Page last updated: 2024-10-16

carnitine and Akinetic-Rigid Variant of Huntington Disease

carnitine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 6 studies

Research Excerpts

ExcerptRelevanceReference
"The carnitine shuttle is a complex consisting of three enzymes whose function is to transport the long-chain fatty acids into the mitochondria."1.72The Reversible Carnitine Palmitoyltransferase 1 Inhibitor (Teglicar) Ameliorates the Neurodegenerative Phenotype in a Drosophila Huntington's Disease Model by Acting on the Expression of Carnitine-Related Genes. ( Bertapelle, C; Cacciola, NA; Carillo, MR; Digilio, FA; Peluso, G; Shidlovskii, YV, 2022)
"L-carnitine plays a role in facilitating the mitochondrial transport of fatty acids, but it also protects the cells from oxidative damage."1.36Neuroprotective effects of L-carnitine in a transgenic animal model of Huntington's disease. ( Klivenyi, P; Vamos, E; Vecsei, L; Voros, K, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Bertapelle, C1
Carillo, MR1
Cacciola, NA1
Shidlovskii, YV1
Peluso, G2
Digilio, FA2
Castilhos, RM1
Augustin, MC1
Santos, JAD1
Pedroso, JL1
Barsottini, O1
Saba, R1
Ferraz, HB1
Vargas, FR1
Furtado, GV1
Polese-Bonatto, M1
Rodrigues, LP1
Sena, LS1
Vargas, CR1
Saraiva-Pereira, ML1
Jardim, LB1
Neurogenética, R1
Di Cristo, F1
Calarco, A1
Sinicropi, MS1
Rosano, C1
Galderisi, U1
Melone, MAB1
Saturnino, C1
Vamos, E1
Voros, K1
Vecsei, L1
Klivenyi, P1
Cuturic, M1
Abramson, RK1
Moran, RR1
Hardin, JW1
Frank, EM1
Sellers, AA1
Goety, CG1
Tanner, CM1
Cohen, JA1
Thelen, JA1
Carroll, VS1
Klawans, HL1
Fariello, RG1

Trials

1 trial available for carnitine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
L-acetyl-carnitine in Huntington's disease: double-blind placebo controlled crossover study of drug effects on movement disorder and dementia.
    Movement disorders : official journal of the Movement Disorder Society, 1990, Volume: 5, Issue:3

    Topics: Acetylcarnitine; Adult; Aged; Carnitine; Dementia; Double-Blind Method; Female; Humans; Huntington D

1990

Other Studies

5 other studies available for carnitine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
The Reversible Carnitine Palmitoyltransferase 1 Inhibitor (Teglicar) Ameliorates the Neurodegenerative Phenotype in a Drosophila Huntington's Disease Model by Acting on the Expression of Carnitine-Related Genes.
    Molecules (Basel, Switzerland), 2022, May-13, Volume: 27, Issue:10

    Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Disease Models, Animal; Drosophila; Huntington

2022
Free carnitine and branched chain amino acids are not good biomarkers in Huntington's disease.
    Arquivos de neuro-psiquiatria, 2020, Volume: 78, Issue:2

    Topics: Amino Acids, Branched-Chain; Biomarkers; Carnitine; Humans; Huntington Disease

2020
The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity.
    International journal of molecular sciences, 2020, Oct-08, Volume: 21, Issue:19

    Topics: Animals; Carnitine; Cell Line; Cell Survival; Disease Models, Animal; Drosophila melanogaster; Drug

2020
Neuroprotective effects of L-carnitine in a transgenic animal model of Huntington's disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:4

    Topics: Animals; Behavior, Animal; Carnitine; Disease Models, Animal; Huntington Disease; Injections, Intrap

2010
Serum carnitine levels and levocarnitine supplementation in institutionalized Huntington's disease patients.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34, Issue:1

    Topics: Adult; Anticonvulsants; Carnitine; Databases, Factual; Diet; Dietary Supplements; Female; Hospitaliz

2013