Page last updated: 2024-10-16

carnitine and Atrophy, Muscle

carnitine has been researched along with Atrophy, Muscle in 28 studies

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to elucidate the efficacy of the combination of L-carnitine and exercise, reported to prevent muscle wasting, for muscle complications (function, volume, and cramping) in patients with liver cirrhosis (LC) who received branched-chain amino acid supplementation."7.91Can L-carnitine supplementation and exercise improve muscle complications in patients with liver cirrhosis who receive branched-chain amino acid supplementation? ( Abe, M; Hiasa, Y; Hiraoka, A; Hirooka, M; Kiguchi, D; Matsuura, B; Michitaka, K; Ninomiya, T, 2019)
"Neuromuscular diseases accompanied by muscle atrophy are likely to lead to secondary carnitine deficiency, owing to the reduced amount of total carnitine stored in the body."5.91A case of Fukuyama-type congenital muscular dystrophy with acute carnitine deficiency triggered by fever, vomiting, and gastrointestinal bleeding. ( Goto, K; Hiramatsu, M; Imai, K; Korematsu, S; Uchiyama, SI; Uemura, A; Wasada, R, 2023)
"A 51-year-old man presented with acute respiratory failure and myoglobinuria precipitated by an infection."5.26Carnitine palmityl transferase deficiency: myoglobinuria and respiratory failure. ( Bertorini, T; DiMauro, S; Sabesin, S; Stadlan, E; Trevisan, C; Yeh, YY, 1980)
"The aim of this study was to elucidate the efficacy of the combination of L-carnitine and exercise, reported to prevent muscle wasting, for muscle complications (function, volume, and cramping) in patients with liver cirrhosis (LC) who received branched-chain amino acid supplementation."3.91Can L-carnitine supplementation and exercise improve muscle complications in patients with liver cirrhosis who receive branched-chain amino acid supplementation? ( Abe, M; Hiasa, Y; Hiraoka, A; Hirooka, M; Kiguchi, D; Matsuura, B; Michitaka, K; Ninomiya, T, 2019)
"It can be concluded that L-carnitine supplementation may be a good approach for a multi-targeted therapy for the treatment of cancer-related cachexia."3.78L-Carnitine: an adequate supplement for a multi-targeted anti-wasting therapy in cancer. ( Argilés, JM; Betancourt, A; Busquets, S; Capdevila, E; López-Soriano, FJ; Macciò, A; Madeddu, C; Mantovani, G; Marmonti, E; Orpí, M; Pin, F; Serpe, R; Toledo, M, 2012)
"Carnitine level and carnitine palmityl transferase (CPT) activity were investigated in muscles of patients with infantile and juvenile spinal muscular atrophy and polyneuropathies."3.67Carnitine and acyltransferase in experimental neurogenic atrophies: changes with treatment. ( Angelini, C; Armani, M; Bet, L; Bresolin, N; Freddo, L; Tegazzin, V, 1984)
"Neuromuscular diseases accompanied by muscle atrophy are likely to lead to secondary carnitine deficiency, owing to the reduced amount of total carnitine stored in the body."1.91A case of Fukuyama-type congenital muscular dystrophy with acute carnitine deficiency triggered by fever, vomiting, and gastrointestinal bleeding. ( Goto, K; Hiramatsu, M; Imai, K; Korematsu, S; Uchiyama, SI; Uemura, A; Wasada, R, 2023)
"l-Carnitine was recently found to downregulate the ubiquitin proteasome pathway (UPP) and increase insulin-like growth factor 1 concentrations in animal models."1.43l-Carnitine supplement reduces skeletal muscle atrophy induced by prolonged hindlimb suspension in rats. ( Chang, H; Jang, J; Lim, K; Park, J, 2016)
"L-Carnitine (CARN) is an essential nutrient and plays a key role in mitochondrial β-oxidation and in the ubiquitin-proteasome system regulation."1.42Potential therapeutic role of L-carnitine in skeletal muscle oxidative stress and atrophy conditions. ( Benedini, S; Luzi, L; Montesano, A; Senesi, P; Terruzzi, I, 2015)
"Carnitine depletion was associated with a 30% decrease soleus muscle weight, whereas contractile function (expressed per gram of muscle), free coenzyme A, and water content remained unaltered from CON."1.42Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency. ( Bonifacio, A; Bouitbir, J; Kaufmann, P; Krähenbühl, S; Roberts, PA; Singh, F; Urwyler, A, 2015)
"Carnitine is a key molecule in energy metabolism that helps transport activated fatty acids into the mitochondria."1.40The effect of homozygous deletion of the BBOX1 and Fibin genes on carnitine level and acyl carnitine profile. ( Akrami, SM; Rashidi-Nezhad, A; Reymond, A; Saebnouri, H; Talebi, S, 2014)
"L-carnitine was withheld for 4 months, during which time serum and muscle levels gradually decreased and no changes were observed in muscle fibers."1.28Morphometric evidence of the trophic effect of L-carnitine on human skeletal muscle. ( Corsi, M; D'Iddio, S; Giorcelli, G; Mauriello, A; Palmieri, G; Spagnoli, LG; Vacha, GM, 1990)
"A 51-year-old man presented with acute respiratory failure and myoglobinuria precipitated by an infection."1.26Carnitine palmityl transferase deficiency: myoglobinuria and respiratory failure. ( Bertorini, T; DiMauro, S; Sabesin, S; Stadlan, E; Trevisan, C; Yeh, YY, 1980)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199011 (39.29)18.7374
1990's4 (14.29)18.2507
2000's0 (0.00)29.6817
2010's9 (32.14)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Murata, K1
Kaji, K1
Nishimura, N1
Enomoto, M1
Fujimoto, Y1
Takeda, S1
Tsuji, Y1
Fujinaga, Y1
Takaya, H1
Kawaratani, H1
Namisaki, T1
Akahane, T1
Yoshiji, H1
Uchiyama, SI1
Korematsu, S1
Wasada, R1
Imai, K1
Uemura, A1
Hiramatsu, M1
Goto, K1
Noormohammadi, Z1
Arghavani, H1
Javanbakht, M1
Daneshpazhooh, M1
Jalili, M1
Zhang, N1
Valentine, JM1
Zhou, Y1
Li, ME1
Zhang, Y1
Bhattacharya, A1
Walsh, ME1
Fischer, KE1
Austad, SN1
Osmulski, P1
Gaczynska, M1
Shoelson, SE1
Van Remmen, H1
Chen, HI1
Chen, Y1
Liang, H1
Musi, N1
Endo, S1
Takahashi, T1
Sato, M1
Noya, Y1
Obana, M1
Hiraoka, A1
Kiguchi, D1
Ninomiya, T1
Hirooka, M1
Abe, M1
Matsuura, B1
Hiasa, Y1
Michitaka, K1
Busquets, S2
Pérez-Peiró, M1
Salazar-Degracia, A1
Argilés, JM2
Serpe, R2
Rojano-Toimil, A1
López-Soriano, FJ2
Barreiro, E1
Ringseis, R1
Keller, J1
Eder, K1
Rashidi-Nezhad, A1
Talebi, S1
Saebnouri, H1
Akrami, SM1
Reymond, A1
Montesano, A1
Senesi, P1
Luzi, L1
Benedini, S1
Terruzzi, I1
Roberts, PA1
Bouitbir, J1
Bonifacio, A1
Singh, F1
Kaufmann, P1
Urwyler, A1
Krähenbühl, S1
Jang, J1
Park, J1
Chang, H1
Lim, K1
Toledo, M1
Betancourt, A1
Marmonti, E1
Orpí, M1
Pin, F1
Capdevila, E1
Madeddu, C1
Mantovani, G1
Macciò, A1
Bresolin, N1
Freddo, L1
Tegazzin, V1
Bet, L1
Armani, M1
Angelini, C1
Schmidt, A1
Hässler, A1
Buxton, PH1
Bertorini, T1
Yeh, YY1
Trevisan, C1
Stadlan, E1
Sabesin, S1
DiMauro, S1
Giovenali, P1
Fenocchio, D1
Montanari, G1
Cancellotti, C1
D'Iddio, S2
Buoncristiani, U1
Pelagaggia, M1
Ribacchi, R1
Köller, H1
Stoll, G1
Neuen-Jacob, E1
Dippenaar, N1
Clauss, RP1
Feinendegen, LE1
Karpati, G1
Carpenter, S1
Engel, AG1
Watters, G1
Allen, J1
Rothman, S1
Klassen, G1
Mamer, OA1
Claireaux, AE1
Lake, BD1
Esiri, MM1
Bower, BD1
Ross, BD1
Borum, PR1
Broquist, HP1
Roelops, RJ1
Spagnoli, LG1
Palmieri, G1
Mauriello, A1
Vacha, GM1
Giorcelli, G1
Corsi, M1
Rogerson, ME1
Rylance, PB1
Wilson, R1
De Sousa, C1
Lanigan, C1
Rose, PE1
Howard, J1
Parsons, V1
Kimura, S1
Miyake, S1
Martin, JJ1
Vercruyssen, A1
de Barsy, T1
Ceuterick, C1

Reviews

2 reviews available for carnitine and Atrophy, Muscle

ArticleYear
Mechanisms underlying the anti-wasting effect of L-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies.
    European journal of nutrition, 2013, Volume: 52, Issue:5

    Topics: Animals; Carnitine; Dietary Supplements; Disease Models, Animal; Humans; Muscle, Skeletal; Muscular

2013
Pathology of muscle.
    British journal of anaesthesia, 1980, Volume: 52, Issue:2

    Topics: Adult; Carnitine; Carnitine O-Palmitoyltransferase; Child; Child, Preschool; Denervation; Female; Gl

1980

Trials

2 trials available for carnitine and Atrophy, Muscle

ArticleYear
l-carnitine downregulate the muscle wasting effect of glucocorticoids in pemphigus patient: A randomized double-blind placebo-controlled study.
    Physiological reports, 2023, Volume: 11, Issue:8

    Topics: Adult; Aged; Carnitine; Dietary Supplements; Double-Blind Method; Glucocorticoids; Humans; Insulin-L

2023
Carnitine and weakness in haemodialysis patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:5

    Topics: Administration, Oral; Biopsy; Carnitine; Electromyography; Female; Humans; Isometric Contraction; Ki

1989

Other Studies

24 other studies available for carnitine and Atrophy, Muscle

ArticleYear
Rifaximin enhances the L‑carnitine‑mediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gut‑liver‑muscle axis.
    International journal of molecular medicine, 2022, Volume: 50, Issue:2

    Topics: Animals; Carnitine; Lipopolysaccharides; Liver Cirrhosis; Muscle, Skeletal; Muscular Atrophy; Rats;

2022
A case of Fukuyama-type congenital muscular dystrophy with acute carnitine deficiency triggered by fever, vomiting, and gastrointestinal bleeding.
    Nutrition (Burbank, Los Angeles County, Calif.), 2023, Volume: 110

    Topics: Amino Acids; Carnitine; Fatty Acids; Gastrointestinal Hemorrhage; Humans; Male; Muscular Atrophy; Mu

2023
Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.
    Aging cell, 2017, Volume: 16, Issue:4

    Topics: Aging; Animals; Blood Glucose; Carnitine; Cell Line; Ceramides; Female; Gene Expression Regulation;

2017
Effects of l-Carnitine Supplementation, Botulinum Neurotoxin Injection, and Rehabilitation for a Chronic Stroke Patient.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:11

    Topics: Acetylcholine Release Inhibitors; Botulinum Toxins; Carnitine; Combined Modality Therapy; Dietary Su

2018
Can L-carnitine supplementation and exercise improve muscle complications in patients with liver cirrhosis who receive branched-chain amino acid supplementation?
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:7

    Topics: Aged; Amino Acids, Branched-Chain; Carnitine; Dietary Supplements; Electric Impedance; Exercise Ther

2019
Differential structural features in soleus and gastrocnemius of carnitine-treated cancer cachectic rats.
    Journal of cellular physiology, 2020, Volume: 235, Issue:1

    Topics: Animals; Autophagy; Cachexia; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase

2020
The effect of homozygous deletion of the BBOX1 and Fibin genes on carnitine level and acyl carnitine profile.
    BMC medical genetics, 2014, Jul-01, Volume: 15

    Topics: Abnormalities, Multiple; Calcinosis; Carnitine; Carrier Proteins; Child, Preschool; Chromosome Delet

2014
Potential therapeutic role of L-carnitine in skeletal muscle oxidative stress and atrophy conditions.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Carnitine; Cell Differentiation; Cell Line; Cell Survival; Mice; Microtubules; Muscle, Skel

2015
Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency.
    American journal of physiology. Endocrinology and metabolism, 2015, Aug-01, Volume: 309, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Carnitine; Deficiency Diseases; Disease Models, Animal; Energy Metab

2015
l-Carnitine supplement reduces skeletal muscle atrophy induced by prolonged hindlimb suspension in rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016, Volume: 41, Issue:12

    Topics: Animals; Biomarkers; Carnitine; Dietary Supplements; Enzyme Repression; Hindlimb Suspension; Immunoh

2016
L-Carnitine: an adequate supplement for a multi-targeted anti-wasting therapy in cancer.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:6

    Topics: Animals; Cachexia; Carcinoma, Hepatocellular; Carnitine; Caspase 3; Dietary Supplements; Liver Neopl

2012
Carnitine and acyltransferase in experimental neurogenic atrophies: changes with treatment.
    Journal of neurology, 1984, Volume: 231, Issue:4

    Topics: Acyltransferases; Adult; Animals; Carnitine; Denervation; Humans; Infant; Infant, Newborn; Male; Mus

1984
[Lipid storage myopathy--a contribution to the problem of the differential diagnosis of muscle dystrophy (Duchenne)].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1983, Volume: 127, Issue:3-4

    Topics: Age Factors; Carnitine; Child; Diagnosis, Differential; Humans; Lipid Metabolism; Male; Muscular Atr

1983
Carnitine palmityl transferase deficiency: myoglobinuria and respiratory failure.
    Neurology, 1980, Volume: 30, Issue:3

    Topics: Acyltransferases; Biopsy; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase

1980
Selective trophic effect of L-carnitine in type I and IIa skeletal muscle fibers.
    Kidney international, 1994, Volume: 46, Issue:6

    Topics: Carnitine; Energy Metabolism; Female; Humans; Hypertrophy; Male; Middle Aged; Muscle Contraction; Mu

1994
Postpartum manifestation of a necrotising lipid storage myopathy associated with muscle carnitine deficiency.
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 64, Issue:3

    Topics: Adult; Biopsy; Carnitine; Female; Humans; Lipid Metabolism, Inborn Errors; Muscular Atrophy; Necrosi

1998
Effect of carnitine and essential fatty acid supplementation on the uptake of 11C-carnitine in muscle of a myopathic carnitine-deficient patient using positron emission scintigraphy.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:3

    Topics: Carbon Radioisotopes; Carnitine; Child; Child, Preschool; Dietary Supplements; Fatty Acids, Essentia

1998
The syndrome of systemic carnitine deficiency. Clinical, morphologic, biochemical, and pathophysiologic features.
    Neurology, 1975, Volume: 25, Issue:1

    Topics: Adenosine Triphosphatases; Betaine; Carnitine; Child; Endoplasmic Reticulum; Forearm; Glycogen; Hist

1975
Muscle disorders in the floppy child.
    Perspectives in pediatric pathology, 1978, Volume: 4

    Topics: Biopsy; Carnitine; Child; Glycogen Storage Disease; Humans; Infant; Muscles; Muscular Atrophy; Muscu

1978
Fatal lipid storage myopathy in an infant: case report and autopsy findings.
    Journal of the neurological sciences, 1979, Volume: 41, Issue:1

    Topics: Biopsy; Carnitine; Humans; Infant; Lipid Metabolism; Lipid Metabolism, Inborn Errors; Male; Muscle H

1979
Muscle carnitine levels in neuromuscular disease.
    Journal of the neurological sciences, 1977, Volume: 34, Issue:2

    Topics: Carnitine; Humans; Methods; Muscles; Muscular Atrophy; Muscular Dystrophies; Neuromuscular Diseases

1977
Morphometric evidence of the trophic effect of L-carnitine on human skeletal muscle.
    Nephron, 1990, Volume: 55, Issue:1

    Topics: Aged; Carnitine; Female; Humans; Lipid Metabolism; Male; Middle Aged; Muscles; Muscular Atrophy; Ren

1990
Type II fiber myolysis in a patient with hypocarnitinemia.
    Brain & development, 1989, Volume: 11, Issue:4

    Topics: Biopsy; Carnitine; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Intellectual Disabili

1989
Muscle carnitine deficiency in old age. Case report and therapeutic results.
    Clinical neurology and neurosurgery, 1985, Volume: 87, Issue:4

    Topics: Aged; Biopsy; Carnitine; Electromyography; Humans; Lipid Metabolism; Lipid Metabolism, Inborn Errors

1985