Page last updated: 2024-10-16

carnitine and Acute Kidney Failure

carnitine has been researched along with Acute Kidney Failure in 27 studies

Research Excerpts

ExcerptRelevanceReference
"This controlled pilot cohort study of 48 children investigated effects of levocarnitine supplementation on myocardial strain in children receiving CKRT for acute kidney injury (AKI)."8.02Effect of levocarnitine supplementation on myocardial strain in children with acute kidney injury receiving continuous kidney replacement therapy: a pilot study. ( Clauss, S; Moudgil, A; Sgambat, K, 2021)
"Cimetidine treatment significantly decreased creatinine, BUN, K, Na, SBP and creatine kinase and increased GFR and urine volume compared to group II."5.42A study on the effect of cimetidine and L-carnitine on myoglobinuric acute kidney injury in male rats. ( Eissa, H; Elattar, S; Estaphan, S; Farouk, M; Rashed, L, 2015)
"Treatment of L-carnitine 30 min prior to reperfusion significantly relieved I/R-induced metabolomic changes."5.38Metabolomic changes and protective effect of (L)-carnitine in rat kidney ischemia/reperfusion injury. ( Dai, W; Hu, W; Ji, C; Liu, Y; Mei, C; Yan, S; Zhang, W, 2012)
"This controlled pilot cohort study of 48 children investigated effects of levocarnitine supplementation on myocardial strain in children receiving CKRT for acute kidney injury (AKI)."4.02Effect of levocarnitine supplementation on myocardial strain in children with acute kidney injury receiving continuous kidney replacement therapy: a pilot study. ( Clauss, S; Moudgil, A; Sgambat, K, 2021)
"It has been found that L-carnitine ameliorated cisplatin-induced acute kidney injury (AKI) in rats."3.85L-Carnitine Ameliorates the Decrease of Aquaporin 2 Levels in Rats with Cisplatin-Induced Kidney Injury. ( Gao, J; Gao, Y; Gu, Z; Li, M; Liang, B; Na, Y; Wei, J; Xu, Y, 2017)
"We have previously shown that carboplatin induces inflammation and apoptosis in renal tubular cells (RTCs) through the activation of the nuclear factor of activated T cells-3 (NFAT3) protein by reactive oxygen species (ROS), and that the ROS-mediated activation of NFAT3 is prevented by N-acetyl cysteine and heme oxygenase-1 treatment."3.80L-carnitine protects against carboplatin-mediated renal injury: AMPK- and PPARα-dependent inactivation of NFAT3. ( Chang, CC; Chou, HC; Chou, Y; Juan, SH; Sue, YM; Yang, NJ, 2014)
"Phenazopyridine (Pyridium) is a commonly used urinary tract analgesic."2.43Acute renal failure due to phenazopyridine (Pyridium) overdose: case report and review of the literature. ( Abitbol, C; Berho, ME; Chandar, J; Espinoza, V; Onder, AM; Zilleruelo, G, 2006)
"L-carnitine or furosemide was administered, and serial blood samples were collected and analyzed to assess the effects of hydronephrosis on the pharmacokinetic parameters."1.56Rats with congenital hydronephrosis show increased susceptibility to renal ischemia-reperfusion injury. ( Cirule, H; Dambrova, M; Liepinsh, E; Sevostjanovs, E; Videja, M; Vilks, K; Vilskersts, R; Zharkova-Malkova, O, 2020)
"Cimetidine treatment significantly decreased creatinine, BUN, K, Na, SBP and creatine kinase and increased GFR and urine volume compared to group II."1.42A study on the effect of cimetidine and L-carnitine on myoglobinuric acute kidney injury in male rats. ( Eissa, H; Elattar, S; Estaphan, S; Farouk, M; Rashed, L, 2015)
"Treatment of L-carnitine 30 min prior to reperfusion significantly relieved I/R-induced metabolomic changes."1.38Metabolomic changes and protective effect of (L)-carnitine in rat kidney ischemia/reperfusion injury. ( Dai, W; Hu, W; Ji, C; Liu, Y; Mei, C; Yan, S; Zhang, W, 2012)
"Hypoparathyroidism has been previously reported in some MFAO deficiencies but has never been mentioned in association with MCADD."1.35Hypoketotic hypoglycemia with myolysis and hypoparathyroidism: an unusual association in medium chain acyl-CoA desydrogenase deficiency (MCADD). ( Baruteau, J; Bloom, MC; Broué, P; Levade, T; Mesli, S; Redonnet-Vernhet, I, 2009)
" The recommended dosage of clofibrate is 1."1.26[Fat and renal failure--therapeutic aspects]. ( Heidland, A; Hörl, M; Hörl, WH, 1982)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19906 (22.22)18.7374
1990's0 (0.00)18.2507
2000's5 (18.52)29.6817
2010's13 (48.15)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Sabry, MM1
Ahmed, MM1
Maksoud, OMA1
Rashed, L2
Morcos, MA1
El-Maaty, AA1
Maher Galal, A1
Sharawy, N1
Vilskersts, R1
Vilks, K1
Videja, M1
Cirule, H1
Zharkova-Malkova, O1
Sevostjanovs, E1
Dambrova, M1
Liepinsh, E1
Sgambat, K2
Clauss, S1
Moudgil, A2
Dastan, F1
Talasaz, AH1
Mojtahedzadeh, M1
Karimi, A1
Salehiomran, A1
Bina, P1
Jalali, A1
Alabi, QK1
Akomolafe, RO1
Olukiran, OS1
Nafiu, AO1
Adefisayo, MA1
Owotomo, OI1
Omole, JG1
Olamilosoye, KP1
Wan, X1
Li, X1
Wang, Q1
Zheng, B1
Zhou, C1
Kang, X1
Hu, D1
Bao, H1
Peng, A1
Sue, YM1
Chou, HC1
Chang, CC1
Yang, NJ1
Chou, Y1
Juan, SH1
Estaphan, S1
Eissa, H1
Elattar, S1
Farouk, M1
Gao, J1
Gu, Z1
Li, M1
Xu, Y1
Gao, Y1
Wei, J1
Liang, B1
Na, Y1
Ustundag, S1
Sen, S1
Yalcin, O1
Ciftci, S1
Demirkan, B1
Ture, M1
Al-Shabanah, OA1
Aleisa, AM1
Al-Yahya, AA1
Al-Rejaie, SS1
Bakheet, SA1
Fatani, AG1
Sayed-Ahmed, MM1
Baruteau, J1
Levade, T1
Redonnet-Vernhet, I1
Mesli, S1
Bloom, MC1
Broué, P1
Uzunoglu, S1
Karagol, H1
Ozpuyan, F1
Cosar, R1
Cicin, I1
Yurutcaloglu, V1
Denizli, B1
Tanriverdi, Ö1
Sut, N1
Kocak, Z1
Yuksel, S1
Sezer, MT1
Sahin, O1
Sutcu, R1
Koçogullari, C1
Yilmaz, HR1
Uz, E1
Kara, Y1
Aydin, B1
Altuntas, A1
Savranlar, Y1
Sönmez, MF1
Sun, J1
Shannon, M1
Ando, Y1
Schnackenberg, LK1
Khan, NA1
Portilla, D1
Beger, RD1
Liu, Y1
Yan, S1
Ji, C1
Dai, W1
Hu, W1
Zhang, W1
Mei, C1
Enomoto, A1
Endou, H1
Onder, AM1
Espinoza, V1
Berho, ME1
Chandar, J1
Zilleruelo, G1
Abitbol, C1
Sharma, AP1
Greenberg, CR1
Prasad, AN1
Prasad, C1
Druml, W1
Laggner, A1
Lenz, K1
Balcke, P1
Kleinberger, G1
Schmidt, P1
Hörl, WH3
Hörl, M1
Heidland, A1
Bank, WJ1
DiMauro, S1
Bonilla, E1
Capuzzi, DM1
Rowland, LP1
Wanner, C2
Riegel, W1
Schaefer, RM1
Guarnieri, G1
Toigo, G1
Crapesi, L1
Situlin, R1
Del Bianco, MA1
Corsi, M1
LoGreco, P1
Paviotti, G1
Mioni, G1
Campanacci, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study: Effect of Carnitine Supplementation on Acylcarnitine Profile and Myocardial Function in Children and Young Adults Receiving Continuous Renal Replacement Therapy[NCT01941823]29 participants (Actual)Observational2014-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for carnitine and Acute Kidney Failure

ArticleYear
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease.
    Clinical and experimental nephrology, 2005, Volume: 9, Issue:3

    Topics: Acute Kidney Injury; Animals; Carnitine; Carrier Proteins; Free Radical Scavengers; Humans; Kidney F

2005
Acute renal failure due to phenazopyridine (Pyridium) overdose: case report and review of the literature.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:11

    Topics: Acetylcysteine; Acute Kidney Injury; Adolescent; Carnitine; Female; HIV Infections; Humans; Infectio

2006
Carnitine abnormalities in patients with renal insufficiency. Pathophysiological and therapeutical aspects.
    Nephron, 1988, Volume: 50, Issue:2

    Topics: Acute Kidney Injury; Carnitine; Humans; Kidney Diseases; Kidney Failure, Chronic; Renal Dialysis

1988
Carnitine metabolism in chronic renal failure.
    Kidney international. Supplement, 1987, Volume: 22

    Topics: Acetates; Acute Kidney Injury; Carnitine; Humans; Renal Dialysis; Uremia

1987

Trials

1 trial available for carnitine and Acute Kidney Failure

ArticleYear
Randomized Trial of Carnitine for the Prevention of Perioperative Atrial Fibrillation.
    Seminars in thoracic and cardiovascular surgery, 2018,Spring, Volume: 30, Issue:1

    Topics: Acute Kidney Injury; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; C-Reactive Prote

2018

Other Studies

22 other studies available for carnitine and Acute Kidney Failure

ArticleYear
Carnitine, apelin and resveratrol regulate mitochondrial quality control (QC) related proteins and ameliorate acute kidney injury: role of hydrogen peroxide.
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:5

    Topics: Acute Kidney Injury; Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensins; Animals; Antio

2022
Rats with congenital hydronephrosis show increased susceptibility to renal ischemia-reperfusion injury.
    Physiological reports, 2020, Volume: 8, Issue:22

    Topics: Acute Kidney Injury; Animals; Carnitine; Cell Adhesion Molecules; Disease Susceptibility; Diuretics;

2020
Effect of levocarnitine supplementation on myocardial strain in children with acute kidney injury receiving continuous kidney replacement therapy: a pilot study.
    Pediatric nephrology (Berlin, Germany), 2021, Volume: 36, Issue:6

    Topics: Acute Kidney Injury; Carnitine; Child; Continuous Renal Replacement Therapy; Dietary Supplements; Hu

2021
Combined Administration of l-Carnitine and Ascorbic Acid Ameliorates Cisplatin-Induced Nephrotoxicity in Rats.
    Journal of the American College of Nutrition, 2018, Volume: 37, Issue:5

    Topics: Acute Kidney Injury; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Body Weight; Carnitine; Cispl

2018
Metabolitic profiling of amino acids in paraquat-induced acute kidney injury.
    Clinical and experimental nephrology, 2019, Volume: 23, Issue:4

    Topics: Acute Kidney Injury; Adult; Amino Acids; Area Under Curve; Biomarkers; Carnitine; Case-Control Studi

2019
L-carnitine protects against carboplatin-mediated renal injury: AMPK- and PPARα-dependent inactivation of NFAT3.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Apoptosis; Carboplatin; Carnitine; Cycl

2014
A study on the effect of cimetidine and L-carnitine on myoglobinuric acute kidney injury in male rats.
    Injury, 2015, Volume: 46, Issue:7

    Topics: Acute Kidney Injury; Animals; Carnitine; Cimetidine; Creatine Kinase; Creatinine; Disease Models, An

2015
Carnitine deficiency in children receiving continuous renal replacement therapy.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2016, Volume: 20, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Cardiomyopathies; Carnitine; Child; Child, Preschool; Female

2016
L-Carnitine Ameliorates the Decrease of Aquaporin 2 Levels in Rats with Cisplatin-Induced Kidney Injury.
    Nephron, 2017, Volume: 135, Issue:4

    Topics: Acute Kidney Injury; Adenylyl Cyclases; Animals; Aquaporin 2; Arginine Vasopressin; Carnitine; Cispl

2017
L-Carnitine ameliorates glycerol-induced myoglobinuric acute renal failure in rats.
    Renal failure, 2009, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Animals; Carnitine; Glycerol; Kidney; Male; Malondialdehyde; Myoglobinuria; Oxi

2009
Increased urinary losses of carnitine and decreased intramitochondrial coenzyme A in gentamicin-induced acute renal failure in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:1

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Carnitine; Coenzyme A; Cr

2010
Hypoketotic hypoglycemia with myolysis and hypoparathyroidism: an unusual association in medium chain acyl-CoA desydrogenase deficiency (MCADD).
    Journal of pediatric endocrinology & metabolism : JPEM, 2009, Volume: 22, Issue:12

    Topics: Acute Kidney Injury; Acyl-CoA Dehydrogenase; Carnitine; Child, Preschool; Female; Glucose; Humans; H

2009
Protective effect of L-carnitine versus amifostine against cisplatin-induced nephrotoxicity in rats.
    Medical oncology (Northwood, London, England), 2011, Volume: 28 Suppl 1

    Topics: Acute Kidney Injury; Amifostine; Animals; Antineoplastic Agents; Carnitine; Cisplatin; Male; Rats; R

2011
The role of carnitine in preventing renal damage developed as a result of infrarenal aortic ischemia-reperfusion.
    Renal failure, 2011, Volume: 33, Issue:4

    Topics: Acute Kidney Injury; Animals; Aorta, Abdominal; Carnitine; Kidney; Male; Random Allocation; Rats; Ra

2011
Letter to the editor regarding the article by Uzunoglu et al.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Acute Kidney Injury; Amifostine; Animals; Carnitine; Cisplatin; Male

2012
Serum metabolomic profiles from patients with acute kidney injury: a pilot study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Apr-15, Volume: 893-894

    Topics: Acute Kidney Injury; Adult; Amino Acids; Biomarkers; Carnitine; Case-Control Studies; Chromatography

2012
Metabolomic changes and protective effect of (L)-carnitine in rat kidney ischemia/reperfusion injury.
    Kidney & blood pressure research, 2012, Volume: 35, Issue:5

    Topics: Acute Kidney Injury; Animals; Carnitine; Disease Models, Animal; Energy Metabolism; Male; Malondiald

2012
Hemolytic uremic syndrome (HUS) secondary to cobalamin C (cblC) disorder.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:12

    Topics: Acute Kidney Injury; Betaine; Brain Diseases, Metabolic, Inborn; Carnitine; Carrier Proteins; Combin

2007
[Lipid metabolism and lipid utilization in renal failure].
    Infusionstherapie und klinische Ernahrung, 1983, Volume: 10, Issue:4

    Topics: Acute Kidney Injury; Carnitine; Cholesterol; Energy Metabolism; Fat Emulsions, Intravenous; Humans;

1983
[Fat and renal failure--therapeutic aspects].
    Klinische Wochenschrift, 1982, Volume: 60, Issue:15

    Topics: Acute Kidney Injury; Animals; Bezafibrate; Carnitine; Charcoal; Clofibrate; Clofibric Acid; Humans;

1982
A disorder of muscle lipid metabolism and myoglobinuria. Absence of carnitine palmityl transferase.
    The New England journal of medicine, 1975, Feb-27, Volume: 292, Issue:9

    Topics: Acute Kidney Injury; Acyltransferases; Adolescent; Adult; Carnitine; Cholesterol; Creatine Kinase; F

1975
Carnitine and carnitine esters in acute renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:11

    Topics: Acute Kidney Injury; Animals; Carnitine; Esters; Female; Humans; Kidney; Liver; Male; Muscles; Rats;

1989