carmustine has been researched along with Neuroblastoma in 18 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-six children with advanced neuroblastoma were consolidated with cisplatin, BCNU, etoposide, melphalan, 21 Gy of local radiotherapy, and bone marrow rescue in a multicenter study." | 5.07 | High-dose consolidation with local radiation and bone marrow rescue in patients with advanced neuroblastoma. ( Bender-Götze, C; Burdach, S; Ebell, W; Friedrich, W; Herrmann, F; Klingebiel, T; Koscielniak, E; Kremens, B; Schmid, H; Siegert, W, 1994) |
| "Myeloablative treatment intensification in 25 patients diagnosed when older than 12 months of age with stage IV neuroblastoma included sequential delivery of cisplatin 120 mg/m2 x 1, hyperfractionated radiation (2,100 cGy) to the primary site and adjacent lymph nodes, carmustine (BCNU) 200 mg/m2 x 1, melphalan 60 mg/m2/d x 3 (n = 13) or thiotepa 300 mg/m2/d x 3." | 3.68 | Myeloablative combination chemotherapy without total body irradiation for neuroblastoma. ( Cheung, NK; Gulati, SC; Kushner, BH; LaQuaglia, M; Mandell, LR; O'Reilly, RJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franco, JL | 1 |
| Posser, T | 1 |
| Gordon, SL | 1 |
| Bobrovskaya, L | 1 |
| Schneider, JJ | 1 |
| Farina, M | 1 |
| Dafre, AL | 1 |
| Dickson, PW | 1 |
| Dunkley, PR | 1 |
| Hettiarachchi, NT | 1 |
| Wilkinson, JA | 1 |
| Boyle, JP | 1 |
| Peers, C | 1 |
| Kremens, B | 2 |
| Klingebiel, T | 1 |
| Herrmann, F | 1 |
| Bender-Götze, C | 1 |
| Burdach, S | 1 |
| Ebell, W | 1 |
| Friedrich, W | 1 |
| Koscielniak, E | 1 |
| Schmid, H | 1 |
| Siegert, W | 2 |
| Cheung, NK | 2 |
| Cheung, IY | 1 |
| Canete, A | 1 |
| Yeh, SJ | 1 |
| Kushner, B | 1 |
| Bonilla, MA | 1 |
| Heller, G | 1 |
| Larson, SM | 1 |
| Philip, T | 4 |
| Ladenstein, R | 2 |
| Zucker, JM | 3 |
| Pinkerton, R | 1 |
| Bouffet, E | 4 |
| Louis, D | 1 |
| Bernard, JL | 2 |
| Frappaz, D | 1 |
| Coze, C | 2 |
| Buckman, TD | 1 |
| Sutphin, MS | 1 |
| Mitrovic, B | 1 |
| Finklestein, JZ | 1 |
| Tittle, K | 1 |
| Rubenstein, J | 1 |
| Meshnik, R | 1 |
| Weiner, J | 1 |
| Padulles, J | 1 |
| Prats, J | 1 |
| Martínez-Mora, J | 1 |
| Boix Ochoa, J | 1 |
| Ferres, F | 1 |
| Schuler, D | 1 |
| Koós, R | 1 |
| Krauze, I | 1 |
| Péter, A | 1 |
| Slavik, M | 1 |
| Sufrin, G | 1 |
| Murphy, P | 1 |
| Michon, J | 1 |
| Gentet, JC | 2 |
| Lopez, M | 1 |
| Philip, I | 2 |
| Lasset, C | 1 |
| Brunat-Mentigny, M | 2 |
| Biron, P | 1 |
| Chauvin, F | 1 |
| Kushner, BH | 1 |
| O'Reilly, RJ | 1 |
| Mandell, LR | 1 |
| Gulati, SC | 1 |
| LaQuaglia, M | 1 |
| Carrie, C | 1 |
| Farge, A | 1 |
| Meziane, F | 1 |
| Hartmann, O | 3 |
| Benhamou, E | 3 |
| Beaujean, F | 3 |
| Kalifa, C | 3 |
| Lejars, O | 2 |
| Patte, C | 2 |
| Behard, C | 2 |
| Flamant, F | 2 |
| Thyss, A | 2 |
| Deville, A | 2 |
| Bayle, C | 1 |
| Lemerle, J | 1 |
6 trials available for carmustine and Neuroblastoma
| Article | Year |
|---|---|
High-dose consolidation with local radiation and bone marrow rescue in patients with advanced neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Ca | 1994 |
Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: the LMCE2 study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin | 1993 |
[Survival of children and results obtained with a new chemotherapic combination in disseminated neuroblastoma treatment (author's transl)].
Topics: Antineoplastic Agents; Carmustine; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphami | 1976 |
Clinical studies with DTIC (NSC-45388) in various malignancies.
Topics: Adult; Carmustine; Child; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Comb | 1976 |
Single or double consolidation treatment according to remission status after initial therapy in metastatic neuroblastoma: first results of LMCE 3 study in 40 patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Carmustine | 1991 |
A single center experience with bone marrow transplantation for high risk neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Carmustine | 1991 |
12 other studies available for carmustine and Neuroblastoma
| Article | Year |
|---|---|
Expression of tyrosine hydroxylase increases the resistance of human neuroblastoma cells to oxidative insults.
Topics: Apoptosis; Carmustine; Catalase; Cell Line, Tumor; Cell Survival; Dopamine; Dose-Response Relationsh | 2010 |
Hypoxic remodelling of Ca2+signalling in SH-SY5Y cells: influence of glutathione.
Topics: Bradykinin; Buthionine Sulfoximine; Calcium Signaling; Carmustine; Cell Line, Tumor; Cell Survival; | 2007 |
Antibody response to murine anti-GD2 monoclonal antibodies: correlation with patient survival.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibody Formation; Antineoplastic Comb | 1994 |
Oxidative stress in a clonal cell line of neuronal origin: effects of antioxidant enzyme modulation.
Topics: Animals; Brain; Carmustine; Catalase; Cell Fractionation; Cell Survival; Clone Cells; Cytosol; Gliom | 1993 |
Combination chemotherapy in murine neuroblastoma.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Disease Models, Animal; Dox | 1976 |
Paraneoplastic syndrome in childhood.
Topics: Brain Diseases; Carmustine; Child, Preschool; Humans; Lomustine; Male; Mediastinal Neoplasms; Methot | 1977 |
Pharmacokinetic studies in the chemotherapy of neuroblastoma using the C1300 murine system.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Doxorubicin | 1976 |
Myeloablative combination chemotherapy without total body irradiation for neuroblastoma.
Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation | 1991 |
Phase II studies of combinations of drugs with high dose carboplatin in neuroblastoma (800 mg/m2 to 1 g 250/m2): a report from the LMCE group.
Topics: Carboplatin; Carmustine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Co | 1988 |
[Metastatic neuroblastoma: consolidation treatment with 2 courses of high-dose chemotherapy followed by a bone marrow autograft].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Child; Chil | 1988 |
Repeated high-dose chemotherapy followed by purged autologous bone marrow transplantation as consolidation therapy in metastatic neuroblastoma.
Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Disease | 1987 |
Treatment of advanced neuroblastoma with two consecutive high-dose chemotherapy regimens and ABMT.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; | 1985 |