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carmustine and Granulocytic Leukemia, Chronic

carmustine has been researched along with Granulocytic Leukemia, Chronic in 7 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Research Excerpts

ExcerptRelevanceReference
"Eleven patients with acute myeloblastic leukemia (AML) beyond the first complete remission or chronic myelogenous leukemia (CML) not in first chronic phase received an association of 13."1.29Total body irradiation and high-dose cyclophosphamide, BCNU and VP-16 (CBV) as a new preparatory regimen for allogeneic bone marrow transplantation in patients with advanced hematologic malignancies. ( Bourdin, S; Harousseau, JL; Le Tortorec, S; Mahe, B; Mahe, JM; Mechinaud-Lacroix, F; Milpied, N; Moreau, P; Rapp, MJ; Wu, DP, 1994)
"Fifteen patients had chronic myelogenous leukemia in chronic phase or acute leukemia in first remission (standard risk) and twenty-eight patients with more advanced disease (high risk)."1.28Allogeneic bone marrow transplantation for hematological malignancies following etoposide, cyclophosphamide, and fractionated total body irradiation. ( Andersson, BS; Brunner, LJ; Huan, SD; LeMaistre, CF; Spencer, V; Spinolo, JA; Spitzer, G; Wallerstein, RO; Woo, SY; Yau, JC, 1992)
"Fifteen patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) who were ineligible for allogeneic bone marrow transplantation (BMT) or alpha-interferon therapy were included in this study."1.28Intensive combination chemotherapy and autologous bone marrow transplantation leads to the reappearance of Philadelphia chromosome-negative cells in chronic myelogenous leukemia. ( Deisseroth, AB; Dicke, K; Jagannath, S; Kantarjian, HM; LeMaistre, CF; Spinolo, J; Spitzer, G; Talpaz, M; Yau, J, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's6 (85.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allay, JA1
Dumenco, LL1
Koc, ON1
Liu, L1
Gerson, SL1
Wu, DP1
Milpied, N1
Moreau, P1
Mechinaud-Lacroix, F1
Mahe, B1
Le Tortorec, S1
Rapp, MJ1
Bourdin, S1
Mahe, JM1
Harousseau, JL1
Frischer, H1
Kennedy, EJ1
Chigurupati, R1
Sivarajan, M1
Meloni, G1
Capria, S1
Vignetti, M1
Mandelli, F1
Modena, V1
Yau, JC1
LeMaistre, CF2
Andersson, BS1
Huan, SD1
Wallerstein, RO1
Woo, SY1
Spitzer, G2
Spinolo, JA1
Spencer, V1
Brunner, LJ1
Kantarjian, HM1
Talpaz, M1
Spinolo, J1
Yau, J1
Dicke, K1
Jagannath, S1
Deisseroth, AB1
Kolb, HJ1
Bender-Götze, C1
Haas, RJ1
Holler, E1
Thierfelder, S1
Wilmanns, W1

Trials

1 trial available for carmustine and Granulocytic Leukemia, Chronic

ArticleYear
Bone marrow transplantation for the treatment of leukaemia-results of the Munich Cooperative Group.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:3-4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cyclophosphamid

1989

Other Studies

6 other studies available for carmustine and Granulocytic Leukemia, Chronic

ArticleYear
Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells.
    Blood, 1995, Jun-01, Volume: 85, Issue:11

    Topics: Animals; Base Sequence; Bone Marrow Cells; Carmustine; Drug Resistance; Genetic Vectors; Hematopoiet

1995
Total body irradiation and high-dose cyclophosphamide, BCNU and VP-16 (CBV) as a new preparatory regimen for allogeneic bone marrow transplantation in patients with advanced hematologic malignancies.
    Bone marrow transplantation, 1994, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carm

1994
Glutathione, cell proliferation, and 1,3-bis-(2-chloroethyl)-1-nitrosourea in K562 leukemia.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Buthionine Sulfoximine; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA Repair; DNA, Neoplasm;

1993
Blast crisis of chronic myelogenous leukemia in long-lasting systemic lupus erythematosus: regression of both diseases after autologous bone marrow transplantation.
    Blood, 1997, Jun-15, Volume: 89, Issue:12

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Blast Crisis;

1997
Allogeneic bone marrow transplantation for hematological malignancies following etoposide, cyclophosphamide, and fractionated total body irradiation.
    American journal of hematology, 1992, Volume: 41, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy

1992
Intensive combination chemotherapy and autologous bone marrow transplantation leads to the reappearance of Philadelphia chromosome-negative cells in chronic myelogenous leukemia.
    Cancer, 1991, Jun-15, Volume: 67, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Cycl

1991