carmustine has been researched along with Experimental Leukemia in 61 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response studies showed that L-histidinol conferred dose-dependent, synergistic improvements on the capacities of both BCNU and cisDDP to increase the life-span of DBA/2J mice bearing P388 leukemia." | 1.28 | L-histidinol improves the selectivity and efficacy of alkylating agents and daunomycin in mice with P388 leukaemia. ( Fang, WD; Warrington, RC, 1989) |
| " A steep dose-response relationship for the polyenes was also noted." | 1.27 | Potentiation of cytotoxicity of anticancer agents by several different polyene antibiotics. ( Dieckman, J; Medoff, G; Valeriote, F, 1984) |
| "Positive therapeutic effects of interferons (IFNs) in combination with other therapies will depend on defining modalities, doses, and timing of treatment in the setting of varied tumor burdens." | 1.27 | Schedule-dependent variations in the response of murine P388 leukemia to cyclophosphamide in combination with interferons-alpha/beta. ( Borden, EC; Bryan, GT; Hatcher, JF; Sidky, YA, 1988) |
| "Murine erythroleukemia cells (MELC) were incubated with BCNU in concentrations from 1 to 160 mu molar." | 1.27 | Interactions of 1-3 bis-(2-chloroethyl)-nitrosourea (NSC 409962) (BCNU) with clone DS19 of murine erythroleukemia cells (MELC). ( Gabelman, N, 1986) |
| "Vitamin A, whether combined with various cytotoxic drugs or not, did not show, when different experimental schedules were used, an anti-tumour effect on various murine tumours." | 1.27 | Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not. ( Bresson, ML; Cattan, A, 1986) |
| "Amphotericin B (AmB) has been shown to potentiate the cytotoxicity of several different anticancer agents in AKR mice." | 1.26 | Potentiation of anticancer agents by amphotericin B. ( Dieckman, J; Medoff, G; Valeriote, F, 1981) |
| " Piperidino-CNU and Ethylmethanesulfonato-CNU also effected cures; however, only Piperidino-CNU in one dosage effected a median survival time of greater than 90 days." | 1.26 | Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222. ( Eisenbrand, G; Fiebig, HH; Zeller, WJ, 1979) |
| "The efficacy of glucan in combination with local radiation therapy was measured using three solid murine tumors of differing abilities to induce a host defense." | 1.26 | Preliminary observations on the effect of glucan in combination with radiation and chemotherapy in four murine tumors. ( Perez, CA; Stewart, CC; Valeriote, FA, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (96.72) | 18.7374 |
| 1990's | 1 (1.64) | 18.2507 |
| 2000's | 1 (1.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crider, AM | 1 |
| Lamey, R | 1 |
| Floss, HG | 1 |
| Cassady, JM | 1 |
| Bradner, WJ | 1 |
| Karsila-Tenovuo, S | 1 |
| Jahnukainen, K | 1 |
| Peltomäki, T | 1 |
| Salmi, TT | 1 |
| Rönning, O | 1 |
| Marconi, P | 5 |
| Cassone, A | 4 |
| Baccarini, M | 3 |
| Tissi, L | 3 |
| Garaci, E | 3 |
| Bonmassar, E | 8 |
| Frati, L | 3 |
| Bistoni, F | 5 |
| Umeda, Y | 1 |
| Sakamoto, A | 1 |
| Nakamura, J | 1 |
| Ishitsuka, H | 1 |
| Yagi, Y | 1 |
| Valeriote, F | 6 |
| Medoff, G | 6 |
| Dieckman, J | 3 |
| Puccetti, P | 2 |
| Seidel, HJ | 1 |
| Kreja, L | 1 |
| Schwartz, GN | 1 |
| Biegel, JA | 1 |
| Boggs, SS | 1 |
| Delfina Pesce, C | 1 |
| Boccanera, M | 1 |
| Cenci, E | 2 |
| Maruyama, Y | 1 |
| Feola, J | 1 |
| Riccardi, C | 1 |
| Bartocci, A | 1 |
| Spreafico, F | 3 |
| Goldin, A | 9 |
| Sbaraglia, G | 1 |
| Vecchiarelli, A | 1 |
| Perito, S | 1 |
| Furusawa, E | 1 |
| Suzuki, N | 1 |
| Furusawa, S | 1 |
| Lee, JY | 1 |
| Eisenbrand, G | 3 |
| Fiebig, HH | 4 |
| Zeller, WJ | 5 |
| Schmähl, D | 3 |
| Lynch, R | 1 |
| Tolen, S | 2 |
| Murphy, SG | 1 |
| LoBuglio, AF | 1 |
| Pitzurra, M | 1 |
| Begleiter, A | 1 |
| Lam, HP | 1 |
| Goldenberg, GJ | 2 |
| Chirigos, MA | 9 |
| Schultz, RM | 1 |
| Murphy, S | 1 |
| Hemsworth, GR | 1 |
| Wolff, JS | 1 |
| Kraska, AR | 1 |
| Jensen, KE | 1 |
| Dean, JH | 1 |
| Padarathsingh, ML | 1 |
| Keys, L | 1 |
| Stewart, CC | 1 |
| Valeriote, FA | 1 |
| Perez, CA | 1 |
| Ryan, J | 1 |
| Nicolin, A | 2 |
| Cavalli, M | 1 |
| Missiroli, A | 1 |
| Zeller, WH | 1 |
| Einstein, AB | 1 |
| Fass, L | 1 |
| Fefer, A | 1 |
| Perk, K | 1 |
| Fuhrman, F | 2 |
| Pettigrew, H | 1 |
| Pryor, J | 2 |
| Ivankovic, S | 1 |
| Lynch, RG | 2 |
| Houchens, DP | 2 |
| Fioretti, MC | 1 |
| Mohr, SJ | 1 |
| Fuhrman, FS | 1 |
| Pryor, JW | 1 |
| Gaston, MR | 1 |
| Kende, M | 1 |
| Gessner, T | 1 |
| Vaughan, LA | 1 |
| Beehler, BC | 1 |
| Bartels, CJ | 1 |
| Baker, RM | 1 |
| Dorr, RT | 1 |
| Soble, MJ | 1 |
| Warrington, RC | 2 |
| Fang, WD | 2 |
| Nagarkatti, M | 1 |
| Kaplan, AM | 1 |
| Dimmock, JR | 1 |
| Jonnalagadda, SS | 1 |
| Leek, DM | 1 |
| Borden, EC | 1 |
| Sidky, YA | 1 |
| Hatcher, JF | 1 |
| Bryan, GT | 1 |
| Gabelman, N | 1 |
| Wittes, RE | 1 |
| Cattan, A | 1 |
| Bresson, ML | 1 |
| Frei, E | 1 |
| Schabel, FM | 1 |
| Pearson, GR | 1 |
| Redmon, LW | 1 |
| Pearson, JW | 6 |
| Sher, NA | 2 |
| Chaparas, SD | 4 |
| Chirigos, M | 1 |
| Pearson, J | 1 |
| Sher, N | 1 |
| Straus, MJ | 1 |
| Choi, SC | 1 |
| Schlessinger, D | 1 |
| Kobayashi, GS | 1 |
| Burchenal, JH | 1 |
| Benvenisti, D | 1 |
| Dollinger, M | 1 |
1 review available for carmustine and Experimental Leukemia
| Article | Year |
|---|---|
Unresolved issues in combination chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carmustine; Cell Cycle; Cyclo | 1986 |
60 other studies available for carmustine and Experimental Leukemia
| Article | Year |
|---|---|
Synthesis of nitrosourea derivatives of pyridine and piperidine as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Leukemia, Experimental; Leukopenia; Mice; Neoplasms, Experimental; N | 1980 |
Induced leukemia and antineoplastic agent carmustine cause permanent changes in craniofacial growth of immature rats.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Alkylating; Body Weight; Carmustine; Case-Cont | 2002 |
Relationships among tumor load, route of tumor inoculation, and response to immunochemotherapy in a murine lymphoma model.
Topics: Animals; Candida albicans; Carmustine; Cell Line; Drug Administration Schedule; Female; Immunotherap | 1983 |
Thymosin alpha 1 restores NK-cell activity and prevents tumor progression in mice immunosuppressed by cytostatics or X-rays.
Topics: Animals; Carmustine; Fluorouracil; Immunosuppression Therapy; Killer Cells, Natural; Leukemia L1210; | 1983 |
Potentiation of cytotoxicity of anticancer agents by several different polyene antibiotics.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Rela | 1984 |
The role of the peritoneal cavity in successful treatment of a murine lymphoma with chemotherapy and non-specific immunostimulation.
Topics: Adjuvants, Immunologic; Animals; Candida albicans; Carmustine; Immunotherapy; Leukemia, Experimental | 1982 |
Potentiation of anticancer agents by amphotericin B.
Topics: Amphotericin B; Animals; Antineoplastic Agents; Carmustine; Cell Survival; Colony-Forming Units Assa | 1981 |
Cellular mechanisms underlying the adjuvant activity of Candida albicans in a mouse lymphoma model.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Candida albicans; Carmustine; Cell Line; Fem | 1982 |
Hematopoietic stem cells in Friend murine leukemia virus infected mice undergoing chemotherapy: failure to eradicate Ep-independent erythropoiesis by BCNU.
Topics: Animals; Bone Marrow Cells; Carmustine; Cell Differentiation; Colony-Forming Units Assay; Erythropoi | 1982 |
A model to study drug effects on lymphoma and normal cell populations using the AKR/J mouse.
Topics: Animals; Carmustine; Cell Line; Disease Models, Animal; Germanium; Karyotyping; Leukemia, Experiment | 1982 |
[Further study of immunopotentiation in experimental antiblastic therapy by inactivated yeasts and glucan].
Topics: Adjuvants, Immunologic; Animals; Carmustine; Combined Modality Therapy; Female; Fluorouracil; Glucan | 1982 |
1,3 Bis (2-chloroethyl)-1-nitrosourea-induced host resistance to syngeneic LSA mouse leukemia.
Topics: Animals; Carmustine; Hematopoietic Stem Cells; Immunity; Leukemia, Experimental; Lymphoma; Mice; Neo | 1980 |
Combined effects of antineoplastic agents and anti-lymphoma allograft reactions.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Dacarbazine; Female; Histocompatibilit | 1980 |
[Use of BCG as an immunoadjuvant in combination with antitumor agents in virus-induced leukemia].
Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Synergism; Drug Therapy, Combination; | 1980 |
Combination chemotherapy of Rauscher leukemia and ascites tumors by narcissus alkaloid with standard drugs and effect on cellular immunity.
Topics: Alkaloids; Animals; Antineoplastic Agents; Azacitidine; Blood Cells; Carcinoma, Ehrlich Tumor; Carmu | 1975 |
Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their chemotherapeutic potential.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carmustine; Chemical Phenomena; Chemistry; Le | 1976 |
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.
Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Leukemia, Experimental; Lomustine; Male; | 1979 |
Development of second malignancies in rats after cure of acute leukemia L 5222 by single doses of 2-chloroethylnitrosoureas.
Topics: Animals; Carmustine; Female; Leukemia, Experimental; Male; Neoplasms, Experimental; Neoplasms, Multi | 1979 |
Growth and rejection of leukemia cells in individual mice after combined treatment with amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Amphotericin B; Animals; Bone Marrow; Brain Neoplasms; Carmustine; Cell Division; Clone Cells; Drug | 1978 |
L2C leukemia: a model of human acute leukemia.
Topics: Age Factors; Animals; BCG Vaccine; Carmustine; Central Nervous System Diseases; Cerebral Ventricle N | 1977 |
Combined effects of BCG or Candida albicans (CA) with antitumor agents against a virus-induced lymphoma in mice.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; BCG Vaccine; Candida albicans; Carmustine; D | 1979 |
Mechanism of uptake of nitrosoureas by L5178Y lymphoblasts in vitro.
Topics: Animals; Biological Transport; Carmustine; Cell Membrane; Cells, Cultured; Cyanates; Cytosol; Kineti | 1977 |
Animal models in cancer research which could be useful in studies of the effect of alcohol on cellular immunity.
Topics: Adrenal Cortex Hormones; Alcoholism; Animals; Carmustine; Disease Models, Animal; Humans; Immunity, | 1979 |
Chemotherapeutic activity of new 2-chloroethylnitrosoureas in rat L5222 leukemia: comparison of bifunctional and water-soluble derivatives with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Carmustine; Ethylnitrosourea; Female; Leukemia, Experimental; Male; Rats; Rats, Inbred Stra | 1978 |
L2C guinea pig leukemia. A potential model for structuring multimodality therapy.
Topics: Animals; BCG Vaccine; Carmustine; Cyclophosphamide; Disease Models, Animal; Female; Freund's Adjuvan | 1978 |
Delayed cutaneous hypersensitivity to oxazolone in mice with tumors.
Topics: Animals; Carmustine; Doxorubicin; Female; Hypersensitivity, Delayed; Leukemia, Experimental; Leukemi | 1978 |
Response of murine leukemia to combined BCNU-maleic anhydride-vinyl ether (MVE) adjuvant therapy and correlation with macrophage activation by MVE in the in vitro growth inhibition assay.
Topics: Animals; Carmustine; Cytotoxicity, Immunologic; Drug Therapy, Combination; Female; In Vitro Techniqu | 1978 |
Preliminary observations on the effect of glucan in combination with radiation and chemotherapy in four murine tumors.
Topics: Amphotericin B; Animals; Antineoplastic Agents; Carmustine; Drug Therapy, Combination; Female; Gluca | 1978 |
Response of transplanted AKR leukemia to combination therapy with amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea: dose and schedule dependency.
Topics: Amphotericin B; Animals; Carmustine; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1977 |
Immunogenicity induced in vivo by DIC in relatively non-immunogenic leukemias.
Topics: Animals; Antibody Formation; Carmustine; Dacarbazine; Leukemia; Leukemia, Experimental; Male; Mice; | 1977 |
An experimental model for meningeal leukemia in rats (L5222). Effect of treatment with BCNU and cyclophosphamide.
Topics: Animals; Brain Neoplasms; Carmustine; Cyclophosphamide; Disease Models, Animal; Drug Evaluation, Pre | 1976 |
The role of drug transport in resistance to nitrogen mustard and other alkylating agents in L518Y lymphoblsts.
Topics: Alkylating Agents; Animals; Binding, Competitive; Biological Transport; Carmustine; Cell Line; Chlor | 1975 |
Suppression of secondary cellular immunity to a tumor allograft by cyclophosphamide and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Carmustine; Cyclophosphamide; Cytotoxicity Tests, Immunologic; Graft Rejection; Immunity, C | 1975 |
Some aspects of host response to levamisole after chemotherapy in a murine leukemia.
Topics: Animals; Carmustine; Immunity, Cellular; Leukemia, Experimental; Levamisole; Male; Mice; Mice, Inbre | 1975 |
Prolongation of chemotherapeutically induced remission of a syneneic murine leukemia by L-2,3,5,6-tetrahydro-6-phenylimidazo[2.1-BETA]thiazole hydrochloride.
Topics: Adjuvants, Immunologic; Animals; Carmustine; Graft Rejection; Immunosuppressive Agents; Leukemia, Ex | 1975 |
Chemotherapy of the transplantable acute leukemia L5222 in rats.
Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Carmustine; Cell Division; Cyclophospha | 1975 |
A murine model for central nervous system leukemia and its possible relevance to human leukemia.
Topics: Amphotericin B; Animals; Brain; Carmustine; Central Nervous System Diseases; Disease Models, Animal; | 1975 |
Uptake of 5-iododeoxyuridine as a measure of tumor growth and tumor inhibition.
Topics: Animals; Carmustine; Cell Transformation, Neoplastic; Cyclophosphamide; DNA, Neoplasm; Female; Idoxu | 1975 |
Pyran copolymer as an effective adjuvant to chemotherapy against a murine leukemia and solid tumor.
Topics: Adjuvants, Immunologic; Animals; Carmustine; Leukemia, Experimental; Lung Neoplasms; Mice; Mice, Inb | 1975 |
Antigenic changes of L5178Y lymphoma after treatment with 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide in vivo.
Topics: Animals; Antigens, Neoplasm; Carmustine; Immunization; Immunization, Passive; Immunosuppression Ther | 1976 |
Drug-mediated immunogenic changes of virus-induced leukemia in vivo.
Topics: Animals; Antigens, Neoplasm; Carmustine; Cell Line; Cross Reactions; Cyclophosphamide; Dacarbazine; | 1976 |
Elevated pentose cycle and glucuronyltransferase in daunorubicin-resistant P388 cells.
Topics: Animals; Carbon Dioxide; Carmustine; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance; Gluc | 1990 |
H2-antagonists and carmustine.
Topics: Animals; Bone Marrow; Carmustine; Cimetidine; Drug Synergism; Histamine H2 Antagonists; Leukemia P38 | 1989 |
L-histidinol improves the selectivity and efficacy of alkylating agents and daunomycin in mice with P388 leukaemia.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; C | 1989 |
The role of suppressor T cells in BCNU-mediated rejection of a syngeneic tumor.
Topics: Animals; Carmustine; Cytotoxicity, Immunologic; Female; Graft Rejection; Immunity, Innate; Immunizat | 1985 |
Evaluation of Mannich bases of styryl ketones and related hydrazones for activity against P388 leukemia.
Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Hydrazones; Ketones; Leukemia P388; Leuke | 1988 |
Schedule-dependent variations in the response of murine P388 leukemia to cyclophosphamide in combination with interferons-alpha/beta.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Drug Administ | 1988 |
Interactions of 1-3 bis-(2-chloroethyl)-nitrosourea (NSC 409962) (BCNU) with clone DS19 of murine erythroleukemia cells (MELC).
Topics: Animals; Carmustine; Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Dimethyl Sulfoxide; | 1986 |
Vitamin A: failure to demonstrate in mice an anti-tumour effect, whether combined with cytotoxic drugs or not.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Cyclophosphamide; Et | 1986 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara | 1974 |
Serochemotherapy against a Moloney virus-induced leukemia.
Topics: Animals; Antibodies, Neoplasm; Antibodies, Viral; Carmustine; Fluorescent Antibody Technique; Immuni | 1973 |
Effect of three strains of BCG against a murine leukemia after drug therapy.
Topics: Animals; Antigens, Bacterial; BCG Vaccine; Carmustine; Leukemia, Experimental; Leukemia, Lymphoid; M | 1973 |
Combined drug and immunostimulation therapy against a syngeneic murine leukemia.
Topics: Animals; BCG Vaccine; Carmustine; Corynebacterium; Diethylamines; Evaluation Studies as Topic; Fluor | 1974 |
BCG immunization for the lymphoid leukemia line (LSTRA) in CDF1 mice.
Topics: Animals; BCG Vaccine; Carmustine; Cell Line; Dose-Response Relationship, Drug; Leukemia, Experimenta | 1973 |
Effect of dose and route of Bacillus Calmette-Guérin in chemoimmunostimulation therapy of a murine leukemia.
Topics: Animals; BCG Vaccine; Carmustine; Leukemia, Experimental; Male; Mice; Moloney murine leukemia virus; | 1973 |
Increased life-span in AKR leukemia mice treated with prophylactic chemotherapy.
Topics: Animals; Carmustine; Cyclophosphamide; Evaluation Studies as Topic; Leukemia, Experimental; Methotre | 1973 |
Brief communication: Cure of murine leukemia with drug and interferon treatment.
Topics: Animals; Carmustine; Interferons; Leukemia, Experimental; Male; Mice; Remission, Spontaneous | 1973 |
Augmentation of chemotherapeutically induced remission of a murine leukemia by a chemical immunoadjuvant.
Topics: Adjuvants, Immunologic; Animals; Carmustine; Graft Rejection; Leukemia, Experimental; Leukemia, Lymp | 1973 |
Synergistic effect of amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea against a transplantable AKR leukemia.
Topics: Amphotericin B; Animals; Bone Marrow Cells; Brain Neoplasms; Carmustine; Cell Survival; Clone Cells; | 1974 |
Experimental studies with L-asparaginase in mouse leukemias.
Topics: Animals; Antibiotics, Antineoplastic; Asparaginase; Asparagine; Carmustine; Cell Line; Child, Presch | 1970 |