Page last updated: 2024-10-24

carmustine and Delayed Effects, Prenatal Exposure

carmustine has been researched along with Delayed Effects, Prenatal Exposure in 6 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Research Excerpts

ExcerptRelevanceReference
"The experimental model of cortical dysplasia (CD) obtained by administering carmustine (1-3-bis-chloroethyl-nitrosurea [BCNU]) in pregnant rat uterus mimics the histopathological abnormalities observed in human CD patients: altered cortical layering, and presence of heterotopia and dysmorphic/heterotopic neurons."1.35Expression of layer-specific markers in the adult neocortex of BCNU-Treated rat, a model of cortical dysplasia. ( Frassoni, C; Inverardi, F; Moroni, RF; Regondi, MC; Spreafico, R; Watakabe, A; Yamamori, T, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pennacchio, P1
Noé, F1
Gnatkovsky, V1
Moroni, RF2
Zucca, I1
Regondi, MC2
Inverardi, F2
de Curtis, M1
Frassoni, C2
Watakabe, A1
Yamamori, T1
Spreafico, R1
Ducray, F1
Colin, P1
Cartalat-Carel, S1
Pelissou-Guyotat, I1
Mahla, K1
Audra, P1
Gaucherand, P1
Honnorat, J1
Trouillas, P1
Uyanikgil, Y1
Baka, M1
Ateş, U1
Turgut, M1
Yavaşoğlu, A1
Ulker, S1
Sözmen, EY1
Sezer, E1
Elmas, C1
Yurtseven, ME1
Long, LL1
Xiao, B1
Song, YM1
Wang, K1
Szczech, J1
Godlewski, A1

Other Studies

6 other studies available for carmustine and Delayed Effects, Prenatal Exposure

ArticleYear
Increased pCREB expression and the spontaneous epileptiform activity in a BCNU-treated rat model of cortical dysplasia.
    Epilepsia, 2015, Volume: 56, Issue:9

    Topics: Age Factors; Animals; Antineoplastic Agents, Alkylating; Brain; Calbindins; Carmustine; CREB-Binding

2015
Expression of layer-specific markers in the adult neocortex of BCNU-Treated rat, a model of cortical dysplasia.
    Neuroscience, 2009, Mar-17, Volume: 159, Issue:2

    Topics: Animals; Carmustine; Disease Models, Animal; DNA-Binding Proteins; Female; Gene Expression Regulatio

2009
[Management of malignant gliomas diagnosed during pregnancy].
    Revue neurologique, 2006, Volume: 162, Issue:3

    Topics: Abortion, Therapeutic; Adrenal Cortex Hormones; Adult; Algorithms; Anesthesia, General; Antineoplast

2006
Neuroprotective effects of melatonin upon the offspring cerebellar cortex in the rat model of BCNU-induced cortical dysplasia.
    Brain research, 2007, Jul-30, Volume: 1160

    Topics: Animals; Animals, Newborn; Brain Diseases; Bromodeoxyuridine; Carmustine; Cerebellar Cortex; Disease

2007
[Changes of expression of cation-chloride cotransporter genes in hippocampus of cortical dysplasia: experiment with rat].
    Zhonghua yi xue za zhi, 2007, May-22, Volume: 87, Issue:19

    Topics: Animals; Animals, Newborn; Carmustine; Chlorides; Female; Gene Expression; Hippocampus; Ion Transpor

2007
Effect of BCNU given to pregnant female rats on neuroglia morphology and histochemistry in the progeny.
    Neuropatologia polska, 1985, Volume: 23, Issue:4

    Topics: Age Factors; Animals; Brain; Carmustine; Enzyme Activation; Female; Karyometry; Neuroglia; Pregnancy

1985