carmustine has been researched along with Liver Neoplasms in 54 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conducted a phase I trial of high dose paracetamol and carmustine (BCNU) in patients with advanced malignant melanoma to determine the optimal biological dose and the maximum tolerated dose (MTD) with the goal of increasing sensitivity to BCNU by GSH depletion." | 9.10 | Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma. ( Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD, 2003) |
| "This study was designed to determine if hepatic arterial therapy with floxuridine (F), mitomycin, and carmustine (BCNU) (FMB) is superior to hepatic arterial therapy with F alone in previously treated patients with hepatic metastases from colorectal cancer." | 9.07 | Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer. ( Botet, J; Budd, A; Cohen, A; Conti, JA; Kemeny, N; Niedzwiecki, D; Seiter, K; Sigurdson, ER; Tao, Y, 1993) |
| "Seventy-five previously untreated patients with measurable advanced colorectal cancer were treated with 5 fluorouracil 1,000 mg/m2 as a 24-hour intravenous (i." | 8.78 | 120-hour 5-fluorouracil (5-FU) continuous infusion (CI) plus BCNU in advanced colorectal cancer. ( Aguilo, J; Asencio, F; Candel, MT; Delgado, F; García-Reinoso, J; Martínez-Abad, M; Sánchez, JJ; Sanchis, C; Viciano, V; Villar-Grimalt, A, 1991) |
| " In both HepG2 and J5 HCC cell lines, a synergistic antiproliferative effect was observed when a low dosage of BP was combined with the chemotherapeutic drug 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)." | 5.36 | Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth. ( Chan, DC; Chen, YL; Harn, HJ; Jian, MH; Lin, CC; Lin, PC; Lin, SZ; Su, CC; Su, KJ; Tseng, IH; Wei, CW; Yu, SL; Yu, YL, 2010) |
| " We conducted a phase I trial of high dose paracetamol and carmustine (BCNU) in patients with advanced malignant melanoma to determine the optimal biological dose and the maximum tolerated dose (MTD) with the goal of increasing sensitivity to BCNU by GSH depletion." | 5.10 | Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma. ( Chang, C; Chapman, PB; Fleisher, M; Hwu, WJ; Krown, SE; Livingston, PO; Pinto, JT; Williams, L; Wolchok, JD, 2003) |
| "This study was designed to determine if hepatic arterial therapy with floxuridine (F), mitomycin, and carmustine (BCNU) (FMB) is superior to hepatic arterial therapy with F alone in previously treated patients with hepatic metastases from colorectal cancer." | 5.07 | Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer. ( Botet, J; Budd, A; Cohen, A; Conti, JA; Kemeny, N; Niedzwiecki, D; Seiter, K; Sigurdson, ER; Tao, Y, 1993) |
| "Seventy-five previously untreated patients with measurable advanced colorectal cancer were treated with 5 fluorouracil 1,000 mg/m2 as a 24-hour intravenous (i." | 4.78 | 120-hour 5-fluorouracil (5-FU) continuous infusion (CI) plus BCNU in advanced colorectal cancer. ( Aguilo, J; Asencio, F; Candel, MT; Delgado, F; García-Reinoso, J; Martínez-Abad, M; Sánchez, JJ; Sanchis, C; Viciano, V; Villar-Grimalt, A, 1991) |
| "BCNU, hydroxyurea, and imidazole carboxamide (DTIC) were administered to 89 patients with disseminated malignant melanoma." | 3.65 | Combination chemotherapy for disseminated malignant melanoma. ( Coltman, CA; Costanzi, JJ; Delaney, FC; Hoogstraten, B; Quagliana, JM; Vaitkevicius, VK, 1975) |
| "Uveal melanoma is the most common primary intraocular malignancy in adults and the liver is the most common site for systemic metastases." | 2.71 | Chemoembolization of the hepatic artery with BCNU for metastatic uveal melanoma: results of a phase II study. ( Berd, D; Mastrangelo, MJ; Patel, K; Sato, T; Shields, CL; Shields, JA; Sullivan, K, 2005) |
| " In both HepG2 and J5 HCC cell lines, a synergistic antiproliferative effect was observed when a low dosage of BP was combined with the chemotherapeutic drug 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)." | 1.36 | Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth. ( Chan, DC; Chen, YL; Harn, HJ; Jian, MH; Lin, CC; Lin, PC; Lin, SZ; Su, CC; Su, KJ; Tseng, IH; Wei, CW; Yu, SL; Yu, YL, 2010) |
| "We present a patient with metastatic breast cancer treated with high-dose chemotherapy and bone marrow transplantation." | 1.29 | Clostridium septicum abscess in hepatic metastases: successful medical management. ( Ciaccia, D; Corey, GR; Peters, W; Thel, MC; Vredenburgh, JJ, 1994) |
| "on post-surgical spontaneous metastases of a non-immunogenic tumour." | 1.28 | Postsurgical adjuvant chemoimmunotherapy with recombinant interleukin-2 and 1,3-bis-(2-chloroethyl)-1-nitrosourea on spontaneous metastases of a non-immunogenic murine tumour. ( Acerbis, G; Cleris, L; Formelli, F; Parmiani, G; Rodolfo, M, 1992) |
| "Treatment of rat hepatoma cells (H4 cells) with various DNA-damaging agents increases the number of O6-methylguanine-DNA-methyltransferase (transferase) molecules per cell." | 1.28 | Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea resistance by gamma-irradiation or drug pretreatment in rat hepatoma cells. ( Habraken, Y; Laval, F, 1991) |
| "The mitomycin C and BCNU were alternated monthly at the start of each FUDR cycle." | 1.27 | Treatment of metastatic colorectal cancer with hepatic artery combination chemotherapy. ( Cohen, AM; Higgins, J; Schaeffer, N, 1986) |
| "In nine of 11 (82%) instances, tumors were sensitive to a particular drug, and the patient had at least 50% regression of tumor following treatment with the tested drug." | 1.26 | Clinical correlations with drug sensitivities in the clonogenic assay: a retrospective study. ( Burk, MW; Campbell, MA; Giuliano, AE; Kaiser, LR; Kern, DH; Mann, BD; Morton, DL, 1982) |
| "A case of hepatocellular carcinoma in a young female is presented in which the apparent etiology was the use of oral contraceptives for 5 1/2 years." | 1.26 | Hepatocellular carcinoma in a young woman with prolonged exposure to oral contraceptives. ( Gattanell, PN; Holland, JF; Perloff, M, 1978) |
| "Skin, lymph node, and soft tissue metastases more frequently responded to therapy, while hepatic, peritoneal, and osseous metastases responded with an intermediate frequency." | 1.26 | Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC 409962) and cyclophosphamide therapy of drug-resistant metastatic breast carcinoma. ( Klahr, C; Presant, CA; Van Amburg, A, 1977) |
| "Although advanced gastrointestinal cancer is the most commonplace problem encountered by the medical oncologist, this group of diseases has proved exceedingly resistant to past chemotherapy efforts." | 1.25 | Clinical management of advanced gastrointestinal cancer. ( Moertel, CG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (64.81) | 18.7374 |
| 1990's | 11 (20.37) | 18.2507 |
| 2000's | 6 (11.11) | 29.6817 |
| 2010's | 2 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gonsalves, CF | 1 |
| Eschelman, DJ | 1 |
| Thornburg, B | 1 |
| Frangos, A | 1 |
| Sato, T | 2 |
| Yu, YL | 1 |
| Yu, SL | 1 |
| Su, KJ | 1 |
| Wei, CW | 1 |
| Jian, MH | 1 |
| Lin, PC | 1 |
| Tseng, IH | 1 |
| Lin, CC | 1 |
| Su, CC | 1 |
| Chan, DC | 1 |
| Lin, SZ | 1 |
| Harn, HJ | 1 |
| Chen, YL | 1 |
| Janciauskiene, R | 1 |
| Juozaityte, E | 1 |
| Pavalkis, D | 1 |
| Wolchok, JD | 1 |
| Williams, L | 1 |
| Pinto, JT | 1 |
| Fleisher, M | 1 |
| Krown, SE | 1 |
| Hwu, WJ | 1 |
| Livingston, PO | 1 |
| Chang, C | 1 |
| Chapman, PB | 1 |
| Hung, H | 1 |
| Pierce, CK | 1 |
| Chee, SK | 1 |
| Lawrence, P | 1 |
| Hung, NT | 1 |
| Patel, K | 1 |
| Sullivan, K | 1 |
| Berd, D | 1 |
| Mastrangelo, MJ | 1 |
| Shields, CL | 1 |
| Shields, JA | 1 |
| Schmitz, R | 3 |
| Krakamp, B | 3 |
| Troidl, H | 1 |
| Li, RH | 1 |
| Tam, WH | 1 |
| Ng, PC | 1 |
| Mok, TS | 1 |
| Tam, B | 1 |
| Lau, TK | 1 |
| Mann, BD | 1 |
| Kern, DH | 1 |
| Giuliano, AE | 1 |
| Burk, MW | 1 |
| Campbell, MA | 1 |
| Kaiser, LR | 1 |
| Morton, DL | 1 |
| Cohen, AM | 3 |
| Kaufman, SD | 2 |
| Wood, WC | 2 |
| Greenfield, AJ | 1 |
| Hinterberger, R | 1 |
| Fischer, J | 1 |
| Preiss, J | 1 |
| Weigand, H | 1 |
| Hanna, MG | 1 |
| Key, ME | 1 |
| Queisser, W | 1 |
| Schnitzler, G | 1 |
| Heim, ME | 1 |
| König, H | 1 |
| Katz, R | 1 |
| Fritze, D | 1 |
| Herrmann, R | 1 |
| Arnold, H | 1 |
| Henss, H | 1 |
| Trux, F | 1 |
| Dakhil, S | 1 |
| Ensminger, W | 1 |
| Cho, K | 1 |
| Niederhuber, J | 1 |
| Doan, K | 1 |
| Wheeler, R | 1 |
| Thel, MC | 1 |
| Ciaccia, D | 1 |
| Vredenburgh, JJ | 1 |
| Peters, W | 1 |
| Corey, GR | 1 |
| Saez, RA | 1 |
| Slease, RB | 1 |
| Selby, GB | 1 |
| Strnad, C | 1 |
| Epstein, RB | 1 |
| Confer, DL | 1 |
| Zhang, YP | 1 |
| He, T | 1 |
| Chen, JM | 1 |
| Chen, YN | 1 |
| Xu, HY | 1 |
| Fan, GC | 1 |
| Wu, Y | 1 |
| Kemeny, N | 1 |
| Cohen, A | 1 |
| Seiter, K | 1 |
| Conti, JA | 1 |
| Sigurdson, ER | 1 |
| Tao, Y | 1 |
| Niedzwiecki, D | 1 |
| Botet, J | 1 |
| Budd, A | 1 |
| Stark, JJ | 1 |
| Dillman, RO | 1 |
| Schulof, R | 1 |
| Wiemann, MC | 1 |
| Barth, NM | 1 |
| Honeycutt, PJ | 1 |
| Soori, G | 1 |
| Fiorillo, A | 1 |
| Maggi, G | 1 |
| Martone, A | 1 |
| Migliorati, R | 1 |
| D'Amore, R | 1 |
| Alfieri, E | 1 |
| Greco, N | 1 |
| Cirillo, S | 1 |
| Marano, I | 1 |
| McIntire, KR | 1 |
| Vogel, CL | 1 |
| Primack, A | 1 |
| Waldmann, TA | 1 |
| Kyalwazi, SK | 1 |
| Pettavel, J | 1 |
| Morgenthaler, FR | 1 |
| Baril, BB | 1 |
| Baril, EF | 1 |
| Laszlo, J | 2 |
| Wheeler, GP | 1 |
| Moertel, CG | 3 |
| Bast, RC | 1 |
| Segerling, M | 1 |
| Ohanian, SH | 1 |
| Greene, SL | 1 |
| Zbar, B | 1 |
| Rapp, HJ | 1 |
| Borsos, T | 1 |
| Miyahara, M | 2 |
| Nakadate, M | 1 |
| Suzuki, I | 1 |
| Ishidate, M | 1 |
| Odashima, S | 1 |
| Gattanell, PN | 1 |
| Perloff, M | 1 |
| Holland, JF | 1 |
| Senzer, NN | 1 |
| Terrell, W | 1 |
| Pratt, CB | 1 |
| Ensminger, WD | 1 |
| Thompson, M | 1 |
| Come, S | 1 |
| Egan, EM | 1 |
| Presant, CA | 1 |
| Van Amburg, A | 1 |
| Klahr, C | 1 |
| Costanzi, JJ | 1 |
| Vaitkevicius, VK | 1 |
| Quagliana, JM | 1 |
| Hoogstraten, B | 2 |
| Coltman, CA | 1 |
| Delaney, FC | 2 |
| Van Dyk, JJ | 1 |
| Falkson, G | 1 |
| Chen, J | 1 |
| Zhang, Y | 1 |
| Sui, J | 1 |
| Chen, Y | 1 |
| Acerbis, G | 1 |
| Cleris, L | 1 |
| Rodolfo, M | 1 |
| Parmiani, G | 1 |
| Formelli, F | 1 |
| Habraken, Y | 1 |
| Laval, F | 1 |
| Villar-Grimalt, A | 1 |
| Candel, MT | 1 |
| Delgado, F | 1 |
| García-Reinoso, J | 1 |
| Sanchis, C | 1 |
| Viciano, V | 1 |
| Asencio, F | 1 |
| Martínez-Abad, M | 1 |
| Aguilo, J | 1 |
| Sánchez, JJ | 1 |
| Knöpfle, G | 1 |
| Leidig, P | 1 |
| Ayash, LJ | 1 |
| Hunt, M | 1 |
| Antman, K | 1 |
| Nadler, L | 1 |
| Wheeler, C | 1 |
| Takvorian, T | 1 |
| Elias, A | 2 |
| Antin, JH | 1 |
| Greenough, T | 1 |
| Eder, JP | 2 |
| Mennigen, R | 1 |
| Barkun, J | 1 |
| Klauke, H | 1 |
| Ficorella, C | 1 |
| Cagnazzo, P | 1 |
| Cardi, G | 1 |
| Ricciuti, FP | 1 |
| Marchetti, P | 1 |
| Frati, L | 1 |
| Marchei, P | 1 |
| Schaeffer, N | 1 |
| Higgins, J | 1 |
| Shea, TC | 1 |
| Antman, KH | 1 |
| Peters, WP | 1 |
| Schryber, S | 1 |
| Henner, WD | 1 |
| Schoenfeld, DA | 1 |
| Schnipper, LE | 1 |
| Frei, E | 2 |
| De Lisi, V | 1 |
| Cocconi, G | 1 |
| Tonato, M | 1 |
| Di Costanzo, F | 1 |
| Leonardi, F | 1 |
| Soldani, M | 1 |
| Eisenbrand, G | 1 |
| Müller, N | 1 |
| Denkel, E | 1 |
| Sterzel, W | 1 |
| Inaba, M | 1 |
| Sakurai, Y | 1 |
| Baril, E | 1 |
| Baril, B | 1 |
| Scott, MT | 1 |
| Lewis, MB | 1 |
| Nunes, LB | 1 |
| Powell, DE | 1 |
| Shnider, BI | 1 |
| Omura, GA | 1 |
| Roberts, GA | 1 |
| Gottlieb, JA | 2 |
| Rivkin, SE | 1 |
| Spigel, SC | 1 |
| O'Bryan, RM | 1 |
| Singhakowinta, A | 1 |
| Einhorn, LH | 1 |
| Burgess, MA | 1 |
| Vallejos, C | 1 |
| Bodey, GP | 1 |
| Gutterman, J | 1 |
| Mavligit, G | 1 |
| Hersh, EM | 1 |
| Luce, JK | 1 |
| Freireich, EJ | 1 |
4 reviews available for carmustine and Liver Neoplasms
| Article | Year |
|---|---|
[The role of the regional (intra-arterial) chemotherapy in the treatment of hepatic metastases of colorectal cancer].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 2003 |
120-hour 5-fluorouracil (5-FU) continuous infusion (CI) plus BCNU in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Colorectal Neopl | 1991 |
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds.
Topics: Alkylation; Animals; Antineoplastic Agents; Carcinogens; Carmustine; Chemical Phenomena; Chemistry; | 1986 |
Corynebacterium parvum as an immunotherapeutic anticancer agent.
Topics: Animals; Carmustine; Corynebacterium; Humans; Immunity; Immunity, Cellular; Immunotherapy; Lectins; | 1974 |
8 trials available for carmustine and Liver Neoplasms
| Article | Year |
|---|---|
Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Carmusti | 2003 |
Chemoembolization of the hepatic artery with BCNU for metastatic uveal melanoma: results of a phase II study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Carmustine; Chemoembolization, Th | 2005 |
[Prospective randomized study in advanced stomach cancer. Comparison between combinations of 5-fluorouracil and carmustine without and with adriamycin].
Topics: Adult; Aged; Carmustine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukocyte Cou | 1984 |
Long-term survival after autologous bone marrow transplantation for metastatic breast carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; | 1995 |
Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorect | 1993 |
Interferon-alpha and chemohormonal therapy for patients with advanced melanoma: final results of a phase I-II study of the Cancer Biotherapy Research Group and the Mid-Atlantic Oncology Program.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modality Therapy; Da | 1998 |
Value of in vivo tissue testing in predicting the clinical response to regional perfusion chemotherapy in colorectal cancer patients with liver metastases.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorect | 1989 |
Randomized comparison of 5-FU alone or combined with carmustine, doxorubicin, and mitomycin (BAFMi) in the treatment of advanced gastric cancer: a phase III trial of the Italian Clinical Research Oncology Group (GOIRC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; D | 1986 |
42 other studies available for carmustine and Liver Neoplasms
| Article | Year |
|---|---|
Uveal Melanoma Metastatic to the Liver: Chemoembolization With 1,3-Bis-(2-Chloroethyl)-1-Nitrosourea.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Carmustine; Chemoembolization, Th | 2015 |
Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth.
Topics: Angelica sinensis; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Cell Line, Tumor; C | 2010 |
SarCNU-induced G2/M arrest in hepatoma cells is mediated by a p53-independent phosphorylation of cdc-2 at Tyr15.
Topics: Carmustine; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-D | 2005 |
Perfusion chemotherapy for colorectal liver metastases: a randomized study comparing FUDR against 5-FU/BCNU.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorectal Neoplasms; Floxuridine; Fluor | 1989 |
Microphthalmos associated with Dartmouth combination chemotherapy in pregnancy: a case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Dacarbazine; Female; H | 2007 |
Clinical correlations with drug sensitivities in the clonogenic assay: a retrospective study.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Hepatocellular; Carmustine; Cell Division; D | 1982 |
Regional hepatic chemotherapy using an implantable drug infusion pump.
Topics: Antineoplastic Agents; Carmustine; Drug Therapy, Combination; Floxuridine; Hepatic Artery; Humans; I | 1983 |
Intrahepatic chemotherapy in isolated liver metastases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Dacarbazine; Female; Floxuridine; Fluoro | 1983 |
Immunotherapy of metastases enhances subsequent chemotherapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; BCG Vaccine; Carcinoma, Hepatocellular; Carmusti | 1982 |
Improved regional selectivity of hepatic arterial BCNU with degradable microspheres.
Topics: Carmustine; Embolization, Therapeutic; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver; Li | 1982 |
Clostridium septicum abscess in hepatic metastases: successful medical management.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1994 |
[Specific curative effects of nitrosourea drugs on tumor cells with Mer--phenotype in Chinese].
Topics: Animals; Carmustine; Female; Humans; Liver Neoplasms; Methyltransferases; Mice; Mice, Inbred BALB C; | 1993 |
Shunt-related abdominal metastases in an infant with medulloblastoma: long-term remission by systemic chemotherapy and surgery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carmustine; Cerebellar Neoplasms; Combi | 2001 |
Effect of surgical and chemotherapeutic treatment on alpha-fetoprotein levels in patients with hepatocellular carcinoma.
Topics: alpha-Fetoproteins; Carmustine; Fetal Proteins; Humans; Liver Neoplasms; Methotrexate; Recurrence | 1976 |
[Treatment of primary and secondary liver tumors using a combination of chemotherapy and surgery].
Topics: Antineoplastic Agents; Carmustine; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Leu | 1975 |
Inhibition of rat liver DNA polymerase by nitrosoureas and isocyanates.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Cyanates; Cyclohexanes; Cyclo | 1975 |
Clinical management of advanced gastrointestinal cancer.
Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Ther | 1975 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Do | 1976 |
Walter Hubert lecture Chemotherapy of upper gastrointestinal carcinoma.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, S | 1976 |
Antitumor effect of 1,1'-polymethylene-bis (1-nitrosourea) and related compounds.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Drug Evaluation, Preclinical; | 1977 |
Hepatocellular carcinoma in a young woman with prolonged exposure to oral contraceptives.
Topics: Adult; Carcinoma, Hepatocellular; Carmustine; Contraceptives, Oral; Contraceptives, Oral, Combined; | 1978 |
Evaluation of a chemotherapeutic regimen for primary liver cancer in children.
Topics: Adolescent; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Child; Doxorubicin; Drug E | 1978 |
Hepatic arterial BCNU: a pilot clinical-pharmacologic study in patients with liver tumors.
Topics: Carmustine; Female; Hepatic Artery; Hepatic Veins; Humans; Infusions, Intra-Arterial; Liver Neoplasm | 1978 |
Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC 409962) and cyclophosphamide therapy of drug-resistant metastatic breast carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Agranulocytosis; Ascites; Bone Neoplasms; Breast Neoplasms; Carmustine; | 1977 |
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neo | 1976 |
Combination chemotherapy for disseminated malignant melanoma.
Topics: Adolescent; Adult; Aged; Amides; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Therapy, C | 1975 |
A clinical trial of procarbazine plus vincristine plus bis-chloroethyl-nitrosourea plus imidazole carboxamide dimethyl triazeno in metastatic malignant melanoma.
Topics: Adult; Aged; Carmustine; Dacarbazine; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lu | 1975 |
O6-methylguanine-DNA methyltransferase activity and sensitivity of human tumor cell lines to bis-chloroethylnitrosourea.
Topics: Carcinoma, Hepatocellular; Carmustine; Drug Resistance; Drug Synergism; Female; Humans; Liver Neopla | 1992 |
Postsurgical adjuvant chemoimmunotherapy with recombinant interleukin-2 and 1,3-bis-(2-chloroethyl)-1-nitrosourea on spontaneous metastases of a non-immunogenic murine tumour.
Topics: Animals; Carmustine; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administratio | 1992 |
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea resistance by gamma-irradiation or drug pretreatment in rat hepatoma cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Cisplatin; Combined Modality | 1991 |
[Primary and metastatic liver tumors--evaluation of tumor regression and response with regional cytostatic drug therapy by sonography and fine needle puncture histology].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Hepatocellular; Carmustin | 1990 |
Hepatic venoocclusive disease in autologous bone marrow transplantation of solid tumors and lymphomas.
Topics: Adult; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Female; Hepatic Veno-Occl | 1990 |
[Rationale and current results of loco-regional chemotherapy in hepatic metastases of colorectal carcinoma].
Topics: Antineoplastic Agents; Carmustine; Cisplatin; Colorectal Neoplasms; Doxorubicin; Floxuridine; Fluoro | 1987 |
Treatment of metastatic colorectal cancer with hepatic artery combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Fluorouracil; Follow- | 1986 |
Treatment of colorectal cancer hepatic metastases by hepatic artery chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Floxuridine; Fluorour | 1985 |
Malignant melanoma. Treatment with high-dose combination alkylating agent chemotherapy and autologous bone marrow support.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Cisp | 1988 |
Combined effect of nitrogen mustard and DNA repair inhibitor on the resistant tumor.
Topics: Animals; Carcinoma, Hepatocellular; Carmustine; Cell Line; Cyanates; DNA Repair; Drug Resistance; Dr | 1974 |
DNA polymerases in normal and regenerating rat liver and hepatomas: targets for chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Cell Fractionation; Cyanates; | 1974 |
Extra-axial spread of medulloblastoma.
Topics: Autopsy; Brain Neoplasms; Carmustine; Cranial Fossa, Posterior; Femoral Neoplasms; Humans; Liver Neo | 1973 |
Combination therapy of solid tumors using 1,3-bis(2-chloroethyl)-1-nitrosourea (NCNU), vincristine, methotrexate, and 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Carmustine; Female; Fluorouracil; Gastrointes | 1973 |
Proceedings: Superiority of adriamycin over oral nitrosoureas in patients with advanced breast carcinoma. A Southwest Cancer Chemotherapy study Group study.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Carmustine; Cyclohexanes; Doxorubicin; Female; Humans | 1974 |
Prognostic correlations and response to treatment in advanced metastatic malignant melanoma.
Topics: Adolescent; Adult; Aged; Amides; Antineoplastic Agents; Brain; Brain Neoplasms; Carmustine; Dexameth | 1974 |