Page last updated: 2024-10-24

carmustine and Plasmacytoma

carmustine has been researched along with Plasmacytoma in 16 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Plasmacytoma: Any discrete, presumably solitary, mass of neoplastic PLASMA CELLS either in BONE MARROW or various extramedullary sites.

Research Excerpts

ExcerptRelevanceReference
"Twenty-eight patients with multiple myeloma have been treated with a quadruple chemotherapeutic regimen consisting of 1, 3 bis (2-chloroethyl)-1-nitrosourea (BCNU), cyclophosphamide, melphalan, and prednisolone."5.04Combination therapy for myelomatosis. ( Azam, L; Delamore, IW, 1974)
"One hundred and eighteen patients with multiple myeloma had stem cells collected and cryopreserved."1.30Early harvest and late transplantation as an effective therapeutic strategy in multiple myeloma. ( Chen, MG; Gastineau, DA; Gertz, MA; Greipp, PR; Inwards, DJ; Kyle, RA; Lacy, MQ; Litzow, MR; Lust, JA; Pineda, AA; Tefferi, A; Witzig, TE, 1999)
"Murine LPC-1 plasmacytoma is sensitive to treatment with cyclophosphamide (CY), and animals bearing this tumor in advanced stages can be cured with doses as small as 60 mg/kg."1.26Development and characterization of a cyclophosphamide-resistant mouse plasmacytoma cell line. ( Frondoza, CG; Humphrey, RL; Trivedi, SM, 1982)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's3 (18.75)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Mouhieddine, TH1
Barlogie, B1
Teruya-Feldstein, J1
Hou, TY1
Dai, MS1
Kao, WY1
Grussendorf, M2
Waldherr, R1
Seelig, HP1
Ritz, E1
Frondoza, CG1
Trivedi, SM1
Humphrey, RL1
Clemens, MR1
Frank, H1
Remmer, H1
Waller, HD1
Ghanta, VK1
Hiramoto, RN1
Davis, DW1
Hiramoto, NS1
Antonijevic, N1
Radosevic-Radojkovic, N1
Colovic, M1
Jovanovic, V1
Rolovic, Z1
Colović, MD1
Janković, GM1
Colović, RB1
Martinović-Cemerikić, VM1
Gertz, MA1
Lacy, MQ1
Inwards, DJ1
Chen, MG1
Pineda, AA1
Gastineau, DA1
Greipp, PR1
Lust, JA1
Tefferi, A1
Witzig, TE1
Kyle, RA1
Litzow, MR1
Fremiotti, A1
Castellani, R1
Barbatano, L1
Salerno, L1
Bartolini, M1
Obrecht, JP1
Hiramoto, R1
Ghanta, V1
Durant, JR1
Stanislawski, M1
Rousseau, V1
Goavec, M1
Ito, H1
Berko, R1
Seissman, K1
Colvin, M1
Bocian, RC1
Ben-Efraim, S1
Dray, S1
Azam, L1
Delamore, IW1
Wheeler, GP1
Alexander, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
HIGH-DOSE MELPHALAN CHEMOTHERAPY AND TOTAL BODY RADIATION WITH PERIPHERAL BLOOD STEM-CELL RECONSTITUTION FOR PATIENTS WITH RELAPSING MULTIPLE MYELOMA[NCT00002630]Phase 250 participants (Anticipated)Interventional1993-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for carmustine and Plasmacytoma

ArticleYear
Combination therapy for myelomatosis.
    British medical journal, 1974, Dec-07, Volume: 4, Issue:5944

    Topics: Bone Marrow Examination; Calcium; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Thera

1974

Other Studies

15 other studies available for carmustine and Plasmacytoma

ArticleYear
Hemophagocytic relapsed intramedullary plasmacytoma.
    International journal of hematology, 2020, Volume: 111, Issue:6

    Topics: Adult; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bo

2020
Testicular plasmacytoma with bone dissemination without medullary plasmacytosis.
    Annals of hematology, 2003, Volume: 82, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined C

2003
[Systemic light-chain disease as a complication of plasmacytoma].
    Deutsche medizinische Wochenschrift (1946), 1984, Sep-14, Volume: 109, Issue:37

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bence Jones Protein; Bone Marrow Cells; Carmustine;

1984
Development and characterization of a cyclophosphamide-resistant mouse plasmacytoma cell line.
    Cancer treatment reports, 1982, Volume: 66, Issue:7

    Topics: Animals; Carmustine; Cell Division; Cell Line; Clone Cells; Cyclophosphamide; DNA, Neoplasm; Drug Re

1982
Vinylchloride: decomposition product of BCNU in vivo and in vitro.
    Cancer chemotherapy and pharmacology, 1982, Volume: 10, Issue:1

    Topics: Breath Tests; Carmustine; Chemical Phenomena; Chemistry; Drug Stability; Gas Chromatography-Mass Spe

1982
Maintenance of MOPC 104E myeloma in plateau phase.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Cyclophosphamide; Dose-Response Relationship,

1980
Multifocal plasmacytoma of hand and foot bones.
    Leukemia & lymphoma, 1996, Volume: 21, Issue:5-6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carmustine; Combined Modality

1996
Non-secretory solitary plasmacytoma of the spleen.
    Medical oncology (Northwood, London, England), 1998, Volume: 15, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Humans; Male; Melphala

1998
Early harvest and late transplantation as an effective therapeutic strategy in multiple myeloma.
    Bone marrow transplantation, 1999, Volume: 23, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Bone Marrow; Carm

1999
[Interim results of the combination of M2 polychemotherapy with calcitonin and synthetic anabolic agents in the treatment of plasmacytoma].
    Recenti progressi in medicina, 1979, Volume: 66, Issue:4

    Topics: Aged; Anabolic Agents; Antineoplastic Agents; Calcitonin; Carmustine; Cyclophosphamide; Dihydrotesto

1979
[Results of plasmacytoma therapy of ALGB (acute leukemia group B)].
    Hamatologie und Bluttransfusion, 1976, Volume: 18

    Topics: Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Humans; Melphalan; M

1976
Evaluation of a cooperative group human myeloma protocol using the MOPC 104E myeloma model.
    Cancer research, 1975, Volume: 35, Issue:5

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Line; Cell Survival; Cyclophosphamide; Disease Mode

1975
Immunotoxins containing glucose oxidase and lactoperoxidase with tumoricidal properties: in vitro killing effectiveness in a mouse plasmacytoma cell model.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Animals; Bone Marrow; Buthionine Sulfoximine; Carmustine; Dose-Response Relationship, Immunologic; D

1989
Tumoricidal and immunomodulatory activities of drugs and implications for therapy of mice bearing a late stage MOPC-315 plasmacytoma.
    International journal of immunopharmacology, 1988, Volume: 10, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Carmustine; Cell Division; Cyclophosphamide;

1988
Duration of inhibition of synthesis of DNA in tumors and host tissues after single doses of nitrosoureas.
    Cancer research, 1974, Volume: 34, Issue:8

    Topics: Animals; Bone Marrow; Brain; Carmustine; Cricetinae; Cyclohexanes; Depression, Chemical; DNA, Neopla

1974