Page last updated: 2024-10-16

carnitine and Arteriosclerosis

carnitine has been researched along with Arteriosclerosis in 15 studies

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
"Chronic hemodialysis (HD) patients frequently encounter carnitine depletion, elevated adipose tissue-derived hormones/cytokines, that may contribute to accelerated arteriosclerosis."5.14L-carnitine supplementation and adipokines in patients with end-stage renal disease on regular hemodialysis. ( Csiky, B; Melegh, B; Nyul, Z; Rascher, W; Rauh, M; Sulyok, E; Tóth, G; Wittmann, I, 2010)
" The authors, on the basis of recent studies demonstrating the rheological and vasoactive as well as metabolic activities of levocarnitine propionyl, have decided to use this substance in the treatment of arteriopathics affected by intermittent claudication."5.07Evaluation of the therapeutic efficacy and tolerability of levocarnitine propionyl in the treatment of chronic obstructive arteriopathies of the lower extremities: a multicentre controlled study vs. placebo. ( Coto, V; D'Alessandro, L; Grattarola, G; Imparato, L; Lingetti, M; Mancini, M; Nolfe, G; Rengo, F, 1992)
"Carnitine has a dual role as it is required for long-chain fatty acid oxidation, and also shuttles accumulated acyl groups out of the mitochondria."2.40The role of carnitine and carnitine supplementation during exercise in man and in individuals with special needs. ( Brass, EP; Hiatt, WR, 1998)
") at a dosage of 1."1.28Cerebral blood flow in patients with chronic cerebrovascular disease: effect of acetyl L-carnitine. ( Cicerano, U; De Chiara, S; Gallotta, G; Mancini, M; Postiglione, A; Salvatore, M; Soricelli, A, 1990)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's5 (33.33)18.2507
2000's4 (26.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Csiky, B1
Nyul, Z1
Tóth, G1
Wittmann, I1
Melegh, B1
Rauh, M1
Rascher, W1
Sulyok, E1
Hiatt, WR2
Lofgren, I1
Zern, T1
Herron, K1
West, K1
Sharman, MJ1
Volek, JS1
Shachter, NS1
Koo, SI1
Fernandez, ML1
Lacour, B1
Di Giulio, S1
Chanard, J1
Ciancioni, C1
Haguet, M1
Lebkiri, B1
Basile, C1
Drüeke, T1
Assan, R1
Funck-Brentano, JL1
Maebashi, M1
Imamura, A1
Yoshinaga, K1
Spagnoli, LG1
Orlandi, A1
Marino, B1
Mauriello, A1
De Angelis, C1
Ramacci, MT1
Brass, EP1
Sayed-Ahmed, MM1
Khattab, MM1
Gad, MZ1
Mostafa, N1
Signorelli, SS1
Malaponte, G1
Di Pino, L1
Digrandi, D1
Pennisi, G1
Mazzarino, MC1
Coto, V1
D'Alessandro, L1
Grattarola, G1
Imparato, L1
Lingetti, M1
Mancini, M2
Nolfe, G1
Rengo, F1
Mimura, K1
Yukawa, S1
Postiglione, A1
Cicerano, U1
Soricelli, A1
De Chiara, S1
Gallotta, G1
Salvatore, M1
Kirk, JE2
Hashimoto, S1
Dayton, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940]Phase 3120 participants (Actual)Interventional2018-05-28Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for carnitine and Arteriosclerosis

ArticleYear
Treatment of disability in peripheral arterial disease: new drugs.
    Current drug targets. Cardiovascular & haematological disorders, 2004, Volume: 4, Issue:3

    Topics: Arteriosclerosis; Carnitine; Clinical Trials as Topic; Exercise Therapy; Humans; Hypolipidemic Agent

2004
The role of carnitine and carnitine supplementation during exercise in man and in individuals with special needs.
    Journal of the American College of Nutrition, 1998, Volume: 17, Issue:3

    Topics: Arteriosclerosis; Carnitine; Clinical Trials as Topic; Dietary Supplements; Energy Metabolism; Exerc

1998

Trials

4 trials available for carnitine and Arteriosclerosis

ArticleYear
L-carnitine supplementation and adipokines in patients with end-stage renal disease on regular hemodialysis.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:10

    Topics: Adipokines; Aged; Aged, 80 and over; Arteriosclerosis; Carnitine; Female; Humans; Infusions, Intrave

2010
Weight loss associated with reduced intake of carbohydrate reduces the atherogenicity of LDL in premenopausal women.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:9

    Topics: Adult; Arteriosclerosis; Caloric Restriction; Carnitine; Cholesterol, LDL; Dietary Carbohydrates; Di

2005
Effects of ischaemic stress on leukocyte activation processes in patients with chronic peripheral occlusive arterial disease: role of L-propionyl carnitine administration.
    Pharmacological research, 2001, Volume: 44, Issue:4

    Topics: Aged; Arteriosclerosis; Cardiotonic Agents; Carnitine; Cell Adhesion Molecules; Chronic Disease; E-S

2001
Evaluation of the therapeutic efficacy and tolerability of levocarnitine propionyl in the treatment of chronic obstructive arteriopathies of the lower extremities: a multicentre controlled study vs. placebo.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:1

    Topics: Administration, Oral; Aged; Analysis of Variance; Arterial Occlusive Diseases; Arteriosclerosis; Car

1992

Other Studies

9 other studies available for carnitine and Arteriosclerosis

ArticleYear
Carnitine improves lipid anomalies in haemodialysis patients.
    Lancet (London, England), 1980, Oct-11, Volume: 2, Issue:8198

    Topics: Adult; Arteriosclerosis; Carnitine; Cholesterol; Female; Humans; Kidney Failure, Chronic; Lipids; Li

1980
Effect of aging on lipid and carnitine metabolism.
    The Tohoku journal of experimental medicine, 1982, Volume: 138, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Arteriosclerosis; Carnitine; Drug Synergism; Fatty

1982
Propionyl-L-carnitine prevents the progression of atherosclerotic lesions in aged hyperlipemic rabbits.
    Atherosclerosis, 1995, Apr-07, Volume: 114, Issue:1

    Topics: Aging; Animals; Arteriosclerosis; Carnitine; Cell Division; Diet; Disease Models, Animal; Female; Fo

1995
L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolaemic rabbits.
    Pharmacological research, 2001, Volume: 44, Issue:3

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Carnitine; Coronary Vessels; Hypercholesterolemia; Male;

2001
[Hyperlipidemia and drug treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidn

1991
Cerebral blood flow in patients with chronic cerebrovascular disease: effect of acetyl L-carnitine.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:1-2

    Topics: Acetylcarnitine; Aged; Arteriosclerosis; Carnitine; Cerebrovascular Circulation; Cerebrovascular Dis

1990
Coenzyme contents of arterial tissue.
    Monographs on atherosclerosis, 1974, Volume: 4, Issue:0

    Topics: Age Factors; Animals; Aorta; Arteries; Arteriosclerosis; Carnitine; Chromatography, Paper; Coenzyme

1974
Oxidation of palmityl-CoA to CO2 by normal and atherosclerotic aortic mitochondria.
    Life sciences, 1974, Mar-01, Volume: 14, Issue:5

    Topics: Adenosine Diphosphate; Albumins; Animals; Aorta; Arteriosclerosis; Carbon Dioxide; Carbon Radioisoto

1974
Carnitine (free carnitine).
    Monographs on atherosclerosis, 1974, Volume: 4, Issue:0

    Topics: Age Factors; Aging; Aorta; Arteries; Arteriosclerosis; Carnitine; Humans; Iliac Artery; Iliac Vein;

1974