carnitine has been researched along with Ascorbic Acid Deficiency in 17 studies
Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ascorbic acid deficiency in guinea pigs resulted in decreased activity of hepatic gamma-butyrobetaine hydroxylase and renal but not hepatic epsilon-N-trimethyllsine hydroxylase when exogenous substrates were provided." | 4.78 | Ascorbic acid and carnitine biosynthesis. ( Rebouche, CJ, 1991) |
| "These data indicate that blood histamine and plasma free carnitine are altered in individuals with subnormal, non-scorbutic vitamin C status and provide evidence that metabolic changes independent of collagen metabolism occur prior to the manifestation of scurvy." | 3.69 | Vitamin C depletion is associated with alterations in blood histamine and plasma free carnitine in adults. ( Corte, C; Johnston, CS; Solomon, RE, 1996) |
| "Severe and long-term vitamin C deficiency can lead to fatal scurvy, which is fortunately considered rare today." | 2.72 | Vitamin C Deficiency in the Young Brain-Findings from Experimental Animal Models. ( Tveden-Nyborg, P, 2021) |
| "Carnitine is an essential cofactor in the transport of long-chain fatty acids into the mitochondrial matrix and plays an important role in energy production via beta-oxidation." | 1.35 | Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice. ( Amano, A; Furusawa, H; Goto, S; Handa, S; Inai, Y; Ishigami, A; Iwama, M; Kondo, Y; Maruyama, N; Murata, A; Nishikimi, M; Sato, Y; Takahashi, R; Tanaka, Y, 2008) |
| "Experimental vitamin C deficiency in guinea pigs is associated with low carnitine concentrations in blood and some tissues." | 1.29 | The ability of guinea pigs to synthesize carnitine at a normal rate from epsilon-N-trimethyllysine or gamma-butyrobetaine in vivo is not compromised by experimental vitamin C deficiency. ( Rebouche, CJ, 1995) |
| "Experimental vitamin C deficiency is associated with carnitine concentrations in blood and some tissues, but is not due to a decreased ability of scorbutic animals to synthesize carnitine." | 1.29 | Renal handling of carnitine in experimental vitamin C deficiency. ( Rebouche, CJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Tveden-Nyborg, P | 1 |
| Casaer, MP | 1 |
| Bellomo, R | 1 |
| Furusawa, H | 1 |
| Sato, Y | 1 |
| Tanaka, Y | 1 |
| Inai, Y | 1 |
| Amano, A | 1 |
| Iwama, M | 1 |
| Kondo, Y | 1 |
| Handa, S | 1 |
| Murata, A | 1 |
| Nishikimi, M | 1 |
| Goto, S | 1 |
| Maruyama, N | 1 |
| Takahashi, R | 1 |
| Ishigami, A | 1 |
| Okamoto, M | 1 |
| Ueno, Y | 1 |
| Kolb, E | 1 |
| Dunn, WA | 1 |
| Rettura, G | 1 |
| Seifter, E | 1 |
| Englard, S | 2 |
| Thoma, WJ | 1 |
| Henderson, LM | 2 |
| Nelson, PJ | 1 |
| Pruitt, RE | 1 |
| Henderson, LL | 1 |
| Jenness, R | 1 |
| Sandor, A | 2 |
| Kispal, G | 1 |
| Kerner, J | 1 |
| Alkonyi, I | 2 |
| Hughes, RE | 1 |
| Hurley, RJ | 1 |
| Jones, E | 1 |
| Rebouche, CJ | 3 |
| Johnston, CS | 1 |
| Solomon, RE | 1 |
| Corte, C | 1 |
| Ha, TY | 1 |
| Otsuka, M | 1 |
| Arakawa, N | 1 |
| Cseko, J | 1 |
| Seifter, S | 1 |
4 reviews available for carnitine and Ascorbic Acid Deficiency
| Article | Year |
|---|---|
Vitamin C Deficiency in the Young Brain-Findings from Experimental Animal Models.
Topics: Animals; Antioxidants; Ascorbic Acid; Ascorbic Acid Deficiency; Brain; Carnitine; Fatty Acids, Unsat | 2021 |
[Recent knowledge concerning the biochemistry and significance of ascorbic acid].
Topics: Age Factors; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carnitine; Collagen; Glycosaminoglyca | 1984 |
Ascorbic acid and carnitine biosynthesis.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carnitine; gamma-Butyrobetaine Dioxygenase; Humans | 1991 |
The biochemical functions of ascorbic acid.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carnitine; Ce | 1986 |
13 other studies available for carnitine and Ascorbic Acid Deficiency
| Article | Year |
|---|---|
Micronutrient deficiency in critical illness: an invisible foe?
Topics: Ascorbic Acid Deficiency; Carnitine; Critical Illness; Folic Acid; Humans; Micronutrients; Nutrition | 2019 |
Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Calcium-Binding Proteins; Carboxylic | 2008 |
Is sudden death with vitamin C deficiency caused by lack of carnitine?
Topics: Animals; Ascorbic Acid Deficiency; Autopsy; Carnitine; Death, Sudden, Cardiac; Female; Myocytes, Car | 2006 |
Carnitine biosynthesis from gamma-butyrobetaine and from exogenous protein-bound 6-N-trimethyl-L-lysine by the perfused guinea pig liver. Effect of ascorbate deficiency on the in situ activity of gamma-butyrobetaine hydroxylase.
Topics: Animals; Ascorbic Acid Deficiency; Betaine; Carbon Radioisotopes; Carnitine; gamma-Butyrobetaine Dio | 1984 |
Effect of vitamin C deficiency on hydroxylation of trimethylaminobutyrate to carnitine in the guinea pig.
Topics: Animals; Ascorbic Acid Deficiency; Carnitine; gamma-Aminobutyric Acid; gamma-Butyrobetaine Dioxygena | 1984 |
Effect of ascorbic acid deficiency on the in vivo synthesis of carnitine.
Topics: Animals; Ascorbic Acid Deficiency; Body Weight; Carnitine; gamma-Aminobutyric Acid; Guinea Pigs; Kid | 1981 |
Combined effect of ascorbic acid deficiency and underfeeding on the hepatic carnitine level in guinea-pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carnitine; Food Deprivation; Guinea Pigs; Liver; M | 1983 |
Dietary ascorbic acid and muscle carnitine (beta-OH-gamma-(trimethylamino) butyric acid) in guinea-pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carnitine; Diet; Guinea Pigs; Male; Muscles | 1980 |
The ability of guinea pigs to synthesize carnitine at a normal rate from epsilon-N-trimethyllysine or gamma-butyrobetaine in vivo is not compromised by experimental vitamin C deficiency.
Topics: Analysis of Variance; Animals; Ascorbic Acid Deficiency; Betaine; Carnitine; Food, Fortified; Guinea | 1995 |
Renal handling of carnitine in experimental vitamin C deficiency.
Topics: Amino Acids; Animals; Ascorbic Acid Deficiency; Biological Transport; Biomarkers; Carnitine; Guinea | 1995 |
Vitamin C depletion is associated with alterations in blood histamine and plasma free carnitine in adults.
Topics: Adult; Ascorbic Acid; Ascorbic Acid Deficiency; Carnitine; Female; Histamine; Humans; Male; Scurvy | 1996 |
The effect of graded doses of ascorbic acid on the tissue carnitine and plasma lipid concentrations.
Topics: Alkaline Phosphatase; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Carnitine; Chol | 1990 |
Role of the liver in carnitine metabolism: the mechanism of development of carnitine-deficient status in guinea-pigs.
Topics: Animals; Ascorbic Acid Deficiency; Betaine; Carnitine; Guinea Pigs; Liver; Male; Starvation | 1990 |