Page last updated: 2024-10-16

carnitine and Cancer of Liver

carnitine has been researched along with Cancer of Liver in 28 studies

Research Excerpts

ExcerptRelevanceReference
"Longitudinal assessments of carnitine and fatigue in patients with hepatocellular carcinoma suggest that lenvatinib affects the carnitine system in patients undergoing lenvatinib therapy and that carnitine insufficiency increases fatigue."9.34Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma. ( Ando, H; Ikejima, K; Ishizuka, K; Kitagawa, R; Kokubu, S; Miyazaki, A; Nagahara, A; Okubo, H; Okubo, S; Saito, H; Shiina, S, 2020)
" Therefore, this study aimed to evaluate the effects of lenvatinib (LEN) on skeletal muscle volume and cardiac function in patients with hepatocellular carcinoma (HCC)."8.31Effects of Lenvatinib on Skeletal Muscle Volume and Cardiac Function in Patients with Hepatocellular Carcinoma. ( Amanuma, M; Daido, Y; Higai, K; Igarashi, Y; Kobayashi, K; Matsuda, T; Matsui, T; Matsukiyo, Y; Mohri, K; Momiyama, K; Mukozu, T; Nagai, H; Nagumo, H; Ogino, Y; Wakui, N; Watanabe, G; Yoshimine, N, 2023)
"Carnitine metabolism is thought to be negatively correlated with the progression of hepatocellular carcinoma (HCC) and the specific molecular mechanism is yet to be fully elucidated."8.12CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma. ( Chen, K; Lin, W; Liu, C; Lu, Y; Wang, H; Wang, J; Zhang, D; Zhang, Y; Zhao, L; Zhao, W; Zhou, Y, 2022)
"This study investigated the inhibitory effect of levocarnitine supplementation on sarcopenia progression in hepatocellular carcinoma (HCC) patients treated with lenvatinib."8.02Levocarnitine Supplementation Suppresses Lenvatinib-Related Sarcopenia in Hepatocellular Carcinoma Patients: Results of a Propensity Score Analysis. ( Ando, H; Ikejima, K; Nagahara, A; Nakadera, E; Okubo, H; Shiina, S, 2021)
" In this study, we measured the serum levels of 15 acylcarnitine species of various carbon chain lengths from 2 to 18 in 241 patients with biopsy-proven NAFLD, including 23 patients with hepatocellular carcinoma (HCC), and analyzed the relationship between serum acylcarnitine profile and NAFLD status."7.91Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma. ( Enooku, K; Fujiwara, N; Hoshida, Y; Koike, K; Kondo, M; Minami, T; Nakagawa, H; Shibahara, J; Tateishi, R, 2019)
" L-Carnitine is a vitamin-like substance and several reports have described the usefulness of L-carnitine supplementation in cases of cirrhosis, with confirmed effectiveness against refractory hepatic encephalopathy."7.81Usefulness of Levocarnitine and/or Branched-Chain Amino Acids during Invasive Treatment for Hepatocellular Carcinoma. ( Hasegawa, H; Ishihara, T; Iwasa, M; Kobayashi, Y; Mifuji-Moroka, R; Sekoguchi-Fujikawa, N; Sugimoto, R; Takei, Y; Tanaka, H; Yoshikawa, K, 2015)
"Persistent antigen exposure during chronic hepatitis B infection leads to exhausted immune responses, thus impeding viral control."5.62High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection. ( Chen, C; Chen, H; Fu, X; Gu, S; Hou, J; Jiang, D; Li, X; Li, Y; Tang, L; Ye, G; Zhong, S, 2021)
"Longitudinal assessments of carnitine and fatigue in patients with hepatocellular carcinoma suggest that lenvatinib affects the carnitine system in patients undergoing lenvatinib therapy and that carnitine insufficiency increases fatigue."5.34Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma. ( Ando, H; Ikejima, K; Ishizuka, K; Kitagawa, R; Kokubu, S; Miyazaki, A; Nagahara, A; Okubo, H; Okubo, S; Saito, H; Shiina, S, 2020)
" Therefore, this study aimed to evaluate the effects of lenvatinib (LEN) on skeletal muscle volume and cardiac function in patients with hepatocellular carcinoma (HCC)."4.31Effects of Lenvatinib on Skeletal Muscle Volume and Cardiac Function in Patients with Hepatocellular Carcinoma. ( Amanuma, M; Daido, Y; Higai, K; Igarashi, Y; Kobayashi, K; Matsuda, T; Matsui, T; Matsukiyo, Y; Mohri, K; Momiyama, K; Mukozu, T; Nagai, H; Nagumo, H; Ogino, Y; Wakui, N; Watanabe, G; Yoshimine, N, 2023)
"Carnitine metabolism is thought to be negatively correlated with the progression of hepatocellular carcinoma (HCC) and the specific molecular mechanism is yet to be fully elucidated."4.12CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma. ( Chen, K; Lin, W; Liu, C; Lu, Y; Wang, H; Wang, J; Zhang, D; Zhang, Y; Zhao, L; Zhao, W; Zhou, Y, 2022)
"This study investigated the inhibitory effect of levocarnitine supplementation on sarcopenia progression in hepatocellular carcinoma (HCC) patients treated with lenvatinib."4.02Levocarnitine Supplementation Suppresses Lenvatinib-Related Sarcopenia in Hepatocellular Carcinoma Patients: Results of a Propensity Score Analysis. ( Ando, H; Ikejima, K; Nagahara, A; Nakadera, E; Okubo, H; Shiina, S, 2021)
" In this study, we measured the serum levels of 15 acylcarnitine species of various carbon chain lengths from 2 to 18 in 241 patients with biopsy-proven NAFLD, including 23 patients with hepatocellular carcinoma (HCC), and analyzed the relationship between serum acylcarnitine profile and NAFLD status."3.91Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma. ( Enooku, K; Fujiwara, N; Hoshida, Y; Koike, K; Kondo, M; Minami, T; Nakagawa, H; Shibahara, J; Tateishi, R, 2019)
" L-Carnitine is a vitamin-like substance and several reports have described the usefulness of L-carnitine supplementation in cases of cirrhosis, with confirmed effectiveness against refractory hepatic encephalopathy."3.81Usefulness of Levocarnitine and/or Branched-Chain Amino Acids during Invasive Treatment for Hepatocellular Carcinoma. ( Hasegawa, H; Ishihara, T; Iwasa, M; Kobayashi, Y; Mifuji-Moroka, R; Sekoguchi-Fujikawa, N; Sugimoto, R; Takei, Y; Tanaka, H; Yoshikawa, K, 2015)
"It can be concluded that L-carnitine supplementation may be a good approach for a multi-targeted therapy for the treatment of cancer-related cachexia."3.78L-Carnitine: an adequate supplement for a multi-targeted anti-wasting therapy in cancer. ( Argilés, JM; Betancourt, A; Busquets, S; Capdevila, E; López-Soriano, FJ; Macciò, A; Madeddu, C; Mantovani, G; Marmonti, E; Orpí, M; Pin, F; Serpe, R; Toledo, M, 2012)
"Methods."2.80Effects of Oral L-Carnitine on Liver Functions after Transarterial Chemoembolization in Intermediate-Stage HCC Patients. ( Abdelaal, UM; Arafa, UA; Asai, A; Fukunishi, S; Hassan, A; Hassan, AT; Higuchi, K; Kassem, AM; Nakamura, K; Ohama, H; Sujishi, T; Tsuchimoto, Y; Tsuda, Y; Yokohama, K, 2015)
"Persistent antigen exposure during chronic hepatitis B infection leads to exhausted immune responses, thus impeding viral control."1.62High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection. ( Chen, C; Chen, H; Fu, X; Gu, S; Hou, J; Jiang, D; Li, X; Li, Y; Tang, L; Ye, G; Zhong, S, 2021)
"Correct staging of hepatocellular carcinoma (HCC) could help physicians to precisely select treatments for patients, such as surgery, chemotherapy, or their combination."1.48Dysregulated serum metabolites in staging of hepatocellular carcinoma. ( Chen, N; Chen, Y; Lou, B; Lv, J; Mao, W; Wang, P; Wang, W, 2018)
"Hepatocellular carcinoma has a poor prognosis due to its rapid development and early metastasis."1.39Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics. ( Gao, P; Huang, Q; Lu, X; Tan, Y; Wang, H; Xu, G; Ye, G; Yin, P, 2013)
" Therefore, we investigated whether long-term administration of L-carnitine could prevent hepatitis and subsequent hepatocellular carcinoma in Long-Evans Cinnamon rats that are often analyzed as a model of hepatocarcinogenesis."1.33L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria. ( Chang, B; Inoue, M; Nishiguchi, S; Nishikawa, M, 2005)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's4 (14.29)29.6817
2010's13 (46.43)24.3611
2020's10 (35.71)2.80

Authors

AuthorsStudies
Okubo, H2
Ando, H2
Nakadera, E1
Ikejima, K2
Shiina, S2
Nagahara, A2
Wang, J1
Zhou, Y1
Zhang, D1
Zhao, W1
Lu, Y1
Liu, C1
Lin, W1
Zhang, Y4
Chen, K1
Wang, H2
Zhao, L1
Sun, J3
Ding, J3
Shen, Q3
Wang, X3
Wang, M3
Huang, Y3
Zhang, X5
Zhu, H3
Zhang, F4
Wu, D3
Peng, M3
Zhang, Z5
Yuan, Y3
Li, W3
She, ZG3
Zhang, XJ3
Li, H3
Zhang, P4
Huang, Z4
Cheng, X3
Tan, X2
Wang, W5
Zhu, R2
Wu, M2
Li, M3
Chen, Y4
Liang, Z2
Zhu, P3
Wu, X2
Weng, X2
Qutob, HMH1
Saad, RA1
Bali, H1
Osailan, A1
Jaber, J1
Alzahrani, E1
Alyami, J1
Elsayed, H1
Alserihi, R1
Shaikhomar, OA1
Divya, KM1
Savitha, DP1
Krishna, GA1
Dhanya, TM1
Mohanan, PV1
Shah, SF1
Jafry, AT1
Hussain, G1
Kazim, AH1
Ali, M1
Rivani, E1
Endraswari, PD1
Widodo, ADW1
Khalil, MR1
Guldberg, R1
Nørgård, BM1
Uldbjerg, N1
Wehberg, S1
Fowobaje, KR1
Mashood, LO1
Ekholuenetale, M1
Ibidoja, OJ1
Romagnoli, A1
D'Agostino, M1
Pavoni, E1
Ardiccioni, C1
Motta, S1
Crippa, P1
Biagetti, G1
Notarstefano, V1
Rexha, J1
Perta, N1
Barocci, S1
Costabile, BK1
Colasurdo, G1
Caucci, S1
Mencarelli, D1
Turchetti, C1
Farina, M1
Pierantoni, L1
La Teana, A1
Al Hadi, R1
Cicconardi, F1
Chinappi, M1
Trucchi, E1
Mancia, F1
Menzo, S1
Morozzo Della Rocca, B1
D'Annessa, I1
Di Marino, D1
Choya, A1
de Rivas, B1
Gutiérrez-Ortiz, JI1
López-Fonseca, R1
Xu, S1
Cheng, B1
Liu, T1
Li, Y5
Jiang, L1
Guo, W1
Xiong, J1
Amirazodi, M1
Daryanoosh, F1
Mehrabi, A1
Gaeini, A1
Koushkie Jahromi, M1
Salesi, M1
Zarifkar, AH1
Studeny, P1
Netukova, M1
Nemcokova, M1
Klimesova, YM1
Krizova, D1
Kang, H1
Tao, Y1
Zhang, Q1
Sha, D1
Yao, J1
Gao, Y1
Liu, J1
Ji, L1
Shi, P1
Shi, C1
Wu, YL1
Wright, AI1
M El-Metwaly, N1
A Katouah, H1
El-Desouky, MG1
El-Bindary, AA1
El-Bindary, MA1
Kostakis, ID1
Raptis, DA1
Davidson, BR1
Iype, S1
Nasralla, D1
Imber, C1
Sharma, D1
Pissanou, T1
Pollok, JM1
Hughes, AM1
Sanderson, E1
Morris, T1
Ayorech, Z1
Tesli, M1
Ask, H1
Reichborn-Kjennerud, T1
Andreassen, OA1
Magnus, P1
Helgeland, Ø1
Johansson, S1
Njølstad, P1
Davey Smith, G1
Havdahl, A1
Howe, LD1
Davies, NM1
Amrillah, T1
Prasetio, A1
Supandi, AR1
Sidiq, DH1
Putra, FS1
Nugroho, MA1
Salsabilla, Z1
Azmi, R1
Grammatikopoulos, P1
Bouloumis, T1
Steinhauer, S1
Mironov, VS2
Bazhenova, TA2
Manakin, YV2
Yagubskii, EB2
Yakushev, IA1
Gilmutdinov, IF1
Simonov, SV1
Lan, K1
Yang, H1
Zheng, J1
Hu, H1
Zhu, T1
Zou, X1
Hu, B1
Liu, H1
Olokede, O1
Wu, H1
Holtzapple, M1
Gungor, O1
Kose, M1
Ghaemi, R1
Acker, M1
Stosic, A1
Jacobs, R1
Selvaganapathy, PR1
Ludwig, N1
Yerneni, SS1
Azambuja, JH1
Pietrowska, M1
Widłak, P1
Hinck, CS1
Głuszko, A1
Szczepański, MJ1
Kärmer, T1
Kallinger, I1
Schulz, D1
Bauer, RJ1
Spanier, G1
Spoerl, S1
Meier, JK1
Ettl, T1
Razzo, BM1
Reichert, TE1
Hinck, AP1
Whiteside, TL1
Wei, ZL1
Juan, W1
Tong, D1
Juan, LX1
Sa, LY1
Jie, HFM1
Xiao, G1
Xiang, LG1
Jie, HM1
Xu, C1
Yu, DN1
Yao, ZX1
Bigdeli, F1
Gao, XM1
Li, JZ1
Zhang, JW1
Guan, ZJ1
Bu, Y1
Liu, KG1
Morsali, A1
Das, R1
Paul, R1
Parui, A1
Shrotri, A1
Atzori, C1
Lomachenko, KA1
Singh, AK1
Mondal, J1
Peter, SC1
Florimbio, AR1
Coughlin, LN1
Bauermeister, JA1
Young, SD1
Zimmerman, MA1
Walton, MA1
Bonar, EE1
Demir, D1
Balci, AB1
Kahraman, N1
Sunbul, SA1
Gucu, A1
Seker, IB1
Badem, S1
Yuksel, A1
Ozyazicioglu, AF1
Goncu, MT1
Zhang, H2
Zhou, H1
Deng, Z1
Luo, L1
Ong, SP1
Wang, C1
Xin, H1
Whittingham, MS1
Zhou, G1
Maemura, R1
Wakamatsu, M1
Matsumoto, K1
Sakaguchi, H1
Yoshida, N1
Hama, A1
Yoshida, T1
Miwata, S1
Kitazawa, H1
Narita, K1
Kataoka, S1
Ichikawa, D1
Hamada, M1
Taniguchi, R1
Suzuki, K1
Kawashima, N1
Nishikawa, E1
Narita, A1
Okuno, Y1
Nishio, N1
Kato, K1
Kojima, S1
Morita, K1
Muramatsu, H1
Takahashi, Y1
Yirgu, A1
Mekonnen, Y1
Eyado, A1
Staropoli, A1
Vinale, F1
Zac, J1
Zac, S1
Pérez-Padilla, R1
Remigio-Luna, A1
Guzmán-Boulloud, N1
Gochicoa-Rangel, L1
Guzmán-Valderrábano, C1
Thirión-Romero, I1
Statsenko, ME1
Turkina, SV1
Barantsevich, ER1
Karakulova, YV1
Baranova, NS1
Morzhukhina, MV1
Wang, Q3
Gu, Y1
Chen, C2
Qiao, L1
Pan, F1
Song, C1
Canetto, SS1
Entilli, L1
Cerbo, I1
Cipolletta, S1
Wu, Y2
Jiang, Y1
Wang, Z1
Xie, B1
Song, T1
Luo, A1
Li, S1
Xiong, X1
Han, J1
Peng, X1
Huang, L1
Chen, Q1
Fang, W1
Hou, Y1
Zhu, Y1
Ye, J1
Liu, L1
Islam, MR1
Sanderson, P1
Johansen, MP1
Payne, TE1
Naidu, R1
Cao, J1
Yang, J1
Niu, X1
Liu, X1
Zhai, Y1
Qiang, C1
Niu, Y1
Li, Z1
Dong, N1
Wen, B1
Ouyang, Z1
Li, J2
Zhao, M1
Zhao, J2
Morici, P1
Rizzato, C1
Ghelardi, E1
Rossolini, GM1
Lupetti, A1
Gözüküçük, R1
Cakiroglu, B1
He, X2
Li, R1
Zhao, D1
Zhang, L1
Ji, X1
Fan, X1
Chen, J1
Wang, Y3
Luo, Y1
Zheng, D1
Xie, L1
Sun, S1
Cai, Z1
Liu, Q1
Ma, K1
Sun, X1
Drinkwater, JJ1
Davis, TME1
Turner, AW1
Davis, WA1
Suzuki, Y1
Mizuta, Y1
Mikagi, A1
Misawa-Suzuki, T1
Tsuchido, Y1
Sugaya, T1
Hashimoto, T1
Ema, K1
Hayashita, T1
Yang, T1
Liang, N1
Zhang, J1
Bai, Y2
Zhao, Z1
Chen, L1
Yang, M1
Huang, Q2
Hu, P1
Nagai, H1
Amanuma, M1
Mukozu, T1
Kobayashi, K1
Nagumo, H1
Mohri, K1
Watanabe, G1
Yoshimine, N1
Ogino, Y1
Daido, Y1
Matsukiyo, Y1
Matsui, T1
Wakui, N1
Momiyama, K1
Higai, K1
Matsuda, T1
Igarashi, Y1
Ishizuka, K1
Kitagawa, R1
Okubo, S1
Saito, H1
Kokubu, S1
Miyazaki, A1
Gu, S1
Fu, X1
Ye, G2
Li, X1
Zhong, S1
Tang, L1
Chen, H1
Jiang, D1
Hou, J1
Carayol, M1
Leitzmann, MF1
Ferrari, P1
Zamora-Ros, R1
Achaintre, D1
Stepien, M1
Schmidt, JA1
Travis, RC1
Overvad, K1
Tjønneland, A1
Hansen, L1
Kaaks, R1
Kühn, T1
Boeing, H1
Bachlechner, U1
Trichopoulou, A1
Bamia, C1
Palli, D1
Agnoli, C1
Tumino, R1
Vineis, P1
Panico, S1
Quirós, JR1
Sánchez-Cantalejo, E1
Huerta, JM1
Ardanaz, E1
Arriola, L1
Agudo, A1
Nilsson, J1
Melander, O1
Bueno-de-Mesquita, B1
Peeters, PH1
Wareham, N1
Khaw, KT1
Jenab, M1
Key, TJ1
Scalbert, A1
Rinaldi, S1
Fujiwara, N2
Nakagawa, H2
Enooku, K2
Kudo, Y1
Hayata, Y1
Nakatsuka, T1
Tanaka, Y1
Tateishi, R2
Hikiba, Y1
Misumi, K1
Tanaka, M1
Hayashi, A1
Shibahara, J2
Fukayama, M1
Arita, J1
Hasegawa, K1
Hirschfield, H1
Hoshida, Y2
Hirata, Y1
Otsuka, M1
Tateishi, K1
Koike, K2
Lv, J1
Chen, N1
Lou, B1
Mao, W1
Wang, P1
Lu, X3
Zhang, K1
Zhan, C1
Shi, X2
Nie, H1
Busquets, S2
Pérez-Peiró, M1
Salazar-Degracia, A1
Argilés, JM2
Serpe, R2
Rojano-Toimil, A1
López-Soriano, FJ2
Barreiro, E1
Kondo, M1
Minami, T1
Tan, Y1
Yin, P2
Gao, P2
Xu, G3
Nishikawa, H1
Osaki, Y1
Hassan, A1
Tsuda, Y1
Asai, A1
Yokohama, K1
Nakamura, K1
Sujishi, T1
Ohama, H1
Tsuchimoto, Y1
Fukunishi, S1
Abdelaal, UM1
Arafa, UA1
Hassan, AT1
Kassem, AM1
Higuchi, K1
Yaligar, J1
Teoh, WW1
Othman, R1
Verma, SK1
Phang, BH1
Lee, SS1
Wang, WW1
Toh, HC1
Gopalan, V1
Sabapathy, K1
Velan, SS1
Iwasa, M1
Sugimoto, R1
Ishihara, T1
Sekoguchi-Fujikawa, N1
Yoshikawa, K1
Mifuji-Moroka, R1
Tanaka, H1
Kobayashi, Y1
Hasegawa, H1
Takei, Y1
Elsemman, IE1
Mardinoglu, A1
Shoaie, S1
Soliman, TH1
Nielsen, J1
Al-Rejaie, SS1
Aleisa, AM1
Al-Yahya, AA1
Bakheet, SA1
Alsheikh, A1
Fatani, AG1
Al-Shabanah, OA1
Sayed-Ahmed, MM1
Zhou, L1
Xing, W1
Wu, Z1
Chen, S1
Lin, X1
Toledo, M1
Betancourt, A1
Marmonti, E1
Orpí, M1
Pin, F1
Capdevila, E1
Madeddu, C1
Mantovani, G1
Macciò, A1
Chang, B1
Nishikawa, M1
Nishiguchi, S1
Inoue, M1
Wang, T1
Wan, D1
Yang, S1
Gu, J1
Benvenga, S1
Lakshmanan, M1
Trimarchi, F1
Watkins, PA1
Ferrell, EV1
Pedersen, JI1
Hoefler, G1

Reviews

2 reviews available for carnitine and Cancer of Liver

ArticleYear
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
    Medicina clinica (English ed.), 2022, Dec-23, Volume: 159, Issue:12

    Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter

2022
Liver Cirrhosis: Evaluation, Nutritional Status, and Prognosis.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Carcinoma, Hepatocellular; Carnitine; Electric Impedance; Fibrosis; Hand Strength; Hepatitis C, Chro

2015

Trials

3 trials available for carnitine and Cancer of Liver

ArticleYear
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
    Medicina clinica (English ed.), 2022, Dec-23, Volume: 159, Issue:12

    Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter

2022
Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Cardiomyopathies; Carnitine; Dietary Supplements

2020
Effects of Oral L-Carnitine on Liver Functions after Transarterial Chemoembolization in Intermediate-Stage HCC Patients.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Administration, Oral; Aged; Amino Acids, Branched-Chain; Bilirubin; Carcinoma, Hepatocellular; Carni

2015

Other Studies

24 other studies available for carnitine and Cancer of Liver

ArticleYear
Levocarnitine Supplementation Suppresses Lenvatinib-Related Sarcopenia in Hepatocellular Carcinoma Patients: Results of a Propensity Score Analysis.
    Nutrients, 2021, Dec-10, Volume: 13, Issue:12

    Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Carnitine; Dietary Supplements; Female; Humans;

2021
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
    The EMBO journal, 2022, 08-01, Volume: 41, Issue:15

    Topics: beta Catenin; Carcinoma, Hepatocellular; Carnitine; Carrier Proteins; Cell Line, Tumor; Cell Prolife

2022
Decreased propionyl-CoA metabolism facilitates metabolic reprogramming and promotes hepatocellular carcinoma.
    Journal of hepatology, 2023, Volume: 78, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Carnitine; Citrate (si)-Synthase; Humans; Liver Neoplasms; Mice

2023
Decreased propionyl-CoA metabolism facilitates metabolic reprogramming and promotes hepatocellular carcinoma.
    Journal of hepatology, 2023, Volume: 78, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Carnitine; Citrate (si)-Synthase; Humans; Liver Neoplasms; Mice

2023
Decreased propionyl-CoA metabolism facilitates metabolic reprogramming and promotes hepatocellular carcinoma.
    Journal of hepatology, 2023, Volume: 78, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Carnitine; Citrate (si)-Synthase; Humans; Liver Neoplasms; Mice

2023
Decreased propionyl-CoA metabolism facilitates metabolic reprogramming and promotes hepatocellular carcinoma.
    Journal of hepatology, 2023, Volume: 78, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Carnitine; Citrate (si)-Synthase; Humans; Liver Neoplasms; Mice

2023
Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Antigens, CD1d; Carcinoma, Hepatocellular; Carnitine; Cellular Senescence; Galactosylceramides; Huma

2023
Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Antigens, CD1d; Carcinoma, Hepatocellular; Carnitine; Cellular Senescence; Galactosylceramides; Huma

2023
Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Antigens, CD1d; Carcinoma, Hepatocellular; Carnitine; Cellular Senescence; Galactosylceramides; Huma

2023
Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Antigens, CD1d; Carcinoma, Hepatocellular; Carnitine; Cellular Senescence; Galactosylceramides; Huma

2023
OCTN2 enhances PGC-1α-mediated fatty acid oxidation and OXPHOS to support stemness in hepatocellular carcinoma.
    Metabolism: clinical and experimental, 2023, Volume: 147

    Topics: Animals; Carcinoma, Hepatocellular; Carnitine; Cell Line, Tumor; Disease Models, Animal; Fatty Acids

2023
Effects of Lenvatinib on Skeletal Muscle Volume and Cardiac Function in Patients with Hepatocellular Carcinoma.
    Oncology, 2023, Volume: 101, Issue:10

    Topics: Adult; Carcinoma, Hepatocellular; Carnitine; Humans; Liver Neoplasms; Muscle, Skeletal; Myostatin; P

2023
High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase; CD4

2021
Blood Metabolic Signatures of Body Mass Index: A Targeted Metabolomics Study in the EPIC Cohort.
    Journal of proteome research, 2017, 09-01, Volume: 16, Issue:9

    Topics: Adult; Amino Acids; Bile Duct Neoplasms; Biogenic Amines; Blood Proteins; Body Mass Index; Carcinoma

2017
CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.
    Gut, 2018, Volume: 67, Issue:8

    Topics: Adult; Aged; Animals; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase; Case-C

2018
Dysregulated serum metabolites in staging of hepatocellular carcinoma.
    Clinical biochemistry, 2018, Volume: 61

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Carnitine; China; Cohort Studies; Docosah

2018
Metabolic profiling analysis upon acylcarnitines in tissues of hepatocellular carcinoma revealed the inhibited carnitine shuttle system caused by the downregulated carnitine palmitoyltransferase 2.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:5

    Topics: Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase

2019
Differential structural features in soleus and gastrocnemius of carnitine-treated cancer cachectic rats.
    Journal of cellular physiology, 2020, Volume: 235, Issue:1

    Topics: Animals; Autophagy; Cachexia; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase

2020
Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma.
    Scientific reports, 2019, 07-23, Volume: 9, Issue:1

    Topics: Adult; Age Factors; Aged; Carcinoma, Hepatocellular; Carnitine; Disease Progression; Female; Humans;

2019
Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics.
    Cancer research, 2013, Aug-15, Volume: 73, Issue:16

    Topics: Adult; Aged; Antioxidants; Betaine; Carcinoma, Hepatocellular; Carnitine; Citric Acid Cycle; Fatty A

2013
Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection.
    Scientific reports, 2016, Feb-02, Volume: 6

    Topics: Animals; Biomarkers; Carcinoma, Hepatocellular; Carnitine; Diffusion Magnetic Resonance Imaging; Dis

2016
Usefulness of Levocarnitine and/or Branched-Chain Amino Acids during Invasive Treatment for Hepatocellular Carcinoma.
    Journal of nutritional science and vitaminology, 2015, Volume: 61, Issue:6

    Topics: Ablation Techniques; Aged; Aged, 80 and over; Albumins; Amino Acids, Branched-Chain; Ammonia; Carcin

2015
Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism.
    Molecular bioSystems, 2016, 04-26, Volume: 12, Issue:5

    Topics: Acyl Coenzyme A; Acyltransferases; Carcinoma, Hepatocellular; Carnitine; Chromosomes, Human, Pair 1;

2016
Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats.
    World journal of gastroenterology, 2009, Mar-21, Volume: 15, Issue:11

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Carnitine; Catalase; Dietary Supplem

2009
Serum metabolomics reveals the deregulation of fatty acids metabolism in hepatocellular carcinoma and chronic liver diseases.
    Analytical and bioanalytical chemistry, 2012, Volume: 403, Issue:1

    Topics: Carcinoma, Hepatocellular; Carnitine; Chromatography, Liquid; Chronic Disease; Fatty Acids; Humans;

2012
L-Carnitine: an adequate supplement for a multi-targeted anti-wasting therapy in cancer.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:6

    Topics: Animals; Cachexia; Carcinoma, Hepatocellular; Carnitine; Caspase 3; Dietary Supplements; Liver Neopl

2012
L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria.
    International journal of cancer, 2005, Feb-20, Volume: 113, Issue:5

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Carnitine; Copper; Fatty Acids, Nonesterified; Glutat

2005
Analysis of acetylcholine, choline and butyrobetaine in human liver tissues by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2008, Aug-05, Volume: 47, Issue:4-5

    Topics: Acetylcholine; Betaine; Carcinoma, Hepatocellular; Carnitine; Choline; Chromatography, Liquid; Human

2008
Carnitine is a naturally occurring inhibitor of thyroid hormone nuclear uptake.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:12

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Carnitine; Cell Line

2000
Peroxisomal fatty acid beta-oxidation in HepG2 cells.
    Archives of biochemistry and biophysics, 1991, Volume: 289, Issue:2

    Topics: Acyl-CoA Oxidase; Antimycin A; Carcinoma, Hepatocellular; Carnitine; Cell Line; Coenzyme A Ligases;

1991