Page last updated: 2024-10-16

carnitine and Angor Pectoris

carnitine has been researched along with Angor Pectoris in 26 studies

Research Excerpts

ExcerptRelevanceReference
"Among patients with suspected stable angina pectoris, elevated serum even-chained acylcarnitines were associated with increased risk of cardiovascular death and, to a lesser degree with acute myocardial infarction, independent of traditional risk factors."7.85Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris. ( Berge, RK; Bjørndal, B; Dierkes, J; Karlsson, T; Mellgren, G; Njølstad, PR; Nygård, O; Olsen, T; Pedersen, ER; Strand, E; Svardal, A; Svingen, GF; Tell, GS, 2017)
"To evaluate the therapeutic efficacy of l-carnitine in heart failure, the myocardial carnitine levels and the therapeutic efficacy of l-carnitine were studied in cardiomyopathic BIO 14."7.68L-carnitine treatment for congestive heart failure--experimental and clinical study. ( Kobayashi, A; Masumura, Y; Yamazaki, N, 1992)
"L-carnitine was administered orally in doses of 3 g/day for 30 days to 16 subjects with effort-induced angina and to 14 healthy subjects."5.27Bicycle ergometer and echocardiographic study in healthy subjects and patients with angina pectoris after administration of L-carnitine: semiautomatic computerized analysis of M-mode tracing. ( Biagini, A; Canale, C; Castellano, A; Masperone, MA; Terrachini, V; Valice, S; Vallebona, A, 1988)
"Infusions of DL-carnitine are reported to improve the tolerance to atrial pacing of patients with angina pectoris."5.05Intravenous dl-carnitine fails to increase the double-product during atrial pacing in patients with effort angina. A double-blind randomized study. ( Biagini, A; Carpeggiani, C; Maseri, A; Mazzei, MG; Opie, L; Rovai, D, 1983)
"A systematic review and meta-analysis of 13 controlled trials (N=3629) was conducted to determine the effects of L-carnitine vs placebo or control on mortality, ventricular arrhythmias (VAs), angina, heart failure, and reinfarction."4.89L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. ( DiNicolantonio, JJ; Fares, H; Lavie, CJ; Menezes, AR; O'Keefe, JH, 2013)
"Among patients with suspected stable angina pectoris, elevated serum even-chained acylcarnitines were associated with increased risk of cardiovascular death and, to a lesser degree with acute myocardial infarction, independent of traditional risk factors."3.85Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris. ( Berge, RK; Bjørndal, B; Dierkes, J; Karlsson, T; Mellgren, G; Njølstad, PR; Nygård, O; Olsen, T; Pedersen, ER; Strand, E; Svardal, A; Svingen, GF; Tell, GS, 2017)
"To evaluate the therapeutic efficacy of l-carnitine in heart failure, the myocardial carnitine levels and the therapeutic efficacy of l-carnitine were studied in cardiomyopathic BIO 14."3.68L-carnitine treatment for congestive heart failure--experimental and clinical study. ( Kobayashi, A; Masumura, Y; Yamazaki, N, 1992)
"L-carnitine was randomly administered to 81 patients at an oral dose of g 4/die for 12 months, in addition to the pharmacological treatment generally used."2.67Controlled study on L-carnitine therapeutic efficacy in post-infarction. ( Bigalli, A; Boem, A; Davini, P; Lamanna, F, 1992)
"L-carnitine was studied in forty-four men with stable chronic angina in a multicenter, double-blind, randomized, placebo controlled crossover trial."2.66Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo controlled crossover study. ( Angelino, F; Caponnetto, S; Cherchi, A; Lai, C; Manzoli, U; Mereto, PE; Reale, A; Rosolen, G; Schiavoni, G; Trucco, G, 1985)
" Unfortunately, there is no reason to believe that these drugs inhibit fat oxidation selectively in the heart; thus, chronic use of these drugs can be expected to increase body fat stores until the original rate of fat oxidation is restored by mass action - presumably negating the therapeutic benefit in angina, while exacerbating the manifold adverse effects of insulin resistance syndrome."1.32A shift in myocardial substrate, improved endothelial function, and diminished sympathetic activity may contribute to the anti-anginal impact of very-low-fat diets. ( McCarty, MF, 2004)
"L-carnitine was administered orally in doses of 3 g/day for 30 days to 16 subjects with effort-induced angina and to 14 healthy subjects."1.27Bicycle ergometer and echocardiographic study in healthy subjects and patients with angina pectoris after administration of L-carnitine: semiautomatic computerized analysis of M-mode tracing. ( Biagini, A; Canale, C; Castellano, A; Masperone, MA; Terrachini, V; Valice, S; Vallebona, A, 1988)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19908 (30.77)18.7374
1990's12 (46.15)18.2507
2000's4 (15.38)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DiNicolantonio, JJ1
Lavie, CJ1
Fares, H1
Menezes, AR1
O'Keefe, JH1
Strand, E1
Pedersen, ER1
Svingen, GF1
Olsen, T1
Bjørndal, B1
Karlsson, T1
Dierkes, J1
Njølstad, PR1
Mellgren, G1
Tell, GS1
Berge, RK1
Svardal, A1
Nygård, O1
César, LA1
Gowdak, LH1
Mansur, AP1
McCarty, MF1
Sweeney, M1
Kamikawa, T1
Suzuki, Y1
Kobayashi, A2
Hayashi, H1
Masumura, Y2
Nishihara, K1
Abe, M1
Yamazaki, N2
Biagini, A2
Opie, L1
Rovai, D1
Mazzei, MG1
Carpeggiani, C1
Maseri, A1
Ferrari, R1
Cucchini, F1
Visioli, O1
Ribeiro, C1
Chierchia, SL1
Fragasso, G1
Bartels, GL4
Remme, WJ4
Pillay, M2
Schönfeld, DH2
Kruijssen, DA3
Holwerda, KJ1
den Hartog, FR1
Wielenga, RP1
Iyer, RN1
Khan, AA1
Gupta, A1
Vajifdar, BU1
Lokhandwala, YY1
Opie, LH1
Cherchi, A3
Fonzo, R1
Lai, C3
Mercuro, G1
Corsi, M2
Davini, P1
Bigalli, A1
Lamanna, F1
Boem, A1
Cox, PH1
Kruijssen, HA1
Knufman, NM1
Fernandez, C1
Proto, C1
Lagioia, R1
Scrutinio, D1
Mangini, SG1
Ricci, A1
Mastropasqua, F1
Valentini, G1
Ramunni, G1
Totaro Fila, G1
Rizzon, P1
Cacciatore, L1
Cerio, R1
Ciarimboli, M1
Cocozza, M1
Coto, V1
D'Alessandro, A1
D'Alessandro, L1
Grattarola, G1
Imparato, L1
Lingetti, M1
Onnis, E1
Orani, E1
Pirisi, R1
Pisano, MR1
Soro, A1
Canale, C1
Terrachini, V1
Vallebona, A1
Masperone, MA1
Valice, S1
Castellano, A1
Angelino, F1
Trucco, G1
Caponnetto, S1
Mereto, PE1
Rosolen, G1
Manzoli, U1
Schiavoni, G1
Reale, A1
Strano, A1
Novo, S1
Adamo, L1
Raineri, M1
Bruno Gallo, V1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Double Blind Study of the Effects of Homocysteine Lowering Therapy on Mortality and Cardiac Events in Patients Undergoing Coronary Angiography[NCT00354081]Phase 33,096 participants (Actual)Interventional1999-04-30Completed
Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940]Phase 3120 participants (Actual)Interventional2018-05-28Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for carnitine and Angor Pectoris

ArticleYear
L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis.
    Mayo Clinic proceedings, 2013, Volume: 88, Issue:6

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Carnitine; Heart Failure; Humans; Myocardial Infarction; Odds

2013
The metabolic treatment of patients with coronary artery disease: effects on quality of life and effort angina.
    Current pharmaceutical design, 2009, Volume: 15, Issue:8

    Topics: Acetanilides; Angina Pectoris; Animals; Carnitine; Clinical Trials as Topic; Coronary Artery Disease

2009
Metabolic management of ischaemic heart disease.
    European heart journal, 1993, Volume: 14 Suppl G

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Carnitine; Ene

1993
[L-carnitine in the treatment of chronic myocardial ischemia. An analysis of 3 multicenter studies and a bibliographic review].
    La Clinica terapeutica, 1992, Volume: 140, Issue:4

    Topics: Angina Pectoris; Carnitine; Chronic Disease; Coronary Disease; Drug Evaluation; Germany; Humans; Ita

1992

Trials

13 trials available for carnitine and Angor Pectoris

ArticleYear
Effects of L-carnitine on exercise tolerance in patients with stable angina pectoris.
    Japanese heart journal, 1984, Volume: 25, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Electrocardiography; Exercise Test; Fatty A

1984
Intravenous dl-carnitine fails to increase the double-product during atrial pacing in patients with effort angina. A double-blind randomized study.
    Giornale italiano di cardiologia, 1983, Volume: 13, Issue:11

    Topics: Angina Pectoris; Cardiac Pacing, Artificial; Carnitine; Coronary Disease; Hemodynamics; Humans; Male

1983
Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris.
    The American journal of cardiology, 1994, Jul-15, Volume: 74, Issue:2

    Topics: Aged; Angina Pectoris; Cardiac Output; Cardiotonic Agents; Carnitine; Coronary Disease; Electrocardi

1994
Anti-ischaemic efficacy of L-propionylcarnitine--a promising novel metabolic approach to ischaemia?
    European heart journal, 1996, Volume: 17, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiotonic Agents; Cardiovascular Agents; Carnitine;

1996
Additional antiischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Carnitine; Exercise Test; Female; Humans; Male; Middle Aged; Myocardia

1995
L-carnitine moderately improves the exercise tolerance in chronic stable angina.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:11

    Topics: Adult; Analysis of Variance; Angina Pectoris; Carnitine; Chronic Disease; Drug Administration Schedu

2000
Controlled study on L-carnitine therapeutic efficacy in post-infarction.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Carnitine; Fe

1992
[L-carnitine in the treatment of chronic myocardial ischemia. An analysis of 3 multicenter studies and a bibliographic review].
    La Clinica terapeutica, 1992, Volume: 140, Issue:4

    Topics: Angina Pectoris; Carnitine; Chronic Disease; Coronary Disease; Drug Evaluation; Germany; Humans; Ita

1992
Propionyl-L-carnitine: a new compound in the metabolic approach to the treatment of effort angina.
    International journal of cardiology, 1992, Volume: 34, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Coronary Disease; Double-Blind Method; Exer

1992
The therapeutic effect of L-carnitine in patients with exercise-induced stable angina: a controlled study.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Diltiazem; Female; Humans; Male; Middle Age

1991
Propionyl carnitine in stable effort angina.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:2

    Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Double-Blind Method;

1990
Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo controlled crossover study.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:10

    Topics: Angina Pectoris; Blood Pressure; Carnitine; Clinical Trials as Topic; Double-Blind Method; Exercise

1985
[Effects of diltiazem and the combination diltiazem + L-carnitine in patients with exertion angina: a double-blind study with placebo].
    Cardiologia (Rome, Italy), 1985, Volume: 30, Issue:8

    Topics: Adult; Angina Pectoris; Benzazepines; Carnitine; Clinical Trials as Topic; Diltiazem; Double-Blind M

1985

Other Studies

10 other studies available for carnitine and Angor Pectoris

ArticleYear
Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris.
    Journal of the American Heart Association, 2017, 02-03, Volume: 6, Issue:2

    Topics: Aged; Angina Pectoris; Biomarkers; Carnitine; Cause of Death; Follow-Up Studies; Heart Arrest; Human

2017
A shift in myocardial substrate, improved endothelial function, and diminished sympathetic activity may contribute to the anti-anginal impact of very-low-fat diets.
    Medical hypotheses, 2004, Volume: 62, Issue:1

    Topics: Acetanilides; Angina Pectoris; Carnitine; Chemotherapy, Adjuvant; Diet, Fat-Restricted; Diet, Vegeta

2004
Effects of very low-fat diets on anginal symptoms.
    Medical hypotheses, 2004, Volume: 63, Issue:3

    Topics: Acetanilides; Angina Pectoris; Carnitine; Chemotherapy, Adjuvant; Diabetes Complications; Diabetes M

2004
The metabolical effects of L-carnitine in angina pectoris.
    International journal of cardiology, 1984, Volume: 5, Issue:2

    Topics: Angina Pectoris; Blood Glucose; Carnitine; Fatty Acids, Nonesterified; Humans; Lactates; Myocardium

1984
[Therapeutic application of myocardial cytoprotection].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1994, Volume: 13, Issue:9

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Carnitine; Hum

1994
Role of carnitine in fatty acid metabolism of normal and ischemic myocardium.
    American heart journal, 1979, Volume: 97, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Angina Pectoris; Atractyloside; Biological Transport; Carnitine;

1979
[The anti-angina action of carnitine].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Carnitine; Electrocardiography; Heart Rate; Humans; Ma

1978
Acute improvement of cardiac function with intravenous L-propionylcarnitine in humans.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:1

    Topics: Aged; Angina Pectoris; Blood Pressure; Carnitine; Coronary Disease; Female; Hemodynamics; Humans; In

1992
L-carnitine treatment for congestive heart failure--experimental and clinical study.
    Japanese circulation journal, 1992, Volume: 56, Issue:1

    Topics: Adult; Angina Pectoris; Animals; Cardiomyopathies; Carnitine; Chronic Disease; Cricetinae; Drug Eval

1992
Bicycle ergometer and echocardiographic study in healthy subjects and patients with angina pectoris after administration of L-carnitine: semiautomatic computerized analysis of M-mode tracing.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:4

    Topics: Adult; Angina Pectoris; Carnitine; Echocardiography; Exercise Test; Female; Humans; Male; Middle Age

1988