carmustine and Aging
carmustine has been researched along with Aging in 7 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of postmaturational aging on the toxicity of diquat, a redox cycling compound, were investigated in hepatocytes that were isolated from mature (6 months) and old (27 months) male Fischer 344 rats and pretreated with 1,3-bis(2-chloroethyl)-1- nitrosourea (BCNU), an inhibitor of glutathione reductase." | 3.68 | Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats. ( Cai, Y; Rikans, LE, 1993) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chaichana, KL | 1 |
| Chaichana, KK | 1 |
| Olivi, A | 1 |
| Weingart, JD | 1 |
| Bennett, R | 1 |
| Brem, H | 1 |
| Quiñones-Hinojosa, A | 1 |
| Yamamoto, YL | 1 |
| Thompson, CJ | 1 |
| Diksic, M | 1 |
| Meyer, E | 1 |
| Feindel, WH | 1 |
| Navarra, S | 1 |
| Melita, P | 1 |
| Di Mauro, S | 1 |
| Rikans, LE | 1 |
| Cai, Y | 1 |
| Greenstein, RJ | 1 |
| Feleszko, W | 1 |
| Zagozdzon, R | 1 |
| Jakobisiak, M | 1 |
| Teller, MN | 1 |
| Bowie, M | 1 |
| Mountain, IM | 1 |
Reviews
1 review available for carmustine and Aging
| Article | Year |
|---|---|
Positron emission tomography.
Topics: Adolescent; Adult; Aged; Aging; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebrovascular | 1984 |
Other Studies
6 other studies available for carmustine and Aging
| Article | Year |
|---|---|
Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neopl | 2011 |
[Immunotherapy in the treatment of colorectal cancers in the aged].
Topics: Aged; Aging; BCG Vaccine; Carmustine; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Middle | 1982 |
Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats.
Topics: Aging; Animals; Carmustine; Diquat; Dose-Response Relationship, Drug; Glutathione; Hydroxides; Hydro | 1993 |
Age, as well as cell turnover kinetics, regulates brain/gut repair.
Topics: Aging; Animals; Brain; Carmustine; Cell Cycle; Cholecystokinin; DNA; DNA Damage; Intestinal Mucosa; | 1993 |
Re: Greying of America will foster new strategies in oncology.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylatin | 1998 |
Influence of age of host on the chemotherapy of murine myeloma LCP-1.
Topics: Age Factors; Aging; Alkylating Agents; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; | 1974 |