carmustine has been researched along with Injuries, Radiation in 20 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Conventional treatment of glioblastoma multiforme (GBM) cures less than 5% of patients." | 6.71 | Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. ( Brachman, D; Buckner, J; Curran, WJ; Lustig, R; Mehta, MP; Okunieff, P; Podgorsak, EB; Sause, W; Schultz, CJ; Seiferheld, W; Souhami, L; Werner-Wasik, M; Zamorano, L, 2004) |
| "The outcome after treatment for glioblastoma remains poor." | 6.69 | Carboplatin and teniposide concurrent with radiotherapy in patients with glioblastoma multiforme: a phase II study. ( Altavilla, G; Brandes, AA; Carollo, C; Chierichetti, F; Ermani, M; Florentino, MV; Rigon, A; Turazzi, S; Zampieri, P, 1998) |
| "A retrospective study of 30 cases of Hodgkin disease in patients who underwent high-dose carmustine, etoposide, and cyclophosphamide chemotherapy with PBSC support was performed." | 3.70 | Hematologic toxic reaction to radiation therapy adjuvant to autologous peripheral blood stem cell transplantation for recurrent or refractory Hodgkin disease. ( Bogart, JA; Chung, CT; Ryu, S; Ungureanu, C; Zamkoff, KW, 2000) |
| "Conventional treatment of glioblastoma multiforme (GBM) cures less than 5% of patients." | 2.71 | Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. ( Brachman, D; Buckner, J; Curran, WJ; Lustig, R; Mehta, MP; Okunieff, P; Podgorsak, EB; Sause, W; Schultz, CJ; Seiferheld, W; Souhami, L; Werner-Wasik, M; Zamorano, L, 2004) |
| "The outcome after treatment for glioblastoma remains poor." | 2.69 | Carboplatin and teniposide concurrent with radiotherapy in patients with glioblastoma multiforme: a phase II study. ( Altavilla, G; Brandes, AA; Carollo, C; Chierichetti, F; Ermani, M; Florentino, MV; Rigon, A; Turazzi, S; Zampieri, P, 1998) |
| "No fatal complications or chronic pulmonary fibrosis was seen." | 2.68 | Pulmonary toxicity of high-dose chemotherapy for breast cancer: a non-invasive approach to diagnosis and treatment. ( Chap, L; Glaspy, J; Levine, M; Lill, M; Norton, L; Shpiner, R, 1997) |
| "Radiation necrosis impacts the quality of life in cancer survivors, and it is essential to detect and effectively treat this entity as early as possible." | 2.49 | Cerebral radiation necrosis: a review of the pathobiology, diagnosis and management considerations. ( Marko, NF; Rahmathulla, G; Weil, RJ, 2013) |
| "A 12 1/2-year-old female presented with Ewing's sarcoma of the manubrium sterni which extended into the anterior mediastinum." | 1.26 | Primary Ewing's sarcoma of the sternum: a case report. ( Freeman, AI; Ghoorah, J; Kedar, A; Mindell, ER; Tebbi, CK; Thomas, PR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Köksal, M | 1 |
| Kersting, L | 1 |
| Schoroth, F | 1 |
| Garbe, S | 1 |
| Koch, D | 1 |
| Scafa, D | 1 |
| Sarria, GR | 1 |
| Leitzen, C | 1 |
| Heine, A | 1 |
| Holderried, T | 1 |
| Brossart, P | 1 |
| Zoga, E | 1 |
| Attenberger, U | 1 |
| Schmeel, LC | 1 |
| Rahmathulla, G | 1 |
| Marko, NF | 1 |
| Weil, RJ | 1 |
| Dawson, LA | 1 |
| Saito, NG | 1 |
| Ratanatharathorn, V | 1 |
| Uberti, JP | 1 |
| Adams, PT | 1 |
| Ayash, LJ | 1 |
| Reynolds, CM | 1 |
| Silver, SM | 1 |
| Schipper, MJ | 1 |
| Lichter, AS | 1 |
| Eisbruch, A | 1 |
| Souhami, L | 1 |
| Seiferheld, W | 1 |
| Brachman, D | 1 |
| Podgorsak, EB | 1 |
| Werner-Wasik, M | 1 |
| Lustig, R | 1 |
| Schultz, CJ | 1 |
| Sause, W | 1 |
| Okunieff, P | 1 |
| Buckner, J | 1 |
| Zamorano, L | 2 |
| Mehta, MP | 1 |
| Curran, WJ | 1 |
| Vordermark, D | 1 |
| Kölbl, O | 1 |
| Collis, CH | 1 |
| Dietz, R | 1 |
| Burger, L | 1 |
| Schimrigk, K | 1 |
| Merkel, KH | 1 |
| Sklar, CA | 1 |
| Kim, TH | 1 |
| Ramsay, NK | 1 |
| Domenech, J | 1 |
| Linassier, C | 1 |
| Gihana, E | 1 |
| Dayan, A | 1 |
| Truglio, D | 1 |
| Bout, M | 1 |
| Petitdidier, C | 1 |
| Delain, M | 1 |
| Petit, A | 1 |
| Brémond, JL | 1 |
| Fernández-Hidalgo, OA | 1 |
| Vanaclocha, V | 1 |
| Vieitez, JM | 1 |
| Aristu, JJ | 1 |
| Rebollo, J | 1 |
| Gúrpide, A | 1 |
| Aramendía, JM | 1 |
| Moreno-Palanques, R | 1 |
| Martín-Algarra, S | 1 |
| Subirá, ML | 1 |
| Brugarolas, A | 1 |
| Brandes, AA | 1 |
| Rigon, A | 1 |
| Zampieri, P | 1 |
| Ermani, M | 1 |
| Carollo, C | 1 |
| Altavilla, G | 1 |
| Turazzi, S | 1 |
| Chierichetti, F | 1 |
| Florentino, MV | 1 |
| Chap, L | 1 |
| Shpiner, R | 1 |
| Levine, M | 1 |
| Norton, L | 1 |
| Lill, M | 1 |
| Glaspy, J | 1 |
| Bogart, JA | 1 |
| Ungureanu, C | 1 |
| Ryu, S | 1 |
| Chung, CT | 1 |
| Zamkoff, KW | 1 |
| Alvarnas, JC | 1 |
| Negrin, RS | 1 |
| Horning, SJ | 1 |
| Hu, WW | 1 |
| Long, GD | 1 |
| Schriber, JR | 1 |
| Stockerl-Goldstein, K | 1 |
| Tierney, K | 1 |
| Wong, R | 1 |
| Blume, KG | 1 |
| Chao, NJ | 1 |
| Phillips, TL | 1 |
| Wharam, MD | 1 |
| Margolis, LW | 1 |
| Kedar, A | 1 |
| Ghoorah, J | 1 |
| Thomas, PR | 1 |
| Mindell, ER | 1 |
| Tebbi, CK | 1 |
| Freeman, AI | 1 |
| Mahaley, MS | 1 |
| Vogel, FS | 1 |
| Burger, P | 1 |
| Ghatak, NR | 1 |
| Tonn, JC | 1 |
| Roosen, K | 1 |
| Schachenmayr, W | 1 |
| Katanick, D | 1 |
| Dujovny, M | 1 |
| Yakar, D | 1 |
| Malik, G | 1 |
| Ausman, JI | 1 |
| Di Chiro, G | 1 |
| Oldfield, E | 1 |
| Wright, DC | 1 |
| De Michele, D | 1 |
| Katz, DA | 1 |
| Patronas, NJ | 1 |
| Doppman, JL | 1 |
| Larson, SM | 1 |
| Ito, M | 1 |
| Kufta, CV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A PHASE III TRIAL COMPARING THE USE OF RADIOSURGERY FOLLOWED BY CONVENTIONAL RADIOTHERAPY WITH BCNU TO CONVENTIONAL RADIOTHERAPY WITH BCNU FOR SUPRATENTORIAL GLIOBLASTOMA MULTIFORME[NCT00002545] | Phase 3 | 200 participants (Anticipated) | Interventional | 1994-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for carmustine and Injuries, Radiation
| Article | Year |
|---|---|
Cerebral radiation necrosis: a review of the pathobiology, diagnosis and management considerations.
Topics: Anticoagulants; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brachytherapy; Brain Neoplas | 2013 |
Lung damage from cytotoxic drugs.
Topics: Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carmustine; Chlorambucil; Cyclophosphamide | 1980 |
5 trials available for carmustine and Injuries, Radiation
| Article | Year |
|---|---|
Phase I study of involved-field radiotherapy preceding autologous stem cell transplantation for patients with high-risk lymphoma or Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; | 2004 |
Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; F | 2004 |
High-dose BCNU and autologous progenitor cell transplantation given with intra-arterial cisplatinum and simultaneous radiotherapy in the treatment of high-grade gliomas: benefit for selected patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Damage, Chronic; Brain Neoplasms; | 1996 |
Carboplatin and teniposide concurrent with radiotherapy in patients with glioblastoma multiforme: a phase II study.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytog | 1998 |
Pulmonary toxicity of high-dose chemotherapy for breast cancer: a non-invasive approach to diagnosis and treatment.
Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; C | 1997 |
13 other studies available for carmustine and Injuries, Radiation
| Article | Year |
|---|---|
Total marrow irradiation versus total body irradiation using intensity-modulated helical tomotherapy.
Topics: Bone Marrow; Carmustine; Etoposide; Hematologic Neoplasms; Humans; Radiation Injuries; Radiotherapy | 2023 |
Lack of survival benefit after stereotactic radiosurgery boost for glioblastoma multiforme: randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients
Topics: Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; Female; Glioblastoma; Huma | 2005 |
Complications after combination of chemotherapy and radiation for malignant brain tumours.
Topics: Adult; Bleomycin; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Female; Glioblastoma; Huma | 1982 |
Thyroid dysfunction among long-term survivors of bone marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Carmustine; Child; Child, Preschoo | 1982 |
Prolonged impairment of hematopoiesis after high-dose therapy followed by autologous bone marrow transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transpla | 1995 |
Hematologic toxic reaction to radiation therapy adjuvant to autologous peripheral blood stem cell transplantation for recurrent or refractory Hodgkin disease.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplas | 2000 |
High-dose therapy with hematopoietic cell transplantation for patients with central nervous system involvement by non-Hodgkin's lymphoma.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Carm | 2000 |
Modification of radiation injury to normal tissues by chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Dose-Response | 1975 |
Primary Ewing's sarcoma of the sternum: a case report.
Topics: Bone Neoplasms; Carmustine; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; | 1979 |
Neuropathology of tissues from patients treated by the Brain Tumor Study Group.
Topics: Adult; Anaplasia; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Necrosis; Radiation Inj | 1977 |
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therap | 1991 |
Tumour recurrence vs radionecrosis: an indication for multitrajectory serial stereotactic biopsies.
Topics: Astrocytoma; Biopsy, Needle; Brain; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; | 1989 |
Cerebral necrosis after radiotherapy and/or intraarterial chemotherapy for brain tumors: PET and neuropathologic studies.
Topics: Adolescent; Adult; Aged; Brain; Brain Neoplasms; Carmustine; Child; Child, Preschool; Deoxyglucose; | 1988 |