carmustine has been researched along with Experimental Neoplasms in 190 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levamisole was evaluated as an immune stimulant in a randomized controlled study of patients with anaplastic gliomas, who had undergone surgical resection and who were also treated with radiotherapy and BCNU chemotherapy." | 9.05 | Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model. ( Aronin, P; Dudka, L; Mahaley, MS; Steinbok, P; Zinn, D, 1981) |
| "Using the avian sarcoma virus (ASV) rat glioma model, we have evaluated the in vivo effectiveness of two lipid-soluble folate antagonists, metoprine (DDMP) and its 6-ethyl analog etoprine." | 7.66 | Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. ( Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW, 1982) |
| "We investigated the effects of combinations of BCNU and misonidazole, and melphalan and misonidazole on growth delay in two human malignant melanoma xenograft lines grown in immune-deprived mice." | 7.66 | Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts. ( Clutterbuck, RD; McElwain, TJ; Millar, JL, 1982) |
| "Levamisole was evaluated as an immune stimulant in a randomized controlled study of patients with anaplastic gliomas, who had undergone surgical resection and who were also treated with radiotherapy and BCNU chemotherapy." | 5.05 | Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model. ( Aronin, P; Dudka, L; Mahaley, MS; Steinbok, P; Zinn, D, 1981) |
| "The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas." | 3.76 | Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells. ( Hirose, Y; Kawase, T; Ohba, S; Yazaki, T; Yoshida, K, 2010) |
| " BCNU, fotemustin, and temozolomide dramatically increased the time of survival of the Hs683 oligodendroglioma-bearing mice, whereas temozolomide only induced a weak but nevertheless statistically significant increase in the U373 glioma-bearing mice." | 3.71 | Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy. ( Branle, F; Camby, I; Geurts-Moespot, A; Jeuken, J; Kiss, R; Lefranc, F; Salmon, I; Sprenger, S; Sweep, F, 2002) |
| "Poorly-differentiated human brain glioma xenografted nude mice were treated with carmustine(1, 3-bis-(2-chloroethyl)-1-nitrosourea, BCNU) and sodium phenylbutyrate (SPB)." | 3.71 | [Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug]. ( Dong, J; Huang, Q; Lan, Q; Shi, MG; Sun, ZF, 2002) |
| "A preliminary analysis of our double high-dose chemotherapy with stem cell rescue (HD-SCR) clinical trial for breast cancer, and preclinical cross-resistant studies, suggested that melphalan (M) adversely affected response to subsequent chemotherapy, i." | 3.70 | Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence. ( Ara, G; Bunnell, C; Elias, A; Frei, E; Richardson, P; Teicher, B; Tew, K; Wheeler, C, 2000) |
| "High-dose chemotherapy with a 3-day regimen of cyclophosphamide, cisplatin, and carmustine was used to treat mice bearing experimental lung metastases of mammary tumor cell lines with selectable markers (lines 66cl4 and 4TO7)." | 3.70 | Use of tumor lines with selectable markers in assessing the effect on experimental metastases of combination chemotherapy with alkylating agents. ( Delmonico, L; Miller, BE; Miller, FR; Vistisen, K, 1998) |
| "Using the avian sarcoma virus (ASV) rat glioma model, we have evaluated the in vivo effectiveness of two lipid-soluble folate antagonists, metoprine (DDMP) and its 6-ethyl analog etoprine." | 3.66 | Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. ( Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW, 1982) |
| "Sustained release of carmustine (1,3-bis[2-chloroethyl]-1-nitrosourea, or BCNU) via an episcleral implanted silicone device was used to treat Greene hamster melanoma implanted in the anterior chamber of rabbit eyes." | 3.66 | Sustained release of carmustine (BCNU) for treatment of experimental intraocular malignancy. ( Albert, DM; Liu, LH; Ni, C; Refojo, MF; Ueno, N, 1983) |
| "A human medulloblastoma (BN-2) and a glioblastoma (BN-3) which were previously established in nude mice were used to determine the effect of combined modality therapy with gamma-radiation, and three chemotherapeutic agents, procarbazine, 1,4-cyclohexadiene-1,4-dicarbamic acid, 2,5-bis(1-aziridinyl)-3,6-dioxo diethylester (AZQ), and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)." | 3.66 | Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model. ( Feola, J; Houchens, DP; Ovejera, AA; Slagel, DE, 1982) |
| "We investigated the effects of combinations of BCNU and misonidazole, and melphalan and misonidazole on growth delay in two human malignant melanoma xenograft lines grown in immune-deprived mice." | 3.66 | Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts. ( Clutterbuck, RD; McElwain, TJ; Millar, JL, 1982) |
| "Intracerebral murine glioma 26 was used as a model system for evaluating two-drug combinations of antitumor agents, BCNU was combined with either procarbazine, dianhydrogalactitol, or ellipticine." | 3.66 | Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens. ( Levin, VA; Wilson, CB, 1978) |
| "The therapeutic usefulness of chlorpromazine (CPZ) and caffeine (CAF) in combination with selected nitrosoureas was investigated in mice bearing L1210 leukemia, Lewis lung carcinoma, and B16 melanoma." | 3.66 | Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors. ( Dykes, DJ; Laster, WR; Rose, WC; Schabel, FM; Trader, MW, 1978) |
| " BCNU delivered from the MEMS device showed dose-dependent inhibiting effect on the tumor growth in the BCNU dosage range of 0." | 1.33 | In vivo delivery of BCNU from a MEMS device to a tumor model. ( Brem, H; Cima, MJ; Ho Duc, HL; Langer, R; Li, Y; Tupper, M; Tyler, B; Williams, T, 2005) |
| " Pharmacokinetic studies indicated a rapid clearance of L-histidinol following a bolus dose (250 mg/kg i." | 1.28 | L-histidinol: preclinical therapeutic studies in combination with antitumor agents and pharmacokinetic studies in mice. ( Dykes, D; Malspeis, L; Plowman, J; Waud, W; Zaharko, D, 1992) |
| "Beneficial antitumor effects of low-dose chemotherapy (Adriamycin, BCNU, cisplatin, 5-fluorouracil, methotrexate, 6-thioguanine or vincristine) combined with an immunotherapy with a partially purified polysaccharide of Viva-Natural, an edible seaweed extract, have been demonstrated against intraperitoneally implanted Lewis lung carcinoma in syngeneic mice." | 1.28 | Antitumor potential of low-dose chemotherapy manifested in combination with immunotherapy of Viva-Natural, a dietary seaweed extract, on Lewis lung carcinoma. ( Furusawa, E; Furusawa, S, 1990) |
| "Two human brain tumors which were previously established in nude mice were used to determine antitumor efficacy of various therapeutic agents." | 1.27 | Human brain tumor xenografts in nude mice as a chemotherapy model. ( Houchens, DP; Ovejera, AA; Riblet, SM; Slagel, DE, 1983) |
| "A previously published protocol for treating recurrent malignant gliomas with sequential courses of BCNU and 5-FU was partially planned based upon these initial observations." | 1.27 | Improved treatment of a brain-tumor model. Part 2: Sequential therapy with BCNU and 5-fluorouracil. ( Dougherty, DV; Gerosa, MA; Rosenblum, ML; Wilson, CB, 1983) |
| " Log-linear tumor cell kill was also obtained over a wide dosage range with several alkylating agents in murine tumors treated in vivo." | 1.27 | Preclinical studies and clinical correlation of the effect of alkylating dose. ( Cathcart, KN; Frei, E; Holden, SA; Teicher, BA; Wang, YY, 1988) |
| "Vitamin A, whether combined with various cytotoxic drugs or not, did not show, when different experimental schedules were used, an anti-tumour effect on various murine tumours." | 1.27 | Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not. ( Bresson, ML; Cattan, A, 1986) |
| "A dose-response relation for the cytotoxic activity of chloroethylnitrosourea cancer chemotherapeutic agents in cell culture has been developed." | 1.26 | Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture. ( Deen, DF; Weinkam, RJ, 1982) |
| "Murine LPC-1 plasmacytoma is sensitive to treatment with cyclophosphamide (CY), and animals bearing this tumor in advanced stages can be cured with doses as small as 60 mg/kg." | 1.26 | Development and characterization of a cyclophosphamide-resistant mouse plasmacytoma cell line. ( Frondoza, CG; Humphrey, RL; Trivedi, SM, 1982) |
| " The shape of the DAG dose-response curves was similar to that of those observed for most oncolytic agents." | 1.26 | Chemotherapeutic approaches to brain tumors. Experimental observations with dianhydrogalactitol and dibromodulcitol. ( Levin, VA; Wheeler, KT, 1982) |
| "A clonogenic cell assay for malignant brain tumors that permits the evaluation of tumor cell sensitivity to BCNU and that correlates with patient response to BCNU has been developed." | 1.26 | Potentials and possible pitfalls of human stem cell analysis. ( Dougherty, DV; Reese, C; Rosenblum, ML; Wilson, CB, 1981) |
| "HN2 was a potent carcinogen, producing squamous cell carcinomas in 9 of 33 mice in 1 series." | 1.26 | Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice. ( Smuckler, EA; Zackheim, HS, 1980) |
| "Human malignant melanoma was transplanted to the cheek pouch of immunosuppressed (corticosteroid-treated) hamsters." | 1.26 | Chemotherapy against human melanoma in the hamster cheek pouch. ( Dufour, FD; Mah, SG; Morton, DL; Okada, GT, 1980) |
| "Experiments are described in which dose-response data have been obtained for EMT6 mouse tumour cells growing in vivo and exposed to various cytotoxic agents." | 1.26 | The sensitivity to cytotoxic agents of the EMT6 tumor in vivo. Comparative response of lung nodules in rapid expotential growth and of the solid flank tumour. ( Bleehen, NM; Twentyman, PR, 1976) |
| " An additional effect with ADR was the apparent elimination of heat-induced thermal tolerance at toxic drug doses." | 1.26 | The interaction of thermal tolerance with drug cytotoxicity in vitro. ( Bleehen, NM; Honess, DJ; Morgan, JE, 1979) |
| "Seven human brain tumors were transplanted into the brains (6/7 takes) and subcutaneous tissues (7/7 takes) of athymic nude mice." | 1.26 | Human brain tumor transplantation into nude mice. ( Basler, GA; Chernik, NL; Posner, JB; Shapiro, WR, 1979) |
| "Schmidt-Ruppin strain of Rous Sarcoma was inoculated intracerebrally into 27 newborn beagle dogs." | 1.26 | BCNU and steroids in the viral-induced dog brain tumor. ( Brisman, R; Gamboa, E; Goldberg, N; Hilal, S; Michelsen, JW; Schlesinger, EB; Willson, N, 1979) |
| "The efficacy of glucan in combination with local radiation therapy was measured using three solid murine tumors of differing abilities to induce a host defense." | 1.26 | Preliminary observations on the effect of glucan in combination with radiation and chemotherapy in four murine tumors. ( Perez, CA; Stewart, CC; Valeriote, FA, 1978) |
| "Pretreatment with phenytoin, sodium methylprednisolone succinate and dexamethasone had little or no effect." | 1.26 | The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p ( Byrd, A; Finn, A; Levin, VA; Stearns, J; Weinkam, RJ, 1979) |
| " Dose-response curves showed that the inhibitory responses after 1 day in these pretreated cultures exposed to 0." | 1.26 | Combined growth-inhibitory responses and ultrastructural alterations produced by 1,3-bis(2-chloroethyl)-1-nitrosourea and dexamethasone in rat glioma cell cultures. ( Boler, RK; Grasso, RJ; Johnson, CE; Moore, NA, 1977) |
| " A comparison of the in vitro colony-forming capacity of treated and untreated tumor cells permits calculation of the fraction of clonogenic tumor cells surviving in vivo therapy; The plateau that we previously observed o the BCNU dose-response curve is not the result of repair of potentially lethal damage, since no change in the 0." | 1.26 | Brain-tumor therapy. Quantitative analysis using a model system. ( Knebel, KD; Rosenblum, MK; Vasquez, DA; Wilson, CB, 1977) |
| " This dosage is about four times that used in a single course in treating humans." | 1.26 | Cytotoxic effects of 1,3-bis(2 chloroethyl)-1-nitrosourea (BCNU) on cultured human glioblastomas. ( Pinkerton, H; Rana, MW, 1976) |
| " The three drugs show similar threshold-type dose-response survival curves on asynchronous cells treated for 1 hr." | 1.26 | A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells. ( Drewinko, B; Gottlieb, JA; Loo, TL, 1976) |
| "Survival curves are presented for the treatment of B16 melanomas with a range of single doses of cyclophosphamide (CY), 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU), or 1-(2-chloroethyl)-3-trans-4-methylcyclohexyl)-1-nitro-sourea (MeCCNU)." | 1.25 | The response of hypoxic B16 melanoma cells to in vivo treatment with chemotherapeutic agents. ( Hill, RP; Stanley, JA, 1975) |
| " The BCNU dose-response curve was exponential up to a dose of 0." | 1.25 | In vitro evaluation of in vivo brain tumor chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Barker, M; Knebel, KD; Rosenblum, ML; Wheeler, KT; Wilson, CB, 1975) |
| "The shape of dose-response curves obtained for asynchronous, exponentially growing 9L rat brain tumor cells treated in vitro with 1,3-bis(2-chloroethyl)-1-nitrosourea changed as a function of the drug exposure time." | 1.25 | Factors influencing the survival of rat brain tumor cells after in vitro treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Kabra, PM; Levin, VA; Sheppard, S; Tel, N; Wheeler, KT; Williams, ME, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 169 (88.95) | 18.7374 |
| 1990's | 10 (5.26) | 18.2507 |
| 2000's | 8 (4.21) | 29.6817 |
| 2010's | 3 (1.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Montgomery, JA | 1 |
| McCaleb, GS | 1 |
| Johnston, TP | 2 |
| Mayo, JG | 2 |
| Laster, WR | 5 |
| Smith, RH | 1 |
| Scudiero, DA | 1 |
| Michejda, CJ | 1 |
| Roger, P | 1 |
| Monneret, C | 1 |
| Fournier, JP | 1 |
| Choay, P | 1 |
| Gagnet, R | 1 |
| Gosse, C | 1 |
| Letourneux, Y | 1 |
| Atassi, G | 3 |
| Gouyette, A | 1 |
| Crider, AM | 2 |
| Kolczynski, TM | 1 |
| Yates, KM | 1 |
| Lamey, R | 1 |
| Floss, HG | 1 |
| Cassady, JM | 1 |
| Bradner, WJ | 1 |
| Riolobos, L | 1 |
| Gad, EA | 1 |
| Treuting, PM | 1 |
| Timms, AE | 1 |
| Hershberg, EA | 1 |
| Corulli, LR | 1 |
| Rodmaker, E | 1 |
| Disis, ML | 1 |
| Ohba, S | 1 |
| Hirose, Y | 1 |
| Yoshida, K | 1 |
| Yazaki, T | 1 |
| Kawase, T | 1 |
| Zhong, Z | 1 |
| Wan, Y | 1 |
| Shi, S | 1 |
| Han, J | 1 |
| Zhang, Z | 1 |
| Sun, X | 1 |
| Branle, F | 1 |
| Lefranc, F | 1 |
| Camby, I | 1 |
| Jeuken, J | 1 |
| Geurts-Moespot, A | 1 |
| Sprenger, S | 1 |
| Sweep, F | 1 |
| Kiss, R | 1 |
| Salmon, I | 1 |
| Shi, MG | 1 |
| Huang, Q | 1 |
| Dong, J | 1 |
| Sun, ZF | 1 |
| Lan, Q | 1 |
| Kokkinakis, DM | 1 |
| Ahmed, MM | 1 |
| Chendil, D | 1 |
| Moschel, RC | 1 |
| Pegg, AE | 1 |
| Steele, TA | 1 |
| Hauser, CC | 1 |
| Li, Y | 1 |
| Ho Duc, HL | 1 |
| Tyler, B | 1 |
| Williams, T | 1 |
| Tupper, M | 1 |
| Langer, R | 1 |
| Brem, H | 2 |
| Cima, MJ | 1 |
| Sampath, P | 1 |
| Rhines, LD | 1 |
| DiMeco, F | 1 |
| Tyler, BM | 1 |
| Park, MC | 1 |
| Hunyadi, J | 1 |
| Szegedi, G | 1 |
| Szabo, T | 1 |
| Ahmed, A | 1 |
| Laki, K | 1 |
| Muraoka, I | 1 |
| Hoshino, T | 6 |
| Ogashiwa, M | 1 |
| Weizsaecker, M | 1 |
| Deen, DF | 6 |
| Rosenblum, ML | 6 |
| Gutin, PH | 1 |
| Barker, M | 5 |
| Nomura, K | 2 |
| Pentecost, SM | 1 |
| Vats, TS | 1 |
| Kimler, BF | 1 |
| Henderson, SD | 1 |
| Morantz, RA | 1 |
| Hahn, GM | 2 |
| Kokunai, T | 5 |
| Kuwamura, K | 5 |
| Li, DJ | 1 |
| Schold, SC | 2 |
| Bigner, DD | 6 |
| Mahaley, MS | 3 |
| Steinbok, P | 3 |
| Aronin, P | 1 |
| Dudka, L | 1 |
| Zinn, D | 1 |
| Serano, RD | 1 |
| Sigel, CW | 1 |
| Nichol, CA | 1 |
| Hanna, MG | 1 |
| Key, ME | 1 |
| Arrick, BA | 2 |
| Nathan, CF | 2 |
| Bjerkvig, R | 1 |
| Oredsson, SM | 1 |
| Marton, LJ | 3 |
| Linden, M | 1 |
| Tofilon, PJ | 1 |
| Buckley, N | 1 |
| Houchens, DP | 3 |
| Ovejera, AA | 2 |
| Riblet, SM | 1 |
| Slagel, DE | 2 |
| Honess, DJ | 3 |
| Bleehen, NM | 6 |
| Levin, VA | 7 |
| Hervatin, SJ | 1 |
| Koch-Weser, J | 1 |
| McCann, PP | 1 |
| Sjoerdsma, A | 1 |
| Gerosa, MA | 1 |
| Dougherty, DV | 2 |
| Wilson, CB | 9 |
| Liu, LH | 1 |
| Refojo, MF | 1 |
| Ni, C | 1 |
| Ueno, N | 1 |
| Albert, DM | 1 |
| Weizsäcker, M | 1 |
| Nagamune, A | 1 |
| Winkelströter, R | 1 |
| Vieten, H | 1 |
| Wechsler, W | 1 |
| Dumont, P | 1 |
| Tagnon, HJ | 1 |
| Dougherty, DA | 1 |
| Wheeler, KT | 14 |
| Wallen, CA | 4 |
| Wright, DC | 1 |
| Landahl, HD | 1 |
| Patlak, CS | 1 |
| Csejtey, J | 1 |
| Herman, TS | 2 |
| Sweets, CC | 1 |
| White, DM | 1 |
| Gerner, EW | 1 |
| Zeller, WJ | 3 |
| Ivankovic, S | 1 |
| Habs, M | 3 |
| Schmähl, D | 4 |
| DiStefano, JF | 1 |
| Beck, G | 1 |
| Lysik, R | 1 |
| Zucker, S | 1 |
| Siemann, DW | 2 |
| Cassone, A | 1 |
| Bistoni, F | 1 |
| Cenci, E | 1 |
| Pesce, CD | 1 |
| Tissi, L | 1 |
| Marconi, P | 1 |
| Weinkam, RJ | 2 |
| Feola, J | 2 |
| Clutterbuck, RD | 1 |
| Millar, JL | 1 |
| McElwain, TJ | 1 |
| Frondoza, CG | 1 |
| Trivedi, SM | 1 |
| Humphrey, RL | 1 |
| Cowen, DM | 1 |
| Siegerstetter, J | 1 |
| Janik, AC | 1 |
| Double, JA | 1 |
| Maruyama, Y | 4 |
| Williams, A | 1 |
| Feola, JM | 1 |
| Nava, C | 1 |
| Tamaki, N | 1 |
| Matsumoto, S | 1 |
| Fiebig, HH | 2 |
| Strobel, H | 1 |
| Gibson, NW | 2 |
| Hickman, JA | 2 |
| Budzyński, W | 1 |
| Ghanta, VK | 2 |
| Hiramoto, RN | 2 |
| Davis, DW | 1 |
| Hiramoto, NS | 1 |
| Kaufman, K | 4 |
| Spence, AM | 1 |
| Geraci, JP | 1 |
| Drago, JR | 1 |
| Goldman, LB | 1 |
| Worgul, T | 1 |
| Gershwin, ME | 1 |
| Bertram, JS | 1 |
| Janik, P | 1 |
| Giuliani, FC | 1 |
| Zirvi, KA | 1 |
| Kaplan, NO | 1 |
| Goldin, A | 3 |
| Murray, HW | 1 |
| DeSantis, NM | 1 |
| Cohn, ZA | 1 |
| Bullard, DE | 1 |
| Bigner, SH | 1 |
| Furusawa, E | 2 |
| Lockwood, RH | 1 |
| Schmitz, R | 2 |
| Hüper, J | 1 |
| Pichlmayr, R | 1 |
| Eisenbrand, G | 2 |
| Reese, C | 1 |
| Nicolson, GL | 1 |
| Lotan, R | 1 |
| Rios, A | 1 |
| Tel, E | 1 |
| Allen, N | 1 |
| U, R | 2 |
| Varia, MA | 1 |
| Lipper, S | 2 |
| Mahaley, J | 1 |
| Dalzell, JG | 1 |
| Zackheim, HS | 1 |
| Smuckler, EA | 1 |
| Shafer, RH | 1 |
| Chase, ES | 1 |
| Dufour, FD | 1 |
| Okada, GT | 1 |
| Mah, SG | 1 |
| Morton, DL | 1 |
| Greco, C | 1 |
| Calabresi, F | 1 |
| Corsi, A | 1 |
| Pericoli, N | 1 |
| Caputo, M | 1 |
| Knorr, V | 1 |
| Aabo, K | 1 |
| Ross, BD | 1 |
| Zhao, YJ | 1 |
| Neal, ER | 1 |
| Stegman, LD | 1 |
| Ercolani, M | 1 |
| Ben-Yoseph, O | 1 |
| Chenevert, TL | 1 |
| Miller, BE | 1 |
| Delmonico, L | 1 |
| Vistisen, K | 1 |
| Miller, FR | 1 |
| Frei, E | 2 |
| Ara, G | 1 |
| Teicher, B | 1 |
| Bunnell, C | 1 |
| Richardson, P | 1 |
| Wheeler, C | 1 |
| Tew, K | 1 |
| Elias, A | 1 |
| Chen, Z | 1 |
| Panasci, LC | 1 |
| Carter, CA | 1 |
| Cohen, SC | 1 |
| Gabelnick, HL | 1 |
| Johnson, RK | 1 |
| Twentyman, PR | 5 |
| Finklestein, JZ | 1 |
| Tittle, K | 1 |
| Rubenstein, J | 1 |
| Meshnik, R | 1 |
| Weiner, J | 1 |
| Sufrin, G | 2 |
| Murphy, GP | 1 |
| Iwaguchi, T | 1 |
| Kitagawa, H | 1 |
| Mabel, JA | 1 |
| Merker, PC | 1 |
| Sturgeon, ML | 1 |
| Wodinsky, I | 1 |
| Geran, RI | 1 |
| Morgan, JE | 2 |
| Marmor, JB | 1 |
| Bellet, RE | 1 |
| Danna, V | 1 |
| Mastrangelo, MJ | 1 |
| Berd, D | 1 |
| Schabel, FM | 9 |
| Baril, BB | 1 |
| Baril, EF | 1 |
| Laszlo, J | 1 |
| Wheeler, GP | 3 |
| Bast, RC | 1 |
| Segerling, M | 1 |
| Ohanian, SH | 1 |
| Greene, SL | 1 |
| Zbar, B | 1 |
| Rapp, HJ | 1 |
| Borsos, T | 1 |
| Bono, VH | 1 |
| Miyahara, M | 2 |
| Nakadate, M | 1 |
| Suzuki, I | 1 |
| Ishidate, M | 1 |
| Odashima, S | 1 |
| Shapiro, WR | 2 |
| Basler, GA | 1 |
| Chernik, NL | 1 |
| Posner, JB | 1 |
| Zinn, DC | 1 |
| Mahaley, JL | 1 |
| Brisman, R | 1 |
| Schlesinger, EB | 1 |
| Willson, N | 1 |
| Hilal, S | 1 |
| Michelsen, JW | 1 |
| Gamboa, E | 1 |
| Goldberg, N | 1 |
| Stylos, WA | 1 |
| Chirigos, MA | 2 |
| Lengel, CR | 1 |
| Trader, MW | 3 |
| Witt, MH | 1 |
| Drewinko, B | 2 |
| Loo, TL | 2 |
| Freireich, EJ | 1 |
| Ehmann, UK | 1 |
| Corbett, TH | 1 |
| Griswold, DP | 2 |
| Wolpert, MK | 1 |
| Venditti, JM | 1 |
| Bonmassar, A | 1 |
| Williams, ME | 2 |
| Feldstein, M | 1 |
| Baker, DG | 1 |
| Hemsworth, GR | 1 |
| Wolff, JS | 1 |
| Kraska, AR | 1 |
| Jensen, KE | 1 |
| Donaldson, J | 1 |
| Stewart, CC | 2 |
| Beetham, KL | 1 |
| Walker, MD | 2 |
| Valeriote, FA | 1 |
| Perez, CA | 1 |
| Rose, WC | 1 |
| Dykes, DJ | 2 |
| Fry, FJ | 1 |
| Johnson, LK | 1 |
| Stearns, J | 1 |
| Byrd, A | 1 |
| Finn, A | 1 |
| Epstein, JH | 1 |
| Schenken, LL | 1 |
| Grasso, RJ | 1 |
| Johnson, CE | 1 |
| Boler, RK | 1 |
| Moore, NA | 1 |
| Rosenblum, MK | 1 |
| Knebel, KD | 3 |
| Vasquez, DA | 2 |
| Jones, MT | 1 |
| Woodard, DA | 1 |
| Durant, JR | 2 |
| Stanley, JA | 2 |
| Shipley, WU | 1 |
| Steel, GG | 2 |
| Deutsch-Wenzel, T | 1 |
| Hilton, J | 1 |
| Raju, MR | 1 |
| Bains, E | 1 |
| Jett, J | 1 |
| Murphy, P | 1 |
| Adams, K | 1 |
| Stanley, J | 1 |
| Wheeler, K | 1 |
| Rosenblum, M | 1 |
| Wasserman, TH | 1 |
| Slavik, M | 1 |
| Carter, SK | 3 |
| Hill, RP | 1 |
| Hiramoto, R | 1 |
| Ghanta, V | 1 |
| Pezzotta, S | 1 |
| Agradi, E | 1 |
| Paoletti, P | 1 |
| Tel, N | 1 |
| Sheppard, S | 1 |
| Kabra, PM | 1 |
| Bonmassar, E | 1 |
| Fioretti, MC | 2 |
| Mohr, SJ | 1 |
| Fuhrman, FS | 1 |
| Pryor, JW | 1 |
| Pinkerton, H | 1 |
| Rana, MW | 1 |
| Gottlieb, JA | 1 |
| Wong, KH | 4 |
| Urano, M | 1 |
| Zaharko, D | 1 |
| Plowman, J | 1 |
| Waud, W | 1 |
| Dykes, D | 1 |
| Malspeis, L | 1 |
| Zhang, H | 1 |
| Teicher, BA | 3 |
| Holden, SA | 3 |
| Furusawa, S | 1 |
| Deichman, GI | 1 |
| Kashleva, HA | 1 |
| Kluchareva, TE | 1 |
| Matveeva, VA | 1 |
| Nagarkatti, M | 2 |
| Toney, DM | 1 |
| Nagarkatti, PS | 2 |
| Bernal, SD | 1 |
| Cathcart, KN | 2 |
| Wang, YY | 1 |
| Seth, A | 1 |
| Puccetti, P | 1 |
| Romani, L | 1 |
| Cattan, A | 1 |
| Bresson, ML | 1 |
| Lijinsky, W | 1 |
| Kovatch, RM | 1 |
| Singer, SS | 1 |
| Mulcahy, RT | 1 |
| Jeney, A | 1 |
| Kopper, L | 1 |
| Nagy, P | 1 |
| Lapis, K | 1 |
| Süli-Vargha, H | 1 |
| Medzihradszky, K | 1 |
| Stevens, MF | 1 |
| Langdon, SP | 1 |
| Fizames, C | 1 |
| Lavelle, F | 1 |
| Lunt, E | 1 |
| Tilson, RM | 1 |
| Sigel, MM | 1 |
| Lichter, W | 1 |
| Lopez, DM | 1 |
| Inaba, M | 1 |
| Sakurai, Y | 1 |
| Skipper, HE | 1 |
| Cheeks, JB | 1 |
| Broder, LE | 1 |
| Zubrod, CG | 1 |
| Scott, MT | 1 |
| Weiss, Ede C | 1 |
| Cravioto, H | 1 |
| Weiss, JF | 1 |
| Ransohoff, J | 1 |
| Teller, MN | 1 |
| Bowie, M | 1 |
| Mountain, IM | 1 |
| Alexander, JA | 1 |
| Andrews, CM | 1 |
14 reviews available for carmustine and Experimental Neoplasms
| Article | Year |
|---|---|
Glutathione metabolism as a determinant of therapeutic efficacy: a review.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Biological Transport; Carmustine; Cycloph | 1984 |
[Colony forming efficiency assay and human tumor (author's transl)].
Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Gl | 1981 |
Potentiation of chemotherapy by hypoxic cell radiation sensitizers--a review.
Topics: Anaerobiosis; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Synergism; Lomustin | 1982 |
Cellular heterogeneity in malignant tumors. The importance of clonal interaction on tumor evolution, response to chemotherapy and metastatic ability evaluated in experimental systems.
Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Communication; Clone Cells; Humans; Mic | 1996 |
Interactions of hyperthermia and chemotherapy in animals.
Topics: Alkylating Agents; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bleomycin; Carmu | 1979 |
Rationale for adjuvant chemotherapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cyclophosphamide; Cytarabine; Doxorubi | 1977 |
Review of mechanism of action studies of the nitrosoureas.
Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Cell Survival | 1976 |
Patterns of resistance and therapeutic synergism among alkylating agents.
Topics: Alkylating Agents; Animals; Carmustine; Cell Survival; Cyclophosphamide; Drug Resistance; Drug Syner | 1978 |
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, | 1976 |
Clinical comparison of the nitrosoureas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carmustine; Chemical Phenomena; C | 1975 |
Chemical xenogenization of experimental tumors.
Topics: Animals; Antigens, Neoplasm; Carmustine; Cell Line; Dacarbazine; DNA; Histocompatibility Antigens; I | 1987 |
1,3-bis(2-chloroethyl)-1-nitrosourea (bcnu) and other nitrosoureas in cancer treatment: a review.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Carmustine; Cell Line; Cell-Free System; | 1972 |
Present status of cancer chemotherapy.
Topics: Alkylating Agents; Animals; Anti-Bacterial Agents; Antimetabolites; Carmustine; DNA, Neoplasm; Evalu | 1974 |
Corynebacterium parvum as an immunotherapeutic anticancer agent.
Topics: Animals; Carmustine; Corynebacterium; Humans; Immunity; Immunity, Cellular; Immunotherapy; Lectins; | 1974 |
2 trials available for carmustine and Experimental Neoplasms
| Article | Year |
|---|---|
Immunobiology of primary intracranial tumors. Part 4: levamisole as an immune stimulant in patients and in the ASV glioma model.
Topics: Adjuvants, Immunologic; Alpharetrovirus; Animals; Brain Neoplasms; Carmustine; Clinical Trials as To | 1981 |
1,3-bis(2-chloroethyl)-1-nitrosourea (bcnu) and other nitrosoureas in cancer treatment: a review.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Carmustine; Cell Line; Cell-Free System; | 1972 |
175 other studies available for carmustine and Experimental Neoplasms
| Article | Year |
|---|---|
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimen | 1977 |
1,3-Dialkyl-3-acyltriazenes, a novel class of antineoplastic alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Half-Life; Mice; M | 1990 |
Rationale for the synthesis and preliminary biological evaluation of highly active new antitumor nitrosoureido sugars.
Topics: Amino Sugars; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Drug Evaluation, Precli | 1989 |
Synthesis and anticancer activity of nitrosourea derivatives of phensuximide.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Leukemia L1210; Mice; Neoplasms, Experi | 1980 |
Synthesis of nitrosourea derivatives of pyridine and piperidine as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Leukemia, Experimental; Leukopenia; Mice; Neoplasms, Experimental; N | 1980 |
The Effect of Mouse Strain, Sex, and Carcinogen Dose on Toxicity and the Development of Lung Dysplasia and Squamous Cell Carcinomas in Mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Carmustine; Cell Transformation, Neoplastic; Dose-Re | 2019 |
Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzoquinones; Carmustine; Cell Cycle; Cell L | 2010 |
Co-delivery of adenovirus and carmustine by anionic liposomes with synergistic anti-tumor effects.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Chemoki | 2012 |
Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Deletion; Chromosome | 2002 |
[Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Carmustine; Cell Cy | 2002 |
Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Dacarba | 2003 |
The role of interferon-alpha in a successful murine tumor therapy.
Topics: Animals; Antibodies; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Prolifera | 2005 |
In vivo delivery of BCNU from a MEMS device to a tumor model.
Topics: Animals; Antineoplastic Agents, Alkylating; Carbon Radioisotopes; Carmustine; Chemistry, Pharmaceuti | 2005 |
Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma.
Topics: Absorbable Implants; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmu | 2006 |
Increased cytotoxic sensitivity of YPC-1 tumor cells from mice treated with nitrosoureas.
Topics: Animals; Carmustine; Cytotoxicity, Immunologic; Female; Fibrinogen; gamma-Glutamyltransferase; Immun | 1981 |
[Effects of surgery on remaining brain tumor cells (author's transl)].
Topics: Animals; Brain Neoplasms; Carmustine; Mitosis; Neoplasms, Experimental; Rats; Time Factors | 1980 |
The 9L rat brain tumor: description and application of an animal model.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Neoplasm Transp | 1981 |
Post-treatment kinetics of BCNU in a 9L rat brain tumor model.
Topics: Animals; Brain Neoplasms; Carmustine; Glioma; Kinetics; Male; Neoplasms, Experimental; Rats | 1981 |
Combination chemotherapy for the 9L rat brain tumor model system.
Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Carmustine; Drug Administration Schedule | 1982 |
Does the mode of heat induction modify drug anti-tumour effects?
Topics: Animals; Bleomycin; Carmustine; Fibrosarcoma; Hindlimb; Hot Temperature; Mice; Mice, Inbred C3H; Neo | 1982 |
[Effect of perfluorochemicals on BCNU chemotherapy in a 9L rat brain tumor model].
Topics: Animals; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorocarbons; Glioma; Male; Neopla | 1982 |
Responses of RIF tumors to heat and drugs: dependence on tumor size.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Combined Modality Th | 1984 |
Treatment of five subcutaneous human glioma tumor lines in athymic mice with carmustine, procarbazine, and mithramycin.
Topics: Animals; Carmustine; Disease Models, Animal; Drug Therapy, Combination; Glioma; Humans; Mice; Mice, | 1983 |
Biology of gliomas: potential clinical implications of glioma cellular heterogeneity.
Topics: Adult; Aged; Animals; Brain Neoplasms; Carmustine; Cell Line; Female; Glioblastoma; Glioma; Humans; | 1981 |
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model.
Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Carmustine; Drug Therapy, Combination; Glioma | 1982 |
Immunotherapy of metastases enhances subsequent chemotherapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; BCG Vaccine; Carcinoma, Hepatocellular; Carmusti | 1982 |
Cell cycle age response of 9L cells to 1,3-bis(2-chloroethyl)-1-nitrosourea and modification by alpha-difluoromethylornithine.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Eflornithine; Ki | 1983 |
Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids.
Topics: Animals; Carmustine; Cell Division; Cells, Cultured; Drug Resistance; Male; Neoplasms, Experimental; | 1984 |
Human brain tumor xenografts in nude mice as a chemotherapy model.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Humans; | 1983 |
Sensitivity of normal mouse marrow and RIF-1 tumour to hyperthermia combined with cyclophosphamide or BCNU: a lack of therapeutic gain.
Topics: Bone Marrow; Bone Marrow Transplantation; Carmustine; Cell Survival; Clone Cells; Colony-Forming Uni | 1982 |
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Topics: Animals; Brain Neoplasms; Carmustine; Drug Administration Schedule; Drug Synergism; Drug Therapy, Co | 1981 |
An approach to the use of polyamine inhibitors for cancer therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Ef | 1981 |
Improved treatment of a brain-tumor model. Part 2: Sequential therapy with BCNU and 5-fluorouracil.
Topics: Animals; Brain Neoplasms; Carmustine; Clone Cells; Disease Models, Animal; Drug Therapy, Combination | 1983 |
Sustained release of carmustine (BCNU) for treatment of experimental intraocular malignancy.
Topics: Animals; Anterior Chamber; Carmustine; Cricetinae; Delayed-Action Preparations; Eye Neoplasms; Femal | 1983 |
Radiation and drug response of the rat glioma RG2.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Glioma; Male; Neopl | 1982 |
Combination chemotherapy with AMSA on L1210 leukaemia and B16 melanoma.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Carmustine; Dacarbazine; Drug Therapy, Co | 1981 |
Rational planning of brain tumour therapy based on laboratory investigations: comparison of single- and multiple-dose BCNU schedules.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Administration Schedule; Glioma; Humans; N | 1980 |
Is cell survival a determinant of the in situ response of 9L tumours?
Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Ra | 1980 |
In situ drug delivery.
Topics: Animals; Capillaries; Carmustine; Half-Life; Misonidazole; Models, Biological; Neoplasms, Experiment | 1980 |
Bischloroethyl nitrosourea (BCNU).
Topics: Abnormalities, Drug-Induced; Animals; Carcinogens; Carmustine; Chemical Phenomena; Chemistry; Drug I | 1981 |
Effect of heating on lethality due to hyperthermia and selected chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Cells, Cultured; Cisplatin; Cricetinae; C | 1982 |
Experimental chemical production of brain tumors.
Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Methylnitrosourea; Neoplasms, Experimental; | 1982 |
Pharmacological studies comparing the mechanism of tumor-induced and activated macrophage-induced bone marrow cytolysis.
Topics: Animals; Bone Marrow Cells; Carmustine; Catalase; Cycloheximide; Cytotoxicity, Immunologic; Dactinom | 1980 |
Immunopotentiation of anticancer chemotherapy by Candida albicans, other yeasts and insoluble glucan in an experimental lymphoma model.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Candida albicans; Carmustine; Cell Wall; Cry | 1982 |
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Respon | 1982 |
Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model.
Topics: Animals; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Glioma; Humans; Medullob | 1982 |
Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Cell Line; Drug Synergism; Drug Therapy, Co | 1982 |
Development and characterization of a cyclophosphamide-resistant mouse plasmacytoma cell line.
Topics: Animals; Carmustine; Cell Division; Cell Line; Clone Cells; Cyclophosphamide; DNA, Neoplasm; Drug Re | 1982 |
Chemotherapeutic approaches to brain tumors. Experimental observations with dianhydrogalactitol and dibromodulcitol.
Topics: Animals; Brain Neoplasms; Carmustine; Cells, Cultured; Dianhydrogalactitol; Drug Therapy, Combinatio | 1982 |
The assessment of response of murine transplantable colon tumors to combination chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carmustine; Cell Line; Colonic Neoplasms; Dimethylhy | 1982 |
Evidence for host resistance in 1,3 bis(2-chloroethyl)-1-nitrosourea treatment induced in syngeneic LSA lymphoma.
Topics: Animals; Carmustine; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Female; Immunity, I | 1982 |
Synergistic effect of perfluorochemicals on BCNU chemotherapy. Experimental study in a 9L rat brain-tumor model.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Synergism; Drug Therapy, Combinati | 1982 |
[Effect of perfluorochemicals on BCNU chemotherapy in a rat brain-tumor model].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Synergism; Fluorocarbons; Glioma; | 1982 |
Experimental chemotherapy with N'N'-bis(2-chloroethyl)-N-nitrosourea (BCNU) in autochthonous neurogenic tumors of the rat transplacentally induced by ethylnitrosourea.
Topics: Animals; Carmustine; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchang | 1982 |
The role of isocyanates in the toxicity of antitumour haloalkylnitrosoureas.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyanates; Female; Leukemia L1210; Lomustine; Lymphoma; M | 1982 |
Effect of perfluorochemicals on BCNU chemotherapy: preliminary study in a rat brain tumor model.
Topics: Animals; Brain; Brain Neoplasms; Carmustine; Drug Combinations; Drug Therapy, Combination; Fluorocar | 1982 |
[Possibility of the use of perfluorochemicals (fluorocarbons) as adjuvants in chemotherapy of cancer].
Topics: Animals; Blood Substitutes; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorocarbons; M | 1982 |
Lewis lung carcinoma in mice as an experimental therapy model. II. The effect of BCNU, cyclophosphamide and/or surgery treatment on early and advanced tumor in mice.
Topics: Animals; Carmustine; Cyclophosphamide; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasm Tr | 1982 |
Maintenance of MOPC 104E myeloma in plateau phase.
Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Cyclophosphamide; Dose-Response Relationship, | 1980 |
Influence of fractionation schedules on the response of a rat brain tumor to therapy with BCNU and radiation.
Topics: Animals; Brain Neoplasms; Carmustine; Chemical Fractionation; Dose-Response Relationship, Drug; Dose | 1980 |
Combined cyclotron fast-neutron and BCNU therapy in a rat brain-tumor model.
Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Dose | 1981 |
Therapy for Nb rat tumor transplanted in athymic mice.
Topics: Adenocarcinoma; Androgens; Animals; Carmustine; Dactinomycin; Male; Mice; Mice, Nude; Neoplasm Metas | 1981 |
Establishment of a cloned line of Lewis Lung Carcinoma cells adapted to cell culture.
Topics: Animals; Carmustine; Cell Line; Clone Cells; Graft Survival; Humans; Lung Neoplasms; Methotrexate; M | 1980 |
Efficacy of continuous treatment with radiation in a rat brain-tumor model.
Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Male; Neoplasms, Experimental; Radiati | 1981 |
Chemotherapy of human colorectal tumor xenografts in athymic mice with clinically active drugs: 5-fluorouracil and 1-3-bis-(-2-chloroethyl)-1-nitrosourea (BCNU). Comparison with doxorubicin derivatives: 4'deoxydoxorubicin and 4'-O-methyldoxorubicin.
Topics: Adenocarcinoma; Animals; Carmustine; Colonic Neoplasms; Doxorubicin; Fluorouracil; Humans; Mice; Mic | 1981 |
Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis.
Topics: Animals; Carmustine; Catalase; Cytotoxicity, Immunologic; Female; Glutathione; Glutathione Peroxidas | 1981 |
Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Disease Models, Animal; Glioma; Mice; Mice, Nude; N | 1981 |
Therapeutic activity of pretazettine on Lewis lung carcinoma.
Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antineoplastic Agents; Carmustine; Doxorubicin; Drug T | 1981 |
Studies in an animal model on the effectiveness of adjuvant chemotherapy with 5-FU and BCNU in cases of colorectal adenocarcinoma.
Topics: Adenocarcinoma; Animals; Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluoroura | 1981 |
Brain tumor therapy: prospects for combining BCNU with conventional radiotherapy schedules.
Topics: Animals; Brain Neoplasms; Carmustine; Cesium Radioisotopes; Gamma Rays; Male; Neoplasms, Experimenta | 1981 |
Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
Topics: Animals; Antineoplastic Agents; Carcinogens; Carmustine; Lomustine; Lung Neoplasms; Male; Neoplasms, | 1980 |
Potentials and possible pitfalls of human stem cell analysis.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Aggregation; Cells, Cultured; Clone Cells; | 1981 |
Heterogeneous in vitro sensitivities of metastatic B16 melanoma sublines and clones to retinoic acid or BCNU.
Topics: Animals; Carmustine; Cell Line; Clone Cells; Drug Evaluation, Preclinical; Melanoma; Mice; Neoplasms | 1981 |
Review of factors influencing the response of experimental brain tumors to therapy.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Kinetics; Neoplasms, Experimental; Rats | 1981 |
Effect of surgery on BCNU chemotherapy in a rat brain tumor model.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Mitosis; Neoplasm Transplantation; Neoplasms, Expe | 1980 |
Experimental therapy of brain tumors.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Methods; Metronidazole; Misonidazole; Neoplasms, Ex | 1980 |
Treatment of autochthonous rat brain tumors with fractionated radiotherapy. The effects of graded radiation doses and of combined therapy with BCNU or steroids.
Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Glioma; Methylprednisolone; Neoplasms, | 1980 |
Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Carmustine; Lomustine; Mechlorethamine; Mice; Neopla | 1980 |
DNA damage in rat 9L cells treated with nitrogen mustard and 1,3-bis(2-chloroethyl)-1-nitrosourea assayed by viscoelastometry and S1 nuclease.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cross-Linking Reagents; Deoxyribonucleases; DNA, Ne | 1980 |
Chemotherapy against human melanoma in the hamster cheek pouch.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cheek; Cricetinae; Cyclophosphamide; Da | 1980 |
Chemotherapeutic activity and histopathologic feature of BCNU + 5-FU effect on Lewis lung carcinoma.
Topics: Animals; Carmustine; Drug Therapy, Combination; Fluorouracil; Lung; Lung Neoplasms; Mice; Neoplasms, | 1980 |
[Animal experiments using adjuvant 5-FU and BCNU chemotherapy in stomach cancer].
Topics: Animals; Carmustine; Drug Therapy, Combination; Fluorouracil; Mice; Mice, Inbred BALB C; Mice, Nude; | 1980 |
Contributions of cell kill and posttreatment tumor growth rates to the repopulation of intracerebral 9L tumors after chemotherapy: an MRI study.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Death; Cell Division; | 1998 |
Use of tumor lines with selectable markers in assessing the effect on experimental metastases of combination chemotherapy with alkylating agents.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carmusti | 1998 |
Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cell Survival; Cisp | 2000 |
[Expression of extraneuronal monoamine transporter gene and DNA repair gene vis-à-vis with antitumor efficacy of SarCNU in human tumor xenografts].
Topics: Animals; Antineoplastic Agents; Carmustine; Carrier Proteins; DNA Helicases; DNA Repair; DNA-Binding | 2001 |
Effects of antineoplastic agents on wound healing in mice.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Doxorubicin; | 1975 |
The sensitivity to cytotoxic agents of the EMT6 tumor in vivo. Comparative response of lung nodules in rapid expotential growth and of the solid flank tumour.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cell Line; Cell Survival; Cyclophosphamide; D | 1976 |
Combination chemotherapy in murine neuroblastoma.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Disease Models, Animal; Dox | 1976 |
Comparative chemosensitivity of exponential- versus plateau-phase cells in both in vitro model systems.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cell Division; Cell Survival; Cells, Cultured | 1976 |
Pharmacokinetic studies of a transplantable murine renal adenocarcinoma.
Topics: Adenocarcinoma; Animals; Bleomycin; Carmustine; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Eval | 1977 |
Effect of chemotherapeutic agents on the growth of rat bladder cancer, BC-47.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cytarabine; Doxorubicin; Fluorouracil; Mitomy | 1978 |
Combination chemotherapy against B16 melanoma: bleomycin/vinblastine, bleomycin/cis-diamminedichloroplatinum, 5-fluorouracil/BCNU and 5-fluorouracil/methyl-CCNU.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cisplatin; Dose-Response Relationship, Drug; | 1978 |
[Perturbation of cell kinetics on 9L rat brain tumor treated with BCNU, in vitro and in vivo (author's transl)].
Topics: Animals; Brain Neoplasms; Carmustine; Cells, Cultured; Kinetics; Mitosis; Neoplasms, Experimental; R | 1978 |
The interaction of thermal tolerance with drug cytotoxicity in vitro.
Topics: Animals; Bleomycin; Carmustine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Doxorubi | 1979 |
Chemotherapy studies in autochthonous rat tumors: carcinomas of the forestomach.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Dimethylnitrosamine; Drug Evaluation, Preclin | 1979 |
Evaluation of a "nude" mouse-human tumor panel as a predictive secondary screen for cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carmustine; Dacarbazine; Doxorubicin; Drug Evaluation, | 1979 |
Action of radiation or alkylating agents on LSA lymphoma during growth.
Topics: Alkylating Agents; Animals; Carmustine; Cell Survival; Cobalt Radioisotopes; Cyclophosphamide; Dose- | 1979 |
Host resistance to tumor after cure of advanced LSA lymphoma by treatment with BCNU and chlorozotocin.
Topics: Animals; Carmustine; Drug Therapy, Combination; Lymphoma; Male; Mice; Neoplasms, Experimental; Strep | 1979 |
Inhibition of rat liver DNA polymerase by nitrosoureas and isocyanates.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Cyanates; Cyclohexanes; Cyclo | 1975 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Do | 1976 |
Antitumor effect of 1,1'-polymethylene-bis (1-nitrosourea) and related compounds.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Drug Evaluation, Preclinical; | 1977 |
Human brain tumor transplantation into nude mice.
Topics: Animals; Brain Neoplasms; Carmustine; Glioblastoma; Humans; Mice; Mice, Nude; Neoplasm Transplantati | 1979 |
Development of second malignancies in rats after cure of acute leukemia L 5222 by single doses of 2-chloroethylnitrosoureas.
Topics: Animals; Carmustine; Female; Leukemia, Experimental; Male; Neoplasms, Experimental; Neoplasms, Multi | 1979 |
Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model.
Topics: Animals; Avian Sarcoma Viruses; Brain Neoplasms; Carmustine; Glioma; Neoplasms, Experimental; Rats | 1979 |
BCNU and steroids in the viral-induced dog brain tumor.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Dexamethasone; Disease Models, Animal; | 1979 |
Lymhocyte stimulatory effect of an ether-extracted preparation of Brucella abortus.
Topics: Animals; B-Lymphocytes; Brucella Vaccine; Carmustine; Lung Neoplasms; Lymphocyte Activation; Lymphoc | 1978 |
Combination chemotherapy in vitro. III. BCNU.
Topics: Antineoplastic Agents; Carmustine; Cell Survival; Drug Synergism; Humans; In Vitro Techniques; Lymph | 1979 |
Cinemicrographic determination of cell progression and division abnormalities after treatment with 1, 3 bis(2-chloroethyl)-l-nitrosourea.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Mot | 1979 |
Design and evaluation of combination chemotherapy trials in experimental animal tumor systems.
Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Colonic Neoplasms; Drug Evaluation, Preclinic | 1979 |
Influence of presensitization with allogeneic lymphoma cells on the growth and response to therapy of radiation-induced lymphomas in mice.
Topics: Animals; Carmustine; Female; Lymphoma; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental | 1979 |
Comparison of the CCNU and BCNU modification of the in vitro radiation response in 9L brain tumor cells of rats.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Dr | 1979 |
Response of a rat brain tumor to fractionated therapy with low doses of BCNU and irradiation.
Topics: Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Male; Neoplasms, Experimenta | 1979 |
BCNU and X-ray therapy of intracerebral 9L rat tumors.
Topics: Animals; Brain Neoplasms; Carmustine; Male; Neoplasms, Experimental; Pulmonary Fibrosis; Radiation I | 1979 |
Delayed cutaneous hypersensitivity to oxazolone in mice with tumors.
Topics: Animals; Carmustine; Doxorubicin; Female; Hypersensitivity, Delayed; Leukemia, Experimental; Leukemi | 1978 |
Enhancement by hyperthermia of the effect of BCNU against the EMT6 mouse tumor.
Topics: Animals; Carmustine; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neo | 1978 |
Cytocidal activity and proliferative ability of macrophages infiltrating the EMT6 tumor.
Topics: Animals; Carmustine; Cell Adhesion; Cell Division; Clone Cells; Cytotoxicity, Immunologic; Immunity; | 1978 |
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Dru | 1978 |
Preliminary observations on the effect of glucan in combination with radiation and chemotherapy in four murine tumors.
Topics: Amphotericin B; Animals; Antineoplastic Agents; Carmustine; Drug Therapy, Combination; Female; Gluca | 1978 |
Correlations between experimental chemotherapy in the murine glioma and effectiveness of clinical therapy regimens.
Topics: Animals; Carmustine; Dianhydrogalactitol; Drug Therapy, Combination; Ellipticines; Glioma; Lomustine | 1978 |
Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Female; Le | 1978 |
Tumor irradiation with intense ultrasound.
Topics: Animals; Carmustine; Cricetinae; Medulloblastoma; Neoplasms, Experimental; Soft Tissue Neoplasms; Ti | 1978 |
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Inte | 1979 |
Stimulation of ultraviolet-induced carcinogenesis by 1,3-Bis(2-chloroethyl)-1-nitrosourea.
Topics: Administration, Topical; Animals; Carcinoma, Squamous Cell; Carmustine; Female; Mice; Mice, Nude; My | 1979 |
Proliferative character and growth modes of neoplastic disease as determinants of chemotherapeutic efficacy.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Cyclophosphamide; Doxorubi | 1976 |
Combined growth-inhibitory responses and ultrastructural alterations produced by 1,3-bis(2-chloroethyl)-1-nitrosourea and dexamethasone in rat glioma cell cultures.
Topics: Carmustine; Cell Division; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Drug In | 1977 |
Brain-tumor therapy. Quantitative analysis using a model system.
Topics: Animals; Brain Neoplasms; Carmustine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug | 1977 |
cis-dichlorodiammineplatinum(II) chemotherapy in experimental murine myeloma MOPC 104E.
Topics: Animals; Carmustine; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Dru | 1977 |
Influence of tumour size on hypoxic fraction and therapeutic sensitivity of Lewis lung tumour.
Topics: Animals; Carmustine; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Radiation; Gamma R | 1977 |
Water soluble derivatives and bifunctional analogs of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
Topics: Animals; Carcinoma 256, Walker; Carmustine; Male; Mammary Neoplasms, Experimental; Neoplasms, Experi | 1977 |
In vivo clonogenic tumor cell kinetics following 1,3-bis(2-chloroethyl)-1-nitrosourea brain tumor therapy.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Division; Cell Survival; Dose-Response Relationship, Drug | 1976 |
Nitrosourea pharmacodynamics in relation to the central nervous system.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecula | 1976 |
Study of in vivo tumor state and response to therapy by analysis of DNA distribution.
Topics: Animals; Carmustine; Cell Survival; Cobalt Radioisotopes; DNA, Neoplasm; Female; Hydroxyurea; Kineti | 1976 |
Pharmacokinetic studies in the chemotherapy of neuroblastoma using the C1300 murine system.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Doxorubicin | 1976 |
Size dependence of the response of Lewis lung tumors to BCNU.
Topics: Animals; Carmustine; Cell Survival; Clone Cells; In Vitro Techniques; Lung Neoplasms; Mice; Mice, In | 1976 |
Brain tumor chemotherapy: translation of laboratory experiments into clinical trials.
Topics: Animals; Brain Neoplasms; Carmustine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Neopl | 1976 |
The response of hypoxic B16 melanoma cells to in vivo treatment with chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Cyclophosphamide; Female; In Vitro Techni | 1975 |
Evaluation of a cooperative group human myeloma protocol using the MOPC 104E myeloma model.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Line; Cell Survival; Cyclophosphamide; Disease Mode | 1975 |
In vitro evaluation of in vivo brain tumor chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Astrocytoma; Brain Neoplasms; Carmustine; Cell Survival; Clone Cells; Dose-Response Relatio | 1975 |
The effect of BCNU, CCNU and MeCCNU in the prevention of the development of tumors of the nervous system.
Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Neoplasms, Experimental; Nitrosourea Compoun | 1975 |
Changes in sensitivity to cytotoxic agents occurring during the life history of monolayer cultures of a mouse tumour cell line.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Carmustine; Cell Division; Cell Line; Cell | 1975 |
Factors influencing the survival of rat brain tumor cells after in vitro treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Dr | 1975 |
Uptake of 5-iododeoxyuridine as a measure of tumor growth and tumor inhibition.
Topics: Animals; Carmustine; Cell Transformation, Neoplastic; Cyclophosphamide; DNA, Neoplasm; Female; Idoxu | 1975 |
Pyran copolymer as an effective adjuvant to chemotherapy against a murine leukemia and solid tumor.
Topics: Adjuvants, Immunologic; Animals; Carmustine; Leukemia, Experimental; Lung Neoplasms; Mice; Mice, Inb | 1975 |
Cytotoxic effects of 1,3-bis(2 chloroethyl)-1-nitrosourea (BCNU) on cultured human glioblastomas.
Topics: Carmustine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Mitosis; Neoplasms, Experime | 1976 |
A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells.
Topics: Amphotericin B; Carmustine; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, D | 1976 |
Growth support of small B16 melanoma implants with nitrosourea-sterilized fractions of the same tumor.
Topics: Animals; Carmustine; Cell Line; Cells, Cultured; Melanoma; Mice; Neoplasm Transplantation; Neoplasms | 1976 |
Enhancement of misonidazole chemosensitization effect by mild local hyperthermia.
Topics: Animals; Carmustine; Cyclophosphamide; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Misonidazole; | 1992 |
L-histidinol: preclinical therapeutic studies in combination with antitumor agents and pharmacokinetic studies in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Cyclophosphamide; Hi | 1992 |
Effect of administration schedules on the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) by misonidazole in subcutaneous 9L tumors.
Topics: Animals; Carmustine; Drug Synergism; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experi | 1992 |
Trimodality therapy (drug/hyperthermia/radiation) with BCNU or mitomycin C.
Topics: Animals; Carmustine; Cell Line; Cesium Radioisotopes; Combined Modality Therapy; Hyperthermia, Induc | 1990 |
Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations.
Topics: Animals; Carmustine; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Neoplasm Transplant | 1990 |
Antitumor potential of low-dose chemotherapy manifested in combination with immunotherapy of Viva-Natural, a dietary seaweed extract, on Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carmustine; Doxorubicin; Immunotherapy; Lung Neoplasms; | 1990 |
Clustering of discrete cell properties essential for tumorigenicity and metastasis. II. Studies of Syrian hamster embryo fibroblasts transformed by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Carmustine; Cell Transformation, Viral; Cells, Cultured; Cricetinae; | 1989 |
Immunomodulation by various nitrosoureas and its effect on the survival of the murine host bearing a syngeneic tumor.
Topics: Animals; Carmustine; CD4-Positive T-Lymphocytes; Hypersensitivity, Delayed; Immunity, Cellular; Immu | 1989 |
Biodistribution of misonidazole and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in rats bearing unclamped and clamped 9L subcutaneous tumors.
Topics: Animals; Biological Availability; Carmustine; Constriction; Drug Interactions; Half-Life; Male; Miso | 1989 |
Effect of fluosol-DA/carbogen on etoposide/alkylating agent antitumor activity.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carbon Diox | 1988 |
Preclinical studies and clinical correlation of the effect of alkylating dose.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cell Survival; Cisp | 1988 |
Chemotherapy of mice bearing syngeneic tumors with 1,3-bis (2-chloroethyl)-1-nitrosourea is effective only in normal, but not in irradiated or nude, mice: role of L3T4+ (CD4+) and Lyt-2+ (CD8+) T cells.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Ly; Carmustine; Hypersensitivity, Delaye | 1988 |
Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Cyclophosphamide; Et | 1986 |
Carcinogenesis in F-344 rats induced by nitrosohydroxyalkyl-chloroethylureas.
Topics: Animals; Carmustine; Ethylnitrosourea; Female; Lomustine; Magnetic Resonance Spectroscopy; Male; Neo | 1986 |
Sensitization of cancer chemotherapeutic agents by nitroheterocyclics.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Survival; Drug Synergism; | 1986 |
Antitumor action of N-(2-chloroethyl)-N-nitrosocarbamoyl derivatives of biologically active polypeptide hormone fragments.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Drug Eva | 1986 |
Experimental antitumor activity against murine tumor model systems of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one (mitozolomide), a novel broad-spectrum agent.
Topics: Animals; Antineoplastic Agents; Carmustine; Drug Resistance; Mice; Mice, Inbred Strains; Neoplasms, | 1985 |
Thermochemotherapy with cis-platinum, CCNU, BCNU, chlorambucil and melphalan on murine marrow and two tumours: therapeutic gain for melphalan only.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Carmustine; Chlorambucil; Cisplatin; Combined Modality | 1985 |
New drugs on the horizon in bronchogenic carcinoma.
Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Bleomycin; Carcinoma, Bronchogenic; Carmustine; | 1972 |
The sensitivity of cells in exponential and stationary phases of growth to bleomycin and to 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Bleomycin; Carmustine; Cell Line; Cells, Cultured; Culture Techniques; DNA; Dose-Response R | 1973 |
In vitro methods to complement in vivo approaches utilizing combinations of chemotherapy and immunotherapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Bleomycin; Carmustine; Cells, Cultured; Chickens | 1974 |
Combined effect of nitrogen mustard and DNA repair inhibitor on the resistant tumor.
Topics: Animals; Carcinoma, Hepatocellular; Carmustine; Cell Line; Cyanates; DNA Repair; Drug Resistance; Dr | 1974 |
Combination chemotherapy for spontaneous AKR lymphoma.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara | 1974 |
Brief communication: Pathologic effects in rats surviving prenatal and neonatal administration of 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Animals, Newborn; Carcinogens; Carmustine; Female; Liver; Maternal-Fetal Exchange; Neoplasm | 1973 |
Influence of age of host on the chemotherapy of murine myeloma LCP-1.
Topics: Age Factors; Aging; Alkylating Agents; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; | 1974 |
Duration of inhibition of synthesis of DNA in tumors and host tissues after single doses of nitrosoureas.
Topics: Animals; Bone Marrow; Brain; Carmustine; Cricetinae; Cyclohexanes; Depression, Chemical; DNA, Neopla | 1974 |
Success and failure in the treatment of solid tumors. 3. "Cure" of metastatic Lewis lung carcinoma with methyl-CCNU (NSC-95442) and surgery-chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carmustine; Cell Line; Cyclohexanes; Cyclophosphamide; Lu | 1972 |
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso | 1972 |