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carmustine and Glioma

carmustine has been researched along with Glioma in 539 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Temozolomide (TMZ) and BCNU have demonstrated anti-glioma synergism in preclinical models."9.20BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase ( Ashby, L; Asher, AL; Blaker, BD; Boltes, P; Brick, W; Burri, SH; Heideman, BE; Judy, K; Kelly, R; Norton, HJ; Prabhu, RS; Sumrall, AL; Symanowski, JT; Wiggins, WF, 2015)
"Patients with high-grade glioma can be treated with carmustine wafers or following the Stupp protocol."9.16Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis. ( Aurrecoechea-Obieta, J; Bilbao-Barandica, G; Canales-Llantada, M; Carbayo-Lozano, G; Catalán-Uribarrena, G; Galbarriatu-Gutiérrez, L; Igartua-Azkune, A; Pomposo-Gaztelu, I; Ruiz de Gopegui-Ruiz, E; Undabeitia-Huertas, J, 2012)
"From February 2006 to January 2008, 32 patients were treated at our institution for cerebral supratentorial high grade glioma with surgery and intraoperative placement of carmustine wafers."9.15Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis. ( Brogna, C; D'elia, A; Delfini, R; Frati, A; Salvati, M; Santoro, A, 2011)
"Temozolomide (TMZ) and 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) are reported to be active agents in anaplastic glioma (AG)."9.11Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial. ( Chang, SM; Fine, H; Fink, KL; Greenberg, H; Hess, K; Jaeckle, KA; Junck, L; Kuhn, J; Mehta, M; Prados, MD; Robins, HI; Schold, C; Yung, WK, 2004)
"In preclinical studies, BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea, plus CPT-11 (irinotecan) exhibits schedule-dependent, synergistic activity against malignant glioma (MG)."9.11Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma. ( Affronti, ML; Allen, D; Badruddoja, M; Bigner, DD; Bohlin, C; Dowell, JM; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jackson, S; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Silverman, S; Tourt-Uhlig, S; Vredenburgh, J; Walker, A; Ziegler, K, 2004)
"Irinotecan is a topoisomerase I inhibitor previously shown to be active in the treatment of malignant glioma."9.11Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma. ( Affronti, ML; Allen, D; Bigner, DD; Bohlin, C; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jackson, S; Lentz, C; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Schweitzer, H; Tourt-Uhlig, S; Vredenburgh, J; Walker, A; Ziegler, K, 2004)
"This New Approaches to Brain Tumor Therapy CNS Consortium study sought to determine the maximum-tolerated dose (MTD) of carmustine (BCNU) that can be implanted in biodegradable polymers following resection of recurrent high-grade gliomas and the systemic BCNU exposure with increasing doses of interstitial BCNU."9.10Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial. ( Barker, F; Bruce, J; Fisher, J; Grossman, SA; Hilt, D; Judy, K; Olivi, A; Olsen, J; Piantadosi, S; Tatter, S, 2003)
"The use of thalidomide as an antiangiogenic agent has met with only limited success in the treatment of malignant gliomas."9.10Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas. ( Batchelor, T; Borkowf, CB; Figg, WD; Fine, HA; Lakhani, N; Maher, EA; Purow, BW; Viscosi, E; Wen, PY, 2003)
"We conducted a phase II trial of carmustine (BCNU) plus the O(6)-alkylguanine-DNA alkyltransferase inhibitor O(6)-benzylguanine (O(6)-BG) to define the activity and toxicity of this regimen in the treatment of adults with progressive or recurrent malignant glioma resistant to nitrosoureas."9.10Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. ( Bigner, DD; Colvin, OM; Delaney, S; Dolan, ME; Friedman, AH; Friedman, HS; Gururangan, S; Haglund, MM; Herndon, JE; Kaplan, R; McLendon, RE; Moschel, RC; Pegg, AE; Pluda, J; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Tourt-Uhlig, S, 2002)
"A Phase I study was conducted to determine the safety, toxicity, and maximum tolerated dose of preirradiation chemotherapy using carmustine (BCNU) and cisplatin in the treatment of high-grade gliomas."9.09Phase I evaluation of preirradiation chemotherapy with carmustine and cisplatin and accelerated radiation therapy in patients with high-grade gliomas. ( Buckner, JC; Cascino, TL; Ingle, JN; Pitot, HC; Rajkumar, SV; Schomberg, PJ, 1999)
"The current study was conducted to determine whether the addition of interferon-alpha (IFN-alpha) to treatment with radiation therapy and carmustine (BCNU) improves time to disease progression or overall survival in patients with high-grade glioma."9.09A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma. ( Bernath, AM; Buckner, JC; Cascino, TL; Cole, JT; Hatfield, AK; Kuross, SA; Mailliard, JA; McGinnis, WL; Morton, RF; O'Fallon, JR; Scheithauer, BW; Schomberg, PJ; Steen, PD, 2001)
"To quantify the quality of life of malignant glioma patients treated on a randomized Phase I/II trial of twice-daily radiation therapy (RT) and carmustine, using a modified quality adjusted survival (QAS) model, and to compare the QAS among assigned treatment arms."9.08Quality-adjusted survival analysis of malignant glioma. Patients treated with twice-daily radiation (RT) and carmustine: a report of Radiation Therapy Oncology Group (RTOG) 83-02. ( Curran, WJ; Farnan, N; Fischbach, AJ; Murray, KJ; Nelson, DF; Porter, A; Scott, C, 1995)
"Twenty-two patients, aged 16 to 67, who had malignant gliomas after surgical resection were treated with carmustine and cisplatin intravenous infusion before, during, and after radiotherapy."9.08Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas. ( Chang, CN; Chen, LH; Cheng, WC; Ho, YS; Kiu, MC; Leung, WM; Lin, TK; Ng, KT; Tang, SG; Wong, CW, 1995)
"To find out the effect of carmustine (bischloroethyl-nitrosourea) combined with a biodegradable polymer in the treatment of malignant (Grades III and IV) gliomas, applied locally, at the time of the primary operation."9.08Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study. ( Heiskanen, O; Kalimo, H; Kivipelto, L; Kuurne, T; Timonen, U; Toivanen, P; Unsgaard, G; Valtonen, S, 1997)
"We conducted a Phase I study of bischloroethylnitrosourea (BCNU), cisplatin, and oral etoposide administered prior to and during accelerated hyperfractionated radiation therapy in newly diagnosed high-grade glioma."9.08Phase I and pharmacokinetic study of preirradiation chemotherapy with BCNU, cisplatin, etoposide, and accelerated radiation therapy in patients with high-grade glioma. ( Ames, MM; Bagniewski, PJ; Buckner, JC; Cascino, TL; Marks, RS; Rajkumar, SV; Reid, JM; Schomberg, PJ, 1998)
"We performed a randomized trial to compare survival distributions and toxicity of radiation therapy (RT) and PCNU with those of RT and carmustine (BCNU) in patients with malignant glioma."9.07Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma. ( Arusell, RM; Brown, LD; Buckner, JC; Dinapoli, RP; Earle, JD; Krook, JE; Maier, JA; O'Fallon, JR; Scheithauer, BW; Tschetter, LK, 1993)
"We conducted a phase III trial comparing intravenous (IV) diaziquone (AZQ) and carmustine (BCNU) as single agents in patients with cerebral anaplastic gliomas who had received surgery and radiotherapy."9.07Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma. ( Bigner, DD; Burger, PC; Cairncross, JG; Dropcho, EJ; Halperin, EC; Herndon, JE; Macdonald, DR; Morawetz, R; Schold, SC; Vick, NA, 1993)
"The purpose is twofold: (1) to identify the malignant glioma patients treated in a trial of hyperfractionated radiotherapy (RT) and carmustine (BCNU) who may have been eligible for a stereotactic radiosurgery (SRS) boost; and (2) to compare survival of such patients with that of those considered SRS-ineligible."9.07Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine: a report of Radiation Therapy Oncology Group 83-02. ( Curran, WJ; Fischbach, AJ; Martin, LA; Murray, K; Nelson, JS; Phillips, TL; Schwade, JG; Scott, CB; Weinstein, AS; Yakar, D, 1993)
"This Phase III trial tested the efficacy and safety of intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for the treatment of newly resected malignant glioma, comparing intra-arterial BCNU and intravenous BCNU (200 mg/sq m every 8 weeks), each regimen without or with intravenous 5-fluorouracil (1 gm/sq m three times daily given 2 weeks after BCNU)."9.07A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma. ( Burger, PC; Green, SB; Mahaley, MS; Mealey, J; Ransohff, J; Robertson, JT; Selker, RG; Shapiro, WR; VanGilder, JC, 1992)
" The protocol called for a randomized trial that compared the effects of following 60 Gy radiation/oral hydroxyurea treatment with either carmustine (BCNU) or the combination of procarbazine, lomustine (CCNU), and vincristine (PCV) for two histologic strata: glioblastoma multiforme and other anaplastic gliomas."9.06Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. ( Davis, RL; Gutin, PH; Hannigan, J; Levin, VA; Silver, P; Wara, WM; Wilson, CB, 1990)
"In Brain Tumor Cooperative Group Study 77-02, eleven institutions randomized 603 adult patients with supratentorial malignant glioma to one of four treatment groups following surgery: conventional radiotherapy (6000 cGy in 30-35 fractions) + BCNU, conventional radiotherapy + streptozotocin, hyperfractionated (twice daily) radiotherapy (6600 cGy in 60 fractions) + BCNU, and conventional radiotherapy with misonidazole followed by BCNU."9.06Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma. ( Burger, PC; Deutsch, M; Green, SB; Mealey, J; Paoletti, P; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA, 1989)
"Carmustine (BCNU) was employed as the only chemotherapeutic agent in a Radiation Therapy Oncology Group multimodality study comparing misonidazole-radiosensitized radiation therapy to conventional radiation therapy in 318 patients with malignant glioma."9.06Pulmonary toxicity of carmustine in patients treated for malignant glioma. ( Diener-West, M; Nelson, DF; Pakuris, E; Weinstein, AS, 1986)
"This randomized RTOG study evaluated misonidazole radiosensitized radiation therapy in the treatment of malignant glioma."9.06A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study. ( Carabell, S; Chang, CH; Diener-West, M; Goodman, R; Nelson, DF; Nelson, JS; Sause, WT; Schoenfeld, D; Weinstein, AS, 1986)
"Diaziquone (AZQ) (NSC 182986), a lipid-soluble benzoquinone derivative, is presently being tested in a Phase III clinical trial to determine its efficacy in patients with anaplastic gliomas compared to the more standard 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) treatment following whole-brain irradiation."9.06Sister chromatid exchange induction in patients with anaplastic gliomas undergoing treatment with radiation plus diaziquone or 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Erexson, GL; Kligerman, AD; Schold, SC; Wilmer, JL, 1987)
"Levamisole was evaluated as an immune stimulant in a randomized controlled study of patients with anaplastic gliomas, who had undergone surgical resection and who were also treated with radiotherapy and BCNU chemotherapy."9.05Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model. ( Aronin, P; Dudka, L; Mahaley, MS; Steinbok, P; Zinn, D, 1981)
"Within 3 weeks of definitive surgery, 609 patients with histologically demonstrated, supratentorial malignant glioma were randomized to receive, in addition to 6000 rads of radiotherapy, one of four treatment regimens: carmustine (BCNU), high-dose methylprednisolone, procarbazine, or BCNU plus high-dose methylprednisolone."9.05Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma. ( Alexander, E; Batzdorf, U; Brooks, WH; Byar, DP; Green, SB; Hunt, WE; Mealey, J; Odom, GL; Paoletti, P; Pistenmaa, DA; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Smith, KR; Strike, TA; Walker, MD; Wilson, CB, 1983)
"A randomized prospective study was performed to evaluate misonidazole radiosensitized radiation therapy in the treatment of malignant glioma."9.05A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study. ( Carabell, S; Goodman, RL; Nelson, DF; Nelson, JS; Schoenfeld, D; Wasserman, T; Weinstein, AS, 1983)
"The authors report the results of a randomized study conducted to evaluate the relative benefit of treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) or the combination of procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, and vincristine (PCV) administered after radiation therapy with hydroxyurea to 76 evaluable patients with glioblastoma multiforme and 72 patients with other anaplastic gliomas."9.05Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas. ( Davis, RL; Gutin, PH; Levin, VA; Nutik, S; Resser, KJ; Vestnys, P; Wara, WM; Wilson, CB; Yatsko, K, 1985)
"There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation)."8.95Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery. ( Caire, F; Guyotat, J; Menei, P; Metellus, P; Pallud, J; Roux, A, 2017)
"Carmustine wafers (CW; Gliadel(®) wafers) are approved to treat newly-diagnosed high-grade glioma (HGG) and recurrent glioblastoma."8.91Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis. ( Chowdhary, SA; Newton, HB; Ryken, T, 2015)
"Significant advances in the encapsulation and release of drugs from degradable polymers have led to the Food and Drug Administration approval of Gliadel wafers for controlled local delivery of the chemotherapeutic drug carmustine to high-grade gliomas following surgical resection."8.90Modeling mass transfer from carmustine-loaded polymeric implants for malignant gliomas. ( Kamei, DT; Lee, BS; Pereira, DY; Yip, AT, 2014)
"Carmustine (1,3-bis [2-chloroethyl]-1-nitrosourea, or BCNU) wafers are approved for recurrent glioblastoma and newly diagnosed malignant glioma (MG)."8.84Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience. ( Giese, A; Sabel, M, 2008)
"Widespread use of carmustine wafers (CWs) to treat high-grade gliomas (HGG) has been limited by uncertainties about their efficacy."8.31Newly Diagnosed High-Grade Glioma Surgery with Carmustine Wafers Implantation. A Long-Term Nationwide Retrospective Study. ( Champeaux-Depond, C; Constantinou, P; Jecko, V; Metellus, P; Tuppin, P; Weller, J, 2023)
"Widespread use of carmustine wafers (CW) to treat high-grade gliomas (HGG) has been limited by uncertainties about its efficacy."8.31Recurrent high grade glioma surgery with carmustine wafers implantation: a long-term nationwide retrospective study. ( Champeaux-Depond, C; Constantinou, P; Jecko, V; Metellus, P; Tuppin, P; Weller, J, 2023)
"Implantation of biodegradable Carmustine wafers in patients with malignant glioma is not generally recommended when the ventricular system is opened during tumor resection."8.02Implantation of Carmustine wafers after resection of malignant glioma with and without opening of the ventricular system. ( Abboud, T; Bettag, C; Bock, HC; Hussein, A; Mielke, D; Rohde, V; Sachkova, A, 2021)
"Given that FK506 binding protein 51 (FKBP51) is upregulated in multiple cancers, we designed the present study to characterize its role as well as underlying regulatory mechanisms in glioma in the presence and absence of the chemotherapeutic carmustine (BCNU)."7.96FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells. ( Cui, B; Jiao, YL; Li, H; Liu, S; Liu, XW; Wang, LC; Zhao, YR; Zhou, RF, 2020)
"Carmustine wafers are approved for localized treatment of malignant glioma."7.83Evaluation of serial changes on computed tomography and magnetic resonance imaging after implantation of carmustine wafers in patients with malignant gliomas for differential diagnosis of tumor recurrence. ( Inoue, A; Kikuchi, K; Kohno, S; Kumon, Y; Ohnishi, T; Ohue, S; Seno, T; Suehiro, S; Yamashita, D, 2016)
"Carmustine (BCNU) wafer (Gliadel(®) Wafer) implantation after tumor resection is an approved treatment for high-grade glioma (HGG)."7.83Early Postoperative Expansion of Parenchymal High-intensity Areas on T2-weighted Imaging Predicts Delayed Cerebral Edema Caused by Carmustine Wafer Implantation in Patients with High-grade Glioma. ( Akutsu, H; Ishikawa, E; Kohzuki, H; Masuda, Y; Masumoto, T; Matsuda, M; Matsumura, A; Nakai, K; Okamoto, E; Takano, S; Yamamoto, T, 2016)
"The development of perifocal edema and tumor bed cyst has been reported after implantation of biodegradable carmustine wafers for the treatment of malignant gliomas."7.83The influence of carmustine wafer implantation on tumor bed cysts and peritumoral brain edema. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Sakaida, T; Yokoi, S, 2016)
"Taken together, these data strongly implicate an unexplored role of Nrf2 in glioma resistance to Carmustine and raise the possible use of Nrf2 inhibitors as adjunct to Carmustine for the treatment of malignant glioma."7.81Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells. ( Alleyne, CH; Dhandapani, KM; Prasad, N; Sukumari-Ramesh, S; Vender, JR, 2015)
"Study the feasibility and effectiveness of a treatment associated surgery, intraoperative chemotherapy (carmustine wafers), and concomitant radiochemotherapy (temozolomide) for the management of newly diagnosed, high-grade gliomas."7.79Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases. ( Colin, P; Debreuve, A; Duntze, J; Eap, C; Emery, E; Guillamo, JS; Jovenin, N; Lechapt-Zalcman, E; Litré, CF; Menei, P; Metellus, P; Peruzzi, P; Rousseaux, P; Théret, E, 2013)
" In this study, we have assessed the role of MDT in implementing the TA121 appraisal of the use of carmustine wafers in high grade gliomas."7.78NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice. ( Ashkan, K; Cruickshank, G; Grundy, P; Price, SJ; Whittle, IR, 2012)
"We hypothesized that the observed clinical synergy of orally administered TMZ and carmustine (BCNU) wafers would translate into even greater effectiveness with the local delivery of BCNU and TMZ and the addition of radiotherapy in animal models of malignant glioma."7.76Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model. ( Bekelis, K; Brem, H; Li, KW; Recinos, VR; Sunshine, SB; Tyler, BM; Vellimana, A, 2010)
"Temozolomide (TMZ) and carmustine (BCNU), cancer-drugs usually used in the treatment of gliomas, are DNA-methylating agents producing O6-methylguanine."7.75Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells. ( Cattaneo, E; Magrassi, L; Papait, R; Rigamonti, D, 2009)
"Transferrin (Tf), an iron-transporting serum glycoprotein, which binds to receptors expressed at the surface of most proliferating cells with particularly high expression on erythroblasts and cancer cells, was chosen as the ligand to develop BCNU-loaded biodegradable poly(D,L-lactic acid) nanoparticles (NPs) containing a ligand, which specifically binds to glioma cells, and their anti-tumor ability was evaluated using a C6 glioma model."7.75Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles. ( Albadany, A; Chang, J; Guo, Y; Kang, C; Li, Y; Pu, P; Sheng, J; Yu, S; Yuan, X; Zhang, Z; Zhong, Y, 2009)
" This was of interest because E6 silencing of p53 sensitizes U87MG astrocytic glioma cells to BCNU and temozolomide (TMZ), cytotoxic drugs that are modestly helpful in the treatment of aggressive astrocytic gliomas."7.73Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide. ( Cairncross, JG; Mymryk, JS; Xu, GW, 2005)
"To test in vitro and in vivo the safety and efficacy of a novel chemotherapeutic agent, KM-233, for the treatment of glioma."7.73Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. ( Boehm, P; Divi, MK; Duntsch, C; Jones, T; Krishnamurthy, M; Moore, BM; Sills, A; Wood, G; Zhou, Q, 2006)
"The authors compared and characterized several new classes of camptothecin (CPT) analogs (a total of 22 drugs) directed against human and murine glioma cell lines in vitro, trying to identify CPT analogs that can be used for local therapy in future clinical trials."7.72Camptothecin analogs in malignant gliomas: comparative analysis and characterization. ( Alderson, LM; Amundson, E; Brem, H; Colvin, M; Sampath, P; Tyler, BM; Wall, ME; Wani, MC; Weingart, JD, 2003)
"Using a methylation-specific PCR approach, we assessed the methylation status of the CpG island of MGMT in 92 glioma patients who received temozolomide as first-line chemotherapy or as treatment for relapses."7.72CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. ( Aguirre-Cruz, L; Arribas, L; Balaña, C; Esteller, M; García-Lopez, JL; García-Villanueva, M; Paz, MF; Piquer, J; Pollan, M; Reynes, G; Rojas-Marcos, I; Safont, MJ; Sanchez-Cespedes, M; Yaya-Tur, R, 2004)
" To determine whether forced cell-cycle progression selectively sensitizes tumor cells to alkylating agents, we examined the effects of overexpressing the E2F-1 protein (a positive regulator of cell-cycle progression) on the sensitivity of two malignant human glioma cell lines, U-251 MG and D-54 MG, to BCNU and temozolomide."7.71Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU. ( Fueyo, J; Gomez-Manzano, C; Groves, MD; He, J; Hu, M; Lemoine, MG; Liu, TJ; Mitlianga, P; Yung, AW, 2001)
" We investigated whether quinacrine could improve carmustine therapy in C6 cell cultures and in C6 malignant gliomas implanted subcutaneously into Wistar rats."7.71Quinacrine enhances carmustine therapy of experimental rat glioma. ( Herrera, LA; Ostrosky, P; Reyes, S; Sotelo, J, 2001)
" Here, we examined the effects of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, on the chemosensitivity of human malignant glioma cells."7.70Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells. ( Weller, M; Winter, S, 2000)
"The authors previously demonstrated the presence of cells in primary human malignant gliomas that intrinsically are resistant to carmustine (BCNU)."7.70Identification of transforming growth factor-beta1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display. ( Hoelzinger, DB; Norman, SA; Rankin Shapiro, J; Rhodes, SN; Scheck, AC; Treasurywala, S, 2000)
"We compared sequential single-agent BCNU and procarbazine (PCB) chemotherapy in 31 patients with gliomas [grade IV (10), grade III (15), grade II (6)]."7.68Comparison between BCNU and procarbazine chemotherapy for treatment of gliomas. ( Bromberg, J; Greenberg, HS; Junck, L; Newton, HB; Page, MA, 1993)
"Forty-five patients with malignant gliomas were treated after aggressive surgical resection with alternating intravenous carmustine and cisplatin both during and after radiation therapy."7.68Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas. ( Feun, LG; Janus, TJ; Maor, M; Yung, WK, 1992)
"The effect of simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on human glioma cell growth was investigated."7.68Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells. ( Butti, G; Fumagalli, R; Pagliarini, P; Paoletti, P; Paoletti, R; Soma, MR, 1992)
"Biopsy samples and cultured cells derived from them were obtained from 39 patients with malignant glioma and were analyzed for 1) glutathione (GSH) content; 2) sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or nitrogen mustard (HN2) treatment and 3) the effect of buthionine sulfoximine (BSO) treatment on BCNU and/or HN2 cytotoxicity."7.68Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells. ( Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK, 1991)
"The authors have used phosphorus magnetic resonance spectroscopy to monitor pH changes in malignant gliomas following treatment with intravenous and intra-arterial 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU)."7.67Early metabolic changes following chemotherapy of human gliomas in vivo demonstrated by phosphorus magnetic resonance spectroscopy. ( Arnold, DL; Emrich, J; Feindel, W; Shoubridge, EA; Villemure, JG, 1989)
"The Neuro-oncology Service of the University of California Brain Tumor Research Center conducted a nonrandomized phase II study to evaluate, in patients with recurrent malignant glioma, the benefit of a four-drug combination (BFHM) consisting of carmustine (1,3-bis (2-chloroethyl)-1-nitrosourea), 5-fluorouracil, hydroxyurea, and 6-mercaptopurine."7.67Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas. ( Berger, M; Chamberlain, M; Choucair, A; Da Silva, V; Davis, RL; Levin, VA; Liu, HC; Murovic, J; Phuphanich, S; Seager, M, 1986)
"A therapeutic regimen is described for sedative, analgesic, and anti-emetic effect in patients receiving intra-arterial carmustine (BCNU) for malignant gliomas."7.67Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion. ( Klein, DS; Klein, PW; Mahaley, MS, 1986)
"Using the avian sarcoma virus (ASV) rat glioma model, we have evaluated the in vivo effectiveness of two lipid-soluble folate antagonists, metoprine (DDMP) and its 6-ethyl analog etoprine."7.66Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. ( Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW, 1982)
"We conducted a study to determine the dose-limiting toxicity of an extended dosing schedule of temozolomide (TMZ) when used with a fixed dose of BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea (carmustine), taking advantage of TMZ's ability to deplete O6-alkylguanine-DNA-alkyltransferase and the synergistic activity of these two agents."6.71Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy. ( Abrey, LE; Kleber, M; Malkin, MG; Raizer, JJ, 2004)
"Carmustine (BCNU) has proved to be of value against a variety of primary brain tumors."6.68High-dose carmustine for high-grade gliomas in childhood. ( Biron, P; Bouffet, E; Brunat-Mentigny, M; Khelfaoui, F; Philip, I; Philip, T, 1997)
"Irinotecan is a water-soluble derivative of camptothecin, an alkylator originally extracted from the Chinese tree Camptotheca acuminata."6.42The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors. ( Friedman, HS; Houghton, PJ; Keir, ST, 2003)
"Gliomas are the most common brain tumors in humans."5.51A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care. ( Jie, C; Yang, F; Yi, S; Zhang, G, 2019)
"Gliomas are accompanied with high mortality owning to their invasive peculiarity and vulnerability to drug resistance."5.46MiR-21 enhanced glioma cells resistance to carmustine via decreasing Spry2 expression. ( Hu, J; Liu, JH; Wang, GB; Xue, K, 2017)
"High-grade gliomas are aggressive brain tumours that are extremely challenging to treat effectively."5.35Carmustine implants for the treatment of newly diagnosed high-grade gliomas: a cost-utility analysis. ( Anderson, R; Dyer, M; Garside, R; Mealing, S; Pitt, M; Rogers, G; Somerville, M; Stein, K, 2008)
"Thalidomide is a racemate with known pharmacologic and pharmacokinetic enantioselectivity."5.34Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU. ( Boyle, FM; Davey, RA; Gu, XQ; Mather, LE; Murphy, S, 2007)
"Temozolomide (TMZ) is a methylating agent which prolongs survival when administered during and after radiotherapy in the first-line treatment of glioblastoma and which also has significant activity in recurrent disease."5.33O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. ( Hermisson, M; Kaina, B; Klumpp, A; Nagel, G; Roos, W; Weller, M; Wick, W; Wischhusen, J, 2006)
" Dose-response studies with SH-6 administered to glioma cell lines were performed using a luminescent cell-viability assay (0."5.33Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas. ( Broaddus, WC; Cash, D; Fillmore, H; Van Meter, TE, 2006)
"Fotemustine is a chloroethylnitrosourea with antitumor activity in disseminated melanoma and adult primary brain tumors."5.30Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity. ( Boland, I; Gouyette, A; Lacroix, C; Lellouch-Tubiana, A; Margison, GP; Morizet, J; Parker, F; Pierre-Kahn, A; Poullain, MG; Terrier-Lacombe, MJ; Vassal, G; Vénuat, AM; Watson, AJ, 1998)
" Additionally, we compared the antitumoral effect of protamine with that of another inhibitor of angiogenesis, suramin, and investigated a potential synergistic antitumoral action of low doses of protamine combined with the antineoplastic carmustine."5.30Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine. ( Arrieta, O; Guevara, P; Ortiz, A; Rembao, D; Reyes, S; Sotelo, J, 1998)
"Temozolomide (TMZ) and BCNU have demonstrated anti-glioma synergism in preclinical models."5.20BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase ( Ashby, L; Asher, AL; Blaker, BD; Boltes, P; Brick, W; Burri, SH; Heideman, BE; Judy, K; Kelly, R; Norton, HJ; Prabhu, RS; Sumrall, AL; Symanowski, JT; Wiggins, WF, 2015)
"Patients with high-grade glioma can be treated with carmustine wafers or following the Stupp protocol."5.16Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis. ( Aurrecoechea-Obieta, J; Bilbao-Barandica, G; Canales-Llantada, M; Carbayo-Lozano, G; Catalán-Uribarrena, G; Galbarriatu-Gutiérrez, L; Igartua-Azkune, A; Pomposo-Gaztelu, I; Ruiz de Gopegui-Ruiz, E; Undabeitia-Huertas, J, 2012)
"From February 2006 to January 2008, 32 patients were treated at our institution for cerebral supratentorial high grade glioma with surgery and intraoperative placement of carmustine wafers."5.15Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis. ( Brogna, C; D'elia, A; Delfini, R; Frati, A; Salvati, M; Santoro, A, 2011)
"Anticonvulsant therapy is usually recommended before surgery in all patients affected by high grade glioma who are planned to be treated with Carmustine 1,3-bis [2 chloroetyl]-1-nitrosurea, or BCNU) wafers."5.15Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience. ( Ciccarino, P; d'Avella, D; Del Moro, G; Della Puppa, A; Denaro, L; Lombardi, G; Manara, R; Rossetto, M; Rotilio, A; Scienza, R, 2011)
"Carmustine (1,3-bis[2-chloroetyl]-1-nitrosurea (BCNU)) wafers are approved for the local treatment of newly diagnosed and recurrent malignant glioma."5.14The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series. ( Ciccarino, P; d'Avella, D; Del Moro, G; Della Puppa, A; Denaro, L; Manara, R; Paola Gardiman, M; Rossetto, M; Rotilio, A; Scienza, R, 2010)
"Temozolomide (TMZ) and 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) are reported to be active agents in anaplastic glioma (AG)."5.11Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial. ( Chang, SM; Fine, H; Fink, KL; Greenberg, H; Hess, K; Jaeckle, KA; Junck, L; Kuhn, J; Mehta, M; Prados, MD; Robins, HI; Schold, C; Yung, WK, 2004)
"In preclinical studies, BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea, plus CPT-11 (irinotecan) exhibits schedule-dependent, synergistic activity against malignant glioma (MG)."5.11Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma. ( Affronti, ML; Allen, D; Badruddoja, M; Bigner, DD; Bohlin, C; Dowell, JM; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jackson, S; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Silverman, S; Tourt-Uhlig, S; Vredenburgh, J; Walker, A; Ziegler, K, 2004)
"Irinotecan is a topoisomerase I inhibitor previously shown to be active in the treatment of malignant glioma."5.11Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma. ( Affronti, ML; Allen, D; Bigner, DD; Bohlin, C; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jackson, S; Lentz, C; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Schweitzer, H; Tourt-Uhlig, S; Vredenburgh, J; Walker, A; Ziegler, K, 2004)
"The study involved a randomized comparison of surgery, external beam radiotherapy, and carmustine (BCNU) versus surgery, external beam therapy, interstitial radiotherapy boost, and BCNU in newly diagnosed malignant gliomas."5.10The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine. ( Albright, R; Arena, VC; Barnett, GH; Blackwood, MS; Bloomfield, S; Burger, P; Gilder, JC; Green, S; Hiesiger, E; Hochberg, FH; Malkin, MG; Mealey, JJ; Neal, JH; Olson, J; Robertson, JT; Selker, RG; Shapiro, WR, 2002)
"This New Approaches to Brain Tumor Therapy CNS Consortium study sought to determine the maximum-tolerated dose (MTD) of carmustine (BCNU) that can be implanted in biodegradable polymers following resection of recurrent high-grade gliomas and the systemic BCNU exposure with increasing doses of interstitial BCNU."5.10Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial. ( Barker, F; Bruce, J; Fisher, J; Grossman, SA; Hilt, D; Judy, K; Olivi, A; Olsen, J; Piantadosi, S; Tatter, S, 2003)
"The use of thalidomide as an antiangiogenic agent has met with only limited success in the treatment of malignant gliomas."5.10Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas. ( Batchelor, T; Borkowf, CB; Figg, WD; Fine, HA; Lakhani, N; Maher, EA; Purow, BW; Viscosi, E; Wen, PY, 2003)
"We conducted a phase II trial of carmustine (BCNU) plus the O(6)-alkylguanine-DNA alkyltransferase inhibitor O(6)-benzylguanine (O(6)-BG) to define the activity and toxicity of this regimen in the treatment of adults with progressive or recurrent malignant glioma resistant to nitrosoureas."5.10Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. ( Bigner, DD; Colvin, OM; Delaney, S; Dolan, ME; Friedman, AH; Friedman, HS; Gururangan, S; Haglund, MM; Herndon, JE; Kaplan, R; McLendon, RE; Moschel, RC; Pegg, AE; Pluda, J; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Tourt-Uhlig, S, 2002)
"To investigate the safety of thrice-daily hyperfractionated radiotherapy (RT) given in conjunction with BCNU (carmustine) in high-grade gliomas."5.10Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas. ( Buckner, JC; Dinapoli, RP; Earle, JD; O'Fallon, J; Rao, RD; Thomé, SD, 2002)
"A Phase I study was conducted to determine the safety, toxicity, and maximum tolerated dose of preirradiation chemotherapy using carmustine (BCNU) and cisplatin in the treatment of high-grade gliomas."5.09Phase I evaluation of preirradiation chemotherapy with carmustine and cisplatin and accelerated radiation therapy in patients with high-grade gliomas. ( Buckner, JC; Cascino, TL; Ingle, JN; Pitot, HC; Rajkumar, SV; Schomberg, PJ, 1999)
"The current study was conducted to determine whether the addition of interferon-alpha (IFN-alpha) to treatment with radiation therapy and carmustine (BCNU) improves time to disease progression or overall survival in patients with high-grade glioma."5.09A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma. ( Bernath, AM; Buckner, JC; Cascino, TL; Cole, JT; Hatfield, AK; Kuross, SA; Mailliard, JA; McGinnis, WL; Morton, RF; O'Fallon, JR; Scheithauer, BW; Schomberg, PJ; Steen, PD, 2001)
"Intra-arterial chemotherapy with carmustine (BCNU) and interstitial radiation therapy with the use of stereotactically placed 125I sources are aggressive local therapies for malignant glioma."5.08Evaluating glioma therapies: modeling treatments and predicting outcomes. ( Brothers, M; Cairncross, G; Florell, R; Irish, W; Kirby, S; Macdonald, D; Schold, C, 1995)
" We conducted a randomised, placebo-controlled, prospective study to evaluate the effectiveness of biodegradable polymers impregnated with carmustine to treat recurrent malignant gliomas."5.08Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group. ( Black, K; Brem, H; Brem, S; Burger, PC; Mohr, G; Piantadosi, S; Selker, R; Sisti, M; Vick, NA; Walker, M, 1995)
"To quantify the quality of life of malignant glioma patients treated on a randomized Phase I/II trial of twice-daily radiation therapy (RT) and carmustine, using a modified quality adjusted survival (QAS) model, and to compare the QAS among assigned treatment arms."5.08Quality-adjusted survival analysis of malignant glioma. Patients treated with twice-daily radiation (RT) and carmustine: a report of Radiation Therapy Oncology Group (RTOG) 83-02. ( Curran, WJ; Farnan, N; Fischbach, AJ; Murray, KJ; Nelson, DF; Porter, A; Scott, C, 1995)
"Twenty-two patients, aged 16 to 67, who had malignant gliomas after surgical resection were treated with carmustine and cisplatin intravenous infusion before, during, and after radiotherapy."5.08Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas. ( Chang, CN; Chen, LH; Cheng, WC; Ho, YS; Kiu, MC; Leung, WM; Lin, TK; Ng, KT; Tang, SG; Wong, CW, 1995)
" Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas using single chemotherapy agents such as cyclophosphamide, carboplatin, cisplatin, etoposide and thiotepa or combinations of chemotherapy agents have produced low response rates in the range of 15-20%."5.08Contemporary chemotherapy issues for children with brainstem gliomas. ( Allen, JC; Siffert, J, 1996)
"To find out the effect of carmustine (bischloroethyl-nitrosourea) combined with a biodegradable polymer in the treatment of malignant (Grades III and IV) gliomas, applied locally, at the time of the primary operation."5.08Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study. ( Heiskanen, O; Kalimo, H; Kivipelto, L; Kuurne, T; Timonen, U; Toivanen, P; Unsgaard, G; Valtonen, S, 1997)
"A Phase I study to determine the safety, toxicity, and maximum tolerated dose (MTD) of carmustine (BCNU) and interferon alpha-2a (IFN-a) when combined with radiation as initial therapy in high-grade glioma."5.08Phase I evaluation of radiation combined with recombinant interferon alpha-2a and BCNU for patients with high-grade glioma. ( Buckner, JC; Burch, PA; Cascino, TL; Dinapoli, RP; Rajkumar, SV; Schomberg, PJ, 1998)
"We conducted a Phase I study of bischloroethylnitrosourea (BCNU), cisplatin, and oral etoposide administered prior to and during accelerated hyperfractionated radiation therapy in newly diagnosed high-grade glioma."5.08Phase I and pharmacokinetic study of preirradiation chemotherapy with BCNU, cisplatin, etoposide, and accelerated radiation therapy in patients with high-grade glioma. ( Ames, MM; Bagniewski, PJ; Buckner, JC; Cascino, TL; Marks, RS; Rajkumar, SV; Reid, JM; Schomberg, PJ, 1998)
"We performed a randomized trial to compare survival distributions and toxicity of radiation therapy (RT) and PCNU with those of RT and carmustine (BCNU) in patients with malignant glioma."5.07Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma. ( Arusell, RM; Brown, LD; Buckner, JC; Dinapoli, RP; Earle, JD; Krook, JE; Maier, JA; O'Fallon, JR; Scheithauer, BW; Tschetter, LK, 1993)
"We conducted a phase III trial comparing intravenous (IV) diaziquone (AZQ) and carmustine (BCNU) as single agents in patients with cerebral anaplastic gliomas who had received surgery and radiotherapy."5.07Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma. ( Bigner, DD; Burger, PC; Cairncross, JG; Dropcho, EJ; Halperin, EC; Herndon, JE; Macdonald, DR; Morawetz, R; Schold, SC; Vick, NA, 1993)
"The purpose is twofold: (1) to identify the malignant glioma patients treated in a trial of hyperfractionated radiotherapy (RT) and carmustine (BCNU) who may have been eligible for a stereotactic radiosurgery (SRS) boost; and (2) to compare survival of such patients with that of those considered SRS-ineligible."5.07Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine: a report of Radiation Therapy Oncology Group 83-02. ( Curran, WJ; Fischbach, AJ; Martin, LA; Murray, K; Nelson, JS; Phillips, TL; Schwade, JG; Scott, CB; Weinstein, AS; Yakar, D, 1993)
"This Phase III trial tested the efficacy and safety of intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for the treatment of newly resected malignant glioma, comparing intra-arterial BCNU and intravenous BCNU (200 mg/sq m every 8 weeks), each regimen without or with intravenous 5-fluorouracil (1 gm/sq m three times daily given 2 weeks after BCNU)."5.07A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma. ( Burger, PC; Green, SB; Mahaley, MS; Mealey, J; Ransohff, J; Robertson, JT; Selker, RG; Shapiro, WR; VanGilder, JC, 1992)
"Seventy-nine patients with malignant gliomas (19 anaplastic astrocytomas and 60 glioblastoma multiforme) received 4 cycles of infra-ophthalmic carotid injection of 160 mg carmustine, 2 mg vincristine IV and procarbazine orally 50 mg 3 times daily for 1 week, followed by whole-brain irradiation, with a midpoint dose of 54 Gy/6 weeks."5.07Combined intra-arterial chemotherapy and irradiation of malignant gliomas. ( Hager, B; Hirschberg, H; Nome, O; Watne, K, 1991)
" The protocol called for a randomized trial that compared the effects of following 60 Gy radiation/oral hydroxyurea treatment with either carmustine (BCNU) or the combination of procarbazine, lomustine (CCNU), and vincristine (PCV) for two histologic strata: glioblastoma multiforme and other anaplastic gliomas."5.06Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. ( Davis, RL; Gutin, PH; Hannigan, J; Levin, VA; Silver, P; Wara, WM; Wilson, CB, 1990)
"In Brain Tumor Cooperative Group Study 77-02, eleven institutions randomized 603 adult patients with supratentorial malignant glioma to one of four treatment groups following surgery: conventional radiotherapy (6000 cGy in 30-35 fractions) + BCNU, conventional radiotherapy + streptozotocin, hyperfractionated (twice daily) radiotherapy (6600 cGy in 60 fractions) + BCNU, and conventional radiotherapy with misonidazole followed by BCNU."5.06Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma. ( Burger, PC; Deutsch, M; Green, SB; Mealey, J; Paoletti, P; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA, 1989)
"Within 3 weeks of definitive surgery, 571 adult patients with histologically confirmed, supratentorial malignant gliomas were randomly assigned to receive one of three chemotherapy regimens: BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) alone, alternating courses (every 8 weeks) of BCNU and procarbazine, or BCNU plus hydroxyurea alternating with procarbazine plus VM-26 (epipodophyllotoxin)."5.06Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001. ( Burger, PC; Green, SB; Mahaley, MS; Mealey, J; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA; VanGilder, JC, 1989)
"The Radiation Therapy Oncology Group (RTOG) and the Eastern Cooperative Oncology Group (ECOG) conducted a phase III trial in patients with malignant gliomas to evaluate 4 treatment arms: 1) 60 Gy to the whole brain; 2) 60 Gy plus 10-Gy boost; 3) 60 Gy plus carmustine (BCNU); and 4) 60 Gy plus semustine plus dacarbazine."5.06Combined modality approach to treatment of malignant gliomas--re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: a joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology Group. ( Chang, CH; Diener-West, M; Horton, J; Nelson, DF; Nelson, JS; Schoenfeld, D, 1988)
"Carmustine (BCNU) was employed as the only chemotherapeutic agent in a Radiation Therapy Oncology Group multimodality study comparing misonidazole-radiosensitized radiation therapy to conventional radiation therapy in 318 patients with malignant glioma."5.06Pulmonary toxicity of carmustine in patients treated for malignant glioma. ( Diener-West, M; Nelson, DF; Pakuris, E; Weinstein, AS, 1986)
"This randomized RTOG study evaluated misonidazole radiosensitized radiation therapy in the treatment of malignant glioma."5.06A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study. ( Carabell, S; Chang, CH; Diener-West, M; Goodman, R; Nelson, DF; Nelson, JS; Sause, WT; Schoenfeld, D; Weinstein, AS, 1986)
"Diaziquone (AZQ) (NSC 182986), a lipid-soluble benzoquinone derivative, is presently being tested in a Phase III clinical trial to determine its efficacy in patients with anaplastic gliomas compared to the more standard 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) treatment following whole-brain irradiation."5.06Sister chromatid exchange induction in patients with anaplastic gliomas undergoing treatment with radiation plus diaziquone or 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Erexson, GL; Kligerman, AD; Schold, SC; Wilmer, JL, 1987)
"Levamisole was evaluated as an immune stimulant in a randomized controlled study of patients with anaplastic gliomas, who had undergone surgical resection and who were also treated with radiotherapy and BCNU chemotherapy."5.05Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model. ( Aronin, P; Dudka, L; Mahaley, MS; Steinbok, P; Zinn, D, 1981)
"Within 3 weeks of definitive surgery, 609 patients with histologically demonstrated, supratentorial malignant glioma were randomized to receive, in addition to 6000 rads of radiotherapy, one of four treatment regimens: carmustine (BCNU), high-dose methylprednisolone, procarbazine, or BCNU plus high-dose methylprednisolone."5.05Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma. ( Alexander, E; Batzdorf, U; Brooks, WH; Byar, DP; Green, SB; Hunt, WE; Mealey, J; Odom, GL; Paoletti, P; Pistenmaa, DA; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Smith, KR; Strike, TA; Walker, MD; Wilson, CB, 1983)
"A randomized prospective study was performed to evaluate misonidazole radiosensitized radiation therapy in the treatment of malignant glioma."5.05A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study. ( Carabell, S; Goodman, RL; Nelson, DF; Nelson, JS; Schoenfeld, D; Wasserman, T; Weinstein, AS, 1983)
"Within three weeks of definitive surgical intervention, 467 patients with histologically proved malignant glioma were randomized to receive one of four treatment regimens: semustine (MeCCNU), radiotherapy, carmustine (BCNU) plus radiotherapy, or semustine plus radiotherapy."5.05Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. ( Alexander, E; Batzdorf, U; Brooks, WH; Byar, DP; Green, SB; Hunt, WE; MacCarty, CS; Mahaley, MS; Mealey, J; Owens, G; Ransohoff, J; Robertson, JT; Shapiro, WR; Smith, KR; Strike, TA; Walker, MD; Wilson, CB, 1980)
"The authors report the results of a randomized study conducted to evaluate the relative benefit of treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) or the combination of procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, and vincristine (PCV) administered after radiation therapy with hydroxyurea to 76 evaluable patients with glioblastoma multiforme and 72 patients with other anaplastic gliomas."5.05Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas. ( Davis, RL; Gutin, PH; Levin, VA; Nutik, S; Resser, KJ; Vestnys, P; Wara, WM; Wilson, CB; Yatsko, K, 1985)
"There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation)."4.95Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery. ( Caire, F; Guyotat, J; Menei, P; Metellus, P; Pallud, J; Roux, A, 2017)
" Area covered: The development of interstitial biodegradable carmustine wafers (Gliadel) for treating selected patients with malignant gliomas has resulted in marginal survival benefits in such patients (only approximately 2 months longer than that of those who did not receive the treatment)."4.93Advanced interstitial chemotherapy for treating malignant glioma. ( Kau, YC; Liu, SJ; Tseng, YY, 2016)
"Carmustine wafers (CW; Gliadel(®) wafers) are approved to treat newly-diagnosed high-grade glioma (HGG) and recurrent glioblastoma."4.91Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis. ( Chowdhary, SA; Newton, HB; Ryken, T, 2015)
"Significant advances in the encapsulation and release of drugs from degradable polymers have led to the Food and Drug Administration approval of Gliadel wafers for controlled local delivery of the chemotherapeutic drug carmustine to high-grade gliomas following surgical resection."4.90Modeling mass transfer from carmustine-loaded polymeric implants for malignant gliomas. ( Kamei, DT; Lee, BS; Pereira, DY; Yip, AT, 2014)
"The 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; carmustine) polymer wafer (Gliadel) was developed for use in malignant glioma to deliver higher doses of chemotherapy directly to tumor tissue while bypassing systemic side effects."4.88The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma. ( Nagpal, S, 2012)
"Carmustine (1,3-bis [2-chloroethyl]-1-nitrosourea, or BCNU) wafers are approved for recurrent glioblastoma and newly diagnosed malignant glioma (MG)."4.84Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience. ( Giese, A; Sabel, M, 2008)
" Preclinical and phase I trials have shown the additive or synergistic activity of temozolomide combined with carmustine against solid tumors, including malignant glioma, and the sequence-dependent effects of the combination."4.81Temozolomide in combination with other cytotoxic agents. ( Prados, M, 2001)
"The median survival time of adults with supratentorial malignant glioma treated in clinical studies with surgery, 6 weeks of external-beam radiotherapy, and carmustine (BiCNU) is approximately 1 year."4.79Malignant gliomas in older adults with poor prognostic signs. Getting nowhere, and taking a long time to do it. ( Halperin, EC, 1995)
"Widespread use of carmustine wafers (CWs) to treat high-grade gliomas (HGG) has been limited by uncertainties about their efficacy."4.31Newly Diagnosed High-Grade Glioma Surgery with Carmustine Wafers Implantation. A Long-Term Nationwide Retrospective Study. ( Champeaux-Depond, C; Constantinou, P; Jecko, V; Metellus, P; Tuppin, P; Weller, J, 2023)
"Widespread use of carmustine wafers (CW) to treat high-grade gliomas (HGG) has been limited by uncertainties about its efficacy."4.31Recurrent high grade glioma surgery with carmustine wafers implantation: a long-term nationwide retrospective study. ( Champeaux-Depond, C; Constantinou, P; Jecko, V; Metellus, P; Tuppin, P; Weller, J, 2023)
" Model hydrophobic drugs carmustine and curcumin entrapment propelled glioma cells into apoptosis-based death evaluated by in vitro cytotoxicity assays and Western blot."4.12Supramolecular Hydrogel Based Post-Surgical Implant System for Hydrophobic Drug Delivery Against Glioma Recurrence. ( Ann Paul, R; James, J; Kumar, GSV; Sivakumar, KC; Sunil Jaikumar, V; Wanjale, MV, 2022)
"Factors predicting adverse events following implantation with wafers containing 1,3-bis(2-chloroethyl)-1-nitrosourea (carmustine, BCNU), which is used in local chemotherapy for malignant gliomas (MGs), are unknown."4.12Cerebral Edema Due to Chemotherapeutic Wafer Implantation for Malignant Glioma: Registry Study of Correlation with Perioperative Epileptic Seizures. ( Fujii, Y; Goto, T; Hanaoka, Y; Hardian, RF; Hongo, K; Horiuchi, T; Kato, H; Ogiwara, T, 2022)
"Clinical trial data of Carmustine implant (Gliadel Wafer) in Japanese patients with malignant glioma are limited; thus, we conducted a postmarketing surveillance study to evaluate the safety of Gliadel in real-world clinical practice in Japan."4.02Safety of Gliadel Implant for Malignant Glioma: Report of Postmarketing Surveillance in Japan. ( Iwata, H; Matsuoka, T; Muramoto, K; Nishikawa, R; Sakata, Y, 2021)
"Implantation of biodegradable Carmustine wafers in patients with malignant glioma is not generally recommended when the ventricular system is opened during tumor resection."4.02Implantation of Carmustine wafers after resection of malignant glioma with and without opening of the ventricular system. ( Abboud, T; Bettag, C; Bock, HC; Hussein, A; Mielke, D; Rohde, V; Sachkova, A, 2021)
"Carmustine wafers (CW) are approved to treat newly or recurrent high-grade gliomas (HGG)."3.96Implantation of carmustine wafers (Gliadel ( Champeaux, C; Weller, J, 2020)
"Given that FK506 binding protein 51 (FKBP51) is upregulated in multiple cancers, we designed the present study to characterize its role as well as underlying regulatory mechanisms in glioma in the presence and absence of the chemotherapeutic carmustine (BCNU)."3.96FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells. ( Cui, B; Jiao, YL; Li, H; Liu, S; Liu, XW; Wang, LC; Zhao, YR; Zhou, RF, 2020)
"Although carmustine (Gliadel) wafers improve local tumor control and extend the overall survival in patients with malignant glioma, adverse effects have been documented."3.85Eosinophilic meningitis triggered by implanted Gliadel wafers: case report. ( Ivanova, A; Saito, K; Sato, Y; Takeishi, G; Takeshima, H; Yamasaki, K; Yokogami, K, 2017)
"Carmustine wafers are approved for localized treatment of malignant glioma."3.83Evaluation of serial changes on computed tomography and magnetic resonance imaging after implantation of carmustine wafers in patients with malignant gliomas for differential diagnosis of tumor recurrence. ( Inoue, A; Kikuchi, K; Kohno, S; Kumon, Y; Ohnishi, T; Ohue, S; Seno, T; Suehiro, S; Yamashita, D, 2016)
"Carmustine (BCNU) wafer (Gliadel(®) Wafer) implantation after tumor resection is an approved treatment for high-grade glioma (HGG)."3.83Early Postoperative Expansion of Parenchymal High-intensity Areas on T2-weighted Imaging Predicts Delayed Cerebral Edema Caused by Carmustine Wafer Implantation in Patients with High-grade Glioma. ( Akutsu, H; Ishikawa, E; Kohzuki, H; Masuda, Y; Masumoto, T; Matsuda, M; Matsumura, A; Nakai, K; Okamoto, E; Takano, S; Yamamoto, T, 2016)
"Carmustine (BCNU) wafer implantation has been used in Japanese patients after resection of high-grade glioma (HGG) since 2013."3.83[Intraoperative BCNU Wafer Implantation for High-Grade Glioma--A Questionnaire Targeting Japanese Neurosurgeons]. ( Ishikawa, E; Yamamoto, T, 2016)
"The development of perifocal edema and tumor bed cyst has been reported after implantation of biodegradable carmustine wafers for the treatment of malignant gliomas."3.83The influence of carmustine wafer implantation on tumor bed cysts and peritumoral brain edema. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Sakaida, T; Yokoi, S, 2016)
"Taken together, these data strongly implicate an unexplored role of Nrf2 in glioma resistance to Carmustine and raise the possible use of Nrf2 inhibitors as adjunct to Carmustine for the treatment of malignant glioma."3.81Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells. ( Alleyne, CH; Dhandapani, KM; Prasad, N; Sukumari-Ramesh, S; Vender, JR, 2015)
" The proposed approach fares considerably better than previous approaches in simulations; data on the effectiveness of biodegradable carmustine polymers on recurrent brain malignant gliomas is investigated."3.80Accelerated hazards model based on parametric families generalized with Bernstein polynomials. ( Chen, Y; Hanson, T; Zhang, J, 2014)
"Study the feasibility and effectiveness of a treatment associated surgery, intraoperative chemotherapy (carmustine wafers), and concomitant radiochemotherapy (temozolomide) for the management of newly diagnosed, high-grade gliomas."3.79Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases. ( Colin, P; Debreuve, A; Duntze, J; Eap, C; Emery, E; Guillamo, JS; Jovenin, N; Lechapt-Zalcman, E; Litré, CF; Menei, P; Metellus, P; Peruzzi, P; Rousseaux, P; Théret, E, 2013)
" In this study, we have assessed the role of MDT in implementing the TA121 appraisal of the use of carmustine wafers in high grade gliomas."3.78NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice. ( Ashkan, K; Cruickshank, G; Grundy, P; Price, SJ; Whittle, IR, 2012)
" The purpose of this study was to investigate the efficacy of concurrent therapy with 1,3 bis[2-chloroethyl]-1-nitrosourea (BCNU; carmustine) and Gamma Knife radiosurgery (GKRS; Gamma Knife® Model C, Elekta AB, Stockholm, Sweden) in the C6 rat glioma model."3.78Concurrent treatment with BCNU and Gamma Knife radiosurgery in the rat malignant glioma model. ( Cho, KT; Chung, HT; Jung, HW; Kim, DG; Paek, SH; Park, HW, 2012)
" Here we examine the extent of β-GUS release in small C6 glioma tumors after a single treatment of doxorubicin (DOX), carmustine (BCNU) and tumor necrosis factor α (TNF-α) with positron emission tomography (PET) and the tracer 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-β-d-glucopyronuronate, [(18)F]FEAnGA, which has been proven to be selective for extracellular β-GUS."3.78Induction of β-glucuronidase release by cytostatic agents in small tumors. ( Antunes, IF; de Vries, EF; Di Gialleonardo, V; Dierckx, RA; Elsinga, PH; Haisma, HJ; van Waarde, A; Willemsen, AT, 2012)
" Sixty nude rats were implanted with human glioma cells (U-87 MG) and randomized into three groups: one group received an anti-angiogenic treatment (Sorafenib), a second a cytotoxic drug [1,3-bis(2-chloroethyl)-1-nitrosourea, BCNU (Carmustine)] and a third no treatment."3.77Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects. ( Barbier, EL; Christen, T; Duchamp, O; Farion, R; Fondraz, N; Genne, P; Lemasson, B; Provent, P; Remy, C; Segebarth, C; Tizon, X, 2011)
"The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas."3.76Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells. ( Hirose, Y; Kawase, T; Ohba, S; Yazaki, T; Yoshida, K, 2010)
"Carmustine (BCNU: N,N'-bis[2-chloroethyl]-N-nitrosourea) wafers are a local chemotherapeutic agent for the treatment of malignant glioma."3.76Incorporating BCNU wafers into malignant glioma treatment: European case studies. ( Balossier, A; Dörner, L; Emery, E; Heese, O; Mehdorn, HM; Menei, P; Singh, J, 2010)
"We hypothesized that the observed clinical synergy of orally administered TMZ and carmustine (BCNU) wafers would translate into even greater effectiveness with the local delivery of BCNU and TMZ and the addition of radiotherapy in animal models of malignant glioma."3.76Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model. ( Bekelis, K; Brem, H; Li, KW; Recinos, VR; Sunshine, SB; Tyler, BM; Vellimana, A, 2010)
"A retrospective multicenter study was conducted in 26 French Departments of Neurosurgery to analyze practices of French neurosurgeons using Gliadel, compare the adverse effects and survival with those of previous phase III trials, and assess survival in patients with newly diagnosed malignant gliomas (MG) receiving Gliadel plus radiochemotherapy with temozolomide (TMZ)."3.76Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience. ( Capelle, L; Guyotat, J; Jacquet, G; Loiseau, H; Menei, P; Metellus, P; Parot-Schinkel, E, 2010)
"Temozolomide (TMZ) and carmustine (BCNU), cancer-drugs usually used in the treatment of gliomas, are DNA-methylating agents producing O6-methylguanine."3.75Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells. ( Cattaneo, E; Magrassi, L; Papait, R; Rigamonti, D, 2009)
"Transferrin (Tf), an iron-transporting serum glycoprotein, which binds to receptors expressed at the surface of most proliferating cells with particularly high expression on erythroblasts and cancer cells, was chosen as the ligand to develop BCNU-loaded biodegradable poly(D,L-lactic acid) nanoparticles (NPs) containing a ligand, which specifically binds to glioma cells, and their anti-tumor ability was evaluated using a C6 glioma model."3.75Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles. ( Albadany, A; Chang, J; Guo, Y; Kang, C; Li, Y; Pu, P; Sheng, J; Yu, S; Yuan, X; Zhang, Z; Zhong, Y, 2009)
"DNA alkylating agents including temozolomide (TMZ) and 1,3-bis[2-chloroethyl]-1-nitroso-urea (BCNU) are the most common form of chemotherapy in the treatment of gliomas."3.74The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents. ( Chen, CC; D'Andrea, A; Taniguchi, T, 2007)
"While the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity has been shown to be a beneficial therapy for malignant glioma, it is recognized that clinically significant cerebral edema is a potential adverse effect."3.73Cerebral edema associated with Gliadel wafers: two case studies. ( Goebel, EA; Weber, EL, 2005)
" This was of interest because E6 silencing of p53 sensitizes U87MG astrocytic glioma cells to BCNU and temozolomide (TMZ), cytotoxic drugs that are modestly helpful in the treatment of aggressive astrocytic gliomas."3.73Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide. ( Cairncross, JG; Mymryk, JS; Xu, GW, 2005)
"To test in vitro and in vivo the safety and efficacy of a novel chemotherapeutic agent, KM-233, for the treatment of glioma."3.73Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. ( Boehm, P; Divi, MK; Duntsch, C; Jones, T; Krishnamurthy, M; Moore, BM; Sills, A; Wood, G; Zhou, Q, 2006)
" The best dose (product of 4x10(6) cells) of TF was also combined with carmustine for experimental therapy in rats with C6 malignant glioma."3.73Interstitial transfer factor as adjuvant immunotherapy for experimental glioma. ( Arrieta, O; Estrada-Parra, S; Pedraza-Medina, B; Pérez, R; Pineda, B; Rodriguez-Ropon, A, 2005)
"The authors compared and characterized several new classes of camptothecin (CPT) analogs (a total of 22 drugs) directed against human and murine glioma cell lines in vitro, trying to identify CPT analogs that can be used for local therapy in future clinical trials."3.72Camptothecin analogs in malignant gliomas: comparative analysis and characterization. ( Alderson, LM; Amundson, E; Brem, H; Colvin, M; Sampath, P; Tyler, BM; Wall, ME; Wani, MC; Weingart, JD, 2003)
" Using the human malignant glioma cell lines U87, A172, LN18, and LN229, we examined effects of the PI3K inhibitor LY294002 on both apoptosis and cytotoxicity induced by chemotherapeutic agents, including antimicrotubule agents vincristine and paclitaxel, an alkylating agent 1,3-bis(2-chloroethyl)-1-nitrosourea, a topoisomerase II inhibitor etoposide, and a DNA cross-linking agent cisplatin (cis-diamminedichloroplatinum), and we compared the LY294002-induced enhancement of effects of those agents."3.72Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells. ( Hara, N; Moritake, K; Osago, H; Shingu, T; Terashima, M; Tsuchiya, M; Uemura, T; Yamada, K; Yamasaki, T, 2003)
"Using a methylation-specific PCR approach, we assessed the methylation status of the CpG island of MGMT in 92 glioma patients who received temozolomide as first-line chemotherapy or as treatment for relapses."3.72CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. ( Aguirre-Cruz, L; Arribas, L; Balaña, C; Esteller, M; García-Lopez, JL; García-Villanueva, M; Paz, MF; Piquer, J; Pollan, M; Reynes, G; Rojas-Marcos, I; Safont, MJ; Sanchez-Cespedes, M; Yaya-Tur, R, 2004)
" BCNU, fotemustin, and temozolomide dramatically increased the time of survival of the Hs683 oligodendroglioma-bearing mice, whereas temozolomide only induced a weak but nevertheless statistically significant increase in the U373 glioma-bearing mice."3.71Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy. ( Branle, F; Camby, I; Geurts-Moespot, A; Jeuken, J; Kiss, R; Lefranc, F; Salmon, I; Sprenger, S; Sweep, F, 2002)
"Poorly-differentiated human brain glioma xenografted nude mice were treated with carmustine(1, 3-bis-(2-chloroethyl)-1-nitrosourea, BCNU) and sodium phenylbutyrate (SPB)."3.71[Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug]. ( Dong, J; Huang, Q; Lan, Q; Shi, MG; Sun, ZF, 2002)
" To determine whether forced cell-cycle progression selectively sensitizes tumor cells to alkylating agents, we examined the effects of overexpressing the E2F-1 protein (a positive regulator of cell-cycle progression) on the sensitivity of two malignant human glioma cell lines, U-251 MG and D-54 MG, to BCNU and temozolomide."3.71Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU. ( Fueyo, J; Gomez-Manzano, C; Groves, MD; He, J; Hu, M; Lemoine, MG; Liu, TJ; Mitlianga, P; Yung, AW, 2001)
" We investigated whether quinacrine could improve carmustine therapy in C6 cell cultures and in C6 malignant gliomas implanted subcutaneously into Wistar rats."3.71Quinacrine enhances carmustine therapy of experimental rat glioma. ( Herrera, LA; Ostrosky, P; Reyes, S; Sotelo, J, 2001)
"Eighteen patients had carmustine (BCNU) wafers implanted during reoperation for malignant glioma; three patients had empty, placebo wafers placed."3.70Serial CT and MR imaging of carmustine wafers. ( Chiowanich, P; Cozzens, JW; Gorey, MT; Grenier, Y; Meyer, JR; Prager, JM, 2000)
" Here, we examined the effects of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, on the chemosensitivity of human malignant glioma cells."3.70Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells. ( Weller, M; Winter, S, 2000)
" Survival data from an actual randomized placebo-controlled trial, which evaluates the effectiveness of biodegradable polymers with carmustine to treat malignant gliomas, is used for illustration."3.70Estimating a treatment effect with the accelerated hazards models. ( Chen, YQ; Wang, M, 2000)
"Carmustine and lomustine are nitrosourea antitumor chemotherapeutic agents which were used to determine whether or not they could affect arylamine N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adducts in rat glial tumor cell line (C6 glioma)."3.70Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells. ( Hung, CF, 2000)
"The authors previously demonstrated the presence of cells in primary human malignant gliomas that intrinsically are resistant to carmustine (BCNU)."3.70Identification of transforming growth factor-beta1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display. ( Hoelzinger, DB; Norman, SA; Rankin Shapiro, J; Rhodes, SN; Scheck, AC; Treasurywala, S, 2000)
" The present studies examined the ability of injectable polymeric microspheres, formulated to release carboplatin or BCNU for 2-3 weeks, to enhance survival in a rodent model of surgically-resected glioma."3.70Injectable chemotherapeutic microspheres and glioma I: enhanced survival following implantation into the cavity wall of debulked tumors. ( Bartus, RT; Emerich, DF; Hasler, BP; Hu, Y; LaFreniere, D; Marsh, J; Snodgrass, P; Wiens, T; Winn, SR, 2000)
" The present studies examined the ability of injectable microspheres, formulated to release carboplatin or BCNU for 2-3 weeks, to enhance survival in a rodent model of deep, inoperable glioma."3.70Injectable chemotherapeutic microspheres and glioma II: enhanced survival following implantation into deep inoperable tumors. ( Agostino, M; Bartus, RT; Emerich, DF; LaFreniere, D; Snodgrass, P; Wiens, T; Winn, SR; Xiong, H, 2000)
" The gliomas were obtained from patients who had been treated with carmustine (1,3-bis(2-chloroethyl)-1-nitrosourea, or BCNU)."3.70Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. ( Andion, E; Baylin, SB; Esteller, M; Garcia-Foncillas, J; Goodman, SN; Herman, JG; Hidalgo, OF; Vanaclocha, V, 2000)
"Diffusion MRI could detect water diffusion changes in orthotopic 9L gliomas after doses of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU or carmustine) that resulted in as little as 0."3.70Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. ( Chenevert, TL; Greenberg, HS; Rehemtulla, A; Robertson, PL; Ross, BD; Stegman, LD; Taylor, JM, 2000)
"To evaluate the potential differential effect of pretreatment with pharmacologic doses of the trace element zinc on the chemosensitivity of glioma cells and bone marrow cells for carmustine (BCNU), we performed in vitro and in vivo studies of zinc toxicity as well as of the combined treatment with zinc and the anticancer drug."3.69Effect of pharmacologic doses of zinc on the therapeutic index of brain tumor chemotherapy with carmustine. ( Dougherty, DV; Doz, F; Roosen, N; Rosenblum, ML; Yeomans, KL, 1994)
"The effects of a combination of simvastatin, a cholesterol-lowering agent, and carmustine (BCNU; N,N'-bis(2-chloroethyl)-N-nitrosourea) on experimental C6 glioma were studied in vitro and in vivo."3.69In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. ( Baetta, R; Butti, G; Davegna, C; De Renzis, MR; Fumagalli, R; Magrassi, L; Mazzini, G; Paoletti, R; Pezzotta, S; Soma, MR, 1995)
" It has been shown previously that implantation of controlled-release polymers impregnated with the nitrosourea carmustine (BCNU) extended the period of survival in rats bearing the 9L glioma compared with similar rats treated with systemically administered BCNU."3.69Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain. ( Brem, H; Epstein, JI; Olivi, A; Pinn, M; Tamargo, RJ; Weingart, JD; Wharam, M, 1994)
" This was done using antibromodeoxyuridine immunohistochemical stain and multiple tracer quantitative autoradiography in a C6 rat brain with an implanted glioma."3.69The sequential changes in DNA synthesis, glucose utilization, protein synthesis, and peripheral benzodiazepine receptor density in C6 brain tumors after chemotherapy to predict the response of tumors to chemotherapy. ( Diksic, M; Takeda, N; Yamamoto, YL, 1996)
"Fifteen human glioma cell lines were examined for their sensitivity to 1,3-bis(chloroethyl)-nitrosourea (BCNU, carmustine) and cis-dichlorodiamminoplatinum (cisplatin), the induction of DNA interstrand cross-linking (DNA-ISC) induced by the two agents and cellular O6-alkylguanine alkyltransferase (ATase) activity."3.69DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase. ( Beith, J; Darling, J; Hartley, J; Souhami, R, 1997)
"A total of 379 patients with histologic intracranial low-grade glioma received post-operative radiotherapy (n = 361) and intraarterial carmustine (BCNU) chemotherapy (n = 153)."3.69Survival, prognostic factors, and therapeutic efficacy in low-grade glioma: a retrospective study in 379 patients. ( Berg-Johnsen, J; Egeland, T; Hager, B; Hirschberg, H; Lote, K; Skullerud, K; Stenwig, B; Storm-Mathisen, I, 1997)
"We compared sequential single-agent BCNU and procarbazine (PCB) chemotherapy in 31 patients with gliomas [grade IV (10), grade III (15), grade II (6)]."3.68Comparison between BCNU and procarbazine chemotherapy for treatment of gliomas. ( Bromberg, J; Greenberg, HS; Junck, L; Newton, HB; Page, MA, 1993)
"Eight patients with malignant gliomas were monitored with clinical examinations to study the effects of the combination of intravenous administration of carmustine and infraophthalmic intra-arterial administration of cisplatin on retinal and optic nerve function."3.68Maculopathy caused by intra-arterially administered cisplatin and intravenously administered carmustine. ( Hiesiger, E; Holopigian, K; Kupersmith, MJ; Noble, K; Seiple, WH; Warren, F, 1992)
"Forty-five patients with malignant gliomas were treated after aggressive surgical resection with alternating intravenous carmustine and cisplatin both during and after radiation therapy."3.68Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas. ( Feun, LG; Janus, TJ; Maor, M; Yung, WK, 1992)
"The effect of simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on human glioma cell growth was investigated."3.68Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells. ( Butti, G; Fumagalli, R; Pagliarini, P; Paoletti, P; Paoletti, R; Soma, MR, 1992)
"Biopsy samples and cultured cells derived from them were obtained from 39 patients with malignant glioma and were analyzed for 1) glutathione (GSH) content; 2) sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or nitrogen mustard (HN2) treatment and 3) the effect of buthionine sulfoximine (BSO) treatment on BCNU and/or HN2 cytotoxicity."3.68Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells. ( Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK, 1991)
" The water-soluble ACNU (nimustine) is an alternative to other nitrosoureas in the treatment of gliomas."3.68Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma. ( Dahl, O; Schem, BC, 1991)
"We used human anaplastic glioma xenografts to evaluate the therapeutic efficacy of combinations of alkylating drugs, either 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-(2,5-dioxo-3-piperidyl)-1-nitrosourea (PCNU), or procarbazine, and thiopurines, either 6-mercaptopurine (6MP) or 6-thioguanine (6TG)."3.68Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts. ( Bigner, DD; Bodell, WJ; Elion, GB; Friedman, HS; Schold, SC; Wang, AM, 1991)
"Twenty-six patients with intracerebral tumors (predominantly gliomas) were treated with intraarterial BCNU, VM-26, and cisplatin combined with the systemic administration of VM-26, methotrexate, vincristine, bleomycin, and procarbazine."3.67Combined intraarterial and systemic chemotherapy for intracerebral tumors. ( Benoit, B; Grahovac, Z; Hugenholtz, H; Richard, M; Russell, N; Stewart, DJ, 1987)
"The authors have used phosphorus magnetic resonance spectroscopy to monitor pH changes in malignant gliomas following treatment with intravenous and intra-arterial 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU)."3.67Early metabolic changes following chemotherapy of human gliomas in vivo demonstrated by phosphorus magnetic resonance spectroscopy. ( Arnold, DL; Emrich, J; Feindel, W; Shoubridge, EA; Villemure, JG, 1989)
"Intensive monochemotherapy with carmustine (BCNU) (either 1,050, 1,200, or 1,350 mg/m2) and cryopreserved autologous marrow transplantation was administered to 36 patients with malignant glioma: 27 with progressive disease and nine without progression (adjuvant therapy group)."3.67Intensive 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) monochemotherapy and autologous marrow transplantation for malignant glioma. ( Fay, JW; Herzig, GP; Herzig, RH; Lazarus, HM; Phillips, GL; Schold, C; Wolff, SN, 1986)
"The Neuro-oncology Service of the University of California Brain Tumor Research Center conducted a nonrandomized phase II study to evaluate, in patients with recurrent malignant glioma, the benefit of a four-drug combination (BFHM) consisting of carmustine (1,3-bis (2-chloroethyl)-1-nitrosourea), 5-fluorouracil, hydroxyurea, and 6-mercaptopurine."3.67Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas. ( Berger, M; Chamberlain, M; Choucair, A; Da Silva, V; Davis, RL; Levin, VA; Liu, HC; Murovic, J; Phuphanich, S; Seager, M, 1986)
" We treated 25 consecutive patients (13 pilot patients and 12 protocol patients) with histologically confirmed unresectable grade 3 or 4 malignant gliomas with high-dose BCNU (carmustine) followed by autologous bone marrow transplantation and whole brain irradiation."3.67Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation. ( Corwin, JA; Daly, MB; de los Reyes, RA; Johnson, DB; Lamaster, D; Mosley, KR; Petty, AM; Pierson, WP; Smith, MT; Thompson, JM, 1987)
"A therapeutic regimen is described for sedative, analgesic, and anti-emetic effect in patients receiving intra-arterial carmustine (BCNU) for malignant gliomas."3.67Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion. ( Klein, DS; Klein, PW; Mahaley, MS, 1986)
"Using the avian sarcoma virus (ASV) rat glioma model, we have evaluated the in vivo effectiveness of two lipid-soluble folate antagonists, metoprine (DDMP) and its 6-ethyl analog etoprine."3.66Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. ( Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW, 1982)
"A human medulloblastoma (BN-2) and a glioblastoma (BN-3) which were previously established in nude mice were used to determine the effect of combined modality therapy with gamma-radiation, and three chemotherapeutic agents, procarbazine, 1,4-cyclohexadiene-1,4-dicarbamic acid, 2,5-bis(1-aziridinyl)-3,6-dioxo diethylester (AZQ), and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)."3.66Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model. ( Feola, J; Houchens, DP; Ovejera, AA; Slagel, DE, 1982)
"Symptomatic pulmonary disease occurred in 20 per cent of 93 patients with anaplastic gliomas being treated with carmustine (BCNU)."3.66Prediction of BCNU pulmonary toxicity in patients with malignant gliomas: an assessment of risk factors. ( Aronin, PA; Donohue, JF; Dudka, L; Mahaley, MS; Moore, P; Rudnick, SA; Selker, RG, 1980)
"Intracerebral murine glioma 26 was used as a model system for evaluating two-drug combinations of antitumor agents, BCNU was combined with either procarbazine, dianhydrogalactitol, or ellipticine."3.66Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens. ( Levin, VA; Wilson, CB, 1978)
"High grade gliomas are associated with poor prognosis and high mortality."2.94A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma. ( Black, KL; Chu, RM; Hu, JL; Mazer, MJ; Nuno, M; Phuphanich, S; Rudnick, JD; Sarmiento, JM; Uy, B; Wang, H; Wheeler, CJ; Yu, JS, 2020)
" Subgaleal effusion was the most common adverse event, presenting in 7 patients (46."2.79Safety evaluation of high-dose BCNU-loaded biodegradable implants in Chinese patients with recurrent malignant gliomas. ( Chen, YS; Chen, ZH; Chen, ZP; Gao, WC; Guo, CC; Ke, C; Li, X; Lin, FH; Lv, YC; Mou, YG; Sai, K; Wang, J; Yang, QY; Zeng, J; Zhang, XH; Zhong, MG, 2014)
"We conducted a study to determine the dose-limiting toxicity of an extended dosing schedule of temozolomide (TMZ) when used with a fixed dose of BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea (carmustine), taking advantage of TMZ's ability to deplete O6-alkylguanine-DNA-alkyltransferase and the synergistic activity of these two agents."2.71Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy. ( Abrey, LE; Kleber, M; Malkin, MG; Raizer, JJ, 2004)
"To investigate the therapeutic effect of photodynamic therapy (PDT) combined with interstitial chemo- therapy on gliomas after microsurgery."2.71[Effect of photodynamic therapy combined with interstitial chemotherapy for gliomas]. ( Chen, LF; Ke, YQ; Wang, SQ; Xu, RX; Yang, ZL, 2005)
"Histology included anaplastic astrocytoma (AA) in 15 patients and glioblastoma multiforme (GBM) in 49 patients."2.68Accelerated hyperfractionated radiation therapy for malignant glioma. A phase II study. ( Antunovic, V; Djuric, L; Grujicic, D; Jeremic, B; Shibamoto, Y, 1995)
" Interstitial chemotherapy with BCNU-polymer with subsequent radiation therapy appears to be safe as an initial therapy."2.68The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial. ( Brem, H; Burger, PC; Ewend, MG; Greenhoot, J; Piantadosi, S; Sisti, M, 1995)
"Carmustine (BCNU) has proved to be of value against a variety of primary brain tumors."2.68High-dose carmustine for high-grade gliomas in childhood. ( Biron, P; Bouffet, E; Brunat-Mentigny, M; Khelfaoui, F; Philip, I; Philip, T, 1997)
"Sixteen patients with intracerebral tumors received intraarterial cisplatin, teniposide, and BCNU combined with intravenous cisplatin, teniposide, and cytosine arabinoside."2.67Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors. ( Belanger, G; Benoit, B; DaSilva, V; Grahovac, Z; Hugenholtz, H; Richard, MT; Russell, N; Stewart, DJ, 1993)
"Malignant gliomas have been difficult to treat with chemotherapy."2.67Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. ( Black, KL; Brem, H; Burger, PC; Ciric, IS; Cozzens, JW; Eller, TW; Friedman, AH; Mahaley, MS; Schold, SC; Vick, NA, 1991)
"Pulmonary fibrosis is the end point of progressive functional disorder of respiratory mechanism and alveolo-capillary gas exchanges."2.66Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention. ( Butti, G; Gaetani, P; Knerich, R; Rossi, A; Silvani, V; Spanu, G, 1987)
"Patients with anaplastic astrocytoma had a median survival of 27 months as compared to 8 months for patients with glioblastoma."2.65Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study. ( Chang, CH; Horton, J; Kramer, S; Nelson, JS; Perez-Tamayo, R; Salazer, O; Schoenfeld, D; Tsukada, Y; Weinstein, A, 1983)
"Thirteen of 19 (68%) evaluable primary brain tumors and 9 of 16 (56%) evaluable brain metastases responded."2.65Intracarotid chemotherapy with a combination of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), cis-diaminedichloroplatinum (cisplatin), and 4'-O-demethyl-1-O-(4,6-O-2-thenylidene-beta-D-glucopyranosyl) epipodophyllotoxin (VM-26) in the treatment of primary ( Addison, D; Benoit, B; Dennery, J; Grahovac, Z; Hugenholtz, H; Maroun, JA; Peterson, E; Richard, MT; Russell, N; Stewart, DJ, 1984)
"Sixty-five patients with malignant brain tumors were treated with a combination of BCNU (100 mg/m2 qd X 1) and procarbazine (100 mg/m2 qd X 14); the cycle was repeated in 1 month and then on a 6-week schedule with procarbazine being given for 21 days."2.64BCNU (NSC-409962) and procarbazine (NSC-77213) treatment for malignant brain tumors. ( Boldrey, EB; Crafts, DC; Elashoff, RM; Enot, KJ; Levin, VA; Pischer, TL; Schultz, MJ; Seager, M; Wilson, CB, 1976)
"Malignant glioma is one of the most challenging central nervous system (CNS) diseases, which is typically associated with high rates of recurrence and mortality."2.50Combining microbubbles and ultrasound for drug delivery to brain tumors: current progress and overview. ( Fan, CH; Liu, HL; Ting, CY; Yeh, CK, 2014)
"Malignant gliomas are the most frequently occurring, devastating primary brain tumors, and are coupled with a poor survival rate."2.49Current status of local therapy in malignant gliomas--a clinical review of three selected approaches. ( Juratli, TA; Krex, D; Schackert, G, 2013)
"Malignant gliomas are very difficult neoplasms for clinicians to treat."2.44Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience. ( Bohan, E; Brem, H; Hussain, N; Kleinberg, L; Lawson, HC; Olivi, A; Park, MC; Sampath, P; Weingart, J, 2007)
"High-grade glioma is a devastating disease that leaves the majority of its victims dead within 2 years."2.44Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies. ( Kleinberg, LR; Lin, SH, 2008)
"Malignant gliomas are among the most devastating human cancers."2.43Local treatment of malignant brain tumors using implantable chemotherapeutic polymers. ( Brem, H; Brem, S; Gallia, GL, 2005)
"Radiation therapy for five primary brain tumors is discussed based on the results of prospective trials."2.42[Evidence-based radiation therapy for primary brain tumors]. ( Kono, T; Nankoh, S; Shibamoto, Y; Taniguchi, H; Tomita, N; Tsuji, H, 2003)
"Irinotecan is a water-soluble derivative of camptothecin, an alkylator originally extracted from the Chinese tree Camptotheca acuminata."2.42The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors. ( Friedman, HS; Houghton, PJ; Keir, ST, 2003)
"New approaches to malignant glioma are being actively investigated."2.42Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. ( Brem, H; Guerin, C; Lawson, HC; Olivi, A; Weingart, JD, 2004)
"Use of interstitial BCNU wafers in the treatment of malignant glioma is currently a controversial topic among neurosurgeons."2.41The role of interstitial BCNU chemotherapy in the treatment of malignant glioma. ( Engelhard, HH, 2000)
"High-grade malignant gliomas are inevitably fatal, despite every effort to improve this prognosis, including various radiotherapeutic modalities, radio- and chemotherapeutic associations, and combinations of several drugs."2.41High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults. ( Basso, U; Brandes, AA; Monfardini, S; Palmisano, V; Pasetto, LM, 2001)
"Carmustine (BCNU) has been shown to have limited activity at conventional dosage but is still the standard chemotherapy."2.41[Role of high-dose chemotherapy with hemopoietic stem-cell support in the treatment of adult patients with high-grade glioma]. ( Alcaraz, L; Benboubker, L; Bergemer-Fouquet, AM; Calais, G; Colombat, P; Destrieux, C; Jan, M; Linassier, C, 2001)
"Contemporary treatment of malignant brain tumors has been hampered by problems with drug delivery to the tumor bed."2.41Drug delivery to tumors of the central nervous system. ( Brem, H; Langer, R; Lesniak, MS, 2001)
" Given the localised nature of the drug in the brain tissue, no direct pharmacokinetic measurements have been made in humans after implantation of a carmustine wafer."2.41Pharmacokinetics of the carmustine implant. ( Fleming, AB; Saltzman, WM, 2002)
"Human malignant gliomas are karyotypically heterogeneous, composed of many cellular populations and isolated cell types identifiable by cytogenetic techniques."2.37The subpopulations and isolated cell types of freshly resected high grade human gliomas: their influence on the tumor's evolution in vivo and behavior and therapy in vitro. ( Shapiro, JR; Shapiro, WR, 1985)
"In small cell lung cancer initial high dose therapy followed by non-cross-resistant regimens may prove effective."2.37High dose chemotherapy in solid tumours in adults. ( Peters, W; Souhami, R, 1986)
"Gliomas are the most common brain tumors in humans."1.51A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care. ( Jie, C; Yang, F; Yi, S; Zhang, G, 2019)
"Here, we report a case of external hydrocephalus caused by Gliadel-induced eosinophilic meningitis that has been previously reported in only 1 case and can be diagnosed by time-spatial labeling inversion pulse magnetic resonance imaging (time-SLIP MRI)."1.48Novel Application of Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging for Diagnosis of External Hydrocephalus. ( Abe, M; Adachi, K; Hirose, Y; Kumai, T; Murayama, K; Nakae, S, 2018)
"Gliomas are accompanied with high mortality owning to their invasive peculiarity and vulnerability to drug resistance."1.46MiR-21 enhanced glioma cells resistance to carmustine via decreasing Spry2 expression. ( Hu, J; Liu, JH; Wang, GB; Xue, K, 2017)
" Additionally, medical records of 163 patients treated with BCNU for recurrent glioma WHO grade II to IV were retrospectively evaluated for BCNU-related side effects classified according to the National Cancer Institute Common Toxicity Criteria for Adverse Events (CTCAE) version 2."1.43Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients. ( Ahmadi, R; Bermejo, JL; Capper, D; Chatziaslanidou, D; Exner, J; Herold-Mende, C; Jungk, C; Unterberg, A; von Deimling, A, 2016)
" Several adverse events(AEs)associated with implantation of BCNU wafers, including cerebral edema or cyst formation, are recognized."1.42[Risk Factors for Adverse Events after Implantation of BCNU Wafers in High-grade Gliomas]. ( Asaoka, K; Endo, S; Houkin, K; Ishi, Y; Kamoshima, Y; Kobayashi, H; Motegi, H; Terasaka, S; Yamaguchi, S; Yoshida, M, 2015)
"According to different treatments, glioma U251 cells were randomly divided into blank group, Lipofectamine group, siRNA-Gli1 group, BCNU group and combination group."1.42Knockdown of Gli1 by small-interfering RNA enhances the effects of BCNU on the proliferation and apoptosis of glioma U251 cells. ( Bai, J; Dong, X; Guo, W; Tian, H; Yang, X, 2015)
" The in vitro anticancer efficacy of PAA-GO-BCNU was demonstrated by a 30% increase in DNA interstrand cross-linking and a 77% decrease in the IC(50) value toward GL261 compared with the same dosage of free drug."1.38Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide. ( Chen, JP; Chen, PY; Huang, CY; Hung, SC; Li, SM; Lu, YJ; Ma, CC; Tsai, HC; Wei, KC; Yang, HW, 2012)
"Malignant gliomas are the most destructive type of brain cancer."1.37Pro-apoptotic role of integrin β3 in glioma cells. ( Kim, JH; Lee, WH; Suk, K; Zheng, LT, 2011)
"Malignant glioma is a common and severe primary brain tumor with a high recurrence rate and an extremely high mortality rate within 2 years of diagnosis, even when surgical, radiological, and chemotherapeutic interventions are applied."1.36Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment. ( Chen, JP; Chen, PY; Chen, SM; Chu, PC; Chuang, JI; Feng, LY; Hsueh, C; Hua, MY; Huang, CY; Liu, HL; Lu, YJ; Lyu, LA; Ma, YH; Shin, JW; Tsai, HC; Tseng, IC; Wang, JJ; Wei, KC; Wu, T; Yang, HW; Yen, TC, 2010)
"Malignant gliomas are the most common primary brain tumors."1.35Possible novel therapy for malignant gliomas with secretable trimeric TRAIL. ( Billiar, TR; Jeong, M; Jeun, SS; Kim, BM; Kim, CY; Ko, Y; Kwon, YS; Park, SH; Robbins, PD; Seol, DW; Song, KW, 2009)
"High-grade gliomas are aggressive brain tumours that are extremely challenging to treat effectively."1.35Carmustine implants for the treatment of newly diagnosed high-grade gliomas: a cost-utility analysis. ( Anderson, R; Dyer, M; Garside, R; Mealing, S; Pitt, M; Rogers, G; Somerville, M; Stein, K, 2008)
"Thalidomide is a racemate with known pharmacologic and pharmacokinetic enantioselectivity."1.34Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU. ( Boyle, FM; Davey, RA; Gu, XQ; Mather, LE; Murphy, S, 2007)
"Histology included anaplastic astrocytoma (60) (AA), and glioblastoma multiforme (312) (GBM)."1.34Imaging response in malignant glioma, RTOG 90-06. ( Berkey, B; Curran, WJ; Fishbach, J; Jones, CU; Lustig, RA; Movsas, B; Scarantino, C; Seiferheld, W; Simpson, JR; Yung, AW, 2007)
"While cells from untreated gliomas often have over-representation of chromosome 7, chromosome 22 is typically under-represented."1.33Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Hank, NC; Scheck, AC; Shapiro, JR, 2006)
"Temozolomide (TMZ) is a methylating agent which prolongs survival when administered during and after radiotherapy in the first-line treatment of glioblastoma and which also has significant activity in recurrent disease."1.33O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. ( Hermisson, M; Kaina, B; Klumpp, A; Nagel, G; Roos, W; Weller, M; Wick, W; Wischhusen, J, 2006)
"A substantial percentage of brain tumors overexpressed biomarkers associated with drug resistance, including MGMT (67%), GSTP1 (49%), and mutant p53 (41%)."1.33In vitro drug response and molecular markers associated with drug resistance in malignant gliomas. ( Barger, G; Brem, H; Brem, S; Fruehauf, JP; Huang, W; Parker, R; Sloan, A, 2006)
"Cell lines derived from primary and recurrent brain tumors from the same patient and cells selected for resistance to the chemotherapeutic agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) were used to identify antiproliferative effects of this extract when used alone and in conjunction with BCNU."1.33Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. ( Clark, WD; Hank, NC; Perry, K; Scheck, AC, 2006)
" Dose-response studies with SH-6 administered to glioma cell lines were performed using a luminescent cell-viability assay (0."1.33Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas. ( Broaddus, WC; Cash, D; Fillmore, H; Van Meter, TE, 2006)
"In all cell lines tested, treatment of glioblastoma multiforme cells with BCNU followed by AMD3100 results in synergistic antitumor efficacy in vitro."1.33CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. ( Chan, JA; Kung, AL; Redjal, N; Segal, RA, 2006)
" The LD50 values for MX2, M2 and BCNU were 10."1.31An investigation of the cytotoxicity of the morpholino anthracycline MX2 against glioma cells in vitro. ( Hill, JS; Kaye, AH; Park, SJ, 2000)
"Treatment of malignant brain tumors with chloroethylnitrosoureas (CENUs) in addition to surgical resection and radiotherapy remains the foundation of glioma therapy."1.31Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter. ( Chen, ZP; Huang, Q; Pan, J; Sun, ZF; Wang, AD; Zhou, LY, 2001)
" With a similar dosing schedule, BCNU produced no tumor-free animals, six regressions, and one drug-related death at its optimum of 30 mg/kg/dose."1.302-Chloroethyl-3-sarcosinamide-1-nitrosourea, a novel chloroethylnitrosourea analogue with enhanced antitumor activity against human glioma xenografts. ( Alley, MC; Camalier, RF; Carter, CA; Dykes, DJ; Hollingshead, MG; Malspeis, L; Marcantonio, D; Panasci, LC; Sausville, EA, 1997)
"Fotemustine is a chloroethylnitrosourea with antitumor activity in disseminated melanoma and adult primary brain tumors."1.30Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity. ( Boland, I; Gouyette, A; Lacroix, C; Lellouch-Tubiana, A; Margison, GP; Morizet, J; Parker, F; Pierre-Kahn, A; Poullain, MG; Terrier-Lacombe, MJ; Vassal, G; Vénuat, AM; Watson, AJ, 1998)
" Additionally, we compared the antitumoral effect of protamine with that of another inhibitor of angiogenesis, suramin, and investigated a potential synergistic antitumoral action of low doses of protamine combined with the antineoplastic carmustine."1.30Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine. ( Arrieta, O; Guevara, P; Ortiz, A; Rembao, D; Reyes, S; Sotelo, J, 1998)
"Animals with brain tumors treated with 4HC had a median survival span of 77 days compared to the median survival of 21 days in BCNU-treated animals and median survival of 14 days in untreated animals."1.29Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas. ( Brem, H; Buahin, KG; Colvin, OM; Domb, A; Epstein, JI; Judy, KD; Olivi, A, 1995)
"Carmustine is a chemotherapeutic agent frequently employed in the treatment of malignant brain tumors."1.29Carmustine toxicity presenting as a lobar infiltrate. ( Byron, WA; Lee, TH; Patterson, DL; Wiemann, MC, 1993)
"BCNU treatment of both glioma cell lines led to reduced nicotinamide adenine dinucleotide levels, indicating activation of PARP."1.29Identification of a 116 kDa protein able to bind 1,3-bis(2-chloroethyl)-1-nitrosourea-damaged DNA as poly(ADP-ribose) polymerase. ( Berger, NA; Desnoyers, S; Malapetsa, A; Noë, AJ; Panasci, LC; Poirier, GG, 1996)
"Recurrent gliomas are most often treated by chemotherapy."1.29Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines. ( Liang, BC, 1996)
"Forty-three patients with brain tumors were entered into the study."1.29Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy. ( Kowada, M; Mineura, K; Watanabe, K; Yanagisawa, T; Yasui, N, 1996)
" A method to individualize IA drug dosage is needed to provide each patient with the safest, most effective dose."1.28Effect of intra-arterial cisplatin and 1,3-bis(2chloroethyl)-1-nitrosourea (BCNU) dosage on radiographic response and regional toxicity in malignant glioma patients: proposal of a new method of intra-arterial dosage calculation. ( Bobo, H; Kapp, JP; Vance, R, 1992)
"Berberine was evaluated for antitumor activity against malignant brain tumors."1.28Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors. ( Dougherty, DV; Rosenblum, ML; Zhang, RX, 1990)
" The single dosage was 100 mg/m2 and repeated every 4-6 weeks."1.28[Internal carotid arterial BCNU perfusion in the treatment of cerebral glioma]. ( Wu, ZL, 1989)
"Human gliomas were grown as permanent tissue cultures and xenografts in nude mice."1.28Establishment and characterization of human glioblastoma cell lines in vitro and their xenografts in nude mice. ( Fischer, H; Hutter, KJ; Kunze, S; Schwechheimer, K; Sturm, V; Wowra, B; Zeller, WJ, 1989)
"Four who had nonirradiated anaplastic astrocytomas all responded and survived for 38+ to 48."1.27Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study. ( Avellanosa, AM; Barua, NR; Hong, CI; Patel, A; West, CR, 1983)
"Metronidazole, 1."1.27Feasibility study of combining metronidazole with chemotherapy. ( Bélanger, R; Crook, AF; Heringer, R; Hopkins, HS; Hugenholtz, H; Maroun, JA; Richard, MT; Stewart, DJ; Yan, RC; Young, V, 1983)
" BCNU in combination with Vincristine and Procarbazine every 6 weeks."1.27Complications associated with intra-arterial BCNU administered in combination with vincristine and procarbazine for the treatment of malignant brain tumors. ( Balsys, R; Bremer, AM; Duarte, P; Gonzalez, N; Kleriga, E; Miller, RI; Nguyen, TQ; Northup, HM, 1984)
"Two human brain tumors which were previously established in nude mice were used to determine antitumor efficacy of various therapeutic agents."1.27Human brain tumor xenografts in nude mice as a chemotherapy model. ( Houchens, DP; Ovejera, AA; Riblet, SM; Slagel, DE, 1983)
"A combination chemotherapy regimen for brain tumors was developed, based on investigations of the survival of animals harboring the intracerebral 9L rat brain-tumor model and on analyses of their clonogenic tumor cells."1.27Improved treatment of a brain-tumor model. Part 2: Sequential therapy with BCNU and 5-fluorouracil. ( Dougherty, DV; Gerosa, MA; Rosenblum, ML; Wilson, CB, 1983)
" In the case of 2,5-diaziridinyl-3,6-bis(carboethoxyamine)-1,4-benzoquinone, we observed about an 80-fold difference between its in vitro half-life of 40."1.27Application of in vivo and in vitro pharmacokinetics for physiologically relevant drug exposure in a human tumor clonogenic cell assay. ( Ali-Osman, F; Dougherty, D; Giblin, J; Rosenblum, ML, 1987)
"Positive results were obtained in the treatment of oligodendrogliomas and astrocytomas grade III and IV."1.27Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations. ( Jaksche, H; Loew, F; Papavero, L, 1987)
" Comparison of the slope of the regression line for the dose-response curve and the interpolated ID90 for each drug showed that U251-MG was equally sensitive to aziridinylbenzoquinone and dianhydrogalactitol in all three assays."1.27Comparison of in vitro cloning assays for drug sensitivity testing of human brain tumours. ( Berens, ME; Dougherty, DV; Giblin, JR; Hoifodt, HK; Rosenblum, ML; Tveit, K, 1988)
" A recently described statistical model, which employs the LD50 dose of new agents in mice, was used to estimate the achievable peak plasma concentration (PPC) of SarCNU."1.27The cytotoxicity of sarcosinamide chloroethylnitrosourea (SarCNU) and BCNU in primary gliomas and glioma cell lines: analysis of data in reference to theoretical peak plasma concentrations in man. ( Feindel, W; McQuillan, A; Panasci, L; Rivas, J; Skalski, V, 1988)
"Multimodal treatment of malignant gliomas is routinely used at New York University Medical Center."1.26Malignant glioma. Results of combined modality therapy. ( Borok, TL; Carella, RJ; Cooper, JS; Ransohoff, J, 1982)
" Dose-response curves from some clones differed statistically (log-probit analysis) from those of others, and when the curves were parallel, their 50% effective doses often differed."1.26Heterogeneous chemosensitivities of subpopulations of human glioma cells in culture. ( Shapiro, JR; Shapiro, WR; Yung, WK, 1982)
"It is concluded that BCNU causes pulmonary fibrosis that is primarily but not necessarily dose-related and may not be reversible."1.261,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced pulmonary fibrosis. ( Bellot, P; Cohen, M; Fisher, ER; Jacobs, SA; Moore, PB; Selker, RG; Wald, M, 1980)
" Dose-response curves showed that the inhibitory responses after 1 day in these pretreated cultures exposed to 0."1.26Combined growth-inhibitory responses and ultrastructural alterations produced by 1,3-bis(2-chloroethyl)-1-nitrosourea and dexamethasone in rat glioma cell cultures. ( Boler, RK; Grasso, RJ; Johnson, CE; Moore, NA, 1977)
" A comparison of the in vitro colony-forming capacity of treated and untreated tumor cells permits calculation of the fraction of clonogenic tumor cells surviving in vivo therapy; The plateau that we previously observed o the BCNU dose-response curve is not the result of repair of potentially lethal damage, since no change in the 0."1.26Brain-tumor therapy. Quantitative analysis using a model system. ( Knebel, KD; Rosenblum, MK; Vasquez, DA; Wilson, CB, 1977)

Research

Studies (539)

TimeframeStudies, this research(%)All Research%
pre-1990189 (35.06)18.7374
1990's128 (23.75)18.2507
2000's125 (23.19)29.6817
2010's81 (15.03)24.3611
2020's16 (2.97)2.80

Authors

AuthorsStudies
Kokoshka, JM1
Ireland, CM1
Barrows, LR1
Mohler, ML2
Kang, GS2
Hong, SS1
Patil, R2
Kirichenko, OV2
Li, W2
Rakov, IM1
Geisert, EE2
Miller, DD2
Wanjale, MV1
Sunil Jaikumar, V1
Sivakumar, KC1
Ann Paul, R1
James, J1
Kumar, GSV1
Fujii, Y1
Ogiwara, T1
Kato, H1
Hanaoka, Y1
Hardian, RF1
Goto, T1
Hongo, K1
Horiuchi, T1
Chen, S1
Qiu, Q1
Wang, D1
She, D1
Yin, B1
Gu, G1
Chai, M1
Heo, DN1
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Clinical Trials (19)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating the Expression Levels of microRNA-10b in Patients With Gliomas[NCT01849952]200 participants (Anticipated)Observational2020-02-28Recruiting
PHASE I, OPEN LABEL, MULTICENTER DOSE ESCALATION STUDY OF GLIADEL IN PATIENTS WITH RECURRENT MALIGNANT GLIOMA[NCT00004028]Phase 10 participants Interventional1996-09-30Completed
A Phase II Trial of Temozolomide and BCNU for Anaplastic Gliomas[NCT00003176]Phase 282 participants Interventional1998-03-25Completed
A Phase 2a Study of the Addition of Temozolomide to a Standard Conditioning Regimen for Autologous Stem Cell Transplantation in Relapsed and Refractory Central Nervous System (CNS) Lymphoma[NCT01235793]Phase 211 participants (Actual)Interventional2010-10-14Terminated (stopped due to The clinical trial was terminated due to poor enrollment)
A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas[NCT00881595]Phase 20 participants (Actual)Interventional2009-02-28Withdrawn (stopped due to No patients accrued since study opened)
Chemo Sensitization Before Hematopoietic Stem Cell Transplantation With a CXCR4 Antagonist in Patients With Acute Leukemia in Complete Remission: Pilot Study[NCT02605460]Phase 220 participants (Anticipated)Interventional2014-02-28Recruiting
Phase I GLIADEL and Continuous Infusion of Intravenous O6-Benzylguanine Trial in Patients With Recurrent Malignant Glioma[NCT00004892]Phase 10 participants Interventional2000-04-30Completed
(Cost)Effectiveness of MR-guided LITT Therapy in Patients With Primary Irresectable Glioblastoma: a Prospective Multicenter Randomized Controlled Trial (EMITT)[NCT05318612]Phase 3238 participants (Anticipated)Interventional2022-04-08Recruiting
A Family Study of Adults With Glioma[NCT00339352]1,871 participants (Actual)Observational1999-03-11Completed
EUS-Guided Radiofrequency Ablation of Pancreatic Cysts - A Safety and Efficacy Trial[NCT05916846]28 participants (Anticipated)Interventional2023-04-24Recruiting
EFFECT OF DIBROMODULCITOL PLUS BCNU ON FREE INTERVAL AND SURVIVAL OF PATIENTS WITH SUPRATENTORIAL MALIGNANT BRAIN GLIOMAS, A PHASE III TYPE STUDY[NCT00002620]Phase 3212 participants (Anticipated)Interventional1994-11-30Completed
A Phase II Study of Peg-Interferon Alpha-2B (Peg-Intron(TM)) and Thalidomide in Adults With Recurrent High-Grade Gliomas[NCT00047879]Phase 27 participants (Actual)Interventional2002-10-31Completed
Phase II, Single Arm, Open Label Clinical Trial With Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas[NCT01574092]Phase 239 participants (Actual)Interventional2009-11-30Completed
Development of Quantitative Imaging Biomarkers for Evaluating Sarcoma Patients[NCT02579980]32 participants (Actual)Interventional2015-10-31Completed
Phase I Trial of AZD8055, An Oral MTOR Kinase Inhibitor, for Adults With Recurrent Gliomas[NCT01316809]Phase 122 participants (Actual)Interventional2011-03-04Completed
(11C)N-Desmethyl-Loperamide as a Marker of P-Glycoprotein Function in Patients With Gliomas[NCT01281982]2 participants (Actual)Observational2011-01-13Terminated
Phase I Trial of AZD7451, A Topomysin-Receptor Kinase (TRK) Inhibitor, For Adults With Recurrent Glioblastoma Multiforme (GBM)[NCT01468324]Phase 114 participants (Actual)Interventional2011-10-05Completed
A Phase I/II Study of the Safety and Feasibility of Administering T Cells Expressing Anti-EGFRvIII Chimeric Antigen Receptor to Patients With Malignant Gliomas Expressing EGFRvIII[NCT01454596]Phase 1/Phase 218 participants (Actual)Interventional2012-05-16Completed
Does Varenicline Influence Alcohol Consumption in Alcohol Dependent Individuals?[NCT00846859]Phase 2162 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Safest Dose of Temozolomide for the DRBEAT Regimen

Safety will be assessed using a dose escalation design for temozolomide's use to determine the target dose and also to evaluate any and all acute treatment related toxicities. During the course of patient follow up and therapy, toxicities will be evaluated, particularly as the investigators will be determining the target dose of temozolomide. One of the major criteria for dose limiting toxicity for the study will be any Grade 3 or 4 nonhematologic toxicity from a list of commonly expected toxicities associated with autologous transplantation and temozolomide. (NCT01235793)
Timeframe: One Year

Interventiondose in mg/m^2 (Number)
DRBEAT Regimen773.25

One-year Progression-free Survival and Overall Survival

"Efficacy of the DRBEAT Regimen will be assessed by analysis of~one-year progression-free survival (PFS), defined as the time interval from maximal response from therapy to tumor regrowth, progression*, or death, (*Progression is defined as meeting the response criteria listed in Table 4: Response Criteria for Primary Central Nervous System Lymphoma according to Abrey LE, Batchelor TT, Ferreri AJM et al.)~and~Overall survival, defined as the time interval between the date of transplant and the date of death from any cause." (NCT01235793)
Timeframe: (1) One Year (2) Until date of death from any cause, assessed up to 2 years

InterventionDays (Median)
Progression Free SurvivalOverall Survival
DRBEAT Regimen132564

The Number of Participants With Adverse Events

Here are the total number of participants with adverse events. For the detailed list of adverse events see the adverse event module. (NCT00047879)
Timeframe: 4 months

InterventionParticipants (Number)
Glioblastoma Multiforme Stratum4
Anaplastic Glioma Stratum2

Circulating Chimeric Antigen Receptor (CAR+) Cells in Peripheral Blood at 1 Month Post Treatment

CAR and vector presence were quantitated in peripheral blood mononuclear cell (PBMC) samples using established polymerase chain reaction (PCR) techniques (NCT01454596)
Timeframe: 1 month post transplant

InterventionK/µL (Median)
Group A (Steroids) - Cohort 1: 1x10(7)23
Group A (Steroids) - Cohort 2: 3x10(7)70
Group A (Steroids) - Cohort 3: 1x10(8)36
Group B (No Steroids) - Cohort 1: 1x10(7)67
Group B (No Steroids) - Cohort 2: 3x10(7)7
Group B (No Steroids) - Cohort 3: 1x10(8)43
Group B (No Steroids) - Cohort 4: 3x10(8)28
Group B (No Steroids) - Cohort 5: 1x10(9)25
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)12
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)67.5
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)NA
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)8

Number of Participants With Serious and Non-serious Adverse Events Assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0)

Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT01454596)
Timeframe: 51 dys Grp A, Cohort 1; Cohort 2:68 dys; Cohort 3:40 dys; Grp B, Cohort 1:67 dys; Cohort 2:48 dys; Cohort 3:55 dys; Cohort 4: 46 dys; Cohort 5:147 dys; C. Ster/No Ster Grp, Cohort 6:12 mos, 26 dys; Cohort 7:11 mos, 18 dys; Cohort 8:7 dys; Cohort 9:70 dys.

InterventionParticipants (Count of Participants)
Group A (Steroids) - Cohort 1: 1x10(7)1
Group A (Steroids) - Cohort 2: 3x10(7)1
Group A (Steroids) - Cohort 3: 1x10(8)1
Group B (No Steroids) - Cohort 1: 1x10(7)1
Group B (No Steroids) - Cohort 2: 3x10(7)1
Group B (No Steroids) - Cohort 3: 1x10(8)1
Group B (No Steroids) - Cohort 4: 3x10(8)1
Group B (No Steroids) - Cohort 5: 1x10(9)3
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)3
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)3
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)1
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)1

Number of Patients With an Objective Response

Objective response was assessed by comparison with baseline dynamic contrast enhanced magnetic resonance imaging with perfusion using Neuro-oncology Working Group proposed guidelines. Complete Response is disappearance of all measurable and non-measurable disease for at least 4 weeks. Partial Response is >/= 50% decrease in lesions for at least 4 weeks. Stable Disease does not meet the criteria for complete response, partial response or progression and requires stable lesions compared with baseline. Progression is >/= 25% increase in lesions. (NCT01454596)
Timeframe: 4 weeks after cell infusion and monthly as feasible up to 12 months

InterventionParticipants (Count of Participants)
Group A (Steroids) - Cohort 1: 1x10(7)0
Group A (Steroids) - Cohort 2: 3x10(7)0
Group A (Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 1: 1x10(7)0
Group B (No Steroids) - Cohort 2: 3x10(7)0
Group B (No Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 4: 3x10(8)0
Group B (No Steroids) - Cohort 5: 1x10(9)0
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)0
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)0
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)0
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)0

Number of Treatment Related Adverse Events

Aggregate of all adverse events ≥Grade 3 that are possibly, probably, and definitely related to treatment. Adverse events were assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). Per CTCAE, Grade 3 adverse events are severe, Grade 4 is life threatening, and Grade 5 is death. (NCT01454596)
Timeframe: From 4 weeks after cell infusion up to 77 days

Interventionadverse events (Number)
Group A (Steroids) - Cohort 1: 1x10(7)0
Group A (Steroids) - Cohort 2: 3x10(7)0
Group A (Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 1: 1x10(7)0
Group B (No Steroids) - Cohort 2: 3x10(7)0
Group B (No Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 4: 3x10(8)0
Group B (No Steroids) - Cohort 5: 1x10(9)0
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)0
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)0
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)1
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)1

Progression Free Survival

Progression was assessed by the Response Assessment in Neuro-Oncology (RANO) criteria and is defined as the circumstance when the magnetic resonance imaging (MRI) scan is ranked -2 (definitely worse) or -3 (development of a new lesion). (NCT01454596)
Timeframe: Time from the date of registration to the date of first observation of progressive disease up to 6 months after end of treatment

Interventionmonths (Median)
Group A (Steroids) - Cohort 1: 1x10(7)1.1
Group A (Steroids) - Cohort 2: 3x10(7)1.1
Group A (Steroids) - Cohort 3: 1x10(8)1.3
Group B (No Steroids) - Cohort 1: 1x10(7)1.9
Group B (No Steroids) - Cohort 2: 3x10(7)2.0
Group B (No Steroids) - Cohort 3: 1x10(8)1.5
Group B (No Steroids) - Cohort 4: 3x10(8)1.2
Group B (No Steroids) - Cohort 5: 1x10(9)1.1
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)2.7
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)1.1
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)0
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)2.0

Reviews

59 reviews available for carmustine and Glioma

ArticleYear
Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
    Neuro-Chirurgie, 2017, Volume: 63, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
    Neuro-Chirurgie, 2017, Volume: 63, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
    Neuro-Chirurgie, 2017, Volume: 63, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

2013
The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

2013
The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

2013
Current status of local therapy in malignant gliomas--a clinical review of three selected approaches.
    Pharmacology & therapeutics, 2013, Volume: 139, Issue:3

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as

2013
Current status of local therapy in malignant gliomas--a clinical review of three selected approaches.
    Pharmacology & therapeutics, 2013, Volume: 139, Issue:3

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as

2013
Current status of local therapy in malignant gliomas--a clinical review of three selected approaches.
    Pharmacology & therapeutics, 2013, Volume: 139, Issue:3

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as

2013
[II. Current status of BCNU stent in the brain for treatment of glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6

    Topics: Animals; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Decanoic Acids; Drug-Eluting Stents;

2013
[II. Current status of BCNU stent in the brain for treatment of glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6

    Topics: Animals; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Decanoic Acids; Drug-Eluting Stents;

2013
[II. Current status of BCNU stent in the brain for treatment of glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6

    Topics: Animals; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Decanoic Acids; Drug-Eluting Stents;

2013
Modeling mass transfer from carmustine-loaded polymeric implants for malignant gliomas.
    Journal of laboratory automation, 2014, Volume: 19, Issue:1

    Topics: Animals; Carmustine; Glioma; Humans; Infusion Pumps, Implantable; Models, Theoretical

2014
Modeling mass transfer from carmustine-loaded polymeric implants for malignant gliomas.
    Journal of laboratory automation, 2014, Volume: 19, Issue:1

    Topics: Animals; Carmustine; Glioma; Humans; Infusion Pumps, Implantable; Models, Theoretical

2014
Modeling mass transfer from carmustine-loaded polymeric implants for malignant gliomas.
    Journal of laboratory automation, 2014, Volume: 19, Issue:1

    Topics: Animals; Carmustine; Glioma; Humans; Infusion Pumps, Implantable; Models, Theoretical

2014
The role of Gliadel wafers in the treatment of high-grade gliomas.
    Expert review of anticancer therapy, 2013, Volume: 13, Issue:12

    Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Glioblastoma; Glioma; Humans; Middle Aged; Polyesters

2013
The role of Gliadel wafers in the treatment of high-grade gliomas.
    Expert review of anticancer therapy, 2013, Volume: 13, Issue:12

    Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Glioblastoma; Glioma; Humans; Middle Aged; Polyesters

2013
The role of Gliadel wafers in the treatment of high-grade gliomas.
    Expert review of anticancer therapy, 2013, Volume: 13, Issue:12

    Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Glioblastoma; Glioma; Humans; Middle Aged; Polyesters

2013
Combining microbubbles and ultrasound for drug delivery to brain tumors: current progress and overview.
    Theranostics, 2014, Volume: 4, Issue:4

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Contrast Media; Drug Delivery Systems; Glioma; Hum

2014
Combining microbubbles and ultrasound for drug delivery to brain tumors: current progress and overview.
    Theranostics, 2014, Volume: 4, Issue:4

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Contrast Media; Drug Delivery Systems; Glioma; Hum

2014
Combining microbubbles and ultrasound for drug delivery to brain tumors: current progress and overview.
    Theranostics, 2014, Volume: 4, Issue:4

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Contrast Media; Drug Delivery Systems; Glioma; Hum

2014
Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Drug Implants; Gliom

2015
Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Drug Implants; Gliom

2015
Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Drug Implants; Gliom

2015
Advanced interstitial chemotherapy for treating malignant glioma.
    Expert opinion on drug delivery, 2016, Volume: 13, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Decanoic

2016
Advanced interstitial chemotherapy for treating malignant glioma.
    Expert opinion on drug delivery, 2016, Volume: 13, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Decanoic

2016
Advanced interstitial chemotherapy for treating malignant glioma.
    Expert opinion on drug delivery, 2016, Volume: 13, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Decanoic

2016
Chemotherapeutic wafers for High Grade Glioma.
    The Cochrane database of systematic reviews, 2008, Jul-16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; H

2008
Chemotherapeutic wafers for High Grade Glioma.
    The Cochrane database of systematic reviews, 2008, Jul-16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; H

2008
Chemotherapeutic wafers for High Grade Glioma.
    The Cochrane database of systematic reviews, 2008, Jul-16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; H

2008
What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Disease Models, Animal; Drug Evaluation; Gli

2009
What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Disease Models, Animal; Drug Evaluation; Gli

2009
What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Disease Models, Animal; Drug Evaluation; Gli

2009
Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience.
    Current medical research and opinion, 2008, Volume: 24, Issue:11

    Topics: Absorbable Implants; Administration, Topical; Algorithms; Antineoplastic Agents, Alkylating; Brain N

2008
Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience.
    Current medical research and opinion, 2008, Volume: 24, Issue:11

    Topics: Absorbable Implants; Administration, Topical; Algorithms; Antineoplastic Agents, Alkylating; Brain N

2008
Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience.
    Current medical research and opinion, 2008, Volume: 24, Issue:11

    Topics: Absorbable Implants; Administration, Topical; Algorithms; Antineoplastic Agents, Alkylating; Brain N

2008
Localized BCNU chemotherapy and the multimodal management of malignant glioma.
    Current medical research and opinion, 2009, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Glioma; Humans; Prognosis

2009
Localized BCNU chemotherapy and the multimodal management of malignant glioma.
    Current medical research and opinion, 2009, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Glioma; Humans; Prognosis

2009
Localized BCNU chemotherapy and the multimodal management of malignant glioma.
    Current medical research and opinion, 2009, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Glioma; Humans; Prognosis

2009
Crossing borders: surgically mediated drug delivery techniques.
    Clinical neurosurgery, 2008, Volume: 55

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bacterial Toxins; Biological Availability; Brain Neop

2008
Crossing borders: surgically mediated drug delivery techniques.
    Clinical neurosurgery, 2008, Volume: 55

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bacterial Toxins; Biological Availability; Brain Neop

2008
Crossing borders: surgically mediated drug delivery techniques.
    Clinical neurosurgery, 2008, Volume: 55

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bacterial Toxins; Biological Availability; Brain Neop

2008
Risk management in the treatment of malignant gliomas with BCNU wafer implants.
    Central European neurosurgery, 2010, Volume: 71, Issue:4

    Topics: Absorbable Implants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modali

2010
Risk management in the treatment of malignant gliomas with BCNU wafer implants.
    Central European neurosurgery, 2010, Volume: 71, Issue:4

    Topics: Absorbable Implants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modali

2010
Risk management in the treatment of malignant gliomas with BCNU wafer implants.
    Central European neurosurgery, 2010, Volume: 71, Issue:4

    Topics: Absorbable Implants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modali

2010
[Chemotherapeutic wafers in treatment of malignant cerebral glioma. Assessment of a Cochrane review].
    Ugeskrift for laeger, 2010, Jan-18, Volume: 172, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Evidence-Based Medici

2010
[Chemotherapeutic wafers in treatment of malignant cerebral glioma. Assessment of a Cochrane review].
    Ugeskrift for laeger, 2010, Jan-18, Volume: 172, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Evidence-Based Medici

2010
[Chemotherapeutic wafers in treatment of malignant cerebral glioma. Assessment of a Cochrane review].
    Ugeskrift for laeger, 2010, Jan-18, Volume: 172, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Evidence-Based Medici

2010
Chemotherapy wafers for high grade glioma.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Decanoic

2011
Chemotherapy wafers for high grade glioma.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Decanoic

2011
Chemotherapy wafers for high grade glioma.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Decanoic

2011
The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Delayed-Action Prepa

2012
The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Delayed-Action Prepa

2012
The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Delayed-Action Prepa

2012
[Evidence-based radiation therapy for primary brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Evidence-Based Medicine; Glioma; Hum

2003
[Evidence-based radiation therapy for primary brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Evidence-Based Medicine; Glioma; Hum

2003
[Evidence-based radiation therapy for primary brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Evidence-Based Medicine; Glioma; Hum

2003
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic

2003
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic

2003
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic

2003
Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers.
    Investigational new drugs, 2004, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; D

2004
Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers.
    Investigational new drugs, 2004, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; D

2004
Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers.
    Investigational new drugs, 2004, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; D

2004
The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma.
    International journal of radiation oncology, biology, physics, 2005, Sep-01, Volume: 63, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cr

2005
The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma.
    International journal of radiation oncology, biology, physics, 2005, Sep-01, Volume: 63, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cr

2005
The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma.
    International journal of radiation oncology, biology, physics, 2005, Sep-01, Volume: 63, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cr

2005
Local treatment of malignant brain tumors using implantable chemotherapeutic polymers.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2005, Volume: 3, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biocompatible Materials; Biodegradation, E

2005
Local treatment of malignant brain tumors using implantable chemotherapeutic polymers.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2005, Volume: 3, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biocompatible Materials; Biodegradation, E

2005
Local treatment of malignant brain tumors using implantable chemotherapeutic polymers.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2005, Volume: 3, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biocompatible Materials; Biodegradation, E

2005
[Treatment for malignant glioma].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
[Treatment for malignant glioma].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
[Treatment for malignant glioma].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Central Nervous System Neoplasms; Decanoic A

2007
Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Central Nervous System Neoplasms; Decanoic A

2007
Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Central Nervous System Neoplasms; Decanoic A

2007
The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:45

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2007
The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:45

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2007
The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:45

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2007
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dac

2008
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dac

2008
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dac

2008
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barr

2007
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barr

2007
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barr

2007
High dose chemotherapy with autologous bone marrow rescue for high grade gliomas of the brain: a potential for improvement in therapeutic results.
    Neurosurgery, 1984, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carmus

1984
High dose chemotherapy with autologous bone marrow rescue for high grade gliomas of the brain: a potential for improvement in therapeutic results.
    Neurosurgery, 1984, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carmus

1984
High dose chemotherapy with autologous bone marrow rescue for high grade gliomas of the brain: a potential for improvement in therapeutic results.
    Neurosurgery, 1984, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carmus

1984
Clonal tumor cell heterogeneity.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Brain Neoplasms; Carmustine; Chromosome Aberrations; Cisplatin; Culture Techniques; Drug Resistance;

1984
Clonal tumor cell heterogeneity.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Brain Neoplasms; Carmustine; Chromosome Aberrations; Cisplatin; Culture Techniques; Drug Resistance;

1984
Clonal tumor cell heterogeneity.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Brain Neoplasms; Carmustine; Chromosome Aberrations; Cisplatin; Culture Techniques; Drug Resistance;

1984
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms;

1982
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms;

1982
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms;

1982
[Colony forming efficiency assay and human tumor (author's transl)].
    No shinkei geka. Neurological surgery, 1981, Volume: 9, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Gl

1981
[Colony forming efficiency assay and human tumor (author's transl)].
    No shinkei geka. Neurological surgery, 1981, Volume: 9, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Gl

1981
[Colony forming efficiency assay and human tumor (author's transl)].
    No shinkei geka. Neurological surgery, 1981, Volume: 9, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Gl

1981
Malignant gliomas in older adults with poor prognostic signs. Getting nowhere, and taking a long time to do it.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine

1995
Malignant gliomas in older adults with poor prognostic signs. Getting nowhere, and taking a long time to do it.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine

1995
Malignant gliomas in older adults with poor prognostic signs. Getting nowhere, and taking a long time to do it.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine

1995
[Chemotherapy of brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy;

1994
[Chemotherapy of brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy;

1994
[Chemotherapy of brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy;

1994
Interstitial chemotherapy with sustained-release polymer systems for the treatment of malignant gliomas.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1994, Volume: 135

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Brain Neoplasms; Carmustine; Chemotherapy,

1994
Interstitial chemotherapy with sustained-release polymer systems for the treatment of malignant gliomas.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1994, Volume: 135

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Brain Neoplasms; Carmustine; Chemotherapy,

1994
Interstitial chemotherapy with sustained-release polymer systems for the treatment of malignant gliomas.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1994, Volume: 135

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Brain Neoplasms; Carmustine; Chemotherapy,

1994
The role of interstitial BCNU chemotherapy in the treatment of malignant glioma.
    Surgical neurology, 2000, Volume: 53, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine; Cl

2000
The role of interstitial BCNU chemotherapy in the treatment of malignant glioma.
    Surgical neurology, 2000, Volume: 53, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine; Cl

2000
The role of interstitial BCNU chemotherapy in the treatment of malignant glioma.
    Surgical neurology, 2000, Volume: 53, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine; Cl

2000
High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults.
    Cancer investigation, 2001, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Chemotherapy

2001
High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults.
    Cancer investigation, 2001, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Chemotherapy

2001
High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults.
    Cancer investigation, 2001, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Chemotherapy

2001
Temozolomide in combination with other cytotoxic agents.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carmustine; Central Nervous System Neo

2001
Temozolomide in combination with other cytotoxic agents.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carmustine; Central Nervous System Neo

2001
Temozolomide in combination with other cytotoxic agents.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carmustine; Central Nervous System Neo

2001
[Role of high-dose chemotherapy with hemopoietic stem-cell support in the treatment of adult patients with high-grade glioma].
    Bulletin du cancer, 2001, Volume: 88, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; C

2001
[Role of high-dose chemotherapy with hemopoietic stem-cell support in the treatment of adult patients with high-grade glioma].
    Bulletin du cancer, 2001, Volume: 88, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; C

2001
[Role of high-dose chemotherapy with hemopoietic stem-cell support in the treatment of adult patients with high-grade glioma].
    Bulletin du cancer, 2001, Volume: 88, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; C

2001
Multimodality program involving stereotactic surgery in brain tumor management.
    Stereotactic and functional neurosurgery, 2000, Volume: 75, Issue:2-3

    Topics: Adult; Antineoplastic Agents; Biopsy; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality

2000
Multimodality program involving stereotactic surgery in brain tumor management.
    Stereotactic and functional neurosurgery, 2000, Volume: 75, Issue:2-3

    Topics: Adult; Antineoplastic Agents; Biopsy; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality

2000
Multimodality program involving stereotactic surgery in brain tumor management.
    Stereotactic and functional neurosurgery, 2000, Volume: 75, Issue:2-3

    Topics: Adult; Antineoplastic Agents; Biopsy; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality

2000
Drug delivery to tumors of the central nervous system.
    Current neurology and neuroscience reports, 2001, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Biodegradation, Environmental; Blood-Brain Barrier; Brain Neoplasms; Carmusti

2001
Drug delivery to tumors of the central nervous system.
    Current neurology and neuroscience reports, 2001, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Biodegradation, Environmental; Blood-Brain Barrier; Brain Neoplasms; Carmusti

2001
Drug delivery to tumors of the central nervous system.
    Current neurology and neuroscience reports, 2001, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Biodegradation, Environmental; Blood-Brain Barrier; Brain Neoplasms; Carmusti

2001
Pharmacokinetics of the carmustine implant.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Comput

2002
Pharmacokinetics of the carmustine implant.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Comput

2002
Pharmacokinetics of the carmustine implant.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Comput

2002
NO-mediated chemoresistance in C6 glioma cells.
    Annals of the New York Academy of Sciences, 2002, Volume: 962

    Topics: Animals; Carmustine; DNA-Binding Proteins; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Humans;

2002
NO-mediated chemoresistance in C6 glioma cells.
    Annals of the New York Academy of Sciences, 2002, Volume: 962

    Topics: Animals; Carmustine; DNA-Binding Proteins; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Humans;

2002
NO-mediated chemoresistance in C6 glioma cells.
    Annals of the New York Academy of Sciences, 2002, Volume: 962

    Topics: Animals; Carmustine; DNA-Binding Proteins; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Humans;

2002
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Combined modality therapy for intracranial tumors.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Child; Cranioph

1975
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis

1977
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis

1977
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis

1977
Chemotherapy: the agents in current use.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma;

1975
Chemotherapy: the agents in current use.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma;

1975
Chemotherapy: the agents in current use.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma;

1975
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Mod

1992
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Mod

1992
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Mod

1992
Biology and therapy of glial tumors.
    Current opinion in neurology and neurosurgery, 1992, Volume: 5, Issue:6

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Cell Division; Cell Surviva

1992
Biology and therapy of glial tumors.
    Current opinion in neurology and neurosurgery, 1992, Volume: 5, Issue:6

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Cell Division; Cell Surviva

1992
Biology and therapy of glial tumors.
    Current opinion in neurology and neurosurgery, 1992, Volume: 5, Issue:6

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Cell Division; Cell Surviva

1992
Tumor heterogeneity and intrinsically chemoresistant subpopulations in freshly resected human malignant gliomas.
    Basic life sciences, 1991, Volume: 57

    Topics: Aneuploidy; Antineoplastic Agents; Brain Neoplasms; Carmustine; Clone Cells; Drug Resistance; Geneti

1991
Tumor heterogeneity and intrinsically chemoresistant subpopulations in freshly resected human malignant gliomas.
    Basic life sciences, 1991, Volume: 57

    Topics: Aneuploidy; Antineoplastic Agents; Brain Neoplasms; Carmustine; Clone Cells; Drug Resistance; Geneti

1991
Tumor heterogeneity and intrinsically chemoresistant subpopulations in freshly resected human malignant gliomas.
    Basic life sciences, 1991, Volume: 57

    Topics: Aneuploidy; Antineoplastic Agents; Brain Neoplasms; Carmustine; Clone Cells; Drug Resistance; Geneti

1991
Brain tumors.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Carmustine; Child; Combined Modality Therapy; Glioma;

1991
Brain tumors.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Carmustine; Child; Combined Modality Therapy; Glioma;

1991
Brain tumors.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Carmustine; Child; Combined Modality Therapy; Glioma;

1991
The subpopulations and isolated cell types of freshly resected high grade human gliomas: their influence on the tumor's evolution in vivo and behavior and therapy in vitro.
    Cancer metastasis reviews, 1985, Volume: 4, Issue:2

    Topics: Carmustine; Cell Line; Cells, Cultured; Chromosome Banding; Clone Cells; Genetic Variation; Glioblas

1985
The subpopulations and isolated cell types of freshly resected high grade human gliomas: their influence on the tumor's evolution in vivo and behavior and therapy in vitro.
    Cancer metastasis reviews, 1985, Volume: 4, Issue:2

    Topics: Carmustine; Cell Line; Cells, Cultured; Chromosome Banding; Clone Cells; Genetic Variation; Glioblas

1985
The subpopulations and isolated cell types of freshly resected high grade human gliomas: their influence on the tumor's evolution in vivo and behavior and therapy in vitro.
    Cancer metastasis reviews, 1985, Volume: 4, Issue:2

    Topics: Carmustine; Cell Line; Cells, Cultured; Chromosome Banding; Clone Cells; Genetic Variation; Glioblas

1985
High dose chemotherapy in solid tumours in adults.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marr

1986
High dose chemotherapy in solid tumours in adults.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marr

1986
High dose chemotherapy in solid tumours in adults.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marr

1986
Brain tumors.
    Cancer chemotherapy and biological response modifiers, 1987, Volume: 9

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Child; Glioma; Humans; Infusions, Intra-Arterial

1987
Brain tumors.
    Cancer chemotherapy and biological response modifiers, 1987, Volume: 9

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Child; Glioma; Humans; Infusions, Intra-Arterial

1987
Brain tumors.
    Cancer chemotherapy and biological response modifiers, 1987, Volume: 9

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Child; Glioma; Humans; Infusions, Intra-Arterial

1987
Principles of brain tumor chemotherapy.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1986
Principles of brain tumor chemotherapy.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1986
Principles of brain tumor chemotherapy.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1986
Recent and current investigations of radiation therapy of malignant gliomas.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperb

1986
Recent and current investigations of radiation therapy of malignant gliomas.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperb

1986
Recent and current investigations of radiation therapy of malignant gliomas.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperb

1986
In vitro drug sensitivity testing in human gliomas.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cells, Cultured; Drug Evaluation, Preclinical; G

1987
In vitro drug sensitivity testing in human gliomas.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cells, Cultured; Drug Evaluation, Preclinical; G

1987
In vitro drug sensitivity testing in human gliomas.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cells, Cultured; Drug Evaluation, Preclinical; G

1987
Proceedings: Chemotherapy of malignant glioma.
    Proceedings. National Cancer Conference, 1972, Volume: 7

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Evaluation Studies as Topic

1972
Proceedings: Chemotherapy of malignant glioma.
    Proceedings. National Cancer Conference, 1972, Volume: 7

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Evaluation Studies as Topic

1972
Proceedings: Chemotherapy of malignant glioma.
    Proceedings. National Cancer Conference, 1972, Volume: 7

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Evaluation Studies as Topic

1972
[Chemotherapy of brain neoplasms in children].
    Zeitschrift fur Allgemeinmedizin, 1974, Sep-10, Volume: 50, Issue:25

    Topics: Age Factors; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Child; Cyclophosphamide;

1974
[Chemotherapy of brain neoplasms in children].
    Zeitschrift fur Allgemeinmedizin, 1974, Sep-10, Volume: 50, Issue:25

    Topics: Age Factors; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Child; Cyclophosphamide;

1974
[Chemotherapy of brain neoplasms in children].
    Zeitschrift fur Allgemeinmedizin, 1974, Sep-10, Volume: 50, Issue:25

    Topics: Age Factors; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Child; Cyclophosphamide;

1974
Nitrosoureas in central nervous system tumors.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclohexanes; Glioma; Humans; Injections, Intrav

1973
Nitrosoureas in central nervous system tumors.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclohexanes; Glioma; Humans; Injections, Intrav

1973
Nitrosoureas in central nervous system tumors.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclohexanes; Glioma; Humans; Injections, Intrav

1973

Trials

96 trials available for carmustine and Glioma

ArticleYear
A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 74

    Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Carmustine

2020
A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 74

    Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Carmustine

2020
A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 74

    Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Carmustine

2020
NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2018
NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2018
NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2018
A multicenter phase I/II study of the BCNU implant (Gliadel(®) Wafer) for Japanese patients with malignant gliomas.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2014
A multicenter phase I/II study of the BCNU implant (Gliadel(®) Wafer) for Japanese patients with malignant gliomas.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2014
A multicenter phase I/II study of the BCNU implant (Gliadel(®) Wafer) for Japanese patients with malignant gliomas.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2014
Safety evaluation of high-dose BCNU-loaded biodegradable implants in Chinese patients with recurrent malignant gliomas.
    Journal of the neurological sciences, 2014, Aug-15, Volume: 343, Issue:1-2

    Topics: Absorbable Implants; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain

2014
Safety evaluation of high-dose BCNU-loaded biodegradable implants in Chinese patients with recurrent malignant gliomas.
    Journal of the neurological sciences, 2014, Aug-15, Volume: 343, Issue:1-2

    Topics: Absorbable Implants; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain

2014
Safety evaluation of high-dose BCNU-loaded biodegradable implants in Chinese patients with recurrent malignant gliomas.
    Journal of the neurological sciences, 2014, Aug-15, Volume: 343, Issue:1-2

    Topics: Absorbable Implants; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain

2014
BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2015
BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2015
BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2015
External beam irradiation and the combination of cisplatin and carmustine followed by carmustine alone for the treatment of high-grade glioma: a phase 2 Southwest Oncology Group trial.
    Cancer, 2008, Aug-01, Volume: 113, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2008
External beam irradiation and the combination of cisplatin and carmustine followed by carmustine alone for the treatment of high-grade glioma: a phase 2 Southwest Oncology Group trial.
    Cancer, 2008, Aug-01, Volume: 113, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2008
External beam irradiation and the combination of cisplatin and carmustine followed by carmustine alone for the treatment of high-grade glioma: a phase 2 Southwest Oncology Group trial.
    Cancer, 2008, Aug-01, Volume: 113, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2008
Phase II trial of intratumoral BCNU injection and radiotherapy on untreated adult malignant glioma.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Mapping; Brain Neoplasms; Carmustine; Cerebrovascular

2010
Phase II trial of intratumoral BCNU injection and radiotherapy on untreated adult malignant glioma.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Mapping; Brain Neoplasms; Carmustine; Cerebrovascular

2010
Phase II trial of intratumoral BCNU injection and radiotherapy on untreated adult malignant glioma.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Mapping; Brain Neoplasms; Carmustine; Cerebrovascular

2010
The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series.
    Acta neurochirurgica, 2010, Volume: 152, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans;

2010
The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series.
    Acta neurochirurgica, 2010, Volume: 152, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans;

2010
The first 3 months after BCNU wafers implantation in high-grade glioma patients: clinical and radiological considerations on a clinical series.
    Acta neurochirurgica, 2010, Volume: 152, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans;

2010
Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis.
    Journal of neurosurgical sciences, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biocompatible Materials; Carmustine; Combined Modali

2011
Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis.
    Journal of neurosurgical sciences, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biocompatible Materials; Carmustine; Combined Modali

2011
Safety and feasibility of the adjunct of local chemotherapy with biodegradable carmustine (BCNU) wafers to the standard multimodal approach to high grade gliomas at first diagnosis.
    Journal of neurosurgical sciences, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biocompatible Materials; Carmustine; Combined Modali

2011
Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials, Ph

2011
Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials, Ph

2011
Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials, Ph

2011
Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine.
    Neurosurgery, 2002, Volume: 51, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality The

2002
The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine.
    Neurosurgery, 2002, Volume: 51, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality The

2002
The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine.
    Neurosurgery, 2002, Volume: 51, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality The

2002
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.
    Neuro-oncology, 2003, Volume: 5, Issue:2

    Topics: Adult; Aged; Biocompatible Materials; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Doub

2003
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.
    Neuro-oncology, 2003, Volume: 5, Issue:2

    Topics: Adult; Aged; Biocompatible Materials; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Doub

2003
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.
    Neuro-oncology, 2003, Volume: 5, Issue:2

    Topics: Adult; Aged; Biocompatible Materials; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Doub

2003
The surgical bed after BCNU polymer wafer placement for recurrent glioma: serial assessment on CT and MR imaging.
    AJR. American journal of roentgenology, 2003, Volume: 180, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Administration Rou

2003
The surgical bed after BCNU polymer wafer placement for recurrent glioma: serial assessment on CT and MR imaging.
    AJR. American journal of roentgenology, 2003, Volume: 180, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Administration Rou

2003
The surgical bed after BCNU polymer wafer placement for recurrent glioma: serial assessment on CT and MR imaging.
    AJR. American journal of roentgenology, 2003, Volume: 180, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Administration Rou

2003
Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-01, Volume: 21, Issue:9

    Topics: Absorbable Implants; Adult; Aged; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain

2003
Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-01, Volume: 21, Issue:9

    Topics: Absorbable Implants; Adult; Aged; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain

2003
Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-01, Volume: 21, Issue:9

    Topics: Absorbable Implants; Adult; Aged; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain

2003
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jun-15, Volume: 21, Issue:12

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2003
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jun-15, Volume: 21, Issue:12

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2003
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jun-15, Volume: 21, Issue:12

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2003
A single prior course of BCNU-cisplatin chemotherapy has a significant deleterious effect on mobilization kinetics of otherwise untreated patients.
    Bone marrow transplantation, 2004, Volume: 33, Issue:5

    Topics: Adult; Antigens, CD34; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Ca

2004
A single prior course of BCNU-cisplatin chemotherapy has a significant deleterious effect on mobilization kinetics of otherwise untreated patients.
    Bone marrow transplantation, 2004, Volume: 33, Issue:5

    Topics: Adult; Antigens, CD34; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Ca

2004
A single prior course of BCNU-cisplatin chemotherapy has a significant deleterious effect on mobilization kinetics of otherwise untreated patients.
    Bone marrow transplantation, 2004, Volume: 33, Issue:5

    Topics: Adult; Antigens, CD34; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Ca

2004
Clinical course and pathologic findings after Gliadel and radiotherapy for newly diagnosed malignant glioma: implications for patient management.
    Cancer investigation, 2004, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2004
Clinical course and pathologic findings after Gliadel and radiotherapy for newly diagnosed malignant glioma: implications for patient management.
    Cancer investigation, 2004, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2004
Clinical course and pathologic findings after Gliadel and radiotherapy for newly diagnosed malignant glioma: implications for patient management.
    Cancer investigation, 2004, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2004
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2004
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2004
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2004
BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Pr

2004
BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Pr

2004
BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Pr

2004
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine;

2004
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine;

2004
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine;

2004
Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine;

2004
Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine;

2004
Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine;

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
[Effect of photodynamic therapy combined with interstitial chemotherapy for gliomas].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2005
[Effect of photodynamic therapy combined with interstitial chemotherapy for gliomas].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2005
[Effect of photodynamic therapy combined with interstitial chemotherapy for gliomas].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2005
Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.
    Acta neurochirurgica, 2006, Volume: 148, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Decanoic Acids;

2006
Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.
    Acta neurochirurgica, 2006, Volume: 148, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Decanoic Acids;

2006
Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.
    Acta neurochirurgica, 2006, Volume: 148, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Decanoic Acids;

2006
Outcome of children treated with preradiation chemotherapy for a high-grade glioma: results of a French Society of Pediatric Oncology (SFOP) Pilot Study.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvan

2007
Outcome of children treated with preradiation chemotherapy for a high-grade glioma: results of a French Society of Pediatric Oncology (SFOP) Pilot Study.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvan

2007
Outcome of children treated with preradiation chemotherapy for a high-grade glioma: results of a French Society of Pediatric Oncology (SFOP) Pilot Study.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvan

2007
Phase I trial of polifeprosan 20 with carmustine implant plus continuous infusion of intravenous O6-benzylguanine in adults with recurrent malignant glioma: new approaches to brain tumor therapy CNS consortium trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Feb-01, Volume: 25, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Phase I trial of polifeprosan 20 with carmustine implant plus continuous infusion of intravenous O6-benzylguanine in adults with recurrent malignant glioma: new approaches to brain tumor therapy CNS consortium trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Feb-01, Volume: 25, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Phase I trial of polifeprosan 20 with carmustine implant plus continuous infusion of intravenous O6-benzylguanine in adults with recurrent malignant glioma: new approaches to brain tumor therapy CNS consortium trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Feb-01, Volume: 25, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Bleomycin and brain tumors. A review.
    Journal of neuro-oncology, 1983, Volume: 1, Issue:3

    Topics: Adult; Aged; Animals; Bleomycin; Brain; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combi

1983
Bleomycin and brain tumors. A review.
    Journal of neuro-oncology, 1983, Volume: 1, Issue:3

    Topics: Adult; Aged; Animals; Bleomycin; Brain; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combi

1983
Bleomycin and brain tumors. A review.
    Journal of neuro-oncology, 1983, Volume: 1, Issue:3

    Topics: Adult; Aged; Animals; Bleomycin; Brain; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combi

1983
Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model.
    Journal of neurosurgery, 1981, Volume: 54, Issue:2

    Topics: Adjuvants, Immunologic; Alpharetrovirus; Animals; Brain Neoplasms; Carmustine; Clinical Trials as To

1981
Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model.
    Journal of neurosurgery, 1981, Volume: 54, Issue:2

    Topics: Adjuvants, Immunologic; Alpharetrovirus; Animals; Brain Neoplasms; Carmustine; Clinical Trials as To

1981
Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model.
    Journal of neurosurgery, 1981, Volume: 54, Issue:2

    Topics: Adjuvants, Immunologic; Alpharetrovirus; Animals; Brain Neoplasms; Carmustine; Clinical Trials as To

1981
Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma.
    Cancer treatment reports, 1983, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration

1983
Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma.
    Cancer treatment reports, 1983, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration

1983
Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma.
    Cancer treatment reports, 1983, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration

1983
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study.
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration

1983
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study.
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration

1983
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery; preliminary results of an RTOG study.
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration

1983
Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Adult; Age Factors; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials

1983
Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Adult; Age Factors; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials

1983
Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Adult; Age Factors; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials

1983
Perioperative carmustine chemotherapy for malignant brain tumors.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combine

1984
Perioperative carmustine chemotherapy for malignant brain tumors.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combine

1984
Perioperative carmustine chemotherapy for malignant brain tumors.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combine

1984
Intracarotid chemotherapy with a combination of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), cis-diaminedichloroplatinum (cisplatin), and 4'-O-demethyl-1-O-(4,6-O-2-thenylidene-beta-D-glucopyranosyl) epipodophyllotoxin (VM-26) in the treatment of primary
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1984
Intracarotid chemotherapy with a combination of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), cis-diaminedichloroplatinum (cisplatin), and 4'-O-demethyl-1-O-(4,6-O-2-thenylidene-beta-D-glucopyranosyl) epipodophyllotoxin (VM-26) in the treatment of primary
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1984
Intracarotid chemotherapy with a combination of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), cis-diaminedichloroplatinum (cisplatin), and 4'-O-demethyl-1-O-(4,6-O-2-thenylidene-beta-D-glucopyranosyl) epipodophyllotoxin (VM-26) in the treatment of primary
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1984
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms;

1982
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms;

1982
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms;

1982
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery.
    The New England journal of medicine, 1980, Dec-04, Volume: 303, Issue:23

    Topics: Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; H

1980
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery.
    The New England journal of medicine, 1980, Dec-04, Volume: 303, Issue:23

    Topics: Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; H

1980
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery.
    The New England journal of medicine, 1980, Dec-04, Volume: 303, Issue:23

    Topics: Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; H

1980
Primary intracranial gliomas: clinical studies and treatment regimens of the Brain Tumor Research Center, University of California, San Francisco, 1977-1979.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Antineoplastic Agents; Brain Neoplasms; California; Carmustine; Clinical Trials as Topic; Drug Thera

1981
Primary intracranial gliomas: clinical studies and treatment regimens of the Brain Tumor Research Center, University of California, San Francisco, 1977-1979.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Antineoplastic Agents; Brain Neoplasms; California; Carmustine; Clinical Trials as Topic; Drug Thera

1981
Primary intracranial gliomas: clinical studies and treatment regimens of the Brain Tumor Research Center, University of California, San Francisco, 1977-1979.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Antineoplastic Agents; Brain Neoplasms; California; Carmustine; Clinical Trials as Topic; Drug Thera

1981
Evaluating glioma therapies: modeling treatments and predicting outcomes.
    Journal of the National Cancer Institute, 1995, Dec-20, Volume: 87, Issue:24

    Topics: Adolescent; Adult; Aged; Brachytherapy; Brain Neoplasms; Carmustine; Child; Combined Modality Therap

1995
Evaluating glioma therapies: modeling treatments and predicting outcomes.
    Journal of the National Cancer Institute, 1995, Dec-20, Volume: 87, Issue:24

    Topics: Adolescent; Adult; Aged; Brachytherapy; Brain Neoplasms; Carmustine; Child; Combined Modality Therap

1995
Evaluating glioma therapies: modeling treatments and predicting outcomes.
    Journal of the National Cancer Institute, 1995, Dec-20, Volume: 87, Issue:24

    Topics: Adolescent; Adult; Aged; Brachytherapy; Brain Neoplasms; Carmustine; Child; Combined Modality Therap

1995
Accelerated hyperfractionated radiation therapy for malignant glioma. A phase II study.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Combined M

1995
Accelerated hyperfractionated radiation therapy for malignant glioma. A phase II study.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Combined M

1995
Accelerated hyperfractionated radiation therapy for malignant glioma. A phase II study.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Combined M

1995
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group.
    Lancet (London, England), 1995, Apr-22, Volume: 345, Issue:8956

    Topics: Biodegradation, Environmental; Brain Neoplasms; Carmustine; Drug Implants; Female; Glioma; Humans; M

1995
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group.
    Lancet (London, England), 1995, Apr-22, Volume: 345, Issue:8956

    Topics: Biodegradation, Environmental; Brain Neoplasms; Carmustine; Drug Implants; Female; Glioma; Humans; M

1995
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group.
    Lancet (London, England), 1995, Apr-22, Volume: 345, Issue:8956

    Topics: Biodegradation, Environmental; Brain Neoplasms; Carmustine; Drug Implants; Female; Glioma; Humans; M

1995
Quality-adjusted survival analysis of malignant glioma. Patients treated with twice-daily radiation (RT) and carmustine: a report of Radiation Therapy Oncology Group (RTOG) 83-02.
    International journal of radiation oncology, biology, physics, 1995, Feb-01, Volume: 31, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; M

1995
Quality-adjusted survival analysis of malignant glioma. Patients treated with twice-daily radiation (RT) and carmustine: a report of Radiation Therapy Oncology Group (RTOG) 83-02.
    International journal of radiation oncology, biology, physics, 1995, Feb-01, Volume: 31, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; M

1995
Quality-adjusted survival analysis of malignant glioma. Patients treated with twice-daily radiation (RT) and carmustine: a report of Radiation Therapy Oncology Group (RTOG) 83-02.
    International journal of radiation oncology, biology, physics, 1995, Feb-01, Volume: 31, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; M

1995
Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Interfe

1995
Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Interfe

1995
Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Interfe

1995
White matter changes are correlated significantly with radiation dose. Observations from a randomized dose-escalation trial for malignant glioma (Radiation Therapy Oncology Group 83-02).
    Cancer, 1994, Nov-15, Volume: 74, Issue:10

    Topics: Brain; Brain Neoplasms; Carmustine; Dose-Response Relationship, Radiation; Female; Glioma; Humans; M

1994
White matter changes are correlated significantly with radiation dose. Observations from a randomized dose-escalation trial for malignant glioma (Radiation Therapy Oncology Group 83-02).
    Cancer, 1994, Nov-15, Volume: 74, Issue:10

    Topics: Brain; Brain Neoplasms; Carmustine; Dose-Response Relationship, Radiation; Female; Glioma; Humans; M

1994
White matter changes are correlated significantly with radiation dose. Observations from a randomized dose-escalation trial for malignant glioma (Radiation Therapy Oncology Group 83-02).
    Cancer, 1994, Nov-15, Volume: 74, Issue:10

    Topics: Brain; Brain Neoplasms; Carmustine; Dose-Response Relationship, Radiation; Female; Glioma; Humans; M

1994
Hyperfractionated radiation therapy (HFX RT) followed by multiagent chemotherapy (CHT) in patients with malignant glioma: a phase II study.
    International journal of radiation oncology, biology, physics, 1994, Dec-01, Volume: 30, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combi

1994
Hyperfractionated radiation therapy (HFX RT) followed by multiagent chemotherapy (CHT) in patients with malignant glioma: a phase II study.
    International journal of radiation oncology, biology, physics, 1994, Dec-01, Volume: 30, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combi

1994
Hyperfractionated radiation therapy (HFX RT) followed by multiagent chemotherapy (CHT) in patients with malignant glioma: a phase II study.
    International journal of radiation oncology, biology, physics, 1994, Dec-01, Volume: 30, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combi

1994
Adjuvant therapy with dibromodulcitol and BCNU increases survival of adults with malignant gliomas. EORTC Brain Tumor Group.
    Neurology, 1994, Volume: 44, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemothera

1994
Adjuvant therapy with dibromodulcitol and BCNU increases survival of adults with malignant gliomas. EORTC Brain Tumor Group.
    Neurology, 1994, Volume: 44, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemothera

1994
Adjuvant therapy with dibromodulcitol and BCNU increases survival of adults with malignant gliomas. EORTC Brain Tumor Group.
    Neurology, 1994, Volume: 44, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemothera

1994
Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors.
    Journal of neuro-oncology, 1993, Volume: 17, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1993
Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors.
    Journal of neuro-oncology, 1993, Volume: 17, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1993
Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors.
    Journal of neuro-oncology, 1993, Volume: 17, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1993
rhGM-CSF ameliorates neutropenia in patients with malignant glioma treated with BCNU.
    British journal of cancer, 1994, Volume: 69, Issue:3

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioblastoma; Glioma; Granulocyte-Macrophage Colony-Stim

1994
rhGM-CSF ameliorates neutropenia in patients with malignant glioma treated with BCNU.
    British journal of cancer, 1994, Volume: 69, Issue:3

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioblastoma; Glioma; Granulocyte-Macrophage Colony-Stim

1994
rhGM-CSF ameliorates neutropenia in patients with malignant glioma treated with BCNU.
    British journal of cancer, 1994, Volume: 69, Issue:3

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioblastoma; Glioma; Granulocyte-Macrophage Colony-Stim

1994
Comparison of the Cox model and the regression tree procedure in analysing a randomized clinical trial.
    Statistics in medicine, 1993, Dec-30, Volume: 12, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bias; Brain Neoplasms; Carmustine; Clin

1993
Comparison of the Cox model and the regression tree procedure in analysing a randomized clinical trial.
    Statistics in medicine, 1993, Dec-30, Volume: 12, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bias; Brain Neoplasms; Carmustine; Clin

1993
Comparison of the Cox model and the regression tree procedure in analysing a randomized clinical trial.
    Statistics in medicine, 1993, Dec-30, Volume: 12, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bias; Brain Neoplasms; Carmustine; Clin

1993
Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

1993
Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

1993
Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

1993
An analysis of radiotherapy data from the CNS cancer consortium's randomized prospective trial comparing AZQ to BCNU in the treatment of patients with primary malignant brain tumors. The CNS cancer consortium.
    American journal of clinical oncology, 1993, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine;

1993
An analysis of radiotherapy data from the CNS cancer consortium's randomized prospective trial comparing AZQ to BCNU in the treatment of patients with primary malignant brain tumors. The CNS cancer consortium.
    American journal of clinical oncology, 1993, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine;

1993
An analysis of radiotherapy data from the CNS cancer consortium's randomized prospective trial comparing AZQ to BCNU in the treatment of patients with primary malignant brain tumors. The CNS cancer consortium.
    American journal of clinical oncology, 1993, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine;

1993
Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:1

    Topics: Adult; Analysis of Variance; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carm

1993
Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:1

    Topics: Adult; Analysis of Variance; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carm

1993
Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:1

    Topics: Adult; Analysis of Variance; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carm

1993
Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine: a report of Radiation Therapy Oncology Group 83-02.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Carmustine; Combined Modality Therapy; Contraindications; Female; Glioma; Humans; Male; Middle Aged;

1993
Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine: a report of Radiation Therapy Oncology Group 83-02.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Carmustine; Combined Modality Therapy; Contraindications; Female; Glioma; Humans; Male; Middle Aged;

1993
Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine: a report of Radiation Therapy Oncology Group 83-02.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Carmustine; Combined Modality Therapy; Contraindications; Female; Glioma; Humans; Male; Middle Aged;

1993
Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas.
    Journal of neuro-oncology, 1995, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1995
Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas.
    Journal of neuro-oncology, 1995, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1995
Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas.
    Journal of neuro-oncology, 1995, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1995
Final report of a phase I/II trial of hyperfractionated and accelerated hyperfractionated radiation therapy with carmustine for adults with supratentorial malignant gliomas. Radiation Therapy Oncology Group Study 83-02.
    Cancer, 1996, Apr-15, Volume: 77, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; F

1996
Final report of a phase I/II trial of hyperfractionated and accelerated hyperfractionated radiation therapy with carmustine for adults with supratentorial malignant gliomas. Radiation Therapy Oncology Group Study 83-02.
    Cancer, 1996, Apr-15, Volume: 77, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; F

1996
Final report of a phase I/II trial of hyperfractionated and accelerated hyperfractionated radiation therapy with carmustine for adults with supratentorial malignant gliomas. Radiation Therapy Oncology Group Study 83-02.
    Cancer, 1996, Apr-15, Volume: 77, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; F

1996
The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial.
    Journal of neuro-oncology, 1995, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain N

1995
The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial.
    Journal of neuro-oncology, 1995, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain N

1995
The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial.
    Journal of neuro-oncology, 1995, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain N

1995
Contemporary chemotherapy issues for children with brainstem gliomas.
    Pediatric neurosurgery, 1996, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carboplatin; Carmustine; Dose-Response Relations

1996
Contemporary chemotherapy issues for children with brainstem gliomas.
    Pediatric neurosurgery, 1996, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carboplatin; Carmustine; Dose-Response Relations

1996
Contemporary chemotherapy issues for children with brainstem gliomas.
    Pediatric neurosurgery, 1996, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carboplatin; Carmustine; Dose-Response Relations

1996
High-dose carmustine for high-grade gliomas in childhood.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Brain Neoplasms; Carmust

1997
High-dose carmustine for high-grade gliomas in childhood.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Brain Neoplasms; Carmust

1997
High-dose carmustine for high-grade gliomas in childhood.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Brain Neoplasms; Carmust

1997
Treatment of recurrent malignant glioma with BCNU-fluosol and oxygen inhalation. A phase I-II study.
    Journal of neuro-oncology, 1997, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine

1997
Treatment of recurrent malignant glioma with BCNU-fluosol and oxygen inhalation. A phase I-II study.
    Journal of neuro-oncology, 1997, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine

1997
Treatment of recurrent malignant glioma with BCNU-fluosol and oxygen inhalation. A phase I-II study.
    Journal of neuro-oncology, 1997, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine

1997
Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study.
    Neurosurgery, 1997, Volume: 41, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

1997
Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study.
    Neurosurgery, 1997, Volume: 41, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

1997
Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study.
    Neurosurgery, 1997, Volume: 41, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

1997
Phase II trial with BCNU plus alpha-interferon in patients with recurrent high-grade gliomas.
    American journal of clinical oncology, 1997, Volume: 20, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

1997
Phase II trial with BCNU plus alpha-interferon in patients with recurrent high-grade gliomas.
    American journal of clinical oncology, 1997, Volume: 20, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

1997
Phase II trial with BCNU plus alpha-interferon in patients with recurrent high-grade gliomas.
    American journal of clinical oncology, 1997, Volume: 20, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

1997
Phase I evaluation of radiation combined with recombinant interferon alpha-2a and BCNU for patients with high-grade glioma.
    International journal of radiation oncology, biology, physics, 1998, Jan-15, Volume: 40, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

1998
Phase I evaluation of radiation combined with recombinant interferon alpha-2a and BCNU for patients with high-grade glioma.
    International journal of radiation oncology, biology, physics, 1998, Jan-15, Volume: 40, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

1998
Phase I evaluation of radiation combined with recombinant interferon alpha-2a and BCNU for patients with high-grade glioma.
    International journal of radiation oncology, biology, physics, 1998, Jan-15, Volume: 40, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

1998
Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

1998
Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

1998
Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

1998
Phase I and pharmacokinetic study of preirradiation chemotherapy with BCNU, cisplatin, etoposide, and accelerated radiation therapy in patients with high-grade glioma.
    International journal of radiation oncology, biology, physics, 1998, Dec-01, Volume: 42, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carmustin

1998
Phase I and pharmacokinetic study of preirradiation chemotherapy with BCNU, cisplatin, etoposide, and accelerated radiation therapy in patients with high-grade glioma.
    International journal of radiation oncology, biology, physics, 1998, Dec-01, Volume: 42, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carmustin

1998
Phase I and pharmacokinetic study of preirradiation chemotherapy with BCNU, cisplatin, etoposide, and accelerated radiation therapy in patients with high-grade glioma.
    International journal of radiation oncology, biology, physics, 1998, Dec-01, Volume: 42, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carmustin

1998
Phase I evaluation of preirradiation chemotherapy with carmustine and cisplatin and accelerated radiation therapy in patients with high-grade gliomas.
    Neurosurgery, 1999, Volume: 44, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1999
Phase I evaluation of preirradiation chemotherapy with carmustine and cisplatin and accelerated radiation therapy in patients with high-grade gliomas.
    Neurosurgery, 1999, Volume: 44, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1999
Phase I evaluation of preirradiation chemotherapy with carmustine and cisplatin and accelerated radiation therapy in patients with high-grade gliomas.
    Neurosurgery, 1999, Volume: 44, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1999
A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.
    Cancer, 2001, Jul-15, Volume: 92, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

2001
A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.
    Cancer, 2001, Jul-15, Volume: 92, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

2001
A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.
    Cancer, 2001, Jul-15, Volume: 92, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

2001
Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, May-01, Volume: 20, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Carm

2002
Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, May-01, Volume: 20, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Carm

2002
Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, May-01, Volume: 20, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Carm

2002
Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2002, Jun-01, Volume: 53, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Diseases; Carm

2002
Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2002, Jun-01, Volume: 53, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Diseases; Carm

2002
Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2002, Jun-01, Volume: 53, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Diseases; Carm

2002
Chemotherapy: adjuvant to surgery and radiation therapy.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma;

1975
Chemotherapy: adjuvant to surgery and radiation therapy.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma;

1975
Chemotherapy: adjuvant to surgery and radiation therapy.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma;

1975
Brain Tumor Study Group: a survey of current activities.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Glioma; Humans; National Ins

1977
Brain Tumor Study Group: a survey of current activities.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Glioma; Humans; National Ins

1977
Brain Tumor Study Group: a survey of current activities.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Glioma; Humans; National Ins

1977
BCNU (NSC-409962) and procarbazine (NSC-77213) treatment for malignant brain tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, C

1976
BCNU (NSC-409962) and procarbazine (NSC-77213) treatment for malignant brain tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, C

1976
BCNU (NSC-409962) and procarbazine (NSC-77213) treatment for malignant brain tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, C

1976
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis

1977
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis

1977
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Divis

1977
A phase III comparison of BCNU, hydroxyurea, and radiation therapy to BCNU and radiation therapy for treatment of primary malignant gliomas.
    Journal of neurosurgery, 1979, Volume: 51, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cobalt Radioisotope

1979
A phase III comparison of BCNU, hydroxyurea, and radiation therapy to BCNU and radiation therapy for treatment of primary malignant gliomas.
    Journal of neurosurgery, 1979, Volume: 51, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cobalt Radioisotope

1979
A phase III comparison of BCNU, hydroxyurea, and radiation therapy to BCNU and radiation therapy for treatment of primary malignant gliomas.
    Journal of neurosurgery, 1979, Volume: 51, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cobalt Radioisotope

1979
Preliminary results of a phase III comparison study of BCNU, hydroxyurea and radiation to BCNU and radiation.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioblastoma; Glio

1979
Preliminary results of a phase III comparison study of BCNU, hydroxyurea and radiation to BCNU and radiation.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioblastoma; Glio

1979
Preliminary results of a phase III comparison study of BCNU, hydroxyurea and radiation to BCNU and radiation.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioblastoma; Glio

1979
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial.
    Journal of neurosurgery, 1978, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Clinical Trials as Topic; Evaluation St

1978
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial.
    Journal of neurosurgery, 1978, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Clinical Trials as Topic; Evaluation St

1978
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial.
    Journal of neurosurgery, 1978, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Clinical Trials as Topic; Evaluation St

1978
Adjuvant nitrosourea therapy for glioblastoma.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Fema

1976
Adjuvant nitrosourea therapy for glioblastoma.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Fema

1976
Adjuvant nitrosourea therapy for glioblastoma.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Fema

1976
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Mod

1992
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Mod

1992
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Mod

1992
A randomized trial of accelerated hyperfractionated radiation therapy and bis-chloroethyl nitrosourea for malignant glioma. A preliminary report of Radiation Therapy Oncology Group 83-02.
    Cancer, 1992, Dec-15, Volume: 70, Issue:12

    Topics: Carmustine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Glioma; Humans

1992
A randomized trial of accelerated hyperfractionated radiation therapy and bis-chloroethyl nitrosourea for malignant glioma. A preliminary report of Radiation Therapy Oncology Group 83-02.
    Cancer, 1992, Dec-15, Volume: 70, Issue:12

    Topics: Carmustine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Glioma; Humans

1992
A randomized trial of accelerated hyperfractionated radiation therapy and bis-chloroethyl nitrosourea for malignant glioma. A preliminary report of Radiation Therapy Oncology Group 83-02.
    Cancer, 1992, Dec-15, Volume: 70, Issue:12

    Topics: Carmustine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Glioma; Humans

1992
Carboplatin combined with carmustine and etoposide in the treatment of glioblastoma.
    Italian journal of neurological sciences, 1992, Volume: 13, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carmustine; Eto

1992
Carboplatin combined with carmustine and etoposide in the treatment of glioblastoma.
    Italian journal of neurological sciences, 1992, Volume: 13, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carmustine; Eto

1992
Carboplatin combined with carmustine and etoposide in the treatment of glioblastoma.
    Italian journal of neurological sciences, 1992, Volume: 13, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carmustine; Eto

1992
A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma.
    Journal of neurosurgery, 1992, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modali

1992
A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma.
    Journal of neurosurgery, 1992, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modali

1992
A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma.
    Journal of neurosurgery, 1992, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modali

1992
Phase I study of BCNU and intravenous 6-mercaptopurine in patients with anaplastic gliomas.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem

1992
Phase I study of BCNU and intravenous 6-mercaptopurine in patients with anaplastic gliomas.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem

1992
Phase I study of BCNU and intravenous 6-mercaptopurine in patients with anaplastic gliomas.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem

1992
Combined intra-arterial chemotherapy and irradiation of malignant gliomas.
    Acta oncologica (Stockholm, Sweden), 1991, Volume: 30, Issue:7

    Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Carmustine; Combined Modality Therapy; Eye Diseases

1991
Combined intra-arterial chemotherapy and irradiation of malignant gliomas.
    Acta oncologica (Stockholm, Sweden), 1991, Volume: 30, Issue:7

    Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Carmustine; Combined Modality Therapy; Eye Diseases

1991
Combined intra-arterial chemotherapy and irradiation of malignant gliomas.
    Acta oncologica (Stockholm, Sweden), 1991, Volume: 30, Issue:7

    Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Carmustine; Combined Modality Therapy; Eye Diseases

1991
Cisplatin and etoposide combination therapy for primary glial tumors: preliminary results.
    Italian journal of neurological sciences, 1991, Volume: 12, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cis

1991
Cisplatin and etoposide combination therapy for primary glial tumors: preliminary results.
    Italian journal of neurological sciences, 1991, Volume: 12, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cis

1991
Cisplatin and etoposide combination therapy for primary glial tumors: preliminary results.
    Italian journal of neurological sciences, 1991, Volume: 12, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cis

1991
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas.
    Journal of neurosurgery, 1991, Volume: 74, Issue:3

    Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinations; Drug Implants; F

1991
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas.
    Journal of neurosurgery, 1991, Volume: 74, Issue:3

    Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinations; Drug Implants; F

1991
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas.
    Journal of neurosurgery, 1991, Volume: 74, Issue:3

    Topics: Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinations; Drug Implants; F

1991
Alternating sequential intracarotid BCNU and cisplatin in recurrent malignant glioma.
    Cancer, 1991, Jul-01, Volume: 68, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modalit

1991
Alternating sequential intracarotid BCNU and cisplatin in recurrent malignant glioma.
    Cancer, 1991, Jul-01, Volume: 68, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modalit

1991
Alternating sequential intracarotid BCNU and cisplatin in recurrent malignant glioma.
    Cancer, 1991, Jul-01, Volume: 68, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modalit

1991
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

1990
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

1990
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

1990
Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Astrocytoma; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; H

1989
Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Astrocytoma; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; H

1989
Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Astrocytoma; Carmustine; Combined Modality Therapy; Glioblastoma; Glioma; H

1989
Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001.
    Journal of neurosurgery, 1989, Volume: 71, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cerebellar Neoplasms; Clinical Trials as

1989
Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001.
    Journal of neurosurgery, 1989, Volume: 71, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cerebellar Neoplasms; Clinical Trials as

1989
Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001.
    Journal of neurosurgery, 1989, Volume: 71, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cerebellar Neoplasms; Clinical Trials as

1989
Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; C

1985
Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; C

1985
Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; C

1985
Combined modality approach to treatment of malignant gliomas--re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: a joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology Group.
    NCI monographs : a publication of the National Cancer Institute, 1988, Issue:6

    Topics: Adult; Age Factors; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy

1988
Combined modality approach to treatment of malignant gliomas--re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: a joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology Group.
    NCI monographs : a publication of the National Cancer Institute, 1988, Issue:6

    Topics: Adult; Age Factors; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy

1988
Combined modality approach to treatment of malignant gliomas--re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: a joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology Group.
    NCI monographs : a publication of the National Cancer Institute, 1988, Issue:6

    Topics: Adult; Age Factors; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy

1988
Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:3

    Topics: Adult; Aged; Ambroxol; Brain Neoplasms; Bromhexine; Carmustine; Clinical Trials as Topic; Double-Bli

1987
Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:3

    Topics: Adult; Aged; Ambroxol; Brain Neoplasms; Bromhexine; Carmustine; Clinical Trials as Topic; Double-Bli

1987
Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:3

    Topics: Adult; Aged; Ambroxol; Brain Neoplasms; Bromhexine; Carmustine; Clinical Trials as Topic; Double-Bli

1987
Pulmonary toxicity of carmustine in patients treated for malignant glioma.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relation

1986
Pulmonary toxicity of carmustine in patients treated for malignant glioma.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relation

1986
Pulmonary toxicity of carmustine in patients treated for malignant glioma.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relation

1986
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:10

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Gliom

1986
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:10

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Gliom

1986
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:10

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Gliom

1986
Reevaluating the efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Humans; Infusions, In

1987
Reevaluating the efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Humans; Infusions, In

1987
Reevaluating the efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Humans; Infusions, In

1987
Randomized phase III trial of single versus multiple chemotherapeutic treatment following surgery and during radiotherapy for patients with anaplastic gliomas.
    Surgical neurology, 1987, Volume: 27, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

1987
Randomized phase III trial of single versus multiple chemotherapeutic treatment following surgery and during radiotherapy for patients with anaplastic gliomas.
    Surgical neurology, 1987, Volume: 27, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

1987
Randomized phase III trial of single versus multiple chemotherapeutic treatment following surgery and during radiotherapy for patients with anaplastic gliomas.
    Surgical neurology, 1987, Volume: 27, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

1987
Sister chromatid exchange induction in patients with anaplastic gliomas undergoing treatment with radiation plus diaziquone or 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1987, Jan-15, Volume: 47, Issue:2

    Topics: Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1987
Sister chromatid exchange induction in patients with anaplastic gliomas undergoing treatment with radiation plus diaziquone or 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1987, Jan-15, Volume: 47, Issue:2

    Topics: Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1987
Sister chromatid exchange induction in patients with anaplastic gliomas undergoing treatment with radiation plus diaziquone or 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1987, Jan-15, Volume: 47, Issue:2

    Topics: Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1987
The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine.
    JAMA, 1972, Oct-30, Volume: 222, Issue:5

    Topics: Astrocytoma; Brain Neoplasms; Carcinosarcoma; Carmustine; Cerebral Angiography; Ependymoma; Evaluati

1972
The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine.
    JAMA, 1972, Oct-30, Volume: 222, Issue:5

    Topics: Astrocytoma; Brain Neoplasms; Carcinosarcoma; Carmustine; Cerebral Angiography; Ependymoma; Evaluati

1972
The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine.
    JAMA, 1972, Oct-30, Volume: 222, Issue:5

    Topics: Astrocytoma; Brain Neoplasms; Carcinosarcoma; Carmustine; Cerebral Angiography; Ependymoma; Evaluati

1972

Other Studies

387 other studies available for carmustine and Glioma

ArticleYear
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Forma

1996
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Forma

1996
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Forma

1996
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
    Journal of medicinal chemistry, 2006, Sep-21, Volume: 49, Issue:19

    Topics: Animals; Antineoplastic Agents; Astrocytes; Biphenyl Compounds; Cell Line, Tumor; Cells, Cultured; D

2006
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
    Journal of medicinal chemistry, 2006, Sep-21, Volume: 49, Issue:19

    Topics: Animals; Antineoplastic Agents; Astrocytes; Biphenyl Compounds; Cell Line, Tumor; Cells, Cultured; D

2006
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
    Journal of medicinal chemistry, 2006, Sep-21, Volume: 49, Issue:19

    Topics: Animals; Antineoplastic Agents; Astrocytes; Biphenyl Compounds; Cell Line, Tumor; Cells, Cultured; D

2006
Supramolecular Hydrogel Based Post-Surgical Implant System for Hydrophobic Drug Delivery Against Glioma Recurrence.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Animals; Biocompatible Materials; Carmustine; Curcumin; Drug Delivery Systems; Glioma; Humans; Hydro

2022
Supramolecular Hydrogel Based Post-Surgical Implant System for Hydrophobic Drug Delivery Against Glioma Recurrence.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Animals; Biocompatible Materials; Carmustine; Curcumin; Drug Delivery Systems; Glioma; Humans; Hydro

2022
Supramolecular Hydrogel Based Post-Surgical Implant System for Hydrophobic Drug Delivery Against Glioma Recurrence.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Animals; Biocompatible Materials; Carmustine; Curcumin; Drug Delivery Systems; Glioma; Humans; Hydro

2022
Cerebral Edema Due to Chemotherapeutic Wafer Implantation for Malignant Glioma: Registry Study of Correlation with Perioperative Epileptic Seizures.
    Neurologia medico-chirurgica, 2022, Jul-15, Volume: 62, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Combined Modalit

2022
Cerebral Edema Due to Chemotherapeutic Wafer Implantation for Malignant Glioma: Registry Study of Correlation with Perioperative Epileptic Seizures.
    Neurologia medico-chirurgica, 2022, Jul-15, Volume: 62, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Combined Modalit

2022
Cerebral Edema Due to Chemotherapeutic Wafer Implantation for Malignant Glioma: Registry Study of Correlation with Perioperative Epileptic Seizures.
    Neurologia medico-chirurgica, 2022, Jul-15, Volume: 62, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Combined Modalit

2022
Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Humans; Hydrogels; Neoplasm Recurrence, Local

2022
Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Humans; Hydrogels; Neoplasm Recurrence, Local

2022
Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Humans; Hydrogels; Neoplasm Recurrence, Local

2022
Molecular characteristics of incidental lower-grade glioma for treatment decision-making.
    Journal of neurosurgery, 2023, 03-01, Volume: 138, Issue:3

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Prognosis; Retrospe

2023
Molecular characteristics of incidental lower-grade glioma for treatment decision-making.
    Journal of neurosurgery, 2023, 03-01, Volume: 138, Issue:3

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Prognosis; Retrospe

2023
Molecular characteristics of incidental lower-grade glioma for treatment decision-making.
    Journal of neurosurgery, 2023, 03-01, Volume: 138, Issue:3

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Prognosis; Retrospe

2023
Intraoperative Ventricular Opening has No Effect on Complication Development Following BCNU Wafer Implantation for Malignant Glioma.
    World neurosurgery, 2023, Volume: 171

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; H

2023
Intraoperative Ventricular Opening has No Effect on Complication Development Following BCNU Wafer Implantation for Malignant Glioma.
    World neurosurgery, 2023, Volume: 171

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; H

2023
Intraoperative Ventricular Opening has No Effect on Complication Development Following BCNU Wafer Implantation for Malignant Glioma.
    World neurosurgery, 2023, Volume: 171

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; H

2023
Intracranial nanomedicine-gel with deep brain-penetration for glioblastoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Animals; Brain; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Glioblastoma; Glioma; Nano

2023
Intracranial nanomedicine-gel with deep brain-penetration for glioblastoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Animals; Brain; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Glioblastoma; Glioma; Nano

2023
Intracranial nanomedicine-gel with deep brain-penetration for glioblastoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Animals; Brain; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Glioblastoma; Glioma; Nano

2023
Newly Diagnosed High-Grade Glioma Surgery with Carmustine Wafers Implantation. A Long-Term Nationwide Retrospective Study.
    World neurosurgery, 2023, Volume: 173

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male;

2023
Newly Diagnosed High-Grade Glioma Surgery with Carmustine Wafers Implantation. A Long-Term Nationwide Retrospective Study.
    World neurosurgery, 2023, Volume: 173

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male;

2023
Newly Diagnosed High-Grade Glioma Surgery with Carmustine Wafers Implantation. A Long-Term Nationwide Retrospective Study.
    World neurosurgery, 2023, Volume: 173

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male;

2023
Recurrent high grade glioma surgery with carmustine wafers implantation: a long-term nationwide retrospective study.
    Journal of neuro-oncology, 2023, Volume: 162, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male;

2023
Recurrent high grade glioma surgery with carmustine wafers implantation: a long-term nationwide retrospective study.
    Journal of neuro-oncology, 2023, Volume: 162, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male;

2023
Recurrent high grade glioma surgery with carmustine wafers implantation: a long-term nationwide retrospective study.
    Journal of neuro-oncology, 2023, Volume: 162, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male;

2023
MRT-boost as the last fraction may be the most efficient irradiation schedule for increased survival times in a rat glioma model.
    Journal of synchrotron radiation, 2023, May-01, Volume: 30, Issue:Pt 3

    Topics: Animals; Brain Neoplasms; Carmustine; Dose Fractionation, Radiation; Glioma; Radiotherapy; Rats; Syn

2023
MRT-boost as the last fraction may be the most efficient irradiation schedule for increased survival times in a rat glioma model.
    Journal of synchrotron radiation, 2023, May-01, Volume: 30, Issue:Pt 3

    Topics: Animals; Brain Neoplasms; Carmustine; Dose Fractionation, Radiation; Glioma; Radiotherapy; Rats; Syn

2023
MRT-boost as the last fraction may be the most efficient irradiation schedule for increased survival times in a rat glioma model.
    Journal of synchrotron radiation, 2023, May-01, Volume: 30, Issue:Pt 3

    Topics: Animals; Brain Neoplasms; Carmustine; Dose Fractionation, Radiation; Glioma; Radiotherapy; Rats; Syn

2023
Arsenite-induced Radiosensitization of Glioma Cells Is Dependent on p53 Deficiency.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Arsenites; Carbon; Carmustine; Cell Line, Tumor; Cell Survival; Glioma; Humans; Tumor Suppressor Pro

2023
Arsenite-induced Radiosensitization of Glioma Cells Is Dependent on p53 Deficiency.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Arsenites; Carbon; Carmustine; Cell Line, Tumor; Cell Survival; Glioma; Humans; Tumor Suppressor Pro

2023
Arsenite-induced Radiosensitization of Glioma Cells Is Dependent on p53 Deficiency.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Arsenites; Carbon; Carmustine; Cell Line, Tumor; Cell Survival; Glioma; Humans; Tumor Suppressor Pro

2023
A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Compounding; Gliom

2019
A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Compounding; Gliom

2019
A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Compounding; Gliom

2019
Implantation of carmustine wafers (Gliadel
    Journal of neuro-oncology, 2020, Volume: 147, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Infusi

2020
Implantation of carmustine wafers (Gliadel
    Journal of neuro-oncology, 2020, Volume: 147, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Infusi

2020
Implantation of carmustine wafers (Gliadel
    Journal of neuro-oncology, 2020, Volume: 147, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Infusi

2020
Glycolytic inhibition by 3-bromopyruvate increases the cytotoxic effects of chloroethylnitrosoureas to human glioma cells and the DNA interstrand cross-links formation.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot

2020
Glycolytic inhibition by 3-bromopyruvate increases the cytotoxic effects of chloroethylnitrosoureas to human glioma cells and the DNA interstrand cross-links formation.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot

2020
Glycolytic inhibition by 3-bromopyruvate increases the cytotoxic effects of chloroethylnitrosoureas to human glioma cells and the DNA interstrand cross-links formation.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot

2020
FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:17

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Carmustine; Cell Movement; Cell Proliferation;

2020
FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:17

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Carmustine; Cell Movement; Cell Proliferation;

2020
FKBP51 acts as a biomarker of early metastasis and is related to carmustine sensitivity in human glioma cells.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:17

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Carmustine; Cell Movement; Cell Proliferation;

2020
Safety of Gliadel Implant for Malignant Glioma: Report of Postmarketing Surveillance in Japan.
    Neurologia medico-chirurgica, 2021, Sep-15, Volume: 61, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Glioma; Humans; Japa

2021
Safety of Gliadel Implant for Malignant Glioma: Report of Postmarketing Surveillance in Japan.
    Neurologia medico-chirurgica, 2021, Sep-15, Volume: 61, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Glioma; Humans; Japa

2021
Safety of Gliadel Implant for Malignant Glioma: Report of Postmarketing Surveillance in Japan.
    Neurologia medico-chirurgica, 2021, Sep-15, Volume: 61, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Decanoic Acids; Glioma; Humans; Japa

2021
Implantation of Carmustine wafers after resection of malignant glioma with and without opening of the ventricular system.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans; Neopl

2021
Implantation of Carmustine wafers after resection of malignant glioma with and without opening of the ventricular system.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans; Neopl

2021
Implantation of Carmustine wafers after resection of malignant glioma with and without opening of the ventricular system.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans; Neopl

2021
Inhibitors of GLUT/SLC2A Enhance the Action of BCNU and Temozolomide against High-Grade Gliomas.
    Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Carmustine; Cell Line, Tumor; Cell

2017
Inhibitors of GLUT/SLC2A Enhance the Action of BCNU and Temozolomide against High-Grade Gliomas.
    Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Carmustine; Cell Line, Tumor; Cell

2017
Inhibitors of GLUT/SLC2A Enhance the Action of BCNU and Temozolomide against High-Grade Gliomas.
    Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Carmustine; Cell Line, Tumor; Cell

2017
Verapamil augments carmustine- and irradiation-induced senescence in glioma cells by reducing intracellular reactive oxygen species and calcium ion levels.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium; Calcium Channels, L-Type; Carmustine; Cell

2017
Verapamil augments carmustine- and irradiation-induced senescence in glioma cells by reducing intracellular reactive oxygen species and calcium ion levels.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium; Calcium Channels, L-Type; Carmustine; Cell

2017
Verapamil augments carmustine- and irradiation-induced senescence in glioma cells by reducing intracellular reactive oxygen species and calcium ion levels.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium; Calcium Channels, L-Type; Carmustine; Cell

2017
Space-Occupying Tumor Bed Cysts as a Complication of Modern Treatment for High-Grade Glioma.
    World neurosurgery, 2017, Volume: 104

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Edema; Carmustine; Central Nervous System Cysts; C

2017
Space-Occupying Tumor Bed Cysts as a Complication of Modern Treatment for High-Grade Glioma.
    World neurosurgery, 2017, Volume: 104

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Edema; Carmustine; Central Nervous System Cysts; C

2017
Space-Occupying Tumor Bed Cysts as a Complication of Modern Treatment for High-Grade Glioma.
    World neurosurgery, 2017, Volume: 104

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Edema; Carmustine; Central Nervous System Cysts; C

2017
Novel Application of Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging for Diagnosis of External Hydrocephalus.
    World neurosurgery, 2018, Volume: 109

    Topics: Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carmustine; Decanoic Acids; Glioma; Human

2018
Novel Application of Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging for Diagnosis of External Hydrocephalus.
    World neurosurgery, 2018, Volume: 109

    Topics: Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carmustine; Decanoic Acids; Glioma; Human

2018
Novel Application of Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging for Diagnosis of External Hydrocephalus.
    World neurosurgery, 2018, Volume: 109

    Topics: Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carmustine; Decanoic Acids; Glioma; Human

2018
MiR-21 enhanced glioma cells resistance to carmustine via decreasing Spry2 expression.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:22

    Topics: Antagomirs; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member

2017
MiR-21 enhanced glioma cells resistance to carmustine via decreasing Spry2 expression.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:22

    Topics: Antagomirs; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member

2017
MiR-21 enhanced glioma cells resistance to carmustine via decreasing Spry2 expression.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:22

    Topics: Antagomirs; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member

2017
Symptomatic Remote Cyst after BCNU Wafer Implantation for Malignant Glioma.
    Neurologia medico-chirurgica, 2018, Jun-15, Volume: 58, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Central Nervous System Cysts;

2018
Symptomatic Remote Cyst after BCNU Wafer Implantation for Malignant Glioma.
    Neurologia medico-chirurgica, 2018, Jun-15, Volume: 58, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Central Nervous System Cysts;

2018
Symptomatic Remote Cyst after BCNU Wafer Implantation for Malignant Glioma.
    Neurologia medico-chirurgica, 2018, Jun-15, Volume: 58, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Central Nervous System Cysts;

2018
Importance and accuracy of intraoperative frozen section diagnosis of the resection margin for effective carmustine wafer implantation.
    Brain tumor pathology, 2018, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2018
Importance and accuracy of intraoperative frozen section diagnosis of the resection margin for effective carmustine wafer implantation.
    Brain tumor pathology, 2018, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2018
Importance and accuracy of intraoperative frozen section diagnosis of the resection margin for effective carmustine wafer implantation.
    Brain tumor pathology, 2018, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2018
Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cann

2018
Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cann

2018
Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cann

2018
Pep-1&borneol-Bifunctionalized Carmustine-Loaded Micelles Enhance Anti-Glioma Efficacy Through Tumor-Targeting and BBB-Penetrating.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:5

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Brain Neoplasms; Camphanes; Carmustine; Cell Line, T

2019
Pep-1&borneol-Bifunctionalized Carmustine-Loaded Micelles Enhance Anti-Glioma Efficacy Through Tumor-Targeting and BBB-Penetrating.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:5

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Brain Neoplasms; Camphanes; Carmustine; Cell Line, T

2019
Pep-1&borneol-Bifunctionalized Carmustine-Loaded Micelles Enhance Anti-Glioma Efficacy Through Tumor-Targeting and BBB-Penetrating.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:5

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Brain Neoplasms; Camphanes; Carmustine; Cell Line, T

2019
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cadherins; Carmustine; Cell Line, Tumor; Drug Re

2014
Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cadherins; Carmustine; Cell Line, Tumor; Drug Re

2014
Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cadherins; Carmustine; Cell Line, Tumor; Drug Re

2014
Accelerated hazards model based on parametric families generalized with Bernstein polynomials.
    Biometrics, 2014, Volume: 70, Issue:1

    Topics: Bayes Theorem; Brain Neoplasms; Carmustine; Computer Simulation; Data Interpretation, Statistical; G

2014
Accelerated hazards model based on parametric families generalized with Bernstein polynomials.
    Biometrics, 2014, Volume: 70, Issue:1

    Topics: Bayes Theorem; Brain Neoplasms; Carmustine; Computer Simulation; Data Interpretation, Statistical; G

2014
Accelerated hazards model based on parametric families generalized with Bernstein polynomials.
    Biometrics, 2014, Volume: 70, Issue:1

    Topics: Bayes Theorem; Brain Neoplasms; Carmustine; Computer Simulation; Data Interpretation, Statistical; G

2014
4E-BP1 regulates the sensitivity of human glioma cells to chemotherapy through PI3K/Akt/mTOR-independent pathway.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Prot

2014
4E-BP1 regulates the sensitivity of human glioma cells to chemotherapy through PI3K/Akt/mTOR-independent pathway.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Prot

2014
4E-BP1 regulates the sensitivity of human glioma cells to chemotherapy through PI3K/Akt/mTOR-independent pathway.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Prot

2014
Intraoperative pathological diagnosis in 205 glioma patients in the pre-BCNU wafer era: retrospective analysis with intraoperative implantation of BCNU wafers in mind.
    Brain tumor pathology, 2014, Volume: 31, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Frozen Sections

2014
Intraoperative pathological diagnosis in 205 glioma patients in the pre-BCNU wafer era: retrospective analysis with intraoperative implantation of BCNU wafers in mind.
    Brain tumor pathology, 2014, Volume: 31, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Frozen Sections

2014
Intraoperative pathological diagnosis in 205 glioma patients in the pre-BCNU wafer era: retrospective analysis with intraoperative implantation of BCNU wafers in mind.
    Brain tumor pathology, 2014, Volume: 31, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Frozen Sections

2014
Carmustine (BCNU) plus Teniposide (VM26) in recurrent malignant glioma.
    Oncology, 2014, Volume: 86, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Disease-Fr

2014
Carmustine (BCNU) plus Teniposide (VM26) in recurrent malignant glioma.
    Oncology, 2014, Volume: 86, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Disease-Fr

2014
Carmustine (BCNU) plus Teniposide (VM26) in recurrent malignant glioma.
    Oncology, 2014, Volume: 86, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Disease-Fr

2014
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2014
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2014
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2014
Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.
    Journal of neuroscience methods, 2014, Dec-30, Volume: 238

    Topics: Animals; Antineoplastic Agents; Brain Stem; Brain Stem Neoplasms; Carmustine; Catheters; Convection;

2014
Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.
    Journal of neuroscience methods, 2014, Dec-30, Volume: 238

    Topics: Animals; Antineoplastic Agents; Brain Stem; Brain Stem Neoplasms; Carmustine; Catheters; Convection;

2014
Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.
    Journal of neuroscience methods, 2014, Dec-30, Volume: 238

    Topics: Animals; Antineoplastic Agents; Brain Stem; Brain Stem Neoplasms; Carmustine; Catheters; Convection;

2014
Redox proteomics reveal stress responsive proteins linking peroxiredoxin-1 status in glioma to chemosensitivity and oxidative stress.
    Biochimica et biophysica acta, 2015, Volume: 1854, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; DNA Damage; Drug Resistance, Neopla

2015
Redox proteomics reveal stress responsive proteins linking peroxiredoxin-1 status in glioma to chemosensitivity and oxidative stress.
    Biochimica et biophysica acta, 2015, Volume: 1854, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; DNA Damage; Drug Resistance, Neopla

2015
Redox proteomics reveal stress responsive proteins linking peroxiredoxin-1 status in glioma to chemosensitivity and oxidative stress.
    Biochimica et biophysica acta, 2015, Volume: 1854, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; DNA Damage; Drug Resistance, Neopla

2015
Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells.
    BMC cancer, 2015, Mar-13, Volume: 15

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Carmustine; Cell Line, Tumor; Cell Proliferation; D

2015
Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells.
    BMC cancer, 2015, Mar-13, Volume: 15

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Carmustine; Cell Line, Tumor; Cell Proliferation; D

2015
Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells.
    BMC cancer, 2015, Mar-13, Volume: 15

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Carmustine; Cell Line, Tumor; Cell Proliferation; D

2015
Development of resistance to antiglioma agents in rat C6 cells caused collateral sensitivity to doxorubicin.
    Experimental cell research, 2015, Jul-15, Volume: 335, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regula

2015
Development of resistance to antiglioma agents in rat C6 cells caused collateral sensitivity to doxorubicin.
    Experimental cell research, 2015, Jul-15, Volume: 335, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regula

2015
Development of resistance to antiglioma agents in rat C6 cells caused collateral sensitivity to doxorubicin.
    Experimental cell research, 2015, Jul-15, Volume: 335, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regula

2015
[Risk Factors for Adverse Events after Implantation of BCNU Wafers in High-grade Gliomas].
    No shinkei geka. Neurological surgery, 2015, Volume: 43, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb

2015
[Risk Factors for Adverse Events after Implantation of BCNU Wafers in High-grade Gliomas].
    No shinkei geka. Neurological surgery, 2015, Volume: 43, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb

2015
[Risk Factors for Adverse Events after Implantation of BCNU Wafers in High-grade Gliomas].
    No shinkei geka. Neurological surgery, 2015, Volume: 43, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb

2015
Knockdown of Gli1 by small-interfering RNA enhances the effects of BCNU on the proliferation and apoptosis of glioma U251 cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Cycle; Cell Division; Cell Line, Tumo

2015
Knockdown of Gli1 by small-interfering RNA enhances the effects of BCNU on the proliferation and apoptosis of glioma U251 cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Cycle; Cell Division; Cell Line, Tumo

2015
Knockdown of Gli1 by small-interfering RNA enhances the effects of BCNU on the proliferation and apoptosis of glioma U251 cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Cycle; Cell Division; Cell Line, Tumo

2015
Evaluation of serial changes on computed tomography and magnetic resonance imaging after implantation of carmustine wafers in patients with malignant gliomas for differential diagnosis of tumor recurrence.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2016
Evaluation of serial changes on computed tomography and magnetic resonance imaging after implantation of carmustine wafers in patients with malignant gliomas for differential diagnosis of tumor recurrence.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2016
Evaluation of serial changes on computed tomography and magnetic resonance imaging after implantation of carmustine wafers in patients with malignant gliomas for differential diagnosis of tumor recurrence.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carm

2016
Early Postoperative Expansion of Parenchymal High-intensity Areas on T2-weighted Imaging Predicts Delayed Cerebral Edema Caused by Carmustine Wafer Implantation in Patients with High-grade Glioma.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2016, Jul-11, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Female; Gl

2016
Early Postoperative Expansion of Parenchymal High-intensity Areas on T2-weighted Imaging Predicts Delayed Cerebral Edema Caused by Carmustine Wafer Implantation in Patients with High-grade Glioma.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2016, Jul-11, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Female; Gl

2016
Early Postoperative Expansion of Parenchymal High-intensity Areas on T2-weighted Imaging Predicts Delayed Cerebral Edema Caused by Carmustine Wafer Implantation in Patients with High-grade Glioma.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2016, Jul-11, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Female; Gl

2016
Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients.
    BMC cancer, 2016, Feb-10, Volume: 16

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carmustine; Combined Modality Therapy; Disease-Free Surv

2016
Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients.
    BMC cancer, 2016, Feb-10, Volume: 16

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carmustine; Combined Modality Therapy; Disease-Free Surv

2016
Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients.
    BMC cancer, 2016, Feb-10, Volume: 16

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carmustine; Combined Modality Therapy; Disease-Free Surv

2016
Patterns of Recurrence After Resection of Malignant Gliomas With BCNU Wafer Implants: Retrospective Review in a Single Institution.
    World neurosurgery, 2016, Volume: 90

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Chemotherapy, Ad

2016
Patterns of Recurrence After Resection of Malignant Gliomas With BCNU Wafer Implants: Retrospective Review in a Single Institution.
    World neurosurgery, 2016, Volume: 90

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Chemotherapy, Ad

2016
Patterns of Recurrence After Resection of Malignant Gliomas With BCNU Wafer Implants: Retrospective Review in a Single Institution.
    World neurosurgery, 2016, Volume: 90

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Chemotherapy, Ad

2016
[Intraoperative BCNU Wafer Implantation for High-Grade Glioma--A Questionnaire Targeting Japanese Neurosurgeons].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Glioma; Humans; Surveys and Question

2016
[Intraoperative BCNU Wafer Implantation for High-Grade Glioma--A Questionnaire Targeting Japanese Neurosurgeons].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Glioma; Humans; Surveys and Question

2016
[Intraoperative BCNU Wafer Implantation for High-Grade Glioma--A Questionnaire Targeting Japanese Neurosurgeons].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Glioma; Humans; Surveys and Question

2016
Eosinophilic meningitis triggered by implanted Gliadel wafers: case report.
    Journal of neurosurgery, 2017, Volume: 126, Issue:6

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Carmustine; Decanoic Acids; Drug Delivery Systems; Dr

2017
Eosinophilic meningitis triggered by implanted Gliadel wafers: case report.
    Journal of neurosurgery, 2017, Volume: 126, Issue:6

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Carmustine; Decanoic Acids; Drug Delivery Systems; Dr

2017
Eosinophilic meningitis triggered by implanted Gliadel wafers: case report.
    Journal of neurosurgery, 2017, Volume: 126, Issue:6

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Carmustine; Decanoic Acids; Drug Delivery Systems; Dr

2017
The influence of carmustine wafer implantation on tumor bed cysts and peritumoral brain edema.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 31

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Cysts; Female; Gl

2016
The influence of carmustine wafer implantation on tumor bed cysts and peritumoral brain edema.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 31

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Cysts; Female; Gl

2016
The influence of carmustine wafer implantation on tumor bed cysts and peritumoral brain edema.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 31

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine; Cysts; Female; Gl

2016
Quantitative analysis of brain edema in patients with malignant glioma treated with BCNU wafers.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 33

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine

2016
Quantitative analysis of brain edema in patients with malignant glioma treated with BCNU wafers.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 33

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine

2016
Quantitative analysis of brain edema in patients with malignant glioma treated with BCNU wafers.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 33

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Carmustine

2016
[Long-Term Efficacy of BCNU Wafers for Malignant Gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2016
[Long-Term Efficacy of BCNU Wafers for Malignant Gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2016
[Long-Term Efficacy of BCNU Wafers for Malignant Gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2016
iRGD-mediated core-shell nanoparticles loading carmustine and O
    Journal of drug targeting, 2017, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line, Tum

2017
iRGD-mediated core-shell nanoparticles loading carmustine and O
    Journal of drug targeting, 2017, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line, Tum

2017
iRGD-mediated core-shell nanoparticles loading carmustine and O
    Journal of drug targeting, 2017, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line, Tum

2017
Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM.
    Science translational medicine, 2016, 12-21, Volume: 8, Issue:370

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Carmu

2016
Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM.
    Science translational medicine, 2016, 12-21, Volume: 8, Issue:370

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Carmu

2016
Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM.
    Science translational medicine, 2016, 12-21, Volume: 8, Issue:370

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Carmu

2016
Noninvasive assessment of E2F-1-mediated transcriptional regulation in vivo.
    Cancer research, 2008, Jul-15, Volume: 68, Issue:14

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Disease Progression; DNA Damage; E2F1 Transc

2008
Noninvasive assessment of E2F-1-mediated transcriptional regulation in vivo.
    Cancer research, 2008, Jul-15, Volume: 68, Issue:14

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Disease Progression; DNA Damage; E2F1 Transc

2008
Noninvasive assessment of E2F-1-mediated transcriptional regulation in vivo.
    Cancer research, 2008, Jul-15, Volume: 68, Issue:14

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Disease Progression; DNA Damage; E2F1 Transc

2008
Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Carmustine; Cell Line, Tumor; Dacarbazi

2008
Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Carmustine; Cell Line, Tumor; Dacarbazi

2008
Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Carmustine; Cell Line, Tumor; Dacarbazi

2008
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Alkylation; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Chromato

2009
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Alkylation; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Chromato

2009
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Alkylation; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Chromato

2009
Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells.
    Biochemical and biophysical research communications, 2009, Feb-06, Volume: 379, Issue:2

    Topics: Acetylation; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Cellular Se

2009
Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells.
    Biochemical and biophysical research communications, 2009, Feb-06, Volume: 379, Issue:2

    Topics: Acetylation; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Cellular Se

2009
Temozolomide and carmustine cause large-scale heterochromatin reorganization in glioma cells.
    Biochemical and biophysical research communications, 2009, Feb-06, Volume: 379, Issue:2

    Topics: Acetylation; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Cellular Se

2009
Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Dose-Response Relati

2009
Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Dose-Response Relati

2009
Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Dose-Response Relati

2009
Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles.
    Technology in cancer research & treatment, 2009, Volume: 8, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Lactic Acid; Male; Nanoparticles; Po

2009
Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles.
    Technology in cancer research & treatment, 2009, Volume: 8, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Lactic Acid; Male; Nanoparticles; Po

2009
Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles.
    Technology in cancer research & treatment, 2009, Volume: 8, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Lactic Acid; Male; Nanoparticles; Po

2009
Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.
    PloS one, 2009, Volume: 4, Issue:2

    Topics: Adenoviridae; Animals; Carmustine; Drug Therapy, Combination; Genetic Therapy; Genetic Vectors; Glio

2009
Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.
    PloS one, 2009, Volume: 4, Issue:2

    Topics: Adenoviridae; Animals; Carmustine; Drug Therapy, Combination; Genetic Therapy; Genetic Vectors; Glio

2009
Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.
    PloS one, 2009, Volume: 4, Issue:2

    Topics: Adenoviridae; Animals; Carmustine; Drug Therapy, Combination; Genetic Therapy; Genetic Vectors; Glio

2009
Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
    Journal of neurosurgery, 2010, Volume: 112, Issue:1

    Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzoquinones; Carmustine; Cell Cycle; Cell L

2010
Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
    Journal of neurosurgery, 2010, Volume: 112, Issue:1

    Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzoquinones; Carmustine; Cell Cycle; Cell L

2010
Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
    Journal of neurosurgery, 2010, Volume: 112, Issue:1

    Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzoquinones; Carmustine; Cell Cycle; Cell L

2010
Incorporating BCNU wafers into malignant glioma treatment: European case studies.
    Clinical drug investigation, 2010, Volume: 30, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2010
Incorporating BCNU wafers into malignant glioma treatment: European case studies.
    Clinical drug investigation, 2010, Volume: 30, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2010
Incorporating BCNU wafers into malignant glioma treatment: European case studies.
    Clinical drug investigation, 2010, Volume: 30, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2010
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
    Neurosurgery, 2010, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Models

2010
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
    Neurosurgery, 2010, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Models

2010
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
    Neurosurgery, 2010, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Models

2010
Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
    Annals of surgical oncology, 2010, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biocompa

2010
Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
    Annals of surgical oncology, 2010, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biocompa

2010
Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
    Annals of surgical oncology, 2010, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biocompa

2010
Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Drug Delivery Syst

2010
Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Drug Delivery Syst

2010
Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Drug Delivery Syst

2010
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
    Journal of experimental & clinical cancer research : CR, 2010, Oct-04, Volume: 29

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain N

2010
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
    Journal of experimental & clinical cancer research : CR, 2010, Oct-04, Volume: 29

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain N

2010
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
    Journal of experimental & clinical cancer research : CR, 2010, Oct-04, Volume: 29

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain N

2010
The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas.
    Biomaterials, 2011, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line; Cell Line, Tumor; Drug Delivery S

2011
The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas.
    Biomaterials, 2011, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line; Cell Line, Tumor; Drug Delivery S

2011
The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas.
    Biomaterials, 2011, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line; Cell Line, Tumor; Drug Delivery S

2011
Earlier detection of tumor treatment response using magnetic resonance diffusion imaging with oscillating gradients.
    Magnetic resonance imaging, 2011, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Diffusion

2011
Earlier detection of tumor treatment response using magnetic resonance diffusion imaging with oscillating gradients.
    Magnetic resonance imaging, 2011, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Diffusion

2011
Earlier detection of tumor treatment response using magnetic resonance diffusion imaging with oscillating gradients.
    Magnetic resonance imaging, 2011, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Diffusion

2011
Space-occupying cyst development in the resection cavity of malignant gliomas following Gliadel® implantation--incidence, therapeutic strategies, and outcome.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Ne

2011
Space-occupying cyst development in the resection cavity of malignant gliomas following Gliadel® implantation--incidence, therapeutic strategies, and outcome.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Ne

2011
Space-occupying cyst development in the resection cavity of malignant gliomas following Gliadel® implantation--incidence, therapeutic strategies, and outcome.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Ne

2011
Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2010
Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2010
Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2010
Pro-apoptotic role of integrin β3 in glioma cells.
    Journal of neurochemistry, 2011, Volume: 117, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Drug Interactio

2011
Pro-apoptotic role of integrin β3 in glioma cells.
    Journal of neurochemistry, 2011, Volume: 117, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Drug Interactio

2011
Pro-apoptotic role of integrin β3 in glioma cells.
    Journal of neurochemistry, 2011, Volume: 117, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Drug Interactio

2011
Heavy chain ferritin siRNA delivered by cationic liposomes increases sensitivity of cancer cells to chemotherapeutic agents.
    Cancer research, 2011, Mar-15, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoferritins; Apoptosis; Blotting, Western; Carmustine;

2011
Heavy chain ferritin siRNA delivered by cationic liposomes increases sensitivity of cancer cells to chemotherapeutic agents.
    Cancer research, 2011, Mar-15, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoferritins; Apoptosis; Blotting, Western; Carmustine;

2011
Heavy chain ferritin siRNA delivered by cationic liposomes increases sensitivity of cancer cells to chemotherapeutic agents.
    Cancer research, 2011, Mar-15, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoferritins; Apoptosis; Blotting, Western; Carmustine;

2011
Carmustine-impregnated wafers and their impact in the management of high-grade glioma.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Carri

2011
Carmustine-impregnated wafers and their impact in the management of high-grade glioma.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Carri

2011
Carmustine-impregnated wafers and their impact in the management of high-grade glioma.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Carri

2011
Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas.
    Biomaterials, 2011, Volume: 32, Issue:27

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Death; Cell Line, Tumor; Computer Simulation; Cross

2011
Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas.
    Biomaterials, 2011, Volume: 32, Issue:27

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Death; Cell Line, Tumor; Computer Simulation; Cross

2011
Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas.
    Biomaterials, 2011, Volume: 32, Issue:27

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Death; Cell Line, Tumor; Computer Simulation; Cross

2011
Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects.
    NMR in biomedicine, 2011, Volume: 24, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Benzenesulfonates; Blood Volume; Carmustine; Cell Death; Cell Line

2011
Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects.
    NMR in biomedicine, 2011, Volume: 24, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Benzenesulfonates; Blood Volume; Carmustine; Cell Death; Cell Line

2011
Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects.
    NMR in biomedicine, 2011, Volume: 24, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Benzenesulfonates; Blood Volume; Carmustine; Cell Death; Cell Line

2011
Knockdown of the potential cancer stem-like cell marker Rex-1 improves chemotherapeutic effects in gliomas.
    Human gene therapy, 2011, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Carmustine; Cell Move

2011
Knockdown of the potential cancer stem-like cell marker Rex-1 improves chemotherapeutic effects in gliomas.
    Human gene therapy, 2011, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Carmustine; Cell Move

2011
Knockdown of the potential cancer stem-like cell marker Rex-1 improves chemotherapeutic effects in gliomas.
    Human gene therapy, 2011, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Carmustine; Cell Move

2011
Inhibition of C6 glioma in vivo by combination chemotherapy of implantation of polymer wafer and intracarotid perfusion of transferrin-decorated nanoparticles.
    Oncology reports, 2012, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

2012
Inhibition of C6 glioma in vivo by combination chemotherapy of implantation of polymer wafer and intracarotid perfusion of transferrin-decorated nanoparticles.
    Oncology reports, 2012, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

2012
Inhibition of C6 glioma in vivo by combination chemotherapy of implantation of polymer wafer and intracarotid perfusion of transferrin-decorated nanoparticles.
    Oncology reports, 2012, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

2012
Silencing of MGMT with small interference RNA reversed resistance in human BCUN-resistant glioma cell lines.
    Chinese medical journal, 2011, Volume: 124, Issue:17

    Topics: Blotting, Western; Carmustine; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glio

2011
Silencing of MGMT with small interference RNA reversed resistance in human BCUN-resistant glioma cell lines.
    Chinese medical journal, 2011, Volume: 124, Issue:17

    Topics: Blotting, Western; Carmustine; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glio

2011
Silencing of MGMT with small interference RNA reversed resistance in human BCUN-resistant glioma cell lines.
    Chinese medical journal, 2011, Volume: 124, Issue:17

    Topics: Blotting, Western; Carmustine; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glio

2011
NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.
    British journal of neurosurgery, 2012, Volume: 26, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Fem

2012
NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.
    British journal of neurosurgery, 2012, Volume: 26, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Fem

2012
NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.
    British journal of neurosurgery, 2012, Volume: 26, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Fem

2012
Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Acrylic Resins; Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Drug Carri

2012
Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Acrylic Resins; Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Drug Carri

2012
Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Acrylic Resins; Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Drug Carri

2012
Concurrent treatment with BCNU and Gamma Knife radiosurgery in the rat malignant glioma model.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Combined

2012
Concurrent treatment with BCNU and Gamma Knife radiosurgery in the rat malignant glioma model.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Combined

2012
Concurrent treatment with BCNU and Gamma Knife radiosurgery in the rat malignant glioma model.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Combined

2012
Induction of β-glucuronidase release by cytostatic agents in small tumors.
    Molecular pharmaceutics, 2012, Nov-05, Volume: 9, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine

2012
Induction of β-glucuronidase release by cytostatic agents in small tumors.
    Molecular pharmaceutics, 2012, Nov-05, Volume: 9, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine

2012
Induction of β-glucuronidase release by cytostatic agents in small tumors.
    Molecular pharmaceutics, 2012, Nov-05, Volume: 9, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine

2012
Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases.
    Annals of surgical oncology, 2013, Volume: 20, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemoradiotherapy, Adjuvant; Dacarbazine

2013
Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases.
    Annals of surgical oncology, 2013, Volume: 20, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemoradiotherapy, Adjuvant; Dacarbazine

2013
Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases.
    Annals of surgical oncology, 2013, Volume: 20, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemoradiotherapy, Adjuvant; Dacarbazine

2013
Antiangiogenic-targeting drug-loaded microbubbles combined with focused ultrasound for glioma treatment.
    Biomaterials, 2013, Volume: 34, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain; Brain Neoplasms

2013
Antiangiogenic-targeting drug-loaded microbubbles combined with focused ultrasound for glioma treatment.
    Biomaterials, 2013, Volume: 34, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain; Brain Neoplasms

2013
Antiangiogenic-targeting drug-loaded microbubbles combined with focused ultrasound for glioma treatment.
    Biomaterials, 2013, Volume: 34, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain; Brain Neoplasms

2013
Growth pattern of tumor recurrence following bis-chloroethylnitrosourea (BCNU) wafer implantation in malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Kaplan-Meier

2013
Growth pattern of tumor recurrence following bis-chloroethylnitrosourea (BCNU) wafer implantation in malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Kaplan-Meier

2013
Growth pattern of tumor recurrence following bis-chloroethylnitrosourea (BCNU) wafer implantation in malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Kaplan-Meier

2013
Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.
    Cancer, 2002, Aug-01, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Deletion; Chromosome

2002
Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.
    Cancer, 2002, Aug-01, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Deletion; Chromosome

2002
Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.
    Cancer, 2002, Aug-01, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Deletion; Chromosome

2002
[Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Carmustine; Cell Cy

2002
[Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Carmustine; Cell Cy

2002
[Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Carmustine; Cell Cy

2002
Camptothecin analogs in malignant gliomas: comparative analysis and characterization.
    Journal of neurosurgery, 2003, Volume: 98, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Camptothecin; Carmust

2003
Camptothecin analogs in malignant gliomas: comparative analysis and characterization.
    Journal of neurosurgery, 2003, Volume: 98, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Camptothecin; Carmust

2003
Camptothecin analogs in malignant gliomas: comparative analysis and characterization.
    Journal of neurosurgery, 2003, Volume: 98, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Camptothecin; Carmust

2003
Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Camptothecin; Carboplatin; Carmustine; Drug Synergis

2003
Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Camptothecin; Carboplatin; Carmustine; Drug Synergis

2003
Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Camptothecin; Carboplatin; Carmustine; Drug Synergis

2003
Formation of DNA adducts and tumor growth delay following intratumoral administration of DTI-015.
    Journal of neuro-oncology, 2003, Volume: 62, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Chromatography, High Pressure Liquid; DNA Ad

2003
Formation of DNA adducts and tumor growth delay following intratumoral administration of DTI-015.
    Journal of neuro-oncology, 2003, Volume: 62, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Chromatography, High Pressure Liquid; DNA Ad

2003
Formation of DNA adducts and tumor growth delay following intratumoral administration of DTI-015.
    Journal of neuro-oncology, 2003, Volume: 62, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Chromatography, High Pressure Liquid; DNA Ad

2003
Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.
    Cancer research, 2003, Jul-15, Volume: 63, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromones; Cisplatin; Drug Synergism; En

2003
Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.
    Cancer research, 2003, Jul-15, Volume: 63, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromones; Cisplatin; Drug Synergism; En

2003
Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.
    Cancer research, 2003, Jul-15, Volume: 63, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromones; Cisplatin; Drug Synergism; En

2003
Gliadel therapy given for first resection of malignant glioma: a single centre study of the potential use of Gliadel.
    British journal of neurosurgery, 2003, Volume: 17, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biocompa

2003
Gliadel therapy given for first resection of malignant glioma: a single centre study of the potential use of Gliadel.
    British journal of neurosurgery, 2003, Volume: 17, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biocompa

2003
Gliadel therapy given for first resection of malignant glioma: a single centre study of the potential use of Gliadel.
    British journal of neurosurgery, 2003, Volume: 17, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biocompa

2003
Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Carmustine; Glioma; Guanin

2003
Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Carmustine; Glioma; Guanin

2003
Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Carmustine; Glioma; Guanin

2003
Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.
    British journal of pharmacology, 2004, Volume: 141, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Cobalt; Def

2004
Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.
    British journal of pharmacology, 2004, Volume: 141, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Cobalt; Def

2004
Carbamoylating chemoresistance induced by cobalt pretreatment in C6 glioma cells: putative roles of hypoxia-inducible factor-1.
    British journal of pharmacology, 2004, Volume: 141, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Cobalt; Def

2004
Advancing the treatment of malignant glioma: act local, think global.
    Cancer investigation, 2004, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Hu

2004
Advancing the treatment of malignant glioma: act local, think global.
    Cancer investigation, 2004, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Hu

2004
Advancing the treatment of malignant glioma: act local, think global.
    Cancer investigation, 2004, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Hu

2004
Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione.
    Free radical biology & medicine, 2004, May-15, Volume: 36, Issue:10

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Carbamates; Carmustine; Chelat

2004
Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione.
    Free radical biology & medicine, 2004, May-15, Volume: 36, Issue:10

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Carbamates; Carmustine; Chelat

2004
Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione.
    Free radical biology & medicine, 2004, May-15, Volume: 36, Issue:10

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Carbamates; Carmustine; Chelat

2004
Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.
    International journal of oncology, 2004, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Carmustine; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; DNA-Binding

2004
Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.
    International journal of oncology, 2004, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Carmustine; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; DNA-Binding

2004
Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.
    International journal of oncology, 2004, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Carmustine; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; DNA-Binding

2004
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Adult; Aged; Alkylating Agents; Brain Neoplasms; Carmustine; CpG Islands; Dacarbazine; DNA; DNA Meth

2004
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Adult; Aged; Alkylating Agents; Brain Neoplasms; Carmustine; CpG Islands; Dacarbazine; DNA; DNA Meth

2004
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Adult; Aged; Alkylating Agents; Brain Neoplasms; Carmustine; CpG Islands; Dacarbazine; DNA; DNA Meth

2004
Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Animals; Anti-Infective Agents, Local; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Ant

2004
Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Animals; Anti-Infective Agents, Local; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Ant

2004
Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Animals; Anti-Infective Agents, Local; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Ant

2004
Therapeutic efficacy of DTI-015 using diffusion magnetic resonance imaging as an early surrogate marker.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Diffusio

2004
Therapeutic efficacy of DTI-015 using diffusion magnetic resonance imaging as an early surrogate marker.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Diffusio

2004
Therapeutic efficacy of DTI-015 using diffusion magnetic resonance imaging as an early surrogate marker.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Diffusio

2004
Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-15, Volume: 10, Issue:24

    Topics: Adenoviridae; Adenovirus E1A Proteins; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2004
Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-15, Volume: 10, Issue:24

    Topics: Adenoviridae; Adenovirus E1A Proteins; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2004
Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-15, Volume: 10, Issue:24

    Topics: Adenoviridae; Adenovirus E1A Proteins; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2004
Cerebral edema associated with Gliadel wafers: two case studies.
    Neuro-oncology, 2005, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Edema; Brain Neoplasms; Carmustine

2005
Cerebral edema associated with Gliadel wafers: two case studies.
    Neuro-oncology, 2005, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Edema; Brain Neoplasms; Carmustine

2005
Cerebral edema associated with Gliadel wafers: two case studies.
    Neuro-oncology, 2005, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Edema; Brain Neoplasms; Carmustine

2005
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Dam

2005
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Dam

2005
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Dam

2005
S-nitrosoglutathione and hypoxia-inducible factor-1 confer chemoresistance against carbamoylating cytotoxicity of BCNU in rat C6 glioma cells.
    Annals of the New York Academy of Sciences, 2005, Volume: 1042

    Topics: Animals; Carmustine; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Hypoxia-Inducible Factor 1

2005
S-nitrosoglutathione and hypoxia-inducible factor-1 confer chemoresistance against carbamoylating cytotoxicity of BCNU in rat C6 glioma cells.
    Annals of the New York Academy of Sciences, 2005, Volume: 1042

    Topics: Animals; Carmustine; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Hypoxia-Inducible Factor 1

2005
S-nitrosoglutathione and hypoxia-inducible factor-1 confer chemoresistance against carbamoylating cytotoxicity of BCNU in rat C6 glioma cells.
    Annals of the New York Academy of Sciences, 2005, Volume: 1042

    Topics: Animals; Carmustine; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Hypoxia-Inducible Factor 1

2005
Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Proliferation

2005
Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Proliferation

2005
Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Proliferation

2005
Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor--a pharmacokinetic study.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Carmustine; Ethanol;

2005
Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor--a pharmacokinetic study.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Carmustine; Ethanol;

2005
Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor--a pharmacokinetic study.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Carmustine; Ethanol;

2005
Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cannabinoids; Carmustine; Cell Line, Tumor; Dronabi

2006
Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cannabinoids; Carmustine; Cell Line, Tumor; Dronabi

2006
Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cannabinoids; Carmustine; Cell Line, Tumor; Dronabi

2006
Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    BMC cancer, 2006, Jan-04, Volume: 6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Survival; Chromosomes, H

2006
Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    BMC cancer, 2006, Jan-04, Volume: 6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Survival; Chromosomes, H

2006
Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    BMC cancer, 2006, Jan-04, Volume: 6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Survival; Chromosomes, H

2006
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
    Journal of neurochemistry, 2006, Volume: 96, Issue:3

    Topics: Antineoplastic Agents, Alkylating; bcl-X Protein; Carmustine; Cell Death; Cell Line, Tumor; Cell Sur

2006
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
    Journal of neurochemistry, 2006, Volume: 96, Issue:3

    Topics: Antineoplastic Agents, Alkylating; bcl-X Protein; Carmustine; Cell Death; Cell Line, Tumor; Cell Sur

2006
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
    Journal of neurochemistry, 2006, Volume: 96, Issue:3

    Topics: Antineoplastic Agents, Alkylating; bcl-X Protein; Carmustine; Cell Death; Cell Line, Tumor; Cell Sur

2006
Interstitial transfer factor as adjuvant immunotherapy for experimental glioma.
    Journal of experimental & clinical cancer research : CR, 2005, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carmustine; Cell Line, Tumor

2005
Interstitial transfer factor as adjuvant immunotherapy for experimental glioma.
    Journal of experimental & clinical cancer research : CR, 2005, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carmustine; Cell Line, Tumor

2005
Interstitial transfer factor as adjuvant immunotherapy for experimental glioma.
    Journal of experimental & clinical cancer research : CR, 2005, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carmustine; Cell Line, Tumor

2005
Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Absorbable Implants; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmu

2006
Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Absorbable Implants; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmu

2006
Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Absorbable Implants; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmu

2006
Dynamic imaging of emerging resistance during cancer therapy.
    Cancer research, 2006, May-01, Volume: 66, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Diffusion Magnetic Resonance Imaging; Drug Administration Sche

2006
Dynamic imaging of emerging resistance during cancer therapy.
    Cancer research, 2006, May-01, Volume: 66, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Diffusion Magnetic Resonance Imaging; Drug Administration Sche

2006
Dynamic imaging of emerging resistance during cancer therapy.
    Cancer research, 2006, May-01, Volume: 66, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Diffusion Magnetic Resonance Imaging; Drug Administration Sche

2006
Predicting and monitoring response to chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea in subcutaneously implanted 9L glioma using the apparent diffusion coefficient of water and 23Na MRI.
    Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Glioma; Magnetic Resonance

2006
Predicting and monitoring response to chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea in subcutaneously implanted 9L glioma using the apparent diffusion coefficient of water and 23Na MRI.
    Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Glioma; Magnetic Resonance

2006
Predicting and monitoring response to chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea in subcutaneously implanted 9L glioma using the apparent diffusion coefficient of water and 23Na MRI.
    Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Glioma; Magnetic Resonance

2006
Role of p16 and p14ARF in radio- and chemosensitivity of malignant gliomas.
    Oncology reports, 2006, Volume: 16, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carmustine; C

2006
Role of p16 and p14ARF in radio- and chemosensitivity of malignant gliomas.
    Oncology reports, 2006, Volume: 16, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carmustine; C

2006
Role of p16 and p14ARF in radio- and chemosensitivity of malignant gliomas.
    Oncology reports, 2006, Volume: 16, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carmustine; C

2006
BCNU-loaded PEG-PLLA ultrafine fibers and their in vitro antitumor activity against Glioma C6 cells.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Sep-12, Volume: 114, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Drug Carrie

2006
BCNU-loaded PEG-PLLA ultrafine fibers and their in vitro antitumor activity against Glioma C6 cells.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Sep-12, Volume: 114, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Drug Carrie

2006
BCNU-loaded PEG-PLLA ultrafine fibers and their in vitro antitumor activity against Glioma C6 cells.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Sep-12, Volume: 114, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Drug Carrie

2006
In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member

2006
In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member

2006
In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member

2006
Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.
    BMC complementary and alternative medicine, 2006, Aug-16, Volume: 6

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Proliferation; Cell Survival; Drug Therapy,

2006
Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.
    BMC complementary and alternative medicine, 2006, Aug-16, Volume: 6

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Proliferation; Cell Survival; Drug Therapy,

2006
Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.
    BMC complementary and alternative medicine, 2006, Aug-16, Volume: 6

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Proliferation; Cell Survival; Drug Therapy,

2006
Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas.
    Cancer, 2006, Nov-15, Volume: 107, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Caspases; Cell Survival; Chemotherap

2006
Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas.
    Cancer, 2006, Nov-15, Volume: 107, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Caspases; Cell Survival; Chemotherap

2006
Cotreatment with a novel phosphoinositide analogue inhibitor and carmustine enhances chemotherapeutic efficacy by attenuating AKT activity in gliomas.
    Cancer, 2006, Nov-15, Volume: 107, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Caspases; Cell Survival; Chemotherap

2006
CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylamines; Brain Neoplasms; C

2006
CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylamines; Brain Neoplasms; C

2006
CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylamines; Brain Neoplasms; C

2006
[Local chemotherapy for brain tumors].
    Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans

2006
[Local chemotherapy for brain tumors].
    Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans

2006
[Local chemotherapy for brain tumors].
    Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans

2006
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2007
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2007
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2007
Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplati

2007
Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplati

2007
Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplati

2007
Imaging response in malignant glioma, RTOG 90-06.
    American journal of clinical oncology, 2007, Volume: 30, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Biopsy; Brain Neoplasms; Carmustine; Disease Progres

2007
Imaging response in malignant glioma, RTOG 90-06.
    American journal of clinical oncology, 2007, Volume: 30, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Biopsy; Brain Neoplasms; Carmustine; Disease Progres

2007
Imaging response in malignant glioma, RTOG 90-06.
    American journal of clinical oncology, 2007, Volume: 30, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Biopsy; Brain Neoplasms; Carmustine; Disease Progres

2007
Cellular and functional characterization of immunoresistant human glioma cell clones selected with alloreactive cytotoxic T lymphocytes reveals their up-regulated synthesis of biologically active TGF-beta.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2007, Volume: 30, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Calcium; Carmustine; Cell Adhesion; C

2007
Cellular and functional characterization of immunoresistant human glioma cell clones selected with alloreactive cytotoxic T lymphocytes reveals their up-regulated synthesis of biologically active TGF-beta.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2007, Volume: 30, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Calcium; Carmustine; Cell Adhesion; C

2007
Cellular and functional characterization of immunoresistant human glioma cell clones selected with alloreactive cytotoxic T lymphocytes reveals their up-regulated synthesis of biologically active TGF-beta.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2007, Volume: 30, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Calcium; Carmustine; Cell Adhesion; C

2007
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Chemokine CCL2; Chemokine CCL2

2008
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Chemokine CCL2; Chemokine CCL2

2008
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Chemokine CCL2; Chemokine CCL2

2008
Carmustine implants for the treatment of newly diagnosed high-grade gliomas: a cost-utility analysis.
    PharmacoEconomics, 2008, Volume: 26, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cohort Studies; Cost-Ben

2008
Carmustine implants for the treatment of newly diagnosed high-grade gliomas: a cost-utility analysis.
    PharmacoEconomics, 2008, Volume: 26, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cohort Studies; Cost-Ben

2008
Carmustine implants for the treatment of newly diagnosed high-grade gliomas: a cost-utility analysis.
    PharmacoEconomics, 2008, Volume: 26, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cohort Studies; Cost-Ben

2008
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms;

2008
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms;

2008
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms;

2008
Age-related chemosensitivity of stem cells from human malignant brain tumours.
    Lancet (London, England), 1982, Apr-17, Volume: 1, Issue:8277

    Topics: Age Factors; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Cell Survival; DNA Repair; Glioblastoma

1982
Age-related chemosensitivity of stem cells from human malignant brain tumours.
    Lancet (London, England), 1982, Apr-17, Volume: 1, Issue:8277

    Topics: Age Factors; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Cell Survival; DNA Repair; Glioblastoma

1982
Age-related chemosensitivity of stem cells from human malignant brain tumours.
    Lancet (London, England), 1982, Apr-17, Volume: 1, Issue:8277

    Topics: Age Factors; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Cell Survival; DNA Repair; Glioblastoma

1982
Post-treatment kinetics of BCNU in a 9L rat brain tumor model.
    Neurologia medico-chirurgica, 1981, Volume: 21, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Kinetics; Male; Neoplasms, Experimental; Rats

1981
Post-treatment kinetics of BCNU in a 9L rat brain tumor model.
    Neurologia medico-chirurgica, 1981, Volume: 21, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Kinetics; Male; Neoplasms, Experimental; Rats

1981
Post-treatment kinetics of BCNU in a 9L rat brain tumor model.
    Neurologia medico-chirurgica, 1981, Volume: 21, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Kinetics; Male; Neoplasms, Experimental; Rats

1981
[High-dose chemotherapy with autologous bone marrow rescue for malignant brain tumors (author's transl)].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Child; Glioma; Huma

1982
[High-dose chemotherapy with autologous bone marrow rescue for malignant brain tumors (author's transl)].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Child; Glioma; Huma

1982
[High-dose chemotherapy with autologous bone marrow rescue for malignant brain tumors (author's transl)].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Child; Glioma; Huma

1982
[Effect of perfluorochemicals on BCNU chemotherapy in a 9L rat brain tumor model].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:10

    Topics: Animals; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorocarbons; Glioma; Male; Neopla

1982
[Effect of perfluorochemicals on BCNU chemotherapy in a 9L rat brain tumor model].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:10

    Topics: Animals; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorocarbons; Glioma; Male; Neopla

1982
[Effect of perfluorochemicals on BCNU chemotherapy in a 9L rat brain tumor model].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:10

    Topics: Animals; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorocarbons; Glioma; Male; Neopla

1982
[Chemotherapy of experimental meningeal gliomatosis].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Carmustine; Glioma; Male;

1984
[Chemotherapy of experimental meningeal gliomatosis].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Carmustine; Glioma; Male;

1984
[Chemotherapy of experimental meningeal gliomatosis].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Carmustine; Glioma; Male;

1984
Interferon as adjuvant therapy with initial radiotherapy of patients with anaplastic gliomas.
    Journal of neurosurgery, 1984, Volume: 61, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Interferons; Mi

1984
Interferon as adjuvant therapy with initial radiotherapy of patients with anaplastic gliomas.
    Journal of neurosurgery, 1984, Volume: 61, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Interferons; Mi

1984
Interferon as adjuvant therapy with initial radiotherapy of patients with anaplastic gliomas.
    Journal of neurosurgery, 1984, Volume: 61, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Interferons; Mi

1984
Treatment of five subcutaneous human glioma tumor lines in athymic mice with carmustine, procarbazine, and mithramycin.
    Cancer treatment reports, 1983, Volume: 67, Issue:9

    Topics: Animals; Carmustine; Disease Models, Animal; Drug Therapy, Combination; Glioma; Humans; Mice; Mice,

1983
Treatment of five subcutaneous human glioma tumor lines in athymic mice with carmustine, procarbazine, and mithramycin.
    Cancer treatment reports, 1983, Volume: 67, Issue:9

    Topics: Animals; Carmustine; Disease Models, Animal; Drug Therapy, Combination; Glioma; Humans; Mice; Mice,

1983
Treatment of five subcutaneous human glioma tumor lines in athymic mice with carmustine, procarbazine, and mithramycin.
    Cancer treatment reports, 1983, Volume: 67, Issue:9

    Topics: Animals; Carmustine; Disease Models, Animal; Drug Therapy, Combination; Glioma; Humans; Mice; Mice,

1983
Biology of gliomas: potential clinical implications of glioma cellular heterogeneity.
    Neurosurgery, 1981, Volume: 9, Issue:3

    Topics: Adult; Aged; Animals; Brain Neoplasms; Carmustine; Cell Line; Female; Glioblastoma; Glioma; Humans;

1981
Biology of gliomas: potential clinical implications of glioma cellular heterogeneity.
    Neurosurgery, 1981, Volume: 9, Issue:3

    Topics: Adult; Aged; Animals; Brain Neoplasms; Carmustine; Cell Line; Female; Glioblastoma; Glioma; Humans;

1981
Biology of gliomas: potential clinical implications of glioma cellular heterogeneity.
    Neurosurgery, 1981, Volume: 9, Issue:3

    Topics: Adult; Aged; Animals; Brain Neoplasms; Carmustine; Cell Line; Female; Glioblastoma; Glioma; Humans;

1981
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Carmustine; Drug Therapy, Combination; Glioma

1982
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Carmustine; Drug Therapy, Combination; Glioma

1982
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Carmustine; Drug Therapy, Combination; Glioma

1982
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
    Neurosurgery, 1982, Volume: 11, Issue:3

    Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma;

1982
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
    Neurosurgery, 1982, Volume: 11, Issue:3

    Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma;

1982
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
    Neurosurgery, 1982, Volume: 11, Issue:3

    Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma;

1982
[Kinetics of multicellular spheroids developed from a human glioblastoma, and effect of 1,3-bis (2-chloroethyl)-1-nitrosourea].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Feb-17, Volume: 59, Issue:7

    Topics: Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Glioma; Humans; Kinetics

1983
[Kinetics of multicellular spheroids developed from a human glioblastoma, and effect of 1,3-bis (2-chloroethyl)-1-nitrosourea].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Feb-17, Volume: 59, Issue:7

    Topics: Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Glioma; Humans; Kinetics

1983
[Kinetics of multicellular spheroids developed from a human glioblastoma, and effect of 1,3-bis (2-chloroethyl)-1-nitrosourea].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Feb-17, Volume: 59, Issue:7

    Topics: Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Glioma; Humans; Kinetics

1983
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study.
    Neurosurgery, 1983, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

1983
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study.
    Neurosurgery, 1983, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

1983
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study.
    Neurosurgery, 1983, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

1983
Megadose chemotherapy with bone marrow rescue.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma

1984
Megadose chemotherapy with bone marrow rescue.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma

1984
Megadose chemotherapy with bone marrow rescue.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma

1984
Feasibility study of combining metronidazole with chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Sq

1983
Feasibility study of combining metronidazole with chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Sq

1983
Feasibility study of combining metronidazole with chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Sq

1983
Combination radiofrequency hyperthermia and chemotherapy (BCNU) for brain malignancy. Animal experience and two case reports.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Chordoma; Combined Modality Therapy; Diathermy; Female; Fronta

1984
Combination radiofrequency hyperthermia and chemotherapy (BCNU) for brain malignancy. Animal experience and two case reports.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Chordoma; Combined Modality Therapy; Diathermy; Female; Fronta

1984
Combination radiofrequency hyperthermia and chemotherapy (BCNU) for brain malignancy. Animal experience and two case reports.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Chordoma; Combined Modality Therapy; Diathermy; Female; Fronta

1984
Complications associated with intra-arterial BCNU administered in combination with vincristine and procarbazine for the treatment of malignant brain tumors.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1984
Complications associated with intra-arterial BCNU administered in combination with vincristine and procarbazine for the treatment of malignant brain tumors.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1984
Complications associated with intra-arterial BCNU administered in combination with vincristine and procarbazine for the treatment of malignant brain tumors.
    Journal of neuro-oncology, 1984, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1984
Heterogeneity of tumor cell DNA content.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Tum

1984
Heterogeneity of tumor cell DNA content.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Tum

1984
Heterogeneity of tumor cell DNA content.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Tum

1984
Combination therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea and low dose rate radiation in the 9L rat brain tumor and spheroid models: implications for brain tumor brachytherapy.
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Animals; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality Therapy; Frontal Lobe; Glioma

1984
Combination therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea and low dose rate radiation in the 9L rat brain tumor and spheroid models: implications for brain tumor brachytherapy.
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Animals; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality Therapy; Frontal Lobe; Glioma

1984
Combination therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea and low dose rate radiation in the 9L rat brain tumor and spheroid models: implications for brain tumor brachytherapy.
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Animals; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality Therapy; Frontal Lobe; Glioma

1984
[Meningeal gliomatosis models as a chemosensitivity assay system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Disease Models, Animal; Dr

1984
[Meningeal gliomatosis models as a chemosensitivity assay system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Disease Models, Animal; Dr

1984
[Meningeal gliomatosis models as a chemosensitivity assay system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Disease Models, Animal; Dr

1984
Malignant anorexia after nitrosourea therapy: case report.
    Neurosurgery, 1984, Volume: 14, Issue:4

    Topics: Adult; Anorexia; Brain Neoplasms; Carmustine; Feeding and Eating Disorders; Glioma; Humans; Male

1984
Malignant anorexia after nitrosourea therapy: case report.
    Neurosurgery, 1984, Volume: 14, Issue:4

    Topics: Adult; Anorexia; Brain Neoplasms; Carmustine; Feeding and Eating Disorders; Glioma; Humans; Male

1984
Malignant anorexia after nitrosourea therapy: case report.
    Neurosurgery, 1984, Volume: 14, Issue:4

    Topics: Adult; Anorexia; Brain Neoplasms; Carmustine; Feeding and Eating Disorders; Glioma; Humans; Male

1984
New therapeutic approaches to treatment of malignant gliomas: chemotherapy and immunotherapy.
    Clinical neurosurgery, 1983, Volume: 31

    Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Blood-Brain Barrier; Brain Neoplasms; C

1983
New therapeutic approaches to treatment of malignant gliomas: chemotherapy and immunotherapy.
    Clinical neurosurgery, 1983, Volume: 31

    Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Blood-Brain Barrier; Brain Neoplasms; C

1983
New therapeutic approaches to treatment of malignant gliomas: chemotherapy and immunotherapy.
    Clinical neurosurgery, 1983, Volume: 31

    Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Blood-Brain Barrier; Brain Neoplasms; C

1983
Human brain tumor xenografts in nude mice as a chemotherapy model.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Humans;

1983
Human brain tumor xenografts in nude mice as a chemotherapy model.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Humans;

1983
Human brain tumor xenografts in nude mice as a chemotherapy model.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Humans;

1983
Intracerebral growth of a human glioma tumor line in athymic mice and treatment with procarbazine, 1,3-bis(2-chloroethyl)-1-nitrosourea, aziridinylbenzoquinone, and cis-platinum.
    Neurosurgery, 1983, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Ce

1983
Intracerebral growth of a human glioma tumor line in athymic mice and treatment with procarbazine, 1,3-bis(2-chloroethyl)-1-nitrosourea, aziridinylbenzoquinone, and cis-platinum.
    Neurosurgery, 1983, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Ce

1983
Intracerebral growth of a human glioma tumor line in athymic mice and treatment with procarbazine, 1,3-bis(2-chloroethyl)-1-nitrosourea, aziridinylbenzoquinone, and cis-platinum.
    Neurosurgery, 1983, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Ce

1983
Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.
    Journal of neurosurgery, 1984, Volume: 61, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intra-Arterial; Male;

1984
Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.
    Journal of neurosurgery, 1984, Volume: 61, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intra-Arterial; Male;

1984
Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.
    Journal of neurosurgery, 1984, Volume: 61, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intra-Arterial; Male;

1984
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationsh

1981
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationsh

1981
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationsh

1981
Improved treatment of a brain-tumor model. Part 2: Sequential therapy with BCNU and 5-fluorouracil.
    Journal of neurosurgery, 1983, Volume: 58, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Clone Cells; Disease Models, Animal; Drug Therapy, Combination

1983
Improved treatment of a brain-tumor model. Part 2: Sequential therapy with BCNU and 5-fluorouracil.
    Journal of neurosurgery, 1983, Volume: 58, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Clone Cells; Disease Models, Animal; Drug Therapy, Combination

1983
Improved treatment of a brain-tumor model. Part 2: Sequential therapy with BCNU and 5-fluorouracil.
    Journal of neurosurgery, 1983, Volume: 58, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Clone Cells; Disease Models, Animal; Drug Therapy, Combination

1983
Stem cell studies of human malignant brain tumors. Part 1: Development of the stem cell assay and its potential.
    Journal of neurosurgery, 1983, Volume: 58, Issue:2

    Topics: Biological Assay; Brain Neoplasms; Carmustine; Clone Cells; Drug Resistance; Glioma; Humans

1983
Stem cell studies of human malignant brain tumors. Part 1: Development of the stem cell assay and its potential.
    Journal of neurosurgery, 1983, Volume: 58, Issue:2

    Topics: Biological Assay; Brain Neoplasms; Carmustine; Clone Cells; Drug Resistance; Glioma; Humans

1983
Stem cell studies of human malignant brain tumors. Part 1: Development of the stem cell assay and its potential.
    Journal of neurosurgery, 1983, Volume: 58, Issue:2

    Topics: Biological Assay; Brain Neoplasms; Carmustine; Clone Cells; Drug Resistance; Glioma; Humans

1983
Solvent systems for intracarotid 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) infusion.
    Neurosurgery, 1983, Volume: 12, Issue:5

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Infusions, Intra-Arterial; Osmolar Concentration; Solub

1983
Solvent systems for intracarotid 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) infusion.
    Neurosurgery, 1983, Volume: 12, Issue:5

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Infusions, Intra-Arterial; Osmolar Concentration; Solub

1983
Solvent systems for intracarotid 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) infusion.
    Neurosurgery, 1983, Volume: 12, Issue:5

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Infusions, Intra-Arterial; Osmolar Concentration; Solub

1983
Radiation and drug response of the rat glioma RG2.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Glioma; Male; Neopl

1982
Radiation and drug response of the rat glioma RG2.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Glioma; Male; Neopl

1982
Radiation and drug response of the rat glioma RG2.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:9

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Glioma; Male; Neopl

1982
Rational planning of brain tumour therapy based on laboratory investigations: comparison of single- and multiple-dose BCNU schedules.
    The British journal of cancer. Supplement, 1980, Volume: 4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Administration Schedule; Glioma; Humans; N

1980
Rational planning of brain tumour therapy based on laboratory investigations: comparison of single- and multiple-dose BCNU schedules.
    The British journal of cancer. Supplement, 1980, Volume: 4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Administration Schedule; Glioma; Humans; N

1980
Rational planning of brain tumour therapy based on laboratory investigations: comparison of single- and multiple-dose BCNU schedules.
    The British journal of cancer. Supplement, 1980, Volume: 4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Administration Schedule; Glioma; Humans; N

1980
Proper analysis of clinical trials for malignant glioma.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Carmustine; Glioma; Humans; Lomustine; Methods; Statistics as Topic

1982
Proper analysis of clinical trials for malignant glioma.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Carmustine; Glioma; Humans; Lomustine; Methods; Statistics as Topic

1982
Proper analysis of clinical trials for malignant glioma.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Carmustine; Glioma; Humans; Lomustine; Methods; Statistics as Topic

1982
Potentiation of carmustine-cranial irradiation-induced myelosuppression by cimetidine.
    Archives of internal medicine, 1982, Volume: 142, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cimetidine; Drug Synergism; Female; Glioma; Guanidines; He

1982
Potentiation of carmustine-cranial irradiation-induced myelosuppression by cimetidine.
    Archives of internal medicine, 1982, Volume: 142, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cimetidine; Drug Synergism; Female; Glioma; Guanidines; He

1982
Potentiation of carmustine-cranial irradiation-induced myelosuppression by cimetidine.
    Archives of internal medicine, 1982, Volume: 142, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cimetidine; Drug Synergism; Female; Glioma; Guanidines; He

1982
Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Glioma; Humans; Medullob

1982
Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Glioma; Humans; Medullob

1982
Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Glioma; Humans; Medullob

1982
Malignant glioma. Results of combined modality therapy.
    JAMA, 1982, Jul-02, Volume: 248, Issue:1

    Topics: Adult; Aged; Anaplasia; Brain; Brain Neoplasms; Carmustine; Glioma; Humans; Middle Aged; Postoperati

1982
Malignant glioma. Results of combined modality therapy.
    JAMA, 1982, Jul-02, Volume: 248, Issue:1

    Topics: Adult; Aged; Anaplasia; Brain; Brain Neoplasms; Carmustine; Glioma; Humans; Middle Aged; Postoperati

1982
Malignant glioma. Results of combined modality therapy.
    JAMA, 1982, Jul-02, Volume: 248, Issue:1

    Topics: Adult; Aged; Anaplasia; Brain; Brain Neoplasms; Carmustine; Glioma; Humans; Middle Aged; Postoperati

1982
Combination carmustine (BCNU) and dianhydrogalactitol in the treatment of primary brain tumors recurring after irradiation.
    Cancer treatment reports, 1982, Volume: 66, Issue:8

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Dianhydrogalactitol; Drug Therapy, Combinatio

1982
Combination carmustine (BCNU) and dianhydrogalactitol in the treatment of primary brain tumors recurring after irradiation.
    Cancer treatment reports, 1982, Volume: 66, Issue:8

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Dianhydrogalactitol; Drug Therapy, Combinatio

1982
Combination carmustine (BCNU) and dianhydrogalactitol in the treatment of primary brain tumors recurring after irradiation.
    Cancer treatment reports, 1982, Volume: 66, Issue:8

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Dianhydrogalactitol; Drug Therapy, Combinatio

1982
Limitations of high dose intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) chemotherapy for malignant gliomas.
    Neurosurgery, 1982, Volume: 10, Issue:6 Pt 1

    Topics: Brain Neoplasms; Carmustine; Carotid Arteries; Female; Glioma; Humans; Infusions, Intra-Arterial; Ma

1982
Limitations of high dose intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) chemotherapy for malignant gliomas.
    Neurosurgery, 1982, Volume: 10, Issue:6 Pt 1

    Topics: Brain Neoplasms; Carmustine; Carotid Arteries; Female; Glioma; Humans; Infusions, Intra-Arterial; Ma

1982
Limitations of high dose intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) chemotherapy for malignant gliomas.
    Neurosurgery, 1982, Volume: 10, Issue:6 Pt 1

    Topics: Brain Neoplasms; Carmustine; Carotid Arteries; Female; Glioma; Humans; Infusions, Intra-Arterial; Ma

1982
[Effect of perfluorochemicals on BCNU chemotherapy in a rat brain-tumor model].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Synergism; Fluorocarbons; Glioma;

1982
[Effect of perfluorochemicals on BCNU chemotherapy in a rat brain-tumor model].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Synergism; Fluorocarbons; Glioma;

1982
[Effect of perfluorochemicals on BCNU chemotherapy in a rat brain-tumor model].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Synergism; Fluorocarbons; Glioma;

1982
Effect of perfluorochemicals on BCNU chemotherapy: preliminary study in a rat brain tumor model.
    Surgical neurology, 1982, Volume: 18, Issue:4

    Topics: Animals; Brain; Brain Neoplasms; Carmustine; Drug Combinations; Drug Therapy, Combination; Fluorocar

1982
Effect of perfluorochemicals on BCNU chemotherapy: preliminary study in a rat brain tumor model.
    Surgical neurology, 1982, Volume: 18, Issue:4

    Topics: Animals; Brain; Brain Neoplasms; Carmustine; Drug Combinations; Drug Therapy, Combination; Fluorocar

1982
Effect of perfluorochemicals on BCNU chemotherapy: preliminary study in a rat brain tumor model.
    Surgical neurology, 1982, Volume: 18, Issue:4

    Topics: Animals; Brain; Brain Neoplasms; Carmustine; Drug Combinations; Drug Therapy, Combination; Fluorocar

1982
Heterogeneous chemosensitivities of subpopulations of human glioma cells in culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Carmustine; Cell Division; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Dose-Res

1982
Heterogeneous chemosensitivities of subpopulations of human glioma cells in culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Carmustine; Cell Division; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Dose-Res

1982
Heterogeneous chemosensitivities of subpopulations of human glioma cells in culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Carmustine; Cell Division; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Dose-Res

1982
The use of cisplatinum for treatment of malignant glioma.
    Medical hypotheses, 1982, Volume: 8, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cisplatin; Glioma; Humans; Male; Middle Aged; Tomography, X-Ray Compute

1982
The use of cisplatinum for treatment of malignant glioma.
    Medical hypotheses, 1982, Volume: 8, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cisplatin; Glioma; Humans; Male; Middle Aged; Tomography, X-Ray Compute

1982
The use of cisplatinum for treatment of malignant glioma.
    Medical hypotheses, 1982, Volume: 8, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cisplatin; Glioma; Humans; Male; Middle Aged; Tomography, X-Ray Compute

1982
Combined cyclotron fast-neutron and BCNU therapy in a rat brain-tumor model.
    Journal of neurosurgery, 1981, Volume: 54, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Dose

1981
Combined cyclotron fast-neutron and BCNU therapy in a rat brain-tumor model.
    Journal of neurosurgery, 1981, Volume: 54, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Dose

1981
Combined cyclotron fast-neutron and BCNU therapy in a rat brain-tumor model.
    Journal of neurosurgery, 1981, Volume: 54, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Dose

1981
1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced pulmonary fibrosis.
    Neurosurgery, 1980, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Lung; Male; Mi

1980
1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced pulmonary fibrosis.
    Neurosurgery, 1980, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Lung; Male; Mi

1980
1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced pulmonary fibrosis.
    Neurosurgery, 1980, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Lung; Male; Mi

1980
Chemosensitivity testing for human brain tumors.
    Progress in clinical and biological research, 1980, Volume: 48

    Topics: Brain Neoplasms; Carmustine; Cell Separation; Cell Survival; Clone Cells; Glioma; Humans

1980
Chemosensitivity testing for human brain tumors.
    Progress in clinical and biological research, 1980, Volume: 48

    Topics: Brain Neoplasms; Carmustine; Cell Separation; Cell Survival; Clone Cells; Glioma; Humans

1980
Chemosensitivity testing for human brain tumors.
    Progress in clinical and biological research, 1980, Volume: 48

    Topics: Brain Neoplasms; Carmustine; Cell Separation; Cell Survival; Clone Cells; Glioma; Humans

1980
Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.
    Journal of neuropathology and experimental neurology, 1981, Volume: 40, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Disease Models, Animal; Glioma; Mice; Mice, Nude; N

1981
Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.
    Journal of neuropathology and experimental neurology, 1981, Volume: 40, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Disease Models, Animal; Glioma; Mice; Mice, Nude; N

1981
Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.
    Journal of neuropathology and experimental neurology, 1981, Volume: 40, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Disease Models, Animal; Glioma; Mice; Mice, Nude; N

1981
Heterogeneous response to chemotherapy of human gliomas grown in nude mice and as clones in vitro.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Clone Cells; Glioma; Humans; Kinetics; Mice; Mice,

1981
Heterogeneous response to chemotherapy of human gliomas grown in nude mice and as clones in vitro.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Clone Cells; Glioma; Humans; Kinetics; Mice; Mice,

1981
Heterogeneous response to chemotherapy of human gliomas grown in nude mice and as clones in vitro.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Clone Cells; Glioma; Humans; Kinetics; Mice; Mice,

1981
Potentials and limitations of a clonogenic cell assay for human brain tumors.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cells, Cultured; Clone Cells; Dose-Response Relationship,

1981
Potentials and limitations of a clonogenic cell assay for human brain tumors.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cells, Cultured; Clone Cells; Dose-Response Relationship,

1981
Potentials and limitations of a clonogenic cell assay for human brain tumors.
    Cancer treatment reports, 1981, Volume: 65 Suppl 2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cells, Cultured; Clone Cells; Dose-Response Relationship,

1981
Prediction of BCNU pulmonary toxicity in patients with malignant gliomas: an assessment of risk factors.
    The New England journal of medicine, 1980, Jul-24, Volume: 303, Issue:4

    Topics: Adult; Analysis of Variance; Bone Marrow; Carmustine; Child; Drug Therapy, Combination; Female; Glio

1980
Prediction of BCNU pulmonary toxicity in patients with malignant gliomas: an assessment of risk factors.
    The New England journal of medicine, 1980, Jul-24, Volume: 303, Issue:4

    Topics: Adult; Analysis of Variance; Bone Marrow; Carmustine; Child; Drug Therapy, Combination; Female; Glio

1980
Prediction of BCNU pulmonary toxicity in patients with malignant gliomas: an assessment of risk factors.
    The New England journal of medicine, 1980, Jul-24, Volume: 303, Issue:4

    Topics: Adult; Analysis of Variance; Bone Marrow; Carmustine; Child; Drug Therapy, Combination; Female; Glio

1980
Treatment of autochthonous rat brain tumors with fractionated radiotherapy. The effects of graded radiation doses and of combined therapy with BCNU or steroids.
    Journal of neurosurgery, 1980, Volume: 53, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Methylprednisolone; Neoplasms,

1980
Treatment of autochthonous rat brain tumors with fractionated radiotherapy. The effects of graded radiation doses and of combined therapy with BCNU or steroids.
    Journal of neurosurgery, 1980, Volume: 53, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Methylprednisolone; Neoplasms,

1980
Treatment of autochthonous rat brain tumors with fractionated radiotherapy. The effects of graded radiation doses and of combined therapy with BCNU or steroids.
    Journal of neurosurgery, 1980, Volume: 53, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Methylprednisolone; Neoplasms,

1980
Response of cultured human brain tumors to nitrosoureas: correlation with clinical data.
    Cancer, 1981, Jan-15, Volume: 47, Issue:2

    Topics: Adult; Brain Neoplasms; Carmustine; Cells, Cultured; Drug Evaluation, Preclinical; Female; Glioma; H

1981
Response of cultured human brain tumors to nitrosoureas: correlation with clinical data.
    Cancer, 1981, Jan-15, Volume: 47, Issue:2

    Topics: Adult; Brain Neoplasms; Carmustine; Cells, Cultured; Drug Evaluation, Preclinical; Female; Glioma; H

1981
Response of cultured human brain tumors to nitrosoureas: correlation with clinical data.
    Cancer, 1981, Jan-15, Volume: 47, Issue:2

    Topics: Adult; Brain Neoplasms; Carmustine; Cells, Cultured; Drug Evaluation, Preclinical; Female; Glioma; H

1981
Effect of pharmacologic doses of zinc on the therapeutic index of brain tumor chemotherapy with carmustine.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Cell Division; Dose-Response Relationship, Drug;

1994
Effect of pharmacologic doses of zinc on the therapeutic index of brain tumor chemotherapy with carmustine.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Cell Division; Dose-Response Relationship, Drug;

1994
Effect of pharmacologic doses of zinc on the therapeutic index of brain tumor chemotherapy with carmustine.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Cell Division; Dose-Response Relationship, Drug;

1994
Contribution of O6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor-derived cell lines.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:2

    Topics: Brain Neoplasms; Carmustine; Cell Adhesion; Colonic Neoplasms; Culture Media; Drug Resistance; Drug

1995
Contribution of O6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor-derived cell lines.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:2

    Topics: Brain Neoplasms; Carmustine; Cell Adhesion; Colonic Neoplasms; Culture Media; Drug Resistance; Drug

1995
Contribution of O6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor-derived cell lines.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:2

    Topics: Brain Neoplasms; Carmustine; Cell Adhesion; Colonic Neoplasms; Culture Media; Drug Resistance; Drug

1995
O6-methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1995, Volume: 22, Issue:2

    Topics: Adult; Animals; Astrocytes; Brain Neoplasms; Carmustine; Cell Differentiation; Cell Survival; Female

1995
O6-methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1995, Volume: 22, Issue:2

    Topics: Adult; Animals; Astrocytes; Brain Neoplasms; Carmustine; Cell Differentiation; Cell Survival; Female

1995
O6-methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1995, Volume: 22, Issue:2

    Topics: Adult; Animals; Astrocytes; Brain Neoplasms; Carmustine; Cell Differentiation; Cell Survival; Female

1995
Formation and repair of 1,3-bis-(2-chloroethyl)-1-nitrosourea and cisplatin induced total genomic DNA interstrand crosslinks in human glioma cells.
    Cancer biochemistry biophysics, 1995, Volume: 14, Issue:4

    Topics: Carmustine; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resi

1995
Formation and repair of 1,3-bis-(2-chloroethyl)-1-nitrosourea and cisplatin induced total genomic DNA interstrand crosslinks in human glioma cells.
    Cancer biochemistry biophysics, 1995, Volume: 14, Issue:4

    Topics: Carmustine; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resi

1995
Formation and repair of 1,3-bis-(2-chloroethyl)-1-nitrosourea and cisplatin induced total genomic DNA interstrand crosslinks in human glioma cells.
    Cancer biochemistry biophysics, 1995, Volume: 14, Issue:4

    Topics: Carmustine; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resi

1995
In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin.
    Cancer research, 1995, Feb-01, Volume: 55, Issue:3

    Topics: Animals; Astrocytoma; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA, Neoplasm; Drug Synergis

1995
In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin.
    Cancer research, 1995, Feb-01, Volume: 55, Issue:3

    Topics: Animals; Astrocytoma; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA, Neoplasm; Drug Synergis

1995
In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin.
    Cancer research, 1995, Feb-01, Volume: 55, Issue:3

    Topics: Animals; Astrocytoma; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA, Neoplasm; Drug Synergis

1995
Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclophosphamide; Decanoic Acids; Delay

1995
Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclophosphamide; Decanoic Acids; Delay

1995
Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cyclophosphamide; Decanoic Acids; Delay

1995
Differentiation therapy is potentiated by chemotherapy and hyperthermia in human and canine brain tumor cells in vitro.
    Neurosurgery, 1994, Volume: 34, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Bucladesine; Butyrates; Butyric Acid; Carmustine; C

1994
Differentiation therapy is potentiated by chemotherapy and hyperthermia in human and canine brain tumor cells in vitro.
    Neurosurgery, 1994, Volume: 34, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Bucladesine; Butyrates; Butyric Acid; Carmustine; C

1994
Differentiation therapy is potentiated by chemotherapy and hyperthermia in human and canine brain tumor cells in vitro.
    Neurosurgery, 1994, Volume: 34, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Bucladesine; Butyrates; Butyric Acid; Carmustine; C

1994
Altered cytotoxicity of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in human glioma cell lines SK-MG-1 and SKI-1 correlates with differential transport kinetics.
    Cancer research, 1994, Mar-15, Volume: 54, Issue:6

    Topics: Antineoplastic Agents; Biological Transport; Carmustine; Chromatography, Thin Layer; Glioma; Humans;

1994
Altered cytotoxicity of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in human glioma cell lines SK-MG-1 and SKI-1 correlates with differential transport kinetics.
    Cancer research, 1994, Mar-15, Volume: 54, Issue:6

    Topics: Antineoplastic Agents; Biological Transport; Carmustine; Chromatography, Thin Layer; Glioma; Humans;

1994
Altered cytotoxicity of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in human glioma cell lines SK-MG-1 and SKI-1 correlates with differential transport kinetics.
    Cancer research, 1994, Mar-15, Volume: 54, Issue:6

    Topics: Antineoplastic Agents; Biological Transport; Carmustine; Chromatography, Thin Layer; Glioma; Humans;

1994
Cognitive functioning in long-term survivors of high-grade glioma.
    Journal of neurosurgery, 1994, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cognition; Fem

1994
Cognitive functioning in long-term survivors of high-grade glioma.
    Journal of neurosurgery, 1994, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cognition; Fem

1994
Cognitive functioning in long-term survivors of high-grade glioma.
    Journal of neurosurgery, 1994, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cognition; Fem

1994
Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain.
    Journal of neurosurgery, 1994, Volume: 80, Issue:2

    Topics: Animals; Brain Edema; Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinat

1994
Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain.
    Journal of neurosurgery, 1994, Volume: 80, Issue:2

    Topics: Animals; Brain Edema; Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinat

1994
Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain.
    Journal of neurosurgery, 1994, Volume: 80, Issue:2

    Topics: Animals; Brain Edema; Brain Neoplasms; Carmustine; Decanoic Acids; Dicarboxylic Acids; Drug Combinat

1994
Prognostic factors in malignant gliomas with special reference to intra-arterial chemotherapy.
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Ad

1993
Prognostic factors in malignant gliomas with special reference to intra-arterial chemotherapy.
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Ad

1993
Prognostic factors in malignant gliomas with special reference to intra-arterial chemotherapy.
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Ad

1993
Carmustine toxicity presenting as a lobar infiltrate.
    Chest, 1993, Volume: 104, Issue:1

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Pulmonary Fibrosis; Vital Capacity

1993
Carmustine toxicity presenting as a lobar infiltrate.
    Chest, 1993, Volume: 104, Issue:1

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Pulmonary Fibrosis; Vital Capacity

1993
Carmustine toxicity presenting as a lobar infiltrate.
    Chest, 1993, Volume: 104, Issue:1

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Pulmonary Fibrosis; Vital Capacity

1993
Transport of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in the human glioma cell line SK-MG-1 is mediated by an epinephrine-sensitive carrier system.
    Molecular pharmacology, 1993, Volume: 44, Issue:1

    Topics: Antineoplastic Agents; Biological Transport; Carmustine; Epinephrine; Glioma; Humans; Sodium; Temper

1993
Transport of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in the human glioma cell line SK-MG-1 is mediated by an epinephrine-sensitive carrier system.
    Molecular pharmacology, 1993, Volume: 44, Issue:1

    Topics: Antineoplastic Agents; Biological Transport; Carmustine; Epinephrine; Glioma; Humans; Sodium; Temper

1993
Transport of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in the human glioma cell line SK-MG-1 is mediated by an epinephrine-sensitive carrier system.
    Molecular pharmacology, 1993, Volume: 44, Issue:1

    Topics: Antineoplastic Agents; Biological Transport; Carmustine; Epinephrine; Glioma; Humans; Sodium; Temper

1993
Comparison between BCNU and procarbazine chemotherapy for treatment of gliomas.
    Journal of neuro-oncology, 1993, Volume: 15, Issue:3

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Procarbazine

1993
Comparison between BCNU and procarbazine chemotherapy for treatment of gliomas.
    Journal of neuro-oncology, 1993, Volume: 15, Issue:3

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Procarbazine

1993
Comparison between BCNU and procarbazine chemotherapy for treatment of gliomas.
    Journal of neuro-oncology, 1993, Volume: 15, Issue:3

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Procarbazine

1993
Interstitial chemotherapy of the 9L gliosarcoma: controlled release polymers for drug delivery in the brain.
    Cancer research, 1993, Jan-15, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Glioma; Ma

1993
Interstitial chemotherapy of the 9L gliosarcoma: controlled release polymers for drug delivery in the brain.
    Cancer research, 1993, Jan-15, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Glioma; Ma

1993
Interstitial chemotherapy of the 9L gliosarcoma: controlled release polymers for drug delivery in the brain.
    Cancer research, 1993, Jan-15, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Delayed-Action Preparations; Glioma; Ma

1993
Oxidative stress in a clonal cell line of neuronal origin: effects of antioxidant enzyme modulation.
    Journal of neurochemistry, 1993, Volume: 60, Issue:6

    Topics: Animals; Brain; Carmustine; Catalase; Cell Fractionation; Cell Survival; Clone Cells; Cytosol; Gliom

1993
Oxidative stress in a clonal cell line of neuronal origin: effects of antioxidant enzyme modulation.
    Journal of neurochemistry, 1993, Volume: 60, Issue:6

    Topics: Animals; Brain; Carmustine; Catalase; Cell Fractionation; Cell Survival; Clone Cells; Cytosol; Gliom

1993
Oxidative stress in a clonal cell line of neuronal origin: effects of antioxidant enzyme modulation.
    Journal of neurochemistry, 1993, Volume: 60, Issue:6

    Topics: Animals; Brain; Carmustine; Catalase; Cell Fractionation; Cell Survival; Clone Cells; Cytosol; Gliom

1993
Identification of a 116 kDa protein able to bind 1,3-bis(2-chloroethyl)-1-nitrosourea-damaged DNA as poly(ADP-ribose) polymerase.
    Mutation research, 1996, Jan-02, Volume: 362, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Southern; Blotting, Western; Carmustine; DNA Damage; DN

1996
Identification of a 116 kDa protein able to bind 1,3-bis(2-chloroethyl)-1-nitrosourea-damaged DNA as poly(ADP-ribose) polymerase.
    Mutation research, 1996, Jan-02, Volume: 362, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Southern; Blotting, Western; Carmustine; DNA Damage; DN

1996
Identification of a 116 kDa protein able to bind 1,3-bis(2-chloroethyl)-1-nitrosourea-damaged DNA as poly(ADP-ribose) polymerase.
    Mutation research, 1996, Jan-02, Volume: 362, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Southern; Blotting, Western; Carmustine; DNA Damage; DN

1996
The sequential changes in DNA synthesis, glucose utilization, protein synthesis, and peripheral benzodiazepine receptor density in C6 brain tumors after chemotherapy to predict the response of tumors to chemotherapy.
    Cancer, 1996, Mar-15, Volume: 77, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Bromodeoxyuridine; Carmustine; DNA; Fem

1996
The sequential changes in DNA synthesis, glucose utilization, protein synthesis, and peripheral benzodiazepine receptor density in C6 brain tumors after chemotherapy to predict the response of tumors to chemotherapy.
    Cancer, 1996, Mar-15, Volume: 77, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Bromodeoxyuridine; Carmustine; DNA; Fem

1996
The sequential changes in DNA synthesis, glucose utilization, protein synthesis, and peripheral benzodiazepine receptor density in C6 brain tumors after chemotherapy to predict the response of tumors to chemotherapy.
    Cancer, 1996, Mar-15, Volume: 77, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Bromodeoxyuridine; Carmustine; DNA; Fem

1996
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Buthionine Sulfoximine; Carmustine; Cell Survival;

1996
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Buthionine Sulfoximine; Carmustine; Cell Survival;

1996
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Buthionine Sulfoximine; Carmustine; Cell Survival;

1996
Characterization of the catecholamine extraneuronal uptake2 carrier in human glioma cell lines SK-MG-1 and SKI-1 in relation to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) selective cytotoxicity.
    Biochemical pharmacology, 1996, Jun-28, Volume: 51, Issue:12

    Topics: Antineoplastic Agents; Carmustine; Catecholamines; Cell Line; Dose-Response Relationship, Drug; Epin

1996
Characterization of the catecholamine extraneuronal uptake2 carrier in human glioma cell lines SK-MG-1 and SKI-1 in relation to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) selective cytotoxicity.
    Biochemical pharmacology, 1996, Jun-28, Volume: 51, Issue:12

    Topics: Antineoplastic Agents; Carmustine; Catecholamines; Cell Line; Dose-Response Relationship, Drug; Epin

1996
Characterization of the catecholamine extraneuronal uptake2 carrier in human glioma cell lines SK-MG-1 and SKI-1 in relation to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) selective cytotoxicity.
    Biochemical pharmacology, 1996, Jun-28, Volume: 51, Issue:12

    Topics: Antineoplastic Agents; Carmustine; Catecholamines; Cell Line; Dose-Response Relationship, Drug; Epin

1996
Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.
    British journal of cancer, 1996, Volume: 74, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Su

1996
Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.
    British journal of cancer, 1996, Volume: 74, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Su

1996
Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.
    British journal of cancer, 1996, Volume: 74, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Su

1996
Computer-assisted microscope characterization of BCNU-induced modifications in the collective behavior of 12 human brain cancer cell lines.
    Journal of neuro-oncology, 1996, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Carcinogens; Carmustine; Cell Count; Cell Death; Cell Division; Cell Survival; Colo

1996
Computer-assisted microscope characterization of BCNU-induced modifications in the collective behavior of 12 human brain cancer cell lines.
    Journal of neuro-oncology, 1996, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Carcinogens; Carmustine; Cell Count; Cell Death; Cell Division; Cell Survival; Colo

1996
Computer-assisted microscope characterization of BCNU-induced modifications in the collective behavior of 12 human brain cancer cell lines.
    Journal of neuro-oncology, 1996, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Carcinogens; Carmustine; Cell Count; Cell Death; Cell Division; Cell Survival; Colo

1996
Intrathecal chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea encapsulated into hybrid liposomes for meningeal gliomatosis: an experimental study.
    Cancer research, 1996, Sep-01, Volume: 56, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dogs; Drug Carriers; Glioma;

1996
Intrathecal chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea encapsulated into hybrid liposomes for meningeal gliomatosis: an experimental study.
    Cancer research, 1996, Sep-01, Volume: 56, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dogs; Drug Carriers; Glioma;

1996
Intrathecal chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea encapsulated into hybrid liposomes for meningeal gliomatosis: an experimental study.
    Cancer research, 1996, Sep-01, Volume: 56, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dogs; Drug Carriers; Glioma;

1996
Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN-01, a selective protein kinase C inhibitor.
    Journal of neurosurgery, 1996, Volume: 84, Issue:6

    Topics: Alkaloids; Brain Neoplasms; Carmustine; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibito

1996
Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN-01, a selective protein kinase C inhibitor.
    Journal of neurosurgery, 1996, Volume: 84, Issue:6

    Topics: Alkaloids; Brain Neoplasms; Carmustine; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibito

1996
Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN-01, a selective protein kinase C inhibitor.
    Journal of neurosurgery, 1996, Volume: 84, Issue:6

    Topics: Alkaloids; Brain Neoplasms; Carmustine; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibito

1996
Quantitative DNA analysis of an intracerebrally transplanted brain tumour model after experimental chemotherapy with BCNU and CCNU.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1995, Volume: 47, Issue:4

    Topics: Animals; Brain Neoplasms; Brain Tissue Transplantation; Carmustine; Cell Division; Cytophotometry; D

1995
Quantitative DNA analysis of an intracerebrally transplanted brain tumour model after experimental chemotherapy with BCNU and CCNU.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1995, Volume: 47, Issue:4

    Topics: Animals; Brain Neoplasms; Brain Tissue Transplantation; Carmustine; Cell Division; Cytophotometry; D

1995
Quantitative DNA analysis of an intracerebrally transplanted brain tumour model after experimental chemotherapy with BCNU and CCNU.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1995, Volume: 47, Issue:4

    Topics: Animals; Brain Neoplasms; Brain Tissue Transplantation; Carmustine; Cell Division; Cytophotometry; D

1995
Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines.
    Journal of neuro-oncology, 1996, Volume: 29, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Car

1996
Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines.
    Journal of neuro-oncology, 1996, Volume: 29, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Car

1996
Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines.
    Journal of neuro-oncology, 1996, Volume: 29, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Car

1996
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Catalase; Cell Divis

1996
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Catalase; Cell Divis

1996
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Catalase; Cell Divis

1996
Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy.
    International journal of cancer, 1996, Oct-21, Volume: 69, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Carmustine; DNA Repair; Glioma; Huma

1996
Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy.
    International journal of cancer, 1996, Oct-21, Volume: 69, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Carmustine; DNA Repair; Glioma; Huma

1996
Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy.
    International journal of cancer, 1996, Oct-21, Volume: 69, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Carmustine; DNA Repair; Glioma; Huma

1996
DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase.
    British journal of cancer, 1997, Volume: 75, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cisplatin; DNA Adducts; DNA, Neoplasm; Drug Scre

1997
DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase.
    British journal of cancer, 1997, Volume: 75, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cisplatin; DNA Adducts; DNA, Neoplasm; Drug Scre

1997
DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase.
    British journal of cancer, 1997, Volume: 75, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cisplatin; DNA Adducts; DNA, Neoplasm; Drug Scre

1997
Visual pathway glioma: an erratic tumour with therapeutic dilemmas.
    Archives of disease in childhood, 1997, Volume: 76, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy

1997
Visual pathway glioma: an erratic tumour with therapeutic dilemmas.
    Archives of disease in childhood, 1997, Volume: 76, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy

1997
Visual pathway glioma: an erratic tumour with therapeutic dilemmas.
    Archives of disease in childhood, 1997, Volume: 76, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy

1997
Advantage of treating anaplastic gliomas with aggressive protocol combining chemotherapy and radiotherapy.
    Journal of neuro-oncology, 1997, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasm

1997
Advantage of treating anaplastic gliomas with aggressive protocol combining chemotherapy and radiotherapy.
    Journal of neuro-oncology, 1997, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasm

1997
Advantage of treating anaplastic gliomas with aggressive protocol combining chemotherapy and radiotherapy.
    Journal of neuro-oncology, 1997, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasm

1997
Survival, prognostic factors, and therapeutic efficacy in low-grade glioma: a retrospective study in 379 patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Child; Chil

1997
Survival, prognostic factors, and therapeutic efficacy in low-grade glioma: a retrospective study in 379 patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Child; Chil

1997
Survival, prognostic factors, and therapeutic efficacy in low-grade glioma: a retrospective study in 379 patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Child; Chil

1997
2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a novel chloroethylnitrosourea analogue with enhanced antitumor activity against human glioma xenografts.
    Cancer research, 1997, Sep-15, Volume: 57, Issue:18

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Carmustine; Drug Administration Sc

1997
2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a novel chloroethylnitrosourea analogue with enhanced antitumor activity against human glioma xenografts.
    Cancer research, 1997, Sep-15, Volume: 57, Issue:18

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Carmustine; Drug Administration Sc

1997
2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a novel chloroethylnitrosourea analogue with enhanced antitumor activity against human glioma xenografts.
    Cancer research, 1997, Sep-15, Volume: 57, Issue:18

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Carmustine; Drug Administration Sc

1997
Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.
    International journal of radiation oncology, biology, physics, 1998, Jan-01, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1998
Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.
    International journal of radiation oncology, biology, physics, 1998, Jan-01, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1998
Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.
    International journal of radiation oncology, biology, physics, 1998, Jan-01, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1998
Preclinical evaluation of 9-chloro-2-methylellipticinium acetate alone and in combination with conventional anticancer drugs for the treatment of human brain tumor xenografts.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1998
Preclinical evaluation of 9-chloro-2-methylellipticinium acetate alone and in combination with conventional anticancer drugs for the treatment of human brain tumor xenografts.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1998
Preclinical evaluation of 9-chloro-2-methylellipticinium acetate alone and in combination with conventional anticancer drugs for the treatment of human brain tumor xenografts.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1998
Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cere

1998
Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cere

1998
Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cere

1998
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:6

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Camptothecin; Carmusti

1998
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:6

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Camptothecin; Carmusti

1998
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:6

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Camptothecin; Carmusti

1998
Excision repair cross-complementing rodent repair deficiency gene 2 expression and chloroethylnitrosourea resistance in human glioma cell lines.
    Neurosurgery, 1998, Volume: 42, Issue:5

    Topics: Brain Neoplasms; Carmustine; Colorimetry; DNA Helicases; DNA Repair; DNA-Binding Proteins; DNA, Neop

1998
Excision repair cross-complementing rodent repair deficiency gene 2 expression and chloroethylnitrosourea resistance in human glioma cell lines.
    Neurosurgery, 1998, Volume: 42, Issue:5

    Topics: Brain Neoplasms; Carmustine; Colorimetry; DNA Helicases; DNA Repair; DNA-Binding Proteins; DNA, Neop

1998
Excision repair cross-complementing rodent repair deficiency gene 2 expression and chloroethylnitrosourea resistance in human glioma cell lines.
    Neurosurgery, 1998, Volume: 42, Issue:5

    Topics: Brain Neoplasms; Carmustine; Colorimetry; DNA Helicases; DNA Repair; DNA-Binding Proteins; DNA, Neop

1998
Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells.
    Journal of neuroimmunology, 1998, Jul-01, Volume: 87, Issue:1-2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Caspase 3; Caspases; Cell Membrane; Cystei

1998
Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells.
    Journal of neuroimmunology, 1998, Jul-01, Volume: 87, Issue:1-2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Caspase 3; Caspases; Cell Membrane; Cystei

1998
Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells.
    Journal of neuroimmunology, 1998, Jul-01, Volume: 87, Issue:1-2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Caspase 3; Caspases; Cell Membrane; Cystei

1998
Chemosensitivity of human malignant glioma: modulation by p53 gene transfer.
    Journal of neuro-oncology, 1998, Volume: 39, Issue:1

    Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Brai

1998
Chemosensitivity of human malignant glioma: modulation by p53 gene transfer.
    Journal of neuro-oncology, 1998, Volume: 39, Issue:1

    Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Brai

1998
Chemosensitivity of human malignant glioma: modulation by p53 gene transfer.
    Journal of neuro-oncology, 1998, Volume: 39, Issue:1

    Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Brai

1998
Malignant glioma: who benefits from adjuvant chemotherapy?
    Annals of neurology, 1998, Volume: 44, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

1998
Malignant glioma: who benefits from adjuvant chemotherapy?
    Annals of neurology, 1998, Volume: 44, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

1998
Malignant glioma: who benefits from adjuvant chemotherapy?
    Annals of neurology, 1998, Volume: 44, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

1998
Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Body Water; Brain Neoplasms; Carmustine; Cell Count; Cel

1997
Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Body Water; Brain Neoplasms; Carmustine; Cell Count; Cel

1997
Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Body Water; Brain Neoplasms; Carmustine; Cell Count; Cel

1997
Growth kinetics and treatment response of the intracerebral rat 9L brain tumor model: a quantitative in vivo study using magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration; Carmustine; Cell Division;

1995
Growth kinetics and treatment response of the intracerebral rat 9L brain tumor model: a quantitative in vivo study using magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration; Carmustine; Cell Division;

1995
Growth kinetics and treatment response of the intracerebral rat 9L brain tumor model: a quantitative in vivo study using magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration; Carmustine; Cell Division;

1995
Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Capillaries; Carmustine; Cell Hypoxia; Dacarbazine; DNA,

1998
Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Capillaries; Carmustine; Cell Hypoxia; Dacarbazine; DNA,

1998
Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Capillaries; Carmustine; Cell Hypoxia; Dacarbazine; DNA,

1998
Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dose-Response Relationship, D

1998
Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dose-Response Relationship, D

1998
Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dose-Response Relationship, D

1998
Beyond the barrier: devices inside the brain.
    Medical device technology, 1995, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans; Neopl

1995
Beyond the barrier: devices inside the brain.
    Medical device technology, 1995, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans; Neopl

1995
Beyond the barrier: devices inside the brain.
    Medical device technology, 1995, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Drug Implants; Glioma; Humans; Neopl

1995
Sensitization of 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin cytotoxicity by 5-bromo-2'-deoxyuridine in human glioma.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Bromodeoxyuridine; Carmustine; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Glioma; Hum

1999
Sensitization of 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin cytotoxicity by 5-bromo-2'-deoxyuridine in human glioma.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Bromodeoxyuridine; Carmustine; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Glioma; Hum

1999
Sensitization of 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin cytotoxicity by 5-bromo-2'-deoxyuridine in human glioma.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Bromodeoxyuridine; Carmustine; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Glioma; Hum

1999
Relationship between drug delivery and the intra-arterial infusion rate of SarCNU in C6 rat brain tumor model.
    Journal of neuro-oncology, 1999, Volume: 41, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoradiography; Brain; Brain Neoplasms; Carmustine; Cell Line; Fema

1999
Relationship between drug delivery and the intra-arterial infusion rate of SarCNU in C6 rat brain tumor model.
    Journal of neuro-oncology, 1999, Volume: 41, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoradiography; Brain; Brain Neoplasms; Carmustine; Cell Line; Fema

1999
Relationship between drug delivery and the intra-arterial infusion rate of SarCNU in C6 rat brain tumor model.
    Journal of neuro-oncology, 1999, Volume: 41, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoradiography; Brain; Brain Neoplasms; Carmustine; Cell Line; Fema

1999
O(6)-methylguanine-DNA methyltransferase gene (MGMT) expression in human glioblastomas in relation to patient characteristics and p53 accumulation.
    International journal of cancer, 1999, Aug-20, Volume: 84, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adj

1999
O(6)-methylguanine-DNA methyltransferase gene (MGMT) expression in human glioblastomas in relation to patient characteristics and p53 accumulation.
    International journal of cancer, 1999, Aug-20, Volume: 84, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adj

1999
O(6)-methylguanine-DNA methyltransferase gene (MGMT) expression in human glioblastomas in relation to patient characteristics and p53 accumulation.
    International journal of cancer, 1999, Aug-20, Volume: 84, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adj

1999
Prolonged inhibition of O(6)-methylguanine DNA methyltransferase in human tumor cells by O(6)-benzylguanine in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Enzyme Inhibitors; Female;

1999
Prolonged inhibition of O(6)-methylguanine DNA methyltransferase in human tumor cells by O(6)-benzylguanine in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Enzyme Inhibitors; Female;

1999
Prolonged inhibition of O(6)-methylguanine DNA methyltransferase in human tumor cells by O(6)-benzylguanine in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Enzyme Inhibitors; Female;

1999
Enhanced antitumor activity of sarCNU in comparison to BCNU in an extraneuronal monoamine transporter positive human glioma xenograft model.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Carmustine; Carrier Proteins; Disease Models, Animal; Drug Screening

1999
Enhanced antitumor activity of sarCNU in comparison to BCNU in an extraneuronal monoamine transporter positive human glioma xenograft model.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Carmustine; Carrier Proteins; Disease Models, Animal; Drug Screening

1999
Enhanced antitumor activity of sarCNU in comparison to BCNU in an extraneuronal monoamine transporter positive human glioma xenograft model.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Carmustine; Carrier Proteins; Disease Models, Animal; Drug Screening

1999
Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status.
    Experimental cell research, 1999, Dec-15, Volume: 253, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain N

1999
Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status.
    Experimental cell research, 1999, Dec-15, Volume: 253, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain N

1999
Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status.
    Experimental cell research, 1999, Dec-15, Volume: 253, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain N

1999
Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Blotting, Western; Buthionine Sulfoximine; Carmustine; Catalase; Fluorescent Antibody Techn

1999
Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Blotting, Western; Buthionine Sulfoximine; Carmustine; Catalase; Fluorescent Antibody Techn

1999
Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Blotting, Western; Buthionine Sulfoximine; Carmustine; Catalase; Fluorescent Antibody Techn

1999
Serial CT and MR imaging of carmustine wafers.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Diseases; Carmustine; Drug Deliver

2000
Serial CT and MR imaging of carmustine wafers.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Diseases; Carmustine; Drug Deliver

2000
Serial CT and MR imaging of carmustine wafers.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Diseases; Carmustine; Drug Deliver

2000
Intracerebral clysis in a rat glioma model.
    Neurosurgery, 2000, Volume: 46, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Dextrans; Drug Deliv

2000
Intracerebral clysis in a rat glioma model.
    Neurosurgery, 2000, Volume: 46, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Dextrans; Drug Deliv

2000
Intracerebral clysis in a rat glioma model.
    Neurosurgery, 2000, Volume: 46, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carmustine; Dextrans; Drug Deliv

2000
Effects of radiation on a model of malignant glioma invasion.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Carmustine; Combined Modality Therapy; Dose-Response

1999
Effects of radiation on a model of malignant glioma invasion.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Carmustine; Combined Modality Therapy; Dose-Response

1999
Effects of radiation on a model of malignant glioma invasion.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Carmustine; Combined Modality Therapy; Dose-Response

1999
Differential effect of cycloheximide on neuronal and glioma cells treated with chemotherapy and radiation.
    Journal of neuro-oncology, 1999, Volume: 45, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Death; Cell Line, Transformed; Cyclohex

1999
Differential effect of cycloheximide on neuronal and glioma cells treated with chemotherapy and radiation.
    Journal of neuro-oncology, 1999, Volume: 45, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Death; Cell Line, Transformed; Cyclohex

1999
Differential effect of cycloheximide on neuronal and glioma cells treated with chemotherapy and radiation.
    Journal of neuro-oncology, 1999, Volume: 45, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Death; Cell Line, Transformed; Cyclohex

1999
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camp

2000
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camp

2000
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camp

2000
An investigation of the cytotoxicity of the morpholino anthracycline MX2 against glioma cells in vitro.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine

2000
An investigation of the cytotoxicity of the morpholino anthracycline MX2 against glioma cells in vitro.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine

2000
An investigation of the cytotoxicity of the morpholino anthracycline MX2 against glioma cells in vitro.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine

2000
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergi

2000
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergi

2000
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergi

2000
Estimating a treatment effect with the accelerated hazards models.
    Controlled clinical trials, 2000, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Hu

2000
Estimating a treatment effect with the accelerated hazards models.
    Controlled clinical trials, 2000, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Hu

2000
Estimating a treatment effect with the accelerated hazards models.
    Controlled clinical trials, 2000, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Hu

2000
Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells.
    Neurochemical research, 2000, Volume: 25, Issue:6

    Topics: Animals; Arylamine N-Acetyltransferase; Brain Neoplasms; Carmustine; DNA Adducts; Fluorenes; Glioma;

2000
Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells.
    Neurochemical research, 2000, Volume: 25, Issue:6

    Topics: Animals; Arylamine N-Acetyltransferase; Brain Neoplasms; Carmustine; DNA Adducts; Fluorenes; Glioma;

2000
Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells.
    Neurochemical research, 2000, Volume: 25, Issue:6

    Topics: Animals; Arylamine N-Acetyltransferase; Brain Neoplasms; Carmustine; DNA Adducts; Fluorenes; Glioma;

2000
Identification of transforming growth factor-beta1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display.
    Cancer, 2000, Aug-15, Volume: 89, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Blotting, Northern; Blotting, Southern; Carmustine; Carrier

2000
Identification of transforming growth factor-beta1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display.
    Cancer, 2000, Aug-15, Volume: 89, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Blotting, Northern; Blotting, Southern; Carmustine; Carrier

2000
Identification of transforming growth factor-beta1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display.
    Cancer, 2000, Aug-15, Volume: 89, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Blotting, Northern; Blotting, Southern; Carmustine; Carrier

2000
Bax expressed from a herpes viral vector enhances the efficacy of N,N'-bis(2-hydroxyethyl)-N-nitrosourea treatment in a rat glioma model.
    Cancer gene therapy, 2000, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Brain Neoplasms; Carmustine;

2000
Bax expressed from a herpes viral vector enhances the efficacy of N,N'-bis(2-hydroxyethyl)-N-nitrosourea treatment in a rat glioma model.
    Cancer gene therapy, 2000, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Brain Neoplasms; Carmustine;

2000
Bax expressed from a herpes viral vector enhances the efficacy of N,N'-bis(2-hydroxyethyl)-N-nitrosourea treatment in a rat glioma model.
    Cancer gene therapy, 2000, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Brain Neoplasms; Carmustine;

2000
Injectable chemotherapeutic microspheres and glioma I: enhanced survival following implantation into the cavity wall of debulked tumors.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Carmustine; Delayed-Action Preparation

2000
Injectable chemotherapeutic microspheres and glioma I: enhanced survival following implantation into the cavity wall of debulked tumors.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Carmustine; Delayed-Action Preparation

2000
Injectable chemotherapeutic microspheres and glioma I: enhanced survival following implantation into the cavity wall of debulked tumors.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Carmustine; Delayed-Action Preparation

2000
Injectable chemotherapeutic microspheres and glioma II: enhanced survival following implantation into deep inoperable tumors.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Carmustine; Corpus Striatum; Delayed-A

2000
Injectable chemotherapeutic microspheres and glioma II: enhanced survival following implantation into deep inoperable tumors.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Carmustine; Corpus Striatum; Delayed-A

2000
Injectable chemotherapeutic microspheres and glioma II: enhanced survival following implantation into deep inoperable tumors.
    Pharmaceutical research, 2000, Volume: 17, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Carmustine; Corpus Striatum; Delayed-A

2000
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2000, Nov-09, Volume: 343, Issue:19

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Disease-Free S

2000
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2000, Nov-09, Volume: 343, Issue:19

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Disease-Free S

2000
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2000, Nov-09, Volume: 343, Issue:19

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Disease-Free S

2000
Pharmacogenomics--teaching old drugs new tricks.
    The New England journal of medicine, 2000, Nov-09, Volume: 343, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; DNA Methylation; DNA, Neoplasm; Gene

2000
Pharmacogenomics--teaching old drugs new tricks.
    The New England journal of medicine, 2000, Nov-09, Volume: 343, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; DNA Methylation; DNA, Neoplasm; Gene

2000
Pharmacogenomics--teaching old drugs new tricks.
    The New England journal of medicine, 2000, Nov-09, Volume: 343, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; DNA Methylation; DNA, Neoplasm; Gene

2000
O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
    Cancer research, 2000, Nov-15, Volume: 60, Issue:22

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2000
O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
    Cancer research, 2000, Nov-15, Volume: 60, Issue:22

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2000
O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
    Cancer research, 2000, Nov-15, Volume: 60, Issue:22

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors.
    Journal of the National Cancer Institute, 2000, Dec-20, Volume: 92, Issue:24

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; C

2000
Detecting treatment-by-centre interaction in multi-centre clinical trials.
    Statistics in medicine, 2001, Jan-30, Volume: 20, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Com

2001
Detecting treatment-by-centre interaction in multi-centre clinical trials.
    Statistics in medicine, 2001, Jan-30, Volume: 20, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Com

2001
Detecting treatment-by-centre interaction in multi-centre clinical trials.
    Statistics in medicine, 2001, Jan-30, Volume: 20, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Com

2001
Altered nuclear localization of bax protein in BCNU-resistant glioma cells.
    Journal of neuro-oncology, 2000, Volume: 49, Issue:2

    Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein;

2000
Altered nuclear localization of bax protein in BCNU-resistant glioma cells.
    Journal of neuro-oncology, 2000, Volume: 49, Issue:2

    Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein;

2000
Altered nuclear localization of bax protein in BCNU-resistant glioma cells.
    Journal of neuro-oncology, 2000, Volume: 49, Issue:2

    Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein;

2000
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Methylation; DNA, Neop

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Methylation; DNA, Neop

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Methylation; DNA, Neop

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Age Distribution; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Meth

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Age Distribution; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Meth

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Age Distribution; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Meth

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Methylation; DN

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Methylation; DN

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality Therapy; DNA Methylation; DN

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Carmustine; DNA Methylation; DNA, Neoplasm; Glioma; Humans; O(6)-

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Carmustine; DNA Methylation; DNA, Neoplasm; Glioma; Humans; O(6)-

2001
The DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Carmustine; DNA Methylation; DNA, Neoplasm; Glioma; Humans; O(6)-

2001
Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2001
Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2001
Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2001
Inducible nitric oxide synthase neutralizes carbamoylating potential of 1,3-bis(2-chloroethyl)-1-nitrosourea in c6 glioma cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antisense Elements (Genetics); Carmustine; Drug Resistan

2001
Inducible nitric oxide synthase neutralizes carbamoylating potential of 1,3-bis(2-chloroethyl)-1-nitrosourea in c6 glioma cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antisense Elements (Genetics); Carmustine; Drug Resistan

2001
Inducible nitric oxide synthase neutralizes carbamoylating potential of 1,3-bis(2-chloroethyl)-1-nitrosourea in c6 glioma cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antisense Elements (Genetics); Carmustine; Drug Resistan

2001
Multimodality program involving stereotactic surgery in brain tumor management.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:3-4

    Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy; Brachytherapy; Brain Neoplasms; Carmustine; Chemot

2000
Multimodality program involving stereotactic surgery in brain tumor management.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:3-4

    Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy; Brachytherapy; Brain Neoplasms; Carmustine; Chemot

2000
Multimodality program involving stereotactic surgery in brain tumor management.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:3-4

    Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy; Brachytherapy; Brain Neoplasms; Carmustine; Chemot

2000
Effects of chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea on single-quantum- and triple-quantum-filtered 23Na and 31P nuclear magnetic resonance of the subcutaneously implanted 9L glioma.
    Cancer research, 2001, Mar-01, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Gli

2001
Effects of chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea on single-quantum- and triple-quantum-filtered 23Na and 31P nuclear magnetic resonance of the subcutaneously implanted 9L glioma.
    Cancer research, 2001, Mar-01, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Gli

2001
Effects of chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea on single-quantum- and triple-quantum-filtered 23Na and 31P nuclear magnetic resonance of the subcutaneously implanted 9L glioma.
    Cancer research, 2001, Mar-01, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Gli

2001
Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter.
    Journal of neuro-oncology, 2001, Volume: 51, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Carr

2001
Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter.
    Journal of neuro-oncology, 2001, Volume: 51, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Carr

2001
Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter.
    Journal of neuro-oncology, 2001, Volume: 51, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Carr

2001
Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase In

2001
Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase In

2001
Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase In

2001
Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.
    International journal of oncology, 2001, Volume: 19, Issue:2

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Proteins; Cell Survival; Cyc

2001
Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.
    International journal of oncology, 2001, Volume: 19, Issue:2

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Proteins; Cell Survival; Cyc

2001
Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.
    International journal of oncology, 2001, Volume: 19, Issue:2

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle Proteins; Cell Survival; Cyc

2001
Accelerated hazards regression model and its adequacy for censored survival data.
    Biometrics, 2001, Volume: 57, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biometry; Brain Neoplasms; Carmustine; Glioma; Humans; Neoplasm R

2001
Accelerated hazards regression model and its adequacy for censored survival data.
    Biometrics, 2001, Volume: 57, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biometry; Brain Neoplasms; Carmustine; Glioma; Humans; Neoplasm R

2001
Accelerated hazards regression model and its adequacy for censored survival data.
    Biometrics, 2001, Volume: 57, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biometry; Brain Neoplasms; Carmustine; Glioma; Humans; Neoplasm R

2001
Quinacrine enhances carmustine therapy of experimental rat glioma.
    Neurosurgery, 2001, Volume: 49, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergis

2001
Quinacrine enhances carmustine therapy of experimental rat glioma.
    Neurosurgery, 2001, Volume: 49, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergis

2001
Quinacrine enhances carmustine therapy of experimental rat glioma.
    Neurosurgery, 2001, Volume: 49, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergis

2001
Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Carmustine; Cisplatin; DNA Damage; Gene Transfer Tec

2002
Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Carmustine; Cisplatin; DNA Damage; Gene Transfer Tec

2002
Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Carmustine; Cisplatin; DNA Damage; Gene Transfer Tec

2002
Injection of chemotherapeutic microspheres and glioma. IV: Eradicating tumors in rats.
    Cell transplantation, 2002, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carboplatin; Car

2002
Injection of chemotherapeutic microspheres and glioma. IV: Eradicating tumors in rats.
    Cell transplantation, 2002, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carboplatin; Car

2002
Injection of chemotherapeutic microspheres and glioma. IV: Eradicating tumors in rats.
    Cell transplantation, 2002, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carboplatin; Car

2002
Single-agent chemotherapy of brain tumors. A five-year review.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carmustine; Glioma; Humans; Imidazoles; Lomustin

1976
Single-agent chemotherapy of brain tumors. A five-year review.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carmustine; Glioma; Humans; Imidazoles; Lomustin

1976
Single-agent chemotherapy of brain tumors. A five-year review.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carmustine; Glioma; Humans; Imidazoles; Lomustin

1976
BCNU-5-fluorouracil combination therapy for recurrent malignant brain tumors.
    Cancer treatment reports, 1978, Volume: 62, Issue:12

    Topics: Astrocytoma; Bone Marrow; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glio

1978
BCNU-5-fluorouracil combination therapy for recurrent malignant brain tumors.
    Cancer treatment reports, 1978, Volume: 62, Issue:12

    Topics: Astrocytoma; Bone Marrow; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glio

1978
BCNU-5-fluorouracil combination therapy for recurrent malignant brain tumors.
    Cancer treatment reports, 1978, Volume: 62, Issue:12

    Topics: Astrocytoma; Bone Marrow; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glio

1978
[Value of chemotherapy associated with conventional treatment of malignant gliomas of the brain. Study of 95 cases with histological verification and follow-up of 1 to 6 years 9 months].
    Revue neurologique, 1979, Volume: 135, Issue:3

    Topics: Administration, Oral; Adult; Brain Neoplasms; Carmustine; Drug Evaluation; Drug Therapy, Combination

1979
[Value of chemotherapy associated with conventional treatment of malignant gliomas of the brain. Study of 95 cases with histological verification and follow-up of 1 to 6 years 9 months].
    Revue neurologique, 1979, Volume: 135, Issue:3

    Topics: Administration, Oral; Adult; Brain Neoplasms; Carmustine; Drug Evaluation; Drug Therapy, Combination

1979
[Value of chemotherapy associated with conventional treatment of malignant gliomas of the brain. Study of 95 cases with histological verification and follow-up of 1 to 6 years 9 months].
    Revue neurologique, 1979, Volume: 135, Issue:3

    Topics: Administration, Oral; Adult; Brain Neoplasms; Carmustine; Drug Evaluation; Drug Therapy, Combination

1979
Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model.
    Journal of neurosurgery, 1979, Volume: 51, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Brain Neoplasms; Carmustine; Glioma; Neoplasms, Experimental; Rats

1979
Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model.
    Journal of neurosurgery, 1979, Volume: 51, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Brain Neoplasms; Carmustine; Glioma; Neoplasms, Experimental; Rats

1979
Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model.
    Journal of neurosurgery, 1979, Volume: 51, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Brain Neoplasms; Carmustine; Glioma; Neoplasms, Experimental; Rats

1979
Neuropathology of tissues from patients treated by the Brain Tumor Study Group.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Adult; Anaplasia; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Necrosis; Radiation Inj

1977
Neuropathology of tissues from patients treated by the Brain Tumor Study Group.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Adult; Anaplasia; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Necrosis; Radiation Inj

1977
Neuropathology of tissues from patients treated by the Brain Tumor Study Group.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Adult; Anaplasia; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Necrosis; Radiation Inj

1977
Treatment of primitive malignant tumors of the central nervous system. Clinical evaluation of 91 cases.
    Acta neurologica, 1979, Volume: 1, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Ependymoma; Glioma; Humans; Lomustine; Oligodendroglioma

1979
Treatment of primitive malignant tumors of the central nervous system. Clinical evaluation of 91 cases.
    Acta neurologica, 1979, Volume: 1, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Ependymoma; Glioma; Humans; Lomustine; Oligodendroglioma

1979
Treatment of primitive malignant tumors of the central nervous system. Clinical evaluation of 91 cases.
    Acta neurologica, 1979, Volume: 1, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Ependymoma; Glioma; Humans; Lomustine; Oligodendroglioma

1979
BCNU and malignant glioma.
    Journal of neurosurgery, 1979, Volume: 50, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Evaluation; Follow-Up Studies; Glioma; Humans

1979
BCNU and malignant glioma.
    Journal of neurosurgery, 1979, Volume: 50, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Evaluation; Follow-Up Studies; Glioma; Humans

1979
BCNU and malignant glioma.
    Journal of neurosurgery, 1979, Volume: 50, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Evaluation; Follow-Up Studies; Glioma; Humans

1979
Desmosterol: a biochemical marker of glioma growth.
    Surgical neurology, 1977, Volume: 8, Issue:6

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Chromatography, Gas; Desmosterol; Diagnosis,

1977
Desmosterol: a biochemical marker of glioma growth.
    Surgical neurology, 1977, Volume: 8, Issue:6

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Chromatography, Gas; Desmosterol; Diagnosis,

1977
Desmosterol: a biochemical marker of glioma growth.
    Surgical neurology, 1977, Volume: 8, Issue:6

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Chromatography, Gas; Desmosterol; Diagnosis,

1977
Variations in response of human brain tumors to BCNU in vitro.
    Journal of neurosurgery, 1978, Volume: 48, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cells, Cultured; Glioma; Humans; Meningeal Neoplasms; Meningioma

1978
Variations in response of human brain tumors to BCNU in vitro.
    Journal of neurosurgery, 1978, Volume: 48, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cells, Cultured; Glioma; Humans; Meningeal Neoplasms; Meningioma

1978
Variations in response of human brain tumors to BCNU in vitro.
    Journal of neurosurgery, 1978, Volume: 48, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cells, Cultured; Glioma; Humans; Meningeal Neoplasms; Meningioma

1978
Combined chemotherapy with VM 26 and BCNU for recurrent malignant gliomas after operation and irradiation.
    Acta neurochirurgica, 1978, Volume: 42, Issue:1-2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Female; Glioma; Humans; Male; M

1978
Combined chemotherapy with VM 26 and BCNU for recurrent malignant gliomas after operation and irradiation.
    Acta neurochirurgica, 1978, Volume: 42, Issue:1-2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Female; Glioma; Humans; Male; M

1978
Combined chemotherapy with VM 26 and BCNU for recurrent malignant gliomas after operation and irradiation.
    Acta neurochirurgica, 1978, Volume: 42, Issue:1-2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Female; Glioma; Humans; Male; M

1978
Where are we heading--heat and otherwise.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Animals; Body Temperature; Brain Neoplasms; Carmustine; Glioma; Hot Temperature; Humans; Radiotherap

1978
Where are we heading--heat and otherwise.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Animals; Body Temperature; Brain Neoplasms; Carmustine; Glioma; Hot Temperature; Humans; Radiotherap

1978
Where are we heading--heat and otherwise.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Animals; Body Temperature; Brain Neoplasms; Carmustine; Glioma; Hot Temperature; Humans; Radiotherap

1978
Immunotherapy of brain tumors--is there a future?
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Antibodies, Neoplasm; BCG Vaccine; Brain Neoplasms; Carmustine; Cytotoxicity, Immunologic; Glioma; H

1978
Immunotherapy of brain tumors--is there a future?
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Antibodies, Neoplasm; BCG Vaccine; Brain Neoplasms; Carmustine; Cytotoxicity, Immunologic; Glioma; H

1978
Immunotherapy of brain tumors--is there a future?
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Antibodies, Neoplasm; BCG Vaccine; Brain Neoplasms; Carmustine; Cytotoxicity, Immunologic; Glioma; H

1978
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Dru

1978
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Dru

1978
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Dru

1978
Radiation therapy of malignant brain tumors.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Animals; Brain Neoplasms; Brain Stem; Carmustine; Ependymoma; Glioma; Humans; Medulloblastoma; Neopl

1978
Radiation therapy of malignant brain tumors.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Animals; Brain Neoplasms; Brain Stem; Carmustine; Ependymoma; Glioma; Humans; Medulloblastoma; Neopl

1978
Radiation therapy of malignant brain tumors.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Animals; Brain Neoplasms; Brain Stem; Carmustine; Ependymoma; Glioma; Humans; Medulloblastoma; Neopl

1978
Surgical therapy of primary malignant brain tumors.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Mid

1978
Surgical therapy of primary malignant brain tumors.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Mid

1978
Surgical therapy of primary malignant brain tumors.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Mid

1978
Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:1

    Topics: Animals; Carmustine; Dianhydrogalactitol; Drug Therapy, Combination; Ellipticines; Glioma; Lomustine

1978
Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:1

    Topics: Animals; Carmustine; Dianhydrogalactitol; Drug Therapy, Combination; Ellipticines; Glioma; Lomustine

1978
Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:1

    Topics: Animals; Carmustine; Dianhydrogalactitol; Drug Therapy, Combination; Ellipticines; Glioma; Lomustine

1978
Combined growth-inhibitory responses and ultrastructural alterations produced by 1,3-bis(2-chloroethyl)-1-nitrosourea and dexamethasone in rat glioma cell cultures.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Drug In

1977
Combined growth-inhibitory responses and ultrastructural alterations produced by 1,3-bis(2-chloroethyl)-1-nitrosourea and dexamethasone in rat glioma cell cultures.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Drug In

1977
Combined growth-inhibitory responses and ultrastructural alterations produced by 1,3-bis(2-chloroethyl)-1-nitrosourea and dexamethasone in rat glioma cell cultures.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Drug In

1977
Brain-tumor therapy. Quantitative analysis using a model system.
    Journal of neurosurgery, 1977, Volume: 46, Issue:2

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

1977
Brain-tumor therapy. Quantitative analysis using a model system.
    Journal of neurosurgery, 1977, Volume: 46, Issue:2

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

1977
Brain-tumor therapy. Quantitative analysis using a model system.
    Journal of neurosurgery, 1977, Volume: 46, Issue:2

    Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

1977
Increased volumes of mitochondria and granular endoplasmic reticulum in rat glioma cells treated with anti-tumor agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 155, Issue:2

    Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Endoplasmic Reticulum; Glioma; Mitochondr

1977
Increased volumes of mitochondria and granular endoplasmic reticulum in rat glioma cells treated with anti-tumor agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 155, Issue:2

    Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Endoplasmic Reticulum; Glioma; Mitochondr

1977
Increased volumes of mitochondria and granular endoplasmic reticulum in rat glioma cells treated with anti-tumor agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 155, Issue:2

    Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Endoplasmic Reticulum; Glioma; Mitochondr

1977
Neurosurgical aspects of supratentorial malignant gliomas.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:1

    Topics: Biopsy; Brain Neoplasms; Carmustine; Craniotomy; Glioma; Methotrexate

1976
Neurosurgical aspects of supratentorial malignant gliomas.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:1

    Topics: Biopsy; Brain Neoplasms; Carmustine; Craniotomy; Glioma; Methotrexate

1976
Neurosurgical aspects of supratentorial malignant gliomas.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:1

    Topics: Biopsy; Brain Neoplasms; Carmustine; Craniotomy; Glioma; Methotrexate

1976
Chemotherapy of brain tumors.
    Advances in neurology, 1976, Volume: 15

    Topics: Brain Neoplasms; Carmustine; Drug Combinations; Glioma; Humans; Lomustine; Methotrexate; Podophyllot

1976
Chemotherapy of brain tumors.
    Advances in neurology, 1976, Volume: 15

    Topics: Brain Neoplasms; Carmustine; Drug Combinations; Glioma; Humans; Lomustine; Methotrexate; Podophyllot

1976
Chemotherapy of brain tumors.
    Advances in neurology, 1976, Volume: 15

    Topics: Brain Neoplasms; Carmustine; Drug Combinations; Glioma; Humans; Lomustine; Methotrexate; Podophyllot

1976
Nitrosourea pharmacodynamics in relation to the central nervous system.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecula

1976
Nitrosourea pharmacodynamics in relation to the central nervous system.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecula

1976
Nitrosourea pharmacodynamics in relation to the central nervous system.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecula

1976
Nitrosourea chemotherapy for primary malignant gliomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neo

1976
Nitrosourea chemotherapy for primary malignant gliomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neo

1976
Nitrosourea chemotherapy for primary malignant gliomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neo

1976
Sterols in cerebrospinal fluid during nitrosourea chemotherapy of human brain tumors.
    Pharmacological research communications, 1976, Volume: 8, Issue:2

    Topics: Adult; Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Desmosterol; Female; Glioma; Humans; I

1976
Sterols in cerebrospinal fluid during nitrosourea chemotherapy of human brain tumors.
    Pharmacological research communications, 1976, Volume: 8, Issue:2

    Topics: Adult; Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Desmosterol; Female; Glioma; Humans; I

1976
Sterols in cerebrospinal fluid during nitrosourea chemotherapy of human brain tumors.
    Pharmacological research communications, 1976, Volume: 8, Issue:2

    Topics: Adult; Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Desmosterol; Female; Glioma; Humans; I

1976
Chemotherapy of primary malignant brain tumors in children.
    Cancer, 1975, Volume: 35, Issue:3 suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carmustine; Child; Ependymoma; Glioma; Humans; M

1975
Chemotherapy of primary malignant brain tumors in children.
    Cancer, 1975, Volume: 35, Issue:3 suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carmustine; Child; Ependymoma; Glioma; Humans; M

1975
Chemotherapy of primary malignant brain tumors in children.
    Cancer, 1975, Volume: 35, Issue:3 suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carmustine; Child; Ependymoma; Glioma; Humans; M

1975
Long-term survival of patients treated with BCNU for brain tumors.
    Journal of neurosurgery, 1975, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Astrocytoma; Bone Marrow; Brain; Brain Neoplasms; Carmustine; Dose-Response Relat

1975
Long-term survival of patients treated with BCNU for brain tumors.
    Journal of neurosurgery, 1975, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Astrocytoma; Bone Marrow; Brain; Brain Neoplasms; Carmustine; Dose-Response Relat

1975
Long-term survival of patients treated with BCNU for brain tumors.
    Journal of neurosurgery, 1975, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Astrocytoma; Bone Marrow; Brain; Brain Neoplasms; Carmustine; Dose-Response Relat

1975
Editorial: Brain tumor. Current status of treatment and its complications.
    Archives of neurology, 1975, Volume: 32, Issue:12

    Topics: Brain Neoplasms; Carcinoma; Carmustine; Glioma; Humans; Meninges; Methotrexate; Neoplasm Metastasis;

1975
Editorial: Brain tumor. Current status of treatment and its complications.
    Archives of neurology, 1975, Volume: 32, Issue:12

    Topics: Brain Neoplasms; Carcinoma; Carmustine; Glioma; Humans; Meninges; Methotrexate; Neoplasm Metastasis;

1975
Editorial: Brain tumor. Current status of treatment and its complications.
    Archives of neurology, 1975, Volume: 32, Issue:12

    Topics: Brain Neoplasms; Carcinoma; Carmustine; Glioma; Humans; Meninges; Methotrexate; Neoplasm Metastasis;

1975
[Effect of pretreatment with N-methyl-N-nitrosourea or streptozotocin on the cytotoxicity and the induction of sister chromatid exchanges in human and rodent brain tumor cells treated with chloroethylnitrosourea].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance; Drug Synergism; Ethylnitrosour

1992
[Effect of pretreatment with N-methyl-N-nitrosourea or streptozotocin on the cytotoxicity and the induction of sister chromatid exchanges in human and rodent brain tumor cells treated with chloroethylnitrosourea].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance; Drug Synergism; Ethylnitrosour

1992
[Effect of pretreatment with N-methyl-N-nitrosourea or streptozotocin on the cytotoxicity and the induction of sister chromatid exchanges in human and rodent brain tumor cells treated with chloroethylnitrosourea].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance; Drug Synergism; Ethylnitrosour

1992
In vitro analysis of the cellular resistance to chemotherapeutic BCNU.
    Histology and histopathology, 1992, Volume: 7, Issue:3

    Topics: Carmustine; Cell Differentiation; Cell Division; Clone Cells; DNA Repair; Dose-Response Relationship

1992
In vitro analysis of the cellular resistance to chemotherapeutic BCNU.
    Histology and histopathology, 1992, Volume: 7, Issue:3

    Topics: Carmustine; Cell Differentiation; Cell Division; Clone Cells; DNA Repair; Dose-Response Relationship

1992
In vitro analysis of the cellular resistance to chemotherapeutic BCNU.
    Histology and histopathology, 1992, Volume: 7, Issue:3

    Topics: Carmustine; Cell Differentiation; Cell Division; Clone Cells; DNA Repair; Dose-Response Relationship

1992
Effect of intra-arterial cisplatin and 1,3-bis(2chloroethyl)-1-nitrosourea (BCNU) dosage on radiographic response and regional toxicity in malignant glioma patients: proposal of a new method of intra-arterial dosage calculation.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cis

1992
Effect of intra-arterial cisplatin and 1,3-bis(2chloroethyl)-1-nitrosourea (BCNU) dosage on radiographic response and regional toxicity in malignant glioma patients: proposal of a new method of intra-arterial dosage calculation.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cis

1992
Effect of intra-arterial cisplatin and 1,3-bis(2chloroethyl)-1-nitrosourea (BCNU) dosage on radiographic response and regional toxicity in malignant glioma patients: proposal of a new method of intra-arterial dosage calculation.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Cis

1992
Metoclopramide as a sensitizer of 1,3-bis(2-chloroethyl)-1-nitrosourea treatment of brain tumors in the rat.
    Anti-cancer drugs, 1992, Volume: 3, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Brain Neoplasms; Carmustine; F

1992
Metoclopramide as a sensitizer of 1,3-bis(2-chloroethyl)-1-nitrosourea treatment of brain tumors in the rat.
    Anti-cancer drugs, 1992, Volume: 3, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Brain Neoplasms; Carmustine; F

1992
Metoclopramide as a sensitizer of 1,3-bis(2-chloroethyl)-1-nitrosourea treatment of brain tumors in the rat.
    Anti-cancer drugs, 1992, Volume: 3, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Brain Neoplasms; Carmustine; F

1992
Maculopathy caused by intra-arterially administered cisplatin and intravenously administered carmustine.
    American journal of ophthalmology, 1992, Apr-15, Volume: 113, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cisplatin; Electrophysiology; Fluorescein Angiography; Fun

1992
Maculopathy caused by intra-arterially administered cisplatin and intravenously administered carmustine.
    American journal of ophthalmology, 1992, Apr-15, Volume: 113, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cisplatin; Electrophysiology; Fluorescein Angiography; Fun

1992
Maculopathy caused by intra-arterially administered cisplatin and intravenously administered carmustine.
    American journal of ophthalmology, 1992, Apr-15, Volume: 113, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Cisplatin; Electrophysiology; Fluorescein Angiography; Fun

1992
Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas.
    Journal of neuro-oncology, 1992, Volume: 12, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cisplatin; Female; Glioma; Humans;

1992
Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas.
    Journal of neuro-oncology, 1992, Volume: 12, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cisplatin; Female; Glioma; Humans;

1992
Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas.
    Journal of neuro-oncology, 1992, Volume: 12, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cisplatin; Female; Glioma; Humans;

1992
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Color

1992
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Color

1992
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Color

1992
Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Anticholesteremic Agents; Carmustine; Cell Count; Cell Division; Culture Media; Dose-Response Relati

1992
Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Anticholesteremic Agents; Carmustine; Cell Count; Cell Division; Culture Media; Dose-Response Relati

1992
Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Anticholesteremic Agents; Carmustine; Cell Count; Cell Division; Culture Media; Dose-Response Relati

1992
Transport of amino acid amide sarcosinamide and sarcosinamide chloroethylnitrosourea in human glioma SK-MG-1 cells.
    Cancer research, 1990, May-15, Volume: 50, Issue:10

    Topics: Biological Transport, Active; Carmustine; Glioma; Glycine; Humans; Hydrogen-Ion Concentration; In Vi

1990
Transport of amino acid amide sarcosinamide and sarcosinamide chloroethylnitrosourea in human glioma SK-MG-1 cells.
    Cancer research, 1990, May-15, Volume: 50, Issue:10

    Topics: Biological Transport, Active; Carmustine; Glioma; Glycine; Humans; Hydrogen-Ion Concentration; In Vi

1990
Transport of amino acid amide sarcosinamide and sarcosinamide chloroethylnitrosourea in human glioma SK-MG-1 cells.
    Cancer research, 1990, May-15, Volume: 50, Issue:10

    Topics: Biological Transport, Active; Carmustine; Glioma; Glycine; Humans; Hydrogen-Ion Concentration; In Vi

1990
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; C

1991
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; C

1991
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; C

1991
Alkalosis monitored by 31P NMR in a human glioma cell line exposed to the anti-tumor drug 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Magnetic resonance in medicine, 1991, Volume: 22, Issue:2

    Topics: Carmustine; Drug Screening Assays, Antitumor; Glioma; Glucose-6-Phosphate; Glucosephosphates; Humans

1991
Alkalosis monitored by 31P NMR in a human glioma cell line exposed to the anti-tumor drug 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Magnetic resonance in medicine, 1991, Volume: 22, Issue:2

    Topics: Carmustine; Drug Screening Assays, Antitumor; Glioma; Glucose-6-Phosphate; Glucosephosphates; Humans

1991
Alkalosis monitored by 31P NMR in a human glioma cell line exposed to the anti-tumor drug 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Magnetic resonance in medicine, 1991, Volume: 22, Issue:2

    Topics: Carmustine; Drug Screening Assays, Antitumor; Glioma; Glucose-6-Phosphate; Glucosephosphates; Humans

1991
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
    Journal of neuro-oncology, 1991, Volume: 11, Issue:3

    Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therap

1991
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
    Journal of neuro-oncology, 1991, Volume: 11, Issue:3

    Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therap

1991
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
    Journal of neuro-oncology, 1991, Volume: 11, Issue:3

    Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therap

1991
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Combined Modality Therapy; Drug Screening Assays, Antitumor; D

1991
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Combined Modality Therapy; Drug Screening Assays, Antitumor; D

1991
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Combined Modality Therapy; Drug Screening Assays, Antitumor; D

1991
Pharmacokinetics of 11C-labelled BCNU and SarCNU in gliomas studied by PET.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Edetic Acid; Gallium Radio

1991
Pharmacokinetics of 11C-labelled BCNU and SarCNU in gliomas studied by PET.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Edetic Acid; Gallium Radio

1991
Pharmacokinetics of 11C-labelled BCNU and SarCNU in gliomas studied by PET.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Edetic Acid; Gallium Radio

1991
31P magnetic resonance spectroscopy is sensitive to tumor hypoxia: perfusion and oxygenation of rat 9L gliosarcoma after treatment with BCNU.
    NMR in biomedicine, 1991, Volume: 4, Issue:3

    Topics: Animals; Carmustine; Cell Hypoxia; Female; Glioma; Magnetic Resonance Spectroscopy; Oxygen; Perfusio

1991
31P magnetic resonance spectroscopy is sensitive to tumor hypoxia: perfusion and oxygenation of rat 9L gliosarcoma after treatment with BCNU.
    NMR in biomedicine, 1991, Volume: 4, Issue:3

    Topics: Animals; Carmustine; Cell Hypoxia; Female; Glioma; Magnetic Resonance Spectroscopy; Oxygen; Perfusio

1991
31P magnetic resonance spectroscopy is sensitive to tumor hypoxia: perfusion and oxygenation of rat 9L gliosarcoma after treatment with BCNU.
    NMR in biomedicine, 1991, Volume: 4, Issue:3

    Topics: Animals; Carmustine; Cell Hypoxia; Female; Glioma; Magnetic Resonance Spectroscopy; Oxygen; Perfusio

1991
Hyperthermic potentiation of BCNU toxicity in BCNU-resistant human glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:1

    Topics: Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hot Temperatur

1991
Hyperthermic potentiation of BCNU toxicity in BCNU-resistant human glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:1

    Topics: Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hot Temperatur

1991
Hyperthermic potentiation of BCNU toxicity in BCNU-resistant human glioma cells.
    Journal of neuro-oncology, 1991, Volume: 11, Issue:1

    Topics: Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hot Temperatur

1991
A three-dimensional micro-organ culture system optimized for in vitro growth of human malignant brain tumors.
    Neurosurgery, 1991, Volume: 29, Issue:3

    Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Cell Survival; Glioma; Humans; Immunohistoc

1991
A three-dimensional micro-organ culture system optimized for in vitro growth of human malignant brain tumors.
    Neurosurgery, 1991, Volume: 29, Issue:3

    Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Cell Survival; Glioma; Humans; Immunohistoc

1991
A three-dimensional micro-organ culture system optimized for in vitro growth of human malignant brain tumors.
    Neurosurgery, 1991, Volume: 29, Issue:3

    Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Cell Survival; Glioma; Humans; Immunohistoc

1991
Thyroid function after treatment of brain tumors in children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine

1991
Thyroid function after treatment of brain tumors in children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine

1991
Thyroid function after treatment of brain tumors in children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine

1991
In vitro response of human glioblastoma and canine glioma cells to hyperthermia, radiation, and chemotherapy.
    Neurosurgery, 1991, Volume: 29, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cisplatin; Combined Modality Therapy; Dogs; Gli

1991
In vitro response of human glioblastoma and canine glioma cells to hyperthermia, radiation, and chemotherapy.
    Neurosurgery, 1991, Volume: 29, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cisplatin; Combined Modality Therapy; Dogs; Gli

1991
In vitro response of human glioblastoma and canine glioma cells to hyperthermia, radiation, and chemotherapy.
    Neurosurgery, 1991, Volume: 29, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cisplatin; Combined Modality Therapy; Dogs; Gli

1991
Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; DNA; Glioma;

1991
Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; DNA; Glioma;

1991
Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; DNA; Glioma;

1991
Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors.
    Chinese medical journal, 1990, Volume: 103, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine; Brain Neo

1990
Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors.
    Chinese medical journal, 1990, Volume: 103, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine; Brain Neo

1990
Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors.
    Chinese medical journal, 1990, Volume: 103, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine; Brain Neo

1990
Statin expression in the untreated and SarCNU-exposed human glioma cell line, SK-MG-1.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Cycle; Cell Cycle P

1990
Statin expression in the untreated and SarCNU-exposed human glioma cell line, SK-MG-1.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Cycle; Cell Cycle P

1990
Statin expression in the untreated and SarCNU-exposed human glioma cell line, SK-MG-1.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Cycle; Cell Cycle P

1990
The VM model of glioma: preparation of multicellular tumour spheroids (MTS) and their response to chemotherapy.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:2

    Topics: Animals; Carmustine; Cell Division; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma

1990
The VM model of glioma: preparation of multicellular tumour spheroids (MTS) and their response to chemotherapy.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:2

    Topics: Animals; Carmustine; Cell Division; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma

1990
The VM model of glioma: preparation of multicellular tumour spheroids (MTS) and their response to chemotherapy.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:2

    Topics: Animals; Carmustine; Cell Division; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma

1990
[Chemotherapy in malignant gliomas].
    Neurochirurgia, 1990, Volume: 33 Suppl 1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cytarabine; Follow-Up

1990
[Chemotherapy in malignant gliomas].
    Neurochirurgia, 1990, Volume: 33 Suppl 1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cytarabine; Follow-Up

1990
[Chemotherapy in malignant gliomas].
    Neurochirurgia, 1990, Volume: 33 Suppl 1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cytarabine; Follow-Up

1990
Sensitivity of human malignant intracranial tumors against MCNU in vitro in comparison to ACNU and BCNU.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Drug Screening Assays, Antitu

1990
Sensitivity of human malignant intracranial tumors against MCNU in vitro in comparison to ACNU and BCNU.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Drug Screening Assays, Antitu

1990
Sensitivity of human malignant intracranial tumors against MCNU in vitro in comparison to ACNU and BCNU.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Drug Screening Assays, Antitu

1990
Chemosensitivity testing of human gliomas using a fluorescent microcarrier technique.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Benzimidazoles; Carmustine; Cell Division; Drug Screening Assays, Antitumor;

1990
Chemosensitivity testing of human gliomas using a fluorescent microcarrier technique.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Benzimidazoles; Carmustine; Cell Division; Drug Screening Assays, Antitumor;

1990
Chemosensitivity testing of human gliomas using a fluorescent microcarrier technique.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Benzimidazoles; Carmustine; Cell Division; Drug Screening Assays, Antitumor;

1990
Chemotherapy for malignant gliomas of the brain: a review of ten-years experience.
    Acta neurochirurgica, 1990, Volume: 103, Issue:1-2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cyclohexenes; Glioma;

1990
Chemotherapy for malignant gliomas of the brain: a review of ten-years experience.
    Acta neurochirurgica, 1990, Volume: 103, Issue:1-2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cyclohexenes; Glioma;

1990
Chemotherapy for malignant gliomas of the brain: a review of ten-years experience.
    Acta neurochirurgica, 1990, Volume: 103, Issue:1-2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cyclohexenes; Glioma;

1990
Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study.
    Journal of neurosurgery, 1990, Volume: 73, Issue:2

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Drug Screening Assays, Antitumor; Fluorescent D

1990
Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study.
    Journal of neurosurgery, 1990, Volume: 73, Issue:2

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Drug Screening Assays, Antitumor; Fluorescent D

1990
Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study.
    Journal of neurosurgery, 1990, Volume: 73, Issue:2

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Drug Screening Assays, Antitumor; Fluorescent D

1990
Mechanisms of resistance to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) in sensitive and resistant human glioma cells.
    Molecular pharmacology, 1990, Volume: 38, Issue:3

    Topics: Acetyltransferases; Antineoplastic Agents; Biological Transport; Carmustine; DNA; DNA Glycosylases;

1990
Mechanisms of resistance to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) in sensitive and resistant human glioma cells.
    Molecular pharmacology, 1990, Volume: 38, Issue:3

    Topics: Acetyltransferases; Antineoplastic Agents; Biological Transport; Carmustine; DNA; DNA Glycosylases;

1990
Mechanisms of resistance to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) in sensitive and resistant human glioma cells.
    Molecular pharmacology, 1990, Volume: 38, Issue:3

    Topics: Acetyltransferases; Antineoplastic Agents; Biological Transport; Carmustine; DNA; DNA Glycosylases;

1990
[Application of renal subcapsular assay to human malignant glioma--a new screening method in vivo for antitumoral drugs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:7

    Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Carmustine; Cell Division; Cisplatin; Dr

1985
[Application of renal subcapsular assay to human malignant glioma--a new screening method in vivo for antitumoral drugs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:7

    Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Carmustine; Cell Division; Cisplatin; Dr

1985
[Application of renal subcapsular assay to human malignant glioma--a new screening method in vivo for antitumoral drugs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:7

    Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Carmustine; Cell Division; Cisplatin; Dr

1985
Combined intraarterial and systemic chemotherapy for intracerebral tumors.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms;

1987
Combined intraarterial and systemic chemotherapy for intracerebral tumors.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms;

1987
Combined intraarterial and systemic chemotherapy for intracerebral tumors.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms;

1987
An isotope agarose assay for rapid testing of the sensitivity of glioma biopsies to chemotherapeutic drugs and biological response modifiers. Effects of BCNU, vincristine, lymphokines and the recombinant agents interferon alpha 2c, interferon gamma and tu
    Acta neurochirurgica, 1988, Volume: 91, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Biopsy; Carmustine; Cells, Cultured; Child, Prescho

1988
An isotope agarose assay for rapid testing of the sensitivity of glioma biopsies to chemotherapeutic drugs and biological response modifiers. Effects of BCNU, vincristine, lymphokines and the recombinant agents interferon alpha 2c, interferon gamma and tu
    Acta neurochirurgica, 1988, Volume: 91, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Biopsy; Carmustine; Cells, Cultured; Child, Prescho

1988
An isotope agarose assay for rapid testing of the sensitivity of glioma biopsies to chemotherapeutic drugs and biological response modifiers. Effects of BCNU, vincristine, lymphokines and the recombinant agents interferon alpha 2c, interferon gamma and tu
    Acta neurochirurgica, 1988, Volume: 91, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Biopsy; Carmustine; Cells, Cultured; Child, Prescho

1988
The cytotoxicity of a 2-chloroethylnitrosourea analog of sarcosinamide in the SK-MG-1 human glioma cell line as a possible indicator for transport.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Biological Transport; Brain Neoplasms; Carmustine; Cell Line; Dose-Response R

1989
The cytotoxicity of a 2-chloroethylnitrosourea analog of sarcosinamide in the SK-MG-1 human glioma cell line as a possible indicator for transport.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Biological Transport; Brain Neoplasms; Carmustine; Cell Line; Dose-Response R

1989
The cytotoxicity of a 2-chloroethylnitrosourea analog of sarcosinamide in the SK-MG-1 human glioma cell line as a possible indicator for transport.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Biological Transport; Brain Neoplasms; Carmustine; Cell Line; Dose-Response R

1989
Treatment of high grade glioma xenografts with nitrosoureas in nude mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Carmustine; Glioblastoma; Glioma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Nimus

1989
Treatment of high grade glioma xenografts with nitrosoureas in nude mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Carmustine; Glioblastoma; Glioma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Nimus

1989
Treatment of high grade glioma xenografts with nitrosoureas in nude mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Carmustine; Glioblastoma; Glioma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Nimus

1989
Ocular complications after intracarotid BCNU for intracranial tumors.
    Acta ophthalmologica, 1989, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Eye Diseases; Female; Fluorescein Angiography; Gliob

1989
Ocular complications after intracarotid BCNU for intracranial tumors.
    Acta ophthalmologica, 1989, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Eye Diseases; Female; Fluorescein Angiography; Gliob

1989
Ocular complications after intracarotid BCNU for intracranial tumors.
    Acta ophthalmologica, 1989, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Eye Diseases; Female; Fluorescein Angiography; Gliob

1989
Tumour recurrence vs radionecrosis: an indication for multitrajectory serial stereotactic biopsies.
    Acta neurochirurgica. Supplementum, 1989, Volume: 46

    Topics: Astrocytoma; Biopsy, Needle; Brain; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1989
Tumour recurrence vs radionecrosis: an indication for multitrajectory serial stereotactic biopsies.
    Acta neurochirurgica. Supplementum, 1989, Volume: 46

    Topics: Astrocytoma; Biopsy, Needle; Brain; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1989
Tumour recurrence vs radionecrosis: an indication for multitrajectory serial stereotactic biopsies.
    Acta neurochirurgica. Supplementum, 1989, Volume: 46

    Topics: Astrocytoma; Biopsy, Needle; Brain; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1989
[Internal carotid arterial BCNU perfusion in the treatment of cerebral glioma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1989, Volume: 27, Issue:7

    Topics: Adult; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Female; Glioma; Humans; Infusions, Int

1989
[Internal carotid arterial BCNU perfusion in the treatment of cerebral glioma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1989, Volume: 27, Issue:7

    Topics: Adult; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Female; Glioma; Humans; Infusions, Int

1989
[Internal carotid arterial BCNU perfusion in the treatment of cerebral glioma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1989, Volume: 27, Issue:7

    Topics: Adult; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Female; Glioma; Humans; Infusions, Int

1989
Early metabolic changes following chemotherapy of human gliomas in vivo demonstrated by phosphorus magnetic resonance spectroscopy.
    Investigative radiology, 1989, Volume: 24, Issue:12

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Glioma; Humans; Hydrogen-Ion Concentration; Infusions, Int

1989
Early metabolic changes following chemotherapy of human gliomas in vivo demonstrated by phosphorus magnetic resonance spectroscopy.
    Investigative radiology, 1989, Volume: 24, Issue:12

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Glioma; Humans; Hydrogen-Ion Concentration; Infusions, Int

1989
Early metabolic changes following chemotherapy of human gliomas in vivo demonstrated by phosphorus magnetic resonance spectroscopy.
    Investigative radiology, 1989, Volume: 24, Issue:12

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Glioma; Humans; Hydrogen-Ion Concentration; Infusions, Int

1989
Establishment and characterization of human glioblastoma cell lines in vitro and their xenografts in nude mice.
    Onkologie, 1989, Volume: 12, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Karyotyping; Ma

1989
Establishment and characterization of human glioblastoma cell lines in vitro and their xenografts in nude mice.
    Onkologie, 1989, Volume: 12, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Karyotyping; Ma

1989
Establishment and characterization of human glioblastoma cell lines in vitro and their xenografts in nude mice.
    Onkologie, 1989, Volume: 12, Issue:4

    Topics: Animals; Brain Neoplasms; Carmustine; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Karyotyping; Ma

1989
In vivo 31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: dose response of spectral changes.
    Magnetic resonance in medicine, 1989, Volume: 11, Issue:2

    Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Glioma; Magnetic Resonance Spectroscopy; Neop

1989
In vivo 31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: dose response of spectral changes.
    Magnetic resonance in medicine, 1989, Volume: 11, Issue:2

    Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Glioma; Magnetic Resonance Spectroscopy; Neop

1989
In vivo 31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: dose response of spectral changes.
    Magnetic resonance in medicine, 1989, Volume: 11, Issue:2

    Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Glioma; Magnetic Resonance Spectroscopy; Neop

1989
Intravenous BCNU and AZQ in patients with recurrent malignant gliomas.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones;

1989
Intravenous BCNU and AZQ in patients with recurrent malignant gliomas.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones;

1989
Intravenous BCNU and AZQ in patients with recurrent malignant gliomas.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones;

1989
Fatal necrotizing encephalopathy complicating treatment of malignant gliomas with intra-arterial BCNU and irradiation: a pathological study.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:3

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Infusions, I

1989
Fatal necrotizing encephalopathy complicating treatment of malignant gliomas with intra-arterial BCNU and irradiation: a pathological study.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:3

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Infusions, I

1989
Fatal necrotizing encephalopathy complicating treatment of malignant gliomas with intra-arterial BCNU and irradiation: a pathological study.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:3

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Infusions, I

1989
New xenograft model for assessing experimental therapy of central nervous system tumors: human glioblastoma in the intrathecal compartment of the nude mouse.
    Neurosurgery, 1988, Volume: 22, Issue:5

    Topics: Animals; Carmustine; Cell Line; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma; Hu

1988
New xenograft model for assessing experimental therapy of central nervous system tumors: human glioblastoma in the intrathecal compartment of the nude mouse.
    Neurosurgery, 1988, Volume: 22, Issue:5

    Topics: Animals; Carmustine; Cell Line; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma; Hu

1988
New xenograft model for assessing experimental therapy of central nervous system tumors: human glioblastoma in the intrathecal compartment of the nude mouse.
    Neurosurgery, 1988, Volume: 22, Issue:5

    Topics: Animals; Carmustine; Cell Line; Disease Models, Animal; Drug Screening Assays, Antitumor; Glioma; Hu

1988
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatograp

1987
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatograp

1987
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatograp

1987
Application of in vivo and in vitro pharmacokinetics for physiologically relevant drug exposure in a human tumor clonogenic cell assay.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Biological Assay; Brain Neoplasms; Carmustine; Cel

1987
Application of in vivo and in vitro pharmacokinetics for physiologically relevant drug exposure in a human tumor clonogenic cell assay.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Biological Assay; Brain Neoplasms; Carmustine; Cel

1987
Application of in vivo and in vitro pharmacokinetics for physiologically relevant drug exposure in a human tumor clonogenic cell assay.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Biological Assay; Brain Neoplasms; Carmustine; Cel

1987
Ischemic optic neuropathy secondary to intracarotid infusion of BCNU.
    Journal of clinical neuro-ophthalmology, 1987, Volume: 7, Issue:2

    Topics: Adult; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Fluorescein Angiography; Glioma; Human

1987
Ischemic optic neuropathy secondary to intracarotid infusion of BCNU.
    Journal of clinical neuro-ophthalmology, 1987, Volume: 7, Issue:2

    Topics: Adult; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Fluorescein Angiography; Glioma; Human

1987
Ischemic optic neuropathy secondary to intracarotid infusion of BCNU.
    Journal of clinical neuro-ophthalmology, 1987, Volume: 7, Issue:2

    Topics: Adult; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Fluorescein Angiography; Glioma; Human

1987
Superselective cerebral arterial infusion of BCNU in high-grade glioma: the radiologist's point of view.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1988, Volume: 39, Issue:3

    Topics: Brain Neoplasms; Carmustine; Catheterization; Cerebral Angiography; Cerebral Arteries; Female; Gliom

1988
Superselective cerebral arterial infusion of BCNU in high-grade glioma: the radiologist's point of view.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1988, Volume: 39, Issue:3

    Topics: Brain Neoplasms; Carmustine; Catheterization; Cerebral Angiography; Cerebral Arteries; Female; Gliom

1988
Superselective cerebral arterial infusion of BCNU in high-grade glioma: the radiologist's point of view.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1988, Volume: 39, Issue:3

    Topics: Brain Neoplasms; Carmustine; Catheterization; Cerebral Angiography; Cerebral Arteries; Female; Gliom

1988
Ocular and orbital toxicity following intracarotid injection of BCNU (carmustine) and cisplatinum for malignant gliomas.
    Ophthalmology, 1985, Volume: 92, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Carotid Arteries

1985
Ocular and orbital toxicity following intracarotid injection of BCNU (carmustine) and cisplatinum for malignant gliomas.
    Ophthalmology, 1985, Volume: 92, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Carotid Arteries

1985
Ocular and orbital toxicity following intracarotid injection of BCNU (carmustine) and cisplatinum for malignant gliomas.
    Ophthalmology, 1985, Volume: 92, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Carotid Arteries

1985
Radiotherapy and combination chemotherapy with carmustine, vincristine, and procarbazine (BVP) in primary brain tumors.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Combined M

1985
Radiotherapy and combination chemotherapy with carmustine, vincristine, and procarbazine (BVP) in primary brain tumors.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Combined M

1985
Radiotherapy and combination chemotherapy with carmustine, vincristine, and procarbazine (BVP) in primary brain tumors.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Combined M

1985
Supraophthalmic carotid infusion for recurrent glioma: rationale, technique, and preliminary results for cisplatin and BCNU.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Car

1985
Supraophthalmic carotid infusion for recurrent glioma: rationale, technique, and preliminary results for cisplatin and BCNU.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Car

1985
Supraophthalmic carotid infusion for recurrent glioma: rationale, technique, and preliminary results for cisplatin and BCNU.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Car

1985
Intensive 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) monochemotherapy and autologous marrow transplantation for malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Aged; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Chil

1986
Intensive 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) monochemotherapy and autologous marrow transplantation for malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Aged; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Chil

1986
Intensive 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) monochemotherapy and autologous marrow transplantation for malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Aged; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Chil

1986
Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas.
    Cancer treatment reports, 1986, Volume: 70, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1986
Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas.
    Cancer treatment reports, 1986, Volume: 70, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1986
Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas.
    Cancer treatment reports, 1986, Volume: 70, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

1986
Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.
    Acta neurochirurgica, 1987, Volume: 85, Issue:3-4

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy; Follow-Up Stu

1987
Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.
    Acta neurochirurgica, 1987, Volume: 85, Issue:3-4

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy; Follow-Up Stu

1987
Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.
    Acta neurochirurgica, 1987, Volume: 85, Issue:3-4

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy; Follow-Up Stu

1987
Effect of difluoromethylornithine on the antiglioma therapeutic efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1986, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Eflornithine;

1986
Effect of difluoromethylornithine on the antiglioma therapeutic efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1986, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Eflornithine;

1986
Effect of difluoromethylornithine on the antiglioma therapeutic efficacy of intra-arterial BCNU.
    Journal of neurosurgery, 1986, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Eflornithine;

1986
Sensitivity of human glioma cells to cytotoxic heteroconjugates.
    International journal of cancer, 1988, Sep-15, Volume: 42, Issue:3

    Topics: Animals; Antigens, Neoplasm; Carmustine; Cell Survival; Glioma; HLA-DR Antigens; Humans; Immunotoxin

1988
Sensitivity of human glioma cells to cytotoxic heteroconjugates.
    International journal of cancer, 1988, Sep-15, Volume: 42, Issue:3

    Topics: Animals; Antigens, Neoplasm; Carmustine; Cell Survival; Glioma; HLA-DR Antigens; Humans; Immunotoxin

1988
Sensitivity of human glioma cells to cytotoxic heteroconjugates.
    International journal of cancer, 1988, Sep-15, Volume: 42, Issue:3

    Topics: Animals; Antigens, Neoplasm; Carmustine; Cell Survival; Glioma; HLA-DR Antigens; Humans; Immunotoxin

1988
Effect of Fluosol-DA on the response of intracranial 9L tumors to X rays and BCNU.
    International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:5

    Topics: Administration, Inhalation; Animals; Brain Neoplasms; Carbon Dioxide; Carmustine; Combined Modality

1988
Effect of Fluosol-DA on the response of intracranial 9L tumors to X rays and BCNU.
    International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:5

    Topics: Administration, Inhalation; Animals; Brain Neoplasms; Carbon Dioxide; Carmustine; Combined Modality

1988
Effect of Fluosol-DA on the response of intracranial 9L tumors to X rays and BCNU.
    International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:5

    Topics: Administration, Inhalation; Animals; Brain Neoplasms; Carbon Dioxide; Carmustine; Combined Modality

1988
[Mechanisms of cellular resistance to chloroethylnitrosourea in cell lines derived from human brain tumors].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:3

    Topics: Brain Neoplasms; Carmustine; Cell Line; DNA Damage; Drug Resistance; Glioma; Humans; Nimustine; Nitr

1988
[Mechanisms of cellular resistance to chloroethylnitrosourea in cell lines derived from human brain tumors].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:3

    Topics: Brain Neoplasms; Carmustine; Cell Line; DNA Damage; Drug Resistance; Glioma; Humans; Nimustine; Nitr

1988
[Mechanisms of cellular resistance to chloroethylnitrosourea in cell lines derived from human brain tumors].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:3

    Topics: Brain Neoplasms; Carmustine; Cell Line; DNA Damage; Drug Resistance; Glioma; Humans; Nimustine; Nitr

1988
Establishment, characterization and chemosensitivity of two human glioma derived cell lines.
    Journal of neuro-oncology, 1988, Volume: 6, Issue:2

    Topics: Animals; Carmustine; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cisplatin; Culture Techniq

1988
Establishment, characterization and chemosensitivity of two human glioma derived cell lines.
    Journal of neuro-oncology, 1988, Volume: 6, Issue:2

    Topics: Animals; Carmustine; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cisplatin; Culture Techniq

1988
Establishment, characterization and chemosensitivity of two human glioma derived cell lines.
    Journal of neuro-oncology, 1988, Volume: 6, Issue:2

    Topics: Animals; Carmustine; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cisplatin; Culture Techniq

1988
Comparison of in vitro cloning assays for drug sensitivity testing of human brain tumours.
    British journal of neurosurgery, 1988, Volume: 2, Issue:2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Colony-Forming Units

1988
Comparison of in vitro cloning assays for drug sensitivity testing of human brain tumours.
    British journal of neurosurgery, 1988, Volume: 2, Issue:2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Colony-Forming Units

1988
Comparison of in vitro cloning assays for drug sensitivity testing of human brain tumours.
    British journal of neurosurgery, 1988, Volume: 2, Issue:2

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Colony-Forming Units

1988
More on the question of chemotherapy for CNS glioma.
    Oncology (Williston Park, N.Y.), 1987, Volume: 1, Issue:10

    Topics: Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans

1987
More on the question of chemotherapy for CNS glioma.
    Oncology (Williston Park, N.Y.), 1987, Volume: 1, Issue:10

    Topics: Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans

1987
More on the question of chemotherapy for CNS glioma.
    Oncology (Williston Park, N.Y.), 1987, Volume: 1, Issue:10

    Topics: Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans

1987
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
    Cancer research, 1988, Feb-01, Volume: 48, Issue:3

    Topics: Animals; Carmustine; Energy Metabolism; Extracellular Space; Glioma; Magnetic Resonance Spectroscopy

1988
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
    Cancer research, 1988, Feb-01, Volume: 48, Issue:3

    Topics: Animals; Carmustine; Energy Metabolism; Extracellular Space; Glioma; Magnetic Resonance Spectroscopy

1988
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
    Cancer research, 1988, Feb-01, Volume: 48, Issue:3

    Topics: Animals; Carmustine; Energy Metabolism; Extracellular Space; Glioma; Magnetic Resonance Spectroscopy

1988
Selective delivery of chemotherapeutic agents with a new catheter system.
    Radiology, 1988, Volume: 166, Issue:2

    Topics: Brain Neoplasms; Carmustine; Carotid Artery, Internal; Catheters, Indwelling; Cerebral Arteries; Gli

1988
Selective delivery of chemotherapeutic agents with a new catheter system.
    Radiology, 1988, Volume: 166, Issue:2

    Topics: Brain Neoplasms; Carmustine; Carotid Artery, Internal; Catheters, Indwelling; Cerebral Arteries; Gli

1988
Selective delivery of chemotherapeutic agents with a new catheter system.
    Radiology, 1988, Volume: 166, Issue:2

    Topics: Brain Neoplasms; Carmustine; Carotid Artery, Internal; Catheters, Indwelling; Cerebral Arteries; Gli

1988
Visual system toxicity following intra-arterial chemotherapy.
    Neurology, 1988, Volume: 38, Issue:2

    Topics: Brain Neoplasms; Carmustine; Cisplatin; Glioma; Humans; Infusions, Intra-Arterial; Retinal Diseases;

1988
Visual system toxicity following intra-arterial chemotherapy.
    Neurology, 1988, Volume: 38, Issue:2

    Topics: Brain Neoplasms; Carmustine; Cisplatin; Glioma; Humans; Infusions, Intra-Arterial; Retinal Diseases;

1988
Visual system toxicity following intra-arterial chemotherapy.
    Neurology, 1988, Volume: 38, Issue:2

    Topics: Brain Neoplasms; Carmustine; Cisplatin; Glioma; Humans; Infusions, Intra-Arterial; Retinal Diseases;

1988
Patterns of recurrence in glioma patients after interstitial irradiation and chemotherapy: report of three cases.
    Neurosurgery, 1988, Volume: 22, Issue:3

    Topics: Adult; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans

1988
Patterns of recurrence in glioma patients after interstitial irradiation and chemotherapy: report of three cases.
    Neurosurgery, 1988, Volume: 22, Issue:3

    Topics: Adult; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans

1988
Patterns of recurrence in glioma patients after interstitial irradiation and chemotherapy: report of three cases.
    Neurosurgery, 1988, Volume: 22, Issue:3

    Topics: Adult; Brachytherapy; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans

1988
Pilot studies of microwave-induced brain hyperthermia and systemic BCNU in a rat glioblastoma model.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 107

    Topics: Animals; Carmustine; Combined Modality Therapy; Female; Glioma; Hyperthermia, Induced; Male; Microwa

1988
Pilot studies of microwave-induced brain hyperthermia and systemic BCNU in a rat glioblastoma model.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 107

    Topics: Animals; Carmustine; Combined Modality Therapy; Female; Glioma; Hyperthermia, Induced; Male; Microwa

1988
Pilot studies of microwave-induced brain hyperthermia and systemic BCNU in a rat glioblastoma model.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 107

    Topics: Animals; Carmustine; Combined Modality Therapy; Female; Glioma; Hyperthermia, Induced; Male; Microwa

1988
The cytotoxicity of sarcosinamide chloroethylnitrosourea (SarCNU) and BCNU in primary gliomas and glioma cell lines: analysis of data in reference to theoretical peak plasma concentrations in man.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:2

    Topics: Carmustine; Cell Line; Cell Survival; Glioma; Humans; Lethal Dose 50; Tumor Stem Cell Assay

1988
The cytotoxicity of sarcosinamide chloroethylnitrosourea (SarCNU) and BCNU in primary gliomas and glioma cell lines: analysis of data in reference to theoretical peak plasma concentrations in man.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:2

    Topics: Carmustine; Cell Line; Cell Survival; Glioma; Humans; Lethal Dose 50; Tumor Stem Cell Assay

1988
The cytotoxicity of sarcosinamide chloroethylnitrosourea (SarCNU) and BCNU in primary gliomas and glioma cell lines: analysis of data in reference to theoretical peak plasma concentrations in man.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:2

    Topics: Carmustine; Cell Line; Cell Survival; Glioma; Humans; Lethal Dose 50; Tumor Stem Cell Assay

1988
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
    Cancer research, 1988, Oct-01, Volume: 48, Issue:19

    Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Humans; Magnetic Resonance Spectroscopy; Necrosis; Rat

1988
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
    Cancer research, 1988, Oct-01, Volume: 48, Issue:19

    Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Humans; Magnetic Resonance Spectroscopy; Necrosis; Rat

1988
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
    Cancer research, 1988, Oct-01, Volume: 48, Issue:19

    Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Humans; Magnetic Resonance Spectroscopy; Necrosis; Rat

1988
31P and 1H NMR spectroscopy of tumors in vivo: untreated growth and response to chemotherapy.
    Annals of the New York Academy of Sciences, 1987, Volume: 508

    Topics: Animals; Carmustine; Cyclophosphamide; Fibrosarcoma; Glioma; Hydrogen; Magnetic Resonance Spectrosco

1987
31P and 1H NMR spectroscopy of tumors in vivo: untreated growth and response to chemotherapy.
    Annals of the New York Academy of Sciences, 1987, Volume: 508

    Topics: Animals; Carmustine; Cyclophosphamide; Fibrosarcoma; Glioma; Hydrogen; Magnetic Resonance Spectrosco

1987
31P and 1H NMR spectroscopy of tumors in vivo: untreated growth and response to chemotherapy.
    Annals of the New York Academy of Sciences, 1987, Volume: 508

    Topics: Animals; Carmustine; Cyclophosphamide; Fibrosarcoma; Glioma; Hydrogen; Magnetic Resonance Spectrosco

1987
Cellular resistance to chloroethylnitrosoureas, nitrogen mustard, and cis-diamminedichloroplatinum(II) in human glial-derived cell lines.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resista

1987
Cellular resistance to chloroethylnitrosoureas, nitrogen mustard, and cis-diamminedichloroplatinum(II) in human glial-derived cell lines.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resista

1987
Cellular resistance to chloroethylnitrosoureas, nitrogen mustard, and cis-diamminedichloroplatinum(II) in human glial-derived cell lines.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resista

1987
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Hum

1987
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Hum

1987
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Hum

1987
Pharmacokinetics of superselective intra-arterial and intravenous [11C]BCNU evaluated by PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1986, Volume: 27, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Drug Evaluation; Female; Glioma; Hal

1986
Pharmacokinetics of superselective intra-arterial and intravenous [11C]BCNU evaluated by PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1986, Volume: 27, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Drug Evaluation; Female; Glioma; Hal

1986
Pharmacokinetics of superselective intra-arterial and intravenous [11C]BCNU evaluated by PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1986, Volume: 27, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Drug Evaluation; Female; Glioma; Hal

1986
Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:5

    Topics: Adult; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1987
Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:5

    Topics: Adult; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1987
Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:5

    Topics: Adult; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female;

1987
Intracarotid chemotherapy with 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in 5% dextrose in water in the treatment of malignant glioma.
    Neurosurgery, 1987, Volume: 20, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy;

1987
Intracarotid chemotherapy with 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in 5% dextrose in water in the treatment of malignant glioma.
    Neurosurgery, 1987, Volume: 20, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy;

1987
Intracarotid chemotherapy with 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in 5% dextrose in water in the treatment of malignant glioma.
    Neurosurgery, 1987, Volume: 20, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy;

1987
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy

1987
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy

1987
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy

1987
Intracranial BCNU.
    Neurosurgery, 1987, Volume: 21, Issue:1

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Infusions, Intra-Arterial

1987
Intracranial BCNU.
    Neurosurgery, 1987, Volume: 21, Issue:1

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Infusions, Intra-Arterial

1987
Intracranial BCNU.
    Neurosurgery, 1987, Volume: 21, Issue:1

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Infusions, Intra-Arterial

1987
Inhibition of O6-alkylguanine-DNA-alkyltransferase activity potentiates cytotoxicity and induction of SCEs in human glioma cells resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Carmustine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hum

1987
Inhibition of O6-alkylguanine-DNA-alkyltransferase activity potentiates cytotoxicity and induction of SCEs in human glioma cells resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Carmustine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hum

1987
Inhibition of O6-alkylguanine-DNA-alkyltransferase activity potentiates cytotoxicity and induction of SCEs in human glioma cells resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Carmustine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Hum

1987
Intracarotid BCNU for glioma.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Female; Glioma; Humans; Injections, Intr

1987
Intracarotid BCNU for glioma.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Female; Glioma; Humans; Injections, Intr

1987
Intracarotid BCNU for glioma.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Female; Glioma; Humans; Injections, Intr

1987
Hyperprolactinemia and hypothyroidism following cytotoxic therapy for central nervous system malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Child; Child, Preschool;

1987
Hyperprolactinemia and hypothyroidism following cytotoxic therapy for central nervous system malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Child; Child, Preschool;

1987
Hyperprolactinemia and hypothyroidism following cytotoxic therapy for central nervous system malignancies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Child; Child, Preschool;

1987
Drug cytotoxicity at elevated temperature. In vitro study on the U-87MG glioma cell line.
    Journal of neurosurgery, 1987, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Cisplatin;

1987
Drug cytotoxicity at elevated temperature. In vitro study on the U-87MG glioma cell line.
    Journal of neurosurgery, 1987, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Cisplatin;

1987
Drug cytotoxicity at elevated temperature. In vitro study on the U-87MG glioma cell line.
    Journal of neurosurgery, 1987, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Cisplatin;

1987
Superselective intracerebral chemotherapy of malignant tumours with BCNU. Neuroradiological considerations.
    Neuroradiology, 1986, Volume: 28, Issue:2

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Catheterization;

1986
Superselective intracerebral chemotherapy of malignant tumours with BCNU. Neuroradiological considerations.
    Neuroradiology, 1986, Volume: 28, Issue:2

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Catheterization;

1986
Superselective intracerebral chemotherapy of malignant tumours with BCNU. Neuroradiological considerations.
    Neuroradiology, 1986, Volume: 28, Issue:2

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Catheterization;

1986
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1986, Volume: 7, Issue:6

    Topics: Alkylation; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Dose-Response Relationship, Drug;

1986
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1986, Volume: 7, Issue:6

    Topics: Alkylation; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Dose-Response Relationship, Drug;

1986
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1986, Volume: 7, Issue:6

    Topics: Alkylation; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Dose-Response Relationship, Drug;

1986
Supraophthalmic intracarotid infusion of BCNU for malignant glioma.
    Neurology, 1986, Volume: 36, Issue:11

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Infusions, Intravenous; Male; Middle Age

1986
Supraophthalmic intracarotid infusion of BCNU for malignant glioma.
    Neurology, 1986, Volume: 36, Issue:11

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Infusions, Intravenous; Male; Middle Age

1986
Supraophthalmic intracarotid infusion of BCNU for malignant glioma.
    Neurology, 1986, Volume: 36, Issue:11

    Topics: Adult; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Infusions, Intravenous; Male; Middle Age

1986
Experiences with sodium thiosulfate after intracarotid infusion of cisplatin and BCNU for malignant gliomas.
    Journal of neuro-oncology, 1986, Volume: 4, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1986
Experiences with sodium thiosulfate after intracarotid infusion of cisplatin and BCNU for malignant gliomas.
    Journal of neuro-oncology, 1986, Volume: 4, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1986
Experiences with sodium thiosulfate after intracarotid infusion of cisplatin and BCNU for malignant gliomas.
    Journal of neuro-oncology, 1986, Volume: 4, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin;

1986
Neurological deficit after carotid infusion of cisplatin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for malignant glioma: an analysis of risk factors.
    Neurosurgery, 1986, Volume: 19, Issue:5

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Cisplatin; Glioma; Humans; In

1986
Neurological deficit after carotid infusion of cisplatin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for malignant glioma: an analysis of risk factors.
    Neurosurgery, 1986, Volume: 19, Issue:5

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Cisplatin; Glioma; Humans; In

1986
Neurological deficit after carotid infusion of cisplatin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for malignant glioma: an analysis of risk factors.
    Neurosurgery, 1986, Volume: 19, Issue:5

    Topics: Brain Diseases; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Cisplatin; Glioma; Humans; In

1986
Prediction of human tumor cell chemosensitivity using the sister chromatid exchange assay.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Colony-Forming Units Assay; Dose-Response Rel

1986
Prediction of human tumor cell chemosensitivity using the sister chromatid exchange assay.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Colony-Forming Units Assay; Dose-Response Rel

1986
Prediction of human tumor cell chemosensitivity using the sister chromatid exchange assay.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Colony-Forming Units Assay; Dose-Response Rel

1986
Supraophthalmic carotid infusion with low dose cisplatin and BCNU for malignant glioma.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Carmustine; Carotid Arteries; Cisplatin; Dose-Response Relationship, Drug; Glioma;

1986
Supraophthalmic carotid infusion with low dose cisplatin and BCNU for malignant glioma.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Carmustine; Carotid Arteries; Cisplatin; Dose-Response Relationship, Drug; Glioma;

1986
Supraophthalmic carotid infusion with low dose cisplatin and BCNU for malignant glioma.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Carmustine; Carotid Arteries; Cisplatin; Dose-Response Relationship, Drug; Glioma;

1986
Central neurotoxicity following intracarotid BCNU chemotherapy for malignant gliomas.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Carmustine; Glioma; Hemiplegia; Humans; Injections, Intra-Arterial; Time Factors; T

1986
Central neurotoxicity following intracarotid BCNU chemotherapy for malignant gliomas.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Carmustine; Glioma; Hemiplegia; Humans; Injections, Intra-Arterial; Time Factors; T

1986
Central neurotoxicity following intracarotid BCNU chemotherapy for malignant gliomas.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Brain Neoplasms; Carmustine; Glioma; Hemiplegia; Humans; Injections, Intra-Arterial; Time Factors; T

1986
Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Diazepam; Droperidol; Drug Therapy, Comb

1986
Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Diazepam; Droperidol; Drug Therapy, Comb

1986
Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Diazepam; Droperidol; Drug Therapy, Comb

1986
Utilization of the HTSCA and CFU-C assay to identify two new 2-chloroethylnitrosourea congeners of amino acid amides with increased in vitro activity against human glioma compared with BCNU.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Colony-Forming Units Assay; Glioma; Humans; In Vitro

1985
Utilization of the HTSCA and CFU-C assay to identify two new 2-chloroethylnitrosourea congeners of amino acid amides with increased in vitro activity against human glioma compared with BCNU.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Colony-Forming Units Assay; Glioma; Humans; In Vitro

1985
Utilization of the HTSCA and CFU-C assay to identify two new 2-chloroethylnitrosourea congeners of amino acid amides with increased in vitro activity against human glioma compared with BCNU.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Colony-Forming Units Assay; Glioma; Humans; In Vitro

1985
Intra-arterial BCNU chemotherapy for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 62, Issue:3

    Topics: Brain Neoplasms; Carmustine; Diffuse Cerebral Sclerosis of Schilder; Glioma; Humans; Injections, Int

1985
Intra-arterial BCNU chemotherapy for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 62, Issue:3

    Topics: Brain Neoplasms; Carmustine; Diffuse Cerebral Sclerosis of Schilder; Glioma; Humans; Injections, Int

1985
Intra-arterial BCNU chemotherapy for malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 62, Issue:3

    Topics: Brain Neoplasms; Carmustine; Diffuse Cerebral Sclerosis of Schilder; Glioma; Humans; Injections, Int

1985
Thymidine kinase in brain-tumor cysts.
    Journal of neurosurgery, 1985, Volume: 63, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cysts; Glioma; Humans; Thymidine Kinase

1985
Thymidine kinase in brain-tumor cysts.
    Journal of neurosurgery, 1985, Volume: 63, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cysts; Glioma; Humans; Thymidine Kinase

1985
Thymidine kinase in brain-tumor cysts.
    Journal of neurosurgery, 1985, Volume: 63, Issue:4

    Topics: Brain Neoplasms; Carmustine; Cysts; Glioma; Humans; Thymidine Kinase

1985
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy for the treatment of malignant gliomas of the brain: a preliminary report.
    Surgical neurology, 1985, Volume: 24, Issue:5

    Topics: Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intra-Arterial; Male; Middle

1985
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy for the treatment of malignant gliomas of the brain: a preliminary report.
    Surgical neurology, 1985, Volume: 24, Issue:5

    Topics: Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intra-Arterial; Male; Middle

1985
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy for the treatment of malignant gliomas of the brain: a preliminary report.
    Surgical neurology, 1985, Volume: 24, Issue:5

    Topics: Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intra-Arterial; Male; Middle

1985
Intra-arterial and intravenous chemotherapy for the treatment of malignant glioma. Preliminary results.
    American journal of clinical oncology, 1985, Volume: 8, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; C

1985
Intra-arterial and intravenous chemotherapy for the treatment of malignant glioma. Preliminary results.
    American journal of clinical oncology, 1985, Volume: 8, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; C

1985
Intra-arterial and intravenous chemotherapy for the treatment of malignant glioma. Preliminary results.
    American journal of clinical oncology, 1985, Volume: 8, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; C

1985
Reduced systemic drug exposure by combining intra-arterial chemotherapy with hemoperfusion of regional venous drainage.
    Journal of neurosurgery, 1985, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Extracorporeal Circulation; Female; Glioma; Hemoperf

1985
Reduced systemic drug exposure by combining intra-arterial chemotherapy with hemoperfusion of regional venous drainage.
    Journal of neurosurgery, 1985, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Extracorporeal Circulation; Female; Glioma; Hemoperf

1985
Reduced systemic drug exposure by combining intra-arterial chemotherapy with hemoperfusion of regional venous drainage.
    Journal of neurosurgery, 1985, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Extracorporeal Circulation; Female; Glioma; Hemoperf

1985
Rationale for preirradiation chemotherapy in treatment of malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:6

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Premedication

1985
Rationale for preirradiation chemotherapy in treatment of malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:6

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Premedication

1985
Rationale for preirradiation chemotherapy in treatment of malignant gliomas.
    Journal of neurosurgery, 1985, Volume: 63, Issue:6

    Topics: Brain Neoplasms; Carmustine; Glioma; Humans; Premedication

1985
Topographic electroencephalographic study with power ratio index mapping in patients with malignant brain tumors.
    Neurosurgery, 1985, Volume: 17, Issue:4

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Carmustine; Cerebral Cortex; Electroencephalography; Fema

1985
Topographic electroencephalographic study with power ratio index mapping in patients with malignant brain tumors.
    Neurosurgery, 1985, Volume: 17, Issue:4

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Carmustine; Cerebral Cortex; Electroencephalography; Fema

1985
Topographic electroencephalographic study with power ratio index mapping in patients with malignant brain tumors.
    Neurosurgery, 1985, Volume: 17, Issue:4

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Carmustine; Cerebral Cortex; Electroencephalography; Fema

1985
[Clonogenicity and BCNU response of subpopulations of human glioma cells sorted according to DNA content].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:7

    Topics: Adult; Carmustine; Cell Separation; Cells, Cultured; Child; Colony-Forming Units Assay; DNA, Neoplas

1985
[Clonogenicity and BCNU response of subpopulations of human glioma cells sorted according to DNA content].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:7

    Topics: Adult; Carmustine; Cell Separation; Cells, Cultured; Child; Colony-Forming Units Assay; DNA, Neoplas

1985
[Clonogenicity and BCNU response of subpopulations of human glioma cells sorted according to DNA content].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:7

    Topics: Adult; Carmustine; Cell Separation; Cells, Cultured; Child; Colony-Forming Units Assay; DNA, Neoplas

1985
Necrotizing encephalopathy following intraventricular instillation of methotrexate.
    Archives of neurology, 1973, Volume: 28, Issue:2

    Topics: Adolescent; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Cerebral Ventr

1973
Necrotizing encephalopathy following intraventricular instillation of methotrexate.
    Archives of neurology, 1973, Volume: 28, Issue:2

    Topics: Adolescent; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Cerebral Ventr

1973
Necrotizing encephalopathy following intraventricular instillation of methotrexate.
    Archives of neurology, 1973, Volume: 28, Issue:2

    Topics: Adolescent; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Cerebral Ventr

1973
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso

1972
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso

1972
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso

1972