Page last updated: 2024-10-24

carmustine and Renal Insufficiency

carmustine has been researched along with Renal Insufficiency in 3 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"One patient had a retinal vein thrombosis."2.39Hemolytic uremic syndrome after high dose chemotherapy with autologous stem cell support. ( Baars, JW; de Glas-Vos, CW; Rodenhuis, S; Thomas, BL; van der Lelie, H; van Dijk, MA; van Oers, RH; von dem Borne, AE, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Farnault, L1
Venton, G1
Pourroy, B1
Jourde-Chiche, N1
Ivanov, V1
Arcani, R1
Roche, P1
Mercier, C1
Colle, J1
Fanciullino, R1
Costello, RT1
van der Lelie, H1
Baars, JW1
Rodenhuis, S1
van Dijk, MA1
de Glas-Vos, CW1
Thomas, BL1
van Oers, RH1
von dem Borne, AE1
Merouani, A1
Shpall, EJ1
Jones, RB1
Archer, PG1
Schrier, RW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention Of Nephrotoxicity Following Allogeneic Bone Marrow Transplantation Using Urodilatin (Ularitide,Atrial Natriuretic Peptide) and Mannitol.[NCT00390624]Phase 220 participants (Anticipated)Interventional2003-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for carmustine and Renal Insufficiency

ArticleYear
Hemolytic uremic syndrome after high dose chemotherapy with autologous stem cell support.
    Cancer, 1995, Dec-01, Volume: 76, Issue:11

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; An

1995

Trials

1 trial available for carmustine and Renal Insufficiency

ArticleYear
Renal function in high dose chemotherapy and autologous hematopoietic cell support treatment for breast cancer.
    Kidney international, 1996, Volume: 50, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic;

1996

Other Studies

1 other study available for carmustine and Renal Insufficiency

ArticleYear
Severe renal insufficiency is not an absolute pitfall to autologous stem cell transplantation with BeEAM (bendamustine, etoposide, cytarabine, melphalan) conditioning regimen.
    Bone marrow transplantation, 2019, Volume: 54, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Autografts; Carmustine; Cytarabine; Humans; L

2019