carnitine has been researched along with Acidosis, Lactic in 23 studies
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our first objective was to determine a blood lactate threshold predictive of survival in human immunodeficiency virus patients experiencing lactic acidosis related to nucleoside analogs, and second, to test l-carnitine for the treatment of patients exceeding that threshold." | 9.10 | Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine. ( Azoulay, E; Branche, F; Cariou, A; Claessens, YE; Dhainaut, JF; Goldgran-Toledano, D; Monchi, M; Rouges, P; Soufir, L, 2003) |
| " NRTIs can induce mitochondrial impairment that leads to a number of adverse events, including symptomatic lactic acidosis." | 8.82 | Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. ( Cariou, A; Chiche, JD; Claessens, YE; Mira, JP, 2003) |
| "We intended to find out the effectiveness of lactic acidosis therapy for mitochondrial toxicity." | 7.73 | [Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors]. ( Deig, E; Garrabou, G; Miró, O; Pedrol, E; Ribell, M; Soler, A; Villà, Mdel C, 2005) |
| "Treatment with thiamine and carnitine resulted in a decrease in blood lactate to normal levels and a dramatic clinical improvement." | 5.28 | Neonatal cardiomyopathy and lactic acidosis responsive to thiamine. ( Abeling, NG; Bakker, HD; Lam, J; Luyt-Houwen, IE; Scholte, HR; van Gennip, AH, 1991) |
| "Our first objective was to determine a blood lactate threshold predictive of survival in human immunodeficiency virus patients experiencing lactic acidosis related to nucleoside analogs, and second, to test l-carnitine for the treatment of patients exceeding that threshold." | 5.10 | Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine. ( Azoulay, E; Branche, F; Cariou, A; Claessens, YE; Dhainaut, JF; Goldgran-Toledano, D; Monchi, M; Rouges, P; Soufir, L, 2003) |
| "To verify the efficacy and absence of risk attributable to therapy with alkaline solutions for correction of lactic acidosis and to demonstrate the usefulness of L-carnitine in converting lactate into pyruvate in conditions of good blood oxygenation." | 5.07 | [Intraoperative lactic acidosis, can it be treated? Clinico-experimental, prospective, sequential study]. ( Adrario, E; Caporelli, S; De Pace, F; Donati, A; Frezzotti, AR; Giovannini, C; Luzi, A; Munch, C; Pietropaoli, P, 1994) |
| " NRTIs can induce mitochondrial impairment that leads to a number of adverse events, including symptomatic lactic acidosis." | 4.82 | Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. ( Cariou, A; Chiche, JD; Claessens, YE; Mira, JP, 2003) |
| "We intended to find out the effectiveness of lactic acidosis therapy for mitochondrial toxicity." | 3.73 | [Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors]. ( Deig, E; Garrabou, G; Miró, O; Pedrol, E; Ribell, M; Soler, A; Villà, Mdel C, 2005) |
| " The initial patient, and later her newborn sibling, had mildly dysmorphic features, lactic acidosis and a defect in mitochondrial respiratory complex II associated with many biochemical features of a block in fatty acid oxidation." | 3.72 | Respiratory complex II defect in siblings associated with a symptomatic secondary block in fatty acid oxidation. ( Bocian, M; Boyle, K; Gargus, JJ; Roe, CR; Roe, DS; Vianey-Saban, C, 2003) |
| "The valproic acid plasma level was very high (1437 μg/mL), confirming it was a severe intoxication." | 1.37 | [Acute valproic acid intoxication: interest of a treatment by extracoporeal elimination combined with L-carnitine]. ( Alluin, A; Canevet, C; Desmaretz, JL; Gauthier, N; Jezequel, J, 2011) |
| "Treatment with thiamine and carnitine resulted in a decrease in blood lactate to normal levels and a dramatic clinical improvement." | 1.28 | Neonatal cardiomyopathy and lactic acidosis responsive to thiamine. ( Abeling, NG; Bakker, HD; Lam, J; Luyt-Houwen, IE; Scholte, HR; van Gennip, AH, 1991) |
| "The carnitine concentration was diminished in blood and muscle tissue." | 1.27 | Mitochondrial myopathy with lactic acidaemia, Fanconi-De Toni-Debré syndrome and a disturbed succinate: cytochrome c oxidoreductase activity. ( Guggenbichler, JP; Ruitenbeek, W; Sengers, RC; Sperl, W; Stadhouders, AM; Trijbels, JM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 9 (39.13) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatia, M | 1 |
| Smeltz, AM | 1 |
| Desai, CS | 1 |
| Arora, H | 1 |
| Kumar, PA | 1 |
| Almannai, M | 1 |
| Aldehaimi, A | 1 |
| Peake, RWA | 1 |
| Almontashiri, NAM | 1 |
| Pérez-Dueñas, B | 1 |
| Serrano, M | 1 |
| Rebollo, M | 1 |
| Muchart, J | 1 |
| Gargallo, E | 1 |
| Dupuits, C | 1 |
| Artuch, R | 1 |
| Orsucci, D | 1 |
| Filosto, M | 1 |
| Siciliano, G | 1 |
| Mancuso, M | 1 |
| Alluin, A | 1 |
| Jezequel, J | 1 |
| Gauthier, N | 1 |
| Desmaretz, JL | 1 |
| Canevet, C | 1 |
| Davison, AS | 1 |
| Milan, AM | 1 |
| Roberts, NB | 1 |
| Claessens, YE | 3 |
| Cariou, A | 3 |
| Monchi, M | 1 |
| Soufir, L | 1 |
| Azoulay, E | 1 |
| Rouges, P | 1 |
| Goldgran-Toledano, D | 1 |
| Branche, F | 1 |
| Dhainaut, JF | 2 |
| Chiche, JD | 2 |
| Mira, JP | 1 |
| Gargus, JJ | 1 |
| Boyle, K | 1 |
| Bocian, M | 1 |
| Roe, DS | 1 |
| Vianey-Saban, C | 1 |
| Roe, CR | 1 |
| Carter, RW | 1 |
| Singh, J | 1 |
| Archambault, C | 1 |
| Arrieta, A | 1 |
| Pedrol, E | 1 |
| Ribell, M | 1 |
| Deig, E | 1 |
| Villà, Mdel C | 1 |
| Miró, O | 1 |
| Garrabou, G | 1 |
| Soler, A | 1 |
| Oglesbee, D | 1 |
| Freedenberg, D | 1 |
| Kramer, KA | 1 |
| Anderson, BD | 1 |
| Hahn, SH | 1 |
| Pietropaoli, P | 1 |
| Caporelli, S | 1 |
| De Pace, F | 1 |
| Donati, A | 1 |
| Adrario, E | 1 |
| Luzi, A | 1 |
| Munch, C | 1 |
| Giovannini, C | 1 |
| Frezzotti, AR | 1 |
| Dawson, DB | 1 |
| Waber, L | 1 |
| Hale, DE | 1 |
| Bennett, MJ | 1 |
| Elpeleg, ON | 1 |
| Ruitenbeek, W | 3 |
| Jakobs, C | 1 |
| Barash, V | 1 |
| De Vivo, DC | 1 |
| Amir, N | 1 |
| Bakker, HD | 2 |
| Scholte, HR | 2 |
| Jeneson, JA | 1 |
| Busch, HF | 1 |
| Abeling, NG | 2 |
| van Gennip, AH | 2 |
| Dauriat, G | 1 |
| Brinkman, K | 1 |
| Vrouenraets, S | 1 |
| Kauffmann, R | 1 |
| Weigel, H | 1 |
| Frissen, J | 1 |
| Cammann, R | 1 |
| Dunker, H | 1 |
| Schumacher, H | 1 |
| Sperner, J | 1 |
| Luyt-Houwen, IE | 1 |
| Lam, J | 1 |
| Sperl, W | 1 |
| Trijbels, JM | 1 |
| Sengers, RC | 1 |
| Stadhouders, AM | 1 |
| Guggenbichler, JP | 1 |
| Kitano, A | 1 |
| Nishiyama, S | 1 |
| Miike, T | 1 |
| Hattori, S | 1 |
| Ohtani, Y | 1 |
| Matsuda, I | 1 |
| Dionisi Vici, C | 1 |
| Bertini, E | 1 |
| Bartuli, A | 1 |
| Sabetta, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of the Efficacy of a Combination of Antioxidants and B Vitamins in Preventing the Recurrence of Hyperlactatemia in Subjects Who Have Limited Antiretroviral Options[NCT00037063] | 0 participants (Actual) | Interventional | Withdrawn | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for carnitine and Acidosis, Lactic
| Article | Year |
|---|---|
Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction.
Topics: Acidosis, Lactic; Animals; Antioxidants; Carnitine; Creatine; Dietary Supplements; Electron Transpor | 2009 |
Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors.
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Carnitine; HIV Infections; Humans; Lactic Acid; Mitochondr | 2003 |
2 trials available for carnitine and Acidosis, Lactic
| Article | Year |
|---|---|
Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine.
Topics: Acidosis, Lactic; Adult; Antiviral Agents; Carnitine; Female; HIV Infections; Humans; Lactic Acid; M | 2003 |
[Intraoperative lactic acidosis, can it be treated? Clinico-experimental, prospective, sequential study].
Topics: Acidosis, Lactic; Bicarbonates; Carnitine; Humans; Intraoperative Complications; Prospective Studies | 1994 |
19 other studies available for carnitine and Acidosis, Lactic
| Article | Year |
|---|---|
Treatment of type B lactic acidosis with N-acetylcysteine and levocarnitine.
Topics: Acetylcysteine; Acidosis, Lactic; Carnitine; Humans | 2023 |
Hyperammonemia, Lactic Acidosis, and Arrhythmia in a Newborn.
Topics: Acidosis, Lactic; Arrhythmias, Cardiac; Carnitine; Female; Humans; Hyperammonemia; Infant, Newborn; | 2021 |
Reversible lactic acidosis in a newborn with thiamine transporter-2 deficiency.
Topics: Acidosis, Lactic; Biotin; Blood Chemical Analysis; Carnitine; Diagnosis, Differential; Drug Therapy, | 2013 |
[Acute valproic acid intoxication: interest of a treatment by extracoporeal elimination combined with L-carnitine].
Topics: Acidosis, Lactic; Acute Lung Injury; Anticonvulsants; Carnitine; Cranial Nerve Diseases; Electroence | 2011 |
The consequences of valproate overdose.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Anticonvulsants; Carnitine; Drug Overdose; Epilepsy; | 2011 |
Respiratory complex II defect in siblings associated with a symptomatic secondary block in fatty acid oxidation.
Topics: Acidosis, Lactic; Acyl-CoA Dehydrogenase; Behavior; Bicarbonates; Carnitine; Cell Line; Fatty Acids; | 2003 |
Severe lactic acidosis in association with reverse transcriptase inhibitors with potential response to L-carnitine in a pediatric HIV-positive patient.
Topics: Acidosis, Lactic; Carnitine; Child; Humans; Male; Reverse Transcriptase Inhibitors | 2004 |
[Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors].
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Carnitine; HIV Infections; Humans; Lactic Acid; Male; Midd | 2005 |
Normal muscle respiratory chain enzymes can complicate mitochondrial disease diagnosis.
Topics: Acidosis, Lactic; Atrophy; Biopsy; Blotting, Western; Carnitine; Central Nervous System Cysts; Cereb | 2006 |
Transient organic aciduria and persistent lacticacidemia in a patient with short-chain acyl-coenzyme A dehydrogenase deficiency.
Topics: Acidosis, Lactic; Carnitine; Fatty Acid Desaturases; Humans; Infant, Newborn; Riboflavin | 1995 |
Congenital lacticacidemia caused by lipoamide dehydrogenase deficiency with favorable outcome.
Topics: Acidosis, Lactic; Carnitine; Dichloroacetic Acid; Dihydrolipoamide Dehydrogenase; Fibroblasts; Human | 1995 |
Vitamin-responsive complex I deficiency in a myopathic patient with increased activity of the terminal respiratory chain and lactic acidosis.
Topics: Acidosis, Lactic; Ca(2+) Mg(2+)-ATPase; Carnitine; Child; Energy Metabolism; Female; Humans; Magneti | 1994 |
L-Carnitine as a treatment of life-threatening lactic acidosis induced by nucleoside analogues.
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Carnitine; Didanosine; Drug Therapy, Combination; HIV Infe | 2000 |
Treatment of nucleoside reverse transcriptase inhibitor-induced lactic acidosis.
Topics: Acidosis, Lactic; Ascorbic Acid; Blood Pressure; Carnitine; Drug Therapy, Combination; Humans; Repro | 2000 |
[Myopathy with carnitine deficiency and lactic acidosis. A contribution to differential diagnosis of carnitine deficiency myopathies and mitochondrial myopathies].
Topics: Acidosis, Lactic; Biopsy; Carnitine; Child; Diagnosis, Differential; Humans; Lipid Metabolism, Inbor | 1992 |
Neonatal cardiomyopathy and lactic acidosis responsive to thiamine.
Topics: Acidosis, Lactic; Cardiomyopathies; Carnitine; Child; Child, Preschool; Female; Humans; Infant; Keto | 1991 |
Mitochondrial myopathy with lactic acidaemia, Fanconi-De Toni-Debré syndrome and a disturbed succinate: cytochrome c oxidoreductase activity.
Topics: Acidosis, Lactic; Carnitine; Fanconi Syndrome; Female; Humans; Infant, Newborn; Lactates; Lactic Aci | 1988 |
Mitochondrial cytopathy with lactic acidosis, carnitine deficiency and DeToni-Fanconi-Debré syndrome.
Topics: Acidosis, Lactic; Carnitine; Electron Transport Complex IV; Fanconi Syndrome; Female; Humans; Infant | 1986 |
Carnitine in lactic acidosis.
Topics: Acidosis, Lactic; Algorithms; Carnitine; Child; Humans | 1988 |