Page last updated: 2024-10-24

carmustine and Amyloidosis

carmustine has been researched along with Amyloidosis in 3 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

Research Excerpts

ExcerptRelevanceReference
"Therapy with multiple alkylating agents did not result in a higher response rate or longer survival time, compared with standard melphalan and prednisone treatment in patients with primary systemic amyloidosis."9.09Prospective randomized trial of melphalan and prednisone versus vincristine, carmustine, melphalan, cyclophosphamide, and prednisone in the treatment of primary systemic amyloidosis. ( Gertz, MA; Greipp, PR; Kyle, RA; Lacy, MQ; Lust, JA; Witzig, TE, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mahendra, P1
Johnson, D1
Scott, MA1
Jestice, HK1
Hood, IM1
Ager, S1
Bass, G1
Barker, P1
Boraks, PA1
Bloxham, DM1
Baglin, TP1
Marcus, RE1
Gertz, MA2
Lacy, MQ2
Dispenzieri, A1
Lust, JA1
Greipp, PR1
Witzig, TE1
Kyle, RA1

Reviews

1 review available for carmustine and Amyloidosis

ArticleYear
Peripheral blood progenitor cell transplantation: a single centre experience comparing two mobilisation regimens in 67 patients.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmust

1996

Trials

2 trials available for carmustine and Amyloidosis

ArticleYear
Peripheral blood progenitor cell transplantation: a single centre experience comparing two mobilisation regimens in 67 patients.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmust

1996
Prospective randomized trial of melphalan and prednisone versus vincristine, carmustine, melphalan, cyclophosphamide, and prednisone in the treatment of primary systemic amyloidosis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Amyloidosis; Carmustine; Cyclophosphamide; Drug T

1999

Other Studies

1 other study available for carmustine and Amyloidosis

ArticleYear
Amyloidosis: recognition, confirmation, prognosis, and therapy.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:5

    Topics: Aged; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Dia

1999