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carmustine and Carcinoma, Lewis Lung

carmustine has been researched along with Carcinoma, Lewis Lung in 4 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.

Research Excerpts

ExcerptRelevanceReference
" The chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), carboplatin, and camptothecin were incorporated into controlled-release polymers and tested individually against intracranial challenges with one of four tumors (lung carcinoma, renal cell carcinoma, colon carcinoma, and melanoma)."3.69Local delivery of chemotherapy and concurrent external beam radiotherapy prolongs survival in metastatic brain tumor models. ( Anderson, RC; Babel, KM; Brat, DJ; Brem, H; Ewend, MG; Pinn, ML; Tabassi, K; Tyler, BM; Williams, JA, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Teicher, BA3
Holden, SA1
Chen, YN1
Ara, G1
Korbut, TT1
Northey, D1
Dupuis, NP1
Robinson, MF1
Emi, Y1
Goff, DA1
Ewend, MG1
Williams, JA1
Tabassi, K1
Tyler, BM1
Babel, KM1
Anderson, RC1
Pinn, ML1
Brat, DJ1
Brem, H1
Kakeji, Y1

Other Studies

4 other studies available for carmustine and Carcinoma, Lewis Lung

ArticleYear
CAI: effects on cytotoxic therapies in vitro and in vivo.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:6

    Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pro

1994
Antiangiogenic treatment (TNP-470/minocycline) increases tissue levels of anticancer drugs in mice bearing Lewis lung carcinoma.
    Oncology research, 1995, Volume: 7, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carmustine; Cell Hypoxia; Cell Survival; Cisp

1995
Local delivery of chemotherapy and concurrent external beam radiotherapy prolongs survival in metastatic brain tumor models.
    Cancer research, 1996, Nov-15, Volume: 56, Issue:22

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Camptothecin; Carboplatin; Carcinoma; Carcin

1996
Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents.
    Investigational new drugs, 1997, Volume: 15, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Anti

1997