Page last updated: 2024-10-16

carnitine and Asthma

carnitine has been researched along with Asthma in 7 studies

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Serum carnitine levels decrease in children with moderate asthma during exacerbation of asthma and shortly thereafter."7.75Serum total and free carnitine levels in children with asthma. ( Asilsoy, S; Bekem, O; Karaman, O; Kavukçu, S; Uzuner, N, 2009)
"Asthma is a heterogeneous disease with poorly defined phenotypes."5.72Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. ( Adcock, IM; Bakke, PS; Baribaud, F; Bates, S; Behndig, A; Broadhurst, DI; Caruso, M; Chaleckis, R; Chanez, P; Chung, KF; Dahlén, B; Dahlén, SE; Djukanovic, R; Ericsson, M; Fowler, SJ; Gallart-Ayala, H; Geiser, T; Gómez, C; Horváth, I; Howarth, P; Hu, S; Kermani, NZ; Kolmert, J; Krug, N; Lasky-Su, J; Loza, M; Lundqvist, A; Montuschi, P; Musial, J; Naz, S; Olsson, H; Reinke, SN; Riley, JH; Scholfield, J; Shaw, DE; Singer, F; Sousa, AR; Sterk, PJ; Ström, M; Tiotiu, A; Wheelock, ÅM; Wheelock, CE, 2022)
"L-carnitine has been reported to influence respiratory functions."5.31The role of L-carnitine in treatment of a murine model of asthma. ( Işlekel, H; Karaman, O; Kargi, A; Kavukçu, S; Ozkal, S; Soylu, A; Uzuner, N; Yilmaz, O, 2002)
"To evaluate whether PDSC, an L-carnitine ester derivative of prednisolone and OCTN2 substrate, could provide a targeted delivery of the corticosteroid into the lung tissues of an asthmatic guinea pig model."3.80L-Carnitine ester of prednisolone: pharmacokinetic and pharmacodynamic evaluation of a type I prodrug. ( Lim, LY; Mo, J; Zhang, ZR, 2014)
"Serum carnitine levels decrease in children with moderate asthma during exacerbation of asthma and shortly thereafter."3.75Serum total and free carnitine levels in children with asthma. ( Asilsoy, S; Bekem, O; Karaman, O; Kavukçu, S; Uzuner, N, 2009)
"Asthma is a heterogeneous disease with poorly defined phenotypes."1.72Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. ( Adcock, IM; Bakke, PS; Baribaud, F; Bates, S; Behndig, A; Broadhurst, DI; Caruso, M; Chaleckis, R; Chanez, P; Chung, KF; Dahlén, B; Dahlén, SE; Djukanovic, R; Ericsson, M; Fowler, SJ; Gallart-Ayala, H; Geiser, T; Gómez, C; Horváth, I; Howarth, P; Hu, S; Kermani, NZ; Kolmert, J; Krug, N; Lasky-Su, J; Loza, M; Lundqvist, A; Montuschi, P; Musial, J; Naz, S; Olsson, H; Reinke, SN; Riley, JH; Scholfield, J; Shaw, DE; Singer, F; Sousa, AR; Sterk, PJ; Ström, M; Tiotiu, A; Wheelock, ÅM; Wheelock, CE, 2022)
"L-carnitine has been reported to influence respiratory functions."1.31The role of L-carnitine in treatment of a murine model of asthma. ( Işlekel, H; Karaman, O; Kargi, A; Kavukçu, S; Ozkal, S; Soylu, A; Uzuner, N; Yilmaz, O, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Reinke, SN1
Naz, S1
Chaleckis, R1
Gallart-Ayala, H1
Kolmert, J1
Kermani, NZ1
Tiotiu, A1
Broadhurst, DI1
Lundqvist, A1
Olsson, H1
Ström, M1
Wheelock, ÅM1
Gómez, C1
Ericsson, M1
Sousa, AR1
Riley, JH1
Bates, S1
Scholfield, J1
Loza, M1
Baribaud, F1
Bakke, PS1
Caruso, M1
Chanez, P1
Fowler, SJ1
Geiser, T1
Howarth, P1
Horváth, I1
Krug, N1
Montuschi, P1
Behndig, A1
Singer, F1
Musial, J1
Shaw, DE1
Dahlén, B1
Hu, S1
Lasky-Su, J1
Sterk, PJ1
Chung, KF1
Djukanovic, R1
Dahlén, SE1
Adcock, IM1
Wheelock, CE1
Loureiro, CC2
Duarte, IF1
Gomes, J1
Carrola, J1
Barros, AS1
Gil, AM1
Bousquet, J2
Bom, AT1
Rocha, SM2
Amaral, AF1
Todo Bom, A1
Mo, J1
Lim, LY1
Zhang, ZR1
Asilsoy, S1
Bekem, O1
Karaman, O2
Uzuner, N2
Kavukçu, S2
Yilmaz, O1
Ozkal, S1
Işlekel, H1
Soylu, A1
Kargi, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Protocol for the European Multi-Centre Study Understanding Severe Asthma Longitudinal Assessment of Adults With Severe Asthma[NCT01976767]725 participants (Actual)Observational2011-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for carnitine and Asthma

ArticleYear
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
    The European respiratory journal, 2022, Volume: 59, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Carnitine; Cross-Sectional Studies; Humans;

2022
Urinary metabolomic changes as a predictive biomarker of asthma exacerbation.
    The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:1

    Topics: Adult; Aged; Asthma; Biomarkers; Carnitine; Cohort Studies; Disease Progression; Female; Gas Chromat

2014
Metabolomics of asthma.
    The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:5

    Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Ser

2014
Reply: To PMID 24369803.
    The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:5

    Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Ser

2014
L-Carnitine ester of prednisolone: pharmacokinetic and pharmacodynamic evaluation of a type I prodrug.
    International journal of pharmaceutics, 2014, Nov-20, Volume: 475, Issue:1-2

    Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Carn

2014
Serum total and free carnitine levels in children with asthma.
    World journal of pediatrics : WJP, 2009, Volume: 5, Issue:1

    Topics: Adolescent; Asthma; Carnitine; Case-Control Studies; Child; Child, Preschool; Female; Humans; Male;

2009
The role of L-carnitine in treatment of a murine model of asthma.
    Acta medica Okayama, 2002, Volume: 56, Issue:6

    Topics: Animals; Asthma; Carnitine; Disease Models, Animal; Leukotriene E4; Lung; Methacholine Chloride; Mic

2002