carmustine has been researched along with Anoxemia in 12 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study changes in glutathione redox status as an indicator of oxidant stress during hypoxia and reoxygenation, we perfused isolated rat lungs with a high or low oxygen perfusate and measured the release of total glutathione and glutathione disulfide (GSSG) into the perfusate." | 7.67 | Glutathione disulfide formation occurring during hypoxia and reoxygenation of rat lung. ( Jenkinson, SG; Jordan, JM; Lawrence, RA; Marcum, RF; Orzechowski, Z; Pickard, JS, 1988) |
| "Thus, hypoxia and anoxia impair the capability of cells to supply NADPH for the reduction of thiol oxidants." | 5.28 | Oxygen dependence of oxidative stress. Rate of NADPH supply for maintaining the GSH pool during hypoxia. ( Jones, DP; Tribble, DL, 1990) |
| "To study changes in glutathione redox status as an indicator of oxidant stress during hypoxia and reoxygenation, we perfused isolated rat lungs with a high or low oxygen perfusate and measured the release of total glutathione and glutathione disulfide (GSSG) into the perfusate." | 3.67 | Glutathione disulfide formation occurring during hypoxia and reoxygenation of rat lung. ( Jenkinson, SG; Jordan, JM; Lawrence, RA; Marcum, RF; Orzechowski, Z; Pickard, JS, 1988) |
| " This drug combination significantly impaired the sphere-forming ability of GSCs in vitro and tumor formation in vivo, leading to increase in the overall survival of mice bearing orthotopic inoculation of GSCs." | 1.39 | Effective elimination of cancer stem cells by a novel drug combination strategy. ( Chen, G; Colman, H; Feng, L; Huang, P; Keating, MJ; Li, X; Wang, F; Wang, J; Wang, L; Xu, RH; Yuan, S; Zhang, H, 2013) |
| "Thus, hypoxia and anoxia impair the capability of cells to supply NADPH for the reduction of thiol oxidants." | 1.28 | Oxygen dependence of oxidative stress. Rate of NADPH supply for maintaining the GSH pool during hypoxia. ( Jones, DP; Tribble, DL, 1990) |
| "Ten patients developed pulmonary fibrosis after bischloroethylnitrosourea (BCNU) therapy for malignancy." | 1.26 | Pulmonary toxicity associated with bischloroethylnitrosourea (BCNU). ( Bartolucci, AA; Durant, JR; Langford, KH; Murad, TM; Norgard, MJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, S | 1 |
| Wang, F | 1 |
| Chen, G | 1 |
| Zhang, H | 1 |
| Feng, L | 1 |
| Wang, L | 1 |
| Colman, H | 1 |
| Keating, MJ | 1 |
| Li, X | 1 |
| Xu, RH | 1 |
| Wang, J | 1 |
| Huang, P | 1 |
| Hettiarachchi, NT | 1 |
| Wilkinson, JA | 1 |
| Boyle, JP | 1 |
| Peers, C | 1 |
| Kennedy, KA | 1 |
| Siegfried, JM | 1 |
| Sartorelli, AC | 1 |
| Tritton, TR | 1 |
| Durant, JR | 1 |
| Norgard, MJ | 1 |
| Murad, TM | 1 |
| Bartolucci, AA | 1 |
| Langford, KH | 1 |
| Stanley, JA | 1 |
| Shipley, WU | 1 |
| Steel, GG | 1 |
| Tribble, DL | 1 |
| Jones, DP | 1 |
| Wolff, SN | 1 |
| Phillips, GL | 1 |
| Herzig, GP | 1 |
| Martin, DF | 1 |
| Kimler, BF | 1 |
| Evans, RG | 1 |
| Morantz, RA | 1 |
| Vats, TS | 1 |
| Jenkinson, SG | 1 |
| Marcum, RF | 1 |
| Pickard, JS | 1 |
| Orzechowski, Z | 1 |
| Lawrence, RA | 1 |
| Jordan, JM | 1 |
| White, CW | 1 |
| Jackson, JH | 1 |
| McMurtry, IF | 1 |
| Repine, JE | 1 |
| Siemann, DW | 1 |
| Mulcahy, RT | 1 |
| Reissmann, KR | 1 |
| Udupa, KB | 1 |
| Kawada, K | 1 |
12 other studies available for carmustine and Anoxemia
| Article | Year |
|---|---|
Effective elimination of cancer stem cells by a novel drug combination strategy.
Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Dacar | 2013 |
Hypoxic remodelling of Ca2+signalling in SH-SY5Y cells: influence of glutathione.
Topics: Bradykinin; Buthionine Sulfoximine; Calcium Signaling; Carmustine; Cell Line, Tumor; Cell Survival; | 2007 |
Effects of anthracyclines on oxygenated and hypoxic tumor cells.
Topics: Animals; Antibiotics, Antineoplastic; Carmustine; Cell Survival; Chromatography, High Pressure Liqui | 1983 |
Pulmonary toxicity associated with bischloroethylnitrosourea (BCNU).
Topics: Adolescent; Adult; Aged; Carmustine; Cough; Dyspnea; Female; Humans; Hypoxia; Lymphoma; Male; Middle | 1979 |
Influence of tumour size on hypoxic fraction and therapeutic sensitivity of Lewis lung tumour.
Topics: Animals; Carmustine; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Radiation; Gamma R | 1977 |
Oxygen dependence of oxidative stress. Rate of NADPH supply for maintaining the GSH pool during hypoxia.
Topics: Animals; Carmustine; Citrates; Citric Acid; Diamide; Glucose; Glutathione; Glutathione Reductase; Hy | 1990 |
High-dose carmustine with autologous bone marrow transplantation for the adjuvant treatment of high-grade gliomas of the central nervous system.
Topics: Adult; Aged; Astrocytoma; Bone Marrow Transplantation; Brain Diseases; Brain Neoplasms; Carmustine; | 1987 |
Potentiation of rat brain tumor therapy by fluosol and carbogen.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carbon Dioxide; Carmustine | 1988 |
Glutathione disulfide formation occurring during hypoxia and reoxygenation of rat lung.
Topics: Animals; Carmustine; Glutathione; Glutathione Disulfide; Hypoxia; L-Lactate Dehydrogenase; Liver; Lu | 1988 |
Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants.
Topics: 6-Aminonicotinamide; Animals; Carmustine; Glutathione; Hydrogen Peroxide; Hypoxia; In Vitro Techniqu | 1988 |
Sensitization of cancer chemotherapeutic agents by nitroheterocyclics.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Survival; Drug Synergism; | 1986 |
Effects of erythropoietin and androgens on erythroid stem cells after their selective suppression by BCNU.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Erythrocyte Aging; Erythropoiesi | 1974 |