carmustine has been researched along with Eye Disorders in 7 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-nine patients with malignant gliomas (19 anaplastic astrocytomas and 60 glioblastoma multiforme) received 4 cycles of infra-ophthalmic carotid injection of 160 mg carmustine, 2 mg vincristine IV and procarbazine orally 50 mg 3 times daily for 1 week, followed by whole-brain irradiation, with a midpoint dose of 54 Gy/6 weeks." | 5.07 | Combined intra-arterial chemotherapy and irradiation of malignant gliomas. ( Hager, B; Hirschberg, H; Nome, O; Watne, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shingleton, BJ | 1 |
| Bienfang, DC | 1 |
| Albert, DM | 1 |
| Ensminger, WD | 1 |
| Chandler, WF | 1 |
| Greenberg, HS | 1 |
| Arroyo, MH | 1 |
| Refojo, MF | 2 |
| Araiz, JJ | 1 |
| Tolentino, FI | 2 |
| Cajita, VN | 2 |
| Elner, VM | 1 |
| Watne, K | 2 |
| Nome, O | 1 |
| Hager, B | 2 |
| Hirschberg, H | 1 |
| Rogers, LR | 2 |
| Purvis, JB | 1 |
| Lederman, RJ | 2 |
| Rosenbloom, SA | 1 |
| Tomsak, RL | 2 |
| Estes, ML | 1 |
| Magdinec, M | 1 |
| Medendorp, SV | 1 |
| Boyett, JM | 1 |
| Elsås, T | 1 |
| Fostad, K | 1 |
| Miller, DF | 1 |
| Bay, JW | 1 |
| Purvis, JD | 1 |
| Chung, H | 1 |
| Ueno, N | 1 |
2 trials available for carmustine and Eye Disorders
| Article | Year |
|---|---|
Combined intra-arterial chemotherapy and irradiation of malignant gliomas.
Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Carmustine; Combined Modality Therapy; Eye Diseases | 1991 |
Alternating sequential intracarotid BCNU and cisplatin in recurrent malignant glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modalit | 1991 |
5 other studies available for carmustine and Eye Disorders
| Article | Year |
|---|---|
Ocular toxicity associated with high-dose carmustine.
Topics: Adult; Carmustine; Choroid; Eye Diseases; Female; Fluorescein Angiography; Humans; Infusions, Intra- | 1982 |
Silicone oil as a delivery vehicle for BCNU in rabbit proliferative vitreoretinopathy.
Topics: Animals; Carmustine; Cells, Cultured; Conjunctiva; Disease Models, Animal; Drug Carriers; Drug Deliv | 1993 |
Ocular complications after intracarotid BCNU for intracranial tumors.
Topics: Adolescent; Adult; Brain Neoplasms; Carmustine; Eye Diseases; Female; Fluorescein Angiography; Gliob | 1989 |
Ocular and orbital toxicity following intracarotid injection of BCNU (carmustine) and cisplatinum for malignant gliomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Carotid Arteries | 1985 |
BCNU in silicone oil in proliferative vitreoretinopathy: I. Solubility, stability (in vitro and in vivo), and antiproliferative (in vitro) studies.
Topics: Animals; Aqueous Humor; Carmustine; Cattle; Cell Division; Cells, Cultured; Drug Stability; Eye Dise | 1988 |