carmustine has been researched along with Cancer of Stomach in 49 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multi-institutional cooperative study of patients with locally advanced, recurrent, or metastatic gastric adenocarcinoma who had not previously received chemotherapy was conducted, prospectively randomizing patients to receive either doxorubicin or the three-drug combination, 5-fluorouracil (5-FU), doxorubicin (Adriamycin; Adria Laboratories, Columbus, Ohio), and BCNU (FAB)." | 5.06 | Analysis of a prospectively randomized comparison of doxorubicin versus 5-fluorouracil, doxorubicin, and BCNU in advanced gastric cancer: implications for future studies. ( Fox, RM; Gill, G; Levi, JA; Tattersall, MH; Thomson, D; Woods, RL, 1986) |
| "Thirty-two evaluable patients with advanced measurable gastric adenocarcinoma were treated with a combination of 5-fluorouracil, adriamycin, and BCNU (FAB)." | 5.05 | 5-fluorouracil, adriamycin, and BCNU (FAB) combination chemotherapy for advanced gastric cancer. ( Di Lauro, L; Lopez, M; Papaldo, P; Perno, CF, 1984) |
| "In a prospective, multi-centre, randomized study of 109 patients with metastatic gastro-intestinal adenocarcinomas the response rate, survival time and side-effects of two drug combinations, carmustin +5-fluorouracil and carmustin + ftorafur, were compared (same carmustin dosage in both groups)." | 5.04 | [A prospective multi-centre study of the response of metastatic gastrointestinal tumours (author's transl)]. ( Arnold, H; Drings, P; Geldmacher, J; Hartwich, G; Kredel, L; Mayer, M; Neidhardt, B; Queisser, W; Rösch, W; Schaefer, J; von Oldershausen, HF; Wahrendorf, J, 1979) |
| "Thirty-five patients with advanced-stage metastatic or unresectable gastric adenocarcinoma were given combination chemotherapy consisting of fluorouracil, doxorubicin, and 1,3-bis (2-chlorbethyl)-1-nitrosourea." | 3.66 | Improved combination chemotherapy in advanced gastric cancer. ( Aroney, RS; Dalley, DN; Levi, JA, 1979) |
| "Gastric cancer is the most chemotherapy-responsive adenocarcinoma of the major gastrointestinal sites." | 2.65 | Current management of advanced and locally unresectable gastric carcinoma. ( Ahlgren, JD; Schein, PS; Smith, FP; Woolley, PV, 1982) |
| "originates in the stomach." | 2.64 | Gastric cancer: current status of treatment. ( Carter, SK; Comis, RL, 1977) |
| "Gastric cancer is the second most frequent cause of cancer death worldwide, although much geographical variation in incidence exists." | 1.72 | Targeting Inhibition of Notch1 Signaling Pathway on the Study of Human Gastric Cancer Stem Cells with Chemosensitization. ( Dou, Y; Wang, J, 2022) |
| "First relapse was treated with high-dose BEAM chemotherapy and autologous peripheral blood stem cell transplantation (PBSCT)." | 1.30 | Treatment of relapsed non-Hodgkin's lymphoma after BEAM chemotherapy and autologous transplantation by BU/CY chemotherapy and salvage transplantation. ( Behringer, D; Fetscher, S; Finke, J; Kanz, L; Lange, W; Lübbert, M; Mertelsmann, R, 1997) |
| "Tegafur p." | 1.28 | Alternating chemotherapy in advanced gastric cancer. A phase II study. ( Barón-Saura, JM; Berrocal, A; Feliu, J; Girón, CG; González-Baron, M, 1991) |
| "In nine of 11 (82%) instances, tumors were sensitive to a particular drug, and the patient had at least 50% regression of tumor following treatment with the tested drug." | 1.26 | Clinical correlations with drug sensitivities in the clonogenic assay: a retrospective study. ( Burk, MW; Campbell, MA; Giuliano, AE; Kaiser, LR; Kern, DH; Mann, BD; Morton, DL, 1982) |
| "The therapy of cancer of the colon still remains unsatisfactory: the rate of remissions could be increased, but survival remains unaltered." | 1.26 | [Current state of therapy for gastrointestinal tumors]. ( Hartmann, D; Obrecht, JP, 1978) |
| "Although advanced gastrointestinal cancer is the most commonplace problem encountered by the medical oncologist, this group of diseases has proved exceedingly resistant to past chemotherapy efforts." | 1.25 | Clinical management of advanced gastrointestinal cancer. ( Moertel, CG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (87.76) | 18.7374 |
| 1990's | 4 (8.16) | 18.2507 |
| 2000's | 1 (2.04) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Dou, Y | 1 |
| Wang, J | 1 |
| Lawton, JO | 2 |
| Giles, GR | 2 |
| Hall, R | 1 |
| Bird, GG | 1 |
| Matheson, T | 1 |
| Mann, BD | 1 |
| Kern, DH | 1 |
| Giuliano, AE | 1 |
| Burk, MW | 1 |
| Campbell, MA | 1 |
| Kaiser, LR | 1 |
| Morton, DL | 1 |
| Queisser, W | 5 |
| Heim, ME | 3 |
| Lopez, M | 3 |
| Perno, CF | 1 |
| Di Lauro, L | 3 |
| Papaldo, P | 2 |
| Mutzner, F | 1 |
| Gunderson, LL | 1 |
| Hoskins, RB | 1 |
| Cohen, AC | 1 |
| Kaufman, S | 1 |
| Wood, WC | 1 |
| Carey, RW | 1 |
| Schnitzler, G | 2 |
| König, H | 2 |
| Katz, R | 2 |
| Fritze, D | 2 |
| Herrmann, R | 2 |
| Arnold, H | 3 |
| Henss, H | 2 |
| Trux, F | 1 |
| Schein, PS | 1 |
| Smith, FP | 1 |
| Woolley, PV | 1 |
| Ahlgren, JD | 1 |
| Gropp, C | 1 |
| Havemann, K | 1 |
| Jamieson, GG | 1 |
| Gill, PG | 1 |
| Schlag, P | 2 |
| Schreml, W | 1 |
| Gaus, W | 1 |
| Herfarth, C | 1 |
| Linder, MM | 1 |
| Trede, M | 1 |
| Joss, R | 1 |
| Goldhirsch, A | 1 |
| Tschopp, L | 1 |
| Brunner, K | 1 |
| Eisenbrand, G | 1 |
| Habs, M | 2 |
| Knorr, V | 1 |
| Schmitz, R | 1 |
| Fetscher, S | 1 |
| Lübbert, M | 1 |
| Kanz, L | 1 |
| Behringer, D | 1 |
| Finke, J | 1 |
| Mertelsmann, R | 1 |
| Lange, W | 1 |
| Wan, Y | 1 |
| Wu, D | 1 |
| Gao, H | 1 |
| Lu, H | 1 |
| Schmähl, D | 1 |
| Moertel, CG | 5 |
| Stephens, FO | 3 |
| Harker, GJ | 1 |
| Dickinson, RT | 1 |
| Roberts, BA | 1 |
| Schaefer, J | 1 |
| Drings, P | 1 |
| Geldmacher, J | 1 |
| Hartwich, G | 1 |
| Kredel, L | 1 |
| Mayer, M | 1 |
| Neidhardt, B | 1 |
| von Oldershausen, HF | 1 |
| Rösch, W | 1 |
| Wahrendorf, J | 1 |
| Carter, SK | 2 |
| Comis, RL | 2 |
| Levi, JA | 2 |
| Dalley, DN | 1 |
| Aroney, RS | 1 |
| Hartmann, D | 1 |
| Obrecht, JP | 1 |
| Falkson, G | 1 |
| van Eden, EB | 1 |
| Jochimsen, PR | 1 |
| Pearlman, NW | 1 |
| Lawton, RL | 1 |
| Natali, M | 1 |
| Tonini, G | 1 |
| Carpano, S | 1 |
| Vici, P | 1 |
| Conti, EM | 2 |
| Feliu, J | 1 |
| Girón, CG | 1 |
| González-Baron, M | 1 |
| Berrocal, A | 1 |
| Barón-Saura, JM | 1 |
| Adams, BG | 1 |
| Crea, P | 1 |
| Villar, A | 1 |
| Asensio, F | 1 |
| Candel, M | 1 |
| Delgado, F | 1 |
| Garcia, J | 1 |
| Lledó, S | 1 |
| Redón, J | 1 |
| Roig, JV | 1 |
| Sanchez, A | 1 |
| Sanchis, C | 1 |
| Keymling, M | 1 |
| Lübke, HJ | 1 |
| Wörner, W | 1 |
| De Lisi, V | 2 |
| Cocconi, G | 2 |
| Tonato, M | 2 |
| Di Costanzo, F | 2 |
| Leonardi, F | 2 |
| Soldani, M | 2 |
| Kim, RH | 1 |
| Lee, YW | 1 |
| Lee, DC | 1 |
| Kim, NH | 1 |
| Choi, JS | 1 |
| Joo, SK | 1 |
| Kim, CS | 1 |
| Trux, FA | 1 |
| Fox, RM | 1 |
| Tattersall, MH | 1 |
| Woods, RL | 1 |
| Thomson, D | 1 |
| Gill, G | 1 |
| Bukowski, RM | 1 |
| Theodors, A | 1 |
| Purvis, JD | 1 |
| Budd, GT | 1 |
| Weick, JK | 1 |
| Gahbauer, R | 1 |
| Klein, HO | 1 |
| Marsh, JC | 1 |
| DeConti, RC | 1 |
| Hubbard, SP | 1 |
| Tormey, DC | 1 |
| Gailani, S | 1 |
| Leone, L | 1 |
| Kovach, JS | 1 |
| Schutt, AJ | 1 |
| Hahn, RG | 1 |
| Reitemeier, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Trial of S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for First Line Treatment of Advanced Gastric Cancer[NCT01671449] | Phase 3 | 338 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for carmustine and Cancer of Stomach
| Article | Year |
|---|---|
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxor | 1981 |
Induction chemotherapy using intraarterial infusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Doxorubicin; Drug Evaluation; Humans; In | 1991 |
A review of chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Chlorambucil; Chromomycins; Cyclophosphamide; Cyt | 1974 |
16 trials available for carmustine and Cancer of Stomach
| Article | Year |
|---|---|
Chemotherapy following palliative resection of gastric cancer.
Topics: Aged; Carmustine; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Pallia | 1981 |
5-fluorouracil, adriamycin, and BCNU (FAB) combination chemotherapy for advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmustine | 1984 |
[Prospective randomized study in advanced stomach cancer. Comparison between combinations of 5-fluorouracil and carmustine without and with adriamycin].
Topics: Adult; Aged; Carmustine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukocyte Cou | 1984 |
Current management of advanced and locally unresectable gastric carcinoma.
Topics: Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; | 1982 |
A prospective trial of 5-FU and BCNU in the treatment of advanced gastric cancer.
Topics: Adult; Aged; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; | 1981 |
Adjuvant 5-fluorouracil and BCNU chemotherapy in gastric cancer: 3-year results.
Topics: Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Follow-Up | 1982 |
[A prospective multi-centre study of the response of metastatic gastrointestinal tumours (author's transl)].
Topics: Adenocarcinoma; Carmustine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; | 1979 |
Gastric cancer: current status of treatment.
Topics: Adenocarcinoma; Aged; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Ther | 1977 |
A controlled clinical trial of fluorouracil plus imidazole carboxamide dimethyl triazeno plus vincristine plus bis-chloroethyl nitrosourea plus radiotherapy in stomach cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Dacarbazin | 1976 |
Chemotherapy of advanced gastric carcinoma (stage IV): a randomized study of FAM versus 5-FU plus BCNU.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; D | 1987 |
5-Fluorouracil versus a combination of BCNU, adriamycin, 5-FU and mitomycin C in advanced gastric cancer: a prospective randomized study of the Italian Clinical Research Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; D | 1988 |
Advanced gastric carcinoma chemotherapy with cisplatin, mitomycin C, BCNU, and 5-fluorouracil in combination.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Female; Fluorour | 1987 |
Phase III study of 5-FU and carmustine versus 5-FU, carmustine, and doxorubicin in advanced gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; Doxorubicin; F | 1986 |
Randomized comparison of 5-FU alone or combined with carmustine, doxorubicin, and mitomycin (BAFMi) in the treatment of advanced gastric cancer: a phase III trial of the Italian Clinical Research Oncology Group (GOIRC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; D | 1986 |
Analysis of a prospectively randomized comparison of doxorubicin versus 5-fluorouracil, doxorubicin, and BCNU in advanced gastric cancer: implications for future studies.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Tr | 1986 |
Treatment of Hodgkin's disease and other cancers with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962).
Topics: Adenocarcinoma; Adenoma, Islet Cell; Adolescent; Adrenal Gland Neoplasms; Adult; Alkylating Agents; | 1971 |
30 other studies available for carmustine and Cancer of Stomach
| Article | Year |
|---|---|
Targeting Inhibition of Notch1 Signaling Pathway on the Study of Human Gastric Cancer Stem Cells with Chemosensitization.
Topics: Animals; Carmustine; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, S | 2022 |
Clinical correlations with drug sensitivities in the clonogenic assay: a retrospective study.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Hepatocellular; Carmustine; Cell Division; D | 1982 |
[State of chemotherapy and adjuvant therapies in the treatment of stomach cancer].
Topics: Carmustine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; Male; Middle Ag | 1984 |
Combined modality treatment of gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Doxorubicin; Drug Therap | 1983 |
[Chemotherapy of stomach cancer].
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cisplatin; Doxorubicin; Drug Administration Sched | 1982 |
[Gastrointestinal tumors. Prognostic factors and chemotherapy of today].
Topics: Carmustine; Colonic Neoplasms; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans | 1981 |
Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
Topics: Animals; Antineoplastic Agents; Carcinogens; Carmustine; Lomustine; Lung Neoplasms; Male; Neoplasms, | 1980 |
[Animal experiments using adjuvant 5-FU and BCNU chemotherapy in stomach cancer].
Topics: Animals; Carmustine; Drug Therapy, Combination; Fluorouracil; Mice; Mice, Inbred BALB C; Mice, Nude; | 1980 |
Treatment of relapsed non-Hodgkin's lymphoma after BEAM chemotherapy and autologous transplantation by BU/CY chemotherapy and salvage transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Combined Modality Ther | 1997 |
Potentiation of BCNU anticancer activity by O6-benzylguanine: a study in vitro and in vivo.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Car | 2000 |
Chemotherapy studies in autochthonous rat tumors: carcinomas of the forestomach.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Dimethylnitrosamine; Drug Evaluation, Preclin | 1979 |
Clinical management of advanced gastrointestinal cancer.
Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Ther | 1975 |
Walter Hubert lecture Chemotherapy of upper gastrointestinal carcinoma.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, S | 1976 |
Preoperative basal chemotherapy in the management of cancer of the stomach: a preliminary report.
Topics: Adult; Aged; Carmustine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infus | 1979 |
Improved combination chemotherapy in advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Carmustine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouraci | 1979 |
[Current state of therapy for gastrointestinal tumors].
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; | 1978 |
Chemotherapy for known residual disease after resection of gastric and colorectal cancer.
Topics: Carcinoembryonic Antigen; Carmustine; Colonic Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; H | 1978 |
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neo | 1976 |
Pancreatic carcinoma as a sequel to therapy of lymphoma.
Topics: Adenocarcinoma; Adolescent; Adult; Antineoplastic Agents; Carmustine; Cyclophosphamide; Female; Hodg | 1976 |
5-Fluorouracil, epirubicin, and BCNU (FEB) in advanced measurable gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Epirubicin; | 1990 |
Alternating chemotherapy in advanced gastric cancer. A phase II study.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Doxoru | 1991 |
Intra-arterial chemotherapy given preoperatively in the management of carcinoma of the stomach.
Topics: Adult; Aged; Antineoplastic Agents; Carmustine; Combined Modality Therapy; Doxorubicin; Female; Foll | 1986 |
[Chemotherapy and enteral nutrition in stomach cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; | 1988 |
Adjuvant chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality | 1987 |
Phase II trial of sequential chemotherapy and low-dose radiotherapy in advanced gastric adenocarcinoma. A Southwest Oncology Group Pilot Study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carm | 1987 |
Treatment of advanced measurable gastric carcinoma with 5-fluorouracil, adriamycin, and BCNU.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Doxorubicin; Female; Fluoro | 1986 |
Preoperative chemotherapy in patients with gastric cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Doxoru | 1985 |
Cancer of the gastrointestinal tract. Chemotherapy.
Topics: Antineoplastic Agents; Camptothecin; Carmustine; Cyclohexanes; Cyclophosphamide; Drug Therapy, Combi | 1974 |
Phase II evaluation of BCNU and 5-FU in gastrointestinal carcinomas.
Topics: Adenocarcinoma; Administration, Oral; Carmustine; Colonic Neoplasms; Diarrhea; Fluorouracil; Hematoc | 1974 |
Proceedings: A controlled study of combined 1,3-bis-(2-chloroethyl)-1-nitrosourea and 5-fluorouracil therapy for advanced gastric and pancreatic cancer.
Topics: Adenocarcinoma; Carmustine; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Mal | 1974 |