carnitine has been researched along with Acquired Immunodeficiency Syndrome in 8 studies
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of zidovudine (AZT) for the treatment of acquired immunodeficiency syndrome (AIDS) induces a DNA-depleting mitochondrial myopathy, which is histologically characterized by the presence of muscle fibers with "ragged-red"-like features, red-rimmed or empty cracks, granular degeneration, and rods (AZT fibers)." | 3.69 | Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage. ( Bernardini, I; Dalakas, MC; Gahl, WA; Jay, CA; Leon-Monzon, ME, 1994) |
| "Twenty male patients with advanced AIDS (Centers for Disease Control and Prevention stage IVCI) and normal serum levels of carnitines were enrolled." | 2.67 | Carnitine depletion in peripheral blood mononuclear cells from patients with AIDS: effect of oral L-carnitine. ( De Simone, C; Famularo, G; Moretti, S; Sorice, F; Trinchieri, V; Tzantzoglou, S, 1994) |
| "Carnitine deficiency was suspected in study participants prior to data collection because of previously reported cardiac symptoms, muscle weakness, hypometabolism and/or cachexia." | 1.28 | L-carnitine deficiency in AIDS patients. ( De Simone, C; Jirillo, E; Martelli, EA; Marzo, A; Tzantzoglou, S; Vullo, V, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Famularo, G | 5 |
| De Simone, C | 7 |
| Tzantzoglou, S | 3 |
| Trinchieri, V | 1 |
| Moretti, S | 5 |
| Sorice, F | 1 |
| Dalakas, MC | 1 |
| Leon-Monzon, ME | 1 |
| Bernardini, I | 1 |
| Gahl, WA | 1 |
| Jay, CA | 1 |
| Paoletti, F | 1 |
| Vullo, V | 2 |
| Delia, S | 1 |
| Cifone, MG | 2 |
| Alesse, E | 3 |
| Di Marzio, L | 2 |
| Ruggeri, B | 1 |
| Zazzeroni, F | 1 |
| Steinberg, SM | 1 |
| Vullo, E | 1 |
| Roncaioli, P | 1 |
| Muzi, P | 1 |
| Marcellini, S | 2 |
| Amicosante, G | 1 |
| Jirillo, E | 1 |
| Marzo, A | 1 |
| Martelli, EA | 1 |
1 review available for carnitine and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Cellular dysmetabolism: the dark side of HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Apoptosis; Carnitine; Ceramides; Glutamic Acid; HIV-1; Humans | 1996 |
2 trials available for carnitine and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Carnitine depletion in peripheral blood mononuclear cells from patients with AIDS: effect of oral L-carnitine.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Carnitine; CD4-Positive T-Lymphocyt | 1994 |
High dose L-carnitine improves immunologic and metabolic parameters in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; beta 2-Microglobulin; Carnitine; Humans; Lymphocyte Activ | 1993 |
5 other studies available for carnitine and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
A new era for carnitine?
Topics: Acquired Immunodeficiency Syndrome; Carnitine; Fatigue Syndrome, Chronic; Humans; Shock, Septic | 1995 |
Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage.
Topics: Acquired Immunodeficiency Syndrome; Adult; Carnitine; Humans; Lipid Metabolism; Male; Middle Aged; M | 1994 |
Effect of L-carnitine treatment in vivo on apoptosis and ceramide generation in peripheral blood lymphocytes from AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Apoptosis; Carnitine; CD4-Positive T-Lymphocytes; CD8-Pos | 1997 |
Influence of L-carnitine on CD95 cross-lining-induced apoptosis and ceramide generation in human cell lines: correlation with its effects on purified acidic and neutral sphingomyelinases in vitro.
Topics: Acquired Immunodeficiency Syndrome; Apoptosis; Carnitine; Cell Line; Ceramides; Cross-Linking Reagen | 1997 |
L-carnitine deficiency in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Carnitine; Female; Humans; Male; Vitamin B Deficiency | 1992 |