carnitine has been researched along with Alloxan Diabetes in 144 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The important pathological consequences of insulin resistance arise from the detrimental effects of accumulated long-chain fatty acids and their respective acylcarnitines." | 7.83 | Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. ( Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Svalbe, B; Volska, K, 2016) |
| "To compare the effects of combined and individual supplementation of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats." | 7.79 | Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats. ( Ahmad, T; Anwar, MK; Hussain, MM; Khan, MA, 2013) |
| "Rats with streptozotocin-induced diabetes (STZ-D) have reduced serum carnitine levels and bradycardia." | 7.74 | Diabetes-induced bradycardia is an intrinsic metabolic defect reversed by carnitine. ( Hanna, SK; Liang, X; Malone, JI; Malone, MA; Schocken, DD, 2007) |
| " Plasma levels of glucose, insulin, malondialdehyde and antioxidants such as reduced glutathione, catalase and superoxide dismutase, haemoglobin A1c (HbA1c), insulin sensitivity index (ISI) as well as the contractile properties of the gastrocnemius muscle were measured." | 3.88 | Effect of L-carnitine on diabetes-induced changes of skeletal muscles in rats. ( Abbas, AM; Elserougy, HG; Safwat, SM; Samir, SM, 2018) |
| "The important pathological consequences of insulin resistance arise from the detrimental effects of accumulated long-chain fatty acids and their respective acylcarnitines." | 3.83 | Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. ( Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Svalbe, B; Volska, K, 2016) |
| "To compare the effects of combined and individual supplementation of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats." | 3.79 | Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats. ( Ahmad, T; Anwar, MK; Hussain, MM; Khan, MA, 2013) |
| "Rats with streptozotocin-induced diabetes (STZ-D) have reduced serum carnitine levels and bradycardia." | 3.74 | Diabetes-induced bradycardia is an intrinsic metabolic defect reversed by carnitine. ( Hanna, SK; Liang, X; Malone, JI; Malone, MA; Schocken, DD, 2007) |
| " Response of myocardial function to rapid intravenous infusion of saline 10 mL/kg/min and the times of onset of ventricular arrhythmias during intravenous infusion of aconitine 20 micrograms/kg/min were determined in anesthetized rats at week 12." | 3.69 | Cardiovascular and metabolic changes in spontaneously hypertensive rats following streptozotocin administration. ( Battell, M; Dai, S; Lee, S; McNeill, JH, 1994) |
| "Concentrations of vitamins, biopterin, free inositol and acid-soluble carnitine were determined in cyclosporine A induced renal adenocarcinoma and uninvaded renal tissue from streptozotocin diabetic rats." | 3.68 | Vitamin and micronutrient concentrations in cyclosporine-induced renal tumor from diabetic rats. ( Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Kabaria, V; Reddi, AS, 1991) |
| "The effect of intraperitoneally administered carnitine (10 or 100 mg/kg) on the early stage of liver regeneration after two-third hepatectomy was studied in rats with experimentally induced alloxan diabetes (60 mg/kg IV)." | 3.68 | [The effect of carnitine on the early phase of liver regeneration after partial hepatectomy in rats with experimental diabetes]. ( Cervinková, Z; Kalinová, M; Simek, J, 1992) |
| "The enhancement of long-chain fatty acid oxidation and ketogenesis in the perfused rat liver, whether induced acutely by treatment of fed animals with anti-insulin serum or glucagon, or over the longer term by starvation or the induction of alloxan diabetes, was found to ba accompanied by a proportional elevation in the tissue carnitine content." | 3.65 | Role of carnitine in hepatic ketogenesis. ( Foster, DW; McGarry, JD; Robles-Valdes, C, 1975) |
| "Carnitine insufficiency is reported in type 1 diabetes mellitus." | 1.62 | The Effects of Streptozotocin-Induced Diabetes and Insulin Treatment on Carnitine Biosynthesis and Renal Excretion. ( Boyle, KE; Broderick, TL; Upadhyay, A, 2021) |
| "L-carnitine (LC) has many beneficial effects on diabetic animals and humans, but its regulatory effect on chemerin as an inflammatory cytokine, and its receptor in diabetes status is unknown." | 1.62 | Novel Cardioprotective Effect of L-Carnitine on Obese Diabetic Mice: Regulation of Chemerin and CMKLRI Expression in Heart and Adipose Tissues. ( Amiri, R; Hosseini, SA; Tabandeh, MR, 2021) |
| "L‑carnitine (LC) was recently demonstrated to serve a positive role in ameliorating DPN." | 1.51 | L-carnitine ameliorates peripheral neuropathy in diabetic mice with a corresponding increase in insulin‑like growth factor‑1 level. ( Dong, J; Liu, Y; Ma, R; Song, L; Wang, L; Wang, R; Zhang, C; Zhang, Y, 2019) |
| "The pathogenesis of diabetic kidney disease is complex, and fundamental research is still required to provide a better understanding of the driving forces behind it." | 1.51 | Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging. ( Bergman, HM; Kihlberg, J; Lanekoff, I; Lindfors, L; Palm, F, 2019) |
| "L-carnitine has been shown to enhance wound healing." | 1.40 | Effect of systemic carnitine therapy on serum fibronectin level in diabetic rats. ( Arslan, E; Aşık, M; Kemik, AS; Kömürcü, E; Nusran, G; Özkan, ÖF, 2014) |
| "To investigate the protective effect of L-carnitine (LC) combined with sildenafil on the reproductive endocrine function of male rats with diabetes mellitus (DM)." | 1.38 | [Protective effect of L-carnitine combined with sildenafil on the reproductive endocrine function of diabetic male rats]. ( Cui, YX; Huang, YF; Kang, N; Shang, XJ; Shi, ZR; Xia, XY; Zhan, XX, 2012) |
| "l-Carnitine treatment also prevented decreased mRNA expressions of nephrin and podocin in the high glucose-stimulated podocytes." | 1.36 | Ameliorating effects of L-carnitine on diabetic podocyte injury. ( Fan, JP; Ha, TS; Han, GD; Kawachi, H; Kim, D, 2010) |
| "L-carnitine treatment restored the hyporesponsiveness of isoprenaline and the hyperresponsiveness of adenosine-elicited relaxation." | 1.35 | L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats. ( Gur, S; Irat, AM, 2008) |
| "As L-carnitine plays a pivotal role in the balanced metabolism of fatty acids and carbohydrates, this study was carried out to investigate whether long-term mildronate treatment could influence glucose levels and prevent diabetic complications in an experimental model of type 2 diabetes in Goto-Kakizaki (GK) rats." | 1.35 | Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats. ( Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Skapare, E; Svalbe, B; Vilskersts, R; Zvejniece, L, 2009) |
| " From the above findings, it is evident that STZ-diabetes has an adverse effect on sperm maturation, which may be due to the decrease in the bioavailability of testosterone and epididymal secretory products." | 1.35 | Impact of experimental diabetes and insulin replacement on epididymal secretory products and sperm maturation in albino rats. ( Balasubramanian, K; Malini, T; Rengarajan, S; Singh, S, 2009) |
| "Betaine levels were found to be increased in the majority of diabetic mice but decreased in a few animals with severe loss of body weight and physical condition." | 1.35 | Metabolic profile changes in the testes of mice with streptozotocin-induced type 1 diabetes mellitus. ( Agbaje, IM; Amigues, E; Browne, RA; Green, BD; Hollis, J; Mallidis, C; McClure, N; Migaud, M; Rogers, D, 2009) |
| "L-carnitine is a naturally compound widely distributed in the body." | 1.33 | Effect of L-carnitine on diabetogenic action of streptozotocin in rats. ( Acikgoz, O; Gonenc, S; Kayatekin, BM; Uysal, N; Yalaz, G, 2005) |
| "L-Carnitine was supplemented by IM injection of 100 mg/kg per day for 10 days." | 1.32 | Short term effects of L-carnitine on serum lipids in STZ-induced diabetic rats. ( Atik, U; Cimen, MY; Eskandari, HG; Kanik, A; Tamer, L, 2004) |
| "L-Carnitine treatment completely normalized plasma cholesterol, triglyceride, free carnitine and TBARS levels but partially restored blood glucose levels of diabetic rats." | 1.32 | Effects of L-carnitine treatment on oxidant/antioxidant state and vascular reactivity of streptozotocin-diabetic rat aorta. ( Aktan, F; Irat, AM; Ozansoy, G, 2003) |
| "L-Carnitine treatment of diabetic rats had no effect on the levels of IGF-II in serum, liver, and kidney." | 1.31 | L-Carnitine changes the levels of insulin-like growth factors (IGFs) and IGF binding proteins in streptozotocin-induced diabetic rat. ( Cha, YS; Heo, YR; Kang, CW, 2001) |
| " In conclusion, this study suggests that short-term administration of LA at high dosage to normal and diabetic rats causes an inhibition of gluconeogenesis secondary to an interference with hepatic fatty acid oxidation." | 1.30 | Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats. ( Bashan, N; Gutman, A; Khamaisi, M; Potashnik, R; Rudich, A; Tritschler, HJ, 1999) |
| "L-carnitine treatment stimulated glucose oxidation during reperfusion in control and diabetic rat hearts." | 1.29 | L-carnitine increases glucose metabolism and mechanical function following ischaemia in diabetic rat heart. ( Broderick, TL; Lopaschuk, GD; Quinney, HA, 1995) |
| "Carnitine deficiency has been demonstrated in diabetic hearts, and it is also well known that L-carnitine administration has a beneficial effect on cardiac function." | 1.29 | Changes in the subcellular distribution of free carnitine and its acyl derivatives in diabetic rat hearts following treatment with L-carnitine. ( Aoshima, S; Fujisawa, S; Kobayashi, A, 1993) |
| "Myo-inositol concentration was decreased in liver, heart and kidney but not in brain, pancreas and skeletal muscle." | 1.28 | Effect of short- and long-term diabetes on carnitine and myo-inositol in rats. ( Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Reddi, AS, 1991) |
| "L-Propionylcarnitine treatment of the diabetic rats partially normalized these activities." | 1.28 | Na(+)-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats. ( Dhalla, NS; Ferrari, R; Pierce, GN; Ramjiawan, B, 1990) |
| "Free inositol content was highest in brain and lowest in skeletal muscle of CBL and db/db mice; diabetes or ETOH intake did not affect tissue inositol content." | 1.28 | Effect of genetic diabetes and alcohol on tissue carnitine and inositol concentrations in mice. ( Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Leevy, CB; Reddi, AS, 1990) |
| "L-carnitine treatment to diabetic rats significantly reduced serum glucose, FFA, triglycerides, and ketones." | 1.27 | Improvement of myocardial function in diabetic rats after treatment with L-carnitine. ( Paulson, DJ; Ramacci, MT; Schmidt, MJ; Shug, AL; Traxler, JS, 1984) |
| "L-Carnitine treatment of the diabetic rats increased myocardial free-carnitine levels, which were comparable with those of control rats." | 1.27 | Effect of L-carnitine treatment on lipid metabolism and cardiac performance in chronically diabetic rats. ( McNeill, JH; Rodrigues, B; Xiang, H, 1988) |
| "Aminocarnitine has a strong hypoglycemic effect in fasted diabetic mice; a single dose (0." | 1.27 | Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines. ( Griffith, OW; Jenkins, DL, 1986) |
| " Drug-treated animals had significant lowering of fasting glucose at 0 and 4 h after dosing during the midportion of the study (2-6 wk)." | 1.26 | Metabolic control of prevention of nephropathy by 2-tetradecylglycidate in the diabetic mouse (db/db). ( Bressler, R; Kircher, CH; Lee, SM; Tutwiler, G, 1982) |
| "Carnitine transport was enhanced by the perfusion with palmitate." | 1.26 | A mechanism for reduced myocardial carnitine levels in diabetic animals. ( Neely, JR; Vary, TC, 1982) |
| "Carnitine dependence was enhanced at lower concentrations of [(14)C]palmitate." | 1.26 | [14C]palmitate uptake in isolated rat liver mitochondria: effects of fasting, diabetes mellitus, and inhibitors of carnitine acyltransferase. ( Amatruda, JM; Kiesow, LA; Lockwood, DH; Margolis, S, 1978) |
| "4." | 1.25 | Relationships between carnitine and coenzyme A esters in tissues of normal and alloxan-diabetic sheep. ( Koundakjian, PP; Snoswell, AM, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (38.19) | 18.7374 |
| 1990's | 40 (27.78) | 18.2507 |
| 2000's | 22 (15.28) | 29.6817 |
| 2010's | 19 (13.19) | 24.3611 |
| 2020's | 8 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| van Liempd, S | 1 |
| Cabrera, D | 1 |
| Pilzner, C | 1 |
| Kollmus, H | 1 |
| Schughart, K | 1 |
| Falcón-Pérez, JM | 1 |
| Amiri, R | 1 |
| Tabandeh, MR | 2 |
| Hosseini, SA | 1 |
| Upadhyay, A | 1 |
| Boyle, KE | 1 |
| Broderick, TL | 9 |
| Dzugkoev, SG | 1 |
| Dzugkoeva, FS | 1 |
| Margieva, OI | 1 |
| Khubulova, AE | 1 |
| Majidi, FZ | 1 |
| Rezaei, N | 1 |
| Zare, Z | 1 |
| Dashti, A | 1 |
| Shafaroudi, MM | 1 |
| Abediankenari, S | 1 |
| Ranjbar Kohan, N | 1 |
| Nazifi, S | 1 |
| Soleimani, Z | 1 |
| Hanafy, MM | 1 |
| Lindeque, JZ | 1 |
| El-Maraghy, SA | 1 |
| Abdel-Hamid, AZ | 1 |
| Shahin, NN | 1 |
| Li, XF | 1 |
| Shi, ZD | 1 |
| Song, H | 1 |
| Wang, YL | 1 |
| Li, QC | 1 |
| Diao, XH | 1 |
| Pang, YW | 1 |
| Zhou, SH | 1 |
| Liu, HY | 1 |
| Xiang, L | 1 |
| Wei, J | 1 |
| Tian, XY | 1 |
| Wang, B | 1 |
| Chan, W | 1 |
| Li, S | 1 |
| Tang, Z | 1 |
| Zhang, H | 1 |
| Cheang, WS | 1 |
| Zhao, Q | 1 |
| Zhao, H | 1 |
| Yang, Z | 1 |
| Hong, Y | 1 |
| Huang, Y | 1 |
| Cai, Z | 1 |
| Samir, SM | 1 |
| Abbas, AM | 2 |
| Safwat, SM | 1 |
| Elserougy, HG | 1 |
| Wang, R | 1 |
| Wang, L | 1 |
| Zhang, C | 1 |
| Zhang, Y | 1 |
| Liu, Y | 1 |
| Song, L | 1 |
| Ma, R | 1 |
| Dong, J | 1 |
| Bergman, HM | 1 |
| Lindfors, L | 1 |
| Palm, F | 1 |
| Kihlberg, J | 1 |
| Lanekoff, I | 1 |
| Anwar, MK | 1 |
| Hussain, MM | 2 |
| Khan, MA | 1 |
| Ahmad, T | 1 |
| Kömürcü, E | 1 |
| Özkan, ÖF | 1 |
| Kemik, AS | 1 |
| Nusran, G | 1 |
| Aşık, M | 1 |
| Arslan, E | 1 |
| ElGendy, AA | 1 |
| Sleem, M | 1 |
| Taye, A | 1 |
| El-Moselhy, MA | 1 |
| Mangoura, SA | 1 |
| Giesbertz, P | 1 |
| Ecker, J | 1 |
| Haag, A | 1 |
| Spanier, B | 1 |
| Daniel, H | 1 |
| Minkler, PE | 1 |
| Stoll, MS | 1 |
| Ingalls, ST | 1 |
| Kerner, J | 1 |
| Hoppel, CL | 1 |
| Freeman, OJ | 1 |
| Unwin, RD | 1 |
| Dowsey, AW | 1 |
| Begley, P | 1 |
| Ali, S | 1 |
| Hollywood, KA | 1 |
| Rustogi, N | 1 |
| Petersen, RS | 1 |
| Dunn, WB | 1 |
| Cooper, GJ | 1 |
| Gardiner, NJ | 1 |
| Ruiz, M | 1 |
| Coderre, L | 1 |
| Lachance, D | 1 |
| Houde, V | 1 |
| Martel, C | 1 |
| Thompson Legault, J | 1 |
| Gillis, MA | 1 |
| Bouchard, B | 1 |
| Daneault, C | 1 |
| Carpentier, AC | 1 |
| Gaestel, M | 1 |
| Allen, BG | 1 |
| Des Rosiers, C | 1 |
| Liepinsh, E | 2 |
| Makrecka-Kuka, M | 1 |
| Makarova, E | 1 |
| Volska, K | 1 |
| Svalbe, B | 2 |
| Sevostjanovs, E | 1 |
| Grinberga, S | 2 |
| Kuka, J | 2 |
| Dambrova, M | 2 |
| Salmanoglu, DS | 1 |
| Gurpinar, T | 1 |
| Vural, K | 1 |
| Ekerbicer, N | 1 |
| Darıverenli, E | 1 |
| Var, A | 1 |
| Gur, S | 1 |
| Irat, AM | 2 |
| Vilskersts, R | 1 |
| Zvejniece, L | 1 |
| Skapare, E | 1 |
| Cirule, H | 1 |
| Kalvinsh, I | 1 |
| Mynatt, RL | 2 |
| Singh, S | 1 |
| Malini, T | 1 |
| Rengarajan, S | 1 |
| Balasubramanian, K | 1 |
| Shaker, ME | 1 |
| Houssen, ME | 1 |
| Abo-Hashem, EM | 1 |
| Ibrahim, TM | 1 |
| Fan, JP | 1 |
| Kim, D | 1 |
| Kawachi, H | 1 |
| Ha, TS | 1 |
| Han, GD | 1 |
| Kang, N | 2 |
| Ma, JH | 1 |
| Zhou, X | 1 |
| Fan, XB | 1 |
| Shang, XJ | 2 |
| Huang, YF | 2 |
| Meissner, M | 1 |
| Herrema, H | 1 |
| van Dijk, TH | 1 |
| Gerding, A | 1 |
| Havinga, R | 1 |
| Boer, T | 1 |
| Müller, M | 1 |
| Reijngoud, DJ | 1 |
| Groen, AK | 1 |
| Kuipers, F | 1 |
| Shi, ZR | 1 |
| Zhan, XX | 1 |
| Xia, XY | 1 |
| Cui, YX | 1 |
| Bin Aleem, S | 1 |
| Farooq, Y | 1 |
| Giannessi, F | 1 |
| Pessotto, P | 2 |
| Tassoni, E | 1 |
| Chiodi, P | 1 |
| Conti, R | 1 |
| De Angelis, F | 1 |
| Dell'Uomo, N | 1 |
| Catini, R | 1 |
| Deias, R | 1 |
| Tinti, MO | 1 |
| Carminati, P | 1 |
| Arduini, A | 2 |
| Aktan, F | 1 |
| Ozansoy, G | 1 |
| Paulson, DJ | 7 |
| Gillis, M | 2 |
| Eskandari, HG | 1 |
| Cimen, MY | 1 |
| Tamer, L | 1 |
| Kanik, A | 1 |
| Atik, U | 1 |
| Su, X | 1 |
| Han, X | 1 |
| Mancuso, DJ | 1 |
| Abendschein, DR | 1 |
| Gross, RW | 1 |
| Uysal, N | 1 |
| Yalaz, G | 1 |
| Acikgoz, O | 1 |
| Gonenc, S | 1 |
| Kayatekin, BM | 1 |
| Malone, JI | 2 |
| Cuthbertson, DD | 1 |
| Malone, MA | 2 |
| Schocken, DD | 2 |
| Kato, H | 1 |
| Power, RA | 1 |
| Hulver, MW | 1 |
| Zhang, JY | 1 |
| Dubois, J | 1 |
| Marchand, RM | 1 |
| Ilkayeva, O | 1 |
| Muoio, DM | 1 |
| Hanna, SK | 1 |
| Liang, X | 1 |
| Mallidis, C | 1 |
| Green, BD | 1 |
| Rogers, D | 1 |
| Agbaje, IM | 1 |
| Hollis, J | 1 |
| Migaud, M | 1 |
| Amigues, E | 1 |
| McClure, N | 1 |
| Browne, RA | 1 |
| Lopaschuk, GD | 5 |
| Tahiliani, AG | 3 |
| Vadlamudi, RV | 1 |
| Katz, S | 4 |
| McNeill, JH | 11 |
| Stearns, SB | 2 |
| Eibschutz, B | 1 |
| Henderson, GD | 2 |
| Xue, GP | 1 |
| Snoswell, AM | 5 |
| Pieper, GM | 3 |
| Murray, WJ | 3 |
| Salhany, JM | 2 |
| Wu, ST | 2 |
| Eliot, RS | 2 |
| Schmidt, MJ | 1 |
| Traxler, JS | 1 |
| Ramacci, MT | 1 |
| Shug, AL | 3 |
| Neely, JR | 3 |
| Robishaw, JD | 1 |
| Vary, TC | 2 |
| Lee, SM | 1 |
| Tutwiler, G | 1 |
| Bressler, R | 2 |
| Kircher, CH | 1 |
| Stevens, MJ | 1 |
| Feldman, EL | 1 |
| Greene, DA | 1 |
| Cotter, MA | 3 |
| Cameron, NE | 3 |
| Keegan, A | 1 |
| Dines, KC | 1 |
| Quinney, HA | 1 |
| Christe, ME | 1 |
| Rodgers, RL | 1 |
| Ido, Y | 1 |
| McHowat, J | 1 |
| Chang, KC | 1 |
| Arrigoni-Martelli, E | 2 |
| Orfalian, Z | 1 |
| Kilo, C | 1 |
| Corr, PB | 1 |
| Williamson, JR | 1 |
| Dai, S | 1 |
| Lee, S | 1 |
| Battell, M | 1 |
| Aoshima, S | 1 |
| Fujisawa, S | 1 |
| Kobayashi, A | 1 |
| Marzo, A | 1 |
| Corsico, N | 2 |
| Cardace, G | 1 |
| Morabito, E | 2 |
| Hotta, N | 5 |
| Koh, N | 5 |
| Sakakibara, F | 4 |
| Nakamura, J | 5 |
| Hamada, Y | 3 |
| Wakao, T | 1 |
| Hara, T | 4 |
| Mori, K | 1 |
| Naruse, K | 2 |
| Nakashima, E | 3 |
| Sakamoto, N | 3 |
| Hamara, Y | 1 |
| Sasaki, H | 2 |
| Fukasawa, H | 2 |
| Kakuta, H | 2 |
| Dottori, S | 1 |
| Sciarroni, AF | 1 |
| Calvani, M | 2 |
| Haloftis, G | 1 |
| Schmitz, FJ | 2 |
| Rösen, P | 2 |
| Reinauer, H | 2 |
| Yildiz, O | 2 |
| Ozata, M | 2 |
| Ozkardeş, A | 2 |
| Deniz, G | 1 |
| Yildirimkaya, M | 1 |
| Corakçi, A | 2 |
| Yardim, M | 1 |
| Gündoğan, MA | 2 |
| Xu, Z | 1 |
| Patel, KP | 1 |
| Rozanski, GJ | 1 |
| Gündoğan, N | 1 |
| Liberati, R | 1 |
| Petrella, O | 1 |
| Romanelli, L | 1 |
| Peluso, G | 1 |
| Abdel-aleem, S | 1 |
| Karim, AM | 1 |
| Zarouk, WA | 1 |
| Taylor, DA | 1 |
| el-Awady, MK | 1 |
| Lowe, JE | 1 |
| Terada, R | 1 |
| Matsubara, T | 1 |
| Chaya, S | 1 |
| Komori, T | 1 |
| Kato, K | 1 |
| Takeuchi, N | 1 |
| Kasuya, Y | 1 |
| Keller, VA | 1 |
| Toporoff, B | 1 |
| Raziano, RM | 1 |
| Pigott, JD | 1 |
| Mills, NL | 1 |
| Khamaisi, M | 1 |
| Rudich, A | 1 |
| Potashnik, R | 1 |
| Tritschler, HJ | 1 |
| Gutman, A | 1 |
| Bashan, N | 1 |
| Driedzic, W | 1 |
| Hayashi, K | 1 |
| Okumura, K | 1 |
| Matsui, H | 1 |
| Murase, K | 1 |
| Kamiya, H | 1 |
| Saburi, Y | 1 |
| Numaguchi, Y | 1 |
| Toki, Y | 1 |
| Hayakawa, T | 1 |
| Felix, C | 1 |
| Driedzic, WR | 1 |
| Heo, YR | 1 |
| Kang, CW | 1 |
| Cha, YS | 1 |
| Akisu, M | 1 |
| Kultursay, N | 1 |
| Coker, I | 1 |
| Huseyinov, A | 1 |
| Costa, ND | 1 |
| Amatruda, JM | 1 |
| Lockwood, DH | 1 |
| Margolis, S | 1 |
| Kiesow, LA | 1 |
| Macnab, M | 1 |
| Goldberg, RB | 1 |
| Joffe, BI | 1 |
| Botha, A | 1 |
| Seftel, HC | 1 |
| Fogle, PJ | 1 |
| Bieber, LL | 1 |
| Kerbey, AL | 1 |
| Randle, PJ | 1 |
| Cooper, RH | 1 |
| Whitehouse, S | 1 |
| Pask, HT | 1 |
| Denton, RM | 1 |
| Parvin, R | 1 |
| Pande, SV | 1 |
| Sinclair-Smith, BC | 1 |
| Paul, HS | 1 |
| Adibi, SA | 1 |
| Liu, MS | 1 |
| Spitzer, JJ | 1 |
| Feuvray, D | 2 |
| Idell-Wenger, JA | 1 |
| McGarry, JD | 2 |
| Robles-Valdes, C | 1 |
| Foster, DW | 2 |
| Duan, RD | 1 |
| Cheng, Y | 1 |
| Erlanson-Albertsson, C | 1 |
| Pasini, E | 1 |
| Comini, L | 1 |
| Ferrari, R | 2 |
| de Giuli, F | 1 |
| Menotti, A | 1 |
| Dhalla, NS | 3 |
| Reddi, AS | 4 |
| Jyothirmayi, GN | 4 |
| Leevy, CB | 2 |
| Khalil, M | 1 |
| DeAngelis, B | 4 |
| Frank, O | 4 |
| Baker, H | 4 |
| Cervinková, Z | 1 |
| Kalinová, M | 1 |
| Simek, J | 1 |
| Zhao, J | 1 |
| Elimban, V | 1 |
| Rupp, H | 1 |
| Kabaria, V | 1 |
| Rodrigues, B | 4 |
| Seccombe, D | 1 |
| St-Laurent, R | 2 |
| Rousseau-Migneron, S | 3 |
| Tancrede, G | 3 |
| Nadeau, A | 3 |
| Pierce, GN | 1 |
| Ramjiawan, B | 1 |
| Adrian, M | 1 |
| Ross, JR | 1 |
| Farahbakshian, S | 1 |
| Dillmann, WH | 1 |
| Xiang, H | 2 |
| Wernette-Hammond, ME | 1 |
| Lardy, HA | 1 |
| Okuda, Y | 1 |
| Kawai, K | 1 |
| Yamashita, K | 1 |
| Kopp, SJ | 1 |
| Peace, DG | 1 |
| Tow, JP | 1 |
| Jenkins, DL | 1 |
| Griffith, OW | 1 |
| Sandor, A | 1 |
| Kispal, G | 1 |
| Melegh, B | 1 |
| Alkonyi, I | 1 |
| Hekimian, G | 1 |
| Brooks, SD | 1 |
| Bahl, JJ | 1 |
| Brosnan, JT | 1 |
| Reid, K | 1 |
| Osmundsen, H | 1 |
| Bjørnstad, K | 1 |
| Norum, KR | 1 |
| Harano, Y | 1 |
| Kowal, J | 1 |
| Yamazaki, R | 1 |
| Lavine, L | 1 |
| Miller, M | 1 |
| Mackerer, CR | 1 |
| Mehlman, MA | 3 |
| Tobin, RB | 2 |
| Lerner, E | 1 |
| Elson, C | 1 |
| Shrago, E | 1 |
| McIntosh, GH | 1 |
| Huth, W | 1 |
| Dierich, C | 1 |
| von Oeynhausen, V | 1 |
| Seubert, W | 1 |
| Koundakjian, PP | 1 |
| Sauer, F | 1 |
| Erfle, JD | 1 |
| Binns, MR | 1 |
| Therriault, DG | 2 |
| Daikuhara, Y | 1 |
| Tsunemi, T | 1 |
| Takeda, Y | 1 |
| Kader, MM | 1 |
| Krebs, HA | 1 |
| Wallace, PG | 1 |
| Hems, R | 1 |
| Freedland, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for carnitine and Alloxan Diabetes
| Article | Year |
|---|---|
Carnitine and type 2 diabetes.
Topics: Acyl Coenzyme A; Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Die | 2009 |
The aetiology of diabetic neuropathy: the combined roles of metabolic and vascular defects.
Topics: Aldehyde Reductase; Animals; Carnitine; Cells; Diabetes Mellitus; Diabetes Mellitus, Experimental; D | 1995 |
Paradoxical role of lipid metabolism in heart function and dysfunction.
Topics: Adenosine Triphosphatases; Animals; Carnitine; Diabetes Complications; Diabetes Mellitus; Diabetes M | 1992 |
Diabetes-induced abnormalities in the myocardium.
Topics: Adenosine Triphosphatases; Animals; Blood Glucose; Calcium; Carbohydrate Metabolism; Cardiomyopathie | 1986 |
Diabetes mellitus and hypothyroidism induce changes in myosin isoenzyme distribution in the rat heart--do alterations in fuel flux mediate these changes?
Topics: Adenosine Triphosphatases; Animals; Carnitine; Diabetes Mellitus, Experimental; Energy Metabolism; H | 1986 |
Carnitine derivatives are antiketogenic and hypoglycemic agents.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Ketone Bodies; Mice | 1986 |
138 other studies available for carnitine and Alloxan Diabetes
| Article | Year |
|---|---|
Impaired beta-oxidation increases vulnerability to influenza A infection.
Topics: Amino Acids, Branched-Chain; Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2021 |
Novel Cardioprotective Effect of L-Carnitine on Obese Diabetic Mice: Regulation of Chemerin and CMKLRI Expression in Heart and Adipose Tissues.
Topics: Animals; Carnitine; Chemokines; Diabetes Mellitus, Experimental; Intercellular Signaling Peptides an | 2021 |
The Effects of Streptozotocin-Induced Diabetes and Insulin Treatment on Carnitine Biosynthesis and Renal Excretion.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hypoglycemic Agents; | 2021 |
Analysis of Mechanisms Underlying the Development of Endothelial Dysfunction and Functional Disorders in Experimental Diabetes Mellitus and Their Pathogenetic Correction.
Topics: Animals; Arginine; Carnitine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Humans; Nitric | 2023 |
The Protective Effects of L-Carnitine and Zinc Oxide Nanoparticles Against Diabetic Injury on Sex Steroid Hormones Levels, Oxidative Stress, and Ovarian Histopathological Changes in Rat.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Female | 2021 |
L-carnitine improves metabolic disorders and regulates apelin and apelin receptor genes expression in adipose tissue in diabetic rats.
Topics: Adipose Tissue; Animals; Apelin; Apelin Receptors; Blood Glucose; Carnitine; Diabetes Mellitus, Expe | 2020 |
Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.
Topics: Animals; Biomarkers; Carnitine; Cluster Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Dis | 2021 |
Protective effects of L-carnitine on reproductive capacity in rats with diabetes.
Topics: Animals; Arterial Pressure; Carnitine; Diabetes Mellitus, Experimental; Erectile Dysfunction; Follic | 2021 |
Comprehensive Analysis of Acylcarnitine Species in db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes.
Topics: Animals; Carnitine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Limit of | 2017 |
Effect of L-carnitine on diabetes-induced changes of skeletal muscles in rats.
Topics: Animals; Antioxidants; Carnitine; Catalase; Diabetes Mellitus, Experimental; Glucose; Glutathione; G | 2018 |
L-carnitine ameliorates peripheral neuropathy in diabetic mice with a corresponding increase in insulin‑like growth factor‑1 level.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Insulin-L | 2019 |
Metabolite aberrations in early diabetes detected in rat kidney using mass spectrometry imaging.
Topics: Amino Acids, Branched-Chain; Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetic Nephropat | 2019 |
Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Carnitine; Cholecalciferol; Diabetes Mellitus, Experim | 2013 |
Effect of systemic carnitine therapy on serum fibronectin level in diabetic rats.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Fibronectins; Graft Survival; Ma | 2014 |
Effects of warfarin and L-carnitine on hemostatic function and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Male; Oxidative Stress; Rats; Rats, Sprague-Daw | 2014 |
Combination therapy with losartan and L-carnitine protects against endothelial dysfunction of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Carnitine; Diabetes Mellitus, Experimental; Drug Therapy, Combination | 2014 |
An LC-MS/MS method to quantify acylcarnitine species including isomeric and odd-numbered forms in plasma and tissues.
Topics: Amino Acids; Animals; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Experimental; Fatty Acid | 2015 |
Validated method for the quantification of free and total carnitine, butyrobetaine, and acylcarnitines in biological samples.
Topics: Animals; Betaine; Carnitine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; | 2015 |
Metabolic Dysfunction Is Restricted to the Sciatic Nerve in Experimental Diabetic Neuropathy.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; | 2016 |
MK2 Deletion in Mice Prevents Diabetes-Induced Perturbations in Lipid Metabolism and Cardiac Dysfunction.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fatty Acids, Noneste | 2016 |
Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diet, High-Fa | 2016 |
Melatonin and L-carnitin improves endothelial disfunction and oxidative stress in Type 2 diabetic rats.
Topics: Animals; Antioxidants; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, | 2016 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Bloo | 2008 |
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Cardiovascular Agents; Carnitin | 2009 |
Impact of experimental diabetes and insulin replacement on epididymal secretory products and sperm maturation in albino rats.
Topics: Androgen-Binding Protein; Animals; Carnitine; Diabetes Mellitus, Experimental; Epididymis; Fertility | 2009 |
Comparison of vitamin E, L-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress.
Topics: Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride Poisoning; Carnitine; Chemical and Drug I | 2009 |
Ameliorating effects of L-carnitine on diabetic podocyte injury.
Topics: Animals; Carnitine; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Express | 2010 |
[Effects of L-carnitine on the apoptosis of spermatogenic cells and epididymal sperm count and motility in rats with diabetes mellitus].
Topics: Animals; Apoptosis; Carnitine; Diabetes Mellitus, Experimental; Epididymis; Male; Rats; Rats, Spragu | 2011 |
Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate.
Topics: Animals; Bile Acids and Salts; Blood Glucose; Carbon Isotopes; Carnitine; Diabetes Mellitus, Experim | 2011 |
[Protective effect of L-carnitine combined with sildenafil on the reproductive endocrine function of diabetic male rats].
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Follicle Stimulating | 2012 |
Serum levo-carnitine levels and skeletal muscle functions in type 2 diabetes mellitus in rodents.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Elec | 2013 |
Discovery of a long-chain carbamoyl aminocarnitine derivative, a reversible carnitine palmitoyltransferase inhibitor with antiketotic and antidiabetic activity.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Butyrates; Carnitine; Carnitine O-Palmitoyltransferas | 2003 |
Effects of L-carnitine treatment on oxidant/antioxidant state and vascular reactivity of streptozotocin-diabetic rat aorta.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Blood Glucose; Carnitine; Catalase; Diabetes Mellitus, | 2003 |
Effects of propionyl-carnitine on mitochondrial respiration and post-ischaemic cardiac function in the ischaemic underperfused diabetic rat heart.
Topics: Animals; Blood Pressure; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental | 2004 |
Short term effects of L-carnitine on serum lipids in STZ-induced diabetic rats.
Topics: Animals; Carnitine; Cholesterol; Diabetes Mellitus, Experimental; Male; Rats; Rats, Wistar; Time Fac | 2004 |
Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics.
Topics: Animals; Base Sequence; Cardiomyopathies; Carnitine; Cricetinae; Diabetes Mellitus, Experimental; DN | 2005 |
Effect of L-carnitine on diabetogenic action of streptozotocin in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Blood Glucose; Carnitine; Diabetes Mellitus, Exp | 2005 |
Cardio-protective effects of carnitine in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Disea | 2006 |
[Effect of L-carnitine to suppress the development of ischemic reperfusion injury in an excised heart of a diabetic rat].
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Myocardial Reperfusi | 2006 |
Carnitine revisited: potential use as adjunctive treatment in diabetes.
Topics: Animals; Calorimetry; Carnitine; Diabetes Mellitus, Experimental; Fatty Acids; Glucose Tolerance Tes | 2007 |
Diabetes-induced bradycardia is an intrinsic metabolic defect reversed by carnitine.
Topics: Animals; Blood Glucose; Body Weight; Bradycardia; Carnitine; Diabetes Mellitus, Experimental; Electr | 2007 |
Metabolic profile changes in the testes of mice with streptozotocin-induced type 1 diabetes mellitus.
Topics: Animals; Betaine; Carnitine; Choline; Creatine; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2009 |
ATP production and TCA activity are stimulated by propionyl-L-carnitine in the diabetic rat heart.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Carnitine; Citric Acid Cycle; Diabetes Mellitus, Exp | 2008 |
Cardiac sarcoplasmic reticulum function in insulin- or carnitine-treated diabetic rats.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Female; Glycated Hemoglobin; Hea | 1983 |
Carnitine content of skeletal muscle from diabetic and insulin-treated diabetic rats.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Insulin; Male; Muscles; Rats; Streptozocin | 1980 |
Ca2+-transport in skeletal muscle sarcoplasmic reticulum of the chronically diabetic rat.
Topics: Animals; Biological Transport; Calcium; Carnitine; Diabetes Mellitus, Experimental; Microsomes; Musc | 1984 |
Carnitine and creatine content of tissues of normal and alloxan-diabetic sheep and rats.
Topics: Animals; Carnitine; Creatine; Diabetes Mellitus, Experimental; Female; Guanidinoacetate N-Methyltran | 1983 |
Salient effects of L-carnitine on adenine-nucleotide loss and coenzyme A acylation in the diabetic heart perfused with excess palmitic acid. A phosphorus-31 NMR and chemical extract study.
Topics: Acyl Coenzyme A; Adenine Nucleotides; Adenosine Triphosphate; Animals; Carnitine; Diabetes Mellitus, | 1984 |
Lipid-mediated impairment of normal energy metabolism in the isolated perfused diabetic rat heart studied by phosphorus-31 NMR and chemical extraction.
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Carnitine; Coenzyme A; Diabetes Mellitus, Experime | 1984 |
Improvement of myocardial function in diabetic rats after treatment with L-carnitine.
Topics: Animals; Blood Glucose; Carnitine; Coenzyme A; Coronary Disease; Diabetes Mellitus, Experimental; Fa | 1984 |
Control of myocardial levels of CoA and carnitine.
Topics: Animals; Biological Transport; Carnitine; Coenzyme A; Cysteine; Cytosol; Diabetes Mellitus, Experime | 1982 |
Metabolic control of prevention of nephropathy by 2-tetradecylglycidate in the diabetic mouse (db/db).
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epoxy Co | 1982 |
Carnitine content of skeletal and cardiac muscle from genetically diabetic (db/db) and control mice.
Topics: Animals; Carnitine; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Fatty Acids; Mic | 1983 |
The effect of alloxan- and streptozotocin-induced diabetes on calcium transport in rat cardiac sarcoplasmic reticulum. The possible involvement of long chain acylcarnitines.
Topics: Animals; Biological Transport; Calcium; Carnitine; Diabetes Mellitus, Experimental; Female; Myocardi | 1983 |
Effect of oral carnitine treatment on cardiac sarcoplasmic reticulum function in streptozotocin induced diabetic rats.
Topics: Animals; Blood Glucose; Calcium; Carnitine; Diabetes Mellitus, Experimental; Female; Heart; Myocardi | 1983 |
A mechanism for reduced myocardial carnitine levels in diabetic animals.
Topics: Animals; Biological Transport; Biomechanical Phenomena; Carnitine; Diabetes Mellitus, Experimental; | 1982 |
Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes.
Topics: Acetylcarnitine; Action Potentials; Animals; Blood Flow Velocity; Blood Glucose; Body Weight; Carnit | 1995 |
L-carnitine increases glucose metabolism and mechanical function following ischaemia in diabetic rat heart.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Glucose; Glycolysis; Heart; In Vitro Techniques | 1995 |
Cardiac glucose and fatty acid oxidation in the streptozotocin-induced diabetic spontaneously hypertensive rat.
Topics: Animals; Carnitine; Coenzyme A; Diabetes Mellitus, Experimental; Energy Metabolism; Fatty Acids; Glu | 1995 |
Neural dysfunction and metabolic imbalances in diabetic rats. Prevention by acetyl-L-carnitine.
Topics: Acetylcarnitine; Animals; Ca(2+) Mg(2+)-ATPase; Carnitine; Diabetes Mellitus, Experimental; Diabetic | 1994 |
Cardiovascular and metabolic changes in spontaneously hypertensive rats following streptozotocin administration.
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Blood Glucose; Blood Pressure; Carnitine; Diabetes Mellitu | 1994 |
Changes in the subcellular distribution of free carnitine and its acyl derivatives in diabetic rat hearts following treatment with L-carnitine.
Topics: Animals; Carnitine; Cytosol; Diabetes Mellitus, Experimental; Male; Mitochondria, Heart; Myocardium; | 1993 |
Effect of acetyl-L-carnitine treatment on the levels of levocarnitine and its derivatives in streptozotocin-diabetic rats.
Topics: Acetylcarnitine; Animals; Behavior, Animal; Blood Glucose; Carnitine; Diabetes Mellitus, Experimenta | 1993 |
Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin-induced diabetes: comparison with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Cardiotonic Agents | 1996 |
Effects of propionyl-L-carnitine and insulin on the electroretinogram, nerve conduction and nerve blood flow in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; | 1996 |
Effect of propionyl-L-carnitine treatment on membrane phospholipid fatty acid turnover in diabetic rat erythrocytes.
Topics: Administration, Oral; Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Eryth | 1995 |
L-propionylcarnitine enhancement of substrate oxidation and mitochondrial respiration in the diabetic rat heart.
Topics: Analysis of Variance; Animals; Biomechanical Phenomena; Cardiotonic Agents; Carnitine; Citric Acid C | 1996 |
Improvement of myocardial function and metabolism in diabetic rats by the carnitine palmitoyl transferase inhibitor Etomoxir.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Experimental; Enzyme Inhibi | 1995 |
Effect of propionyl-L-carnitine on oscillatory potentials in electroretinogram in streptozotocin-diabetic rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; | 1996 |
Comparison of the effects of aminoguanidine and L-carnitine treatments on somatosensorial evoked potentials in alloxan-diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Diabetic N | 1996 |
Metabolic basis of decreased transient outward K+ current in ventricular myocytes from diabetic rats.
Topics: Animals; Carnitine; Cells, Cultured; Diabetes Mellitus, Experimental; Dichloroacetic Acid; Electric | 1996 |
Neurovascular effects of L-carnitine treatment in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Enzyme Inhibitors; | 1997 |
L-carnitine treatment improves brain stem auditory evoked potentials in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Diabetic Neuropathi | 1996 |
In experimental diabetes the decrease in the eye of lens carnitine levels is an early important and selective event.
Topics: Alloxan; Animals; Carnitine; Diabetes Mellitus, Experimental; Eye; Lens, Crystalline; Male; Rabbits; | 1997 |
Metabolic and vascular factors in the pathogenesis of diabetic neuropathy.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endothelium, Vascular; F | 1997 |
Reduced effects of L-carnitine on glucose and fatty acid metabolism in myocytes isolated from diabetic rats.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Carbon Radioisotopes; Carnitine; Citric Acid Cycle; Dia | 1997 |
Effects of propionyl-L-carnitine on cardiac dysfunction in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Expe | 1998 |
Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats.
Topics: Acetylcarnitine; Aldehyde Reductase; Animals; Body Weight; Carnitine; Diabetes Mellitus, Experimenta | 1998 |
Carnitine supplementation improves myocardial function in hearts from ischemic diabetic and euglycemic rats.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Heart; Hemodynamics; In Vitro Te | 1998 |
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; | 1999 |
Propionyl-L-carnitine effects on postischemic recovery of heart function and substrate oxidation in the diabetic rat.
Topics: Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Glucose; Heart; Male; Myoca | 2000 |
Involvement of 1,2-diacylglycerol in improvement of heart function by etomoxir in diabetic rats.
Topics: Animals; Blood Pressure; Carnitine; Ceramides; Diabetes Mellitus, Experimental; Diglycerides; Echoca | 2001 |
Effects of propionyl-L-carnitine on isolated mitochondrial function in the reperfused diabetic rat heart.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; | 2001 |
L-Carnitine changes the levels of insulin-like growth factors (IGFs) and IGF binding proteins in streptozotocin-induced diabetic rat.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relations | 2001 |
Myocardial and hepatic free carnitine concentrations in pups of diabetic female rats.
Topics: Animals; Animals, Newborn; Cardiomyopathies; Carnitine; Diabetes Mellitus, Experimental; Dietary Sup | 2002 |
Enzymic hydrolysis of acetylcarnitine in liver from rats, sheep and cows.
Topics: Animals; Carnitine; Carnitine O-Acetyltransferase; Cattle; Diabetes Mellitus, Experimental; Esters; | 1975 |
[14C]palmitate uptake in isolated rat liver mitochondria: effects of fasting, diabetes mellitus, and inhibitors of carnitine acyltransferase.
Topics: Acyltransferases; Adenosine Triphosphate; Animals; Caprylates; Carnitine; Carnitine Acyltransferases | 1978 |
Carnitine and experimental ketotic and non-ketotic diabetic stupor.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Diabetic Coma; Diabetic Ketoacid | 1979 |
Effect of streptozotocin on carnitine and carnitine acyltransferases in rat heart, liver, and kidney.
Topics: Acyltransferases; Animals; Carnitine; Carnitine Acyltransferases; Diabetes Mellitus, Experimental; K | 1979 |
Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and red
Topics: Acetates; Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Caprylates; Carnitine; Cell Membrane; | 1976 |
Enhancement of mitochondrial carnitine and carnitine acylcarnitine translocase-mediated transport of fatty acids into liver mitochondria under ketogenic conditions.
Topics: Acyltransferases; Animals; Animals, Newborn; Biological Transport, Active; Carnitine; Carnitine Acyl | 1979 |
The heart in diabetes mellitus.
Topics: Animals; Carnitine; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, | 1979 |
Effect of carnitine on branched-chain amino acid oxidation by liver and skeletal muscle.
Topics: Amino Acids; Animals; Caproates; Carnitine; Carnitine Acyltransferases; Diabetes Mellitus, Experimen | 1978 |
Fatty acid and lactate metabolism by heart homogenates from alloxan-diabetic dogs.
Topics: Adenosine Triphosphate; Alloxan; Animals; Carnitine; Diabetes Mellitus, Experimental; Dogs; Fatty Ac | 1978 |
Effects of ischemia on rat myocardial function and metabolism in diabetes.
Topics: Acyl Coenzyme A; Animals; Carnitine; Coenzyme A; Coronary Disease; Diabetes Mellitus, Experimental; | 1979 |
Role of carnitine in hepatic ketogenesis.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Glucagon; Insulin; Ketones; Liver; Male; Oleic | 1975 |
Effect of emeriamine on exocrine and endocrine pancreatic function in normal and diabetic rats.
Topics: Amylases; Animals; Betaine; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Female; Hypog | 1992 |
Effect of propionyl-L-carnitine on experimental induced cardiomyopathy in rats.
Topics: Animals; Blood Pressure; Cardiomyopathies; Carnitine; Diabetes Mellitus, Experimental; Erucic Acids; | 1992 |
Effect of cyclosporine treatment on carnitine and myo-inositol in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Carnitine; Cyclosporine; Diabetes Mellitus, Experimental; Eatin | 1992 |
[The effect of carnitine on the early phase of liver regeneration after partial hepatectomy in rats with experimental diabetes].
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; DNA; Hepatectomy; Liver; Liver Regeneration; Ma | 1992 |
Protection of the ischemic diabetic heart by L-propionylcarnitine therapy.
Topics: Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Male; Myocardial Contractio | 1992 |
Effect of short- and long-term diabetes on carnitine and myo-inositol in rats.
Topics: Acute Disease; Animals; Blood Glucose; Body Weight; Carnitine; Chronic Disease; Diabetes Mellitus, E | 1991 |
Vitamin and micronutrient concentrations in cyclosporine-induced renal tumor from diabetic rats.
Topics: Adenocarcinoma; Animals; Biopterins; Blood Glucose; Carnitine; Cyclosporine; Diabetes Mellitus, Expe | 1991 |
Lack of effect of oral L-carnitine treatment on lipid metabolism and cardiac function in chronically diabetic rats.
Topics: Animals; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Heart; Heart Function Tests; Lipid | 1990 |
Beneficial effect of exercise training on cardiac long-chain acylcarnitine levels in diabetic rats.
Topics: Acylation; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Fatty Acids; Insulin; | 1990 |
Beneficial effect of exercise training on cardiac long-chain acylcarnitine levels in diabetic rats.
Topics: Acylation; Animals; Carnitine; Diabetes Mellitus, Experimental; Male; Myocardium; Physical Condition | 1990 |
Na(+)-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats.
Topics: Amiloride; Animals; Calcium; Carnitine; Carrier Proteins; Diabetes Mellitus, Experimental; Hydrogen; | 1990 |
Effect of genetic diabetes and alcohol on tissue carnitine and inositol concentrations in mice.
Topics: Alcohol Drinking; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Inositol; Male | 1990 |
Influence of carnitine acyltransferase inhibitors on the performance and metabolism of rat cardiac muscle.
Topics: Acyltransferases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Chemical Phenomena; Chemistr | 1990 |
Effects of in vivo and in vitro treatment with L-carnitine on isolated hearts from chronically diabetic rats.
Topics: Adipose Tissue; Animals; Blood Pressure; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Dr | 1990 |
Effect of L-carnitine treatment on lipid metabolism and cardiac performance in chronically diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Carnitine; Cholesterol; Chronic Disease; Diabetes Mellitus, Exp | 1988 |
Regulation of gluconeogenesis in hepatocytes from fasted alloxan-diabetic rats.
Topics: Animals; Bucladesine; Carnitine; Diabetes Mellitus, Experimental; Dihydroxyacetone; Fasting; Glucone | 1985 |
Age-related change in ketone body metabolism: diminished glucagon effect on ketogenesis in adult rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Carnitine; Cyclic AMP; Diabetes Mellitus, Expe | 1987 |
Myocardial adaptation to endurance exercise training in diabetic rats.
Topics: Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Cardiac Output; Carnitine; Cholester | 1987 |
Prevention of the effects of diabetes on rat cardiac performance and lipid metabolism by L-carnitine.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Heart; Lipid Metabolism; Male; Myocardium; Rats | 1988 |
Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines.
Topics: Acyltransferases; Animals; Betaine; Blood Glucose; Caprylates; Carnitine; Carnitine O-Palmitoyltrans | 1986 |
Acute diabetes mellitus does not impair survival rate in rats submitted to left coronary artery ligation.
Topics: Acute Disease; Animals; Blood Glucose; Carnitine; Coronary Disease; Coronary Vessels; Creatine Kinas | 1987 |
In vivo and in vitro intervention with L-carnitine prevents abnormal energy metabolism in isolated diabetic rat heart: chemical and phosphorus-31 NMR evidence.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Energy Metabolism; Heart; Ketone | 1987 |
Ester composition of carnitine in the perfusate of liver and in the plasma of donor rats.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Eating; Esters; Fasting; Liver; Male; Perfusion | 1987 |
Reduction of ischemia-induced acyl carnitine accumulation by TDGA and its influence on lactate dehydrogenase release in diabetic rat hearts.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Coronary Disease; Diabetes Mellitus, Ex | 1986 |
Effects of triiodothyronine and carnitine therapy on myocardial dysfunction in diabetic rats.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Female; Heart Diseases; Myocardial Contraction; | 1986 |
Carnitine in the streptozotocin-diabetic rat.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Diet; Insulin; Kidney; Liver; Ma | 1985 |
Inhibition of palmitoylcarnitine oxidation by pyruvate in rat heart mitochondria.
Topics: Animals; Biological Transport; Carnitine; Coumaric Acids; Diabetes Mellitus, Experimental; Dichloroa | 1985 |
Inhibitory effects of some long-chain unsaturated fatty acids on mitochondrial beta-oxidation. Effects of streptozotocin-induced diabetes on mitochondrial beta-oxidation of polyunsaturated fatty acids.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Male; Mitochondria, L | 1985 |
Activation of palmityl-coA: carnitine palmityltransferase in livers from fasted, fat-fed, or diabetic rats.
Topics: Animals; Carnitine; Dactinomycin; Diabetes Mellitus, Experimental; Dietary Fats; Ethionine; Fasting; | 1965 |
Studies with (plus)--octanoylcarnitine in experimental diabetic ketoacidosis.
Topics: Administration, Oral; Animals; Blood Glucose; Caproates; Caprylates; Carnitine; Depression, Chemical | 1974 |
Carnitine palmitoyltransferase activities (1 and 2) and the rate of palmitate oxidation in liver mitochondria from diabetic rats.
Topics: Acyltransferases; Adenosine Triphosphatases; Animals; Blood Glucose; Carbon Isotopes; Carnitine; Coe | 1972 |
-Oxoglutarate carboxylation in liver mitochondria from normal, alloxan diabetic and streptozotocin diabetic rats.
Topics: Animals; Caprylates; Carbon Dioxide; Carnitine; Citrates; Citric Acid Cycle; Cyclic AMP; Depression, | 1972 |
Reversible inhibition of adenine nucleotide translocation by long chain fatty acyl coenzyme A esters in liver mitochondria of diabetic and hibernating animals.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Isotopes; Carnitine; Coenzyme A; Diab | 1972 |
The liver as the site of carnitine biosynthesis in sheep with alloxan-induced diabetes.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Hepatic Veins; Kidney Cortex; Liver; Male; Musc | 1974 |
On the mechanism of ketogenesis and its control. I. On a possible role of acetoacetyl-CoA thiolase in the control of ketone body production.
Topics: Acetates; Acetoacetates; Acetyltransferases; Acute Disease; Animals; Aspartic Acid; Carbon Radioisot | 1973 |
Relationships between carnitine and coenzyme A esters in tissues of normal and alloxan-diabetic sheep.
Topics: Acyltransferases; Animals; Carnitine; Coenzyme A; Cytoplasm; Diabetes Mellitus, Experimental; Esters | 1972 |
Aspects of carnitine ester metabolism in sheep liver.
Topics: Acetates; Acyltransferases; Animal Feed; Animals; Carnitine; Cattle; Coenzyme A; Diabetes Mellitus, | 1970 |
Turnover rates and intracellular pool size distribution of citrate cycle intermediates in normal, diabetic and fat-fed rats estimated by computer analysis from specific activity decay data of 14C-labeled citrate cycle acids.
Topics: Acetates; Acetoacetates; Acidosis; Animals; Aspartic Acid; Carbon Isotopes; Carnitine; Chromatograph | 1970 |
Carnitine-14C metabolism in choline-deficient, alloxan-diabetic choline-deficient and insulin-treated rats.
Topics: Animals; Carbon Isotopes; Carnitine; Choline Deficiency; Chromatography, Paper; Diabetes Mellitus, E | 1971 |
The role of ATP citrate lyase in the transfer of acetyl groups in rat liver.
Topics: Aniline Compounds; Animals; Carbon Isotopes; Carnitine; Citrates; Coenzyme A; Colorimetry; Diabetes | 1968 |
Metabolism, turnover time, half life, body pool of carnitine-14C in normal, alloxan diabetic and insulin treated rats.
Topics: Animals; Carbon Isotopes; Carnitine; Diabetes Mellitus, Experimental; Insulin; Male; Muscles; Rats | 1969 |
Rates of ketone-body formation in the perfused rat liver.
Topics: Acetoacetates; Animals; Carnitine; Diabetes Mellitus, Experimental; Diet; Fatty Acids; Female; Hydro | 1969 |