketone Bodies; Liver; Male; Muscles; Myocardium; Ra | 1978 |
Determination of carnitine turnover in choline-deficient and cold-exposed rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Carbon Radioisot | 1975 |
Evidence for deficiencies of conditionally essential nutrients during total parenteral nutrition.
Topics: Carnitine; Choline Deficiency; Cysteine; Deficiency Diseases; Humans; Parenteral Nutrition, Total; T | 1986 |
The need for dietary choline by young Japanese quail.
Topics: Animal Feed; Animals; Betaine; Carnitine; Choline; Choline Deficiency; Coturnix; Diet; Ethanolamines | 1973 |
Significance of dietary carnitine for growth and carnitine turnover in rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Carbon Radioisot | 1974 |
Inability of carnitine to promote growth of choline deficidnt chicks.
Topics: Animal Feed; Animals; Carnitine; Chickens; Choline Deficiency; Growth; Male; Poultry Diseases | 1970 |
Carnitine-14C metabolism in choline-deficient, alloxan-diabetic choline-deficient and insulin-treated rats.
Topics: Animals; Carbon Isotopes; Carnitine; Choline Deficiency; Chromatography, Paper; Diabetes Mellitus, E | 1971 |