carmustine has been researched along with Brain Diseases in 16 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the safety of thrice-daily hyperfractionated radiotherapy (RT) given in conjunction with BCNU (carmustine) in high-grade gliomas." | 5.10 | Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas. ( Buckner, JC; Dinapoli, RP; Earle, JD; O'Fallon, J; Rao, RD; Thomé, SD, 2002) |
| "Eight patients with advanced breast cancer were entered into a prospective, longitudinal trial that included examination by MR imaging and proton MR spectroscopy before chemotherapy and through 12 months after treatment with carmustine, cyclophosphamide, and cisplatin, combined with autologous hematopoietic progenitor cell support (AHPCS)." | 3.70 | White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. ( Brown, MS; Cagnoni, PJ; Jones, RB; Sheeder, JL; Simon, JH; Stears, JC; Stemmer, SM, 1998) |
| "Eighteen patients had carmustine (BCNU) wafers implanted during reoperation for malignant glioma; three patients had empty, placebo wafers placed." | 3.70 | Serial CT and MR imaging of carmustine wafers. ( Chiowanich, P; Cozzens, JW; Gorey, MT; Grenier, Y; Meyer, JR; Prager, JM, 2000) |
| "The hypodense, roughly spherical cysts clearly demonstrated clinically significant mass effect, and required reoperation despite treatment with high-dose corticosteroids." | 1.31 | Tumor bed cyst formation after BCNU wafer implantation: report of two cases. ( Engelhard, HH, 2000) |
| "Fatal leukoencephalopathy occurred in two patients." | 1.27 | Pre-irradiation internal carotid artery BCNU in treatment of glioblastoma multiforme. ( Bashir, R; Hochberg, FH; Hottleman, K; Linggood, RM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uyanikgil, Y | 1 |
| Baka, M | 1 |
| Ateş, U | 1 |
| Turgut, M | 1 |
| Yavaşoğlu, A | 1 |
| Ulker, S | 1 |
| Sözmen, EY | 1 |
| Sezer, E | 1 |
| Elmas, C | 1 |
| Yurtseven, ME | 1 |
| Yamamoto, YL | 1 |
| Thompson, CJ | 1 |
| Diksic, M | 1 |
| Meyer, E | 1 |
| Feindel, WH | 1 |
| Rubin, P | 1 |
| Brown, MS | 1 |
| Stemmer, SM | 1 |
| Simon, JH | 1 |
| Stears, JC | 1 |
| Jones, RB | 1 |
| Cagnoni, PJ | 1 |
| Sheeder, JL | 1 |
| Prager, JM | 1 |
| Grenier, Y | 1 |
| Cozzens, JW | 1 |
| Chiowanich, P | 1 |
| Gorey, MT | 1 |
| Meyer, JR | 1 |
| Engelhard, HH | 1 |
| Rao, RD | 1 |
| Thomé, SD | 1 |
| O'Fallon, J | 1 |
| Earle, JD | 1 |
| Dinapoli, RP | 1 |
| Buckner, JC | 1 |
| Schuler, D | 1 |
| Koós, R | 1 |
| Krauze, I | 1 |
| Péter, A | 1 |
| Ghatak, NR | 1 |
| Sawyer, DR | 1 |
| Tonn, JC | 1 |
| Roosen, K | 1 |
| Schachenmayr, W | 1 |
| Rosenblum, MK | 1 |
| Delattre, JY | 1 |
| Walker, RW | 1 |
| Shapiro, WR | 3 |
| Bashir, R | 1 |
| Hochberg, FH | 1 |
| Linggood, RM | 1 |
| Hottleman, K | 1 |
| Wolff, SN | 1 |
| Phillips, GL | 1 |
| Herzig, GP | 1 |
| Green, SB | 1 |
| Kapp, JP | 1 |
| Sanford, RA | 1 |
| Chernik, NL | 1 |
| Posner, JB | 1 |
2 reviews available for carmustine and Brain Diseases
| Article | Year |
|---|---|
Positron emission tomography.
Topics: Adolescent; Adult; Aged; Aging; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebrovascular | 1984 |
The Franz Buschke lecture: late effects of chemotherapy and radiation therapy: a new hypothesis.
Topics: Antineoplastic Agents; Bleomycin; Bone Marrow Diseases; Brain Diseases; Cardiomyopathies; Carmustine | 1984 |
2 trials available for carmustine and Brain Diseases
| Article | Year |
|---|---|
Safety of thrice-daily hyperfractionated radiation and BCNU for high-grade gliomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Diseases; Carm | 2002 |
Reevaluating the efficacy of intra-arterial BCNU.
Topics: Brain Diseases; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Glioma; Humans; Infusions, In | 1987 |
12 other studies available for carmustine and Brain Diseases
| Article | Year |
|---|---|
Neuroprotective effects of melatonin upon the offspring cerebellar cortex in the rat model of BCNU-induced cortical dysplasia.
Topics: Animals; Animals, Newborn; Brain Diseases; Bromodeoxyuridine; Carmustine; Cerebellar Cortex; Disease | 2007 |
White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain; Brain Diseases; B | 1998 |
Serial CT and MR imaging of carmustine wafers.
Topics: Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Diseases; Carmustine; Drug Deliver | 2000 |
Tumor bed cyst formation after BCNU wafer implantation: report of two cases.
Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuva | 2000 |
Paraneoplastic syndrome in childhood.
Topics: Brain Diseases; Carmustine; Child, Preschool; Humans; Lomustine; Male; Mediastinal Neoplasms; Methot | 1977 |
A morphologic study of opportunistic cerebral toxoplasmosis.
Topics: Aged; Brain Diseases; Carmustine; Hodgkin Disease; Humans; Male; Prednisone; Procarbazine; Radionucl | 1978 |
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therap | 1991 |
Fatal necrotizing encephalopathy complicating treatment of malignant gliomas with intra-arterial BCNU and irradiation: a pathological study.
Topics: Brain Diseases; Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioma; Humans; Infusions, I | 1989 |
Pre-irradiation internal carotid artery BCNU in treatment of glioblastoma multiforme.
Topics: Adult; Brain Diseases; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Combined Modality Ther | 1988 |
High-dose carmustine with autologous bone marrow transplantation for the adjuvant treatment of high-grade gliomas of the central nervous system.
Topics: Adult; Aged; Astrocytoma; Bone Marrow Transplantation; Brain Diseases; Brain Neoplasms; Carmustine; | 1987 |
Neurological deficit after carotid infusion of cisplatin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for malignant glioma: an analysis of risk factors.
Topics: Brain Diseases; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Cisplatin; Glioma; Humans; In | 1986 |
Necrotizing encephalopathy following intraventricular instillation of methotrexate.
Topics: Adolescent; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Cerebral Ventr | 1973 |