carnitine has been researched along with Ataxia Telangiectasia in 1 studies
Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, the modulating effect of L-carnitine on tert-butyl-hydroperoxide-induced DNA damage was compared with that of mannitol, a well known scavenger of hydroxyl radicals, both in normal and Ataxia telangiectasia mutated (ATM)-deficient lymphoblastoid cell lines established from A." | 7.74 | L-carnitine enhances resistance to oxidative stress by reducing DNA damage in Ataxia telangiectasia cells. ( Berni, A; Chessa, L; De Amicis, A; Filippi, S; Meschini, R; Palitti, F, 2008) |
| "In this study, the modulating effect of L-carnitine on tert-butyl-hydroperoxide-induced DNA damage was compared with that of mannitol, a well known scavenger of hydroxyl radicals, both in normal and Ataxia telangiectasia mutated (ATM)-deficient lymphoblastoid cell lines established from A." | 3.74 | L-carnitine enhances resistance to oxidative stress by reducing DNA damage in Ataxia telangiectasia cells. ( Berni, A; Chessa, L; De Amicis, A; Filippi, S; Meschini, R; Palitti, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berni, A | 1 |
| Meschini, R | 1 |
| Filippi, S | 1 |
| Palitti, F | 1 |
| De Amicis, A | 1 |
| Chessa, L | 1 |
1 other study available for carnitine and Ataxia Telangiectasia
| Article | Year |
|---|---|
L-carnitine enhances resistance to oxidative stress by reducing DNA damage in Ataxia telangiectasia cells.
Topics: Ataxia Telangiectasia; Carnitine; Cell Cycle; Cell Line; Chromosome Aberrations; Comet Assay; DNA Da | 2008 |