carmustine has been researched along with Agranulocytosis in 9 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-four patients with progressive symptomatic multiple myeloma were treated with a protocol combining cyclophosphamide (10 mg/kg weekly), procarbazine (2 mg/kg daily), prednisolone (20 mg daily), and either BCNU (1 mg/kg weekly) (BCPP protocol) or MCNU (0." | 7.67 | [Combination chemotherapy of multiple myeloma--BCNU.cyclophosphamide.procarbazine.prednisolone and MCNU.cyclophosphamide.procarbazine.prednisolone therapy]. ( Ito, T; Komatsu, M; Saito, Y; Takahashi, H; Uzuka, Y, 1989) |
| "Forty-four patients with progressive symptomatic multiple myeloma were treated with a protocol combining cyclophosphamide (10 mg/kg weekly), procarbazine (2 mg/kg daily), prednisolone (20 mg daily), and either BCNU (1 mg/kg weekly) (BCPP protocol) or MCNU (0." | 3.67 | [Combination chemotherapy of multiple myeloma--BCNU.cyclophosphamide.procarbazine.prednisolone and MCNU.cyclophosphamide.procarbazine.prednisolone therapy]. ( Ito, T; Komatsu, M; Saito, Y; Takahashi, H; Uzuka, Y, 1989) |
| "Sixteen patients with advanced (stage III) malignant melanoma were treated with escalating doses of intravenous BCNU and melphalan starting at 400 and 35 mg/m2, respectively, and escalating to 1,000 and 110 mg/m2, respectively, combined with autologous marrow transplantation." | 3.67 | Recovery of blood and bone marrow stem cells following intense chemotherapy and autologous bone marrow transplantation. ( Glode, LM; Morton, N; Mughal, TI; Robinson, WA; Thomas, MR, 1986) |
| "Thirty-one patients with resistant Hodgkin's disease were treated by an identical high dose chemotherapy regimen and autologous bone marrow transplantation." | 2.66 | GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease. ( Devereaux, S; Goldstone, AH; Gribben, JG; Linch, DC; McMillan, A; Patterson, K, 1989) |
| "Skin, lymph node, and soft tissue metastases more frequently responded to therapy, while hepatic, peritoneal, and osseous metastases responded with an intermediate frequency." | 1.26 | Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC 409962) and cyclophosphamide therapy of drug-resistant metastatic breast carcinoma. ( Klahr, C; Presant, CA; Van Amburg, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Presant, CA | 2 |
| Bartolucci, A | 1 |
| Van Amburg, A | 1 |
| Klahr, C | 1 |
| Udupa, KB | 2 |
| Reissmann, KR | 2 |
| Spitzer, G | 1 |
| Deisseroth, A | 1 |
| Ventura, G | 1 |
| Jagannath, S | 1 |
| Fogel, B | 1 |
| Taylor, K | 1 |
| Huan, S | 1 |
| Dunphy, F | 1 |
| Dicke, K | 1 |
| Souza, L | 1 |
| Devereaux, S | 1 |
| Linch, DC | 1 |
| Gribben, JG | 1 |
| McMillan, A | 1 |
| Patterson, K | 1 |
| Goldstone, AH | 1 |
| Uzuka, Y | 1 |
| Saito, Y | 1 |
| Takahashi, H | 1 |
| Komatsu, M | 1 |
| Ito, T | 1 |
| Thomas, MR | 1 |
| Robinson, WA | 1 |
| Mughal, TI | 1 |
| Morton, N | 1 |
| Glode, LM | 1 |
1 trial available for carmustine and Agranulocytosis
| Article | Year |
|---|---|
GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmus | 1989 |
8 other studies available for carmustine and Agranulocytosis
| Article | Year |
|---|---|
Adriamycin, BCNU, and cyclophosphamide in drug-resistant adenocarcinoma of the ovary.
Topics: Adenocarcinoma; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cycloph | 1983 |
Alternative mechanisms for severe neutropenia.
Topics: Agranulocytosis; Carmustine; Cimetidine; Drug Interactions; Humans; Neutropenia | 1982 |
Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC 409962) and cyclophosphamide therapy of drug-resistant metastatic breast carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Agranulocytosis; Ascites; Bone Neoplasms; Breast Neoplasms; Carmustine; | 1977 |
Stimulation of granulopoiesis by androgens without concomitant increase in the serum level of colony stimulating factor.
Topics: Agranulocytosis; Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Colony-Stimulat | 1975 |
Use of recombinant human hematopoietic growth factors and autologous bone marrow transplantation to attenuate the neutropenic trough of high-dose therapy.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Specimen Co | 1990 |
[Combination chemotherapy of multiple myeloma--BCNU.cyclophosphamide.procarbazine.prednisolone and MCNU.cyclophosphamide.procarbazine.prednisolone therapy].
Topics: Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Agents; Antineoplastic Combined Chemotherap | 1989 |
Recovery of blood and bone marrow stem cells following intense chemotherapy and autologous bone marrow transplantation.
Topics: Agranulocytosis; Bone Marrow Transplantation; Carmustine; Colony-Forming Units Assay; Hematopoietic | 1986 |
Acceleration of granulopoietic recovery by androgenic steroids in mice made neutropenic by cytotoxic drugs.
Topics: Agranulocytosis; Androgens; Animals; Bone Marrow; Busulfan; Carmustine; Cell Division; Clone Cells; | 1974 |