carmustine has been researched along with Colorectal Cancer in 13 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to determine if hepatic arterial therapy with floxuridine (F), mitomycin, and carmustine (BCNU) (FMB) is superior to hepatic arterial therapy with F alone in previously treated patients with hepatic metastases from colorectal cancer." | 9.07 | Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer. ( Botet, J; Budd, A; Cohen, A; Conti, JA; Kemeny, N; Niedzwiecki, D; Seiter, K; Sigurdson, ER; Tao, Y, 1993) |
| "Seventy-five previously untreated patients with measurable advanced colorectal cancer were treated with 5 fluorouracil 1,000 mg/m2 as a 24-hour intravenous (i." | 8.78 | 120-hour 5-fluorouracil (5-FU) continuous infusion (CI) plus BCNU in advanced colorectal cancer. ( Aguilo, J; Asencio, F; Candel, MT; Delgado, F; García-Reinoso, J; Martínez-Abad, M; Sánchez, JJ; Sanchis, C; Viciano, V; Villar-Grimalt, A, 1991) |
| "This study was designed to determine if hepatic arterial therapy with floxuridine (F), mitomycin, and carmustine (BCNU) (FMB) is superior to hepatic arterial therapy with F alone in previously treated patients with hepatic metastases from colorectal cancer." | 5.07 | Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer. ( Botet, J; Budd, A; Cohen, A; Conti, JA; Kemeny, N; Niedzwiecki, D; Seiter, K; Sigurdson, ER; Tao, Y, 1993) |
| "Seventy-five previously untreated patients with measurable advanced colorectal cancer were treated with 5 fluorouracil 1,000 mg/m2 as a 24-hour intravenous (i." | 4.78 | 120-hour 5-fluorouracil (5-FU) continuous infusion (CI) plus BCNU in advanced colorectal cancer. ( Aguilo, J; Asencio, F; Candel, MT; Delgado, F; García-Reinoso, J; Martínez-Abad, M; Sánchez, JJ; Sanchis, C; Viciano, V; Villar-Grimalt, A, 1991) |
| "Sequential biopsies of metastases before and after streptozotocin were conducted to determine whether streptozotocin depletes tumor AT." | 2.68 | Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers. ( Gerson, SL; Gordon, NH; Haaga, JR; Stellato, TA; Trey, JE; Willson, JK, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janciauskiene, R | 1 |
| Juozaityte, E | 1 |
| Pavalkis, D | 1 |
| Schmitz, R | 4 |
| Krakamp, B | 3 |
| Troidl, H | 1 |
| Wong, RP | 1 |
| Baetz, T | 1 |
| Krahn, MJ | 1 |
| Biagi, J | 1 |
| Wainman, N | 1 |
| Eisenhauer, E | 1 |
| Willson, JK | 1 |
| Haaga, JR | 1 |
| Trey, JE | 1 |
| Stellato, TA | 1 |
| Gordon, NH | 1 |
| Gerson, SL | 1 |
| Falkson, CI | 1 |
| Falkson, G | 1 |
| Falkson, HC | 1 |
| Uys, A | 1 |
| Keren-Rosenberg, S | 1 |
| Kemeny, N | 1 |
| Cohen, A | 1 |
| Seiter, K | 1 |
| Conti, JA | 1 |
| Sigurdson, ER | 1 |
| Tao, Y | 1 |
| Niedzwiecki, D | 1 |
| Botet, J | 1 |
| Budd, A | 1 |
| Ismail Ali, A | 1 |
| Simadibrata, R | 1 |
| Aziz Rani, A | 1 |
| Chudahman, M | 1 |
| Dharmika, D | 1 |
| Villar-Grimalt, A | 1 |
| Candel, MT | 1 |
| Delgado, F | 1 |
| García-Reinoso, J | 1 |
| Sanchis, C | 1 |
| Viciano, V | 1 |
| Asencio, F | 1 |
| Martínez-Abad, M | 1 |
| Aguilo, J | 1 |
| Sánchez, JJ | 1 |
| Knöpfle, G | 1 |
| Leidig, P | 1 |
| Heim, ME | 1 |
| Mennigen, R | 2 |
| Barkun, J | 1 |
| Klauke, H | 1 |
| Köhler, L | 1 |
| Fuchshuber, P | 1 |
| Eypasch, E | 1 |
| Ficorella, C | 1 |
| Cagnazzo, P | 1 |
| Cardi, G | 1 |
| Ricciuti, FP | 1 |
| Marchetti, P | 1 |
| Frati, L | 1 |
| Marchei, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study of Second-Line SarCNU (NSC 364432) in Patients With Recurrent/Metastatic Colorectal Cancer[NCT00028015] | Phase 2 | 18 participants (Actual) | Interventional | 2001-10-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for carmustine and Colorectal Cancer
| Article | Year |
|---|---|
[The role of the regional (intra-arterial) chemotherapy in the treatment of hepatic metastases of colorectal cancer].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 2003 |
120-hour 5-fluorouracil (5-FU) continuous infusion (CI) plus BCNU in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Colorectal Neopl | 1991 |
5 trials available for carmustine and Colorectal Cancer
| Article | Year |
|---|---|
SarCNU in recurrent or metastatic colorectal cancer: a phase II study of the National Cancer Institute of Canada Clinical Trials Group.
Topics: Adult; Aged; Antineoplastic Agents; Canada; Carmustine; Colorectal Neoplasms; Dose-Response Relation | 2006 |
Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers.
Topics: Adult; Aged; Carmustine; Colorectal Neoplasms; DNA Repair; Drug Resistance; Drug Therapy, Combinatio | 1995 |
FIVB plus GM-CSF in metastatic colorectal cancer.
Topics: Adult; Aged; Carmustine; Colorectal Neoplasms; Diarrhea; Drug Evaluation; Drug Interactions; Female; | 1994 |
Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorect | 1993 |
Value of in vivo tissue testing in predicting the clinical response to regional perfusion chemotherapy in colorectal cancer patients with liver metastases.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorect | 1989 |
6 other studies available for carmustine and Colorectal Cancer
| Article | Year |
|---|---|
Perfusion chemotherapy for colorectal liver metastases: a randomized study comparing FUDR against 5-FU/BCNU.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorectal Neoplasms; Floxuridine; Fluor | 1989 |
Chemotherapy for colorectal carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chemotherapy, Adjuvant; Colorectal Neopl | 1992 |
[Primary and metastatic liver tumors--evaluation of tumor regression and response with regional cytostatic drug therapy by sonography and fine needle puncture histology].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Hepatocellular; Carmustin | 1990 |
[Intra-arterial chemotherapy of local recurrences of gastrointestinal tumors].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorectal Neopla | 1989 |
Treatment with 5-FU, VCR and BCNU in tumor bearing nude mice.
Topics: Adenocarcinoma; Animals; Carmustine; Colorectal Neoplasms; Female; Fluorouracil; Humans; Mice; Mice, | 1989 |
[Rationale and current results of loco-regional chemotherapy in hepatic metastases of colorectal carcinoma].
Topics: Antineoplastic Agents; Carmustine; Cisplatin; Colorectal Neoplasms; Doxorubicin; Floxuridine; Fluoro | 1987 |