carnitine has been researched along with Atherogenesis in 47 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent evidence suggests that trimethylamine-N-oxide (TMAO), a metabolite of L-carnitine and choline, is linked to atherosclerosis and cardiovascular diseases." | 8.31 | Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults. ( Abe, T; Bhuiya, J; Isomura, M; Kobayashi, H; Nabika, T; Nagai, A; Notsu, Y; Okazaki, R; Sheikh, AM; Shibly, AZ; Yamaguchi, K; Yamasaki, M; Yano, S, 2023) |
| " Among the well-known con¬tributors to atherosclerosis are less common ones, such as trimethylamine oxide (TMAO)." | 8.31 | TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS. ( Lazar, M; Olma, A; Streb, W, 2023) |
| "L-carnitine can be metabolized to trimethylamine N-oxide (TMAO), a molecule that promotes atherogenesis through its interaction with macrophages and lipid metabolism." | 7.91 | L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women. ( Grinberga, S; Hartmane, D; Lysiak-Szydlowska, W; Olek, RA; Pugovics, O; Samulak, JJ; Sawicka, AK, 2019) |
| "To evaluate plasma acylcarnitine profiles and their relationships with progression of carotid artery atherosclerosis among individuals with and without HIV infection." | 7.91 | Plasma acylcarnitines and progression of carotid artery atherosclerosis in HIV infection. ( Anastos, K; Clish, CB; Haberlen, SA; Hanna, DB; Hodis, HN; Hua, S; Kaplan, RC; Kizer, JR; Landay, AL; Lazar, JM; Post, WS; Qi, Q; Scott, JM; Shah, SJ; Yu, B, 2019) |
| "The elevation of the levels of l-carnitine and its fatty acid esters, acylcarnitines, in tissue or plasma has been linked to the development of atherosclerosis." | 7.81 | Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis. ( Cirule, H; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Vilskersts, R; Volska, K, 2015) |
| " We demonstrate here that metabolism by intestinal microbiota of dietary L-carnitine, a trimethylamine abundant in red meat, also produces TMAO and accelerates atherosclerosis in mice." | 7.79 | Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. ( Britt, EB; Brown, JM; Buffa, JA; Bushman, FD; Chen, J; DiDonato, JA; Fu, X; Hazen, SL; Koeth, RA; Krauss, RM; Levison, BS; Lewis, JD; Li, H; Li, L; Lusis, AJ; Org, E; Sheehy, BT; Smith, JD; Tang, WH; Wang, Z; Warrier, M; Wu, GD; Wu, Y, 2013) |
| "L-carnitine was first isolated from the extracts of muscle tissue in 1905 by the employees of the department of medicinal chemistry at Moscow University." | 6.50 | [Carnitine as a marker of atherosclerosis and other risks of cardiovascular diseases]. ( Dambrova, M; Kuka, Ia; Liepin'sh, É; Makretskaia, M; Vilshkersts, R, 2014) |
| "Obesity is increasing rapidly across the globe." | 5.62 | Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats. ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
| "l-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in mice via gut microbiota-dependent formation of trimethylamine (TMA) and trimethylamine N-oxide (TMAO) via a multistep pathway involving an atherogenic intermediate, γ-butyrobetaine (γBB)." | 5.30 | l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans. ( Bartlett, D; Cody, DB; Copeland, MF; Culley, MK; Dai, HJ; DiDonato, JA; Fu, X; Garcia-Garcia, JC; Gu, X; Hazen, SL; Kirsop, J; Koeth, RA; Lam-Galvez, BR; Levison, BS; Li, L; Li, XS; Tang, WHW; Wang, Z; Wu, Y, 2019) |
| "Recent evidence suggests that trimethylamine-N-oxide (TMAO), a metabolite of L-carnitine and choline, is linked to atherosclerosis and cardiovascular diseases." | 4.31 | Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults. ( Abe, T; Bhuiya, J; Isomura, M; Kobayashi, H; Nabika, T; Nagai, A; Notsu, Y; Okazaki, R; Sheikh, AM; Shibly, AZ; Yamaguchi, K; Yamasaki, M; Yano, S, 2023) |
| " Among the well-known con¬tributors to atherosclerosis are less common ones, such as trimethylamine oxide (TMAO)." | 4.31 | TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS. ( Lazar, M; Olma, A; Streb, W, 2023) |
| "L-carnitine can be metabolized to trimethylamine N-oxide (TMAO), a molecule that promotes atherogenesis through its interaction with macrophages and lipid metabolism." | 3.91 | L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women. ( Grinberga, S; Hartmane, D; Lysiak-Szydlowska, W; Olek, RA; Pugovics, O; Samulak, JJ; Sawicka, AK, 2019) |
| "To evaluate plasma acylcarnitine profiles and their relationships with progression of carotid artery atherosclerosis among individuals with and without HIV infection." | 3.91 | Plasma acylcarnitines and progression of carotid artery atherosclerosis in HIV infection. ( Anastos, K; Clish, CB; Haberlen, SA; Hanna, DB; Hodis, HN; Hua, S; Kaplan, RC; Kizer, JR; Landay, AL; Lazar, JM; Post, WS; Qi, Q; Scott, JM; Shah, SJ; Yu, B, 2019) |
| "L-carnitine supplementation elevates plasma trimethylamine-N-oxide (TMAO), which may participate in atherosclerosis development by affecting cholesterol metabolism." | 3.91 | Plasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged Women. ( Olek, RA; Samborowska, E; Samulak, JJ; Sawicka, AK, 2019) |
| " Furthermore, unlike chronic dietary choline, TML supplementation in mice failed to elevate plasma TMAO or heighten thrombosis potential in vivo." | 3.88 | Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. ( Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y, 2018) |
| "The elevation of the levels of l-carnitine and its fatty acid esters, acylcarnitines, in tissue or plasma has been linked to the development of atherosclerosis." | 3.81 | Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis. ( Cirule, H; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Vilskersts, R; Volska, K, 2015) |
| "L-carnitine, a nutrient in red meat, was recently reported to accelerate atherosclerosis via a metaorganismal pathway involving gut microbial trimethylamine (TMA) formation and host hepatic conversion into trimethylamine-N-oxide (TMAO)." | 3.80 | γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. ( Buffa, JA; Culley, MK; DiDonato, JA; Gregory, JC; Hazen, SL; Koeth, RA; Levison, BS; Li, L; Lusis, AJ; Org, E; Smith, JD; Tang, WHW; Wang, Z; Wu, Y, 2014) |
| " We demonstrate here that metabolism by intestinal microbiota of dietary L-carnitine, a trimethylamine abundant in red meat, also produces TMAO and accelerates atherosclerosis in mice." | 3.79 | Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. ( Britt, EB; Brown, JM; Buffa, JA; Bushman, FD; Chen, J; DiDonato, JA; Fu, X; Hazen, SL; Koeth, RA; Krauss, RM; Levison, BS; Lewis, JD; Li, H; Li, L; Lusis, AJ; Org, E; Sheehy, BT; Smith, JD; Tang, WH; Wang, Z; Warrier, M; Wu, GD; Wu, Y, 2013) |
| " Serum markers of endothelial dysfunction and inflammation were unchanged, but short-chain acylcarnitine concentrations were significantly decreased." | 3.79 | Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease. ( Baldwin, A; Blewett, H; Guzman, RP; O, K; Taylor, CG; Weighell, W; Wright, B; Zahradka, P, 2013) |
| "Long-term mildronate treatment decreases L-carnitine content in aortic tissues and attenuates the development of atherosclerosis in apoE/LDLR(-/-) mice." | 3.75 | Mildronate, a regulator of energy metabolism, reduces atherosclerosis in apoE/LDLR-/- mice. ( Chlopicki, S; Dambrova, M; Grinberga, S; Kalvinsh, I; Liepinsh, E; Mateuszuk, L; Vilskersts, R, 2009) |
| "Phenylacetylglutamine, for example, was recently shown to promote adverse cardiovascular phenotypes in the host via interaction with multiple ARs (adrenergic receptors)-a class of key receptors that regulate cardiovascular homeostasis." | 2.66 | Gut Microbiota and Cardiovascular Disease. ( Hazen, SL; Weeks, TL; Witkowski, M, 2020) |
| "L-carnitine was first isolated from the extracts of muscle tissue in 1905 by the employees of the department of medicinal chemistry at Moscow University." | 2.50 | [Carnitine as a marker of atherosclerosis and other risks of cardiovascular diseases]. ( Dambrova, M; Kuka, Ia; Liepin'sh, É; Makretskaia, M; Vilshkersts, R, 2014) |
| "Atherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression." | 1.72 | TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis. ( Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J, 2022) |
| "Obesity is increasing rapidly across the globe." | 1.62 | Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats. ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (8.51) | 29.6817 |
| 2010's | 35 (74.47) | 24.3611 |
| 2020's | 8 (17.02) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, X | 1 |
| Zhou, J | 1 |
| Fu, Q | 1 |
| Xu, X | 1 |
| Wei, S | 1 |
| Yang, S | 1 |
| Chen, B | 1 |
| Wang, M | 1 |
| Wang, Z | 5 |
| Lee, Y | 1 |
| Lai, HTM | 1 |
| de Oliveira Otto, MC | 1 |
| Lemaitre, RN | 1 |
| Fretts, A | 1 |
| Sotoodehnia, N | 1 |
| Budoff, M | 1 |
| DiDonato, JA | 5 |
| McKnight, B | 1 |
| Tang, WHW | 5 |
| Psaty, BM | 1 |
| Siscovick, DS | 1 |
| Hazen, SL | 8 |
| Mozaffarian, D | 1 |
| Díez-Ricote, L | 1 |
| Ruiz-Valderrey, P | 1 |
| Micó, V | 1 |
| Blanco, R | 1 |
| Tomé-Carneiro, J | 1 |
| Dávalos, A | 1 |
| Ordovás, JM | 1 |
| Daimiel, L | 1 |
| Bhuiya, J | 1 |
| Notsu, Y | 1 |
| Kobayashi, H | 1 |
| Shibly, AZ | 1 |
| Sheikh, AM | 1 |
| Okazaki, R | 1 |
| Yamaguchi, K | 1 |
| Nagai, A | 1 |
| Nabika, T | 1 |
| Abe, T | 1 |
| Yamasaki, M | 1 |
| Isomura, M | 1 |
| Yano, S | 1 |
| Olma, A | 1 |
| Streb, W | 1 |
| Lazar, M | 1 |
| Bordoni, L | 1 |
| Sawicka, AK | 3 |
| Szarmach, A | 1 |
| Winklewski, PJ | 1 |
| Olek, RA | 3 |
| Gabbianelli, R | 1 |
| Witkowski, M | 1 |
| Weeks, TL | 1 |
| Esmail, M | 1 |
| Anwar, S | 1 |
| Kandeil, M | 1 |
| El-Zanaty, AM | 1 |
| Abdel-Gabbar, M | 1 |
| Li, DY | 1 |
| Zhao, Y | 1 |
| Yang, N | 1 |
| Gao, J | 1 |
| Li, H | 2 |
| Cai, W | 1 |
| Zhang, X | 1 |
| Ma, Y | 2 |
| Niu, X | 1 |
| Yang, G | 1 |
| Zhou, X | 1 |
| Li, Y | 1 |
| Li, XS | 2 |
| Cajka, T | 1 |
| Buffa, JA | 3 |
| Nemet, I | 1 |
| Hurd, AG | 1 |
| Gu, X | 2 |
| Skye, SM | 1 |
| Roberts, AB | 1 |
| Wu, Y | 4 |
| Li, L | 4 |
| Shahen, CJ | 1 |
| Wagner, MA | 1 |
| Hartiala, JA | 1 |
| Kerby, RL | 1 |
| Romano, KA | 1 |
| Han, Y | 1 |
| Obeid, S | 1 |
| Lüscher, TF | 1 |
| Allayee, H | 1 |
| Rey, FE | 1 |
| Fiehn, O | 1 |
| Samulak, JJ | 2 |
| Hartmane, D | 1 |
| Grinberga, S | 4 |
| Pugovics, O | 2 |
| Lysiak-Szydlowska, W | 1 |
| Koeth, RA | 3 |
| Lam-Galvez, BR | 1 |
| Kirsop, J | 1 |
| Levison, BS | 3 |
| Copeland, MF | 1 |
| Bartlett, D | 1 |
| Cody, DB | 1 |
| Dai, HJ | 1 |
| Culley, MK | 2 |
| Fu, X | 2 |
| Garcia-Garcia, JC | 1 |
| Joris, BR | 1 |
| Gloor, GB | 1 |
| Wilson, C | 1 |
| Knoll, D | 1 |
| de Hora, M | 1 |
| Kyle, C | 1 |
| Glamuzina, E | 1 |
| Webster, D | 1 |
| Hua, S | 1 |
| Scott, JM | 1 |
| Hanna, DB | 1 |
| Haberlen, SA | 1 |
| Shah, SJ | 1 |
| Hodis, HN | 1 |
| Landay, AL | 1 |
| Lazar, JM | 1 |
| Kizer, JR | 1 |
| Yu, B | 1 |
| Post, WS | 1 |
| Anastos, K | 1 |
| Kaplan, RC | 1 |
| Clish, CB | 1 |
| Qi, Q | 1 |
| Sinha, A | 1 |
| Scherzer, R | 1 |
| Rahalkar, S | 1 |
| Neilan, BD | 1 |
| Crane, H | 1 |
| Drozd, D | 1 |
| Martin, J | 1 |
| Deeks, SG | 1 |
| Hunt, P | 1 |
| Hsue, PY | 1 |
| Samborowska, E | 1 |
| Chen, PY | 1 |
| Li, S | 1 |
| Koh, YC | 1 |
| Wu, JC | 1 |
| Yang, MJ | 1 |
| Ho, CT | 1 |
| Pan, MH | 1 |
| Org, E | 2 |
| Sheehy, BT | 1 |
| Britt, EB | 1 |
| Smith, JD | 2 |
| Chen, J | 1 |
| Wu, GD | 1 |
| Lewis, JD | 1 |
| Warrier, M | 1 |
| Brown, JM | 2 |
| Krauss, RM | 1 |
| Tang, WH | 2 |
| Bushman, FD | 1 |
| Lusis, AJ | 2 |
| Kugelberg, E | 1 |
| Bäckhed, F | 1 |
| Ferguson, JF | 1 |
| Dambrova, M | 4 |
| Skapare-Makarova, E | 1 |
| Konrade, I | 1 |
| Tirzite, D | 1 |
| Petrovska, R | 1 |
| Kalvins, I | 1 |
| Liepins, E | 1 |
| McCarty, MF | 1 |
| Zahradka, P | 1 |
| Wright, B | 1 |
| Weighell, W | 1 |
| Blewett, H | 1 |
| Baldwin, A | 1 |
| O, K | 1 |
| Guzman, RP | 1 |
| Taylor, CG | 1 |
| Ussher, JR | 1 |
| Lopaschuk, GD | 1 |
| Arduini, A | 1 |
| Empl, MT | 1 |
| Kammeyer, P | 1 |
| Ulrich, R | 1 |
| Joseph, JF | 1 |
| Parr, MK | 1 |
| Willenberg, I | 1 |
| Schebb, NH | 1 |
| Baumgärtner, W | 1 |
| Röhrdanz, E | 1 |
| Steffen, C | 1 |
| Steinberg, P | 1 |
| Claus, SP | 1 |
| Gregory, JC | 1 |
| Makretskaia, M | 1 |
| Vilshkersts, R | 1 |
| Kuka, Ia | 1 |
| Liepin'sh, É | 1 |
| Higuchi, T | 1 |
| Abe, M | 1 |
| Yamazaki, T | 1 |
| Mizuno, M | 1 |
| Okawa, E | 1 |
| Ando, H | 1 |
| Oikawa, O | 1 |
| Okada, K | 1 |
| Kikuchi, F | 1 |
| Soma, M | 1 |
| Drosos, I | 1 |
| Tavridou, A | 1 |
| Kolios, G | 1 |
| Vilskersts, R | 2 |
| Kuka, J | 1 |
| Liepinsh, E | 2 |
| Makrecka-Kuka, M | 1 |
| Volska, K | 1 |
| Makarova, E | 1 |
| Sevostjanovs, E | 1 |
| Cirule, H | 1 |
| Blair, HC | 1 |
| Sepulveda, J | 1 |
| Papachristou, DJ | 1 |
| Collins, HL | 1 |
| Drazul-Schrader, D | 1 |
| Sulpizio, AC | 1 |
| Koster, PD | 1 |
| Williamson, Y | 1 |
| Adelman, SJ | 1 |
| Owen, K | 1 |
| Sanli, T | 1 |
| Bellamine, A | 1 |
| Berge, RK | 2 |
| Ramsvik, MS | 1 |
| Bohov, P | 1 |
| Svardal, A | 2 |
| Nordrehaug, JE | 1 |
| Rostrup, E | 1 |
| Bruheim, I | 1 |
| Bjørndal, B | 1 |
| Trøseid, M | 1 |
| Hov, JR | 1 |
| Nestvold, TK | 1 |
| Thoresen, H | 1 |
| Lappegård, KT | 1 |
| Ryan, PM | 1 |
| London, LE | 1 |
| Bjorndahl, TC | 1 |
| Mandal, R | 1 |
| Murphy, K | 1 |
| Fitzgerald, GF | 1 |
| Shanahan, F | 1 |
| Ross, RP | 1 |
| Wishart, DS | 1 |
| Caplice, NM | 1 |
| Stanton, C | 1 |
| Mateuszuk, L | 1 |
| Kalvinsh, I | 1 |
| Chlopicki, S | 1 |
| Altmaier, E | 1 |
| Kastenmüller, G | 1 |
| Römisch-Margl, W | 1 |
| Thorand, B | 1 |
| Weinberger, KM | 1 |
| Adamski, J | 1 |
| Illig, T | 1 |
| Döring, A | 1 |
| Suhre, K | 1 |
| Xie, H | 1 |
| Yang, B | 1 |
| Zhou, XM | 1 |
| Song, FL | 1 |
| Li, JM | 1 |
| Zhou, K | 1 |
| Hu, W | 1 |
| Peng, YQ | 1 |
| Tang, SY | 1 |
| Yuan, LQ | 1 |
| Xiong, SY | 1 |
| Liao, XB | 1 |
| Mingorance, C | 1 |
| Rodriguez-Rodriguez, R | 1 |
| Justo, ML | 1 |
| Herrera, MD | 1 |
| de Sotomayor, MA | 1 |
| Pertosa, G | 1 |
| Grandaliano, G | 1 |
| Simone, S | 1 |
| Soccio, M | 1 |
| Schena, FP | 1 |
| Carrero, JJ | 1 |
| Grimble, RF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Gut Microbiota Metabolite, Trimethylamine N-oxide, in the Insulin Resistance Development[NCT05251207] | 60 participants (Anticipated) | Interventional | 2022-02-07 | Suspended (stopped due to PhD student responsible for the study has decided to terminate her education.) | |||
| CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease[NCT01731236] | Early Phase 1 | 100 participants (Anticipated) | Interventional | 2011-02-11 | Enrolling by invitation | ||
| "Plant-Based Meat vs Animal Red Meat: a Randomized Cross-over Trial"[NCT04510324] | 41 participants (Actual) | Interventional | 2020-11-01 | Completed | |||
| Impact of Facilitated Vegan Diet on Cardiometabolic Endpoints and Trimethylamine N-oxide[NCT05071196] | 70 participants (Anticipated) | Interventional | 2022-01-01 | Active, not recruiting | |||
| Impact of Diet and Gut Microbiota on Trimethylamine-N-oxide Production and Fate in Humans[NCT02558673] | 40 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)[NCT02016430] | 150 participants (Anticipated) | Interventional | 2014-04-04 | Recruiting | |||
| A Dietary Intervention With Functional Foods Reduce Metabolic Endotoxemia and Attenuates Biochemical Abnormalities in Subjects With Type 2 Diabetes by Modifying the Gut Microbiota.[NCT03421301] | 81 participants (Actual) | Interventional | 2014-08-07 | Completed | |||
| Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946] | 45 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | |||
| GutHeart: Targeting Gut Microbiota to Treat Heart Failure[NCT02637167] | Phase 2 | 150 participants (Anticipated) | Interventional | 2016-03-11 | Recruiting | ||
| A Blinded, Randomized, Controlled Study to Examine the Bioavailability of Compounds From Different Bean Varieties in Healthy Individuals.[NCT02342340] | 8 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for carnitine and Atherogenesis
| Article | Year |
|---|---|
Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease | 2020 |
Gut Microbiota and Atherosclerosis.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Diet; Disease Models, Animal; Gastrointes | 2017 |
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, | 2019 |
The decision to discontinue screening for carnitine uptake disorder in New Zealand.
Topics: Animals; Atherosclerosis; Biological Transport; Carnitine; Humans; Infant, Newborn; Methylamines; Ne | 2019 |
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Ins | 2013 |
Metaorganismal nutrient metabolism as a basis of cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Humans; Methylamines; Risk | 2014 |
The contributory role of gut microbiota in cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; I | 2014 |
[Carnitine as a marker of atherosclerosis and other risks of cardiovascular diseases].
Topics: Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carnitine; Fatty Acids, Unsaturated; Humans; V | 2014 |
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methyl | 2015 |
Nature and nurture in atherosclerosis: The roles of acylcarnitine and cell membrane-fatty acid intermediates.
Topics: Animals; Atherosclerosis; Carnitine; Cell Membrane; Dietary Fats; Disease Progression; Erythrocytes; | 2016 |
Pharmacological effects and clinical applications of propionyl-L-carnitine.
Topics: Adenosine Triphosphate; Atherosclerosis; Carbohydrate Metabolism; Cardiotonic Agents; Carnitine; End | 2011 |
Does nutrition have a role in peripheral vascular disease?
Topics: Antioxidants; Ascorbic Acid; Atherosclerosis; Carnitine; Dietary Fats, Unsaturated; Dietary Fiber; F | 2006 |
5 trials available for carnitine and Atherogenesis
| Article | Year |
|---|---|
A Pilot Study on the Effects of l-Carnitine and Trimethylamine-N-Oxide on Platelet Mitochondrial DNA Methylation and CVD Biomarkers in Aged Women.
Topics: Aged; Atherosclerosis; Biomarkers; Blood Platelets; Cardiovascular System; Carnitine; Dietary Supple | 2020 |
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Hu | 2019 |
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Hu | 2019 |
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Hu | 2019 |
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Hu | 2019 |
Meldonium decreases the diet-increased plasma levels of trimethylamine N-oxide, a metabolite associated with atherosclerosis.
Topics: Adult; Atherosclerosis; Cardiovascular Agents; Carnitine; Diet; Female; HEK293 Cells; Humans; Male; | 2013 |
Effects of levocarnitine on brachial-ankle pulse wave velocity in hemodialysis patients: a randomized controlled trial.
Topics: Administration, Oral; Aged; Ankle Brachial Index; Atherosclerosis; Biomarkers; Blood Flow Velocity; | 2014 |
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study.
Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; D | 2015 |
30 other studies available for carnitine and Atherogenesis
| Article | Year |
|---|---|
The associations between TMAO-related metabolites and blood lipids and the potential impact of rosuvastatin therapy.
Topics: Atherosclerosis; Betaine; Carnitine; Cholesterol, LDL; Choline; Humans; Lipids; Methylamines; Rosuva | 2022 |
Dietary Meat, Trimethylamine N-Oxide-Related Metabolites, and Incident Cardiovascular Disease Among Older Adults: The Cardiovascular Health Study.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Humans; Meat; Methylamines; Risk Facto | 2022 |
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation | 2022 |
Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults.
Topics: Animals; Atherosclerosis; Carnitine; Carotid Intima-Media Thickness; Choline; Cross-Sectional Studie | 2023 |
TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS.
Topics: Atherosclerosis; Carnitine; Choline; Humans; Methylamines | 2023 |
Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats.
Topics: Animals; Anti-Obesity Agents; Atherosclerosis; Atorvastatin; Blood Glucose; Body Weight; Carnitine; | 2021 |
The Effect of Different l-Carnitine Administration Routes on the Development of Atherosclerosis in ApoE Knockout Mice.
Topics: Administration, Oral; Animals; Apolipoproteins E; Atherosclerosis; Carnitine; Diet, High-Fat; Humans | 2018 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Mo | 2018 |
L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women.
Topics: Aged; Atherosclerosis; Biomarkers; Carnitine; Cholesterol; Dietary Supplements; Female; Humans; Meth | 2019 |
Plasma acylcarnitines and progression of carotid artery atherosclerosis in HIV infection.
Topics: Adult; Atherosclerosis; Carnitine; Carotid Arteries; Carotid Artery Diseases; Female; HIV Infections | 2019 |
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.
Topics: Adult; Antiretroviral Therapy, Highly Active; Atherosclerosis; Betaine; Carnitine; Carotid Artery Di | 2019 |
Plasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged Women.
Topics: Aged; Atherosclerosis; Biomarkers; Carnitine; Dietary Supplements; Female; Follow-Up Studies; Health | 2019 |
Oolong Tea Extract and Citrus Peel Polymethoxyflavones Reduce Transformation of l-Carnitine to Trimethylamine-
Topics: Animals; Atherosclerosis; Bacteria; Biotransformation; Camellia sinensis; Carnitine; Citrus; Female; | 2019 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Nutrition: Red meat consumption leads to a microbiota-dependent risk of cardiovascular disease.
Topics: Animals; Atherosclerosis; Carnitine; Female; Humans; Intestines; Metagenome | 2013 |
Meat-metabolizing bacteria in atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Female; Humans; Intestines; Metagenome | 2013 |
Meat-loving microbes: do steak-eating bacteria promote atherosclerosis?
Topics: Animals; Atherosclerosis; Carnitine; Female; Humans; Intestines; Metagenome | 2013 |
L-carnitine consumption, its metabolism by intestinal microbiota, and cardiovascular health.
Topics: Animals; Atherosclerosis; Carnitine; Female; Humans; Intestines; Metagenome | 2013 |
Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease.
Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carnitine; Carotid Steno | 2013 |
The influence of chronic L-carnitine supplementation on the formation of preneoplastic and atherosclerotic lesions in the colon and aorta of male F344 rats.
Topics: Aberrant Crypt Foci; Animals; Aorta; Atherosclerosis; Carnitine; Colon; Dietary Supplements; Dose-Re | 2015 |
Mammalian-microbial cometabolism of L-carnitine in the context of atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Female; Gastrointestinal Tract; Methylamines | 2014 |
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Female; Gastrointestinal Tract; Methylamines; Mice; Mi | 2014 |
Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Betaine; Carnitine; Disease Progression; Female; | 2015 |
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE(-/-) transgenic mice expressing CETP.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Carnitine; Cells, Cultured; Cholesterol Ester Transfer | 2016 |
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnit | 2016 |
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E
Topics: Acetates; Animals; Apolipoproteins E; Atherosclerosis; Atorvastatin; beta-Glucans; Butyrates; Cardio | 2017 |
Mildronate, a regulator of energy metabolism, reduces atherosclerosis in apoE/LDLR-/- mice.
Topics: Animals; Aorta; Atherosclerosis; Betaine; Cardiovascular Agents; Carnitine; Energy Metabolism; Femal | 2009 |
Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics.
Topics: Aged; Atherosclerosis; Carnitine; Cholesterol; Coffee; Humans; Male; Metabolomics; Middle Aged; Sphi | 2009 |
L-carnitine and taurine synergistically inhibit the proliferation and osteoblastic differentiation of vascular smooth muscle cells.
Topics: Animals; Atherosclerosis; Calcium; Carnitine; Cell Differentiation; Cell Proliferation; Cells, Cultu | 2010 |
Inflammation and carnitine in hemodialysis patients.
Topics: Atherosclerosis; Carnitine; Chemokine CCL2; Humans; Inflammation; Interleukin-6; JNK Mitogen-Activat | 2005 |