Page last updated: 2024-10-16

carnitine and Anemia, Cooley's

carnitine has been researched along with Anemia, Cooley's in 15 studies

Research Excerpts

ExcerptRelevanceReference
"Combination of hydroxyurea with l-carnitine or magnesium could be more effective in improving hematologic parameters and cardiac status in patients with beta-thalassemia intermedia than hydroxyurea alone."9.14Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. ( Amoozgar, H; Behmanesh, F; Borzouee, M; Haghpanah, S; Karimi, M; Mohammadi, F; Samani, SM, 2010)
"Carnitine is an essential protein for transportation of long-chain fatty acids to the matrix for beta-oxidation."6.78Determining and surveying the role of carnitine and folic acid to decrease fatigue in β-thalassemia minor subjects. ( Azimi, A; Hadaegh, A; Karimi, M; Mazloom, M; Shahriari, M; Tabei, SM; Zareifar, S, 2013)
"L-carnitine is an essential element of intermediary metabolism and also was shown to be effective in maintaining normal red blood cell (RBC) function."6.72L-carnitine deficiency and red blood cell mechanical impairment in beta-thalassemia major. ( Baskurt, OK; Baykal, A; Isbir, M; Kupesiz, A; Toptas, B; Yalcin, O; Yesilipek, A, 2006)
"Bone disease in beta-thalassemia major (betaTM) remains poorly understood."5.36Iron chelation therapy in Upper Egyptian transfusion-dependent pediatric homozygous beta-thalassemia major: impact on serum L-carnitine/free fatty acids, osteoprotegerin/the soluble receptor activator of nuclear factor-kappabeta ligand systems, and bone m ( El-Metwally, TH; Hamed, EA; Kamal, MM; Mohamed, NA, 2010)
"In total, 32 patients with beta-thalassemia major were recruited; 16 age- and sex-matched children constituted the control group."5.35Pulmonary hypertension in beta-thalassemia major and the role of L-carnitine therapy. ( El Accaoui, R; El-Beshlawy, A; El-Saidi, S; Makhlouf, A; Mansi, Y; Taher, A; Youssry, I, 2008)
"Combination of hydroxyurea with l-carnitine or magnesium could be more effective in improving hematologic parameters and cardiac status in patients with beta-thalassemia intermedia than hydroxyurea alone."5.14Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. ( Amoozgar, H; Behmanesh, F; Borzouee, M; Haghpanah, S; Karimi, M; Mohammadi, F; Samani, SM, 2010)
"Heart failure, fatal arrhythmias, and cardiac dilatation because of anemia are common causes of β-thalassemia major-related deaths."2.94The Effects of L-Carnitine on Echocardiographic Changes in Patients With β-Thalassemia Major and Intermedia. ( Fattahi, N; Hashemi, SR; Moradveisi, B; Roshani, D; Shahidi, M; Sharifi, P; Vahedi, S, 2020)
"Carnitine is an essential protein for transportation of long-chain fatty acids to the matrix for beta-oxidation."2.78Determining and surveying the role of carnitine and folic acid to decrease fatigue in β-thalassemia minor subjects. ( Azimi, A; Hadaegh, A; Karimi, M; Mazloom, M; Shahriari, M; Tabei, SM; Zareifar, S, 2013)
"Delayed puberty in beta-thalassemia major is either due to failure of gonads or failure of the whole hypothalamic pituitary gonadal axis."2.73Assessment of puberty in relation to L-carnitine and hormonal replacement therapy in beta-thalassemic patients. ( Abd El Dayem, SM; Abd El Ghafar, E; Aly, AA; El Beshlawy, A; El Sayed, MH; Farok, M; Mohtar, G, 2008)
"L-Carnitine plays an essential role in fatty acid beta-oxidation, a process especially important in the organs that preferentially use fatty acid as a source of energy such as the myocardium and the skeletal muscles."2.73Effect of L-carnitine on the physical fitness of thalassemic patients. ( Abd El-Sattar, M; El Accaoui, R; El-Beshlawy, A; El-Ghamrawy, M; Gamal El-Deen, MH; Hamdy, M; Shaheen, N; Taher, A; Youssry, I, 2007)
"L-carnitine is an essential element of intermediary metabolism and also was shown to be effective in maintaining normal red blood cell (RBC) function."2.72L-carnitine deficiency and red blood cell mechanical impairment in beta-thalassemia major. ( Baskurt, OK; Baykal, A; Isbir, M; Kupesiz, A; Toptas, B; Yalcin, O; Yesilipek, A, 2006)
"Excess iron deposition in patients with beta thalassemia major (BTM) causes excess free radical formation, damages the hypothalamic pituitary testicular axis and production of sperms with DNA defects."1.48A pilot study on sperm DNA damage in β-thalassemia major: is there a role for antioxidants? ( Ahmed, AY; Arafa, M; De Sanctis, V; Elalfy, MS; Elsedfy, H; Mohamed, NR, 2018)
"Mean carnitine was significantly lower (P=0."1.36L-carnitine in beta thalassemia. ( Jain, A; Kotian, M; Merchant, R; Puri, V; Udani, A, 2010)
"Bone disease in beta-thalassemia major (betaTM) remains poorly understood."1.36Iron chelation therapy in Upper Egyptian transfusion-dependent pediatric homozygous beta-thalassemia major: impact on serum L-carnitine/free fatty acids, osteoprotegerin/the soluble receptor activator of nuclear factor-kappabeta ligand systems, and bone m ( El-Metwally, TH; Hamed, EA; Kamal, MM; Mohamed, NA, 2010)
"In total, 32 patients with beta-thalassemia major were recruited; 16 age- and sex-matched children constituted the control group."1.35Pulmonary hypertension in beta-thalassemia major and the role of L-carnitine therapy. ( El Accaoui, R; El-Beshlawy, A; El-Saidi, S; Makhlouf, A; Mansi, Y; Taher, A; Youssry, I, 2008)
"In patients with homozygous beta thalassemia, the reduction of serum carnitine levels might play an important role in the appearance of muscular dysfunction."1.33Serum carnitine levels in patients with homozygous beta thalassemia: a possible new role for carnitine? ( Liapi-Adamidou, G; Tsagris, V, 2005)
"L-Carnitine seems to be a good modulator of apoptotic processes in thalassemic patients leading to a decreased frequency of programmed erythroblast death and general improvement of the disease condition."1.33Apoptosis in thalassemia major reduced by a butyrate derivative. ( Aoun, E; El-Beshlawy, A; Gabre, H; Ibrahim, A; Isma'eel, H; Seoud, H; Taher, A; Youssry, I, 2005)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's7 (46.67)29.6817
2010's5 (33.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Shahidi, M1
Hashemi, SR1
Fattahi, N1
Roshani, D1
Vahedi, S1
Sharifi, P1
Moradveisi, B1
Elsedfy, H1
De Sanctis, V1
Ahmed, AY1
Mohamed, NR1
Arafa, M1
Elalfy, MS1
Tabei, SM1
Mazloom, M1
Shahriari, M1
Zareifar, S1
Azimi, A1
Hadaegh, A1
Karimi, M2
El Beshlawy, A1
Mohtar, G1
Abd El Ghafar, E1
Abd El Dayem, SM1
El Sayed, MH1
Aly, AA1
Farok, M1
El-Beshlawy, A4
Youssry, I3
El-Saidi, S1
El Accaoui, R2
Mansi, Y1
Makhlouf, A2
Taher, A4
Merchant, R1
Jain, A1
Udani, A1
Puri, V1
Kotian, M1
Mohammadi, F1
Behmanesh, F1
Samani, SM1
Borzouee, M1
Amoozgar, H1
Haghpanah, S1
Hamed, EA1
Mohamed, NA1
El-Metwally, TH1
Kamal, MM1
Ragab, L1
Fattah, AA1
Ibrahim, IY1
Hamdy, M2
Aoun, E2
Hoffbrand, V1
Tsagris, V1
Liapi-Adamidou, G1
Seoud, H1
Ibrahim, A1
Gabre, H1
Isma'eel, H1
Toptas, B1
Baykal, A1
Yesilipek, A1
Isbir, M1
Kupesiz, A1
Yalcin, O1
Baskurt, OK1
Abd El-Sattar, M1
Gamal El-Deen, MH1
Shaheen, N1
El-Ghamrawy, M1
Palmieri, L1
Ronca, F1
Malengo, S1
Bertelli, A1
Yeşilipek, MA1
Hazar, V1
Yegin, O1

Trials

7 trials available for carnitine and Anemia, Cooley's

ArticleYear
The Effects of L-Carnitine on Echocardiographic Changes in Patients With β-Thalassemia Major and Intermedia.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:6

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; beta-Thalassemia; Carnitine; Case-Control Studies; Child; C

2020
Determining and surveying the role of carnitine and folic acid to decrease fatigue in β-thalassemia minor subjects.
    Pediatric hematology and oncology, 2013, Volume: 30, Issue:8

    Topics: Adolescent; beta-Thalassemia; Carnitine; Child; Child, Preschool; Dietary Supplements; Fatigue; Fema

2013
Assessment of puberty in relation to L-carnitine and hormonal replacement therapy in beta-thalassemic patients.
    Journal of tropical pediatrics, 2008, Volume: 54, Issue:6

    Topics: Adolescent; Adult; beta-Thalassemia; Carnitine; Estrogens; Female; Follow-Up Studies; Hormone Replac

2008
Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia.
    European journal of haematology, 2010, Jan-01, Volume: 84, Issue:1

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Urea Nitrogen; Carnitine; Child; Child, Preschool; Creati

2010
Improvement of cardiac function in thalassemia major treated with L-carnitine.
    Acta haematologica, 2004, Volume: 111, Issue:3

    Topics: Adolescent; Adult; Angiography; beta-Thalassemia; Carnitine; Child; Electrocardiography; Female; Hea

2004
L-carnitine deficiency and red blood cell mechanical impairment in beta-thalassemia major.
    Clinical hemorheology and microcirculation, 2006, Volume: 35, Issue:3

    Topics: Adolescent; beta-Thalassemia; Calcium; Carnitine; Child; Child, Preschool; Dietary Supplements; Eryt

2006
Effect of L-carnitine on the physical fitness of thalassemic patients.
    Annals of hematology, 2007, Volume: 86, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Carnitine; Child; Comb

2007

Other Studies

8 other studies available for carnitine and Anemia, Cooley's

ArticleYear
A pilot study on sperm DNA damage in β-thalassemia major: is there a role for antioxidants?
    Acta bio-medica : Atenei Parmensis, 2018, 03-27, Volume: 89, Issue:1

    Topics: Acetylcysteine; Adult; Antioxidants; beta-Thalassemia; Carnitine; DNA Damage; DNA Fragmentation; Hum

2018
Pulmonary hypertension in beta-thalassemia major and the role of L-carnitine therapy.
    Pediatric hematology and oncology, 2008, Volume: 25, Issue:8

    Topics: Administration, Oral; Adolescent; beta-Thalassemia; Carnitine; Case-Control Studies; Child; Child, P

2008
L-carnitine in beta thalassemia.
    Indian pediatrics, 2010, Volume: 47, Issue:2

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Carnitine; Case-Control Studies; Child; Diet

2010
Iron chelation therapy in Upper Egyptian transfusion-dependent pediatric homozygous beta-thalassemia major: impact on serum L-carnitine/free fatty acids, osteoprotegerin/the soluble receptor activator of nuclear factor-kappabeta ligand systems, and bone m
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:4

    Topics: beta-Thalassemia; Blood Transfusion; Bone Density; Carnitine; Case-Control Studies; Chelation Therap

2010
Serum carnitine levels in patients with homozygous beta thalassemia: a possible new role for carnitine?
    European journal of pediatrics, 2005, Volume: 164, Issue:3

    Topics: Adolescent; Adult; beta-Thalassemia; Carnitine; Case-Control Studies; Child; Child, Preschool; Fatty

2005
Apoptosis in thalassemia major reduced by a butyrate derivative.
    Acta haematologica, 2005, Volume: 114, Issue:3

    Topics: Adolescent; Apoptosis; beta-Thalassemia; Bone Marrow Cells; Carnitine; Child; Child, Preschool; DNA

2005
Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine.
    International journal of tissue reactions, 1994, Volume: 16, Issue:3

    Topics: Adult; beta-Thalassemia; Carnitine; Erythrocytes; Female; Humans; Male; Middle Aged; Oxidative Stres

1994
L-Carnitine treatment in beta thalassemia major.
    Acta haematologica, 1998, Volume: 100, Issue:3

    Topics: Adolescent; Adult; beta-Thalassemia; Carnitine; Child; Child, Preschool; Female; Humans; Male

1998