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carmustine and Syndrome

carmustine has been researched along with Syndrome in 8 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"We report on three patients with multiple myeloma who developed drug-induced pneumonitis 1-2(1/2) months following maintenance (post autologous transplantation) chemotherapy with CDEP (cyclophosphamide, dexamethasone, etoposide, cisplatin) and 6-20 months after exposure to carmustine (BCNU) 300 mg/m(2), used in combination with melphalan 140 mg/m(2), as pre-transplant conditioning regimen."7.71Pulmonary toxicity syndrome following CDEP (cyclophosphamide, dexamethasone, etoposide, cisplatin) chemotherapy. ( Cottler-Fox, M; Fassas, A; Gojo, I; Meisenberg, B; Papadimitriou, JC; Rapoport, A; Tricot, G, 2001)
"Delayed pulmonary toxicity syndrome, characterized by interstitial pneumonia and pulmonary fibrosis, is common following high-dose bischloroethylnitrosourea (BCNU) (carmustine, [1,3-bis (2-chloroethyl)-1-nitrosourea]) containing chemotherapeutic regimens."3.72Interferon-gamma for delayed pulmonary toxicity syndrome resistant to steroids. ( Brown, KK; Cool, CD; Jones, RB; Lynch, DA; Suratt, BT, 2003)
"Our aim was to describe the incidence, clinical course, and risk factors for idiopathic pneumonia syndrome (IPS) after high-dose chemotherapy with cyclophosphamide, carmustine, and thiotepa followed by autologous stem cell transplantation for high-risk breast cancer."3.72Idiopathic pneumonia syndrome after high-dose chemotherapy and autologous hematopoietic stem cell transplantation for high-risk breast cancer. ( Champlin, RE; Giralt, SA; Rondon, G; Saliba, RM; Shannon, VR; Ueno, NT; Wong, R, 2003)
"We report on three patients with multiple myeloma who developed drug-induced pneumonitis 1-2(1/2) months following maintenance (post autologous transplantation) chemotherapy with CDEP (cyclophosphamide, dexamethasone, etoposide, cisplatin) and 6-20 months after exposure to carmustine (BCNU) 300 mg/m(2), used in combination with melphalan 140 mg/m(2), as pre-transplant conditioning regimen."3.71Pulmonary toxicity syndrome following CDEP (cyclophosphamide, dexamethasone, etoposide, cisplatin) chemotherapy. ( Cottler-Fox, M; Fassas, A; Gojo, I; Meisenberg, B; Papadimitriou, JC; Rapoport, A; Tricot, G, 2001)
"The incidence of PTS in breast cancer patients treated with a BCNU-containing HDC regimen can be remarkably high."1.31Pulmonary toxicity syndrome in breast cancer patients undergoing BCNU-containing high-dose chemotherapy and autologous hematopoietic cell transplantation. ( Blume, KG; Cao, TM; Hu, WW; Johnston, LJ; Negrin, RS; Rizk, NW; Shizuru, JA; Stockerl-Goldstein, KE; Taylor, TL; Wong, RM, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lavolé, J1
Le Goff, M1
Oudjit, A1
Sogni, P1
Mallet, V1
Suratt, BT1
Lynch, DA1
Cool, CD1
Jones, RB1
Brown, KK1
Wong, R1
Rondon, G1
Saliba, RM1
Shannon, VR1
Giralt, SA1
Champlin, RE1
Ueno, NT1
Gomez, GA1
Aggarwal, KK1
Han, T1
Rubio, C1
Hill, ME1
Milan, S1
O'Brien, ME1
Cunningham, D1
Cao, TM1
Negrin, RS1
Stockerl-Goldstein, KE1
Johnston, LJ1
Shizuru, JA1
Taylor, TL1
Rizk, NW1
Wong, RM1
Blume, KG1
Hu, WW1
Fassas, A1
Gojo, I1
Rapoport, A1
Cottler-Fox, M1
Meisenberg, B1
Papadimitriou, JC1
Tricot, G1
Schuler, D1
Koós, R1
Krauze, I1
Péter, A1

Trials

1 trial available for carmustine and Syndrome

ArticleYear
Post-therapeutic acute malignant myeloproliferative syndrome and acute nonlymphocytic leukemia in non-Hodgkin's lymphoma.
    Cancer, 1982, Dec-01, Volume: 50, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Administration Schedule; Drug

1982

Other Studies

7 other studies available for carmustine and Syndrome

ArticleYear
Abdominal computed tomography angiography in post-transplantation sinusoidal obstruction syndrome associated with R-DHAOX/BEAM toxicity.
    British journal of haematology, 2018, Volume: 180, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Computed Tomography Angiography; C

2018
Interferon-gamma for delayed pulmonary toxicity syndrome resistant to steroids.
    Bone marrow transplantation, 2003, Volume: 31, Issue:10

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2003
Idiopathic pneumonia syndrome after high-dose chemotherapy and autologous hematopoietic stem cell transplantation for high-risk breast cancer.
    Bone marrow transplantation, 2003, Volume: 31, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carmustine; Cyclophosphamid

2003
Idiopathic pneumonia syndrome after high-dose chemotherapy for relapsed Hodgkin's disease.
    British journal of cancer, 1997, Volume: 75, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Carmustine; Female; Hodgkin Disease; Humans; M

1997
Pulmonary toxicity syndrome in breast cancer patients undergoing BCNU-containing high-dose chemotherapy and autologous hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemot

2000
Pulmonary toxicity syndrome following CDEP (cyclophosphamide, dexamethasone, etoposide, cisplatin) chemotherapy.
    Bone marrow transplantation, 2001, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modality Thera

2001
Paraneoplastic syndrome in childhood.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1977, Volume: 18, Issue:1

    Topics: Brain Diseases; Carmustine; Child, Preschool; Humans; Lomustine; Male; Mediastinal Neoplasms; Methot

1977