Page last updated: 2024-10-16

carnitine and Alcohol Abuse

carnitine has been researched along with Alcohol Abuse in 23 studies

Research Excerpts

ExcerptRelevanceReference
"The plasma level of carnitine, a co-factor involved in many metabolic reactions, is high in alcoholic liver cirrhosis, due to an increased amount of esterified carnitine."7.68Plasma carnitine levels in liver cirrhosis: relationship with nutritional status and liver damage. ( Amodio, P; Angeli, P; Gatta, A; Menon, F; Merkel, C, 1990)
" Chronic administration of alcohol induces liver injury, inflammation, cirrhosis, focal necrosis and steatosis."6.47[Carnitine: function, metabolism and value in hepatic failure during chronic alcohol intoxication]. ( Chojnowska, S; Kępka, A; Ladny, JR; Płudowski, P; Rudy, M; Szajda, SD; Szulc, A; Waszkiewicz, N; Zwierz, K, 2011)
"Serum aspartate, alanine aminotransferases (AST, ALT), and plasma carnitine are all indirect biomarkers of alcohol abuse."3.91Relation of plasma carnitine and aminotransferases to alcohol dose and time of dependence. ( Chojnowska, S; Kępka, A; Ochocińska, A; Skorupa, E; Szajda, SD; Szczepański, M; Waszkiewicz, N; Zwierz, P, 2019)
"The results showed: i) no difference between the alcohol/no alcohol groups, with or without carnitine, regarding body weight gain, diet consumption, urinary nitrogen excretion, plasma free fatty acids, lysine, methionine, and glycine."3.76Failure of carnitine in improving hepatic nitrogen content in alcoholic and non-alcoholic malnourished rats. ( Jordão, AA; Marchini, JS; Padovan, GJ; Portari, GV; Rodrigues, LP; Suen, V, 2010)
"The plasma level of carnitine, a co-factor involved in many metabolic reactions, is high in alcoholic liver cirrhosis, due to an increased amount of esterified carnitine."3.68Plasma carnitine levels in liver cirrhosis: relationship with nutritional status and liver damage. ( Amodio, P; Angeli, P; Gatta, A; Menon, F; Merkel, C, 1990)
"Recent studies in alcohol use disorders (AUDs) have demonstrated some connections between carnitine metabolism and the pathophysiology of the disease."2.72Carnitine in Alcohol Use Disorders: A Scoping Review. ( Bota, AB; DiBattista, A; Simmons, JG; Wilson, K, 2021)
" Chronic administration of alcohol induces liver injury, inflammation, cirrhosis, focal necrosis and steatosis."2.47[Carnitine: function, metabolism and value in hepatic failure during chronic alcohol intoxication]. ( Chojnowska, S; Kępka, A; Ladny, JR; Płudowski, P; Rudy, M; Szajda, SD; Szulc, A; Waszkiewicz, N; Zwierz, K, 2011)
" Therapy for increasing sperm motility includes low dosage androgen and human chorionic gonadotropin."2.36Sperm motility. ( Amelar, RD; Dubin, L; Schoenfeld, C, 1980)
"The patients' alcohol dependence ranged from 2 to 30 years (13."1.39Plasma carnitine concentrations after chronic alcohol intoxication. ( Chojnowska, S; Kępka, A; Konarzewska, E; Ladny, JR; Płudowski, P; Szajda, SD; Szulc, A; Waszkiewicz, N; Zalewska-Szajda, B; Zwierz, K, 2013)
" During the chronic use of alcohol the decrease of concentration of L-carnitine is marked."1.33[Change of concentration of L-carnitine in blood and other tissues in rats on a background of the alcohol intake and influence of mildronate on its level]. ( Sakvarelidze, EP, 2006)
"Carnitine plays a central role in lipid metabolism."1.28Increased plasma carnitine in severe alcohol dependence. ( Bartlett, S; Chalmers, R; Glass, IB; Littleton, J, 1989)
"Thus, ketosis is viewed as the result of increased mobilization of free fatty acids from adipose tissue (site 1) to the liver (site 2), coupled with simultaneous enhancement of the liver's capacity to convert these substrates into acetoacetic and beta-hydroxybutyric acids."1.26Hormonal control of ketogenesis. Biochemical considerations. ( Foster, DW; McGarry, JD, 1977)
"Physical dependence on ethanol was induced in TO strain mice by chronic administration of ethanol by inhalation."1.26Hepatic triglyceride accumulation and the ethanol physical withdrawal syndrome in mice. ( Begg, SJ; Griffiths, PJ; Littleton, JM; Murad, CA, 1977)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199012 (52.17)18.7374
1990's4 (17.39)18.2507
2000's1 (4.35)29.6817
2010's4 (17.39)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Bota, AB1
Simmons, JG1
DiBattista, A1
Wilson, K1
Kärkkäinen, O1
Kokla, M1
Lehtonen, M1
Auriola, S1
Martiskainen, M1
Tiihonen, J1
Karhunen, PJ1
Hanhineva, K1
Kok, E1
Kępka, A3
Zwierz, P1
Chojnowska, S3
Ochocińska, A1
Skorupa, E1
Szczepański, M1
Szajda, SD3
Waszkiewicz, N3
Zalewska-Szajda, B1
Płudowski, P2
Konarzewska, E1
Szulc, A2
Ladny, JR2
Zwierz, K2
Rodrigues, LP1
Portari, GV1
Padovan, GJ1
Jordão, AA1
Suen, V1
Marchini, JS1
Rudy, M1
Sakvarelidze, EP1
Leonard, BE2
Corbett, R1
Amelar, RD1
Dubin, L1
Schoenfeld, C1
Conte, A1
Bianchi, I1
Guazzelli, M1
Taponeco, G1
Bertelli, A1
Ronca, G1
McGarry, JD1
Foster, DW1
Williams, ES1
Li, TK1
Murad, CA1
Begg, SJ1
Griffiths, PJ1
Littleton, JM1
Amodio, P1
Angeli, P1
Merkel, C1
Menon, F1
Gatta, A1
Tempesta, E1
Troncon, R1
Janiri, L1
Colusso, L1
Riscica, P1
Saraceni, G1
Gesmundo, E1
Calvani, M1
Benedetti, N1
Pola, P1
Alonso de la Peña, C1
Rozas, I1
Alvarez-Prechous, A1
Pardiñas, MC1
Paz, JM1
Rodriguez-Segade, S1
Glass, IB1
Chalmers, R1
Bartlett, S1
Littleton, J1
Fuller, RK1
Hoppel, CL1
de Sousa, C1
Leung, NW1
Chalmers, RA1
Peters, TJ1
De la Morena, E1
Berlanas, EJ1
Gomez, C1
Rhew, TH1
Sachan, DS1
Rabinovitch, MA1
Kalff, V1
Allen, R1
Rosenthal, A1
Albers, J1
Das, SK1
Pitt, B1
Swanson, DP1
Mangner, T1
Rogers, WL1

Reviews

3 reviews available for carnitine and Alcohol Abuse

ArticleYear
Carnitine in Alcohol Use Disorders: A Scoping Review.
    Alcoholism, clinical and experimental research, 2021, Volume: 45, Issue:4

    Topics: Alcoholism; Carnitine; Dietary Supplements; Humans

2021
[Carnitine: function, metabolism and value in hepatic failure during chronic alcohol intoxication].
    Postepy higieny i medycyny doswiadczalnej (Online), 2011, Oct-07, Volume: 65

    Topics: Alcohol Drinking; Alcoholism; Carnitine; Fatty Acids; Humans; Lipid Metabolism; Liver; Liver Failure

2011
Sperm motility.
    Fertility and sterility, 1980, Volume: 34, Issue:3

    Topics: Alcoholism; Androgens; Caffeine; Carnitine; Chorionic Gonadotropin; Coitus; Cyclic AMP; Ejaculation;

1980

Trials

1 trial available for carnitine and Alcohol Abuse

ArticleYear
Role of acetyl-L-carnitine in the treatment of cognitive deficit in chronic alcoholism.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:1-2

    Topics: Acetylcarnitine; Adult; Alcoholism; Carnitine; Clinical Trials as Topic; Cognition Disorders; Double

1990

Other Studies

19 other studies available for carnitine and Alcohol Abuse

ArticleYear
Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use.
    Addiction biology, 2021, Volume: 26, Issue:6

    Topics: Adult; Aged; Alcoholism; Autopsy; Body Mass Index; Carnitine; Cerebrospinal Fluid; Chromatography, L

2021
Relation of plasma carnitine and aminotransferases to alcohol dose and time of dependence.
    Alcohol (Fayetteville, N.Y.), 2019, Volume: 81

    Topics: Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Biomarkers; Carnitine; Case-Co

2019
Plasma carnitine concentrations after chronic alcohol intoxication.
    Postepy higieny i medycyny doswiadczalnej (Online), 2013, May-31, Volume: 67

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Carnitine; Female; Humans; Male; Middle Aged; Plasma; Ref

2013
Failure of carnitine in improving hepatic nitrogen content in alcoholic and non-alcoholic malnourished rats.
    Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:9

    Topics: Alcoholism; Animals; Carnitine; Dietary Supplements; Ethanol; Fatty Acids, Nonesterified; Fatty Live

2010
[Change of concentration of L-carnitine in blood and other tissues in rats on a background of the alcohol intake and influence of mildronate on its level].
    Georgian medical news, 2006, Issue:137

    Topics: Alcoholism; Animals; Cardiovascular Agents; Carnitine; Ethanol; Male; Methylhydrazines; Rats; Rats,

2006
Possible relationships between thiamine, carnitine, polyunsaturated fatty acids and the neurotoxicity of alcohol.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1984, Volume: 19, Issue:2

    Topics: Alcoholism; Animals; Carnitine; Ethanol; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Humans; Lin

1984
Effects of carnitine on changes caused by chronic administration of alcohol.
    Neuropharmacology, 1984, Volume: 23, Issue:2B

    Topics: Alcoholism; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Carnitine; Exploratory Beha

1984
Effect of L-propionyl carnitine on some properties of erythrocytes and leukocytes of alcohol abusers.
    International journal of tissue reactions, 1995, Volume: 17, Issue:1

    Topics: Alcoholism; Blood Donors; Carnitine; Case-Control Studies; Chemotaxis, Leukocyte; Cytochrome c Group

1995
Hormonal control of ketogenesis. Biochemical considerations.
    Archives of internal medicine, 1977, Volume: 137, Issue:4

    Topics: Acetoacetates; Acidosis; Adipose Tissue; Alcoholism; Animals; Carnitine; Carnitine Acyltransferases;

1977
The effect of chronic alcohol administration on fatty acid metabolism and pyruvate oxidation of heart mitochondria.
    Journal of molecular and cellular cardiology, 1977, Volume: 9, Issue:12

    Topics: Acetylcarnitine; Alcoholism; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Huma

1977
Hepatic triglyceride accumulation and the ethanol physical withdrawal syndrome in mice.
    British journal of experimental pathology, 1977, Volume: 58, Issue:6

    Topics: Alcoholism; Animals; Carbon Tetrachloride; Carnitine; Ethanol; Female; Humans; Liver; Male; Mice; Su

1977
Plasma carnitine levels in liver cirrhosis: relationship with nutritional status and liver damage.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1990, Volume: 28, Issue:9

    Topics: Adult; Aged; Alcoholism; Carnitine; Female; gamma-Glutamyltransferase; Humans; Kidney; Liver; Liver

1990
Free carnitine and acylcarnitine levels in sera of alcoholics.
    Biochemical medicine and metabolic biology, 1990, Volume: 44, Issue:1

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Alcoholism; Carnitine; Female; Humans; Liver Cirrhosis, Al

1990
Increased plasma carnitine in severe alcohol dependence.
    British journal of addiction, 1989, Volume: 84, Issue:6

    Topics: Adult; Alcohol Drinking; Alcoholism; Carnitine; Dose-Response Relationship, Drug; Female; Humans; Ma

1989
Plasma carnitine in alcoholism.
    Alcoholism, clinical and experimental research, 1988, Volume: 12, Issue:5

    Topics: Adult; Alcoholism; Carnitine; Humans; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Middle

1988
Free and total carnitine and acylcarnitine content of plasma, urine, liver and muscle of alcoholics.
    Clinical science (London, England : 1979), 1988, Volume: 75, Issue:4

    Topics: Acylation; Adult; Aged; Alcoholism; Carnitine; Fatty Liver, Alcoholic; Female; Humans; Liver; Male;

1988
Levo-carnitine, its derivatives, and free fatty acids in serum, heart, liver, and muscle of both tumoral and alcoholic rats.
    Clinical therapeutics, 1988, Volume: 10, Issue:6

    Topics: Alcoholism; Animals; Carnitine; Fatty Acids; Fatty Acids, Nonesterified; Liver; Muscles; Myocardium;

1988
Dose-dependent lipotropic effect of carnitine in chronic alcoholic rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:11

    Topics: Alcoholism; Animals; Carnitine; Cholesterol; Dose-Response Relationship, Drug; Lipid Metabolism; Lip

1986
omega-123I-hexadecanoic acid metabolic probe of cardiomyopathy.
    European journal of nuclear medicine, 1985, Volume: 10, Issue:5-6

    Topics: Adolescent; Adult; Aged; Alcoholism; Atrial Fibrillation; Cardiomyopathies; Cardiomyopathy, Dilated;

1985