carmustine has been researched along with Sarcoma in 9 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In nine of 11 (82%) instances, tumors were sensitive to a particular drug, and the patient had at least 50% regression of tumor following treatment with the tested drug." | 1.26 | Clinical correlations with drug sensitivities in the clonogenic assay: a retrospective study. ( Burk, MW; Campbell, MA; Giuliano, AE; Kaiser, LR; Kern, DH; Mann, BD; Morton, DL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryan, CW | 1 |
| Dolan, ME | 1 |
| Brockstein, BB | 1 |
| McLendon, R | 1 |
| Delaney, SM | 1 |
| Samuels, BL | 1 |
| Agamah, ES | 1 |
| Vokes, EE | 1 |
| Mann, BD | 1 |
| Kern, DH | 1 |
| Giuliano, AE | 1 |
| Burk, MW | 1 |
| Campbell, MA | 1 |
| Kaiser, LR | 1 |
| Morton, DL | 1 |
| Robustelli della Cuna, G | 1 |
| Paoletti, P | 1 |
| Bernardo, G | 1 |
| Knerich, R | 1 |
| Butti, G | 1 |
| Cuzzoni, Q | 1 |
| Mahaley, MS | 1 |
| Gentry, RE | 1 |
| Bigner, DD | 1 |
| Slavik, M | 1 |
| Peters, WP | 1 |
| Eder, JP | 1 |
| Henner, WD | 1 |
| Schryber, S | 1 |
| Wilmore, D | 1 |
| Finberg, R | 1 |
| Schoenfeld, D | 1 |
| Bast, R | 1 |
| Gargone, B | 1 |
| Antman, K | 1 |
| Yardumian, H | 1 |
| Marsh, JC | 1 |
| DeConti, RC | 1 |
| Hubbard, SP | 1 |
| Schein, PS | 1 |
| O'Connell, MJ | 1 |
| Blom, J | 1 |
| Hubbard, S | 1 |
| Magrath, IT | 1 |
| Bergevin, P | 1 |
| Wiernik, PH | 1 |
| Ziegler, JL | 1 |
| DeVita, VT | 1 |
1 review available for carmustine and Sarcoma
| Article | Year |
|---|---|
Solid tumor chemotherapy: new drugs and horizons.
Topics: Antineoplastic Agents; Bleomycin; Breast Neoplasms; Carmustine; Doxorubicin; Drug Therapy, Combinati | 1974 |
3 trials available for carmustine and Sarcoma
| Article | Year |
|---|---|
A phase II trial of O6-benzylguanine and carmustine in patients with advanced soft tissue sarcoma.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Enzyme Inhibitors; | 2006 |
Treatment of Hodgkin's disease and other cancers with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962).
Topics: Adenocarcinoma; Adenoma, Islet Cell; Adolescent; Adrenal Gland Neoplasms; Adult; Alkylating Agents; | 1971 |
Clinical antitumor activity and toxicity of streptozotocin (NSC-85998).
Topics: Adenoma, Islet Cell; Blood Cells; Burkitt Lymphoma; Carcinoid Tumor; Carmustine; Clinical Trials as | 1974 |
5 other studies available for carmustine and Sarcoma
| Article | Year |
|---|---|
Clinical correlations with drug sensitivities in the clonogenic assay: a retrospective study.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Hepatocellular; Carmustine; Cell Division; D | 1982 |
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma; | 1982 |
Immunobiology of primary intracranial tumors.
Topics: Alpharetrovirus; Animals; Astrocytoma; BCG Vaccine; Brain Neoplasms; Carmustine; Disease Models, Ani | 1977 |
Clinical studies with nitrosoureas in various solid tumors.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, F | 1976 |
High-dose combination alkylating agents with autologous bone marrow support: a Phase 1 trial.
Topics: Adult; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantatio | 1986 |