carmustine has been researched along with Cancer of Gastrointestinal Tract in 16 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective, multi-centre, randomized study of 109 patients with metastatic gastro-intestinal adenocarcinomas the response rate, survival time and side-effects of two drug combinations, carmustin +5-fluorouracil and carmustin + ftorafur, were compared (same carmustin dosage in both groups)." | 5.04 | [A prospective multi-centre study of the response of metastatic gastrointestinal tumours (author's transl)]. ( Arnold, H; Drings, P; Geldmacher, J; Hartwich, G; Kredel, L; Mayer, M; Neidhardt, B; Queisser, W; Rösch, W; Schaefer, J; von Oldershausen, HF; Wahrendorf, J, 1979) |
| " Part II of the trial revealed that neither a higher dosage of ftorafur (2 g/m2/day X 5 days) nor the addition of vincristine to both regimens changed the previously obtained results significantly." | 2.65 | Comparison of ftorafur with 5-fluorouracil in combination chemotherapy of advanced gastrointestinal carcinoma. ( Arnold, H; Drings, P; Fritze, D; Geldmacher, J; Hartwich, G; Herrmann, R; Kempf, P; König, H; Meiser, RJ; Nedden, R; Pappas, A; Queisser, W; Schaefer, J; Schnitzler, G; Sievers, H; von Oldershausen, HF; Wahrendorf, J; Westerhausen, M; Witte, S, 1981) |
| "The therapy of cancer of the colon still remains unsatisfactory: the rate of remissions could be increased, but survival remains unaltered." | 1.26 | [Current state of therapy for gastrointestinal tumors]. ( Hartmann, D; Obrecht, JP, 1978) |
| "Although advanced gastrointestinal cancer is the most commonplace problem encountered by the medical oncologist, this group of diseases has proved exceedingly resistant to past chemotherapy efforts." | 1.25 | Clinical management of advanced gastrointestinal cancer. ( Moertel, CG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borchard, F | 1 |
| Weiss, RB | 1 |
| Issell, BF | 1 |
| Queisser, W | 2 |
| Schnitzler, G | 1 |
| Schaefer, J | 2 |
| Arnold, H | 2 |
| Drings, P | 2 |
| Fritze, D | 1 |
| Geldmacher, J | 2 |
| Hartwich, G | 2 |
| Herrmann, R | 1 |
| Kempf, P | 1 |
| König, H | 1 |
| Meiser, RJ | 1 |
| Nedden, R | 1 |
| von Oldershausen, HF | 2 |
| Pappas, A | 1 |
| Sievers, H | 1 |
| Wahrendorf, J | 2 |
| Westerhausen, M | 1 |
| Witte, S | 1 |
| Joss, R | 1 |
| Goldhirsch, A | 1 |
| Tschopp, L | 1 |
| Brunner, K | 1 |
| Neumeister, P | 1 |
| Hoefler, G | 1 |
| Beham-Schmid, C | 1 |
| Sill, H | 1 |
| Linkesch, W | 1 |
| Moertel, CG | 4 |
| Kredel, L | 1 |
| Mayer, M | 1 |
| Neidhardt, B | 1 |
| Rösch, W | 1 |
| Hartmann, D | 1 |
| Obrecht, JP | 1 |
| Giles, GR | 1 |
| Lawton, JO | 1 |
| Brufman, G | 1 |
| Biran, S | 1 |
| Ratzkowski, E | 1 |
| Heim, ME | 1 |
| Marsh, JC | 1 |
| DeConti, RC | 1 |
| Hubbard, SP | 1 |
| Omura, GA | 1 |
| Roberts, GA | 1 |
2 reviews available for carmustine and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; C | 1982 |
The nitrosoureas: carmustine (BCNU) and lomustine (CCNU).
Topics: Bone Marrow; Brain Neoplasms; Carmustine; Drug Therapy, Combination; Gastrointestinal Neoplasms; Hod | 1982 |
3 trials available for carmustine and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Comparison of ftorafur with 5-fluorouracil in combination chemotherapy of advanced gastrointestinal carcinoma.
Topics: Adult; Carmustine; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Huma | 1981 |
[A prospective multi-centre study of the response of metastatic gastrointestinal tumours (author's transl)].
Topics: Adenocarcinoma; Carmustine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; | 1979 |
Treatment of Hodgkin's disease and other cancers with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962).
Topics: Adenocarcinoma; Adenoma, Islet Cell; Adolescent; Adrenal Gland Neoplasms; Adult; Alkylating Agents; | 1971 |
11 other studies available for carmustine and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
[Gastrointestinal tumors. Prognostic factors and chemotherapy of today].
Topics: Carmustine; Colonic Neoplasms; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans | 1981 |
Complete remission of generalized relapsed extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type of the gastrointestinal tract after high-dose chemotherapy and autologous peripheral stem cell transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Cytarabine; D | 2000 |
Clinical management of advanced gastrointestinal cancer.
Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Ther | 1975 |
Walter Hubert lecture Chemotherapy of upper gastrointestinal carcinoma.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, S | 1976 |
[Current state of therapy for gastrointestinal tumors].
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; | 1978 |
Chemotherapy for known residual disease after resection of gastric and colorectal cancer.
Topics: Carcinoembryonic Antigen; Carmustine; Colonic Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; H | 1978 |
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neo | 1976 |
[Results with new cytotoxic agents].
Topics: Carmustine; Dacarbazine; Gastrointestinal Neoplasms; Humans; Melanoma; Remission, Spontaneous; Triaz | 1976 |
[Intra-arterial chemotherapy of local recurrences of gastrointestinal tumors].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colorectal Neopla | 1989 |
Combination therapy of solid tumors using 1,3-bis(2-chloroethyl)-1-nitrosourea (NCNU), vincristine, methotrexate, and 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Carmustine; Female; Fluorouracil; Gastrointes | 1973 |
Therapy of advanced gastrointestinal cancer with the nitrosoureas.
Topics: Adenocarcinoma; Antineoplastic Agents; Bone Marrow Diseases; Carmustine; Colonic Neoplasms; Cyclohex | 1973 |