carmustine has been researched along with Complication, Postoperative in 22 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For newly diagnosed glioblastomas treated with resection in association with the standard combined chemoradiotherapy, the impact of Carmustine wafer implantation remains debated regarding postoperative infections, quality of life, and feasibility of adjuvant oncological treatments." | 7.85 | Extent of resection and Carmustine wafer implantation safely improve survival in patients with a newly diagnosed glioblastoma: a single center experience of the current practice. ( Abi Lahoud, G; Bou Nassif, R; Chretien, F; Devaux, B; Dezamis, E; Dhermain, F; Dumont, S; Lechapt-Zalcmann, E; Louvel, G; Oppenheim, C; Pallud, J; Parraga, E; Peeters, S; Roux, A; Sauvageon, X; Zanello, M, 2017) |
| "Study the feasibility and effectiveness of a treatment associated surgery, intraoperative chemotherapy (carmustine wafers), and concomitant radiochemotherapy (temozolomide) for the management of newly diagnosed, high-grade gliomas." | 7.79 | Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases. ( Colin, P; Debreuve, A; Duntze, J; Eap, C; Emery, E; Guillamo, JS; Jovenin, N; Lechapt-Zalcman, E; Litré, CF; Menei, P; Metellus, P; Peruzzi, P; Rousseaux, P; Théret, E, 2013) |
| " In this study, we have assessed the role of MDT in implementing the TA121 appraisal of the use of carmustine wafers in high grade gliomas." | 7.78 | NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice. ( Ashkan, K; Cruickshank, G; Grundy, P; Price, SJ; Whittle, IR, 2012) |
| "With the eventual goal of reducing relapse and thus improving overall survival in selected lymphoma patients, a Phase I study was performed using the cytoprotectant amifostine to permit safe dose-augmentation of melphalan in the carmustine (BCNU), etoposide, cytarabine (arabinosylcytosine), and melphalan (BEAM) regimen before autologous hematopoietic stem cell transplantation." | 5.15 | A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection. ( Abboud, CN; Becker, MW; Bernstein, SH; Constine, LS; Friedberg, JW; Ifthikharuddin, JJ; Liesveld, JL; Loughner, JE; Milner, LA; Phillips, GL; Vesole, DH, 2011) |
| "Anticonvulsant therapy is usually recommended before surgery in all patients affected by high grade glioma who are planned to be treated with Carmustine 1,3-bis [2 chloroetyl]-1-nitrosurea, or BCNU) wafers." | 5.15 | Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience. ( Ciccarino, P; d'Avella, D; Del Moro, G; Della Puppa, A; Denaro, L; Lombardi, G; Manara, R; Rossetto, M; Rotilio, A; Scienza, R, 2011) |
| "In patients with glioblastoma multiforme (GBM), there is no consensus on the sequential use of two existing regimens: post-operative Gliadel implantation into the surgical cavity and concomitant temozolomide with radiotherapy followed by adjuvant temozolomide ('Stupp protocol')." | 4.87 | The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review. ( Achawal, S; Dixit, S; Hingorani, M; Scott, I, 2011) |
| "For newly diagnosed glioblastomas treated with resection in association with the standard combined chemoradiotherapy, the impact of Carmustine wafer implantation remains debated regarding postoperative infections, quality of life, and feasibility of adjuvant oncological treatments." | 3.85 | Extent of resection and Carmustine wafer implantation safely improve survival in patients with a newly diagnosed glioblastoma: a single center experience of the current practice. ( Abi Lahoud, G; Bou Nassif, R; Chretien, F; Devaux, B; Dezamis, E; Dhermain, F; Dumont, S; Lechapt-Zalcmann, E; Louvel, G; Oppenheim, C; Pallud, J; Parraga, E; Peeters, S; Roux, A; Sauvageon, X; Zanello, M, 2017) |
| "Patients with glioblastoma treated with BCNU wafer implantation for recurrence frequently receive frontline chemoradiotherapy with temozolomide as part of the Stupp protocol." | 3.80 | Evaluation of post-operative complications associated with repeat resection and BCNU wafer implantation in recurrent glioblastoma. ( Ewelt, C; Hänggi, D; Isik, G; Sabel, M; Samis Zella, MA; Schroeteler, J; Slotty, PJ; Steiger, HJ; Wallocha, M, 2014) |
| "Study the feasibility and effectiveness of a treatment associated surgery, intraoperative chemotherapy (carmustine wafers), and concomitant radiochemotherapy (temozolomide) for the management of newly diagnosed, high-grade gliomas." | 3.79 | Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases. ( Colin, P; Debreuve, A; Duntze, J; Eap, C; Emery, E; Guillamo, JS; Jovenin, N; Lechapt-Zalcman, E; Litré, CF; Menei, P; Metellus, P; Peruzzi, P; Rousseaux, P; Théret, E, 2013) |
| " In this study, we have assessed the role of MDT in implementing the TA121 appraisal of the use of carmustine wafers in high grade gliomas." | 3.78 | NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice. ( Ashkan, K; Cruickshank, G; Grundy, P; Price, SJ; Whittle, IR, 2012) |
| " We report the case of a 57-year-old man who had parietal glioblastoma resection with local carmustine chemotherapy and who presented a clostridial brain abscess three weeks later." | 3.75 | [Clostridial brain abscess after glioblastoma resection: case report and critical review of the literature]. ( Bajolet, O; Duntze, J; Eap, C; Litré, CF; Peruzzi, P; Rousseaux, P; Theret, E, 2009) |
| " Interstitial chemotherapy with BCNU-polymer with subsequent radiation therapy appears to be safe as an initial therapy." | 2.68 | The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial. ( Brem, H; Burger, PC; Ewend, MG; Greenhoot, J; Piantadosi, S; Sisti, M, 1995) |
| "Thirty-one patients with resistant Hodgkin's disease were treated by an identical high dose chemotherapy regimen and autologous bone marrow transplantation." | 2.66 | GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease. ( Devereaux, S; Goldstone, AH; Gribben, JG; Linch, DC; McMillan, A; Patterson, K, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Roux, A | 2 |
| Aboubakr, O | 1 |
| Elia, A | 1 |
| Moiraghi, A | 1 |
| Benevello, C | 1 |
| Fathallah, H | 1 |
| Parraga, E | 2 |
| Oppenheim, C | 2 |
| Chretien, F | 2 |
| Dezamis, E | 2 |
| Zanello, M | 2 |
| Pallud, J | 2 |
| Illic, R | 1 |
| Somma, T | 1 |
| Savic, D | 1 |
| Frio, F | 1 |
| Milicevic, M | 1 |
| Solari, D | 1 |
| Nikitovic, M | 1 |
| Lavrnic, S | 1 |
| Raicevic, S | 1 |
| Milosevic, S | 1 |
| Cavallo, LM | 1 |
| Cappabianca, P | 1 |
| Grujicic, D | 1 |
| Peeters, S | 1 |
| Bou Nassif, R | 1 |
| Abi Lahoud, G | 1 |
| Lechapt-Zalcmann, E | 1 |
| Dhermain, F | 1 |
| Dumont, S | 1 |
| Louvel, G | 1 |
| Sauvageon, X | 1 |
| Devaux, B | 1 |
| Samis Zella, MA | 1 |
| Wallocha, M | 1 |
| Slotty, PJ | 1 |
| Isik, G | 1 |
| Hänggi, D | 1 |
| Schroeteler, J | 1 |
| Ewelt, C | 1 |
| Steiger, HJ | 1 |
| Sabel, M | 1 |
| Duntze, J | 2 |
| Litré, CF | 2 |
| Bajolet, O | 1 |
| Theret, E | 2 |
| Eap, C | 2 |
| Peruzzi, P | 2 |
| Rousseaux, P | 2 |
| Precupanu, CM | 1 |
| Girodet, J | 1 |
| Mariani, P | 1 |
| Zanni, M | 1 |
| Mathiot, C | 1 |
| Escande, MC | 1 |
| Brault, P | 1 |
| Decaudin, D | 1 |
| Lane, N | 1 |
| Donaldson, MR | 1 |
| Stetson, CL | 1 |
| Smith, JL | 1 |
| Phillips, GL | 1 |
| Bernstein, SH | 1 |
| Liesveld, JL | 1 |
| Abboud, CN | 1 |
| Becker, MW | 1 |
| Constine, LS | 1 |
| Ifthikharuddin, JJ | 1 |
| Loughner, JE | 1 |
| Milner, LA | 1 |
| Vesole, DH | 1 |
| Friedberg, JW | 1 |
| Bock, HC | 1 |
| Cohnen, J | 1 |
| Keric, N | 1 |
| Kantelhardt, SR | 1 |
| Giese, A | 1 |
| Dixit, S | 1 |
| Hingorani, M | 1 |
| Achawal, S | 1 |
| Scott, I | 1 |
| Della Puppa, A | 1 |
| Denaro, L | 1 |
| Rossetto, M | 1 |
| Ciccarino, P | 1 |
| Manara, R | 1 |
| Lombardi, G | 1 |
| Del Moro, G | 1 |
| Rotilio, A | 1 |
| d'Avella, D | 1 |
| Scienza, R | 1 |
| Price, SJ | 1 |
| Whittle, IR | 1 |
| Ashkan, K | 1 |
| Grundy, P | 1 |
| Cruickshank, G | 1 |
| Debreuve, A | 1 |
| Jovenin, N | 1 |
| Lechapt-Zalcman, E | 1 |
| Metellus, P | 1 |
| Colin, P | 1 |
| Guillamo, JS | 1 |
| Emery, E | 1 |
| Menei, P | 1 |
| Rao, PS | 1 |
| Kuittinen, T | 1 |
| Jantunen, E | 1 |
| Vanninen, E | 1 |
| Mussalo, H | 1 |
| Vuolteenaho, O | 1 |
| Ala-Kopsala, M | 1 |
| Nousiainen, T | 1 |
| Hartikainen, J | 1 |
| Williams, KM | 1 |
| Higman, MA | 1 |
| Chen, AR | 1 |
| Schwartz, CL | 1 |
| Wharam, M | 1 |
| Colombani, P | 1 |
| Arceci, RJ | 1 |
| Siddiqi, TS | 1 |
| Buchheit, WA | 1 |
| Brem, H | 1 |
| Ewend, MG | 1 |
| Piantadosi, S | 1 |
| Greenhoot, J | 1 |
| Burger, PC | 1 |
| Sisti, M | 1 |
| McGirt, MJ | 1 |
| Villavicencio, AT | 1 |
| Bulsara, KR | 1 |
| Friedman, HS | 1 |
| Friedman, AH | 1 |
| Ransohoff, J | 1 |
| Lieberman, A | 1 |
| Devereaux, S | 1 |
| Linch, DC | 1 |
| Gribben, JG | 1 |
| McMillan, A | 1 |
| Patterson, K | 1 |
| Goldstone, AH | 1 |
| Meloni, G | 1 |
| De Fabritiis, P | 1 |
| Petti, MC | 1 |
| Pulsoni, A | 1 |
| Sandrelli, A | 1 |
| Covelli, A | 1 |
| Simone, F | 1 |
| Mandelli, F | 1 |
1 review available for carmustine and Complication, Postoperative
| Article | Year |
|---|---|
The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car | 2011 |
4 trials available for carmustine and Complication, Postoperative
| Article | Year |
|---|---|
A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Carmus | 2011 |
Postoperative seizure in high grade glioma patients treated with BCNU wafers. A mono-institutional experience.
Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Clinical Trials, Ph | 2011 |
The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain N | 1995 |
GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmus | 1989 |
17 other studies available for carmustine and Complication, Postoperative
| Article | Year |
|---|---|
Carmustine wafer implantation for supratentorial glioblastomas, IDH-wildtype in "extreme" neurosurgical conditions.
Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cohort Studies; C | 2023 |
A Survival Analysis with Identification of Prognostic Factors in a Series of 110 Patients with Newly Diagnosed Glioblastoma Before and After Introduction of the Stupp Regimen: A Single-Center Observational Study.
Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Craniot | 2017 |
Extent of resection and Carmustine wafer implantation safely improve survival in patients with a newly diagnosed glioblastoma: a single center experience of the current practice.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Carmustine; Combined Modality The | 2017 |
Evaluation of post-operative complications associated with repeat resection and BCNU wafer implantation in recurrent glioblastoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb | 2014 |
[Clostridial brain abscess after glioblastoma resection: case report and critical review of the literature].
Topics: Antineoplastic Agents, Alkylating; Brain Abscess; Brain Neoplasms; Carmustine; Clostridium Infection | 2009 |
Pseudo-bowel obstruction due to varicella zoster virus infection after autologous stem cell transplantation.
Topics: Acyclovir; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined C | 2009 |
JAAD grand rounds quiz*: Dusky intertriginous plaques and acral erythema after bone marrow transplant.
Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Carmustine; Cyclophosphamide; Erythema; E | 2010 |
Occlusion of surgical opening of the ventricular system with fibrinogen-coated collagen fleece: a case collection study.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Cerebral V | 2011 |
NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.
Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Therapy; Fem | 2012 |
Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: prospective, observational, multicenter study on 92 cases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemoradiotherapy, Adjuvant; Dacarbazine | 2013 |
Nephrotic syndrome in patients with peripheral blood stem cell transplant.
Topics: Acute Kidney Injury; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineop | 2005 |
Cardiac effects within 3 months of BEAC high-dose therapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Atrial Natriuretic Factor; Biomarkers; | 2006 |
Successful treatment of a child with late-onset T-cell post-transplant lymphoproliferative disorder/lymphoma.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antine | 2008 |
Disseminated intravascular coagulation--a complication of 1,3-bis(2-chlorethyl)-nitrosourea therapy.
Topics: Adult; Astrocytoma; Brain Neoplasms; Carmustine; Disseminated Intravascular Coagulation; Female; Hum | 1983 |
Management of tumor bed cysts after chemotherapeutic wafer implantation. Report of four cases.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Biopsy; Brain | 2002 |
Surgical therapy of primary malignant brain tumors.
Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Male; Mid | 1978 |
Autologous bone marrow transplantation for patients with acute myelogenous leukemia in complete remission.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; | 1987 |