carmustine has been researched along with Cancer of Eye in 11 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective randomized phase III clinical trial was conducted to assess whether the addition of tamoxifen (TAM) to the three-agent regimen of cisplatin (CDDP), dacarbazine (DTIC), and carmustine (BCNU) significantly increased the progression-free survival and overall survival of patients with advanced malignant melanoma." | 9.09 | Phase III clinical trial of the combination of cisplatin, dacarbazine, and carmustine with or without tamoxifen in patients with advanced malignant melanoma. ( Creagan, ET; Dalton, RJ; Krook, JE; Long, HJ; Michalak, JC; Pitot, HC; Rowland, KM; Suman, VJ; Veeder, MH; Vukov, AM, 1999) |
| "A prospective randomized phase III clinical trial was conducted to assess whether the addition of tamoxifen (TAM) to the three-agent regimen of cisplatin (CDDP), dacarbazine (DTIC), and carmustine (BCNU) significantly increased the progression-free survival and overall survival of patients with advanced malignant melanoma." | 5.09 | Phase III clinical trial of the combination of cisplatin, dacarbazine, and carmustine with or without tamoxifen in patients with advanced malignant melanoma. ( Creagan, ET; Dalton, RJ; Krook, JE; Long, HJ; Michalak, JC; Pitot, HC; Rowland, KM; Suman, VJ; Veeder, MH; Vukov, AM, 1999) |
| "Sustained release of carmustine (1,3-bis[2-chloroethyl]-1-nitrosourea, or BCNU) via an episcleral implanted silicone device was used to treat Greene hamster melanoma implanted in the anterior chamber of rabbit eyes." | 3.66 | Sustained release of carmustine (BCNU) for treatment of experimental intraocular malignancy. ( Albert, DM; Liu, LH; Ni, C; Refojo, MF; Ueno, N, 1983) |
| "Greene melanoma was transplanted into the anterior chamber of rabbit eyes." | 1.26 | Experimental combined systemic and local chemotherapy for intraocular malignancy. ( Albert, DM; Liu, HS; Refojo, MF, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kremens, B | 1 |
| Wieland, R | 1 |
| Reinhard, H | 1 |
| Neubert, D | 1 |
| Beck, JD | 1 |
| Klingebiel, T | 1 |
| Bornfeld, N | 1 |
| Havers, W | 1 |
| Liu, XS | 1 |
| Murray, JL | 2 |
| Liu, LH | 1 |
| Refojo, MF | 5 |
| Ni, C | 1 |
| Ueno, N | 1 |
| Albert, DM | 4 |
| Robertson, DM | 1 |
| Wilkinson, CP | 1 |
| Gordy, DD | 1 |
| Liu, HS | 4 |
| Creagan, ET | 1 |
| Suman, VJ | 1 |
| Dalton, RJ | 1 |
| Pitot, HC | 1 |
| Long, HJ | 1 |
| Veeder, MH | 1 |
| Vukov, AM | 1 |
| Rowland, KM | 1 |
| Krook, JE | 1 |
| Michalak, JC | 1 |
| Perry, HD | 2 |
| Leong, FL | 1 |
| Sidebottom, D | 1 |
| Wysenbeek, YS | 1 |
| Nissenkorn, I | 1 |
| Cohen, S | 1 |
| Ben-Sira, I | 1 |
| Stark, B | 1 |
| Zaizov, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Standard Palliative Care Versus Standard Palliative Care Plus Polychemotherapy (CVD-Protocol) in the Second-Line Therapy of Distant Metastasized Malignant Melanoma[NCT00226473] | Phase 4 | 200 participants | Interventional | 2001-09-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for carmustine and Cancer of Eye
| Article | Year |
|---|---|
Phase III clinical trial of the combination of cisplatin, dacarbazine, and carmustine with or without tamoxifen in patients with advanced malignant melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplati | 1999 |
10 other studies available for carmustine and Cancer of Eye
| Article | Year |
|---|---|
High-dose chemotherapy with autologous stem cell rescue in children with retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmustine; Child; Child, Preschool; Co | 2003 |
[A new approach to chemotherapy for intraocular tumors (author's transl)].
Topics: Animals; Antineoplastic Agents; Carmustine; Eye Neoplasms; Female; Rabbits | 1980 |
Primary malignant melanoma metastatic to vitreous humor of the eye: treatment with BCNU.
Topics: Adult; Carmustine; Eye Neoplasms; Female; Humans; Melanoma; Vitreous Body | 1983 |
Sustained release of carmustine (BCNU) for treatment of experimental intraocular malignancy.
Topics: Animals; Anterior Chamber; Carmustine; Cricetinae; Delayed-Action Preparations; Eye Neoplasms; Femal | 1983 |
Metastatic tumor to the retina and vitreous cavity from primary melanoma of the skin: treatment with systemic and subconjunctival chemotherapy.
Topics: Adult; Carmustine; Dacarbazine; Eye Neoplasms; Female; Humans; Lomustine; Melanoma; Retina; Skin Neo | 1981 |
Experimental combined systemic and local chemotherapy for intraocular malignancy.
Topics: Animals; Carmustine; Ciliary Body; Eye Neoplasms; Female; Injections; Injections, Intravenous; Iris; | 1980 |
Sustained release of BCNU for the treatment of intraocular malignancies in animal models.
Topics: Animals; Anterior Chamber; Carcinoma, Brown-Pearce; Carmustine; Drug Implants; Ethanol; Eye Neoplasm | 1979 |
Direct delivery of anticancer agents: experimental treatment of intraocular malignancy.
Topics: Animals; Anterior Chamber; Carcinoma, Brown-Pearce; Carmustine; Conjunctiva; Dacarbazine; Eye Neopla | 1978 |
Release of a nitrosourea derivative from refillable silicone rubber implants for the treatment of intraocular malignancies.
Topics: Carmustine; Diffusion; Drug Implants; Eye Neoplasms; Humans; In Vitro Techniques; Silicones; Solvent | 1978 |
Intraocular involvement of Burkitt's lymphoma in a Bedouin child.
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Burkitt Lympho | 1987 |