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carmustine and Alzheimer Disease

carmustine has been researched along with Alzheimer Disease in 4 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayes, CD1
Dey, D1
Palavicini, JP1
Wang, H1
Patkar, KA1
Minond, D1
Nefzi, A1
Lakshmana, MK1
Araki, W1
Keimowitz, RM1
Tamada, J1
Langer, R1

Reviews

1 review available for carmustine and Alzheimer Disease

ArticleYear
The development of polyanhydrides for drug delivery applications.
    Journal of biomaterials science. Polymer edition, 1992, Volume: 3, Issue:4

    Topics: Alzheimer Disease; Anhydrides; Animals; Bethanechol; Bethanechol Compounds; Biocompatible Materials;

1992

Trials

1 trial available for carmustine and Alzheimer Disease

ArticleYear
The development of polyanhydrides for drug delivery applications.
    Journal of biomaterials science. Polymer edition, 1992, Volume: 3, Issue:4

    Topics: Alzheimer Disease; Anhydrides; Animals; Bethanechol; Bethanechol Compounds; Biocompatible Materials;

1992

Other Studies

3 other studies available for carmustine and Alzheimer Disease

ArticleYear
Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.
    BMC medicine, 2013, Mar-26, Volume: 11

    Topics: Alzheimer Disease; Animals; Antineoplastic Agents, Alkylating; Brain; Carmustine; CHO Cells; Criceti

2013
Potential repurposing of oncology drugs for the treatment of Alzheimer's disease.
    BMC medicine, 2013, Mar-26, Volume: 11

    Topics: Alzheimer Disease; Animals; Antineoplastic Agents, Alkylating; Carmustine; Neuroprotective Agents; P

2013
Dementia improvement with cytotoxic chemotherapy. A case of Alzheimer disease and multiple myeloma.
    Archives of neurology, 1997, Volume: 54, Issue:4

    Topics: Alzheimer Disease; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Hum

1997