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carmustine and Aging

carmustine has been researched along with Aging in 7 studies

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The effects of postmaturational aging on the toxicity of diquat, a redox cycling compound, were investigated in hepatocytes that were isolated from mature (6 months) and old (27 months) male Fischer 344 rats and pretreated with 1,3-bis(2-chloroethyl)-1- nitrosourea (BCNU), an inhibitor of glutathione reductase."3.68Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats. ( Cai, Y; Rikans, LE, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaichana, KL1
Chaichana, KK1
Olivi, A1
Weingart, JD1
Bennett, R1
Brem, H1
QuiƱones-Hinojosa, A1
Yamamoto, YL1
Thompson, CJ1
Diksic, M1
Meyer, E1
Feindel, WH1
Navarra, S1
Melita, P1
Di Mauro, S1
Rikans, LE1
Cai, Y1
Greenstein, RJ1
Feleszko, W1
Zagozdzon, R1
Jakobisiak, M1
Teller, MN1
Bowie, M1
Mountain, IM1

Reviews

1 review available for carmustine and Aging

ArticleYear
Positron emission tomography.
    Neurosurgical review, 1984, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebrovascular

1984

Other Studies

6 other studies available for carmustine and Aging

ArticleYear
Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article.
    Journal of neurosurgery, 2011, Volume: 114, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neopl

2011
[Immunotherapy in the treatment of colorectal cancers in the aged].
    Minerva medica, 1982, Apr-28, Volume: 73, Issue:18

    Topics: Aged; Aging; BCG Vaccine; Carmustine; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Middle

1982
Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats.
    Toxicology and applied pharmacology, 1993, Volume: 118, Issue:2

    Topics: Aging; Animals; Carmustine; Diquat; Dose-Response Relationship, Drug; Glutathione; Hydroxides; Hydro

1993
Age, as well as cell turnover kinetics, regulates brain/gut repair.
    Mechanisms of ageing and development, 1993, Volume: 69, Issue:3

    Topics: Aging; Animals; Brain; Carmustine; Cell Cycle; Cholecystokinin; DNA; DNA Damage; Intestinal Mucosa;

1993
Re: Greying of America will foster new strategies in oncology.
    Journal of the National Cancer Institute, 1998, Feb-04, Volume: 90, Issue:3

    Topics: Aging; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

1998
Influence of age of host on the chemotherapy of murine myeloma LCP-1.
    Journal of gerontology, 1974, Volume: 29, Issue:4

    Topics: Age Factors; Aging; Alkylating Agents; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide;

1974