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carmustine and Lung Diseases, Interstitial

carmustine has been researched along with Lung Diseases, Interstitial in 4 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Lung Diseases, Interstitial: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Research Excerpts

ExcerptRelevanceReference
"A decreased incidence of interstitial pneumonitis as well as a possible benefit in efficacy has been reported with lomustine (CCNU) compared to BCNU in the standard dose setting."2.70Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease. ( Blume, KG; Chao, NS; Horning, SJ; Johnston, LJ; Long, GD; Negrin, RS; Shizuru, JA; Stockerl-Goldstein, KE; Stuart, MJ; Wong, RM, 2001)
"We report a fatal case of acute interstitial pneumonitis in a patient treated with carmustine (BCNU) for a brain tumor."1.29Severe diffuse interstitial pneumonitis induced by carmustine (BCNU). ( Delaval, P; Desrues, B; Le Coz, A; Lena, H; Quinquenel, ML, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chastagner, P1
Kalifa, C1
Doz, F1
Bouffet, E1
Gentet, JC1
Ruchoux, MM1
Bracard, S1
Desandes, E1
Frappaz, D1
Klingemann, HG1
Shepherd, JD1
Reece, DE1
Barnett, MJ1
Nantel, SH1
Sutherland, HJ1
Spinelli, JJ1
Phillips, GL1
Lena, H1
Desrues, B1
Le Coz, A1
Quinquenel, ML1
Delaval, P1
Stuart, MJ1
Chao, NS1
Horning, SJ1
Wong, RM1
Negrin, RS1
Johnston, LJ1
Shizuru, JA1
Long, GD1
Blume, KG1
Stockerl-Goldstein, KE1

Reviews

1 review available for carmustine and Lung Diseases, Interstitial

ArticleYear
Regimen-related acute toxicities: pathophysiology, risk factors, clinical evaluation and preventive strategies.
    Bone marrow transplantation, 1994, Volume: 14 Suppl 4

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Tr

1994

Trials

2 trials available for carmustine and Lung Diseases, Interstitial

ArticleYear
Outcome of children treated with preradiation chemotherapy for a high-grade glioma: results of a French Society of Pediatric Oncology (SFOP) Pilot Study.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvan

2007
Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2001, Volume: 7, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2001

Other Studies

1 other study available for carmustine and Lung Diseases, Interstitial

ArticleYear
Severe diffuse interstitial pneumonitis induced by carmustine (BCNU).
    Chest, 1994, Volume: 105, Issue:5

    Topics: Acute Disease; Adult; Brain Neoplasms; Carmustine; Fatal Outcome; Humans; Lung Diseases, Interstitia

1994