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carmustine and Cell Transformation, Neoplastic

carmustine has been researched along with Cell Transformation, Neoplastic in 16 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riolobos, L1
Gad, EA1
Treuting, PM1
Timms, AE1
Hershberg, EA1
Corulli, LR1
Rodmaker, E1
Disis, ML1
Ghosh, M1
Dwyer-Nield, LD1
Kwon, JB1
Barthel, L1
Janssen, WJ1
Merrick, DT1
Keith, RL1
Darby Weydert, CJ1
Smith, BB1
Xu, L1
Kregel, KC1
Ritchie, JM1
Davis, CS1
Oberley, LW1
Milojković, D1
Aldouri, M1
Pagliuca, A1
Mufti, GJ1
Devereux, S1
Salmon, SE3
Erickson, LC3
Zlotogorski, C1
Drago, JR1
Worgul, TJ1
Gallagher, C1
Hofmann, V1
Durie, BG2
Bradley, MO2
Kohn, KW2
Hamburger, AW1
Bonmassar, E1
Houchens, DP1
Fioretti, MC1
Goldin, A1
von Hofe, E1
Kennedy, AR1
Thomale, J1
Huh, NH1
Nehls, P1
Eberle, G1
Rajewsky, MF1
Komatsu, K1
Miller, RC1
Hall, EJ1
Holland, JF1
Glidewell, O1

Trials

1 trial available for carmustine and Cell Transformation, Neoplastic

ArticleYear
Chemotherapy of acute lymphocytic leukemia of childhood.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Carmustine; Cell Division; Cell Transformati

1972

Other Studies

15 other studies available for carmustine and Cell Transformation, Neoplastic

ArticleYear
The Effect of Mouse Strain, Sex, and Carcinogen Dose on Toxicity and the Development of Lung Dysplasia and Squamous Cell Carcinomas in Mice.
    Cancer prevention research (Philadelphia, Pa.), 2019, Volume: 12, Issue:8

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Carmustine; Cell Transformation, Neoplastic; Dose-Re

2019
Tracheal dysplasia precedes bronchial dysplasia in mouse model of N-nitroso trischloroethylurea induced squamous cell lung cancer.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinoma, Squamous Cell; Carmustine; Cell Transformation, Neop

2015
Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment.
    Free radical biology & medicine, 2003, Feb-01, Volume: 34, Issue:3

    Topics: Adenoviridae; Animals; Antioxidants; Carmustine; Catalase; Cattle; Cell Division; Cell Transformatio

2003
Prolonged remission in a case of Richter's transformation of B-cell chronic lymphocytic leukaemia following adoptive immunotherapy.
    Bone marrow transplantation, 2006, Volume: 38, Issue:6

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Muri

2006
In vitro cloning and chemosensitivity of human myeloma stem cells.
    Clinics in haematology, 1982, Volume: 11, Issue:1

    Topics: Animals; Carmustine; Cell Transformation, Neoplastic; Clone Cells; Colony-Forming Units Assay; DNA;

1982
Induction and repair of macromolecular damage by alkylating agents.
    Cancer treatment reviews, 1984, Volume: 11 Suppl A

    Topics: Animals; Carmustine; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Colony-

1984
Castration--chemotherapy treatment of prostate cancer model.
    The Journal of surgical research, 1981, Volume: 30, Issue:4

    Topics: Animals; Carmustine; Castration; Cell Transformation, Neoplastic; Cisplatin; Cyclophosphamide; Disea

1981
Drug resistance in multiple myeloma associated with high in vitro incorporation of 3H-thymidine.
    Blood, 1981, Volume: 58, Issue:3

    Topics: Carmustine; Cell Nucleus; Cell Transformation, Neoplastic; Doxorubicin; Drug Resistance; Drug Therap

1981
Strand breaks in DNA from normal and transformed human cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1977, Volume: 37, Issue:10

    Topics: Alkalies; Carmustine; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Grad

1977
Differential inhibition of the rejoining of X-ray-induced DNA strand breaks in normal and transformed human fibroblasts treated with 1,3-bis(2-chloroethyl)-1-nitrosourea in vitro.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Carmustine; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; DNA, Neopla

1978
A new basis for treatment of multiple myeloma.
    Schweizerische medizinische Wochenschrift, 1978, Oct-14, Volume: 108, Issue:41

    Topics: Carmustine; Cell Transformation, Neoplastic; Doxorubicin; Drug Resistance; Humans; Melphalan; Multip

1978
Uptake of 5-iododeoxyuridine as a measure of tumor growth and tumor inhibition.
    Chemotherapy, 1975, Volume: 21, Issue:6

    Topics: Animals; Carmustine; Cell Transformation, Neoplastic; Cyclophosphamide; DNA, Neoplasm; Female; Idoxu

1975
X-ray induction of O6-alkylguanine-DNA alkyltransferase protects against some of the biological effects of N-methyl-N'-nitro-N-nitrosoguanidine in C3H 10T1/2 cells.
    Radiation research, 1991, Volume: 127, Issue:2

    Topics: Animals; Carmustine; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; En

1991
Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:24

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; DNA; DN

1990
The oncogenic potential of a combination of hyperthermia and chemotherapy agents.
    British journal of cancer, 1988, Volume: 57, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Cell Transformation, Neoplastic; Dactinomycin; Dose-Response Rel

1988