carmustine has been researched along with Experimental Mammary Neoplasms in 21 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") was administered just prior to an alkylating agent, the combination treatment produced significantly more tumor cell killing across the dosage range of each alkylating agent tested compared with the alkylating agent alone." | 5.28 | Modulation of alkylating agents by etanidazole and Fluosol-DA/carbogen in the FSaIIC fibrosarcoma and EMT6 mammary carcinoma. ( Bubley, G; Coleman, CN; Eder, JP; Frei, E; Herman, TS; Holden, SA; Tanaka, J; Teicher, BA, 1991) |
| "Cyclocreatine was not very cytotoxic upon 24 h of exposure of human SW2 small-cell lung cancer cells to concentrations of up to 5 mM." | 1.29 | Cyclocreatine in cancer chemotherapy. ( Kaddurah-Daouk, R; Kufe, DW; Liu, J; Menon, K; Northey, D; Teicher, BA, 1995) |
| ") was administered just prior to an alkylating agent, the combination treatment produced significantly more tumor cell killing across the dosage range of each alkylating agent tested compared with the alkylating agent alone." | 1.28 | Modulation of alkylating agents by etanidazole and Fluosol-DA/carbogen in the FSaIIC fibrosarcoma and EMT6 mammary carcinoma. ( Bubley, G; Coleman, CN; Eder, JP; Frei, E; Herman, TS; Holden, SA; Tanaka, J; Teicher, BA, 1991) |
| " In dose-response studies low doses of the new analogs effected a higher tumor weight inhibition than BCNU in the treatment of subcutaneously implanted Walker 256." | 1.26 | Anticancer activity of new nitrosoureas against Walder carcinosarcoma 256 and DMBA-induced mammary cancer of the rat. ( Eisenbrand, G; Fiebig, HH; Zeller, WJ; Zentgraf, R, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (76.19) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fiebig, HH | 4 |
| Eisenbrand, G | 3 |
| Zeller, WJ | 2 |
| Zentgraf, R | 1 |
| Schmähl, D | 2 |
| Twentyman, PR | 3 |
| Tannock, IF | 1 |
| Teicher, BA | 3 |
| Menon, K | 1 |
| Northey, D | 2 |
| Liu, J | 1 |
| Kufe, DW | 1 |
| Kaddurah-Daouk, R | 1 |
| Holden, SA | 2 |
| Chen, YN | 1 |
| Ara, G | 1 |
| Korbut, TT | 1 |
| Ewend, MG | 1 |
| Sampath, P | 1 |
| Williams, JA | 1 |
| Tyler, BM | 1 |
| Brem, H | 1 |
| Schabel, FM | 2 |
| Lelieveld, P | 1 |
| Kallman, RF | 1 |
| Brown, JM | 1 |
| Begg, AC | 1 |
| Fu, KK | 1 |
| Vennari, J | 1 |
| Phillips, TL | 2 |
| Deutsch-Wenzel, T | 1 |
| Grau, C | 1 |
| Overgaard, J | 1 |
| Herman, TS | 1 |
| Tanaka, J | 1 |
| Eder, JP | 1 |
| Bubley, G | 1 |
| Coleman, CN | 1 |
| Frei, E | 1 |
| Dive, C | 1 |
| Workman, P | 1 |
| Watson, JV | 1 |
| Feola, JM | 1 |
| Maruyama, Y | 1 |
| Müller, N | 1 |
| Denkel, E | 1 |
| Sterzel, W | 1 |
| Wharam, MD | 1 |
| Kane, L | 1 |
| Utley, JF | 1 |
| Hahn, GM | 1 |
| Gordon, LF | 1 |
| Kurkjian, SD | 1 |
4 reviews available for carmustine and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Endocrine and cytostatic treatment of experimental mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Castration; Cyclophosp | 1980 |
Rationale for adjuvant chemotherapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cyclophosphamide; Cytarabine; Doxorubi | 1977 |
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, | 1976 |
DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds.
Topics: Alkylation; Animals; Antineoplastic Agents; Carcinogens; Carmustine; Chemical Phenomena; Chemistry; | 1986 |
17 other studies available for carmustine and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Anticancer activity of new nitrosoureas against Walder carcinosarcoma 256 and DMBA-induced mammary cancer of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Bone Marrow; Carcinoma 256, Walker | 1980 |
The response of EMT6 tumor spheroids to combined treatment with misonidazole and either nitrogen mustard, adriamycin, or BCNU.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Doxorub | 1980 |
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: cyclophosphamide and BCNU.
Topics: Animals; Body Weight; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Fibrosarcoma; Leukocy | 1980 |
Cyclocreatine in cancer chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Carmustine; Cell Division; Ce | 1995 |
CAI: effects on cytotoxic therapies in vitro and in vivo.
Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pro | 1994 |
Local delivery of chemotherapy prolongs survival in experimental brain metastases from breast carcinoma.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Camptothecin; Carboplatin; Carmustine; Combi | 1998 |
[Synergistic therapeutic effect of adriamycin with 5-fluor-uracil, with prednisolon and with cyclophosphamide on chemically induced mammary cancer of the rat (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Doxo | 1977 |
The effect of time between X-irradiation and chemotherapy on the growth of three solid mouse tumors. VI. BCNU.
Topics: Animals; Carmustine; Cell Survival; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB | 1979 |
Combination therapy of a solid murine tumor with 1, 3 bis (2-chloroethyl)-1-nitrosourea and irradiation.
Topics: Animals; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Male; Mammary Neoplasms, Exper | 1979 |
Sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea of the EMT6 tumor in vivo as determined by both tumor volume response and in vitro plating assay.
Topics: Animals; Carmustine; Cell Count; Cell Cycle; Cell Survival; Clone Cells; Lung Neoplasms; Male; Mamma | 1978 |
Water soluble derivatives and bifunctional analogs of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
Topics: Animals; Carcinoma 256, Walker; Carmustine; Male; Mammary Neoplasms, Experimental; Neoplasms, Experi | 1977 |
Effect of etoposide, carmustine, vincristine, 5-fluorouracil, or methotrexate on radiobiologically oxic and hypoxic cells in a C3H mouse mammary carcinoma in situ.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma in Situ; C | 1992 |
Modulation of alkylating agents by etanidazole and Fluosol-DA/carbogen in the FSaIIC fibrosarcoma and EMT6 mammary carcinoma.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carbon Diox | 1991 |
Inhibition of cellular esterases by the antitumour imidazotetrazines mitozolomide and temozolomide: demonstration by flow cytometry and conventional spectrofluorimetry.
Topics: Animals; Antineoplastic Agents; Carmustine; Dacarbazine; Dose-Response Relationship, Drug; Drug Scre | 1989 |
Cure rates and tumor resistance in cured mice after nitrosourea treatment of EMT6 ascites tumors.
Topics: Animals; Antineoplastic Agents; Carmustine; Drug Resistance; Female; Lethal Dose 50; Male; Mammary N | 1986 |
Response of a murine solid tumor to in vivo combined chemotherapy and irradiation.
Topics: Animals; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Do | 1973 |
Responses of cycling and noncycling cells to 1,3-bis(2-chloroethyl)-1-nitrosourea and to bleomycin.
Topics: Animals; Bleomycin; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Cricetinae; Culture T | 1974 |