carmustine has been researched along with Inflammation in 9 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "O6-Benzyl-2'-deoxyguanosine (dBG), a water-soluble inhibitor of O6-methylguanine-DNA methyltransferase (MGMT), potentiates the efficacy of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) against MGMT-positive, BCNU-resistant Daoy human medulloblastoma tumor xenografts in athymic mice (S." | 7.70 | Eradication of human medulloblastoma tumor xenografts with a combination of O6-benzyl-2'-deoxyguanosine and 1,3-bis(2-chloroethyl)1-nitrosourea. ( Kokkinakis, DM; Moschel, RC; Pegg, AE; Schold, SC, 1999) |
| "O6-Benzyl-2'-deoxyguanosine (dBG), a water-soluble inhibitor of O6-methylguanine-DNA methyltransferase (MGMT), potentiates the efficacy of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) against MGMT-positive, BCNU-resistant Daoy human medulloblastoma tumor xenografts in athymic mice (S." | 3.70 | Eradication of human medulloblastoma tumor xenografts with a combination of O6-benzyl-2'-deoxyguanosine and 1,3-bis(2-chloroethyl)1-nitrosourea. ( Kokkinakis, DM; Moschel, RC; Pegg, AE; Schold, SC, 1999) |
| "Use of interstitial BCNU wafers in the treatment of malignant glioma is currently a controversial topic among neurosurgeons." | 2.41 | The role of interstitial BCNU chemotherapy in the treatment of malignant glioma. ( Engelhard, HH, 2000) |
| "Fifteen patients with Hodgkin's or non-Hodgkin's lymphoma receiving HD conditioning chemotherapy and autologous SCT were assessed with respect to oral pain and severity of stomatitis on day -6, 0, +5 to +7, +13 to +15, and +100." | 1.37 | Association of HSV reactivation and pro-inflammatory cytokine levels with the severity of stomatitis after BEAM chemotherapy and autologous SCT. ( Cornely, OA; Keulertz, C; Lövenich, H; Rüping, MJ; Söhngen, D; Vehreschild, JJ; Wieland, U, 2011) |
| " With local delivery of O6BG, the MTD of BCNU in combination with O6BG was increased." | 1.31 | Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model. ( Biser-Rohrbaugh, A; Bunton, TE; Carson, BS; Gabikian, P; Guarnieri, M; Tyler, BM; Weingart, J; Wu, QZ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Herbers, AH | 1 |
| van der Velden, WJ | 1 |
| de Haan, AF | 1 |
| Donnelly, JP | 1 |
| Blijlevens, NM | 1 |
| Song, JM | 1 |
| Qian, X | 1 |
| Teferi, F | 1 |
| Pan, J | 1 |
| Wang, Y | 1 |
| Kassie, F | 1 |
| Galbán, CJ | 1 |
| Bhojani, MS | 1 |
| Lee, KC | 1 |
| Meyer, CR | 1 |
| Van Dort, ME | 1 |
| Kuszpit, KK | 1 |
| Koeppe, RA | 1 |
| Ranga, R | 1 |
| Moffat, BA | 1 |
| Johnson, TD | 1 |
| Chenevert, TL | 1 |
| Rehemtulla, A | 1 |
| Ross, BD | 1 |
| Rüping, MJ | 1 |
| Keulertz, C | 1 |
| Vehreschild, JJ | 1 |
| Lövenich, H | 1 |
| Söhngen, D | 1 |
| Wieland, U | 1 |
| Cornely, OA | 1 |
| Guarnieri, M | 1 |
| Biser-Rohrbaugh, A | 1 |
| Tyler, BM | 1 |
| Gabikian, P | 1 |
| Bunton, TE | 1 |
| Wu, QZ | 1 |
| Weingart, J | 1 |
| Carson, BS | 1 |
| Wu, MP | 1 |
| Tamada, JA | 1 |
| Brem, H | 1 |
| Langer, R | 1 |
| Kokkinakis, DM | 1 |
| Moschel, RC | 1 |
| Pegg, AE | 1 |
| Schold, SC | 1 |
| Engelhard, HH | 1 |
1 review available for carmustine and Inflammation
| Article | Year |
|---|---|
The role of interstitial BCNU chemotherapy in the treatment of malignant glioma.
Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine; Cl | 2000 |
8 other studies available for carmustine and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Impact of palifermin on intestinal mucositis of HSCT recipients after BEAM.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; C-Reactive Prot | 2014 |
Dietary diindolylmethane suppresses inflammation-driven lung squamous cell carcinoma in mice.
Topics: Animals; Carcinoma, Squamous Cell; Carmustine; Cytokines; Diet; Disease Models, Animal; Female; Gene | 2015 |
Evaluation of treatment-associated inflammatory response on diffusion-weighted magnetic resonance imaging and 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography imaging biomarkers.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Dexamethasone; Diffusion Magnetic Reson | 2010 |
Association of HSV reactivation and pro-inflammatory cytokine levels with the severity of stomatitis after BEAM chemotherapy and autologous SCT.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Cytokines; Female; He | 2011 |
Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carmustine; Dose-Resp | 2002 |
In vivo versus in vitro degradation of controlled release polymers for intracranial surgical therapy.
Topics: Animals; Biodegradation, Environmental; Brain Neoplasms; Carmustine; Cellulose, Oxidized; Decanoic A | 1994 |
Eradication of human medulloblastoma tumor xenografts with a combination of O6-benzyl-2'-deoxyguanosine and 1,3-bis(2-chloroethyl)1-nitrosourea.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carmustine; Cerebellar Neoplasms | 1999 |