Page last updated: 2024-10-24

carmustine and Meningeal Neoplasms

carmustine has been researched along with Meningeal Neoplasms in 17 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.

Research Excerpts

ExcerptRelevanceReference
"At this time, methotrexate and CNS radiotherapy used together offer the best chance for prolonged remissions in children who develop overt CNS leukemia."4.76Treatment of overt CNS leukemia. ( Filler, J; Humphrey, GB; Krous, HF; Maxwell, JD; VanHoutte, JJ, 1979)
" Two doses of carmustine at intervals of one week could eradicate the disease even during the phase of logarithmic growth of the leukaemic cells, this result depending upon the level of treatment and time of dosing post-inoculation with leukaemic cells."1.27Testicular invasion and relapse and meningeal involvement in a rat T-cell leukaemia. ( Bock, M; Jackson, H; Jackson, NC; Lendon, M, 1984)
"Four cases of breast cancer with meningeal involvement are presented and a review of the literature is given."1.26[(Meningeal carcinomatosis in patients with breast cancer)]. ( Freund, M; Ostendorf, P; Waller, HD, 1979)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199013 (76.47)18.7374
1990's2 (11.76)18.2507
2000's0 (0.00)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Autran, D1
Barrie, M1
Matta, M1
Monserrat, C1
Campello, C1
Petrirena, G1
Boucard, C1
Padovani, L1
Loundou, A1
Appay, R1
Graillon, T1
Dufour, H1
Figarella-Branger, D1
Chinot, O1
Tabouret, E1
Huang, HC1
Cheng, AL1
Lin, CW1
Kuo, SH1
Yoshida, T2
Ushio, Y3
Hayakawa, T2
Shimizu, K2
Mogami, H2
Nakata, Y2
Sakamoto, Y2
Robustelli della Cuna, G1
Paoletti, P1
Bernardo, G1
Knerich, R1
Butti, G1
Cuzzoni, Q1
Vincent, FM1
Jackson, H1
Jackson, NC1
Bock, M1
Lendon, M1
Nemoto, S1
Kitamura, I1
Kochi, M1
Matsumoto, Y1
Ueoka, R1
Kuratsu, J1
Humphrey, GB1
Krous, HF1
Filler, J1
Maxwell, JD1
VanHoutte, JJ1
Freund, M1
Ostendorf, P1
Waller, HD1
Kornblith, PL1
Szypko, PE1
Sayas, MJ1
Sanz, MA1
Martín-Aragonés, G1
Javier Rafecas, F1
Martínez, JA1
Lorenzo, IJ1
Sanz, GF1
Gomis, F1
Marty, ML1
Donadio, D1
Navarro, M1
Izarn, P1
Constine, LS1
Rubin, P1
Woolf, PD1
Doane, K1
Lush, CM1
Sullivan, MP1
Boyett, J1
Pullen, J1
Crist, W1
Doering, EJ1
Trueworthy, R1
Hvizdala, E1
Ruymann, F1
Steuber, CP1
Panasci, LC1
Dufour, M1
Chevalier, L1
Isabel, G1
Lazarus, P1
McQuillan, A1
Arbit, E1
Brem, S1
Feindel, W1

Reviews

1 review available for carmustine and Meningeal Neoplasms

ArticleYear
Treatment of overt CNS leukemia.
    The American journal of pediatric hematology/oncology, 1979,Spring, Volume: 1, Issue:1

    Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Blood-Brain Barrier; Carm

1979

Trials

1 trial available for carmustine and Meningeal Neoplasms

ArticleYear
Pediatric Oncology Group experience with modified LSA2-L2 therapy in 107 children with non-Hodgkin's lymphoma (Burkitt's lymphoma excluded).
    Cancer, 1985, Jan-15, Volume: 55, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Marrow; Carmustine; Child; Child, Preschool; C

1985

Other Studies

15 other studies available for carmustine and Meningeal Neoplasms

ArticleYear
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab.
    Annals of hematology, 2013, Volume: 92, Issue:7

    Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Carmu

2013
[Chemotherapy of experimental meningeal gliomatosis].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Carmustine; Glioma; Male;

1984
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
    Neurosurgery, 1982, Volume: 11, Issue:3

    Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma;

1982
Spinal leptomeningeal invasion from intracranial glioblastoma multiforme.
    Archives of physical medicine and rehabilitation, 1983, Volume: 64, Issue:1

    Topics: Brain Neoplasms; Carmustine; Cauda Equina; Cerebrospinal Fluid; Child, Preschool; Cobalt Radioisotop

1983
Testicular invasion and relapse and meningeal involvement in a rat T-cell leukaemia.
    British journal of cancer, 1984, Volume: 50, Issue:5

    Topics: Animals; Carmustine; Disease Models, Animal; Female; Leukemia, Lymphoid; Male; Meningeal Neoplasms;

1984
[Meningeal gliomatosis models as a chemosensitivity assay system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Disease Models, Animal; Dr

1984
[Intravascular surgery for brain tumors].
    No to shinkei = Brain and nerve, 1993, Volume: 45, Issue:5

    Topics: Brain Neoplasms; Carmustine; Chemoembolization, Therapeutic; Humans; Meningeal Neoplasms; Meningioma

1993
Intrathecal chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea encapsulated into hybrid liposomes for meningeal gliomatosis: an experimental study.
    Cancer research, 1996, Sep-01, Volume: 56, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dogs; Drug Carriers; Glioma;

1996
[(Meningeal carcinomatosis in patients with breast cancer)].
    Onkologie, 1979, Volume: 2, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Carmustine; Female; Humans; Injections, Spinal; Mastectomy; Meningeal

1979
Variations in response of human brain tumors to BCNU in vitro.
    Journal of neurosurgery, 1978, Volume: 48, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cells, Cultured; Glioma; Humans; Meningeal Neoplasms; Meningioma

1978
[Treatment of acute adult myeloblastic leukemia with intensive chemotherapy].
    Sangre, 1986, Volume: 31, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Thera

1986
[Neuromeningeal localizations in acute leukemia and non-Hodgkin's lymphoma. Protocol combining BCNU-cytosine arabinoside].
    Annales de medecine interne, 1987, Volume: 138, Issue:2

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cytarabi

1987
Hyperprolactinemia and hypothyroidism following cytotoxic therapy for central nervous system malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Child; Child, Preschool;

1987
Utilization of the HTSCA and CFU-C assay to identify two new 2-chloroethylnitrosourea congeners of amino acid amides with increased in vitro activity against human glioma compared with BCNU.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Colony-Forming Units Assay; Glioma; Humans; In Vitro

1985